122, Tyrrelway West Hendon The Hyde, Middlesex NW9 7QP London, United KingdomKGN Ingredients is located in central India and is engaged in sourcing, marketing and distribution of food, feed and pharmaceutical ingredients worldwide.

Profile West, 950 Great West Road, Brentford,, England, TW8 9ES United KingdomSince 2014 ProRelix Research has been supporting our clients with outstanding clinical research services. The successful growth of ProRelix Research has been achieved by putting high quality and client focus at the heart of everything we do. We leverage our experience and expertise at the early stages of discussions with our clients to freely advise them on the optimal project plan. We then reach decision with each client on the scope of service, timelines and budget. ProRelix Research then commits to deliver those services on time and within budget – according to our End-to-End Guarantee. Our commitment to guaranteed delivery is unique in the clinical research environment which is otherwise notable for the routine occurrence of delays and cost overruns. Acting through Pharmaceutical, Medical Device Research teams, and with a comprehensive portfolio of services, we offer a flexible approach to ensure ProRelix Research optimally support the unique needs of each client. This could mean providing regulatory consultancy to a small company at the early stages of development programme, through to provision of full services to a company performing an international mega trial to support registration of their product. Whatever the size and scope of the project, each receives the same level of attention to detail and commitment to delivery of a high quality service within budget and to timelines agreed.

Pennyfoot Street Pennyfoot St England, NG1 1GF United KingdomPlatelet Solutions Ltd is a spin-out company of the University of Nottingham formed in 2011, and is the outcome of many years of research and experience in the Thrombosis and Haemostasis Group. The company focuses on the provision of products and services for platelet function testing. Platelet function testing is required for diagnosis of abnormal bleeding and to monitor platelet function in those who are at-risk of vascular events such as heart attack or stroke. Previously, platelet function analysis had to be performed immediately after taking the blood sample but our patented method allows samples to be processed using simple disposable kits and be posted for expert analysis. Our aim is to make platelet function testing reliable and accessible to everyone.

Biocity Pennyfoot St Nottingham, nottinghamshire, NG7 1TL United KingdomPlatelet Solutions Ltd is a spin-out company of the University of Nottingham formed in 2011, and is the outcome of many years of research and experience in the Thrombosis and Haemostasis Group. The company focuses on the provision of products and services for platelet function testing. Platelet function testing is required for diagnosis of abnormal bleeding and to monitor platelet function in those who are at-risk of vascular events such as heart attack or stroke. Previously, platelet function analysis had to be performed immediately after taking the blood sample but our patented method allows samples to be processed using simple disposable kits and be posted for expert analysis. Our aim is to make platelet function testing reliable and accessible to everyone.

Box 178 Addenbrookes Hospital Hills Road Cambridge CB2 0QQThis is a facility for smart storage, processing, retrieval and rearraying of samples prior to high throughput measurements, is being established as a collaboration between the NIHR Cambridge BRC, the MRC Epidemiology Unit and the University of Cambridge. The University has provided the space, with the costs of refurbishment and capital coming from NIHR Cambridge BRC and the MRC Epidemiology Unit. This facility will be overseen by a management committee with representation from NIHR Cambridge BRC, the University and MRC and will be run on a cost recovery basis by the partners.

Hills Road Cambridge, England, CB2 United KingdomThis is a facility for smart storage, processing, retrieval and rearraying of samples prior to high throughput measurements, is being established as a collaboration between the NIHR Cambridge BRC, the MRC Epidemiology Unit and the University of Cambridge. The University has provided the space, with the costs of refurbishment and capital coming from NIHR Cambridge BRC and the MRC Epidemiology Unit. This facility will be overseen by a management committee with representation from NIHR Cambridge BRC, the University and MRC and will be run on a cost recovery basis by the partners.

24 Broughton Street Scotland, EH1 3RH United KingdomWe specialise in designing and conducting safety, efficacy, acceptability and preference testing for a range of markets worldwide which include, household and personal care, cosmetic, healthcare, pharmaceutical, medical device and food industries.

32 Westland Av Bolton, Greater Manchester, BL1 5NP United Kingdom

32 Westland Av Bolton, Greater Manchester, BL1 5NP United Kingdom

20A Cambridge Science Hub Cambridge, CB23 8SQ United KingdomAbbexa is based at the World renowned Cambridge Science Park, in Cambridge, UK. We are a supplier and distributor of biological tools for the life science, pharmaceutical development and biotechnology sectors. We provide the scientific community with primary antibodies, secondary antibodies, proteins, ELISA kits and enzymes as well as other kits and tools for use in research. Working with various laboratories across the World, we aim to develop relevant, high quality, tested products for the biomedical research market. Abbexa is a dedicated worldwide antibody supplier and protein supplier. Whether you are carrying out academic research, pharmaceutical research, disease research or other biological research, our monoclonal antibodies, polyclonal antibodies, proteins and biological reagents are designed to facilitate your research. We appreciate that sometimes it is hard to find the right antibody to match your needs, and we therefore offer a custom protein, peptide and antibody production pipeline. Abbexa is committed to providing scientists and researchers with the best customer experience and high quality products. We want to provide you with the best support available, which is why we guarantee customer satisfaction. If you are unhappy with the performance of your product we will offer you an immediate replacement or refund. Please have a look at our quality guarantee for further details. We are constantly striving to improve in everything we do, so please do get in touch with any comments regarding the website, service, products, or anything else.

181 Cambridge Science Park Cambridge, CB4 0GJ United KingdomAbbexa is based at the World renowned Cambridge Science Park, in Cambridge, UK. We are a supplier and distributor of biological tools for the life science, pharmaceutical development and biotechnology sectors. We provide the scientific community with primary antibodies, secondary antibodies, proteins, ELISA kits and enzymes as well as other kits and tools for use in research. Working with various laboratories across the World, we aim to develop relevant, high quality, tested products for the biomedical research market. Abbexa is a dedicated worldwide antibody supplier and protein supplier. Whether you are carrying out academic research, pharmaceutical research, disease research or other biological research, our monoclonal antibodies, polyclonal antibodies, proteins and biological reagents are designed to facilitate your research. We appreciate that sometimes it is hard to find the right antibody to match your needs, and we therefore offer a custom protein, peptide and antibody production pipeline. Abbexa is committed to providing scientists and researchers with the best customer experience and high quality products. We want to provide you with the best support available, which is why we guarantee customer satisfaction. If you are unhappy with the performance of your product we will offer you an immediate replacement or refund. Please have a look at our quality guarantee for further details. We are constantly striving to improve in everything we do, so please do get in touch with any comments regarding the website, service, products, or anything else.

Stobo House Edinburgh, UK, EH25 9RE United KingdomArrayjet Ltd is a leading Bioprinting & CRO/CMO providing innovative solutions to researchers, drug development groups and diagnostic companies world-wide. With significant microarraying experience and instrument installations in 28 countries globally, Arrayjet offers reliable consultative support and a well-proven technology. Whether printing onto slides, microplates or custom biochips, Arrayjet's platform uses unique, non-contact, inkjet printing to offer unrivalled throughput, precision, and consistency that delivers high quality, reproducible microarrays faster than any other technology. Through the provision of Arrayjet Advance in-house printing service, high-throughput screening programmes are possible: from examining host-pathogen interactions to epitope mapping, cancer and autoimmune biomarker identification, drug discovery, hybridoma screening and antibody validation. A range of five scaleable instruments are custom-built on-site, offering solutions from R&D through to full manufacturing capabilities.

Easter Bush Roslin Scotland, EH25 9RE United KingdomArrayjet Ltd is a leading Bioprinting & CRO/CMO providing innovative solutions to researchers, drug development groups and diagnostic companies world-wide. With significant microarraying experience and instrument installations in 28 countries globally, Arrayjet offers reliable consultative support and a well-proven technology. Whether printing onto slides, microplates or custom biochips, Arrayjet's platform uses unique, non-contact, inkjet printing to offer unrivalled throughput, precision, and consistency that delivers high quality, reproducible microarrays faster than any other technology. Through the provision of Arrayjet Advance in-house printing service, high-throughput screening programmes are possible: from examining host-pathogen interactions to epitope mapping, cancer and autoimmune biomarker identification, drug discovery, hybridoma screening and antibody validation. A range of five scaleable instruments are custom-built on-site, offering solutions from R&D through to full manufacturing capabilities.

40 Parham Drive Eastleigh Hampshire SO50 4NUAlpha Laboratories provides laboratory supplies, diagnostic kits and reagents, and bowel cancer test kits. Custom design services are also available for Pasteur pipettes, plate seals and UN3373 sample packaging - ideal for clinical trails packs.

40 Parham Drive Eastleigh Hampshire, SO50 4NU United KingdomAlpha Laboratories provides laboratory supplies, diagnostic kits and reagents, and bowel cancer test kits. Custom design services are also available for Pasteur pipettes, plate seals and UN3373 sample packaging - ideal for clinical trails packs.

Auchincruive KA6 5HW United KingdomAvantiCell Science Ltd (ACS) specialises in cell-based analysis using human primary and stem cells. ACS delivers cell-based services and cell products to a customer base spanning industry sectors, from pharmaceutical drug discovery through nutraceuticals and food development, to nanosafety testing. AvantiCell's unique expertise is in isolation of human primary cells from healthy or diseased tissues sourced as surgical excess with full ethical permission. Analytical platforms cover a wide range of tissues, including lung, kidney, vasculature, adipose, muscle, neural and digestive tract. The primary cell platforms are complemented by assays based around iPS-derived cells expressing tissue-specific differentiated phenotypes. AvantiCell has assembled technology for 3D culture of these cells, and for delivery of the cells as a pre-plated frozen product in multiwell plates.

GibbsYard Building Auchincruive Ayr Scotland KA6 5HW UKAvantiCell Science Ltd (ACS) specialises in cell-based analysis using human primary and stem cells. ACS delivers cell-based services and cell products to a customer base spanning industry sectors, from pharmaceutical drug discovery through nutraceuticals and food development, to nanosafety testing. AvantiCell's unique expertise is in isolation of human primary cells from healthy or diseased tissues sourced as surgical excess with full ethical permission. Analytical platforms cover a wide range of tissues, including lung, kidney, vasculature, adipose, muscle, neural and digestive tract. The primary cell platforms are complemented by assays based around iPS-derived cells expressing tissue-specific differentiated phenotypes. AvantiCell has assembled technology for 3D culture of these cells, and for delivery of the cells as a pre-plated frozen product in multiwell plates.

Gibbsyard Building Auchincruive, Ayr Scotland, KA6 5HW United KingdomAvantiCell Science Ltd (ACS) specialises in cell-based analysis using human primary and stem cells. ACS delivers cell-based services and cell products to a customer base spanning industry sectors, from pharmaceutical drug discovery through nutraceuticals and food development, to nanosafety testing. AvantiCell's unique expertise is in isolation of human primary cells from healthy or diseased tissues sourced as surgical excess with full ethical permission. Analytical platforms cover a wide range of tissues, including lung, kidney, vasculature, adipose, muscle, neural and digestive tract. The primary cell platforms are complemented by assays based around iPS-derived cells expressing tissue-specific differentiated phenotypes. AvantiCell has assembled technology for 3D culture of these cells, and for delivery of the cells as a pre-plated frozen product in multiwell plates.

Antibody Analytics Discovery Centre Braidhurst Industrial Estate, Newhut Road Motherwell, ML1 3ST United KingdomAt Antibody Analytics we believe that scientists deserve the best data, and patients deserve the best drugs. Led by a group of talented and engaged scientists, we look at biological problems in an openminded way to deliver beautifully designed, developed and qualified bioassays. We have developed a comprehensive portfolio of assays and platforms that can be tailored to support even the most complex of drug pipelines. Whether designing and developing bespoke bioassays or offering routine analysis on our already established assay platforms, Antibody Analytics has an exceptional track record of delivering beautiful results. We are primary cell experts and offer a range of off-the-shelf in vitro models or undertake custom projects, to meet your needs. Our key areas of expertise are tailored to the interrogation of bidning and function of antibodies, mAbs, bi- and multi-specifics, immune cell engagers, small molecules, immune cell modulators, antibody drug conjugates (ADCs), cell therapies and biosimilars. With expertise that we apply from target validation throughout lead identification, selection, characterisation and pre-clinical services. This includes cell line development capabilities to generate unique tools (target and reporter cells) for custom assay development, unique to your target and modality.

Bo'Ness Road Bo'ness Road Newhouse, Scotland, ML1 5UH United KingdomAt Antibody Analytics we believe that scientists deserve the best data, and patients deserve the best drugs. Led by a group of talented and engaged scientists, we look at biological problems in an openminded way to deliver beautifully designed, developed and qualified bioassays. We have developed a comprehensive portfolio of assays and platforms that can be tailored to support even the most complex of drug pipelines. Whether designing and developing bespoke bioassays or offering routine analysis on our already established assay platforms, Antibody Analytics has an exceptional track record of delivering beautiful results. We are primary cell experts and offer a range of off-the-shelf in vitro models or undertake custom projects, to meet your needs. Our key areas of expertise are tailored to the interrogation of bidning and function of antibodies, mAbs, bi- and multi-specifics, immune cell engagers, small molecules, immune cell modulators, antibody drug conjugates (ADCs), cell therapies and biosimilars. With expertise that we apply from target validation throughout lead identification, selection, characterisation and pre-clinical services. This includes cell line development capabilities to generate unique tools (target and reporter cells) for custom assay development, unique to your target and modality.

BioCity Scotland Bo'ness Road Newhouse , Lanarkshire, ML1 5UH United KingdomAt Antibody Analytics we believe that scientists deserve the best data, and patients deserve the best drugs. Led by a group of talented and engaged scientists, we look at biological problems in an openminded way to deliver beautifully designed, developed and qualified bioassays. We have developed a comprehensive portfolio of assays and platforms that can be tailored to support even the most complex of drug pipelines. Whether designing and developing bespoke bioassays or offering routine analysis on our already established assay platforms, Antibody Analytics has an exceptional track record of delivering beautiful results. We are primary cell experts and offer a range of off-the-shelf in vitro models or undertake custom projects, to meet your needs. Our key areas of expertise are tailored to the interrogation of bidning and function of antibodies, mAbs, bi- and multi-specifics, immune cell engagers, small molecules, immune cell modulators, antibody drug conjugates (ADCs), cell therapies and biosimilars. With expertise that we apply from target validation throughout lead identification, selection, characterisation and pre-clinical services. This includes cell line development capabilities to generate unique tools (target and reporter cells) for custom assay development, unique to your target and modality.

Catherine Bladen Wilton Centre Redcar, Cleveland , TS10 4RF United Kingdom-Absolute Antibody specialises in the sequencing, engineering and recombinant production of antibodies. We offer antibody sequencing from cell lines such as hybridomas or immortalised B-cells as well as sequencing from purified antibody protein. Our engineering services include species/isotype switching, full humanization, generation of custom bispecifics, Fabs, Fc fusions and more! If you can describe it, we can make it. Using our serum-free transient expression platform we cater for milligram to gram scales with delivery in as little as 3 weeks. All of our services are royalty free. -We also have a catalog of recombinant reagents, including antibodies against common immune checkpoints, viruses and a range of research-grade biosimilars. All are available in any species and any isotype to suit your assay. -We're always excited to hear about new ideas, exciting innovations, and potential collaborations. Challenge us with your antibody problems - we'll see what we can do.

Wilton Centre Lazenby Drive Redcar, TS104RF United Kingdom-Absolute Antibody specialises in the sequencing, engineering and recombinant production of antibodies. We offer antibody sequencing from cell lines such as hybridomas or immortalised B-cells as well as sequencing from purified antibody protein. Our engineering services include species/isotype switching, full humanization, generation of custom bispecifics, Fabs, Fc fusions and more! If you can describe it, we can make it. Using our serum-free transient expression platform we cater for milligram to gram scales with delivery in as little as 3 weeks. All of our services are royalty free. -We also have a catalog of recombinant reagents, including antibodies against common immune checkpoints, viruses and a range of research-grade biosimilars. All are available in any species and any isotype to suit your assay. -We're always excited to hear about new ideas, exciting innovations, and potential collaborations. Challenge us with your antibody problems - we'll see what we can do.

Lacon House 84 Theobalds Road London, WC1X 8NL United KingdomAcaster Lloyd Consulting Ltd provides consulting services around clinical outcomes assessments, patient reported outcomes and other subjective self report measures used in the assessment of the impact of disease and treatments on patients lives.

Lacon House 84 Theobalds Road London, WC1X 8NL United KingdomAcaster Lloyd Consulting Ltd provides consulting services around clinical outcomes assessments, patient reported outcomes and other subjective self report measures used in the assessment of the impact of disease and treatments on patients lives.

16 Upper Woburn Place London, WC1H 0BS United KingdomAcaster Lloyd Consulting Ltd provides consulting services around clinical outcomes assessments, patient reported outcomes and other subjective self report measures used in the assessment of the impact of disease and treatments on patients lives.

APC, Cromwell Office Park, York Road, Wetherby, LS22 7SU, UNITED KINGDOMAPC helps biopharma companies slash drug development times by delivering breakthrough science at lightning fast process development speed. We thrive on radical collaboration, challenging ourselves and our clients to deliver for patients faster. *Breakthrough Science* We are process development experts – chemical and bioprocess engineers, organic and process chemists, statisticians, analysts, and project managers – who live to create better processes, build newer technology, and solve CMC problems that others shy away from. Our breakthroughs power pipelines and take CMC off the critical path. We work across modalities, from synthetics to cell and gene therapies, using world class process research, engineering and modelling to deliver the breakthroughs our clients once thought impossible. *Lightning Fast Development* Our singular objective is to be the best process development organization in the world, because to go fast you need focus. APC’s projects and partnerships deliver more CMC outcomes per unit time than anyone else and our technology platforms are changing the paradigm for speed in process development. We leave manufacturing to others; instead, we push our clients to broaden their CMO network, take control of their manufacturing strategy, and eliminate rework and failures from clinical and commercial supply. APC processes deliver right-first-time performance across the product lifecycle meaning our clients never slow down on the journey to their patients. *Radical Collaboration* We ask before we tell – and we strive for every client conversation to be more transparent and patient-focused than the last. We know that our clients are knowledge powerhouses and we constantly ask great questions designed to unlock that key insight that will propel a medicine from molecule to market faster. Our clients are on a mission to save lives. We help them. Website http://www.approcess.com

20 Seagoe Road 19 Seagoe Industrial Estate Craigavon, BT63 5QD United KingdomThe Almac Group is an established contract development and manufacturing organisation providing an extensive range of integrated services across the drug development lifecycle to the pharmaceutical and biotech sectors globally. Our innovative services range from R&D, biomarker discovery development and commercialisation, API manufacture, formulation development, clinical trial supply, IRT (IVRS/IWRS) through to commercial-scale manufacture, packaging & globally distribution. The international company is a privately owned organisation that has grown organically over the past five decades now employing over 6,600 highly skilled personnel across 18 facilities including Europe, the US and Asia.

20 Seagoe Industrial Estate Craigavon, BT63 5QD United KingdomThe Almac Group is an established contract development and manufacturing organisation providing an extensive range of integrated services across the drug development lifecycle to the pharmaceutical and biotech sectors globally. Our innovative services range from R&D, biomarker discovery development and commercialisation, API manufacture, formulation development, clinical trial supply, IRT (IVRS/IWRS) through to commercial-scale manufacture, packaging & globally distribution. The international company is a privately owned organisation that has grown organically over the past five decades now employing over 6,600 highly skilled personnel across 18 facilities including Europe, the US and Asia.

120E Olympic Avenue, Milton Park Abingdon, Oxfordshire, OX14 4SA United KingdomArctoris is the world’s first fully automated drug discovery platform, enabling pharmaceutical corporations, biotech companies and academic centres to configure, run and monitor experiments in real-time at Arctoris’ robotic laboratory facility. Arctoris thereby offers a powerful platform for basic biology, target validation, toxicology and phenotypic screening, combining the latest in cellular and molecular techniques and instrumentation with advanced robotics and access to online analytical software, data visualisation & secure cloud storage. Arctoris creates a convincing solution for fast, reliable and fully compliant research, bringing drug discovery into the digital age.

Stirling, Scotland FK9 4LA United KingdomAquatic Diagnostics develops and markets monoclonal antibodies and antibody conjugates.

The Magdalen Centre Oxford Science Park Oxfordshire, OX44GA, UKAngiogene Pharmaceuticals offers compound development for the preclinical stage.

England United KingdomAngiogene Pharmaceuticals offers compound development for the preclinical stage.

Unit 67 Listerhills Science Park, Campus Road Bradford, BD7 1HR United KingdomAgenda1 Analytical Services offers chromatography, physical analysis, microbiology, and formulation assessment services.

Bradford, England United KingdomAgenda1 Analytical Services offers chromatography, physical analysis, microbiology, and formulation assessment services.

Building 5 Chiswick Park 566 Chiswick High Road London W4 5YFAntisoma focuses on the development of novel drugs for the treatment of cancer.

Buckingham Place, Church Road, Penn Buckinghamshire, HP10 8LN, UKAgropharm was established in 1974 with the objective of providing pest control products that meet customer needs. Since that time the company has grown and developed a range of strong brands and innovative products. The focus is on eco-friendly products designed for powerful pest control with minimum impact on the environment. Agropharm develops and manufactures its own products at its production centre in Telford, Shropshire and is managed from the Head Office in High Wycombe, Buckinghamshire. The facilities include a well equipped analytical and formulation laboratory, product bottling lines, powder handling and many other facilities. Agropharm’s technical staff are highly qualified and have a track record of developing new formulations and innovative products. Many of these products are developed specially for our customer’s own brands. This success is based on a genuine interest in listening to our customer’s needs and ideas and developing strong, lasting partnerships that are beneficial to both parties. Agropharm is also an award winning company having won the prestigious Buckinghamshire International Trade Award in 2007 and the Innovation & Enterprise Award in 2008. These awards recognised Agropharm’s achievement in the export markets and its excellence in product development.

UK Office Regus House, Highbridge, Oxford Road Uxbridge UB81HRAbdi İbrahim provides pharmaceutical services to the healthcare sector.

Ryhall Road Stamford Lincolnshire PE9 1TZ United KingdomFounded in 1980 by Irish biochemist and entrepreneur Dr. Pearse Lyons, Alltech is a leading global biotechnology company whose mission is to improve the health and performance of people, animals and plants through natural nutrition and scientific innovation. We pursue this mission guided by what we call the ACE principle, our promise that in doing business we have a positive impact on the Animal, the Consumer and the Environment. Animal Health Our core business improves animal health and performance by adding nutritional value to feed, naturally, through Alltech’s innovative use of yeast fermentation, enzyme technology, algae and nutrigenomics, which studies the impact of nutrition at the genetic level. Our technologies and support programs enable farmers to realize greater efficiency, profitability and sustainability on their farms. Alltech Crop Science Our Alltech Crop Science division complements our animal nutrition business by focusing on improving the health of crops. Our technologies enable us to improve the productivity of the field, in terms of yield quality and quantity, and to enhance nutrition beginning with the soil and the seed. Human Health We believe scientific innovation in animal and crop sciences is part of a much more important story, that of human health. Healthier animals and crops, nurtured naturally through Alltech’s nutritional solutions, affect human well-being. For example, fruits, vegetables and animal proteins have become less nutrient-rich in the past half-century. From fish to oranges, you need to eat more today to get the same nutritional value. Our work within animal and crop sciences is restoring value and also exploring ways to naturally enrich foods through improving the animal diet or crop produced. For example, laying hens fed a diet rich in Alltech’s algae produce eggs enriched with DHA omega-3, an essential nutrient for human cognitive development and health at all ages.

1010 Cambourne Business Park Cambourne Cambridge CB23 6DP UKAbcodia is a clinical stage company engaged in the commercial development of novel, scientifically validated tests for the early detection of cancer. The Company's first product is the ROCA® Test for the early detection of ovarian cancer. It is also expanding its pipeline of early detection technologies for lung, colorectal and pancreatic cancer. Our products are based on expertise in measuring and modelling dynamic changes over time of serum-based biomarkers before cancer is clinically diagnosed and it maintains exclusive commercial access to a biobank of prospectively collected samples donated from over 200,000 individuals over a 10-year period. We hold strategic collaborations with leading global organizations including Cancer Research UK, University College London and other academic and industry partners. Abcodia is a privately held company funded through investments from Albion Ventures, Cambridge Innovative Capital plc, Scottish Equity Partners and UCL Business Plc. Headquartered in Cambridge, U.K., the Company maintains a U.S. corporate presence in Boston.

21 Albemarle Street, London, W1S 4BS United KingdomApta Biosciences is a synthetic biology company specialised in developing unique, proprietary molecules that can be used broadly across diagnostics & therapeutics to facilitate and expand scientific discovery enabling the development of new healthcare solutions.

1 Hamden Way Papworth Everard Cambridgeshire CB23 3UG United KingdomAnthias Consulting provides consulting for gas chromatography, scientific instrumentation, and training.

7 Bennell Court West Street Comberton Cambridge CB23 7EN UKActivotec offers custom peptide synthesis, and peptide therapeutics.

Abcellute Ltd BioPark Braodwater Road Welwyn Garden City Herts AL7 3AXAbcellute prvodies SureTran cell transport technology for pre-clinical drug evaluation and regenerative medicine.

Arnold Consultancy & Technology 1 Penn Plaza - 36th Floor New York, NY 10001At Arnold Consultancy and Technology LLC our area of expertise is outcomes research in all therapeutic categories and we develop interactive models and software related to cost-effectiveness analysis, pricing, and adverse event reporting/pharmacovigilance.

Commerce Way Edenbridge Kent TN8 6ED United KingdomAmbe Medical offers distribution and logistics of pharmaceutical products.

Leatherhead, England United KingdomAROXA™ provides more than 250 certified flavour standards which can be used to test the aptitude of potential new tasters; develop the skills they need; and assess their day to day performance in routine tasting.

18-20 High Street Shaftesbury, Dorset, SP7 8JG United KingdomApis BBI has considerable experience in the major therapeutic areas, including Oncology, Cardiovascular, CNS/Neurosciences, Respiratory/Pulmonary, Rheumatology/Arthritis and Diabetes as well as in cell biology, virology and bacteriology. We are widely known for human tissue banking and associated technologies such as microscopy, the application of TMAs and affinity probing technologies.

a-connect solution (uk) limited 3rd Floor, 12 Gough Square London, EC4A 3DW United Kingdom

Bachem (UK) Ltd. Delph Court Sullivans Way, St. Helens Merseyside WA9 5GL EnglandBachem offers custom peptide synthesis and GMP peptide manufacturing services, including process development, scale-up production, analytical and process validation and stability studies.

Halton House, 20-23 Holborn, London EC1N 2JD UKAnalytica LASER is a scientific consultancy that specialises in Real World Data, Analytics and HEOR and Market Access services. A significant portion of this work involves developing rigorous, evidence-based materials to help guide research and healthcare decisions. Our international team is a diverse group of experts with a breadth of experience, including high level (MSc and PhD) researchers, former payers, pharmaceutical industry leaders, noted academics, and highly experienced industry consultants. Our diverse scientific team includes statisticians, epidemiologists, mathematicians, economists, physicians, pharmacists and other pertinent expertise that assures the development of scientifically rigorous, insightful and actionable deliverables for our customers. PGRx Real World Datasets are targeted case registries that operate in multiple disease areas. PGRx provides quality data for most real world studies required by our HEOR and market access clients such as burden of illness, treatment patterns, drug utilisation, health resource use and quality of life studies. Programs for new pathologies can be rapidly deployed as a result of the validated protocol/tools and the extensive network of specialists created over the years that PGRx has been operating. PGRx uniquely links detailed medical data and HRU information from the physician with extensive patient-reported data on drug usage, adherence, quality of life and productivity impact. This gives a rich source of ‘deep’ data on patients, their management, possible drivers of effectiveness and the associated patient outcomes. Our other Real World Data solutions services include electronic database analytics, chart reviews, patient/physician surveys and advanced outcomes research and pharmacoepidemiology studies. Analytica LASER has been at the forefront of advising clients on market access issues with strategic consultancy, development of global value dossiers, evidence synthesis amongst other services.

5th Floor Front, Audrey House 16-20 Ely Place London EC1N 6SN United KingdomAnalytica LASER is a scientific consultancy that specialises in Real World Data, Analytics and HEOR and Market Access services. A significant portion of this work involves developing rigorous, evidence-based materials to help guide research and healthcare decisions. Our international team is a diverse group of experts with a breadth of experience, including high level (MSc and PhD) researchers, former payers, pharmaceutical industry leaders, noted academics, and highly experienced industry consultants. Our diverse scientific team includes statisticians, epidemiologists, mathematicians, economists, physicians, pharmacists and other pertinent expertise that assures the development of scientifically rigorous, insightful and actionable deliverables for our customers. PGRx Real World Datasets are targeted case registries that operate in multiple disease areas. PGRx provides quality data for most real world studies required by our HEOR and market access clients such as burden of illness, treatment patterns, drug utilisation, health resource use and quality of life studies. Programs for new pathologies can be rapidly deployed as a result of the validated protocol/tools and the extensive network of specialists created over the years that PGRx has been operating. PGRx uniquely links detailed medical data and HRU information from the physician with extensive patient-reported data on drug usage, adherence, quality of life and productivity impact. This gives a rich source of ‘deep’ data on patients, their management, possible drivers of effectiveness and the associated patient outcomes. Our other Real World Data solutions services include electronic database analytics, chart reviews, patient/physician surveys and advanced outcomes research and pharmacoepidemiology studies. Analytica LASER has been at the forefront of advising clients on market access issues with strategic consultancy, development of global value dossiers, evidence synthesis amongst other services.

Sands Mill, Huddersfield Road, Mirfield, West Yorkshire WF14 9DQ, United KingdomALS Food and Pharmaceutical is one of the UK’s leading providers of food testing and drink testing services. We have over 20 years experience of offering a range of high quality analytical testing services across the UK and Ireland through our UKAS accredited laboratories.

England United KingdomATDBio offers oligo synthesis services.

19G Mereside Alderley Park Macclesfield, SK10 4TG United KingdomImmundnz, together with its sister company Abundnz, offers advanced in vitro, immunology and (bio)analytical support for biotechnology and diagnostics industries and life sciences research worldwide. A range of solutions are available to our clients. Our services include preclinical immunology research, in vitro research and the characterization and bioanalysis of innovative medicines such as peptide and protein drugs, oligonucleotides and nanomedicines. Due to our experience and track record, you can rely on us as your solid partner in in vitro, immunology and (bio)analytical support for your projects.

England, LS23 7GA United KingdomAvacta Analytical recognizes and supports market leaders’ drive for “smaller, faster, better” with pioneering and innovative analytical instrumentation.

Block 3F68, Mereside SK10 4TG United KingdomApconiX™ is an integrated toxicology and ion channel company at the forefront of innovative thinking in nonclinical toxicology and safety science. Experts in cardiac safety data delivery and interpretation Experts in target safety assessment High-quality CiPA ion channel assays (hERG, hNaV1.5, hCaV1.2, hKir2.1, Iks, Ito). Expert advice on how to interpret the data in the context of your programme, and what to do next. Provide on-hand advice on assay conditions, protocols and technologies. Bespoke assay development and screening for all ion channel targets. Conventional patch-clamp, Patchliner and IonWorks Quattro platforms.

Alderley Park Alderley Edge Cheshire, SK10 4TG United KingdomApconiX™ is an integrated toxicology and ion channel company at the forefront of innovative thinking in nonclinical toxicology and safety science. Experts in cardiac safety data delivery and interpretation Experts in target safety assessment High-quality CiPA ion channel assays (hERG, hNaV1.5, hCaV1.2, hKir2.1, Iks, Ito). Expert advice on how to interpret the data in the context of your programme, and what to do next. Provide on-hand advice on assay conditions, protocols and technologies. Bespoke assay development and screening for all ion channel targets. Conventional patch-clamp, Patchliner and IonWorks Quattro platforms.

Devonshire House, 582 Honeypot Lane Middlesex Stanmore, Middlesex, HA71JS United KingdomAcellera is devoted to bringing state-of-the-art technologies to drug discovery. Founded in 2006, we were one of the first companies worldwide to leverage the use of novel accelerator processor technology (GPU) for molecular dynamics. We developed the first online platform for drug design based on deep learning and are now leading the introduction of machine learning techniques into the drug discovery pipeline.

Steanard Ln Mirfield, W14 8HZ United KingdomAurigene Pharmaceutical Services is a leading contract research, development and manufacturing organization (CDMO) that provides a range of services. Built on the legacy of accelerating innovation and backed by a vast experience in integrated drug discovery, development and manufacturing services, we provide access to our knowledge, resources, capability and experience, creating shared success for our clients and ultimately patients. Our service Offerings: 1. Discovery Chemistry - Medicinal Chemistry - Synthetic Chemistry - Library Synthesis - Peptide Synthesis - Analytical Chemistry - Carbohydrates Chemistry 2. Discovery Biology - In-Vitro Biology - ADME/PK Microbiology - In-Vivo Pharmacology - Pre-clinical Safety Evaluation (toxicology) -Antibody discovery -Protein expression -Antibody development -Fusion protein -Protein structure determination -ADC -mRNA -CAR-T 3. Chemical Development - Process Design - Development and Optimization - Route Scouting - Analytical Method Development and Validation - Polymorph Screening - Material Generation - Scale-up and Troubleshooting - Stability Studies 4. Formulation development services - Pre-clinical Formulations (Solutions, Suspensions & Microdose Capsules) - First in human formulations (Oral Solids, Liquids, Ophthalmic Solutions, Nasal Solutions & Injections) - Clinical formulations (Oral Solids, Liquids, Ophthalmic Solutions, Nasal Solutions & Injections) 5. Manufacturing Services a. Drug Subtance - Small molecules - HPAPI - Peptides - Carbohydrates - Steroids -mAbs -Fusion proteins b. Drug Products - Oral Dosage Form (tablets, capsules, oral liquids & phase appropriate formulation) - Parenteral Dosage (conventional & lyophilized) - Topical Dosage (solutions, lotions, ointments, gels & creams) c. Specialized - Complex Key Starting Material (KSM), Registered Starting Material (RSM) and Advanced Intermediates - Activated m-PEGs - Ligands and Catalysts

Steanard Ln Mirfield, W14 8HZ United KingdomAurigene Pharmaceutical Services is a leading contract research, development and manufacturing organization (CDMO) that provides a range of services. Built on the legacy of accelerating innovation and backed by a vast experience in integrated drug discovery, development and manufacturing services, we provide access to our knowledge, resources, capability and experience, creating shared success for our clients and ultimately patients. Our service Offerings: 1. Discovery Chemistry - Medicinal Chemistry - Synthetic Chemistry - Library Synthesis - Peptide Synthesis - Analytical Chemistry - Carbohydrates Chemistry 2. Discovery Biology - In-Vitro Biology - ADME/PK Microbiology - In-Vivo Pharmacology - Pre-clinical Safety Evaluation (toxicology) -Antibody discovery -Protein expression -Antibody development -Fusion protein -Protein structure determination -ADC -mRNA -CAR-T 3. Chemical Development - Process Design - Development and Optimization - Route Scouting - Analytical Method Development and Validation - Polymorph Screening - Material Generation - Scale-up and Troubleshooting - Stability Studies 4. Formulation development services - Pre-clinical Formulations (Solutions, Suspensions & Microdose Capsules) - First in human formulations (Oral Solids, Liquids, Ophthalmic Solutions, Nasal Solutions & Injections) - Clinical formulations (Oral Solids, Liquids, Ophthalmic Solutions, Nasal Solutions & Injections) 5. Manufacturing Services a. Drug Subtance - Small molecules - HPAPI - Peptides - Carbohydrates - Steroids -mAbs -Fusion proteins b. Drug Products - Oral Dosage Form (tablets, capsules, oral liquids & phase appropriate formulation) - Parenteral Dosage (conventional & lyophilized) - Topical Dosage (solutions, lotions, ointments, gels & creams) c. Specialized - Complex Key Starting Material (KSM), Registered Starting Material (RSM) and Advanced Intermediates - Activated m-PEGs - Ligands and Catalysts

Adelphi Mill, Bollington Cheshire, SK10 5JB, UKAdelphi Real World : Experts in the generation of real-world data and shaping of real-world evidence Conducting multi-country real-world observational studies and healthcare database analyses for over 25 years, our services are grounded in the extensive heritage afforded by Adelphi’s proprietary Disease Specific Programmes™ and supported by the subsequent expansion of our real-world evidence services to meet pharmaceutical client needs. We provide a unique range of real-world insights involving physicians, patients, caregivers and payers; with insights achieved through our market-leading Disease Specific Programmes™, tailored non-interventional studies, international secondary database analyses and expert market access strategy. Adelphi Real World is a dedicated team of more than 200 professionals; we provide support and guidance for our clients across all areas of real-world evidence implementation. Our scope of work and experience covers the complete lifecycle of a compound. Our global coverage ensures our evidence can shape all levels of insight from multi-country strategy through to domestic, tactical implementation.

Grimshaw Lane Grimshaw Lane Bollington, England, SK10 5JB United KingdomAdelphi Real World : Experts in the generation of real-world data and shaping of real-world evidence Conducting multi-country real-world observational studies and healthcare database analyses for over 25 years, our services are grounded in the extensive heritage afforded by Adelphi’s proprietary Disease Specific Programmes™ and supported by the subsequent expansion of our real-world evidence services to meet pharmaceutical client needs. We provide a unique range of real-world insights involving physicians, patients, caregivers and payers; with insights achieved through our market-leading Disease Specific Programmes™, tailored non-interventional studies, international secondary database analyses and expert market access strategy. Adelphi Real World is a dedicated team of more than 200 professionals; we provide support and guidance for our clients across all areas of real-world evidence implementation. Our scope of work and experience covers the complete lifecycle of a compound. Our global coverage ensures our evidence can shape all levels of insight from multi-country strategy through to domestic, tactical implementation.

Whitefield Rd, Bredbury, Stockport, Cheshire, SK6 2QRApollo provides custom organic synthesis in gram to commercial quantities.

Whitefield Rd, Bredbury Stockport, Cheshire, SK6 2QR United KingdomApollo provides custom organic synthesis in gram to commercial quantities.

19 Barton Ln Abingdon Science Park Abingdon, Oxfordshire, OX14 3NB United KingdomA Bio-techne brand based in Silicon Valley, ACD’s products and Pharma Assay Services are based on its proprietary RNAscope® technology, the first multiplex fluorescent and chromogenic in situ hybridization platform, capable of detecting and quantifying single molecules of RNA in situ. ACD has two product lines, namely RNAscope® and BaseScope™ consisting of assay reagent kits and 15,000+ off-the-shelf probes in addition to a Pharma Assay Services business which allow customers to run assays for their unique targets rapidly. Since its first launch in 2011, the technology boasts 1500+ citations, a new publication each day now, for single, duplex and multiplex RNA analysis. The company’s technology overcomes critical hurdles in the identification and validation of biomarkers for companion diagnostics. ACD’s RNAscope® platform provides a new way of localizing and measuring RNA in situ with exceptional levels of sensitivity, specificity, and the ability to multiplex. Turnaround time for a new assay is reduced to 2-3 weeks. These advantages make the technology a powerful tool to address the issue of patient and disease heterogeneity, thus shortening the path to personalized medicine. Through ACD's Pharma Assay Services, tissue sectioning, ISH staining, high resolution full slide scanning, scoring, and image analysis are performed by a dedicated team of highly trained specialists, scientists, and board-certified pathologists. With direct access to the developers of the technology, PAS provides unparalleled expertise in ACD’s ISH platforms and delivers fast, high quality data designed to meet your study objectives and timelines.

NUBI, Medical School Framlington Place Newcastle Upon Tyne, Tyne and Wear, NE2 4HH United KingdomAelius Biotech specialise in lab models of the aerodigestive tract. Our predictive systems can help you understand your formulation during vital pre-clinical stages to help you improve and de-risk product development and get successful products to market.

Unit A Stratton View Business Park Stratton Bude, Cornwall EX23 9NR United KingdomAtlantic Research Chemicals is a supplier of speciality building blocks and intermediates to the pharmaceutical, biotechnology and agrochemical industry.

Unit A/Stratton View Business Park Bude, EX23 9NR United KingdomAtlantic Research Chemicals is a supplier of speciality building blocks and intermediates to the pharmaceutical, biotechnology and agrochemical industry.

Spring Lodge, 172 Chester Road Helsby, WA6 0AR United KingdomADAS delivers a wide range of consultancy, research and training in relation to the health and welfare of all major livestock species (including cattle, sheep, pigs and poultry), working to improve stock performance, ensure consumer needs are met and enhance industry reputation. Specialist livestock consultants work with farmers, policy-makers, retailers and others to provide practical information and advice on animal health and welfare. We combine commercial and scientific expertise with knowledge of legislation and emerging issues to assess the impacts of policy options for Government. We carry out animal health benchmarking, typically based on groups using a ‘focus farm’ approach. We also establish and monitor Key Welfare Indicators (KWIs) for different livestock sectors and use these activities as a basis for advising on changes and improvements. We help our clients to design and monitor their own farm trials and we also have our own livestock research facility which we use to undertake more detailed studies for clients. Our consultants provide livestock health and welfare training events for experienced managers and trainees, government policy-makers, inspectors and veterinarians. We undertake a wide range of stakeholder consultations and knowledge transfer activities in relation to current livestock health issues. This includes organising, facilitating and speaking at meetings and focus groups, providing information to farmers and policy-makers alike. Our livestock consultants also work outside of the UK, both in other EU Member States and third countries, delivering short-term animal-health related consultancy projects and contributing to research work.

Newforge Lane, Belfast UKThe Agri-Food & Biosciences Institute (AFBI) was created on 1st April 2006 as an amalgamation of the Department of Agriculture and Rural Development (DARD) Science Service and the Agricultural Research Institute of Northern Ireland (ARINI). AFBI is a DARD Non-Departmental Public Body (NDPB). AFBI carries out high technology research and development, statutory, analytical, and diagnostic testing functions for DARD and other Government departments, public bodies and commercial companies.. AFBI's NDPB status enables it to be innovative and entrepreneurial in its approach to business development. AFBI is forging new partnerships with other scientific institutes and research organisations and extending the range of services it offers. This enables AFBI’s unique breadth of scientific capabilities in the areas of agriculture, animal health, food, environment and biosciences to be offered to a wider prospective national and international customer base. AFBI is managed by an independent Board which is also responsible for monitoring its performance.

68 A Love Lane Burnham-On-Sea TA8 1EY

68 Love Lane Burnham-on-Sea, England, TA8 1EY United Kingdom

AssayMetrics Limited 22 Angelica Way Cardiff CF14 9FJ UNITED KINGDOMAssayMetrics provides fluorescent dyes, kinase assays, caspase assays, and labeling reagents.

Cardiff, Wales United KingdomAssayMetrics provides fluorescent dyes, kinase assays, caspase assays, and labeling reagents.

Suite 2.80 – 2.87 Bio Centre Innovation Way Heslington, York, YO10 5NY United KingdomOur proprietary high-throughput aptamer selection processes allows us to offer a flexible and competitive pricing structure for the development of RNA and DNA aptamers. Depending on the number of targets required, and type of target in question, we can offer aptamer selections for a very competitive price. Our automated process allows us to develop many aptamers simultaneously meaning that we can offer faster speed of production and a reduced cost per-aptamer. We can supply the developed aptamers in ng, µg, mg, and or kg quantities if required. We can also supply aptamers with a range of functionalization chemistries attached.

Arden Tissue Bank, Pathology Department, University Hospitals Coventry & Warwickshire NHS Trust, Binley, Coventry, CV2 2DXArden Tissue Bank, which is based at University Hospital Coventry, aims to provide researchers with access to a diverse range of high quality human tissue, whilst complying with national legislation. Arden Tissue Bank stores routine surgical tissues that have been taken for diagnosis. Once diagnosis has been established, this tissue is normally discarded and destroyed.

Colworth Science Park Iselworth Building Sharnbrook, Bedfordshire MK44 1LQ United KingdomAME Bioscience supplies laboratory equipment and instruments.

Sharnbrook, England, MK44 United KingdomAME Bioscience supplies laboratory equipment and instruments.

2 Cambridge Science Park, Cambridge, CB4 0FE, United KingdomArecor offers protein stabilization technology, protein formulation, manufacturing, and regulatory affairs.

Winch Road Kent Science Park Sittingbourne England, ME9 8EF United KingdomAt AbBaltis we serve the In Vitro Diagnostics and Biotech markets by offering innovative, reliable and quality biologically-based products for our clients. Our purpose is to supply a wide variety of disease state plasma and residual clinical samples with: Fast Delivery around the Globe Competitive Pricing Outstanding Customer Support We have a passion to improve the lives of patients by focusing on innovations that deliver the highest quality research and the most beneficial products. With a seasoned team of scientists and researchers, AbBaltis brings together leaders with industry experience in assay development, diagnostic research and new market development. Additionally, we know that scientific enterprise brings many challenges so our staff will help you to overcome those challenges by understanding your priorities and delivering a personalized service. Therefore, please do not hesitate to contact us to discover why we are an award winning company.

1020 Innovation Building Kent Science Park Sittingbourne, Kent, ME98HL United KingdomAt AbBaltis we serve the In Vitro Diagnostics and Biotech markets by offering innovative, reliable and quality biologically-based products for our clients. Our purpose is to supply a wide variety of disease state plasma and residual clinical samples with: Fast Delivery around the Globe Competitive Pricing Outstanding Customer Support We have a passion to improve the lives of patients by focusing on innovations that deliver the highest quality research and the most beneficial products. With a seasoned team of scientists and researchers, AbBaltis brings together leaders with industry experience in assay development, diagnostic research and new market development. Additionally, we know that scientific enterprise brings many challenges so our staff will help you to overcome those challenges by understanding your priorities and delivering a personalized service. Therefore, please do not hesitate to contact us to discover why we are an award winning company.

Alderley Park Alderley Edge Macclesfield, Cheshire, SK104TG United KingdomAlderley Analytical is an independent Contract Research Organisation (CRO) offering bioanalytical services to support your drug development programmes, from discovery through to late stage clinical development, focusing on small molecules, large molecules, peptides, biologics and biomarkers. We are GLP and GCP compliant and therefore in addition to supporting your discovery programmes we can support your regulatory packages including GLP safety studies and clinical projects.

BioHub at Alderley Park Alderley Edge Macclesfield Cheshire UK SK10 4TGAlderley Analytical is an independent Contract Research Organisation (CRO) offering bioanalytical services to support your drug development programmes, from discovery through to late stage clinical development, focusing on small molecules, large molecules, peptides, biologics and biomarkers. We are GLP and GCP compliant and therefore in addition to supporting your discovery programmes we can support your regulatory packages including GLP safety studies and clinical projects.

BioHub at Alderley Park Alderley Edge Macclesfield Cheshire SK10 4TG UKAlderley Analytical is an independent Contract Research Organisation (CRO) offering bioanalytical services to support your drug development programmes, from discovery through to late stage clinical development, focusing on small molecules, large molecules, peptides, biologics and biomarkers. We are GLP and GCP compliant and therefore in addition to supporting your discovery programmes we can support your regulatory packages including GLP safety studies and clinical projects.

Pennyfoot Street Pennyfoot Street England, NG1 1GF United KingdomAurelia Bioscience offers lab-based services in bio-assay development and screening for small molecules and biologics using state of the art technologies applied to cell-based and biochemical assays. Technologies in our laboratory include: FLIPR Tetra, a fluorescence kinetic microplate reader and dispenser used for imaging intra-cellular calcium or potassium movement following ligand addition. FMAT, or Fluorescence MicroAssay Technology, a quasi con-focal plate reader, able to identify objects (beads and cells) in wells and measure the fluorescence in close proximity to the object whilst ignoring the surrounding fluorescence - used for cell and bead based binding studies. EnSpire label free, a technology developed by Corning Inc that uses specialised glass bottom microwell plates to image dynamic mass re-distribution of proteins in the membrane and proximal to the cytoplasm following ligand addition without the need for dyes or incorporation of cDNA. Guava FlowCyte, a flow cytometry system used to examine populations of cells in solution following treatment and labelling with fluorescence dyes. EnVision, a highly sensitive plate reader that can be used for both fluorescence and luminescence assays. Cellomics CX5 high content imager, able to examine both kinetic and fixed cell end point assays using imaging technology with fluorescently labelled antibodies or proteins at a number of magnifications. QuantiStudio 6 HT qPCR reader, able to detect mRNA changes in samples from cells in 384 well format. WES from Protein Simple, a system designed to perform high throughput Western Blot analysis to detect changes in specific proteins secreted from cells. All of the above can be applied to your biology of interest. Aurelia Bioscience are agnostic to disease area, we bring our technological know how to bear on to your biological questions and hopefully shed light on the mechanisms and identify compounds that interact with your target to, one day, be a future medicine. Previous diseases areas we have worked in include respiratory and inflammatory disease, oncology and cancer biology including hypoixia, muscule wasting disorders, cardiovascular disease and metabolic disorders. In addition we have our own 3-D biology R&D project, examining the biology of recombinant cells, primary cells and stem cells in an unique proprietary electrospun scaffold matrix for screening compounds and biologics.

Pennyfoot Street Pennyfoot Street England, NG1 1GF United KingdomAurelia Bioscience offers lab-based services in bio-assay development and screening for small molecules and biologics using state of the art technologies applied to cell-based and biochemical assays. Technologies in our laboratory include: FLIPR Tetra, a fluorescence kinetic microplate reader and dispenser used for imaging intra-cellular calcium or potassium movement following ligand addition. FMAT, or Fluorescence MicroAssay Technology, a quasi con-focal plate reader, able to identify objects (beads and cells) in wells and measure the fluorescence in close proximity to the object whilst ignoring the surrounding fluorescence - used for cell and bead based binding studies. EnSpire label free, a technology developed by Corning Inc that uses specialised glass bottom microwell plates to image dynamic mass re-distribution of proteins in the membrane and proximal to the cytoplasm following ligand addition without the need for dyes or incorporation of cDNA. Guava FlowCyte, a flow cytometry system used to examine populations of cells in solution following treatment and labelling with fluorescence dyes. EnVision, a highly sensitive plate reader that can be used for both fluorescence and luminescence assays. Cellomics CX5 high content imager, able to examine both kinetic and fixed cell end point assays using imaging technology with fluorescently labelled antibodies or proteins at a number of magnifications. QuantiStudio 6 HT qPCR reader, able to detect mRNA changes in samples from cells in 384 well format. WES from Protein Simple, a system designed to perform high throughput Western Blot analysis to detect changes in specific proteins secreted from cells. All of the above can be applied to your biology of interest. Aurelia Bioscience are agnostic to disease area, we bring our technological know how to bear on to your biological questions and hopefully shed light on the mechanisms and identify compounds that interact with your target to, one day, be a future medicine. Previous diseases areas we have worked in include respiratory and inflammatory disease, oncology and cancer biology including hypoixia, muscule wasting disorders, cardiovascular disease and metabolic disorders. In addition we have our own 3-D biology R&D project, examining the biology of recombinant cells, primary cells and stem cells in an unique proprietary electrospun scaffold matrix for screening compounds and biologics.

Biocity Pennyfoot Street Nottingham, Nottinghamshire, NG1 1GF United KingdomAurelia Bioscience offers lab-based services in bio-assay development and screening for small molecules and biologics using state of the art technologies applied to cell-based and biochemical assays. Technologies in our laboratory include: FLIPR Tetra, a fluorescence kinetic microplate reader and dispenser used for imaging intra-cellular calcium or potassium movement following ligand addition. FMAT, or Fluorescence MicroAssay Technology, a quasi con-focal plate reader, able to identify objects (beads and cells) in wells and measure the fluorescence in close proximity to the object whilst ignoring the surrounding fluorescence - used for cell and bead based binding studies. EnSpire label free, a technology developed by Corning Inc that uses specialised glass bottom microwell plates to image dynamic mass re-distribution of proteins in the membrane and proximal to the cytoplasm following ligand addition without the need for dyes or incorporation of cDNA. Guava FlowCyte, a flow cytometry system used to examine populations of cells in solution following treatment and labelling with fluorescence dyes. EnVision, a highly sensitive plate reader that can be used for both fluorescence and luminescence assays. Cellomics CX5 high content imager, able to examine both kinetic and fixed cell end point assays using imaging technology with fluorescently labelled antibodies or proteins at a number of magnifications. QuantiStudio 6 HT qPCR reader, able to detect mRNA changes in samples from cells in 384 well format. WES from Protein Simple, a system designed to perform high throughput Western Blot analysis to detect changes in specific proteins secreted from cells. All of the above can be applied to your biology of interest. Aurelia Bioscience are agnostic to disease area, we bring our technological know how to bear on to your biological questions and hopefully shed light on the mechanisms and identify compounds that interact with your target to, one day, be a future medicine. Previous diseases areas we have worked in include respiratory and inflammatory disease, oncology and cancer biology including hypoixia, muscule wasting disorders, cardiovascular disease and metabolic disorders. In addition we have our own 3-D biology R&D project, examining the biology of recombinant cells, primary cells and stem cells in an unique proprietary electrospun scaffold matrix for screening compounds and biologics.

56 Pennington, Orton Goldhay Orton Goldhay Peterborough, United Kingdom, PE2 5RB United KingdomASSAY with its global presence is a service provider of innovative and technologically advanced solutions for clinical trial management for the pharmaceutical, biotechnology and medical device industries. We also extend our services to clinical research organizations who require tailored services for managing their clinical trials. We focus on developing effective strategies for the collection, management and analysis of clinical data. With us, we guarantee that Sponsors, CROs and Sites can gain access to the best services for Phase I-IV clinical studies, study management and site management. We also ensure that the best skills and experiences are put in place to achieve the milestones efficiently. Together we can aim to achieve maximum patient safety and accurate data generation with highest quality and regulatory standards. Established in the UK in the year 2012, ASSAY Clinical Research started with a group of clinical research professionals who have been providing a variety of services for the pharmaceutical industry and other clinical research organizations. Gradually, ASSAY has gained recognition for its quality, timely services with affordable costs. Our services were quickly extended to European regions and India. With the deadly outbreak of Ebola and the need to test the vaccines, ASSAY was chosen for project management, data management and monitoring services and these services in Sierra Leone. With growing number of research activities around the globe, it is increasingly essential to keep up with the quality and timelines to save potential lives and curb the budget. With ever changing dimensions of research companies and the demand for therapeutic specific experience, the challenges to find the right resources has suddenly become massive leading to a demand and supply issue. ASSAY is here to help you with this. Our experienced team of project managers, clinical research associates and in-house team will be able to understand your challenges and needs in a time efficient manner and plan out the CAPA for you and implement it at any level which may be considered appropriate (Site Level, CRO level, Sponsor level, Country level, Region level or Global).

BioHub at Alderley Park, Mereside, Alderley Park, Cheshire, SK10 4TG United KingdomApex Molecular is a synthetic chemistry CRO providing specialist services and products to the pharmaceutical, biotechnology (life sciences), and applied chemical sectors. We provide fast, reliable, cost-effective delivery of chemistry synthesis & development services. In addition, we have 65+ years chemistry experience in our key staff to ensure we select and apply the correct technology solution for our customer’s needs. We pride ourselves on our excellent communication skills and flexible working model to match the needs of our customers. In our core chemistry lab we carry out customer-driven products on milligram to small kilogram scale to support research and development programmes. We also have a dedicated specialist facility for the handling and nonGMP synthesis of high potency compounds (e.g. cytotoxins targeted at the ADC, oncology market) on up to 10s grams scale as well as a precursor and controlled drugs license. We are experienced in the synthesis of a number of toxin classes (e.g. Auristatins, Maytansins, Duocarmycins, PDBs) and linker technologies (Maleimide, Hydroxysuccinimide, Val-Cit-PAB, Disulfide, PEGs etc) an offer a number of these as standard products. We have organic chemistry expertise that we employ of customer projects to design and synthesize compounds to support their development portfolios with a focus on drug discovery projects. Our chemistry services include custom synthesis, contract research and dedicated research FTEs both in high potency and non toxic, standard chemistry synthesis. We also offer process optimisation and scale-up services; with our 20L facility we can manufacture on small kilogram scale. Further areas of expertise include using precious metal catalysis and catalytic coupling chemistry, either generic or proprietary homogeneous and supported catalysts.chiral synthesis and biocatalysis.

Alderley Park Mereside Alderley Edge, Cheshire, SK10 4TG United KingdomApex Molecular is a synthetic chemistry CRO providing specialist services and products to the pharmaceutical, biotechnology (life sciences), and applied chemical sectors. We provide fast, reliable, cost-effective delivery of chemistry synthesis & development services. In addition, we have 65+ years chemistry experience in our key staff to ensure we select and apply the correct technology solution for our customer’s needs. We pride ourselves on our excellent communication skills and flexible working model to match the needs of our customers. In our core chemistry lab we carry out customer-driven products on milligram to small kilogram scale to support research and development programmes. We also have a dedicated specialist facility for the handling and nonGMP synthesis of high potency compounds (e.g. cytotoxins targeted at the ADC, oncology market) on up to 10s grams scale as well as a precursor and controlled drugs license. We are experienced in the synthesis of a number of toxin classes (e.g. Auristatins, Maytansins, Duocarmycins, PDBs) and linker technologies (Maleimide, Hydroxysuccinimide, Val-Cit-PAB, Disulfide, PEGs etc) an offer a number of these as standard products. We have organic chemistry expertise that we employ of customer projects to design and synthesize compounds to support their development portfolios with a focus on drug discovery projects. Our chemistry services include custom synthesis, contract research and dedicated research FTEs both in high potency and non toxic, standard chemistry synthesis. We also offer process optimisation and scale-up services; with our 20L facility we can manufacture on small kilogram scale. Further areas of expertise include using precious metal catalysis and catalytic coupling chemistry, either generic or proprietary homogeneous and supported catalysts.chiral synthesis and biocatalysis.

Alderley Park Mereside Alderley Edge, Cheshire, SK10 4TG United KingdomApex Molecular is a synthetic chemistry CRO providing specialist services and products to the pharmaceutical, biotechnology (life sciences), and applied chemical sectors. We provide fast, reliable, cost-effective delivery of chemistry synthesis & development services. In addition, we have 65+ years chemistry experience in our key staff to ensure we select and apply the correct technology solution for our customer’s needs. We pride ourselves on our excellent communication skills and flexible working model to match the needs of our customers. In our core chemistry lab we carry out customer-driven products on milligram to small kilogram scale to support research and development programmes. We also have a dedicated specialist facility for the handling and nonGMP synthesis of high potency compounds (e.g. cytotoxins targeted at the ADC, oncology market) on up to 10s grams scale as well as a precursor and controlled drugs license. We are experienced in the synthesis of a number of toxin classes (e.g. Auristatins, Maytansins, Duocarmycins, PDBs) and linker technologies (Maleimide, Hydroxysuccinimide, Val-Cit-PAB, Disulfide, PEGs etc) an offer a number of these as standard products. We have organic chemistry expertise that we employ of customer projects to design and synthesize compounds to support their development portfolios with a focus on drug discovery projects. Our chemistry services include custom synthesis, contract research and dedicated research FTEs both in high potency and non toxic, standard chemistry synthesis. We also offer process optimisation and scale-up services; with our 20L facility we can manufacture on small kilogram scale. Further areas of expertise include using precious metal catalysis and catalytic coupling chemistry, either generic or proprietary homogeneous and supported catalysts.chiral synthesis and biocatalysis.

DRG Abacus – Life Sciences Hub Wales 3 Assembly Square Cardiff Bay CF10 4PLFounded in 1995, Abacus International started life as a specialist health economics consultancy. Since then, we have evolved into a global provider of integrated market access services. In this time, the market access landscape for pharmaceutical and medical devices companies has changed immeasurably. Payers, and not prescribers, have become the primary decision makers; health technology assessment (HTA) bodies have emerged worldwide; and, most recently, we have seen the trend towards value-based pricing in place of free or reference pricing. As our environment has changed, however, Abacus International has always innovated and adapted to our surroundings – evolving our market access consultancy offering to meet the ever-changing needs of our clients. Today, our integrated market access services deliver effective health economic and evidence-based solutions across the product lifecycle: Payer Insight and Reimbursement Strategy – plan for success Systematic review – evaluate the evidence Health economics – develop cost-based value argument Clinical outcomes assessment – Develop and validate patient-centred outcome measures Health technology assessment – achieve positive recommendations Value communication – maximise access & uptake Strategic market access planning & consultancy

6 Talisman Business Centre, Talisman Road Bicester, Oxfordshire OX26 6HR United KingdomFounded in 1995, Abacus International started life as a specialist health economics consultancy. Since then, we have evolved into a global provider of integrated market access services. In this time, the market access landscape for pharmaceutical and medical devices companies has changed immeasurably. Payers, and not prescribers, have become the primary decision makers; health technology assessment (HTA) bodies have emerged worldwide; and, most recently, we have seen the trend towards value-based pricing in place of free or reference pricing. As our environment has changed, however, Abacus International has always innovated and adapted to our surroundings – evolving our market access consultancy offering to meet the ever-changing needs of our clients. Today, our integrated market access services deliver effective health economic and evidence-based solutions across the product lifecycle: Payer Insight and Reimbursement Strategy – plan for success Systematic review – evaluate the evidence Health economics – develop cost-based value argument Clinical outcomes assessment – Develop and validate patient-centred outcome measures Health technology assessment – achieve positive recommendations Value communication – maximise access & uptake Strategic market access planning & consultancy

DRG Abacus - Sigmatic ltd trading as Decision Resources Group 6 Talisman Business Centre Bicester , Oxfordshire, OX26 6HR United KingdomFounded in 1995, Abacus International started life as a specialist health economics consultancy. Since then, we have evolved into a global provider of integrated market access services. In this time, the market access landscape for pharmaceutical and medical devices companies has changed immeasurably. Payers, and not prescribers, have become the primary decision makers; health technology assessment (HTA) bodies have emerged worldwide; and, most recently, we have seen the trend towards value-based pricing in place of free or reference pricing. As our environment has changed, however, Abacus International has always innovated and adapted to our surroundings – evolving our market access consultancy offering to meet the ever-changing needs of our clients. Today, our integrated market access services deliver effective health economic and evidence-based solutions across the product lifecycle: Payer Insight and Reimbursement Strategy – plan for success Systematic review – evaluate the evidence Health economics – develop cost-based value argument Clinical outcomes assessment – Develop and validate patient-centred outcome measures Health technology assessment – achieve positive recommendations Value communication – maximise access & uptake Strategic market access planning & consultancy

274 Banbury Road England, OX2 7DY United KingdomAMICULUM is an independent, privately owned cluster of agencies which deliver value-added services and consultancy to pharmaceutical, biotechnology and medical device companies worldwide. AMICULUM comprises eight distinct agency businesses, each led by an experienced management team whose members are all actively involved in the delivery of services to clients. Each AMICULUM agency has its own in-house client service team and secure network, and all deliver services to a limited number of international pharmaceutical industry client companies.

Oriel House 26, The Quadrant London, TW9 1DL UKAMICULUM is an independent, privately owned cluster of agencies which deliver value-added services and consultancy to pharmaceutical, biotechnology and medical device companies worldwide. AMICULUM comprises eight distinct agency businesses, each led by an experienced management team whose members are all actively involved in the delivery of services to clients. Each AMICULUM agency has its own in-house client service team and secure network, and all deliver services to a limited number of international pharmaceutical industry client companies.

The Boathouse Clarence Mill Bollington, Cheshire, SK10 5JZ United KingdomAMICULUM is an independent, privately owned cluster of agencies which deliver value-added services and consultancy to pharmaceutical, biotechnology and medical device companies worldwide. AMICULUM comprises eight distinct agency businesses, each led by an experienced management team whose members are all actively involved in the delivery of services to clients. Each AMICULUM agency has its own in-house client service team and secure network, and all deliver services to a limited number of international pharmaceutical industry client companies.

1 Angel Court 14th Floor England, EC2R 7HJ United KingdomSince 1981, Analysis Group has provided expertise in economics, finance, health care analytics, and strategy to top law firms, Fortune 500 companies, global health care corporations, and government agencies. Our work is grounded in a collaborative approach that allows us to effectively integrate the best ideas from leading academic and industry experts with our more than 600 professionals. As a result, our clients receive thoughtful, pragmatic solutions to their most challenging business and litigation problems. Through our work in thousands of cases across multiple industries, we have become one of the largest economics consulting firms in North America, with 11 offices in the United States, Canada, and China.

Windmill House Innovation Way York, North Yorkshire, YO10 5BR United KingdomAptamer Group develops nucleic acid aptamers for use in research & development, biomarker discovery, diagnostics or therapeutic developments.

York Biocentre Innovation Way York, North Yorkshire, YO10 5NY United KingdomAptamer Group develops nucleic acid aptamers for use in research & development, biomarker discovery, diagnostics or therapeutic developments.

Second Floor Biocentre Heslington, England, YO10 5NY United KingdomAptamer Group develops nucleic acid aptamers for use in research & development, biomarker discovery, diagnostics or therapeutic developments.

Floor 2, BioCentre Innovation Way York, YO10 5NY United KingdomAptamer Group develops nucleic acid aptamers for use in research & development, biomarker discovery, diagnostics or therapeutic developments.

PO Box 42 Hexagon Tower Blackley Manchester M9 8ZS UKNitto Denko Avecia Inc manufactures gram to kilogram quantities of your oligonucleotide compliant with US and European cGMP guidelines.

Aldhams Farm Research Station, Dead Lane, Lawford, Manningtree, Essex, CO11 2NF, UKAgroChemex Ltd. was established as an agricultural and horticultural contract research organisation in 2000 and provides a truly independent class leading R & D facility. Our independence ensures confidentiality and a commitment to putting the customer first. Based at the former Aventis (Rhone-Poulenc) Global Centre of Excellence, AgroChemex is, according to many of our clients, in a unique position among agricultural contract research organisations owing to the world-class facilities available on-site. Few, if any, European independent contract research organisations can offer the range of capabilities available at AgroChemex, from our environmental fate facilities to computer controlled growth rooms, from the modern glasshouse and laboratory complex to the established orchards and arable research farm. Our GLP certificate was issued in spring 2000 and recently re-issued in August 2014 , as was our ORETO recognition. At AgroChemex Environmental we have the capability and expertise to conduct GLP ecotoxicology testing with a variety of aquatic and terrestrial species. AgroChemex Environmental boasts a newly installed, purpose built laboratory facility and offices at the Aldhams Farm Research Site in Lawford, Essex. The facility has been designated by the UK Home Office for the conduct of regulated procedures since 2012. The facility combines environmentally controlled laboratories, capable of meeting the OECD requirements for temperature, photoperiod and light levels; with analytical equipment to support the tests. If you’re looking for a bespoke and personal service with the highest quality and standards then AgroChemex Environmental’s skills and passion can help to guarantee the results your after.

Aldhams Farm/Dead La Manningtree, CO11 2NF United KingdomAgroChemex Ltd. was established as an agricultural and horticultural contract research organisation in 2000 and provides a truly independent class leading R & D facility. Our independence ensures confidentiality and a commitment to putting the customer first. Based at the former Aventis (Rhone-Poulenc) Global Centre of Excellence, AgroChemex is, according to many of our clients, in a unique position among agricultural contract research organisations owing to the world-class facilities available on-site. Few, if any, European independent contract research organisations can offer the range of capabilities available at AgroChemex, from our environmental fate facilities to computer controlled growth rooms, from the modern glasshouse and laboratory complex to the established orchards and arable research farm. Our GLP certificate was issued in spring 2000 and recently re-issued in August 2014 , as was our ORETO recognition. At AgroChemex Environmental we have the capability and expertise to conduct GLP ecotoxicology testing with a variety of aquatic and terrestrial species. AgroChemex Environmental boasts a newly installed, purpose built laboratory facility and offices at the Aldhams Farm Research Site in Lawford, Essex. The facility has been designated by the UK Home Office for the conduct of regulated procedures since 2012. The facility combines environmentally controlled laboratories, capable of meeting the OECD requirements for temperature, photoperiod and light levels; with analytical equipment to support the tests. If you’re looking for a bespoke and personal service with the highest quality and standards then AgroChemex Environmental’s skills and passion can help to guarantee the results your after.

Pentlands Science Park Penicuik Edinburgh UK EH26 0PZAngel Biotechnology offers recombinant proteins, cellular therapies, stem cells, antibodies, viruses, assay development, cell banking, stability studies, and manufacturing services.

4th Floor 44-46 Whitfield Street London, W1T 2RJ United KingdomArk Therapeutics is focused in the development of therapeutic drugs for vascular disease and cancer but also offers its biological manufacturing operations to provide process development and contract manufacturing services.

10 Steeple Industrial Estate Antrim, UK, BT41 1ABAscent Medical offers preclinical testing, animal studies, safety testing, clinical trials, and protocol development.

Babraham Research Park, Babraham Cambridge, CAMBS CB22 3AT United Kingdom, EuropeAlpha Biologics offers protein production, cell culture, process development, and manufacturing services.

BioEscalator, Innovation building University of Oxford, Roosevelt Drive Oxford, OX3 7FZ United KingdomAlchemab is a biotech company focused on discovering and developing novel therapeutics for patients with hard-to-treat diseases by harnessing the power of naturally protective antibodies.

55-56 Russell Square, Bloomsbury London, WC1B 4HP United KingdomAlchemab is a biotech company focused on discovering and developing novel therapeutics for patients with hard-to-treat diseases by harnessing the power of naturally protective antibodies.

1-4 Argyll Street 1-4 Argyll Street England, W1F 7TA United KingdomAtlant Clinical is a strong multinational contract research organization (CRO) offering a full range of clinical trials (Phases I-IV) and relevant support services throughout the US, Europe, Ukraine, Russia, and Middle Asia.

Holmes Chapel Road Lower Withington, SK11 9DP United KingdomAll aspects of antibody generation from immunogen design to reagent supply. Specialists in mouse monoclonal (hybridoma) generation. Also recombinant protein production, in-vitro antibody production, antibody modification, antibody characterisation/validation (including Biacore) and cell culture services. Specialists in antibody-based method development including Western blot, ELISA and rapid test. Flexible support for your antibody requirements from single task to multiple complex projects.

Blackcroft Barn, Holmes Chapel Road United Kingdom Lower Withington, Non-US/Canada, SK11 9DP United KingdomAll aspects of antibody generation from immunogen design to reagent supply. Specialists in mouse monoclonal (hybridoma) generation. Also recombinant protein production, in-vitro antibody production, antibody modification, antibody characterisation/validation (including Biacore) and cell culture services. Specialists in antibody-based method development including Western blot, ELISA and rapid test. Flexible support for your antibody requirements from single task to multiple complex projects.

Charnock Bradley Building Easter Bush, Roslin, Midlothian EH25 9RG, UK Midlothian, Midlothian, EH25 9RG United KingdomAxol Bioscience specialize in the supply of human cell culture systems and custom services for disease modeling and drug discovery. Our expertise includes induced pluripotent stem cell (iPSC) generation, CRISPR-Cas9 gene editing, iPSC differentiation and custom cell and tissue sourcing. We offer a variety of functionally validated human primary cells and human iPSC-derived cells from both healthy and patient donors alongside culture media and reagents that are tailored to support the optimal growth and maturation of our cells. This enables you to carry out your project in a physiologically relevant system that is not only reliable and easy to use but produces consistent results for robust replication studies. Our team is passionate about great science, delivering superb customer service and support and innovating future products to help customers advance their research faster. At Axol, innovation, quality and customer service are key.

Little Chesterford, England, CB10 1XL United KingdomAxol Bioscience specialize in the supply of human cell culture systems and custom services for disease modeling and drug discovery. Our expertise includes induced pluripotent stem cell (iPSC) generation, CRISPR-Cas9 gene editing, iPSC differentiation and custom cell and tissue sourcing. We offer a variety of functionally validated human primary cells and human iPSC-derived cells from both healthy and patient donors alongside culture media and reagents that are tailored to support the optimal growth and maturation of our cells. This enables you to carry out your project in a physiologically relevant system that is not only reliable and easy to use but produces consistent results for robust replication studies. Our team is passionate about great science, delivering superb customer service and support and innovating future products to help customers advance their research faster. At Axol, innovation, quality and customer service are key.

The Science Village, Chesterford Research Park United Kingdom Cambridge, Cambridgeshire, CB10 1XL United KingdomAxol Bioscience specialize in the supply of human cell culture systems and custom services for disease modeling and drug discovery. Our expertise includes induced pluripotent stem cell (iPSC) generation, CRISPR-Cas9 gene editing, iPSC differentiation and custom cell and tissue sourcing. We offer a variety of functionally validated human primary cells and human iPSC-derived cells from both healthy and patient donors alongside culture media and reagents that are tailored to support the optimal growth and maturation of our cells. This enables you to carry out your project in a physiologically relevant system that is not only reliable and easy to use but produces consistent results for robust replication studies. Our team is passionate about great science, delivering superb customer service and support and innovating future products to help customers advance their research faster. At Axol, innovation, quality and customer service are key.

59-60 Thames Street Windsor, SL4 1TX United KingdomAccovion provides regulatory consulting, medical services, clinical management, and pharmacovigilance.

13 Hwaley Street Camden Town London, NW18NP United KingdomThe Amaris Health Economics and Market Access (HEMA) brings together people of diverse backgrounds and combines robust quantitative and qualitative methods in order to provide a range of solutions to our pharmaceutical, biotech and medical device clients. Amaris HEMA is a global team of over 70 consultants spread out in 8 different offices around the world (Europe, North America and APAC). Our activities cover three main practices areas: - Health Economics Modelling (Cost-Effectiveness, Budget Impact, Sequential Modelling, Dynamic Modelling etc.) at both the global and the local levels (model adaptations) - RWE and Biostatistics (Secondary database analysis, Primary data collection, MAIC, ITC, NMAs etc.) - Evidence, Value and Access (SLRs, TLRs, GVDs, Landscape assessments, Evidence generation plans, KOL interviews etc.) The three Amaris HEMA practice areas collaborate on evidence review/package projects such as HTA submissions, with extensive experience in Canada, UK, France etc. Our profound understanding of the pharmaceutical market and solid scientific background makes us a valuable and reliable partner along all phases of development. We have strong expertise in both very specific and technical projects. Amaris’ added value lies in the quality of its teams and their attention to detail, as well as in the way the company capitalizes on their knowhow. Every employee is encouraged to develop a proactive, efficiency-oriented working style in order to provide only the most innovative solutions. The Health Economics and Market Access (HEMA) department of Amaris is part of the Amaris Group (http://amaris.com/en), an independent consulting company specialized in technology and management. Founded in 2007 in Switzerland, Amaris now employs more than 6,500 people based in more than 65 offices in 45 countries. Amaris provides services with a strong added value in all business sectors through five business lines: - Business & Management consulting - Information Systems and Technologies - Engineering and High technology - Telecommunications - Life Sciences (including Amaris HEMA).

Amaris - Work.Life 13 Hawley Crescent LONDON, NW1 8NP United KingdomThe Amaris Health Economics and Market Access (HEMA) brings together people of diverse backgrounds and combines robust quantitative and qualitative methods in order to provide a range of solutions to our pharmaceutical, biotech and medical device clients. Amaris HEMA is a global team of over 70 consultants spread out in 8 different offices around the world (Europe, North America and APAC). Our activities cover three main practices areas: - Health Economics Modelling (Cost-Effectiveness, Budget Impact, Sequential Modelling, Dynamic Modelling etc.) at both the global and the local levels (model adaptations) - RWE and Biostatistics (Secondary database analysis, Primary data collection, MAIC, ITC, NMAs etc.) - Evidence, Value and Access (SLRs, TLRs, GVDs, Landscape assessments, Evidence generation plans, KOL interviews etc.) The three Amaris HEMA practice areas collaborate on evidence review/package projects such as HTA submissions, with extensive experience in Canada, UK, France etc. Our profound understanding of the pharmaceutical market and solid scientific background makes us a valuable and reliable partner along all phases of development. We have strong expertise in both very specific and technical projects. Amaris’ added value lies in the quality of its teams and their attention to detail, as well as in the way the company capitalizes on their knowhow. Every employee is encouraged to develop a proactive, efficiency-oriented working style in order to provide only the most innovative solutions. The Health Economics and Market Access (HEMA) department of Amaris is part of the Amaris Group (http://amaris.com/en), an independent consulting company specialized in technology and management. Founded in 2007 in Switzerland, Amaris now employs more than 6,500 people based in more than 65 offices in 45 countries. Amaris provides services with a strong added value in all business sectors through five business lines: - Business & Management consulting - Information Systems and Technologies - Engineering and High technology - Telecommunications - Life Sciences (including Amaris HEMA).

Second Floor Citylabs 1.0 Nelson Street Manchester, Greater Manchester, M13 9NQ United KingdomAt APIS Assay Technologies we combine expertise in Molecular Diagnostic (MDx) Assay Development & Bioinformatics, machine learning and Software Development, with insights from academia and the priorities of global clinicians and health service providers. APIS is a disease and platform-agnostic company that provide bespoke solutions to our client's Assay Development and Bioinformatics & Software Development RFIs. The three main workstreams of our business are: 1. Contract Development of novel Molecular Diagnostic (MDx) Assay Development on medical diagnostic platforms. - Operating under an ISO 13485 QMS and supported by the necessary clinical & compliance teams we have expertise in developing NGS, PCR (RT-qPCR, qPCR, dPCR) and ELISA & ELONA IVD tests. Our onsite microbiology facilities mean we have the capabilities to develop infectious disease diagnostic tests in-house. - APIS offers complete end-to-end contract development solutions covering the entire development pipeline including prototype, pilot and commercial lot manufacturing. This also includes expertise in designing, managing, and documenting global infectious disease Clinical Performance studies under CE-IVDR, UKCA and FDA (510K) requirements. 2. Bioinformatics & Biodata Engineering, ML, AI and Software Development Solutions - Bespoke NGS Bioinformatic Pipeline development in Nextflow & CWL (RNAseq - sc & bulk; WGS; WES; proteomics) - Experts in Single Cell Omics: data processing, analysis & visualisation - Multi-OMICs data analysis platform development - Biomarker Discovery (Biostatistics, ML and AI) - In silico R&D and bespoke visualisation tools - Clinical Diagnostic consensus variant and copy number calling algorithms and reports - in silico retrospective clinical trial simulations utilising RWD/E for novel cohort stratification - Gene & Cell therapy vector integration (VISA) pipeline development (CAR T) 3. Biomarker Industrial Research and Development applied to diagnostic assays, targeting oncology, inflammatory, cardiovascular, infectious disease and inherited disease areas.

Unit 14 - Crowhill Farm, Ravensden Road, Wilden, Bedfordshire, MK 44 2QSThe Life Science Group is an independent UK based company formed of two divisions providing quality custom biological and in vitro products and services to Pharma, Biotech, CRO and Universities worldwide. The principals of the company have worked within the Life Science industry for over 30 years, specifically in the production of polyclonal and monoclonal antibodies and the collection, production and handling of cell culture sera and reagents. Life Science Production (LSP) offers a range of quality cell culture sera, both animal derived and human, including Foetal (Fetal) Bovine serum (FBS), Human AB serum, Human Platelet lysate, AQIX biopreservation medium, Bovine Serum Albumin (BSA) and associated reagents together with contract manufacture of cell culture sera, media, buffers and other fluids. www.lifescienceproduction.co.uk/ Antibody Production Services (APS) provides flexible and professional contract generation of antibodies, both monoclonal and polyclonal, together with a large range of associated services to meet every requirement including the optimisation and production of antibody existing hybridomas, adaptation of cells to serum free conditions, bulk antibody production and purification. www.antibodyproduction.co.uk/

Bedford, England United KingdomThe Life Science Group is an independent UK based company formed of two divisions providing quality custom biological and in vitro products and services to Pharma, Biotech, CRO and Universities worldwide. The principals of the company have worked within the Life Science industry for over 30 years, specifically in the production of polyclonal and monoclonal antibodies and the collection, production and handling of cell culture sera and reagents. Life Science Production (LSP) offers a range of quality cell culture sera, both animal derived and human, including Foetal (Fetal) Bovine serum (FBS), Human AB serum, Human Platelet lysate, AQIX biopreservation medium, Bovine Serum Albumin (BSA) and associated reagents together with contract manufacture of cell culture sera, media, buffers and other fluids. www.lifescienceproduction.co.uk/ Antibody Production Services (APS) provides flexible and professional contract generation of antibodies, both monoclonal and polyclonal, together with a large range of associated services to meet every requirement including the optimisation and production of antibody existing hybridomas, adaptation of cells to serum free conditions, bulk antibody production and purification. www.antibodyproduction.co.uk/

Unit 7, M11 Business Link Parsonage Lane Stansted Essex CM24 8GF EnglandAgar Scientific supplies consumables, accessories and equipment for microscopy.

Stansted Mountfitchet, England, CM24 United KingdomAgar Scientific supplies consumables, accessories and equipment for microscopy.

Tissue Typing Laboratory Box 209 Cambridge University Hospitals NHS Foundation Trust Hills Road, Cambridge, CB2 0QQThe Addenbrooke's Hospital Histocompatibility and Immunogenetics (Tissue Typing) laboratory provides a specialist histocompatibility and immunogenetics service for the East of England region and is part of the NIHR Cambridge Biomedical Research Centre. We offer a comprehensive range of molecular and serological techniques to identify Human Leukocyte Antigens (HLA), Killer Cell Immunoglobulin-Like Receptor (KIR) typing and immunological sensitisation to HLA. These tests are performed in support of the regional solid organ and stem cell transplant programmes, in the differential diagnosis of HLA associated diseases and in pharmacogenomics (adverse drug reactions). The laboratory is responsible for the selection of HLA compatible donor and recipient pairs for renal and stem cell transplantation and for HLA typing, HLA specific antibody screening and crossmatching in support of the small intestinal, multi-visceral, hepatic and cardio-thoracic transplant programmes.

Statham House Old Trafford, Manchester M32 0FP United KingdomAccepta is a leading supplier of high performance industrial and process water and waste water treatment chemicals; speciality chemicals, water testing kits and water quality analysis equipment; reagents, dosing pumps, meters and control equipment.

Unit 4 Fleet Business Park, Itlings Lane Hessle, HU13 9LX. United KingdomAGTC Bioproducts offers assay reagents, chemicals and solvents.

Itlings Lane Hessle, England, HU13 9LX United KingdomAGTC Bioproducts offers assay reagents, chemicals and solvents.

7a High Street, Moneymore Magherafelt, BT45 7PB Ireland

Saddleworth Business Centre, Huddersfield Rd, Delph, Oldham. OL3 5DF.Advanced Biomedical offers custom peptide synthesis, modification, labeling, and liposome manufacturing services.

5 Premus, Coldharbour Way, Aylesbury, Buckinghamshire, HP19 8APAston Chemicals is an independent distributor of Speciality Chemicals, providing the European Personal Care industry with innovative, high quality raw materials and outstanding levels of customer service. We offer our customers a completely integrated service, from dedicated R&D support to efficient delivery of products to manufacturing plants. We provide: Innovation and Technical Expertise Exceptional Customer Service Communication and Responsiveness Quality, Compliance and Traceability Cost-Effective Solutions and Total Value

Coldharbour Way Aylesbury, England, HP19 United KingdomAston Chemicals is an independent distributor of Speciality Chemicals, providing the European Personal Care industry with innovative, high quality raw materials and outstanding levels of customer service. We offer our customers a completely integrated service, from dedicated R&D support to efficient delivery of products to manufacturing plants. We provide: Innovation and Technical Expertise Exceptional Customer Service Communication and Responsiveness Quality, Compliance and Traceability Cost-Effective Solutions and Total Value

Avacta, Unit 20, Ash Way, Thorp Arch Estate United Kingdom Wetherby, West Yorkshire, LS23 7FA United KingdomAvacta has developed Affimer reagents and therapeutics - a class of non-antibody binding proteins that have been engineered to succeed in a wide range of applications where antibodies and aptamers have limitations. Affimer scaffolds are small (~100 amino acids, 12 kDa, 3 nm in diameter), stable (70°C

Pendeford House, Pendeford Business Park, Wobaston Rd, Pendeford, Wolverhampton, WV9 5APADAS exists to provide ideas, specialist knowledge and solutions to secure our food and enhance the environment. ADAS is the UK’s largest independent provider of agricultural and environmental consultancy, rural development services and policy advice. ADAS has a unique combination of insight and practical experience, underpinned by robust, informed, science-based information that allows us to meet the needs of both our domestic and international clients. Our great strength is our breadth and depth of expertise spanning the entire environmental sector.

7 Daimler Close, Royal Oak Industrial Estate, Daventry, Northants, United Kingdom, NN11 8QJWelcome to the AmegA Sciences Website Innovative World Leading Niche Formulators Some 25 years ago, plant pathologists from the Research & Development Department of AmegA Sciences identified the organism responsible for the turfgrass disease known as Dry Patch. Within four years the company's formulation chemists created the world's first treatment for the disease, verified the product though extensive independent trials testing and introduced it to market.

Henfield Road Small Dole, England, BN5 9XR United Kingdom

Walkers Road England, B98 9HD United KingdomAltaBioscience is recognised world-wide as a leading provider of custom peptide synthesis, custom antibody generation and processing, urinary steroid profiling, DNA synthesis, amino acid analysis and N-terminal protein sequencing. Based in the UK, with more than 40 years experience and ISO accreditation, our manufacturing and analysis laboratory serves clients in academia, pharmaceuticals and the food industry.

12 Howard Cornish Road Marcham United KingdomA new concept for the research antibody market: We have developed and introduced a global quality ranking standard for commercial research antibodies, called Aeonian Rating®. Using this ranking standard, we create a catalogue consisting of the best antibodies from a selection of contracted original manufacturers. In addition, we offer finding services to aid scientists and biomarker detection kit developers to identify the best candidate antibodies in the market using our Aeonian Rating®. Our service: Among the large amounts of available commercial antibodies to any one target protein we will identify the few candidate antibodies that most likely meet the customer's requirements. We will verify the data presented on the product sheet from the original manufacturer, avoiding rebranded products. Antibodies need to be accompanied with convincing data linked to the current batch/lot. The data need to demonstrate fitness for the application the antibody is required for. Those antibodies for which the epitope or immunizing peptide sequence is known enable us to check for potential cross-reactivity to related other proteins, especially when exhaustive validation data are absent. When such products are not available, we will make a clear statement regarding this for the best antibodies we do find. Our catalogue: The antibodies are eligible for our catalogue when the Aeonian Rating® is 70 or higher. The antibodies with the highest ranking are forever available with proven reproducible performance from batch to batch and in a consistent formulation (with a known purified IgG concentration). How are we different? Our unique approach comes to play when assessing the scientific integrity of the QC data presented by the manufacturer. Any claim of fitness for a certain application needs demonstrated by the presented data: The data need to be consistent with what is known from the literature and with the data from other available commercial antibodies. We will engage with the identified manufacturer to discuss their presented QC data of the current batch in comparison to previous batches and to check their stock situation before reporting back to the customer. We therefore serve customers who depend on a sustainable supply of product to last their projects, or to support their development of detection/quantification kits. As far as we can see, this service is nowhere else to be found. We are the first. Our Aeonian Rating® is a new quality ranking standard, providing a quantification of the level of fitness of the antibody for the application it is required for. Scientists and assay developers are saving a fortune by no longer having to buy and try tens of different antibodies for one target, while running the risk of buying the same antibody from different sources due to rebranding. Our unique approach will prevent all these trivial problems and allows the customer to take a precious short cut finding the right antibodies straight away.

Babraham Research Campus Babraham Cambridge CB22 3AT United KingdomAntitope offer services for evaluating immunogenicity, identifying T cell epitopes, producing humanized antibodies and generating non-immunogenic proteins.

Discovery Drive Cambridge, Cambridgeshire, CB2 0AX United KingdomAbcam is committed to supporting life scientists to achieve their mission, faster. We are a pioneering global organisation that identifies, develops, and distributes high-quality biological reagents, protein tools and custom cell engineering to drive crucial research, drug development and diagnostics. Working across the industry, our goal is to help advance the global understanding of biology and causes of disease, which enables new treatments and improved health. We collaborate with the life science community to co-create novel reagents, driven by our proprietary discovery platforms and extensive scientific insight.

Discovery Drive Cambridge Biomedical Campus Cambridge, CB2 0AX United KingdomAbcam is committed to supporting life scientists to achieve their mission, faster. We are a pioneering global organisation that identifies, develops, and distributes high-quality biological reagents, protein tools and custom cell engineering to drive crucial research, drug development and diagnostics. Working across the industry, our goal is to help advance the global understanding of biology and causes of disease, which enables new treatments and improved health. We collaborate with the life science community to co-create novel reagents, driven by our proprietary discovery platforms and extensive scientific insight.

Bullocks Lane Hope End Takeley, Essex, CM22 6TA United KingdomAzenta Life Sciences provides unrivaled sample exploration and management solutions to help our customers accelerate discovery, development, and delivery to bring impactful breakthroughs and therapies to market faster. We are the global leader in automated compound management for drug discovery, biological storage, and sample processing solutions. Azenta understands the importance of sample integrity and provides a comprehensive range of solutions across our leading capabilities of genomic services, sample repository services (SRS), consumables and instruments, data management and informatics, sample sourcing, and automated ultra-cold storage.

Times Square Newcastle upon Tyne, NE1 4EP United KingdomAeirtec provides custom high sensitivity multiplex immunoassay. Aeirtec's assay service is conducted according to the principles of GLP and ISO 17025:2005. Aeirtec has developed this unique high sensitivity technology to combat the loss of data encountered when measuring top of the hierarchy low abundance markers with generic assay sensitivities. Aeirtec operates a costing algorithm for unlimited permutations of sample and analyte numbers that provides rapid generation of a range of cost options, enables economies of scale and guaranteed delivery of data on time. Aeirtec offers advice or designs entirely marker panels relevant to the study and clinical question. Aeirtec also provides multivariate biostatistical analysis for integration of markers to strengthen study power.

The SmokeHouses Building Clifford Fort, North Shields Newcastle upon Tyne United KingdomAeirtec provides custom high sensitivity multiplex immunoassay. Aeirtec's assay service is conducted according to the principles of GLP and ISO 17025:2005. Aeirtec has developed this unique high sensitivity technology to combat the loss of data encountered when measuring top of the hierarchy low abundance markers with generic assay sensitivities. Aeirtec operates a costing algorithm for unlimited permutations of sample and analyte numbers that provides rapid generation of a range of cost options, enables economies of scale and guaranteed delivery of data on time. Aeirtec offers advice or designs entirely marker panels relevant to the study and clinical question. Aeirtec also provides multivariate biostatistical analysis for integration of markers to strengthen study power.

Luton, England United KingdomAnachem provides pipettes, laboratory equipment, and lab safety materials.

Cowley Road Cambridge CB4 0WSAcclarogen provides consultancy in all aspects of statistical genomics.

Cambridge, England United KingdomAcclarogen provides consultancy in all aspects of statistical genomics.

WYE VALLEY BUSINESS PARK HAY-ON-WYE, HR3 5PG UKAndersonBrecon offers packaging, storage, and distribution services in addition to expertise in clinical trials and analytical method development.

2 The Heights Brooklands Surrey KT13 0NY United KingdomAlloga provides a complete range of specialist pre-wholesale logistics services across Europe.

38 Lansdowne Road Bude Cornwall UKAvistron offers computational chemistry, synthetic organic chemistry, medicinal chemistry, and project management services.

St George s - University of London Cranmer Terrace London SW17 0REAnalytical Services International offers GLP/GCP facilities for bioanalytics in clinical studies, forensic toxicology, and therapeutic monitoring.

5 Lavender Close Caterham Surrey CR3 5DWAnalytical Services International offers GLP/GCP facilities for bioanalytics in clinical studies, forensic toxicology, and therapeutic monitoring.

England, CB22 3AT United KingdomBicycle Therapeutics was founded in mid-2009 as a spin out of the Medical Research Council Laboratory of Molecular Biology (Cambridge, UK), based on work of the scientific founders Professor Sir Gregory Winter and Professor Christian Heinis with initial seed funding from Atlas Ventures and Novartis Venture Fund.

Enterprise House 58B Main Street High Bentham Lancaster LA2 7HY UNITED KINGDOMAppliChem offers custom synthesis, cell culture media, reagent products and services.

Unit 9 Trinity Technology & Enterprise Campus, Pearse Street, Dublin 2 IRELANDArgutus Medical offers biomarkers, antibodies, and detection testing for the kidney, liver and pancreas.

Sandylands Farm Egloshayle Wadebridge, Cornwall PL27 6EL United KingdomAKL Research supplies stock intermediate chemicals.

Wadebridge, England, PL27 United KingdomAKL Research supplies stock intermediate chemicals.

University of Edinburgh, Roslin Midlothian, Scotland EH25 9PS United KingdomARK-Genomics is a high-throughput technology laboratory focused on studies of genome structure and genetic variation, gene expression and gene function.

7 Sycamore Close Cambridge, Cambridgeshire, CB1 8PG United Kingdom

Botanic House 100 Hills Road Cambridge, CB2 1PH United KingdomAt AIX Consultancy, we possess a unique balance of soft skills (creativity, communication, interpersonal, strategic thinking) and hard skills (analytical, financial, modelling, programming) to help our clients tackle the most challenging issues in pharmaceutical/medical technology development and value demonstration We believe that our novel approach can make health technology consulting and product development more efficient, thereby helping to reduce the overall cost of healthcare

Agriculture and Horticulture Development Board Stoneleigh Park Kenilworth Warwickshire CV8 2TLAHDB Cereals & Oilseeds: Independence, Innovation and Investment is a brief overview of who we are and what we do. Read about how AHDB Cereals & Oilseeds is funded, what we invest in and how we add to a sustainable cereals and oilseeds industry. Our Vision To create a dynamic UK arable supply chain where all are able to profit from a sustainable sector. Our Mission: To deliver a world-class arable industry through independence, innovation and investment.

Building 900 Babraham Research Campus Cambridge, Cambridgeshire, CB22 3AT United KingdomWe are Abzena. More than a CDMO, we are a responsible and dedicated Partner Research Organization (PRO) that takes care of your products from concept to patient. With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing. Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely. We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services. Your Vision. Our Mission. For Patients.

189 Castleroe Rd Coleraine, BT51 3RP United KingdomAxis Bioservices is a Northern Ireland-based Preclinical Contract Research Organisation with expertise in oncology, inflammation and respiratory diseases. Our services range from in vitro efficacy and mechanistic studies, to in vivo target engagement, with each study tailored to the unique requirements of the client. We listen, guide and advise clients through every step of the preclinical efficacy testing process, to deliver clear and robust results in a timely and cost-effective manner. This approach applies whether we are simply carrying out the in-life phase of a study or providing a complete package of analysis including flow cytometry analysis, bioanalysis and blood analysis, along with a detailed interpretation of results and recommendations. Please contact us with any questions about your study requirements.

Manchester M2 1HN , UNITED KINGDOMAmerican Elements' catalog of more than 15,000 products makes it the world’s largest metals and chemicals manufacturer devoted exclusively to advanced materials in industrial bulk and laboratory/research quantities. Our development programs have been a key source for academic and corporate research and new product development for over two decades. Fundamental expertise in the properties, applications, and cost-effective manufacturing of advanced and engineered materials, including ultra high purity refining (99.999%) and nanoscale materials, allows us to meet the needs of thousands of global manufacturers (including over 30% of the Fortune 50), all U.S. national laboratories and military branches, universities throughout the world, and customers in a wide range of industry fields, such as energy, electronics, aerospace, defense, automotive, optics, green technology, and pharmaceuticals. American Elements also produces customer proprietary formulations from our network of production facilities worldwide. Our dedication to the highest possible quality control and lot-to-lot consistency is equally matched by our goal to be at the forefront of creating a sustainable planet that continually moves towards improving the human experience for all mankind. Invention is the means of achieving this goal, and American Elements employees are driven to engineer and deliver the basic raw materials of innovation in a socially responsible manner. All we ask of our customers and partners is reflected in two simple words... Now Invent™

Hilton Business Park DE65 5UR United KingdomAyva Clinical Trials LTD UK specialise in delivering operational excellence in the global supply of comparator drugs for clinical trials and higher education research. Ayva Clinical Trials are a leading global company that specialises in providing validated comparator sourcing services with speed, accuracy and the highest ethical standard. With the knowledge and expertise to source the products you require when you need them. Because the parameters of each trial are different, Ayva Clinical Trials treat each client's project uniquely, offering advice and providing solutions to the client's needs. Our team is in-house, full time and highly experienced. We understand that research is impossible unless you can be assured that your supply of comparator medicine is secure, traceable and of the highest quality. Our quality assurance team ensures product quality control, including documentation such as Certificates of Analysis (CofAs), Certificates of Conformanace (CofCs), Batch Release Certificates (BRCs) and Statements of Authenticity (SofAs).

83 Baker St London, W1U 6AG United KingdomAirfinity is a disease forecasting company. It tracks, predicts and simulates population level disease outcomes in real time to inform decisions that can increase the global life span. Multiple industries rely on global structured time series data sets and advanced forecasting​, from weather, to transport, to financial markets. The life science industry is far behind and based on siloed, national and static disease data – often based on self-reporting. However, the life science industry is undergoing a data transformation driven by more and better personal health data, lower cost of diagnostics, better global data coverage and a range of other factors. Our approach is to ingest and structure any data point that has signal value and integrate it into our disease models in as close to real time as possible. Airfinity provides scenario planning tools and forecasts that can be understood, relied upon and used for decision making across the life science ecosystem. We use a unique quant analytics approach, combining advanced meta science, statistics, epidemiology and machine learning solutions to dynamically understand true disease prevalence and underlying outcome drivers. Airfinity has become the world's leading source of disease forecasting, specialising in infectious diseases, cardiovascular, metabolic, and renal diseases and other critical areas including RNA. For example, ask us about the potential impact of a vaccine or treatment on hospitalisations, the impact of a new variant or strain on candidate effectiveness, or what different uptake scenarios will mean for the burden of disease. Airfinity aims for the highest standards and quality, and at the same time operates at speed - clients get answers in hours, not months, so that we can be relied upon by the decision makers who know that the cost of failure is the cost of lives.

83 Baker St London, W1U 6AG United KingdomAirfinity is a disease forecasting company. It tracks, predicts and simulates population level disease outcomes in real time to inform decisions that can increase the global life span. Multiple industries rely on global structured time series data sets and advanced forecasting​, from weather, to transport, to financial markets. The life science industry is far behind and based on siloed, national and static disease data – often based on self-reporting. However, the life science industry is undergoing a data transformation driven by more and better personal health data, lower cost of diagnostics, better global data coverage and a range of other factors. Our approach is to ingest and structure any data point that has signal value and integrate it into our disease models in as close to real time as possible. Airfinity provides scenario planning tools and forecasts that can be understood, relied upon and used for decision making across the life science ecosystem. We use a unique quant analytics approach, combining advanced meta science, statistics, epidemiology and machine learning solutions to dynamically understand true disease prevalence and underlying outcome drivers. Airfinity has become the world's leading source of disease forecasting, specialising in infectious diseases, cardiovascular, metabolic, and renal diseases and other critical areas including RNA. For example, ask us about the potential impact of a vaccine or treatment on hospitalisations, the impact of a new variant or strain on candidate effectiveness, or what different uptake scenarios will mean for the burden of disease. Airfinity aims for the highest standards and quality, and at the same time operates at speed - clients get answers in hours, not months, so that we can be relied upon by the decision makers who know that the cost of failure is the cost of lives.

83 Baker St 83 Baker St, London W1U 6AG, W1U 6AG United KingdomAirfinity is a disease forecasting company. It tracks, predicts and simulates population level disease outcomes in real time to inform decisions that can increase the global life span. Multiple industries rely on global structured time series data sets and advanced forecasting​, from weather, to transport, to financial markets. The life science industry is far behind and based on siloed, national and static disease data – often based on self-reporting. However, the life science industry is undergoing a data transformation driven by more and better personal health data, lower cost of diagnostics, better global data coverage and a range of other factors. Our approach is to ingest and structure any data point that has signal value and integrate it into our disease models in as close to real time as possible. Airfinity provides scenario planning tools and forecasts that can be understood, relied upon and used for decision making across the life science ecosystem. We use a unique quant analytics approach, combining advanced meta science, statistics, epidemiology and machine learning solutions to dynamically understand true disease prevalence and underlying outcome drivers. Airfinity has become the world's leading source of disease forecasting, specialising in infectious diseases, cardiovascular, metabolic, and renal diseases and other critical areas including RNA. For example, ask us about the potential impact of a vaccine or treatment on hospitalisations, the impact of a new variant or strain on candidate effectiveness, or what different uptake scenarios will mean for the burden of disease. Airfinity aims for the highest standards and quality, and at the same time operates at speed - clients get answers in hours, not months, so that we can be relied upon by the decision makers who know that the cost of failure is the cost of lives.

184 Park Drive Milton Park Abingdon , OX14 4SE United KingdomFounded in 1987, AMBSIO is recognised as a leading global source of unique products & custom services for life science research.

The Biosphere Draymans Way, Newcastle Helix Newcastle upon Tyne, Tyne & Wear , NE4 5BX United KingdomA proven, experienced CRO and service-provider, Alcyomics has developed several unique non-animal, non-artificial human based in vitro assays that transform drug development by enabling early and accurate identification of safe and efficacious compounds. We have extensive experience in cellular assays, 3D tissue models, 3D disease models and many more. Our sensitive and highly customisable assays significantly improve the testing process making it faster, more effective and better at predicting clinical outcomes. We help clients reduce the cost of drug development, reduce the use of animal models, improve speed to market while providing a better return on investment.

Henry Street Regents Centre, Gosforth NE3 3LS United KingdomA proven, experienced CRO and service-provider, Alcyomics has developed several unique non-animal, non-artificial human based in vitro assays that transform drug development by enabling early and accurate identification of safe and efficacious compounds. We have extensive experience in cellular assays, 3D tissue models, 3D disease models and many more. Our sensitive and highly customisable assays significantly improve the testing process making it faster, more effective and better at predicting clinical outcomes. We help clients reduce the cost of drug development, reduce the use of animal models, improve speed to market while providing a better return on investment.

Haematological Sciences Institute of Cellular Medicine Newcastle University Framlington Place Newcastle Upon Tyne NE2 4HH, UKA proven, experienced CRO and service-provider, Alcyomics has developed several unique non-animal, non-artificial human based in vitro assays that transform drug development by enabling early and accurate identification of safe and efficacious compounds. We have extensive experience in cellular assays, 3D tissue models, 3D disease models and many more. Our sensitive and highly customisable assays significantly improve the testing process making it faster, more effective and better at predicting clinical outcomes. We help clients reduce the cost of drug development, reduce the use of animal models, improve speed to market while providing a better return on investment.

C/O Haematological Sciences Institute of Cellular Medicine, Newcastle University Newcastle-Upon-Tyne, Tyne and Wear, NE2 4HH United KingdomA proven, experienced CRO and service-provider, Alcyomics has developed several unique non-animal, non-artificial human based in vitro assays that transform drug development by enabling early and accurate identification of safe and efficacious compounds. We have extensive experience in cellular assays, 3D tissue models, 3D disease models and many more. Our sensitive and highly customisable assays significantly improve the testing process making it faster, more effective and better at predicting clinical outcomes. We help clients reduce the cost of drug development, reduce the use of animal models, improve speed to market while providing a better return on investment.

D10 Ground 101 Nottingham, NG90 2PR United KingdomBoots Analytical Services offers method development/validation, stability testing, release testing, and microbiological testing services.

Nottingham, England United KingdomBoots Analytical Services offers method development/validation, stability testing, release testing, and microbiological testing services.

England United KingdomBroughton Laboratories provides QC batch release testing, stability testing, and laboratory software.

Broughton Laboratories Coleby House The Water Mill Park Broughton Hall Skipton North Yorkshire BD23 3AGBroughton Laboratories provides QC batch release testing, stability testing, and laboratory software.

The Babraham Research Campus, Babraham, Cambridge CB22 3AT, UKBabraham Cambridge CB22 3AT UKBabraham Biomarker Service provides molecular biology services for sample analysis and processing.

Basepoint Business Centre, Tewkesbury Business Park, Oakfield Close, Tewkesbury GL20 8SD, United KingdomBIOAXXESS® Consulting represents an independent network to promote, advise on, procure or outsource best- or first-in-class technology solutions to provide our clients within life sciences, in vitro diagnostics (IVD) and R&D of biopharma and biotech with customized and fit-for-purpose reagents and technology solutions.

Basepoint Business Centre Oakfield Close, Tewkesbury Business Park Tewkesbury, GL20 8SD United KingdomBIOAXXESS® Consulting represents an independent network to promote, advise on, procure or outsource best- or first-in-class technology solutions to provide our clients within life sciences, in vitro diagnostics (IVD) and R&D of biopharma and biotech with customized and fit-for-purpose reagents and technology solutions.

21-25 St James St Okehampton, Devon EX20 1DH United KingdomButt Park supplies various fine chemicals.

Okehampton, England, EX20 United KingdomButt Park supplies various fine chemicals.

Regus House, Falcon Drive Cardiff Bay CF10 4RUBlue Frog Scientific Limited was founded in 2010 following a management buy-out of an established regulatory affairs consultancy business. Blue Frog's philosophy is achieving regulatory compliance through the application of good science, innovation and clarity; ensuring that all submissions are prepared efficiently and to a high standard. We offer scientific and regulatory affairs services with particular experience in chemicals, human pharmaceuticals, veterinary medicines, agrochemicals and feed additives. Based in Edinburgh and Cardiff, our core team of consultants coordinates operations and our comprehensive network of associates ensures that we can assist our clients in all areas of regulatory compliance. We have particular in-house strengths in regulatory affairs, chemistry, toxicology, ecotoxicology and environmental fate. We utilise our associates when we need leaders in specific fields (e.g. reproductive toxicology) to address issues requiring an expert opinion, statement or report.

BioPark, Broadwater Road Welwyn Garden City, Hertfordshire AL7 3AX United KingdomBABS Biomarker Services offers biomarker services.

Cantium House, Citylink Centre Railway Approach Wallington Surrey SM6 0DZ UKBibra provides consultancy services in a number of important toxicology areas.

103 Clarendon Road Leeds, LS2 9DF United KingdomBadrilla supplies monoclonal and polyclonal antibodies.

Leeds, England United KingdomBadrilla supplies monoclonal and polyclonal antibodies.

Bergen Way King's Lynn Norfolk PE30 2JJ UKBespak is a leading global supplier of drug delivery devices for inhaled and injectable products.

1 Thane Road West D10 building Nottingham EnglandBCM (Boots Contract Manufacturing) offers the formulation, manufacture and quality testing of health and beauty products.

Babraham Research Campus Cambridge, CB22 3AT United KingdomBabraham Bioscience Technologies (BBT) of the Babraham Institute offers its scientific facilities to support bioinformatics, epigenomics, FACS analysis, gene targeting, mass spectrometry, and antibody production.

111 Appleton Road England, HU5 4PF United KingdomDesign, packaging development, prototyping, industrialization. Dosing and Medical Devices. Packaging For Pharma and FMCG. E commerce, SMART packaging, Animations, 3 D prints of concept, Prototyping, Pilot tooling for plastic packaging. Paper packaging development, prototyping and print. Packaging validation and implementation on industrial scale.

5 Orwell Furlong Cowley Road Cambridge, Cambridgeshire, CB4 0WY United KingdomBiorbyt supplies antibodies, proteins, small molecules, kits, and molecular biology products.

Woodlands St George's Road Rochdale Lancashire, OL11 5YN United KingdomBellen Chemistry, established in 2007, originally focused on the design and development of hundreds of novel heterocycles. Over a number of years, our innovative capabilities and reliable performance were gradually becoming more recognized in the marketplace, and our customers encouraged us to develop CRO/CDMO business with them. In order to provide better solutions for our customers, the company has undertaken three rounds of venture capital financing to support our dynamic growth. A manufacturing plant has been constructed in Shandong in addition to a new process R&D center in Shanghai since 2017, and the capital investment is also enabling the relocation of our R&D innovation center to a new site in Beijing by end of 2020. In the past 14 years, the company has grown from 6 employees to over 800 employees. In line with our global service commitment, we have also set up Bellen branches in the US, UK, Canada, France and Japan so as to provide better and faster services to our local customers. Today we provide project support to a variety of different customers, from innovative biotech to global giant pharmaceutical companies. Bellen is committed to continuing investing in innovation and state-of-the-art facilities to enable a one-stop-shop chemistry service platform, adding value to your project from library synthesis to API GMP manufactory. Our Key Services & Capabilities: - Key intermediates & RSMs (non-GMP & GMP) - cGMP APIs - Flow chemistry & Biocatalysis - Process development & optimisation - Process safety assessment - Early phase scale up - Late phase API & intermediates manufacturing - Solid Phase & Recrystallisation platforms (New for 2023)

BioFocus Chesterford Research Park Saffron Walden Essex CB11 4BEBioFocus offers a comprehensive suite of discovery products and services. These are available separately or as an integrated drug discovery solution, backed by a centralized project management system.

England United KingdomBioFocus offers a comprehensive suite of discovery products and services. These are available separately or as an integrated drug discovery solution, backed by a centralized project management system.

15 Albert Drive Site J Unit 2 Burgess Hill, West Sussex, RH15 9TN United KingdomBioIVT, formerly BioreclamationIVT, is a leading global provider of high-quality biological specimens and value-added services. We specialize in control and disease state samples including human and animal tissues, cell products, blood and other biofluids. Our unmatched portfolio of clinical specimens directly supports precision medicine research and the effort to improve patient outcomes by coupling comprehensive clinical data with donor samples. And as the world’s premier supplier of ADME-toxicology model systems, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and the effects on disease processes. By combining our technical expertise, exceptional customer service, and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE. For more information about our processes on the regulatory oversight of Human Biological Specimens (HBS), please visit our website, www.bioivt.com, for more information. Specific information related to our quality and ethical assurances can be found here: https://www.bioivt.com/about/quality-assurance/.

2A Orchard Road Royston, England, SG8 5HD United KingdomBioIVT, formerly BioreclamationIVT, is a leading global provider of high-quality biological specimens and value-added services. We specialize in control and disease state samples including human and animal tissues, cell products, blood and other biofluids. Our unmatched portfolio of clinical specimens directly supports precision medicine research and the effort to improve patient outcomes by coupling comprehensive clinical data with donor samples. And as the world’s premier supplier of ADME-toxicology model systems, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and the effects on disease processes. By combining our technical expertise, exceptional customer service, and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE. For more information about our processes on the regulatory oversight of Human Biological Specimens (HBS), please visit our website, www.bioivt.com, for more information. Specific information related to our quality and ethical assurances can be found here: https://www.bioivt.com/about/quality-assurance/.

50 North Lindsay Street Scotland, DD1 1QE United KingdomBioDundee is a public/private partnership between the life sciences organisations within and around Dundee. BioDundee was established in 1997 to promote the Dundee sector as a centre of world class life science activity and to build the strength of the local life sciences sector through partnership working, networking, knowledge and skills development. BioDundee regularly organises training and networking events for anyone working in this sector. Our events are tailored towards the local life science community but are open to professionals or students visiting the area.

5 Rockware Avenue Greenford Middlesex - UB6 OAA London UKBritish Enterprises offers manufacturing of hard gelatine and vegetarian capsules, soft capsules,vitamins,tablets, and paracetamol and ibuprofen powders.

London, England United KingdomBritish Enterprises offers manufacturing of hard gelatine and vegetarian capsules, soft capsules,vitamins,tablets, and paracetamol and ibuprofen powders.

Plymouth International Medical and Technology Park, 24 Brest Road Derriford, Plymouth PL6 5XP United KingdomBioVault offers human tissue processing, banking, and acquisition services.

The BioHub at Alderley Park, Mereside, Alderley Park, Alderley Edge. Cheshire. SK10 4TG. UK

Hull, England United KingdomB&K Universal provides animal breeding for medical research.

Alchemy House Tom Mc Donald Avenue Medipark, Dundee, DD2 1NH, UKBBInternational offers assay development, custom conjugation, colloids, and contract manufacturing services.

Archway House 77 Ty Glas Avenue Cardiff, CF14 5DX United KingdomBBInternational offers assay development, custom conjugation, colloids, and contract manufacturing services.

204 George Street Glasgow, Scotland, G1 1XW United Kingdom

330 Cambridge Science Park Milton Road Cambridge, Cambridge, CB4 0WN United KingdomResearch, development and provision of medical diagnostic testing

Temple Chambers 3-7 Temple Avenue London, EC4Y 0HP United KingdomBiotrial offers in vivo studies and GLP safety pharmacology services.

The Advanced Manufacturing Park Unit 5a, Selden Way Rotherham, South Yorkshire, s60 5xa United KingdomBioServUK Ltd is a CMO with expertise in upstream production and downstream processing of antibodies and recombinant proteins from mammalian, bacterial and insect cell cultures. For over 25 years, BioServUK has developed an established client base for provision of quality antibody reagents to the life science research and IVD markets. All contract production is performed to ISO 9001 quality standard, comprising fully auditable SOPs and downstream production sheets for all aspects of the process. The team of nine staff have extensive experience across all facets of antibody (monoclonal, polyclonal, bulk growth) and recombinant protein production. We have state of the art facilities at The Advanced Manufacturing Park, Sheffield. Part of the Calibre Scientific group of Companies, BioServUK have access to the products and support from over 16 Companies in the global life-science manufacturing and distribution space.

217 Portobello England, S1 4DP United KingdomBioServUK Ltd is a CMO with expertise in upstream production and downstream processing of antibodies and recombinant proteins from mammalian, bacterial and insect cell cultures. For over 25 years, BioServUK has developed an established client base for provision of quality antibody reagents to the life science research and IVD markets. All contract production is performed to ISO 9001 quality standard, comprising fully auditable SOPs and downstream production sheets for all aspects of the process. The team of nine staff have extensive experience across all facets of antibody (monoclonal, polyclonal, bulk growth) and recombinant protein production. We have state of the art facilities at The Advanced Manufacturing Park, Sheffield. Part of the Calibre Scientific group of Companies, BioServUK have access to the products and support from over 16 Companies in the global life-science manufacturing and distribution space.

The Innovation Centre 217 Portobello Sheffield, S1 4DP United KingdomBioServUK Ltd is a CMO with expertise in upstream production and downstream processing of antibodies and recombinant proteins from mammalian, bacterial and insect cell cultures. For over 25 years, BioServUK has developed an established client base for provision of quality antibody reagents to the life science research and IVD markets. All contract production is performed to ISO 9001 quality standard, comprising fully auditable SOPs and downstream production sheets for all aspects of the process. The team of nine staff have extensive experience across all facets of antibody (monoclonal, polyclonal, bulk growth) and recombinant protein production. We have state of the art facilities at The Advanced Manufacturing Park, Sheffield. Part of the Calibre Scientific group of Companies, BioServUK have access to the products and support from over 16 Companies in the global life-science manufacturing and distribution space.

Dover Lane Manchester, M1 6NG United KingdomBio-Shape is a start-up company developed by academics from Manchester and Liverpool Universities to support the biotechnology industry. Our purpose is to provide bespoke analytical services using mass spectrometry-based methods to analyse large and complex biomolecules with a focus on biopharmaceuticals. We are developing our capabilities beyond this and into waste management, analysing high-value biomolecules from waste streams to help companies transition towards a circular economy.

4-9 Old Station Business Park Compton, Berkshire, RG20 6NE United KingdomBiosynth is an innovative global life sciences reagents, custom synthesis and manufacturing services company that secures the fragment pharma and diagnostic supply chain. With an unrivalled research product portfolio and end-to-end manufacturing services, Biosynth are science led and customer focused to solve problems and deliver key reagents at scale and with quality. Our expertise and capability runs across fine chemicals/small molecules, peptides and key biologics all from one trusted partner. We manufacture and source a vast range of chemical and biochemical products, and take pride in delivering products that others cannot. We provide a full range of products and services to support life science research and development, with more than a million products in our research catalog and many hundreds of complex manufacturing service projects. Our small molecule chemistry specialties include enzyme substrates, carbohydrate and nucleoside chemistry, as well as intermediates, APIs and controlled substances. Customers can partner across the full product life cycle with no need to change suppliers, with manufacturing services from the first idea to the finished product, from route scouting and optimization to GMP or ton scale production at sites across Europe and Asia. Biosynth’s peptide division, based in the US and Europe, has over 40 years of expertise in assisting pharma and diagnostics customers and specializes in custom peptide synthesis from nmol up to multiKg scale. From peptide discovery and lead optimization, including our own CLIPS™ technology to lock peptides into active conformations, to GMP NCEs and neoantigens to cover all your needs. Biosynth has a synergistic offering of critical biological raw materials, including mono- and polyclonal antibody production and our unique epitope mapping service as a platform to support your antibody development, including patent applications. Biosynth’s enzyme products and solutions are at the forefront of biocatalysis, and also include custom enzyme development and production. Through the Biosynth group we also offer development of antibodies, antigens and supply of plasma for in vitro diagnostics. *Biosynth and the Biosynth Group includes the previous and associated brands: Carbosynth, vivitide, New England Peptide, Peptides International, Pepscan, Eucodis Bioscience and Aalto Bio Reagents. For more information please visit our website: https://www.biosynth.com/

8 & 9 Old Station Business Park Compton , Berkshire, RG20 6NE United KingdomBiosynth is an innovative global life sciences reagents, custom synthesis and manufacturing services company that secures the fragment pharma and diagnostic supply chain. With an unrivalled research product portfolio and end-to-end manufacturing services, Biosynth are science led and customer focused to solve problems and deliver key reagents at scale and with quality. Our expertise and capability runs across fine chemicals/small molecules, peptides and key biologics all from one trusted partner. We manufacture and source a vast range of chemical and biochemical products, and take pride in delivering products that others cannot. We provide a full range of products and services to support life science research and development, with more than a million products in our research catalog and many hundreds of complex manufacturing service projects. Our small molecule chemistry specialties include enzyme substrates, carbohydrate and nucleoside chemistry, as well as intermediates, APIs and controlled substances. Customers can partner across the full product life cycle with no need to change suppliers, with manufacturing services from the first idea to the finished product, from route scouting and optimization to GMP or ton scale production at sites across Europe and Asia. Biosynth’s peptide division, based in the US and Europe, has over 40 years of expertise in assisting pharma and diagnostics customers and specializes in custom peptide synthesis from nmol up to multiKg scale. From peptide discovery and lead optimization, including our own CLIPS™ technology to lock peptides into active conformations, to GMP NCEs and neoantigens to cover all your needs. Biosynth has a synergistic offering of critical biological raw materials, including mono- and polyclonal antibody production and our unique epitope mapping service as a platform to support your antibody development, including patent applications. Biosynth’s enzyme products and solutions are at the forefront of biocatalysis, and also include custom enzyme development and production. Through the Biosynth group we also offer development of antibodies, antigens and supply of plasma for in vitro diagnostics. *Biosynth and the Biosynth Group includes the previous and associated brands: Carbosynth, vivitide, New England Peptide, Peptides International, Pepscan, Eucodis Bioscience and Aalto Bio Reagents. For more information please visit our website: https://www.biosynth.com/

Steel City House West Street Sheffield, South Yorkshire, S1 2GQ United KingdomBresMed was established in 2005, and we now have more than 100 staff based in the UK, Ireland, the Netherlands, USA and India. We are an independent health economic and outcomes research consultancy. BresMed provides health economic solutions to the global pharmaceutical industry.

Manchester Science Park Rutherford House Pencroft Way Manchester , M15 6SZ United KingdomBioxydyn is a specialist provider of groundbreaking MRI applications and imaging services. We develop powerful MRI-based diagnostic imaging applications and services to improve clinical diagnostics and patient treatment. Our products and services are applied in a range of diseases areas, including respiratory diseases, neurological conditions, cancer and inflammation.

The Stone House, 9 Weymouth Street London, W1W 6DB United KingdomBiolab Medical Unit is a nutritional biochemistry laboratory that can measure vitamin and mineral levels, toxic metals, and other biochemical levels.

The Raylor Centre James Street York, YO10 3DW United KingdomBioquote Limited supplies bioproducts for the bioscience industry.

Spectrum House, Llys Edmund Prys St. Asaph Business Park, St. Asaph Denbighshire, LL17 0JABio-Check (UK) was founded by Phil. Goodwin in 2004 and operates from a modern, dedicated facility in the city of St. Asaph, North Wales. The majority of our customers are laboratories providing testing and analysis services to the food and drink industry - a sector under the spotlight as never before. As such, the role labs play in ensuring the safety and validity of consumer products is more vital than ever. Bio-Check (UK) is dedicated to meeting those ever-growing needs and demands of our customers. We guarantee the quality of the products and services we provide, more mindful than ever of the increasing pressure on our food producers and the laboratory services on which they depend. Bio-Check's Quality Management System is IS0 9001:2008 approved for development and manufacture of test kits for the detection of contaminants and adulterants in food products. Bio-Check (UK) founder Phil Goodwin and his team have many decades of experience in the field of in vitro diagnostic testing for medical diagnostics and research, pharmaceutical analysis and food testing applications. They have been responsible for the commercialisation of many immunoassays and other diagnostic techniques, including food allergy diagnostics, detection of allergens, wheat gluten, mycotoxins and meat species adulteration detection in food. Bio-Check (UK) sees the extra demands on the food and drink industry as a challenge and an opportunity; a challenge to find the best methods needed to maintain a reliable and transparent food chain, and an opportunity to reaffirm the UK’s food and drink industry as the world’s best. If you share this aim and are interested in our laboratory and on-site test kits, analytical services, training and pre-audit consultancy services we would like to speak to you.

Spectrum House, Llys Edmund Prys St. Asaph Business Park, St. Asaph Denbighshire, LL17 0JA United KingdomBio-Check (UK) was founded by Phil. Goodwin in 2004 and operates from a modern, dedicated facility in the city of St. Asaph, North Wales. The majority of our customers are laboratories providing testing and analysis services to the food and drink industry - a sector under the spotlight as never before. As such, the role labs play in ensuring the safety and validity of consumer products is more vital than ever. Bio-Check (UK) is dedicated to meeting those ever-growing needs and demands of our customers. We guarantee the quality of the products and services we provide, more mindful than ever of the increasing pressure on our food producers and the laboratory services on which they depend. Bio-Check's Quality Management System is IS0 9001:2008 approved for development and manufacture of test kits for the detection of contaminants and adulterants in food products. Bio-Check (UK) founder Phil Goodwin and his team have many decades of experience in the field of in vitro diagnostic testing for medical diagnostics and research, pharmaceutical analysis and food testing applications. They have been responsible for the commercialisation of many immunoassays and other diagnostic techniques, including food allergy diagnostics, detection of allergens, wheat gluten, mycotoxins and meat species adulteration detection in food. Bio-Check (UK) sees the extra demands on the food and drink industry as a challenge and an opportunity; a challenge to find the best methods needed to maintain a reliable and transparent food chain, and an opportunity to reaffirm the UK’s food and drink industry as the world’s best. If you share this aim and are interested in our laboratory and on-site test kits, analytical services, training and pre-audit consultancy services we would like to speak to you.

Faraday Bldg, Nottingham NG7 2QP UKAt BioDock we are proud to be an industry leader in the storage of biological samples. Our technologically-advanced facility is based in Nottingham, in the heart of the UK. Storing over 500,000 samples from over 70 different countries, we are well practised in the requirements and processes needed to store a wide array of biological samples from across the world. Our facility provides storage for samples at a range of different temperatures; -20 degrees, -80 degrees and -196 degrees liquid nitrogen. Our samples include purified stem cells, human tissue, whole blood, clinical specimens and biological solutions. We are also one of the only cryogenic storage facilities to boast a fully-operational clean room, a facility which enables the production of live cell cultures.

Biocon (London) Limited 50, Elm Quay Court 30, Nine Elms Lane SW8 5DF, London, UKBiocon Pharmaceuticals offers synthetic chemistry, molecular biology, and APIs.

John Vane Science Centre Charterhouse Square London EC1M 6BQWe are a constantly evolving genomics core facility. With our experienced team of scientists our goal is to partner all stages of your genetic or genomic research projects, including project proposal, experimental design, training, technical support, analysis and interpretation of data Our Timeline. Founded in 2000 the Genome Centre at Barts and The London School of Medicine and Dentistry has successfully provided genetic and genomic research facilities to researchers within Queen Mary University and the wider Life Sciences research community for over 10 years Initial investment in 2000 provided robotics, capillary sequencing and real-time PCR capability which we still support. Further investment in 2006 in microarray from Illumina (updated in 2011 to the iScan) enabled us to support high density SNP, Gene Expression and Methylation analysis. 2008 and 2009 saw adoption of Illumina's next generation sequencing technology and the associated IT infrastructure. 2012 has seen us rolling out library preps using the Fluidigm and targeted sequencing on the MiSeq. With this portfolio of platforms the centre can facilitate studies of the genome, transcriptome and epigenome on any scale.

33D Julians Road Stevenage, Hertfordshire, SG1 3ES United KingdomBio-Mimetic Chromatography Ltd offers HPLC based bio-mimetic property measurements for drug discovery compounds. it includes protein and phospholipid binding as well as lipophilicity of the compounds at three different pH. Based on the data we estimate and rank in-vivo properties of the compounds based on published and validated models. These models include volume of distribution, drug efficiency, brain tissue binding, lung tissue binding, skin absorption, blood/brain distribution, phospholipidotic potential, cellular accumulation. We offer consultancy to setup these measurements and we are offering developing new local models based on the client's compounds data.

Business & Technology Centre, Bessemer Drive Stevenage, Herts, SG1 2DX United KingdomBio-Mimetic Chromatography Ltd offers HPLC based bio-mimetic property measurements for drug discovery compounds. it includes protein and phospholipid binding as well as lipophilicity of the compounds at three different pH. Based on the data we estimate and rank in-vivo properties of the compounds based on published and validated models. These models include volume of distribution, drug efficiency, brain tissue binding, lung tissue binding, skin absorption, blood/brain distribution, phospholipidotic potential, cellular accumulation. We offer consultancy to setup these measurements and we are offering developing new local models based on the client's compounds data.

5 Mount Crescent Broadmeadows South Normanton Alfreton Derbyshire DE55 3NS Registered in England & Wales 4289839Brian Johnson Associates provides high quality technical support, to cover temporary resource shortages or to add to in-house expertise.

Alfreton, England, DE55 United KingdomBrian Johnson Associates provides high quality technical support, to cover temporary resource shortages or to add to in-house expertise.

11-29 Fashion Street London, 1E 6PX United KingdomBlack Swan Analysis is a boutique business analysis consultancy based in the UK. Founded in 2007, the company provides a range of services to biotechs and university spin-outs, business development departments, CROs and investment companies. Our areas of expertise include forecasting excellence and patient segmentation which are supported by an array of proprietary tools such as comprehensive epidemiology and pricing databases. Typical services include: • Dynamic oncology flow modelling to value oncology assets at any stage of development (Onco-Strat) • Regulator/ due- diligence- ready epidemiology data (Epiomic segmentation database) • Prescription-only medicine ex-manufacturer pricing data for Europe (Rx Price Index) • Custom disease area reports • Competitive intelligence & market landscape assessments • Product valuations / forecast models and market assessments Our philosophy at Black Swan Analysis is to create a collaborative environment that enables us to provide an unparalleled level of satisfaction and quality to our clients. Black Swan Analysis is part of Evaluate Ltd

Birmingham, UKBodycote Health Sciences offers analytical chemistry, bath release testing, biological analysis, microbiological testing, and material testing.

7 Romans Business Park, East Street Farnham, Surrey GU9 7SX United KingdomBioventix supplies and offers custom production of sheep monoclonal antibodies.

Farnham, England United KingdomBioventix supplies and offers custom production of sheep monoclonal antibodies.

Unit 9, Williams House, Manchester Science Park, Manchester, M15 6SE United KingdomBiorelate was founded in 2014 from cutting-edge scientific research into how biomedical curation can utilise existing dark knowledge to accelerate future drug discovery. Staying true to our roots, we have always believed that a better understanding of today’s science can bring forward the next generation of life-saving therapeutics being developed by world leading researchers. As the incredible progress of scientific researchers continues to compound the huge volume of growing and evolving biomedical data, Biorelate’s mission has never been so important. Through our platform, Galactic AI™, we use artificial intelligence led curation to provide and enable the insights that matter to scientists and organisations developing the innovations of the future.

The Dorothy Hodgkin Building Babraham Research Campus Cambridge, CB22 3FH United Kingdombit.bio is a synthetic biology company providing human cells for research, drug discovery and cell therapy. The company applies a patented safe harbour gene-targeting approach, optimised inducible over expression (opti-ox™), to express transcription factor combinations that reprogram human induced pluripotent stem cells (iPSCs) into highly defined and mature human cell types. The company is marketing human iPSC-derived cell types and disease models for research use, and building a clinical pipeline. The precise control of transcription factor expression in every stem cell leads to an entire culture converting to a defined cell type consistently and rapidly. This next generation precision reprogramming technology overcomes the challenges faced when using alternative cellular reprogramming methods or traditional directed differentiation, such as gene silencing, mixed cell populations, long protocol timelines, and lack of scalability. ioCells™ opti-ox enabled cells are provided cryopreserved and are ready for experimentation within a few days. Cells are easy to use with our simple two-phase protocol and require only one open-source medium. They are suitable as models for research in molecular and cell biology, disease modelling, target validation and drug screening. ioWild Type Cells™ ioGlutamatergic Neurons ioGABAergic Neurons ioMicroglia ioSkeletal Myocytes Additional cell types in development, please contact us with your requests ioDisease Model Cells™ ioDisease Model Cells are engineered to contain disease-relevant mutations. Each disease model cell can be used alongside a genetically matched wild-type control, forming an isogenic pair that enables scientists to make true comparisons in their data. Huntington’s disease ioGlutamatergic Neurons HTT 50CAG/WT ALS and frontotemporal dementia ioGlutamatergic Neurons TDP-43 M337V homozygous and heterozygous ioGlutamatergic Neurons MAPT P301S homozygous and heterozygous ioGlutamatergic Neurons MAPT N279K homozygous and heterozygous Parkinson’s and Gaucher diseases ioGlutamatergic Neurons GBA null homozygous and heterozygous ioGlutamatergic Neurons PRKN R275W homozygous and heterozygous Duchenne muscular dystrophy ioSkeletal Myocytes DMD Ex44 Deletion ioSkeletal Myocytes DMD Ex52 Deletion

Abbey Square England, RG1 3EH United KingdomBracket was created in 2011 through the merger of the Specialty Clinical Services and Clinical Technologies Group business units within United BioSource Corporation (UBC), which was acquired by pharmacy benefit manager Medco Health Solutions. Express Scripts acquired Medco Health Solutions in 2012. In August 2013, Bracket became an independent portfolio company of Parthenon Capital Partners, a Boston- and San Francisco-based growth-oriented private equity firm that provides capital and strategic resources to growing middle market companies for acquisitions and internal growth. Together, Bracket and Parthenon Capital Partners are committed to continued innovation and growth, and to providing exceptional service to our pharma, biotech and medical device industry clients.

12 Pembroke Avenue, Denny Industrial Centre Waterbeach Cambridge CB25 9QR UNITED KINGDOMBiosynergy offers antibody production, cell culture, downstream processing, and assay development.

London, England United KingdomAt Barts Health, our vision is to change lives. We are the largest NHS Trust in the UK serving a population of 2.5 million in east London and beyond. Our Trust, established on 1 April 2012, consists of five local hospital sites: Mile End Hospital, The Royal London Hospital, Newham University Hospital, St Bartholomew's Hospital and Whipps Cross University Hospital. Read more about our hospitals. Barts Health is also proud to be part of UCLPartners, Europe’s largest and strongest academic health science partnership. The objective of UCLPartners is to translate cutting edge research and innovation into measurable health gain for patients and populations through partnership across settings and sectors, and through excellence in education.

54-56 Waldegrave Road Teddington, Middlesex TW11 8NY, United KingdomButterworth Laboratories provides wet chemistry, spectroscopy, chromatography and elemental microanalysis.

Hailsham, England United KingdomBiognosis specialises in the supply of quality kits and reagents for the diagnosis of human and veterinary diseases. Our products are sourced from around the world and currently totals over 100,000 kits.

Freshwater Quarry Brixham, Devon TQ5 8BA United KingdomBrixham Environmental Laboratory offers ecotoxicology, enironmental analysis, physical and analytical chemistry analysis, and REACH services.

The Business Centre Church End Cambridge CB1 3LB United KingdomBiocair provides shipping for scientific materials.

14 Great Victoria Street, Belfast, BT2 7BA Northern IrelandBioKinetic Europe provides Phase I-III studies in various research areas, including diabetes, dermatology, and women's health.

Belfast, Northern Ireland United KingdomBioKinetic Europe provides Phase I-III studies in various research areas, including diabetes, dermatology, and women's health.

United KingdomBiochemical DIRECT supplies high purity rare biochemicals including Carbenicillin, Cefotaxime, X-Gluc, Thidiazuron and Zeatin.

St Johns Innovation Centre Cowley Rd Cambridge, Cambs, CB4 0WS United KingdomSupply and service of scientific instruments primarily for materials and surface R&D and QC

2 Marsault Court, 11 Kew Foot Road, Richmond, , London, TW9 2SS United KingdomWe provide evidence sciences services to global bio-pharmaceutical companies We service clients across the globe in following areas: Evidence planning Clinical research Health outcomes Epidemiology and RWE Scientific and Value writing

2 Royal College St Kings Cross London, NW1 0NH United KingdomThe Bio-Analysis Centre offers a Triple Quad Mass Spectrometer, two advanced HPLC instruments plus the latest High Performance label free Capillary Electrophoresis instrument from deltaDOT. With these instruments the Centre can help identify and quantitate a wide range of analytes. The Centre allows users to run their own samples on the instruments (after training) which can reduce their analysis costs and allow them to keep control of their work. The range of instruments in the Centre will be kept under review and may be extended depending on Clients’ analytical needs. The Centre is working towards being GLP compliant so that it will be able to meet a wider range of clients’ analytical requirements from that point onwards.

2 Royal College Street England, NW1 0PB United KingdomThe Bio-Analysis Centre offers a Triple Quad Mass Spectrometer, two advanced HPLC instruments plus the latest High Performance label free Capillary Electrophoresis instrument from deltaDOT. With these instruments the Centre can help identify and quantitate a wide range of analytes. The Centre allows users to run their own samples on the instruments (after training) which can reduce their analysis costs and allow them to keep control of their work. The range of instruments in the Centre will be kept under review and may be extended depending on Clients’ analytical needs. The Centre is working towards being GLP compliant so that it will be able to meet a wider range of clients’ analytical requirements from that point onwards.

Bo’Ness Road Newhouse, Lanarkshire, ML1 5UH United KingdomFounded in 2013, BioAscent is a leading provider of integrated drug discovery services based at the former Organon / MSD R&D site in Newhouse, Scotland. Our drug discovery services include de novo assay development, target analysis and bespoke screening strategies, compound screening, medicinal and synthetic chemistry, computational chemistry and compound management, all with access to a library of 125K lead-like compounds and fragments library. Our team of expert scientists has experience of successfully working from assay development through to preclinical and clinical candidates across all biological target classes and major therapeutic indications. As part of its compound management service, BioAscent currently holds and manages over 1 million compounds for our customers, in both liquid and solid formats.

Bo'Ness Road Scotland United KingdomFounded in 2013, BioAscent is a leading provider of integrated drug discovery services based at the former Organon / MSD R&D site in Newhouse, Scotland. Our drug discovery services include de novo assay development, target analysis and bespoke screening strategies, compound screening, medicinal and synthetic chemistry, computational chemistry and compound management, all with access to a library of 125K lead-like compounds and fragments library. Our team of expert scientists has experience of successfully working from assay development through to preclinical and clinical candidates across all biological target classes and major therapeutic indications. As part of its compound management service, BioAscent currently holds and manages over 1 million compounds for our customers, in both liquid and solid formats.

Pennyfoot Street Pennyfoot street England, NG1 1GF United KingdomBioMedha is a UK-based pre-clinical CRO providing in vitro biology expertise to the global drug discovery industry. We are industry-experienced, in vitro biology-focused scientists and can add significant value to our client programmes by undertaking key elements of the early stage drug discovery process

4B Highgate Business Centre 33 Greenwood Place London NW5 1LB United KingdomBioLegend strives to provide quality research reagents and expert technical support to the scientific community worldwide. We look forward to serving your research needs and becoming your long term research partner.

3 Booths Park Booths Hall Knutsford, Cheshire, WA16 8GS United KingdomFishawack Health (previously Blue Latitude Health) Blue Latitude Health is now Fishawack Health. Fishawack Health is the leading global commercialization partner for the modern life science era. Established in 2001 and headquartered in the UK, the organization is powered by a 1,300+ globe-spanning pack of strategic, creative, and scientific experts. We empower healthcare professionals and patients with the knowledge they need to live better lives. Our core operating units—Medical, Marketing, Market Access, and Consulting—bring together best-in-class capabilities from around the world. We empower our pharmaceutical, biotech, and medical technology clients to navigate the most complex of ecosystems, helping them on an effective path to develop, launch, and grow their brands, services, and portfolios. Our internationally recognized, award-winning teams collaborate across operations in the UK (Brighton, Fleet, London, Knutsford, Manchester, Oxford, and Sale), Ireland (Dublin), USA (Chicago, Evansville, Minneapolis, New York, Philadelphia, San Diego, Scottsdale, and St. Louis), Greece (Athens), and Singapore.

Crown House 72 Hammersmith Road Hammersmith London W14 8TH United KingdomBBK Worldwide provides investigator and ptient recruitment services.

Exchange Place 2 5 Semple Street Edinburgh, EH8 3BL United KingdomBBI Solutions has served the global diagnostics industry for over 50 years, as a leading developer and manufacturer of raw materials and finished test platforms for the in-vitro diagnostics market. Over the past 50 years, BBI has grown from a small specialist company, to a global business with manufacturing sites in five different countries, spanning three continents. Our product ranges include: Biological Raw Materials Antigens Enzymes Monoclonal Antibodies and Recombinant Fab Antibodies Serum & Plasma Products Depleted Serum Disease State Plasma Normal Serum and Patient Samples In addition, we manufacture world renowned labels for lateral flow, ELISA assay and biosensors, these include: Gold Nanoparticles Horseradish Peroxidase and Glucose Oxidase BBI Solutions also offers end to end Contract Development and manufacturing services, with a core focus on custom gold conjugation and lateral flow test manufacture. Innovative new projects include the integration of emerging technologies into our products, such as the Novarum Smartphone Reader. BBI Solutions is part of the BBI Group www.the-bbigroup.com

Porton Science Park Incubator Centre, Bybrook Road, Porton Down Salisbury, Wiltshire, SP4 0BF United KingdomBBI Solutions has served the global diagnostics industry for over 50 years, as a leading developer and manufacturer of raw materials and finished test platforms for the in-vitro diagnostics market. Over the past 50 years, BBI has grown from a small specialist company, to a global business with manufacturing sites in five different countries, spanning three continents. Our product ranges include: Biological Raw Materials Antigens Enzymes Monoclonal Antibodies and Recombinant Fab Antibodies Serum & Plasma Products Depleted Serum Disease State Plasma Normal Serum and Patient Samples In addition, we manufacture world renowned labels for lateral flow, ELISA assay and biosensors, these include: Gold Nanoparticles Horseradish Peroxidase and Glucose Oxidase BBI Solutions also offers end to end Contract Development and manufacturing services, with a core focus on custom gold conjugation and lateral flow test manufacture. Innovative new projects include the integration of emerging technologies into our products, such as the Novarum Smartphone Reader. BBI Solutions is part of the BBI Group www.the-bbigroup.com

Broad Oak Road, Sittingbourne, Sittingbourne, Kent, ME9 8AQ United KingdomBBI Solutions has served the global diagnostics industry for over 50 years, as a leading developer and manufacturer of raw materials and finished test platforms for the in-vitro diagnostics market. Over the past 50 years, BBI has grown from a small specialist company, to a global business with manufacturing sites in five different countries, spanning three continents. Our product ranges include: Biological Raw Materials Antigens Enzymes Monoclonal Antibodies and Recombinant Fab Antibodies Serum & Plasma Products Depleted Serum Disease State Plasma Normal Serum and Patient Samples In addition, we manufacture world renowned labels for lateral flow, ELISA assay and biosensors, these include: Gold Nanoparticles Horseradish Peroxidase and Glucose Oxidase BBI Solutions also offers end to end Contract Development and manufacturing services, with a core focus on custom gold conjugation and lateral flow test manufacture. Innovative new projects include the integration of emerging technologies into our products, such as the Novarum Smartphone Reader. BBI Solutions is part of the BBI Group www.the-bbigroup.com

BBI Solutions Unit 2 Parkway, Pen-y-Fan, Industrial Estate Crumlin, NP11 3EF United KingdomBBI Solutions has served the global diagnostics industry for over 50 years, as a leading developer and manufacturer of raw materials and finished test platforms for the in-vitro diagnostics market. Over the past 50 years, BBI has grown from a small specialist company, to a global business with manufacturing sites in five different countries, spanning three continents. Our product ranges include: Biological Raw Materials Antigens Enzymes Monoclonal Antibodies and Recombinant Fab Antibodies Serum & Plasma Products Depleted Serum Disease State Plasma Normal Serum and Patient Samples In addition, we manufacture world renowned labels for lateral flow, ELISA assay and biosensors, these include: Gold Nanoparticles Horseradish Peroxidase and Glucose Oxidase BBI Solutions also offers end to end Contract Development and manufacturing services, with a core focus on custom gold conjugation and lateral flow test manufacture. Innovative new projects include the integration of emerging technologies into our products, such as the Novarum Smartphone Reader. BBI Solutions is part of the BBI Group www.the-bbigroup.com

Kelvin Walkway Todd Campus, West of Scotland Science Park, Acre Road Scotland, G20 0SP United KingdomREPROCELL Europe offers the full range of translational research products and services of the ReproCELL Group to Europe, Middle East and Africa (EMEA). Through our ongoing research and development synergy we are bringing to market unique and competitive products and services to accelerate research in stem cells, human tissues and 3D cell culture.

Thomson Pavilion, Todd Campus West of Scotland Science Park, Acre Road Glasgow, Scotland, G20 0XA United KingdomREPROCELL Europe offers the full range of translational research products and services of the ReproCELL Group to Europe, Middle East and Africa (EMEA). Through our ongoing research and development synergy we are bringing to market unique and competitive products and services to accelerate research in stem cells, human tissues and 3D cell culture.

15 Hostmoor Ave March, Cambridgeshire PE15, UKBioProgress Technology offers an array of enabling systems for the food, medical and pharmaceutical industries.

England United KingdomBioProgress Technology offers an array of enabling systems for the food, medical and pharmaceutical industries.

Bloodwise, 39-40 Eagle Street, London, WC1R 4THCell Bank is a national collection of samples from patients with paediatric haematological malignancies. Samples include live cells from bone marrow, plasma from peripheral blood and CSF. The Bank also holds a collection of HLA typed cord blood. The Bloodwise CellBank is comprised of samples donated by children diagnosed with leukaemia in the UK. These samples are available for use in research into childhood leukaemia. UK-based researchers can apply to use samples from CellBank for peer-reviewed and fully-costed research projects.

Biopharma House, Winnall Valley Road, Winchester SO23 0LD, United KingdomBiopharma Technology offers formulation analysis for lyophilisation, lyophilisation development, and freeze-dryers.

Adam House, 1st Floor 1 Fitzroy Square London, W1T5HE United KingdomBostwick Laboratories provides anatomic and clinical pathology laboratory services specializing in the monitoring and diagnosis of cancer.

36 Cowley Crescent Bradford West Yorkshire BD9 6LXBioSupply UK offers antibodies, assays, kits, and recombinant proteins for purchase.

United KingdomBioSupply UK offers antibodies, assays, kits, and recombinant proteins for purchase.

Loughborough Innovation Centre Charnwood Building Holywell Park Ashby Road Loughborough, LE11 3AQBy the application of pharmacometric principles, and PKPD modelling and simulation we aim to add value to the projects of our customers, and guide their decisions with quantitative evidence.

91 Milton Park Abingdon Oxfordshire OX14 4RY UKBioAnalab offers assay development services, immunogenicity assays, vaccine services and pharmacokinetic/toxicokinetic services.

Oxford, England United KingdomBioAnalab offers assay development services, immunogenicity assays, vaccine services and pharmacokinetic/toxicokinetic services.

Breast Cancer Now, Fifth floor, Ibex House, 42-47 Minories, London EC3N 1DYThe BCNTB is a unique initiative designed for the breast cancer research community. It is a collection of well-characterised, validated clinical material including tissue (tumour and normal) in a variety of formats, blood, cells and other derivatives, matched with clinical information.

Silvaco Technology Centre Compass Point, St. Ives, Cambridgeshire PE27 5JL United KingdomBacklogs is the UK division of Online Pathology Services and offers internet pathology services to specifically address the difficulties of recruitment currently encountered by pathology departments in the UK.

Slough, England United KingdomA specialist clinical trial supplier of comparator drugs with a global reach

St Julians, Sevenoaks Kent, TN15 0RX United KingdomBethyl Laboratories provides antibody products and services for both clinical and research applications.

Bio-Imaging Centre, Basement Medical Block, Within Glasgow Royal Infirmary, 84 Castle Street, Glasgow, UK, G4 0SFBio-Images Research are experts in scintigraphic clinical trials on drug delivery systems.

Glasgow, Scotland United KingdomBio-Images Research are experts in scintigraphic clinical trials on drug delivery systems.

Broadwater Road Welwyn Garden City, England United KingdomLocated close to the heart of London's biomedical technology community, BioPark provides specialist facilities and support for bioscience and health technology businesses, encouraging growth and the development of new products and technologies.

Charterhouse Square London, England, EC1M United KingdomThe Flow Cytometry Core Facility aim is to provide high quality professional service related to flow cytometric techniques using cutting edge equipment. To achieve this goal, we encourage interaction between users and lab members of the core facility.
 Support and training is provided for the use of all analysers, help is provided in experiment design, data interpretation, presentation and troubleshooting. A full sorting service is also provided. Equipment The lab is equipped with the following flow cytometers: - Three Becton Dickinson LSR Fortessa - One Becton Dickinson FACSCalibur, - One Amnis/Merck ImageStream X Mark II, - Two Becton Dickinson ARIA cell sorters. - We also have a CyTOF2 Mass Cytometer

Cefn Coed, Parc Nantgarw, Cardiff, CF15 7QQ, Wales, UKBiocatalysts offers enzymes for purchase and contract fermentation services.

Cefn Coed Parc Nantgarw Cardiff, Wales, CF15 7QQ United KingdomBiocatalysts offers enzymes for purchase and contract fermentation services.

8 Calthorpe Road Edgbaston, Birmingham B15 1QT United KingdomBinding Site is a Specialist Protein company committed to the research, development, manufacture and distribution of innovative immunodiagnostic assays for the global laboratory market.

8 Calthorpe Road Edgbaston, Birmingham, B15 1QT United KingdomBinding Site is a Specialist Protein company committed to the research, development, manufacture and distribution of innovative immunodiagnostic assays for the global laboratory market.

1030 Eskdale Road Winnersh Triangle WOKINGHAM, United Kingdom, RG41 5TS United Kingdom

1030 Eskdale Road Winnersh Triangle WOKINGHAM, United Kingdom, RG41 5TS United Kingdom

1030 Eskdale Road Winnersh Triangle WOKINGHAM, United Kingdom, RG41 5TS United Kingdom

Teaching & Learning Centre, Queen Elizabeth University Hospital 1345 Govan Road Glasgow, UK, G51 4TF United KingdomBioClavis is a Glasgow-based spin-out of BioSpyder technologies leveraging the powerful TempO-Seq transcriptomic/genomic platform technology for personalised diagnostics and drug discovery. TempO-Seq is a high-throughput assay specifically designed for very efficient profiling of molecular signatures or transcriptomes from limited sample amounts including FFPE sections, tissue microarrays, or fine needle aspirates. Multiplexing is unlimited, ranging from tens to thousands of genes/SNPs to whole transcriptome at a fraction of the cost of RNA-Seq. Importantly, due to the lack of purification and reverse transcription steps, TempO-Seq excels where traditional techniques fail: low input, RNA degradation, or formalin fixation have negligible impact on performance. Data is delivered in a standard format compatible with essentially any secondary analysis pipelines such as CMap or BMDExpress, and we offer bioinformatics support to help you make sense of the data. TempO-Seq therefore enables efficient, sensitive, and inexpensive profiling of both in vitro and in vivo samples or patient cohorts at a large scale, and BioClavis can work with you to implement molecular endpoints in your high-throughput studies.

Magdalen Centre, Oxford Science park Robert Robinson Avenue Oxford, Oxfordshire, OX4 4GA United KingdomATDBio founded in 2005 by Prof. Tom Brown, a leading nucleic acid chemist, is now a part of Biotage. We are experts in oligonucleotide synthesis for therapeutic applications: ASOs, siRNA, RNAi, Aptamers, new chemical modalities.

University of Southampton University Rd Southampton , SO17 1BJ United KingdomATDBio founded in 2005 by Prof. Tom Brown, a leading nucleic acid chemist, is now a part of Biotage. We are experts in oligonucleotide synthesis for therapeutic applications: ASOs, siRNA, RNAi, Aptamers, new chemical modalities.

Distribution Way Dyffryn Business Park Ystrad Mynach Hengoed CF82 7TS United KingdomATDBio founded in 2005 by Prof. Tom Brown, a leading nucleic acid chemist, is now a part of Biotage. We are experts in oligonucleotide synthesis for therapeutic applications: ASOs, siRNA, RNAi, Aptamers, new chemical modalities.

BioCity Scotland Bo'ness Road Motherwell, Scotland, ML1 5UH United KingdomFor more than 20 years BDD have developed and grown a world leading platform of expertise in biopharmaceutics and oral drug formulation development. We can provide both formulation development services and clinical testing to streamline the development process. Through the undertaking of a wide variety of clinical trials in which we have visualised the performance of products, we are able to identify and anticipate drug delivery challenges and apply this knowledge to our formulation development from an early stage. This ensures our clients take a reliable path to commercial success.

Basement Medical Block, Within Glasgow Royal Infirmary 84 Castle Street Glasgow, G4 0SF United KingdomFor more than 20 years BDD have developed and grown a world leading platform of expertise in biopharmaceutics and oral drug formulation development. We can provide both formulation development services and clinical testing to streamline the development process. Through the undertaking of a wide variety of clinical trials in which we have visualised the performance of products, we are able to identify and anticipate drug delivery challenges and apply this knowledge to our formulation development from an early stage. This ensures our clients take a reliable path to commercial success.

Basement Medical Block, Within Glasgow Royal Infirmary 84 Castle Street Glasgow, G4 0SF United KingdomFor more than 20 years BDD have developed and grown a world leading platform of expertise in biopharmaceutics and oral drug formulation development. We can provide both formulation development services and clinical testing to streamline the development process. Through the undertaking of a wide variety of clinical trials in which we have visualised the performance of products, we are able to identify and anticipate drug delivery challenges and apply this knowledge to our formulation development from an early stage. This ensures our clients take a reliable path to commercial success.

1030 Eskdale Road Winnersh Triangle WOKINGHAM, United Kingdom, RG41 5TS United KingdomBD Biosciences offers ADME/Tox services, cell analysis and reagent services, bioprocessing media and supplement services, custom coating services and microplate barcoding services.

Innovation Park Hillfoots Road Stirling FK9 4NF ScotlandBioReliance® is a brand business within the wider Merck KGaA, Darmstadt, Germany group. There are six franchises with the brand offering a wide range of services to support the Life Science Market; 1) BioReliance® Biosafety Testing Services, which provides Biologics Safety Testing, Biomanufacturing Services (Mammalian Cell Bank), Viral Clearance Studies and Lot Release testing of clinical and commercial material (bulk harvest, Drug substance and Drug Product) 2) BioReliance® Product Characterization Services, which provide product and process characterization services including physicochemical assays, binding and potency assays 3) BioReliance® Validation Testing Services providing validation services for selecting, testing and validating filters, assemblies and single-use systems for drug manufacturing. Services include Extractables and leachables testing, Bacteria retention testing, Integrity testing, Compatibility testing & Patient safety evaluations 4) BioReliance® End to End Services providing manufacturing services to accelerate clinical drug development, scale your process and implement local production facilities, globally. 5) BioReliance® Viral Vector Manufacturing provide contract manufacturing services for virus and gene therapy molecules

Todd Campus West of Scotland Science Park Glasgow G20 0XA ScotlandBioReliance® is a brand business within the wider Merck KGaA, Darmstadt, Germany group. There are six franchises with the brand offering a wide range of services to support the Life Science Market; 1) BioReliance® Biosafety Testing Services, which provides Biologics Safety Testing, Biomanufacturing Services (Mammalian Cell Bank), Viral Clearance Studies and Lot Release testing of clinical and commercial material (bulk harvest, Drug substance and Drug Product) 2) BioReliance® Product Characterization Services, which provide product and process characterization services including physicochemical assays, binding and potency assays 3) BioReliance® Validation Testing Services providing validation services for selecting, testing and validating filters, assemblies and single-use systems for drug manufacturing. Services include Extractables and leachables testing, Bacteria retention testing, Integrity testing, Compatibility testing & Patient safety evaluations 4) BioReliance® End to End Services providing manufacturing services to accelerate clinical drug development, scale your process and implement local production facilities, globally. 5) BioReliance® Viral Vector Manufacturing provide contract manufacturing services for virus and gene therapy molecules

Brunswick House, The Bridge Business Centre, Beresford Way, Chesterfield S41 9FGCK Aspire is a Contract Research Organisation (CRO) and Research Services company that specialises in Real-World Evidence Studies. We are probably best known for the being the operational partner on the Salford Lung Study with GSK. CK Aspire is a trading name of CK Associates, part of the CK Group.

CK Aspire, Brunswick House, The Bridge Business Centre Beresford Way Chesterfield, Derbyshire, S41 9FG United KingdomCK Aspire is a Contract Research Organisation (CRO) and Research Services company that specialises in Real-World Evidence Studies. We are probably best known for the being the operational partner on the Salford Lung Study with GSK. CK Aspire is a trading name of CK Associates, part of the CK Group.

CBTC2 Capital Business Park Wentloog Cardiff, CF32PX United KingdomCatSci is an award-winning process research and development CRO that provides perfect-for-purpose chemistry services and non-GMP material supply to emerging, mid-sized and large pharma. We proudly serve customers across the globe delivering projects from lead optimisation through to product launch and life-cycle management. As an independent, scientifically-unbiased and commercially-minded CRO, CatSci is dedicated to understanding and optimising your chemical reactions and manufacturing processes. Favouring a consultative approach, we take the time to understand your project objectives to design and deliver tailored solutions to match your specific demands. Our large pharma pedigree and extensive experience working on small molecule drug discovery and development projects mean that we can expedite your candidate selection, route design, process scale-up and optimisation. Non-GMP material supply from milligrams to kilograms is conveniently carried out in our laboratory, whilst for larger quantities and/or GMP manufacture, we are able to work with our trusted partners or your preferred supplier.

London, England United KingdomCENTUVA provides efficient and cost-effective MD and PhD contract services right across the industry. Our experienced team of MDs and PhDs work with Marketing/Sales and Medical Affairs departments across North America and Europe. We work on demand with pharmaceutical, medical device and medical diagnostics companies through a personalized approach. We offer several services including our award-winning Doctors Speaking With Doctors. See our service offer at www.centuva.com. Centuva’s unparalleled access to the medical community, expertise, value and credibility lets you target your markets, build ongoing dialogue and achieve your goals.

West Midlands Regional Genetics Laboratory Birmingham Women’s NHS Foundation Trust Mindelsohn Way Edgbaston Birmingham B15 2TGThe Central England Haemato-Oncology and Oncology Research Biobank (CEHRB) predominantly stores excess material from haemato-oncology and oncology samples referred for diagnostic testing and disease monitoring at the West Midlands Regional Genetics Laboratory (WMRGL). Haemato-oncology samples are stored at presentation and throughout the disease course, including at remission and relapse. In addition CEHRB stores haemato-oncology and oncology samples which are specifically taken for the biobank, usually in response to a specific project.

Heath Park, Cardiff, CF14 4XY UKWe are the only dental school in Wales, providing unique and important leadership in dental research, teaching and patient care. We are located at the University Dental Hospital on Cardiff University's Heath Park campus, a 53 acre site shared with the University Hospital of Wales. Progressive healthcare education and patient care are successfully integrated with our research facilities in this major teaching and research centre. Our academic and clinical staff are recognised as being world-leading experts in their fields. They provide valuable clinical services to the people of Wales in addition to their academic responsibilities.

Stephenson Building Keele Science Park Keele, ST5 5SP United Kingdom, EuropeCobra Biologics provides cell line development, virus products, strain development, process development, and cGMP manufacturing.

Stephenson Building The Science Park Keele, ST5 5SP United KingdomCobra Biologics provides cell line development, virus products, strain development, process development, and cGMP manufacturing.

53 Portland Street England, M1 3LD United KingdomC4X Discovery was formed as a spin-out from the University of Manchester in 2008 and is focused on the optimisation of drug discovery and design. It uses its NMR-based technology to accurately solve the bioactive three-dimensional structures of molecules independently of techniques such as X-ray crystallography and computational chemistry. As well as working in partnership with the pharmaceutical industry, C4X Discovery is applying its technology to high-value therapeutic targets to generate proprietary drug candidates and intellectual property.

200 Western Avenue Cardiff, Wales, CF5 2YB United Kingdom

Centre for Integrated Genomic Medical Research (CIGMR) Faculty of Medical and Human Sciences University of Manchester Stopford Building Oxford Road Manchester M13 9PTCIGMR Biobank is an automated, ISO 9001:2008 certified sample management infrastructure designed to support health related research and translational medicine. Our facility within Manchester Medical School is capable of processing hundreds of biological samples each day for storage or for immediate analysis. We process a range of sample types including blood, urine, sputum, synovial fluid and saliva. We are experienced in conducting large sample collection projects for genetic epidemiology experiments such as GWAS, deep sequencing, candidate gene analysis, proteomic, transcriptomic and metabolomic experiments. CIGMR Biobank supports a number of Manchester-led collaborative research projects requiring large numbers of biological samples for analysis e.g. the EU FP7 REQUITE project lead by Professor Catherine West which aims to predict which patients develop side effects from radiotherapy. The Biobank also manages sample collections for a number of nationally important collections e.g. The Motor Neurone Disease Association DNA Bank. This collection contains the largest number of biological samples gifted by people with MND for research in the UK. For a list of the collections we manage and facilitate please click here. CIGMR Biobank also works closely with NHS health partners within the Manchester Academic Health Science Centre (MAHSC) in the area of sample management and has established shared sample tracking and quality assurance (ISO 9001:2008) systems with Salford Royal NHS Foundation Trust.

One St Colme Street Edinburgh EH3 6AA UKWe are a leading provider of market research and consultancy services in the crop protection and biotechnology sectors. As part of Wood Mackenzie, we introduced our first product, the Agrochemical Service, in 1977. The Service went on to become the foremost source of data and analyses on the global agrochemical industry. Since the middle of the 1990s, the Service has also covered the commercial aspects of the rapidly expanding agricultural biotechnology sector. In 1994, we expanded our offerings with the introduction of a suite of databases, which complement the Service by offering a detailed sales breakdown on all aspects of the crop protection market. We also provide a range of strategic consultancy services, utilising our deep foundation of knowledge to offer advice to the industry and associated organisations. The Cropnosis business has had a varied history under the ownership of Wood Mackenzie. Originally a stockbroking firm, Wood Mackenize was acquired by the NatWest Bank Group in 1988. In 1998, the business, together with the Equities division, was sold to Bankers Trust International. Banker's Trust was in turn acquired by Deutsche Bank in 1999. At the end of 2001, Wood Mackenzie regained its independence via an employee buyout. As an extension of this, the crop protection division was bought by its staff on 1st August 2003 and transferred to an independent company named Cropnosis. As a totally independent company, focussed only on crop protection and biotechnology, Cropnosis is more able to service changing industry needs. At the same time, we aim to maintain the market leadership and high standard of quality for which we are renowned.

9 Roffords Goldsworth Park, Surrey, GU21 3BH United KingdomAt Cope Pharma Consultancy, we provide a service tailored to your company’s requirements. Working closely with our clients, we can deliver a friendly, efficient and cost-effective service for both Human Pharma and Veterinary Products. We have considerable experience in the GMP auditing of CMOs, CROs, APIs, Raw Materials, Excipients, Medical Devices and Packaging Materials. We have extensive expertise in stability report writing and the preparation of CMC documentation.

Penrhyn Road, Knowsley Business Park Prescot, Merseyside L34 9HY UK,Contract Chemicals offers liquids and solid handling, waste treatment, analytical facilities, and compound production.

Knowsley, England United KingdomContract Chemicals offers liquids and solid handling, waste treatment, analytical facilities, and compound production.

The Merrifield Centre Rosemary Lane Cambridge CB1 3LQCambridge Discovery Chemistry provides innovative chemistry services to accelerate discovery and process research, serving the pharmaceutical, agrochemical and biotechnology industries.

Imperial House, Oaklands Business Centre Oaklands Park, Wokingham Berkshire , RG41 2FD United KingdomCEM Analytical Services offers residue analysis, pharmaceutical analysis, REACH testing, formulation development, bioanalysis, and ecotoxicology studies.

407 St John Street London EC1V 4AD

14 New Bond Street Bath, England, BA1 1BE United KingdomOur mission is to HELP scientists and we are always looking for MORE commercial and academic antibodies to make CiteAb better.

Nottingham, UKCellAura Technologies provides microscopy, fluorescent ligand binding, screening services, fluorescence-based services, and dual readout binding and function.

BioCity Pennyfoot Street Nottinghamd NG1 1GF UKCellAura Technologies provides microscopy, fluorescent ligand binding, screening services, fluorescence-based services, and dual readout binding and function.

Cheadle Royal Business Park - Highfield Cheadle SK8 3GY - United KingdomChiesi farmaceutici offers drug development, drug discovery, and clinical trials.

8 Tennis Court Road University of Cambridge, 8 Tennis Court Road England, CB2 1QW United KingdomSpin-out from the Farndale Lab in University of Cambridge, designed to take forward the manufacture and supply of collagen peptides to academia and the pharma industry. CambCol Laboratories is a new venture, that was established to transfer the peptide synthesis facility and related interests of the Farndale Lab in Biochemistry at the University of Cambridge into a new, commercial entity. The core business of CambCol Laboratories is the synthesis and distribution of collagen-like, triple helical peptides and platelet-related materials. These have been developed over 20 years of research in the “Farndale Lab” in Cambridge and are supplied to over 100 laboratories worldwide to underpin diverse basic and clinical research projects in thrombosis and haemostasis in academic and commercial settings for many years. The range is under constant review and continuous expansion and the company also offers a “bespoke” peptide synthesis service where required.

15 Station Road, Wilburton England, CB7 4DL United KingdomSpin-out from the Farndale Lab in University of Cambridge, designed to take forward the manufacture and supply of collagen peptides to academia and the pharma industry. CambCol Laboratories is a new venture, that was established to transfer the peptide synthesis facility and related interests of the Farndale Lab in Biochemistry at the University of Cambridge into a new, commercial entity. The core business of CambCol Laboratories is the synthesis and distribution of collagen-like, triple helical peptides and platelet-related materials. These have been developed over 20 years of research in the “Farndale Lab” in Cambridge and are supplied to over 100 laboratories worldwide to underpin diverse basic and clinical research projects in thrombosis and haemostasis in academic and commercial settings for many years. The range is under constant review and continuous expansion and the company also offers a “bespoke” peptide synthesis service where required.

17 Oak Lane Oak Lane, Littleport Littleport, England, CB6 1RS United KingdomSpin-out from the Farndale Lab in University of Cambridge, designed to take forward the manufacture and supply of collagen peptides to academia and the pharma industry. CambCol Laboratories is a new venture, that was established to transfer the peptide synthesis facility and related interests of the Farndale Lab in Biochemistry at the University of Cambridge into a new, commercial entity. The core business of CambCol Laboratories is the synthesis and distribution of collagen-like, triple helical peptides and platelet-related materials. These have been developed over 20 years of research in the “Farndale Lab” in Cambridge and are supplied to over 100 laboratories worldwide to underpin diverse basic and clinical research projects in thrombosis and haemostasis in academic and commercial settings for many years. The range is under constant review and continuous expansion and the company also offers a “bespoke” peptide synthesis service where required.

London, UKCarbone scientific is located at London, UK. We are mainly engaged in the marketing development, R &D, technical support and service. Carbone scientific provides fine chemicals, pharmaceutical intermediates, and active pharmaceutical ingredients to the global marketplaces. Our aim is to make those most popular products available to these pharmaceutical and biotech companies, research organizations and university labs worldwide. Our online catalogue has already listed over 50,000 products and over 6000 products in stock. Any customers could be easily to select any products from our online catalogue for creating purchase orders. The very competitive price and lead time information are available for you after you register at our web site.

SUITE LG01, CHANCERY HOUSE CHANCERY LANE London, WC2A 1QU United KingdomCarbone scientific is located at London, UK. We are mainly engaged in the marketing development, R &D, technical support and service. Carbone scientific provides fine chemicals, pharmaceutical intermediates, and active pharmaceutical ingredients to the global marketplaces. Our aim is to make those most popular products available to these pharmaceutical and biotech companies, research organizations and university labs worldwide. Our online catalogue has already listed over 50,000 products and over 6000 products in stock. Any customers could be easily to select any products from our online catalogue for creating purchase orders. The very competitive price and lead time information are available for you after you register at our web site.

1 PHILIP VICTOR ROAD BIRMINGHAM WEST MIDLANDS B20 2QB, UKCambridge Peptides offers protein and peptide synthesis, sequencing and characterization services.

Laboratory 101 The Heath Business & Technical Park Runcorn, Cheshire, WA7 4QX United KingdomCryoniss provide a comprehensive storage service for biological samples and medicinal products from ambient, +4 °C, -20 °C, -80 °C, and vapour phase liquid nitrogen. We provide our services to customers conducting scientific research and have a wealth of experience in supporting drug discovery projects from early stage target identification through to clinical trials and life cycle management. Working to the principles of GLP, GCP, alongside being Good Distribution Practice compliant, Cryoniss delivers the highest standard of service, with next-day access to samples as standard alongside end-to-end cold chain management services. Cryoniss’ Quality Management System is accredited by the Human Tissue Authority, Animal and Plant Health Agency, Health and Safety Executive, Medicines and Healthcare products Regulatory Agency, alongside being ISO 9001 and Cyber Essentials Plus certified.

Mereside Alderley Park Macclesfield, Cheshire, SK10 4TG United KingdomCryoniss provide a comprehensive storage service for biological samples and medicinal products from ambient, +4 °C, -20 °C, -80 °C, and vapour phase liquid nitrogen. We provide our services to customers conducting scientific research and have a wealth of experience in supporting drug discovery projects from early stage target identification through to clinical trials and life cycle management. Working to the principles of GLP, GCP, alongside being Good Distribution Practice compliant, Cryoniss delivers the highest standard of service, with next-day access to samples as standard alongside end-to-end cold chain management services. Cryoniss’ Quality Management System is accredited by the Human Tissue Authority, Animal and Plant Health Agency, Health and Safety Executive, Medicines and Healthcare products Regulatory Agency, alongside being ISO 9001 and Cyber Essentials Plus certified.

14G4 Mereside Alderley Park Macclesfield, Cheshire, SK10 4TG United KingdomCryoniss provide a comprehensive storage service for biological samples and medicinal products from ambient, +4 °C, -20 °C, -80 °C, and vapour phase liquid nitrogen. We provide our services to customers conducting scientific research and have a wealth of experience in supporting drug discovery projects from early stage target identification through to clinical trials and life cycle management. Working to the principles of GLP, GCP, alongside being Good Distribution Practice compliant, Cryoniss delivers the highest standard of service, with next-day access to samples as standard alongside end-to-end cold chain management services. Cryoniss’ Quality Management System is accredited by the Human Tissue Authority, Animal and Plant Health Agency, Health and Safety Executive, Medicines and Healthcare products Regulatory Agency, alongside being ISO 9001 and Cyber Essentials Plus certified.

Cambridge Protein Arrays Ltd. MAIA Building, Babraham Research Campus Cambridge, England, CB22 3AT, UK United KingdomCambridge Protein Arrays offers proteome array research products and custom screening services. We supply the up-to-date HuProt™ Human Proteome Microarrays v3.1, the most extensive array of human proteins available on the market, containing 20,000 proteins on one slide. Our services are tailored to customer requirements and include quality control and profiling of antibody specificity, autoantibody target discovery and protein interactomics.

10 Colwick Quays Business Park Private Road no.2, Colwick Nottingham, Nottinghamshire, NG4 2JY United KingdomCellomatics BioSciences (www.cellomaticsbio.com) provide preclinical in vitro research platforms to support drug development programmes of Biotech and Pharmaceutical companies in; Oncology, Immuno-oncology, Immunological and Inflammatory disease, Respiratory, Autoimmune, Cardiovascular and Metabolic disease. Our expertise lies in providing a range of assays including immunoassays, cell based functional assays including but not limited to target validation & qualification, biomarker qualification, toxicity, cell proliferation, migration, invasion, angiogenesis, vascular permeability using either 2D or 3D cell culture models. We have a team of experienced and qualified scientists who can understand your needs and deliver innovative and practical solutions.

Biocity, Nottingham Pennyfoot Street Nottingham, Nottinghamshire, NG1 1GF United KingdomCellomatics BioSciences (www.cellomaticsbio.com) provide preclinical in vitro research platforms to support drug development programmes of Biotech and Pharmaceutical companies in; Oncology, Immuno-oncology, Immunological and Inflammatory disease, Respiratory, Autoimmune, Cardiovascular and Metabolic disease. Our expertise lies in providing a range of assays including immunoassays, cell based functional assays including but not limited to target validation & qualification, biomarker qualification, toxicity, cell proliferation, migration, invasion, angiogenesis, vascular permeability using either 2D or 3D cell culture models. We have a team of experienced and qualified scientists who can understand your needs and deliver innovative and practical solutions.

119-122 Pennyfoot Street Biocity England, NG1 1GF United KingdomCellomatics BioSciences (www.cellomaticsbio.com) provide preclinical in vitro research platforms to support drug development programmes of Biotech and Pharmaceutical companies in; Oncology, Immuno-oncology, Immunological and Inflammatory disease, Respiratory, Autoimmune, Cardiovascular and Metabolic disease. Our expertise lies in providing a range of assays including immunoassays, cell based functional assays including but not limited to target validation & qualification, biomarker qualification, toxicity, cell proliferation, migration, invasion, angiogenesis, vascular permeability using either 2D or 3D cell culture models. We have a team of experienced and qualified scientists who can understand your needs and deliver innovative and practical solutions.

Pennyfoot Street Biocity, England, NG1 1GF United KingdomCellomatics BioSciences (www.cellomaticsbio.com) provide preclinical in vitro research platforms to support drug development programmes of Biotech and Pharmaceutical companies in; Oncology, Immuno-oncology, Immunological and Inflammatory disease, Respiratory, Autoimmune, Cardiovascular and Metabolic disease. Our expertise lies in providing a range of assays including immunoassays, cell based functional assays including but not limited to target validation & qualification, biomarker qualification, toxicity, cell proliferation, migration, invasion, angiogenesis, vascular permeability using either 2D or 3D cell culture models. We have a team of experienced and qualified scientists who can understand your needs and deliver innovative and practical solutions.

12 Rosemary Lane Cambridge CB1 3LQCancer Research Technology offers translational development and commercialization with its primary focus on cancer.

University College London The Cruciform Building Gower Street London, WC1E 6BT, UKCancer Research Technology offers translational development and commercialization with its primary focus on cancer.

Angel Building 407 St John Street London EC1V 4AD, UKCancer Research Technology offers translational development and commercialization with its primary focus on cancer.

London, England United KingdomCancer Research Technology offers translational development and commercialization with its primary focus on cancer.

171 Bath Road, Slough Berkshire, SL1 4AA U.K.Chiltern International offers clinical development, biometrics, and pharmacology for the central nervous system, oncology, opthalmology, and pediatrics.

Chairman’s office, Biomedicine West, International Centre for Life, Times Square, NEWCASTLE NE1 4EP United KingdomCels Business Services Ltd (CBSL) is a focused team of partners with a cumulative 75 years’ experience of creating value in a range of life science and healthcare sectors. The partners and associates have an in-depth knowledge of the pharmaceuticals, medical biotechnology and medical technology industries.

Holmwood - Broadlands Business Campus Langhurstwood Road Horsham RH12 4QP United KingdomCmed Research provides clinical services for a wide range of therapeutic areas.

Cambridge University Tennis Court Road Cambridge CB2 1QP, UKCambridge Genomic Services offers gene expression profiling, SNP genotyping, methylation analysis, bioinformatics, and slide printing services.

Cambridge, England United KingdomCambridge Genomic Services offers gene expression profiling, SNP genotyping, methylation analysis, bioinformatics, and slide printing services.

Cranfield Bedfordshire MK43 0AL United KingdomPostharvest Biology and Technology houses the Plant Science Laboratory which is one of the largest centres dedicated to research, consultancy and education in postharvest biology and technology of fresh produce in Europe. Since our establishment in 2002 we continue to grow our research in terms of revenue, national and international reputation and scientific excellence. We service all sectors of the fresh produce supply chain including many of the major multinational food companies, multiple food retailers and undertake research for both national and international Governments, research councils, multinationals and various grower levy bodies. Key research areas Fundamental postharvest physiology and biochemistry of fresh produce Targeted and non-targeted metabolomics Technology development for reducing waste and extending storage, shelf- and home-life of fresh produce Sensor and product development (including packaging).

Unit 5 Canal Terrace Worksop, Nottinghamshire S80 2DF United KingdomChemivate offers innovative and diverse chemical compound libraries for sale to pharmaceutical and biotechnology companies for lead discovery. Chemivate also offers services to support the optimisation and development of these compounds into drug candidates.

Cranfield Bedfordshire MK43 0AL United KingdomThe mission of the Applied Mycology and Predictive Microbiology Group is to understand the effect of environmental factors on the physiology of economically important microbes, particularly fungi, and to exploit these understandings for the food, environment and health sectors.

School of Medicine Cardiff University Heath Park Cardiff CF14 4XN United KingdomCardiff University provides proteomics, confocal microscopy, flow cytometry, genomics, histology, and laser capture microdissection.

200 Western Avenue Cardiff, Wales, CF5 2YB United Kingdom

Hanwell, London, UKCole-Parmer offers laboratory and industrial fluid handling products, instrumentation, equipment, and supplies.

20 Mastmaker Road England, E14 9UB United KingdomCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

7 Old Station Business Park - Compton - Berkshire - RG20 6NE - UKCMS Chemicals provides products in the fields of carbohydrates and nucleosides for life science research.

England United KingdomCMS Chemicals provides products in the fields of carbohydrates and nucleosides for life science research.

Cambridge, UKChiral Quest offers custom synthesis, process development, intermediates, custom synthesis, and chiral products.

Kidlington, Oxfordshire, UKChiralabs provides contract expert chemical, biochemical, spectroscopic and physical analysis services and undertakes investigative, problem-solving studies of substances and products in a wide range of fields, including for the consumer, pharmaceutical, biopharmaceutical, biotechnology, health, nutrition, food, plastics, chemical, engineering and waste industries. We frequently investigate "unusual" or "unknown" materials. As well as routine analysis, we perform complex, multi-faceted investigations of challenging problems. We are world-leading experts in chirality, circular dichroism, optical spectroscopies, crystallization, biopharmaceutical structure and multi-technique analysis. Where required, we develop new approaches to solve problems. Home of BioSpecXL(TM), a comprehensive spectroscopic profile of a biopharmaceutical for product development, formulation & comparability studies and SuperSpectraXL(TM), a multi-technique megavariate method of characterizing substances, distinguishing production issues, predicting properties and making objective batch & product comparisons.

50, Llwyn-Y-Mor Court Caswell Road, Caswell Swansea UK, SA3 4RDCLC Bio provides bioinformatics and sequencing services.

Northampton, UKChemspeed Technologies is the leading provider of high-throughput and high-output research & development workflow-solutions from single bench-top/standalone automated workstations (powder dispensing – sample preparation – synthesis – process development – formulation – application – testing) up to complete and integrated product development workflows for the entire product development processes in the chemical, material science, renewables & energy, pharmaceutical, agrochemical, specialty chemical, home care, cosmetics and nutrition industries, as well as academia.

The Stables, Somerset House, Church Road, Tormarton, Badminton, GL9 1HT, United KingdomWelcome to Caleb Management Services Limited. We are an international multi-disciplinary consultancy based in Tormarton (near Bristol, England), with representation in the US. We are a networking business, well-integrated in the various policy and practice groups within our chosen business areas, and enjoy a close working relationship with our industrial clients. Caleb specialises in chemicals risk assessment, including REACH and CLP, and sustainability and environmental services. The company began as a one man operation in 1994. As a result of our successes, the company continues to grow and expand its resources. We currently have over 12 members of staff. Of these, six work solely on chemicals regulation including REACH, two work on sustainability and environmental services, and the rest support both. We have a clear policy of only growing by the direct employment of like-minded, committed people. Our People explains who we are and our specific areas of expertise. We take our inspiration from Caleb, a character in the Old Testament, who had the foresight to see that the Promised Land was within easy reach 40 years before his compatriots. They were not able to overcome their fear of the unknown, coupled with their anxiety about change, and suffered unnecessarily for 40 years as a consequence. While we may not aspire to a 40 year vision in every case, we do at least share Caleb’s concern for the future wellbeing of our compatriots and recognise that fears and anxieties can be major barriers to change. The future is in the hands of those who face up to the present realities.

Station Road Chipping Campden, Gloucestershire GL55 6LD United KingdomCampden BRI offers food analysis and testing services.

Chipping Campden, England United KingdomCampden BRI offers food analysis and testing services.

8 Finsbury Circus London, EC2M 7EA United KingdomCharles River Associates (CRA) is a leading global consulting firm that offers economic, financial, and strategic expertise to major law firms, corporations, accounting firms, and governments around the world.

B400 The Trinity Building Chesterford Business Park Little Chesterford, Saffron Walden, CB10 1XL United Kingdom

Unit 51, Greenheys Building, Manchester Science Park - Pencroft Way Manchester, Manchester, M15 6JJ United KingdomAt CDS Analytical Solutions, we deliver an unrivalled range of analytical solutions and tools for businesses in the chemical, food and pharmaceutical sectors. We specialise in chromatography method development and validation services, personalised to you and your business with a flexible approach.

6 Shenton Way OUE Downtown 2, #20-08 Singapore, 068809 United KingdomCostello Medical provides scientific support to the healthcare industry in the analysis, interpretation and communication of clinical and health economic data. Our technical expertise spans medical education, advisory boards, value materials, scientific writing, publication planning, evidence development, statistics, health economic modelling and health technology assessment; a full description of what we offer can be found on our website. Due to growing demand across an increasing range of service offerings and geographies, Costello Medical has grown organically since foundation in 2008 to a team of approximately 400 based in Cambridge, London, Manchester, Bristol, Boston and Singapore. Alongside our widening technical and creative capabilities, we remain committed to our core values of high-quality scientific work coupled with excellent customer service at competitive and transparent prices. Our talented team has experience with a variety of leading pharmaceutical companies and a track record of success in a broad range of disease areas.

1 Victoria Street Bristol, BS1 6AA United KingdomCostello Medical provides scientific support to the healthcare industry in the analysis, interpretation and communication of clinical and health economic data. Our technical expertise spans medical education, advisory boards, value materials, scientific writing, publication planning, evidence development, statistics, health economic modelling and health technology assessment; a full description of what we offer can be found on our website. Due to growing demand across an increasing range of service offerings and geographies, Costello Medical has grown organically since foundation in 2008 to a team of approximately 400 based in Cambridge, London, Manchester, Bristol, Boston and Singapore. Alongside our widening technical and creative capabilities, we remain committed to our core values of high-quality scientific work coupled with excellent customer service at competitive and transparent prices. Our talented team has experience with a variety of leading pharmaceutical companies and a track record of success in a broad range of disease areas.

1 New York Street Manchester , M1 4HD United KingdomCostello Medical provides scientific support to the healthcare industry in the analysis, interpretation and communication of clinical and health economic data. Our technical expertise spans medical education, advisory boards, value materials, scientific writing, publication planning, evidence development, statistics, health economic modelling and health technology assessment; a full description of what we offer can be found on our website. Due to growing demand across an increasing range of service offerings and geographies, Costello Medical has grown organically since foundation in 2008 to a team of approximately 400 based in Cambridge, London, Manchester, Bristol, Boston and Singapore. Alongside our widening technical and creative capabilities, we remain committed to our core values of high-quality scientific work coupled with excellent customer service at competitive and transparent prices. Our talented team has experience with a variety of leading pharmaceutical companies and a track record of success in a broad range of disease areas.

55, Old Broad Street London, EC2M 1RX United KingdomCostello Medical provides scientific support to the healthcare industry in the analysis, interpretation and communication of clinical and health economic data. Our technical expertise spans medical education, advisory boards, value materials, scientific writing, publication planning, evidence development, statistics, health economic modelling and health technology assessment; a full description of what we offer can be found on our website. Due to growing demand across an increasing range of service offerings and geographies, Costello Medical has grown organically since foundation in 2008 to a team of approximately 400 based in Cambridge, London, Manchester, Bristol, Boston and Singapore. Alongside our widening technical and creative capabilities, we remain committed to our core values of high-quality scientific work coupled with excellent customer service at competitive and transparent prices. Our talented team has experience with a variety of leading pharmaceutical companies and a track record of success in a broad range of disease areas.

50/60 Station Road Cambridge, CB1 2JH United KingdomCostello Medical provides scientific support to the healthcare industry in the analysis, interpretation and communication of clinical and health economic data. Our technical expertise spans medical education, advisory boards, value materials, scientific writing, publication planning, evidence development, statistics, health economic modelling and health technology assessment; a full description of what we offer can be found on our website. Due to growing demand across an increasing range of service offerings and geographies, Costello Medical has grown organically since foundation in 2008 to a team of approximately 400 based in Cambridge, London, Manchester, Bristol, Boston and Singapore. Alongside our widening technical and creative capabilities, we remain committed to our core values of high-quality scientific work coupled with excellent customer service at competitive and transparent prices. Our talented team has experience with a variety of leading pharmaceutical companies and a track record of success in a broad range of disease areas.

12 Bradleys Corner Hitchin, Hertfordshire, SG4 0PR United KingdomWe provide consultancy in Molecular Modelling, Computational Chemistry, Cheminformatics, Data Science and AI. With several years experience in pharmaceutical industry, both in large pharama and CROs, we are experts in applying modern computational chemistry methods for lead generation and optimization. We stay on top of the current computational chemistry techniques, incubate them and apply it for our clients.

12 Bradleys Corner Hitchin, Hertfordshire, SG4 0PR United KingdomWe provide consultancy in Molecular Modelling, Computational Chemistry, Cheminformatics, Data Science and AI. With several years experience in pharmaceutical industry, both in large pharama and CROs, we are experts in applying modern computational chemistry methods for lead generation and optimization. We stay on top of the current computational chemistry techniques, incubate them and apply it for our clients.

Birmingham Research Park Vincent Drive Edgbaston Birmingham B15 2SQ United KingdomCelentyx Ltd are a CRO specialising in bespoke assay services focused on human immunology, immuno-oncology, fibrosis and neuroinflammation. Celentyx has established local access to fresh, disease relevant patient tissue, allowing clinically us to set up customized assays with human primary cells (healthy and/or diseased). We benefit from the world-leading expertise of the neighbouring MRC Centre for Immune Regulation and Institute of Translational Medicine (Birmingham, UK). Our assays support our clients in candidate selection, medium-throughput screening, differentiation, mechanism of action, target discovery and proof of concept studies. Our technologies include multi-colour flow cytometry, multiplex cytokine analysis, multiplex quantitative immunohistochemistry, immuno-fluorescence microscopy, phenotypic screen deconvolution, quantitative image analysis, qPCR, RNAseq, and electrophysiology.

Birmingham Research Park Vincent Drive Birmingham, West Midlands, B15 1JN United KingdomCelentyx Ltd are a CRO specialising in bespoke assay services focused on human immunology, immuno-oncology, fibrosis and neuroinflammation. Celentyx has established local access to fresh, disease relevant patient tissue, allowing clinically us to set up customized assays with human primary cells (healthy and/or diseased). We benefit from the world-leading expertise of the neighbouring MRC Centre for Immune Regulation and Institute of Translational Medicine (Birmingham, UK). Our assays support our clients in candidate selection, medium-throughput screening, differentiation, mechanism of action, target discovery and proof of concept studies. Our technologies include multi-colour flow cytometry, multiplex cytokine analysis, multiplex quantitative immunohistochemistry, immuno-fluorescence microscopy, phenotypic screen deconvolution, quantitative image analysis, qPCR, RNAseq, and electrophysiology.

8 Mangers Lane Duxford, Cambs, CB22 4RN United KingdomCambridge MedChem Consulting provides a range of consultancy services in drug discovery and medicinal chemistry. https://www.cambridgemedchemconsulting.com High-Throughput Screening analysis Screening or Focused molecular Library Design Fragment-based screening support Hit to Lead project supervision Lead optimisation Computational support, in particular virtual screening and QSAR analysis. Licensing oversight Drug Discovery Resources an online resource for scientists undertaking drug discovery Training courses on the drug discovery process and medicinal chemistry.

Bassingbourn Road Bassingbourn Road Litlington, England, SG8 0SS United KingdomCresset Discovery manages and delivers outsourced computational chemistry programs for pre-clinical research. Engage our experienced scientists to work alongside your chemists to solve problems, provide fresh ideas, remove roadblocks and add direction and insight, and reach your next milestone faster and more cost effectively. Computational chemistry helps your chemists understand as much as possible about the systems they are working on. This makes it easier to direct your resources in the direction most likely to succeed, saving you time and money. Every client brings a different approach, new science and a fresh way of working. We propose methods that provide answers in the most intelligent and innovative way we can. Collaboration often sparks new and better methods and ideas, through new challenges and by the synergistic nature of contract research. We have extensive industry experience and a proven track record working on over 400 projects with many leading pharmaceutical, biotech, agrochemical, flavor and fragrance companies. As our services are flexible, you can access expertise where and when you need it you eliminate unnecessary overheads while obtaining a world class service. Use us as your long term CRO or to help navigate bottlenecks in your project.

New Cambridge House Bassingbourn Road Litlington, Cambridgeshire, SG8 0SS United KingdomCresset Discovery manages and delivers outsourced computational chemistry programs for pre-clinical research. Engage our experienced scientists to work alongside your chemists to solve problems, provide fresh ideas, remove roadblocks and add direction and insight, and reach your next milestone faster and more cost effectively. Computational chemistry helps your chemists understand as much as possible about the systems they are working on. This makes it easier to direct your resources in the direction most likely to succeed, saving you time and money. Every client brings a different approach, new science and a fresh way of working. We propose methods that provide answers in the most intelligent and innovative way we can. Collaboration often sparks new and better methods and ideas, through new challenges and by the synergistic nature of contract research. We have extensive industry experience and a proven track record working on over 400 projects with many leading pharmaceutical, biotech, agrochemical, flavor and fragrance companies. As our services are flexible, you can access expertise where and when you need it you eliminate unnecessary overheads while obtaining a world class service. Use us as your long term CRO or to help navigate bottlenecks in your project.

8/9 Spire Green Flex Meadow Harlow, Essex, CM19 5TR United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

47-48 Martingale Way BS20 7AW United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Elphinstone Research Centre Elphinstone, Scotland, EH33 2NE United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Robinson Building Little Chesterford, CB10 1XL United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

High Peak Business Park Buxton Road Chinley, SK23 6FJ United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Manston Road Margate, Kent, CT9 4LT United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

47- 48 Martingale Way Portishead, Bristol, BS20 7AW United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Elphinstone Research Center Tranent, East Lothian , EH33 2NE United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Stephenson Building Keele Science Park Keele, Keele, ST5 5SP United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Elphinstone Research Center Tranent, Edinburgh, Scotland, EH33 2NE United KingdomCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, Retrogenix, and SAMDI Tech. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com, www.retrogenix.com, and www.samditech.com.

Cowick Hall Snaith Goole East Yorkshire DN14 9AA United KingdomWe are a speciality chemical manufacturer who, through the imaginative and practical use of science, creates ingredients and technologies that improve people’s lives by enhancing everyday products.

Cowley Road, Cambridge, UKCovalAb offers antibodies, peptide design, antibody services, synthesis, and ELISAs.

Battlegate Road, Boxworth Cambridge CB23 4NN, United KingdomCambridge Environmental Assessments (CEA) are part of ADAS UK Ltd., the UK's largest environment and agricultural consultancy. CEA are specialists in regulatory environmental risk assessments for chemicals, toxicology and REACH compliance, providing strategic support for product registrations across Europe. In the pesticidal products area, CEA undertakes data evaluation, the preparation of risk assessments and regulatory documentation (dossier segments), including project management and co-ordination of work packages. In addition, CEA offer bespoke higher tier aquatic (mesocosms and laboratory studies) and higher tier environmental fate studies, according to GLP. Our chemical regulatory compliance team supports our clients to ensure they are compliant with all EU Chemical Regulations including REACH, CLP/GHS, the Seveso Directive (COMAH) and food additives. The compliance team also provides support in toxicology, ecotoxicology, exposure assessments, chemical safety reports, dossier preparation, substance identity confirmation and preparation of Safety Data Sheets. We also have extensive experience of non-standard toxicology and ecotoxicology studies, and modelling of substances in the environment.

1 The Irwin Centre Scotland Road Dry Drayton, Cambridge CB23 8AR United KingdomCambio supplies and distributes various kits, reagents, and enzymes to support research in molecular biology.

Brain and Tissue Bank The National CJD Surveillance Unit The Bryan Matthews Building Western General Hospital Crewe Road Edinburgh EH4 2XUThe purpose of this bank is to retain, store and make available for research use, post mortem tissue samples from individuals who have died with, or were suspected of having, Creutzfeldt-Jakob disease (CJD). All the samples have appropriate authorisation and ethical approval for storage in the bank and for use in research.

Cranfield Bedfordshire MK43 0AL United KingdomCranfield’s Soil Management Facility is a purpose built, state of the art resource for the advancement of soil dynamics, soil management and soil conservation techniques. The facility features environment simulation tools, which provide a world-class resource for the detailed study of soil-implement, soil-human and soil-plant-water interactions and the optimisation of machinery efficiency, performance testing and method development.

ChemOvation Ltd. Graylands Estate Langhurstwood Road Horsham West Sussex RH12 4QD United KingdomChemOvation provides organic chemistry and synthesis, computational chemistry, medicinal chemistry, screening, and purification.

Trafalgar Mills, Leeds Road, Huddersfield, West Yorkshire, HD2 1YY, UKCWF contract packaging service offers the ultimate in flexibility to operators looking for different solutions for their drinks business requirements. CWF has invested heavily in production and technology facilities over the last two decades and now have a highly efficient bottling capability. CWF has eight packaging lines including dedicated lines for wine 18.7cl / 25cl glass and PET, alcoholic ready to drinks and bag-in-box along with an automated sleeving and packing facility for mixed packs. There is high volume fermentation capacity, stainless steel temperature controlled bulk wine storage available. CWF uses traditional British winemaking practices such as Flor fermentation. Bulk wines have been bottled in 18.7cl PET format since 2001 and is one of the leading UK bottling specialists for PET. CWF was also the first packer in the UK to introduce a nitrogen flush facility to reduce oxygen contamination in bag-in-box products. CWF are the leading contract packer in the UK for customer exclusive label alcoholic ready to drinks. Glass filling options include 18.7cl, 20cl, 25cl, 27.5cl, 35cl, 50cl, 70cl, 100cl, 150cl and 200cl. Onsite bonded facilities cater for 200, 000 cases managed with a Sanderson HMC&E approved computerised system.

Cranfield Bedfordshire MK43 0AL United KingdomCranfield University is recognised internationally for its work in relation to soil and water management and the interface between agriculture and the environment. This is underpinned by our specialist expertise and a range of laboratory and field research facilities. Largest of these is the Cranfield University Experimental Farm. This is a commercially run farm which is also used for field scientific and engineering research. Located at Silsoe, Bedfordshire, the Cranfield University Experimental Farm comprises 120 hectares of arable land with a number of small farm woods and a mature agro-forestry trial site. Draining to either groundwater or local surface waters, the farm covers several different soil types, slope conditions and cropping histories that offer opportunities for replicated plot experiments, as well as field and subcatchment scale studies. Research work includes: 1. Soil and water engineering and management (soil mechanics and dynamics, on-the-go sensors to monitor soil properties, soil remediation, soil degradation, soil-plant-water interactions, nutrient management, hydraulics, tillage and cultivations) 2. Field and environmental engineering (irrigation and drainage, soil conservation, soil injection and land application of biosolids, controlled traffic farming systems, water well pumping technologies, irrigation studies and off-road vehicle capability) 3. Agricultural mechanisation (precision seeding and weeding, variable input agriculture, harvest machinery, crop processing machinery, precision drills and tillage equipment) Activities on the farm are supported by a fully dedicated Land Equipment Centre and workshops, with a range of tractor units, farm machinery and agricultural implements. The farm is used by Cranfield staff as a valuable research, training and teaching resource.

Cranfield Bedfordshire MK43 0AL United KingdomA state-of-the-art analytical facility to determine concentrations of organic compounds in vapour phase in media such as soil gas, ambient and indoor air. Technology is focused particularly on thermal desorption/gas chromatography/mass spectrometry (TD/GC/MS) with other associated systems including liquid injection GC/MS and Selected Ion Flow Tube Mass Spectrometry (SIFT-MS). Field instrumentation such as photoionisation detectors (PID) and air sampling pumps is available for site investigations. Our passive and pumped sorbent tube sampling technology enables determination of ppb concentrations of a wide range of organic chemicals in air. Sensitivity and specificity is enhanced by use of TD/GC/Time-of-Flight mass spectrometer (TOF-MS). Our experienced staff have applied technology to studies of contaminated land, occupational, ambient and indoor air quality and applied data to the assessment of risk of exposure and consequential human health effects.

Queens Road Penkhull Stoke-on-Trent, Staffordshire ST4 7LQ United KingdomCeram is a world leader in developing bioglasses and bioceramics for use as carriers for a variety of active ingredients in addition to offering chemical analysis, material analysis, and environmental analysis, and product testing services.

Stoke-on-Trent, England United KingdomCeram is a world leader in developing bioglasses and bioceramics for use as carriers for a variety of active ingredients in addition to offering chemical analysis, material analysis, and environmental analysis, and product testing services.

Hove, England United KingdomCustom Pharmaceuticals offers packing, gateway testing, regulatory services, product development, clinical trials manufacture and packing and analytical development services.

24 Cornhill London, EC3V 3ND United KingdomCrysalin develops rapid and cost effective solutions for determining protein structures where current methodologies have proved ineffective, including GPCRs and other membrane bound proteins.

Chesterford Research Park Little Chesterford Cambridge CB10 1XL UKCellCentric offers a discovery platform in epigenetics.

CABI Nosworthy Way Wallingford Oxfordshire OX10 8DE UKCABI provides microbial services and research solutions for agricultural and environmental problems.

Scottish Marine institute OBAN Argyll PA37 1QA Scotland, United KingdomCulture Collection of Algae and Protozoa (CCAP) provides a wide range of services for algal cultures in addition to maintaining the collection and supplying cultures.

Scotland United KingdomCulture Collection of Algae and Protozoa (CCAP) provides a wide range of services for algal cultures in addition to maintaining the collection and supplying cultures.

200 Western Avenue Cardiff, Wales, CF5 2YB United Kingdom

Pendragon House Caxton Place Cardiff Cardiff CF23 8XE United KingdomCutest Systems excel in performing safety, efficacy and claim substantiation/proof-of-concept testing for cosmetics, toiletries, pharmaceuticals, medical devices and nutritional supplements.

Rivers Lodge West Common Harpenden, Hertforshire, AL5 2JD United KingdomCovalence Research Ltd is a small-scale agency focussed on delivering high-quality health economic models and analyses, systematic literature reviews, and medical writing services.

51 Hayes Grove London, SE22 8DF United KingdomCovalence Research Ltd is a small-scale agency focussed on delivering high-quality health economic models and analyses, systematic literature reviews, and medical writing services.

6 Tom McDonald Avenue, Dundee, DD2 1NH, UK Cypex manufactures quality DMPK enzymes (e.g. P450s, SULTs, AOX) from a number of species and offers related chemicals and antibodies. Services: bespoke protein expression, inhibition screening. Cypex provides metabolite synthesis, protein expression, CYP inhibition screening, recombinant cytochrome P450s (bactosomes), and research products.

6 Tom McDonald Avenue Dundee, Scotland, DD2 1NH United Kingdom Cypex manufactures quality DMPK enzymes (e.g. P450s, SULTs, AOX) from a number of species and offers related chemicals and antibodies. Services: bespoke protein expression, inhibition screening. Cypex provides metabolite synthesis, protein expression, CYP inhibition screening, recombinant cytochrome P450s (bactosomes), and research products.

Maia Building Babraham Research Pack Cambridge, CB22 3AT United KingdomCell Guidance Systems provides reagents and services to control, manipulate and monitor the cell, both in-vitro and in-vivo. Our technologies enable novel insights for research as well as fresh approaches to treating disease. We have developed a range of products and services to support your exosome research, from isolation to characterization to assay. Our range of products includes exosome purification kits for all biological fluids and applications, exosome marker antibodies, and exosome detection options, as well as a nanoparticle tracking analysis (NTA) service. Conventional growth factors limit the possibilities of cell culture, biomanufacturing, and therapeutics. PODS® technology addresses the limitations of conventional growth factors by placing them in a protective protein crystal lattice. This lattice stabilizes cargo proteins even at high temperatures. In the presence of proteases secreted by cells, pores develop in the lattice which allows the cargo growth factor to slowly escape. This gradual, sustained release maintains bioavailability at steady-state levels (near zero-order kinetics). The crystals can also be readily used for patterning by attachment to surfaces or suspension at specific positions in hydrogels. PODS® nanocrystals have a wide range of applications either in-vitro (2D or 3D culture) or in-vivo.

Cell Guidance Systems Ltd, Babraham Bioscience Campus, Cambridge CB22 3AT United KingdomCell Guidance Systems provides reagents and services to control, manipulate and monitor the cell, both in-vitro and in-vivo. Our technologies enable novel insights for research as well as fresh approaches to treating disease. We have developed a range of products and services to support your exosome research, from isolation to characterization to assay. Our range of products includes exosome purification kits for all biological fluids and applications, exosome marker antibodies, and exosome detection options, as well as a nanoparticle tracking analysis (NTA) service. Conventional growth factors limit the possibilities of cell culture, biomanufacturing, and therapeutics. PODS® technology addresses the limitations of conventional growth factors by placing them in a protective protein crystal lattice. This lattice stabilizes cargo proteins even at high temperatures. In the presence of proteases secreted by cells, pores develop in the lattice which allows the cargo growth factor to slowly escape. This gradual, sustained release maintains bioavailability at steady-state levels (near zero-order kinetics). The crystals can also be readily used for patterning by attachment to surfaces or suspension at specific positions in hydrogels. PODS® nanocrystals have a wide range of applications either in-vitro (2D or 3D culture) or in-vivo.

Moneta Building Babraham Bioscience Campus Cambridge, CB22 3AT United KingdomCell Guidance Systems provides reagents and services to control, manipulate and monitor the cell, both in-vitro and in-vivo. Our technologies enable novel insights for research as well as fresh approaches to treating disease. We have developed a range of products and services to support your exosome research, from isolation to characterization to assay. Our range of products includes exosome purification kits for all biological fluids and applications, exosome marker antibodies, and exosome detection options, as well as a nanoparticle tracking analysis (NTA) service. Conventional growth factors limit the possibilities of cell culture, biomanufacturing, and therapeutics. PODS® technology addresses the limitations of conventional growth factors by placing them in a protective protein crystal lattice. This lattice stabilizes cargo proteins even at high temperatures. In the presence of proteases secreted by cells, pores develop in the lattice which allows the cargo growth factor to slowly escape. This gradual, sustained release maintains bioavailability at steady-state levels (near zero-order kinetics). The crystals can also be readily used for patterning by attachment to surfaces or suspension at specific positions in hydrogels. PODS® nanocrystals have a wide range of applications either in-vitro (2D or 3D culture) or in-vivo.

Building 42 Charnwood Campus 9 Summerpool Road LOUGHBOROUGH, LE11 5RD United KingdomCharnwood Molecular is a pre-clinical CRO which specialises in enhancing the experience and success of complex drug discovery for clients globally. We offer a flexible service from the synthesis or testing of single compounds to the full management of integrated projects. In addition we can offer computational chemistry, assay development, biology screening, target identification, DMPK and much more.

Charnwood Molecular Limited, The Heritage Building 7 Beaumont Court, Prince William Road Loughborough, Leicestershire, LE11 5DA United KingdomCharnwood Molecular is a pre-clinical CRO which specialises in enhancing the experience and success of complex drug discovery for clients globally. We offer a flexible service from the synthesis or testing of single compounds to the full management of integrated projects. In addition we can offer computational chemistry, assay development, biology screening, target identification, DMPK and much more.

Unit 69, Listerhills Science Park, Campus Road Bradford, West Yorkshire, BD7 1HR United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

NINE, Edinburgh BioQuarter 9 Little France Road Edinburgh, EH16 4UX United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

20 Campus Road England, BD7 1HR United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

Alderley Road Alderley Edge Alderley Edge, England, SK10 4TG United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

Frith Knoll Road High Peak England, SK23 0PG United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

Frith Knoll Road Chapel-en-le-Frith High Peak, Derbyshire, SK23 0PG United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

2 James Lindsay Place Dundee Technopole Dundee, DD1 5JJ United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

Discovery House Discovery Park, Ramsgate Road Sandwich , CT13 9ND United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

NINE, Edinburgh BioQuarter 9 Little France Road Edinburgh , EH16 4UX United KingdomConcept Life Sciences is a knowledge-based, science-led business providing a wide range of innovative and integrated solutions to clients in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. We also work closely with academic groups. Formed in 2014, our business has expanded through a mix of organic growth and targeted acquisition. Today, we are home to more than 400 employees, working from 7 sites across the UK, sharing a common focus on problem solving, quality, collaboration, communication and flexibility. By bringing together teams of highly trained scientists, excellent laboratory facilities and an in-depth understanding of our core markets, we have created a business that is greater than the sum of its parts. This synergy means we have the in-house resources to offer a range of integrated services to our clients. Our operations are structured around two divisions. Our Integrated Discovery and Development Services division supports discovery and development in the pharmaceutical, biotechnology, agrochemical, chemical and consumer industries. Our Analytical Services division provides an extensive range of integrated services to clients in the life sciences, industrial and environmental sectors. Following our acquisition of Aquila BioMedical in 2017 we are pleased to now support specialist research in immunology, immuno-oncology, neurodegeneration, fibrosis, regenerative medicine, histology and GCP analysis

Hillcrest Dodgeford Lane, Belton Loughborough, Leicestershire, LE12 9TE United KingdomCrown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) providing discovery, preclinical and translational platforms to advance oncology, immuno-oncology, and immune-mediated inflammatory diseases. Known for their high quality and expansive in vivo, in vitro and ex vivo preclinical models, they partner with their clients to quantify the efficacy and pharmacological profile of their drug candidate before they move into the clinic. The company is the only preclinical CRO to provide tumor organoid services utilizing HUB technology and has the world’s largest commercially available PDX collection. Additionally, further services available in the areas of high content imaging and a 3D Ex Vivo Patient Tissue Platform, provide greater insights into complex disease pathophysiology. A range of biomarker analysis and applied genomics services are also available to optimize therapeutic benefit. Crown Bioscience helps to deliver superior drug candidates to ensure that patients get the right treatment at the right time. Founded in 2006, Crown Bioscience has 14 facilities in the US, Europe, and APAC. Find out more: www.crownbio.com

Hillcrest, Dodgeford Lane Belton, Loughborough Leicestershire , LE12 9TE United KingdomCrown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) providing discovery, preclinical and translational platforms to advance oncology, immuno-oncology, and immune-mediated inflammatory diseases. Known for their high quality and expansive in vivo, in vitro and ex vivo preclinical models, they partner with their clients to quantify the efficacy and pharmacological profile of their drug candidate before they move into the clinic. The company is the only preclinical CRO to provide tumor organoid services utilizing HUB technology and has the world’s largest commercially available PDX collection. Additionally, further services available in the areas of high content imaging and a 3D Ex Vivo Patient Tissue Platform, provide greater insights into complex disease pathophysiology. A range of biomarker analysis and applied genomics services are also available to optimize therapeutic benefit. Crown Bioscience helps to deliver superior drug candidates to ensure that patients get the right treatment at the right time. Founded in 2006, Crown Bioscience has 14 facilities in the US, Europe, and APAC. Find out more: www.crownbio.com

Roslin Innovation Centre, Easter Bush campus Edinburgh, Midlothian, EH25 9RG United KingdomCarcinotech is a MedTech company with expertise in manufacturing 3D printed tumours using patient-derived biopsies, cancer stem cells, immune cells. Carcinotech’s advanced models provide a platform for rapid, ethical, sustainable, and accurate drug discovery, screening, and pre-clinical testing. Working with global partners, leading pharma companies, surgeons, pathologists, clinicians, and industry-leaders, the goal is to accelerate drug discovery and enable delivery of more effective cancer treatments to market. Access to Carcinotech’s robotic and automated manufacturing allows for accelerated production, with models offering high-throughput capabilities.

Roslin Innovation Centre, Easter Bush campus Edinburgh, Midlothian, EH25 9RG United KingdomCarcinotech is a MedTech company with expertise in manufacturing 3D printed tumours using patient-derived biopsies, cancer stem cells, immune cells. Carcinotech’s advanced models provide a platform for rapid, ethical, sustainable, and accurate drug discovery, screening, and pre-clinical testing. Working with global partners, leading pharma companies, surgeons, pathologists, clinicians, and industry-leaders, the goal is to accelerate drug discovery and enable delivery of more effective cancer treatments to market. Access to Carcinotech’s robotic and automated manufacturing allows for accelerated production, with models offering high-throughput capabilities.

11 Whittle Parkway, Progress Business Park Slough, SL1 6DQ United KingdomCliniSciences is a French company headquartered in Paris. CliniSciences is a distributor products & services from suppliers based all around the world. CliniSciences owns 10 other companies (Anawa, Biotrend, Generon, Hexabiogen, Kyvobio, Quimigen) based throughout Europe including the United Kingdom, Germany, Spain, Italy, The Netherlands & Switzerland. Through these companies we offer life science reagents, services and instruments. We sell products & services for research and diagnostic use. Products include reagents, cells, human samples and more. Services include antibody development, peptide synthesis, bulk manufacture, humanization and more.

200 Western Avenue Cardiff, Wales, CF5 2YB United Kingdom

Department of Surgery and Cancer Imperial College London Room 11L05 Charing Cross Hospital Fulham Palace Road London W6 8RFThe CTB (Chernobyl Tissue Bank) is a unique venture. It is the first international cooperation that seeks to establish a collection of biological samples from tumours and normal tissues from patients for whom the aetiology of their disease is known - exposure to radioiodine in childhood. The project, which started in October 1998, has been supported by a number of sponsors including the European Commission, the WHO, the National Cancer Institute (NCI) of the USA and the Sasakawa Memorial Health Foundation of Japan (SMHF). The project is currently jointly funded by the NCI and the SMHF. The project is coordinated from Imperial College, London and works with Institutes in the Russian Federation (the Medical Radiological Research Centre in Obninsk) and Ukraine (the Institute of Endocrinology and Metabolism in Kiev) to support local scientists and clinicians to manage and run a tissue bank for those patients who have developed thyroid tumours following exposure to radiation from the Chernobyl accident. Belarus was also initially included in the project, but is currently suspended for political reasons.

4 Technopark, Newmarket Road Cambridge, CB5 8PB United KingdomCytocell offers FISH probes and DNA screening solutions.

9 High Street Stevenage Old Town, SG1 3BG United KingdomCK Clinical offers clinical and pharmaceutical recruitment services.

133 Finnieston Street Glasgow, G3 8HB United KingdomClinTec International is an innovative medium-sized Contract Research Organization providing full service support to the pharmaceutical, biotechnology and medical device industry. ClinTec has a global reach in over 50 countries worldwide. This also includes a strong presence in the emerging markets of Asia, the Middle East and the North African region. ClinTec has a wealth of expertise in managing clinical trials in all major therapeutic categories including oncology, rare diseases, neurology, autoimmune diseases and diabetes.

Cranfield Bedfordshire MK43 0AL United KingdomThe laboratory is for measuring whole-soil carbon balances and greenhouse gas fluxes, including stable-isotope compositions, in large, intact, hydrologically-isolated soil monoliths (lysimeters) under field conditions. It contains 24 lysimeters connected to automated gas flux chambers and instruments. The lysimeters are 0.8m in diameter and 1m deep, i.e., at least the size of a soil pedon, and therefore representative of field soil conditions. Each is equipped with systems for controlling soil moisture and surface temperature, and instruments to allow near continuous sampling of gases emitted from the surface, dissolved solutes passing out of the bottom, and temperature, moisture and soil solution at different depths. Onsite environmental conditions are monitored with a weather station. The gas flux chambers (26cm head space) are fixed over the soil surface and have pneumatically operated lids. Gases accumulated in the head space when the lids are closed are passed through a continuous loop to an infra red gas analyser (IRGA) and an isotope ratio mass spectrometer (IRMS) housed in an instrument building. This allows simultaneous analysis of CO2 , CH4 , N2O, O2 and N2 and their C, O and N isotope compositions at natural or enriched abundances. The soil monoliths in the lysimeters contain electrical heating elements in the surface, capable of maintaining the soil surface at up to 5 o C above ambient temperature. They also have automated sprinkler irrigation systems, delivering rainwater collected from the roof of the instrument building. Presently the system contains two soil types planted with grass. These are a well-drained, acid, coarse loamy soil from Bedfordshire, and a poorly-drained, seasonally waterlogged loamy soil over clay from Warwickshire. The soil monoliths were taken intact from these sites, preserving the natural soil structure, and brought to Cranfield.

Depot Road, Newmarket, CB8 0ALChemtest is a leading supplier of high quality, fast response analytical services. "Customer focus and continuous investment in our personnel, processes and technology are at the forefront of our business planning, enabling reliability and confidence in the results we provide." Analysis is undertaken for the following industry sectors: Environmental Industry Geotechnical Industry Rail Industry Airports Local Government Construction Industry Asbestos Management Chemtest offers both fast and standard turnarounds to meet with clients' requirements and deadlines. The provision of sample containers and custody documentation, sample collection and reporting costs are included in the price of analysis. Sample collection is mostly provided utilising in-house drivers to ensure timely and safe sample delivery to the laboratory so that samples are received in optimum condition for analysis with traceability from the sample origin. Couriers are sometimes used when this is not practical. Chemtest can provide bespoke reporting formats in several different media according to clients' specifications.

Cambrigbe, UKThe Cambridge Brain Bank was established in 1975 to allow researchers access to brain tissue to investigate disorders of the nervous system, and offers a well-characterised resource of frozen and paraffin embedded brain tissue from donors with Dementia, including Alzheimer’s disease, Motor Neurone disease and Huntington’s disease, as well as a comprehensive histological service. Normal control brain tissue from people without neurological disorders is also available. The CBB is licensed by the Human Tissue Authority (HTA) and accredited by Clinical Pathology Accreditation (CPA). The facility routinely supplies material to researchers working in Neuroscience, as well as University and Medical Research Council (MRC) funded research projects. The brain bank is also a member of the MRC Brain UK network.

155 Cambridge Science Park , Milton Road Cambridge, CB4 0GN United KingdomCantab Biopharmaceuticals is focused on the development of "biosuperior" products with extensive experience in biopharmaceutical discovery, process development and GMP manufacturing.

Cambridge, England United KingdomCantab Biopharmaceuticals is focused on the development of "biosuperior" products with extensive experience in biopharmaceutical discovery, process development and GMP manufacturing.

Mochdre, SY16 4LE, UKCellPath provides manufacture and supply of histology and cytology products.

Scott House Alencon Link Basingstoke, RG21 7PP United KingdomClinical Solutions International provides market research, clinical consulting, medical device experience, and study design.

Cranfield Bedfordshire MK43 0AL United KingdomWater is the most important factor limiting crop production on a global scale; water resources are increasingly under pressure due to population growth, climate change, competition from diverse users and the desire to prevent environment damage. The Crop Water Use Group takes a multidisciplinary approach to improve crop production when water is limiting. Our research projects include the disciplines of plant physiology, molecular biology, molecular genetics, soil water dynamics and irrigation science.

Meditrina Building 260 Babraham Research Campus Cambridge CB22 3ATCrescendo Biologics focuses on in vivo generation of human heavy chain antibodies through transgenic mice, developing therapeutic antibodies, and affinity optimization using ribosome display platforms.

200 Western Avenue Cardiff, Wales, CF5 2YB United Kingdom

Cambridge, UKCompChem Solution provides computational chemistry support, library design and chemoinformatics services.

Cambridge, England United KingdomCompChem Solution provides computational chemistry support, library design and chemoinformatics services.

England United KingdomCefas Technology Limited (CTL) is a wholly owned subsidiary of Cefas that specialises in the application of Cefas technology to specific customer needs in a cost effective and focussed manner. CTL products, services and systems are developed by teams that are experienced in fisheries and environmental management and of working closely with clients to ensure that their needs are fully met. Our technical solutions are offered alongside the wide range of research and consultancy processes and services that Cefas offers. Cefas is a multidisciplinary scientific research and consultancy centre providing a comprehensive range of services in fisheries management, environmental monitoring and assessment and aquaculture to a large number of worldwide clients. Cefas has 550 staff and has a long and successful track record in delivering high quality services to clients in a confidential and impartial manner. Cefas has wide experience in delivering reliable, cost effective Information Systems that integrate processes and information across different organisations and locations using the latest Internet based technology to reduce costs and to improve access to data. Cefas’s team of 25 application developers is complemented by specialists with in depth experience of the use of environmental and fisheries information, communications and data management, laboratory management systems, use of GIS systems, process modelling and statistics and coastal zone management.

Unit J, Broad Lane Industrial Estate Cottenham, Cambridge CB24 8SW, UKChemex are a long established GLP Compliant laboratory based in the UK, performing a range of aquatic and terrestrial ecotoxicology studies for an international client base. In addition, our Consultancy Group are on hand to assist with projects including laboratory auditing and training and have experience working in many countries around the globe. Over 25 years since its founding, Chemex remains dedicated to the same quality philosophies, which have driven the company’s success. The company has assembled a technically diverse staff, enabling us to develop and expand our Ecotoxicology services delivering timely reports to an ever-expanding international client base. Chemex performs a range of aquatic toxicology studies to both Marine & Freshwater species and also offer terrestrial toxicology studies. In addition, biodegradation and bioaccumulation studies and many other study types are available to fulfil international regulatory requirements. To compliment our toxicology studies Chemex has a comprehensive range of analytical instrumentation and expert analysts to enable confirmation of test substance concentrations throughout studies, where specified. Our GLP compliant facility near Cambridge, UK provides independent laboratory testing of the highest quality and excellent customer service to a diverse range of clients. Chemex are one of the few UK laboratories that offer a wide range of marine studies suitable for OCNS (Offshore Chemicals Notification System)/HOCNF (Harmonised Offshore Chemicals Notification Format) purposes. More cost effective screening methods are also available for initial determination of the most suitable chemicals/products to proceed with. In addition, Chemex' multilingual Consultancy Group are able to assist with projects such as, Laboratory Auditing, Staff Training in various aspects of sampling or analysis techniques, off-shore sampling, production of Quality Plans and data review services. Our team are on hand to assist with projects around the globe. Chemex professional staff comprises skilled and experienced scientists, chemists, biologists and technicians with many years’ experience in ecotoxicology and analytical chemistry. We place a great deal of emphasis on training in order to maintain the highest levels of expertise, efficiency and GLP compliance.

38 Kingsley Crescent High Wycombe, Buckinghamshire, HP11 2UL United KingdomConnectHEOR is a healthcare consulting company specialised in providing high-quality Health Economics & Outcomes Research (HEOR) services and training. We are able to support requests from the world's top pharma and biotechs using scientist.com "SEND US A REQUEST FOR PROPOSAL TODAY" At ConnectHEOR, we advance healthcare with the power of data and research by hiring HEOR experts with technical rigour to provide creative solutions to complex HEOR problems. Our key services include: 1. Decision Modelling 2. Real-World Evidence and Data Analytics 3. Review and Evidence Synthesis 4. Market Access and Value Communication 5. Training Why us? : 1. Academic rigour with commercial awareness 2. Senior team works on the project materially - unlike other vendors 3. Small and focused team, supports clients hands-on from start to end (and beyond) of the projects 4. High quality deliverables, cost-effective pricing

Upper Heyford, England, OX25 United KingdomCytome Technologies is a contract research organisation specialising in characterisation of the immunoproteome using bioanalytical, biophysical and cell biology assays. We provide assay and custom assay development services to pharmaceutical and biotechnology clients.

14 Cundel Dr. Cambridge CB24 8RU UKChemPharmaServe provides innovative solutions to pharmaceuticals and biotechs to help fast tracking their drug discovery and developmental projects by making novel molecules they need.

14 Cundell Drive, Cottenham Cambridge CB4 8RU UKChemPharmaServe provides innovative solutions to pharmaceuticals and biotechs to help fast tracking their drug discovery and developmental projects by making novel molecules they need.

Cambridge, England United KingdomChemPharmaServe provides innovative solutions to pharmaceuticals and biotechs to help fast tracking their drug discovery and developmental projects by making novel molecules they need.

Easter Bush Campus Scotland, EH25 9RG United KingdomCenso Bio is a specialist CNS discovery services company using human iPSC to support neurodegenerative and neuro-inflammation focused discovery projects. Censo provides access to a diverse range of existing human iPSC lines, and ethically sources relevant human tissue, both healthy and with disease specific mutations, with which to custom generate new iPSC lines from large cohorts of individuals. We can gene edit these lines to knock in, knock out or correct target genes of interest, and have developed reproducible differentiation protocols for a number of lineages, including microglia, astrocytes, cortical, and sensory neurons. Using these cells for neurodegenerative and neuro-inflammatory disease discovery, we offer customisable phenotypic assays to deliver new insights and functional disease related understanding of our clients compounds, Our technology also enables the study of genotype-phenotype relationships in large populations, providing an understanding of patient population therapeutic response variability.

B260 Meditrina Babraham, England, CB22 3AT United KingdomCenso Bio is a specialist CNS discovery services company using human iPSC to support neurodegenerative and neuro-inflammation focused discovery projects. Censo provides access to a diverse range of existing human iPSC lines, and ethically sources relevant human tissue, both healthy and with disease specific mutations, with which to custom generate new iPSC lines from large cohorts of individuals. We can gene edit these lines to knock in, knock out or correct target genes of interest, and have developed reproducible differentiation protocols for a number of lineages, including microglia, astrocytes, cortical, and sensory neurons. Using these cells for neurodegenerative and neuro-inflammatory disease discovery, we offer customisable phenotypic assays to deliver new insights and functional disease related understanding of our clients compounds, Our technology also enables the study of genotype-phenotype relationships in large populations, providing an understanding of patient population therapeutic response variability.

51 Hayes Grove London, SE22 8DF United KingdomCovalX offers mass spectrometry service for protein characterization with special focus on conformational epitope mapping (HDX-MS, XL-MS). Other services includes sequence verification, intact mass, protein interaction test, aggregation. all mass spectrometry analysis for therapeutic proteins.

Crystec Ltd, Norcroft Building Richmond Road Bradford, West Yorkshire, BD7 1DP United KingdomCrystec applies the latest supercritical fluid (SCF) technology to improve the design and performance of medicines. We provide crystal and particle engineering solutions to the pharmaceutical and biopharmaceutical industries, contributing to human health by enabling new and more effective therapies. Crystec SCF technology can be applied to small and large drug molecules in a range of dosage forms. Our services include crystal form screening and particle design (including composite particles and co-crystals), addressing issues of poor solubility and stability, improved delivery, and product enhancement in support of lifecycle management. Our process is scaled to GMP manufacturing levels. We are also engaged in in-house programmes to develop improved products and currently have licensing opportunities available in several therapeutic areas, including urge incontinence, fungal infections, and malaria. The first product based on SCF technology is expected to launch this year. It is an inhaled product for migraine - SCF processing enables exceptional particle size control and lung deposition resulting in rapid uptake. The particle design and scale-up to GMP for this product were managed by members of the Crystec team.

9 Tumbling Hill Street Richmond Road England, BD7 1DB United KingdomCrystec applies the latest supercritical fluid (SCF) technology to improve the design and performance of medicines. We provide crystal and particle engineering solutions to the pharmaceutical and biopharmaceutical industries, contributing to human health by enabling new and more effective therapies. Crystec SCF technology can be applied to small and large drug molecules in a range of dosage forms. Our services include crystal form screening and particle design (including composite particles and co-crystals), addressing issues of poor solubility and stability, improved delivery, and product enhancement in support of lifecycle management. Our process is scaled to GMP manufacturing levels. We are also engaged in in-house programmes to develop improved products and currently have licensing opportunities available in several therapeutic areas, including urge incontinence, fungal infections, and malaria. The first product based on SCF technology is expected to launch this year. It is an inhaled product for migraine - SCF processing enables exceptional particle size control and lung deposition resulting in rapid uptake. The particle design and scale-up to GMP for this product were managed by members of the Crystec team.

18 Sedley Taylor Road Cambridge, England, CB2 8PW United KingdomThe Centre for Business Innovation Limited (CfBI) headquartered in Cambridge, UK, creates and facilitates communities whose participants share the benefits and costs of working together in a trusting environment, towards common goals or under a brand which reflects their values and beliefs in the spirit of Open Innovation

12 Union Road Cambridge, Cambridgeshire, CB2 1EZ United KingdomScientific consultancy from CCDC allows you to gain access to our talented and enthusiastic structural science researchers, developers and technical specialists; and a wealth of knowledge and expertise. Our services include contract research, solid-form services, discovery services and data curation. Your time and resource to spend on research projects is limited, and you want to be sure you are utilizing all tools to best advantage. Why not let our contract research team take on some of the load? Harness our extensive expertise in structural chemistry including structure based virtual screening, series optimization, 3D model validation and much more. Get extra assurances about your solid form product, backed by the world’s structural chemistry knowledge. Our secure, cheminformatics-based analyses can help to identify potential polymorphs, solvates, hydrates, stability issues, and more. The CCDC has a long history of partnerships with top pharmaceutical companies. We deeply understand solid form informatics, data security, and the need for reliable, timely results. We analyze your crystal structure data using software and scripts powered by the Cambridge Structural Database, or CSD, the world’s repository of experimentally determined small molecule organic and metal-organic crystal structures. With this collective knowledge, harnessed from the scientific literature and direct data sharing since 1965, your structure’s properties are assessed. This does not replace experimental solid form screening but helps to inform, prioritize and validate this work. Our trusted Solid Form Healthcheck approach has seen success in the literature, with Pfizer using this method to identify risks in a viral entry inhibitor that had been missed in the experimental screen (Docherty et al. Journal of Pharmacy and Pharmacology, 2015, 67, 6, 857-868).

Bo'Ness Road ML1 5UH United Kingdom Clyde Biosciences is a specialized CRO focused on measuring and interpreting drug effects on cardiac cell function. Our unique approach allows in a single assay to screen for a broad spectrum of cardiovascular liabilities that include single and multiple ion channel effects, inotropic actions, time dependent effects, complex pharmacology, chronic effects and cardiotoxicity. This allows for early screening of candidate compounds as well as supporting late stage compounds with known cardiac liabilities needing risk assessment. We support drug development across a broad array of areas including heart failure, vascular biology, neural, oncology, diabetes and metabolism, immunology and infectious diseases.

BioPark Hertfordshire Broadwater Road Welwyn Garden City Hertfordshire AL7 3AX, UKCN Bio is a leading organ-on-a-chip (OOC) company that offers a portfolio of products and services to optimise the accuracy and efficiency of bringing new medicines to market; providing significant savings in cost and time to drug discovery and development pipelines. Our range of lab-benchtop PhysioMimix™ microphysiological systems (MPS) enables researchers to model human biology in the lab through rapid and predictive 3D human tissue-based studies that harness microfluidic technology to provide nutrients and mimic blood flow. The technology bridges the gap between traditional cell culture and human studies, advancing towards the simulation of human biological conditions to support the accelerated and more efficient development of new therapeutics, whilst reducing the dependence on animal model usage. CN Bio’s MPS support researchers that require reliable, data-rich, in vitro studies, to uncover the mechanisms of disease (e.g non-alcoholic steatohepatitis (NASH), Hepatitis B virus, or COVID-19 infection), identify novel therapeutic targets, or investigate drug efficacy, pharmacokinetics and potential toxicity. Next-generation PhysioMimix OOC models span a range of organ types, including lung, liver and gut. Single organs can be linked together into multi-organ systems to simulate processes such as drug absorption and metabolism, or to understand interactions between organs, such as inflammation. Harnessing these assays, our portfolio of MPS, NASH-in-a-box kit, 3D validated cells, compatible consumable plates and contract research services have been developed to address drug development bottlenecks across a range of therapeutic areas, including metabolic and infectious diseases, oncology, and inflammation.

CN Bio Innovations 332 Cambridge Science Park, Cambridge, Cambridgeshire, CB4 0WN United KingdomCN Bio is a leading organ-on-a-chip (OOC) company that offers a portfolio of products and services to optimise the accuracy and efficiency of bringing new medicines to market; providing significant savings in cost and time to drug discovery and development pipelines. Our range of lab-benchtop PhysioMimix™ microphysiological systems (MPS) enables researchers to model human biology in the lab through rapid and predictive 3D human tissue-based studies that harness microfluidic technology to provide nutrients and mimic blood flow. The technology bridges the gap between traditional cell culture and human studies, advancing towards the simulation of human biological conditions to support the accelerated and more efficient development of new therapeutics, whilst reducing the dependence on animal model usage. CN Bio’s MPS support researchers that require reliable, data-rich, in vitro studies, to uncover the mechanisms of disease (e.g non-alcoholic steatohepatitis (NASH), Hepatitis B virus, or COVID-19 infection), identify novel therapeutic targets, or investigate drug efficacy, pharmacokinetics and potential toxicity. Next-generation PhysioMimix OOC models span a range of organ types, including lung, liver and gut. Single organs can be linked together into multi-organ systems to simulate processes such as drug absorption and metabolism, or to understand interactions between organs, such as inflammation. Harnessing these assays, our portfolio of MPS, NASH-in-a-box kit, 3D validated cells, compatible consumable plates and contract research services have been developed to address drug development bottlenecks across a range of therapeutic areas, including metabolic and infectious diseases, oncology, and inflammation.

No.24 Mereside Alderley Park Macclesfield, Cheshire, SK10 4TG United KingdomCyprotex, an Evotec company, has sites at Alderley Park near Macclesfield, UK and in Watertown near Boston, USA. The company has dedicated and highly qualified employees with proven experience in a wide range of specialist techniques acquired across diverse industries. The majority of our clients focus in pharmaceutical research, however, we also support clients in the chemical, cosmetics and personal care, agrichemical and tobacco industries. Cyprotex specialises in in vitro and in silico ADME-Tox services. This includes in vitro ADME screening to support discovery projects, regulatory in vitro ADME and DDI studies during preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models (e.g. 3D models and MEA electrophysiology) and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on R&D and our scientists regularly present our findings at scientific conferences and through publications. In August 2017, Evotec acquired Aptuit in order to further expand the Group’s capabilities. As well as additional complementary drug discovery capabilities, Aptuit offers full CMC and IND-enabling services allowing the Evotec Group to provide expert support across the value chain from early discovery through to preclinical development and beyond

Cambridge, UKCambridge Bioscience is a UK-based distributor of life science research and diagnostic products. Throughout our history we have collaborated with many companies who have developed the research tools which have shaped the modern world of biological research. Today, we offer a unique range of products and services that we have carefully selected for their ability to contribute to future discoveries. We mostly offer three key types of products and services : Human biospecimens - We have decades of experience in sourcing human biospecimens that have been collected, processed and transported in a manner that makes them suitable for the most demanding research applications. Reagents - we source 1000's of reliable and innovative biological and chemical reagents. Instruments - We focus on innovative, instrument-based products for cell and molecular biology research that help researchers gain greater understanding of complex biological systems.

Munro House Trafalgar Way Cambridge , CB23 8SQ United KingdomCambridge Bioscience is a UK-based distributor of life science research and diagnostic products. Throughout our history we have collaborated with many companies who have developed the research tools which have shaped the modern world of biological research. Today, we offer a unique range of products and services that we have carefully selected for their ability to contribute to future discoveries. We mostly offer three key types of products and services : Human biospecimens - We have decades of experience in sourcing human biospecimens that have been collected, processed and transported in a manner that makes them suitable for the most demanding research applications. Reagents - we source 1000's of reliable and innovative biological and chemical reagents. Instruments - We focus on innovative, instrument-based products for cell and molecular biology research that help researchers gain greater understanding of complex biological systems.

Trafalgar Way Bar Hill, England, CB23 8SQ United KingdomCambridge Bioscience is a UK-based distributor of life science research and diagnostic products. Throughout our history we have collaborated with many companies who have developed the research tools which have shaped the modern world of biological research. Today, we offer a unique range of products and services that we have carefully selected for their ability to contribute to future discoveries. We mostly offer three key types of products and services : Human biospecimens - We have decades of experience in sourcing human biospecimens that have been collected, processed and transported in a manner that makes them suitable for the most demanding research applications. Reagents - we source 1000's of reliable and innovative biological and chemical reagents. Instruments - We focus on innovative, instrument-based products for cell and molecular biology research that help researchers gain greater understanding of complex biological systems.

Whiteleaf Business Centre 11 Little Balmer Buckingham Bucks UK MK18 1TFProvide services for Life Science/Drug Discovery scientists. Includes sourcing cells & tissue, customer antibodies & tetramers, custom angiogenesis experiments, numerous immunological assays. Over 200,000 reagents.

Caltag Medsystems United Kingdom Buckingham, Bucks, MK18 1TF United KingdomProvide services for Life Science/Drug Discovery scientists. Includes sourcing cells & tissue, customer antibodies & tetramers, custom angiogenesis experiments, numerous immunological assays. Over 200,000 reagents.

Burnham, England United KingdomCMOpharma offers CMC consultancy services with expertise in outsourcing chemical development, solid-state physicochemical studies and API manufacture.

Unit 1 Speedwell Works 73 Sidney Street Sheffield, South Yorkshire, S1 4RG United Kingdom The EI-FLEX is a single-molecule fluorescence spectrometer for single molecule FRET (smFRET), fluorescence correlation spectroscopy (FCS) and fluorescence cross-correlation spectroscopy (FCCS). We have simplified single molecule processes to deliver easy-to-use bench-top equipment that will complement and enhance your existing techniques. Key applications include: Protein and nucleic acid interaction analysis; Fast conformational dynamics; Biophysics and life-science discoveries; Drug development and diagnostics. smFRET and FCS are increasingly important tools to address fundamental questions about biological processes, including protein conformation dynamics, ion channel dynamics, DNA repair and maintenance, interactions between receptors and ligands, and membrane transport. These processes make up several aspects that are crucial to understand when investigating solutions within health research. Single molecule results remove ensemble averages, giving a true view of how your molecule is acting under specific conditions. The EI-FLEX detects molecules in confocal solution, meaning the molecule can act as it does in nature without being adhered to a surface and negates the need for multi-step slide preparation. Exciting Instruments Ltd is a joint venture, built in Sheffield, stemming from the software brains of Bulldozer Ltd and the single-molecule expertise of Dr Timothy Craggs. As a true partnership of science and software, we also provide accessible software that can visualise your results in real time, analyse data and produce publication standard figures, and save all data and user details to the cloud.

94 Rickmansworth Road Watford Herts WD18 7JJ United KingdomFleet Laboratories provides manufacturing of toiletry and pharmaceuticals.

78 Lancaster Way Business Park, Ely, Cambridgeshire, CB6 3NW, United KingdomCambridge Commodities Limited (CCL) is located in Cambridgeshire, England. We are the leading importer, distributor and manufacturer of nutritional ingredients, as well as made-to-specification finished products.

Unit 2 Winchester Hill Romsey Hampshire SO51 7UT UKCapsant Neurotechnologies provides in-vitro tissue based screening technologies based on ex-vivo tissues and reaggregated 3D systems.

Romsey, England, SO51 United KingdomCapsant Neurotechnologies provides in-vitro tissue based screening technologies based on ex-vivo tissues and reaggregated 3D systems.

200 Western Avenue Cardiff, Wales, CF5 2YB United Kingdom

16-20 Regent Street Cambridge CB2 1DB United KingdomFounded in 2010, Cogentia is a healthcare consulting company based in Cambridge in the UK. We provide market access skills, knowledge and expertise to the pharmaceutical, biotech and device industries. We help our clients to identify, understand and overcome the wide-ranging market access challenges that emerge throughout the life-cycle of their products. With a strong combination of public sector, industry and consulting experience we are able to deliver genuine insights across multiple stakeholder perspectives ensuring that our clients get both the highest quality research and the know-how to make it count.

University of Leicester Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LXThe CCLG Tissue Bank is the UK’s largest unique collection of tumour, DNA and other tissue samples from childhood cancer patients. Tissue samples from the CCLG Tissue Bank gives scientists the chance to get as close to the disease as possible – so they can find new diagnostic methods, treatments and cures for childhood cancers. As well as access to tissue, scientists can request anonymised data linked to the sample, including if the donor’s cancer has progressed and the treatments they have received.

Unit 25 Kenfig Industrial Estate Margam Port Talbot SA13 2PE United KingdomCeltic Chemicals supplies minerals and vitamins.

Church Road Toft England, CB23 United KingdomWe are a leading product and technology innovation partner focused on helping our customers realise new opportunities. Specialising in the healthcare, consumer, and industrial equipment sectors, our solutions start at the point a business decides upon the need for innovation and finish with the launch of a breakthrough new product that is customer focused and commercially effective. Our product development and prototype manufacturing quality systems are certified to ISO 13485/9001.

Church Road Toft Cambridge, CB23 2RF United KingdomWe are a leading product and technology innovation partner focused on helping our customers realise new opportunities. Specialising in the healthcare, consumer, and industrial equipment sectors, our solutions start at the point a business decides upon the need for innovation and finish with the launch of a breakthrough new product that is customer focused and commercially effective. Our product development and prototype manufacturing quality systems are certified to ISO 13485/9001.

Park Place Cardiff, Wales, CF10 United Kingdom

Unit G Perram Works Merrow Lane Guildford GU4 7BN United KingdomClin-Tech provides manufacture and sale of reagents, stains, and diagnostic kits.

Holm Street Strathaven Lanarkshire ML10 6NB Scotland UKCrawford Scientific provides chromatography consumables, analytical services, chromatography, spectrometry, and environmental analysis.

Chilterns House Dean Street Marlow SL7 3AA UKCuro Consulting provides highly differentiated value communication solutions to the Pharmaceutical sector, enabling our clients to discuss the value and return on investment proposition to their new therapies with budget holders in state and private health services. With over a decade’s experience in the wider consulting industry, Curo offers a new perspective and a different approach to Market Access. Well respected in the industry, we pride ourselves on thinking beyond the usual parameters of the pharma world. True, we have a team of Health Economics experts and specialist software builders, but we are not data processors, nor a software company. Instead, we use our resources to build narratives that speak to Payers and answer their questions; helping you to show that it’s value that matters, not cost. Curo are also proud winners of The Queen’s Award for Enterprise – International Trade, 2015, the UK’s highest accolade for business success.

Curo Consulting Ltd, 49-51 Dean Street United Kingdom MARLOW, Buckinghamshire, SL7 3AA United KingdomCuro Consulting provides highly differentiated value communication solutions to the Pharmaceutical sector, enabling our clients to discuss the value and return on investment proposition to their new therapies with budget holders in state and private health services. With over a decade’s experience in the wider consulting industry, Curo offers a new perspective and a different approach to Market Access. Well respected in the industry, we pride ourselves on thinking beyond the usual parameters of the pharma world. True, we have a team of Health Economics experts and specialist software builders, but we are not data processors, nor a software company. Instead, we use our resources to build narratives that speak to Payers and answer their questions; helping you to show that it’s value that matters, not cost. Curo are also proud winners of The Queen’s Award for Enterprise – International Trade, 2015, the UK’s highest accolade for business success.

Nucleus The Bridge, Brunel Way, Dartford Kent DA1 5GA United KingdomCogtest provides the latest developments in cognitive neuroscience to the measurement of cognitive function in clinical trials.

Dean Row Court Summerfields Village Centre Wilmslow Cheshire SK9 2TA United KingdomChemQuest Limited has re-invented the concept of third-party sourcing and procurement. We are the UK’s leading specialist in purchasing for Research and Development within the chemical, fine chemical and pharmaceutical industries.

1S Summerfield Village Centre/Dean Row Rd Wilmslow, SK9 2TA United KingdomChemQuest Limited has re-invented the concept of third-party sourcing and procurement. We are the UK’s leading specialist in purchasing for Research and Development within the chemical, fine chemical and pharmaceutical industries.

James Lindsay Place, Dundee Technopole Dundee, DD1 5JJ U.K.CXR Biosciences provides preclinical services and expertise, specialising in investigative toxicology, exploratory and discovery toxicology, metabolism and pharmacokinetics.

2 James Lindsay Place Dundee Technopole Dundee Scotland , DD1 5JJ United KingdomCXR Biosciences provides preclinical services and expertise, specialising in investigative toxicology, exploratory and discovery toxicology, metabolism and pharmacokinetics.

9400 Garsington Road Oxford Business Park Oxford UK OX4 2HNCyclofluidic is using CyclOps™, its proprietary drug discovery platform, to revolutionise hit-to-lead optimisation. CyclOps™ connects chemistry, purification, screening and drug design with complex algorithms allowing drug lead molecules to be assayed minutes, rather than weeks, after they are designed. Using the power of flow or batch chemistry, our unique approach puts synthesis, screening and molecular design firmly back together in a single laboratory allowing fast iterative exploration of vast areas of diverse chemical space. CyclOps™ is the ultimate lean approach to lead discovery, allowing us to optimise hits in real time, making and screening only those key compounds that progress a hypothesis towards the best possible lead molecules.

BioPark Broadwater Road Welwyn Garden City, Hertfordshire AL7 3AX United KingdomCyclofluidic is using CyclOps™, its proprietary drug discovery platform, to revolutionise hit-to-lead optimisation. CyclOps™ connects chemistry, purification, screening and drug design with complex algorithms allowing drug lead molecules to be assayed minutes, rather than weeks, after they are designed. Using the power of flow or batch chemistry, our unique approach puts synthesis, screening and molecular design firmly back together in a single laboratory allowing fast iterative exploration of vast areas of diverse chemical space. CyclOps™ is the ultimate lean approach to lead discovery, allowing us to optimise hits in real time, making and screening only those key compounds that progress a hypothesis towards the best possible lead molecules.

Welwyn Garden City, England United KingdomCyclofluidic is using CyclOps™, its proprietary drug discovery platform, to revolutionise hit-to-lead optimisation. CyclOps™ connects chemistry, purification, screening and drug design with complex algorithms allowing drug lead molecules to be assayed minutes, rather than weeks, after they are designed. Using the power of flow or batch chemistry, our unique approach puts synthesis, screening and molecular design firmly back together in a single laboratory allowing fast iterative exploration of vast areas of diverse chemical space. CyclOps™ is the ultimate lean approach to lead discovery, allowing us to optimise hits in real time, making and screening only those key compounds that progress a hypothesis towards the best possible lead molecules.

The Centre for Innovation and Enterprise BEGBROKE SCIENCE PARK Oxford, England, OX5 1PF United KingdomCortex Organics is a cutting edge organic synthesis spin-out from the University of Oxford dedicated to supporting the life sciences industry. We specialise in custom synthesis and route development to support the life sciences industries. Highly cost and time competitive.

2 Hinksey Court Church Way Oxford , Oxfordshire , OX2 9SX United KingdomCortex Organics is a cutting edge organic synthesis spin-out from the University of Oxford dedicated to supporting the life sciences industry. We specialise in custom synthesis and route development to support the life sciences industries. Highly cost and time competitive.

Cambridge research Biochemicals Limited 17-18 Belasis Court, Belasis Hall Technology Park Billingham, Cleveland, England, TS23 4AZ United KingdomCambridge Research Biochemicals provides chemical synthesis of peptides, the custom production of polyclonal and monoclonal antibodies and labelling services.

12 Union Road Cambridge. CB2 1EZ UKCambridge Crystallographic Data Center offers x-ray crytallography.

Heath Park Wales, CF14 4UJ United KingdomCellesce is a UK-based biotech CDMO with a global leadership position in the scale-up and manufacturing of Patient-Derived Organoids (PDOs) for use in drug discovery and development. We have developed a novel bioprocess workflow utilising unique bioreactors for scaled up and controlled manufacture of patient derived organoids (PDOs) and xenograft derived organoids (PDX-Os) for their use in high throughput applications earlier in drug discovery. Cellesce is already a revenue generating company. The main projects we are currently executing for customers including large pharma, biotechs and organ-on-chip organisations include: * Scale up of high quality PDOs that we have commercially available within our PDO product portfolio. * Scale up of high quality PDOs or PDX derived organoids that our clients have generated or sourced through biobanks. * Source, develop and validation of new PDO or PDX-O lines from particular tissues or patient donors which are bioprocess-expanded by Cellesce for our client’s specific research projects. Examples of end uses include applications such as organ-on-a-chip, high throughput compound screening, 3D high content imaging, CRISPR studies and leveraging organoids with other cells in complex in-vitro assays such as I/O. We are also implementing organoid quality systems, as a key step change from the current organoid ecosystem predominantly still in academia. These QC/QA measures allow Cellesce to continue to develop the processes that ensure that our final PDO products we manufacture are reproducible and consistent, biologically fit for purpose, “gold standard” research tools that can support the increasing quality demands from customers and the wider regulatory environment as we industrialise and pioneer the use of biorelevant organoids in high throughput drug discovery and development by large pharma and biotechs.

Cardiff Medicentre Heath Park, Cardiff, CF14 4UJ United KingdomCellesce is a UK-based biotech CDMO with a global leadership position in the scale-up and manufacturing of Patient-Derived Organoids (PDOs) for use in drug discovery and development. We have developed a novel bioprocess workflow utilising unique bioreactors for scaled up and controlled manufacture of patient derived organoids (PDOs) and xenograft derived organoids (PDX-Os) for their use in high throughput applications earlier in drug discovery. Cellesce is already a revenue generating company. The main projects we are currently executing for customers including large pharma, biotechs and organ-on-chip organisations include: * Scale up of high quality PDOs that we have commercially available within our PDO product portfolio. * Scale up of high quality PDOs or PDX derived organoids that our clients have generated or sourced through biobanks. * Source, develop and validation of new PDO or PDX-O lines from particular tissues or patient donors which are bioprocess-expanded by Cellesce for our client’s specific research projects. Examples of end uses include applications such as organ-on-a-chip, high throughput compound screening, 3D high content imaging, CRISPR studies and leveraging organoids with other cells in complex in-vitro assays such as I/O. We are also implementing organoid quality systems, as a key step change from the current organoid ecosystem predominantly still in academia. These QC/QA measures allow Cellesce to continue to develop the processes that ensure that our final PDO products we manufacture are reproducible and consistent, biologically fit for purpose, “gold standard” research tools that can support the increasing quality demands from customers and the wider regulatory environment as we industrialise and pioneer the use of biorelevant organoids in high throughput drug discovery and development by large pharma and biotechs.

Digital Bio pharm LTD 145-157 St. John Street London, UK EC1V 4PWDigital BioPharm offers in silico drug discovery and hit to lead optimization services.

Kemp House 152 City Road London, EC1V 2NX United KingdomDigital BioPharm offers in silico drug discovery and hit to lead optimization services.

Sansaw Business Park, Hadnall, Shrewsbury, Shropshire SY4 4ASDechra provides veterinary products for endocrinology, dematology, and cardiology.

Wrecclesham House Wrecclesham Road Farnham GU10 4PS United Kingdom DXS International has been providing clinical decision support to the primary care and retail pharmacy sectors in the UK for the past ten years. DXS has a range of products that enables healthcare stakeholders, such as Primary Care Organisations, Pharmaceuticals, Healthcare Educators, Service Providers and many more to provide pertinent information regarding patient treatment to a busy clinician in the workflow. The result is improved outcomes delivered cost effectively. DXS achieves this through its standard DXS Point of Care platform which integrates with any patient record system and delivers content relevant to the patient’s condition during the consultation. This is why 20,000 GPs and 4,500 retail pharmacies have DXS in the UK.

Wrecclesham Road Wrecclesham, England, GU10 4PS United Kingdom DXS International has been providing clinical decision support to the primary care and retail pharmacy sectors in the UK for the past ten years. DXS has a range of products that enables healthcare stakeholders, such as Primary Care Organisations, Pharmaceuticals, Healthcare Educators, Service Providers and many more to provide pertinent information regarding patient treatment to a busy clinician in the workflow. The result is improved outcomes delivered cost effectively. DXS achieves this through its standard DXS Point of Care platform which integrates with any patient record system and delivers content relevant to the patient’s condition during the consultation. This is why 20,000 GPs and 4,500 retail pharmacies have DXS in the UK.

2 Royal College StreetLondon NW1 0NH United KingdomdeltaDOT is a spin out company from Imperial College London UK - a team of scientists and engineers dedicated to the advancement of analytical techniques using patented methods and instrumentation in High Performance Capillary Electrophoresis (HPCE). We design and produce HPCE instruments which we are marketing worldwide. We also use the same instruments to offer Analytical Services and Contract Research. Our offices and laboratories are based in the London Bioscience Innovation Centre (LBIC). High Performance Capillary Electrophoresis (HPCE) analytical instruments are designed, manufactured and marketed by deltaDOT. These instruments use deltaDOT’s proprietary imaging and analysis technology called Label Free Intrinsic Imaging (LFII®). High Performance Capillary Electrophoresis and Label Free Intrinsic Imaging applied to a CE analytical system offers dramatically improved discovery power in comparison to other conventional CE systems. deltaDOT team of scientists has developed considerable expertise in CE based analysis and in solving clients’ analytical problems. Using our own HPCE LFII® analytical instruments we also offer Analytical Services and Contract Research to industry and academia from our laboratories in the London Bioscience Innovation Centre

London BioScience Innovation Centre 2 Royal College St, Kings Cross London, NW1 0NH United KingdomdeltaDOT is a spin out company from Imperial College London UK - a team of scientists and engineers dedicated to the advancement of analytical techniques using patented methods and instrumentation in High Performance Capillary Electrophoresis (HPCE). We design and produce HPCE instruments which we are marketing worldwide. We also use the same instruments to offer Analytical Services and Contract Research. Our offices and laboratories are based in the London Bioscience Innovation Centre (LBIC). High Performance Capillary Electrophoresis (HPCE) analytical instruments are designed, manufactured and marketed by deltaDOT. These instruments use deltaDOT’s proprietary imaging and analysis technology called Label Free Intrinsic Imaging (LFII®). High Performance Capillary Electrophoresis and Label Free Intrinsic Imaging applied to a CE analytical system offers dramatically improved discovery power in comparison to other conventional CE systems. deltaDOT team of scientists has developed considerable expertise in CE based analysis and in solving clients’ analytical problems. Using our own HPCE LFII® analytical instruments we also offer Analytical Services and Contract Research to industry and academia from our laboratories in the London Bioscience Innovation Centre

Discovery Park, Ramsgate Rd, Sandwich , Kent, CT13 9FF United KingdomDrug Development Solutions is a contract research organisation (CRO) offering GLP and GCP bioanalysis of small molecules, large proteins for pharmacokinetics, biomarkers and immunogenicity. We also provide cGMP analytical sciences research and testing services, consultancy and quality control solutions to support Chemistry Manufacturing and Control (CMC) requirements at all stages of the drug development pipeline from discovery through preclinical and clinical development to commercial manufacture. Our Cambridge (Fordham) site is one of the largest bioanalytical centres in the world. The site employs around 380 scientists operating from 8,000m2 purpose-built, state-of-the-art analytical labs.

Newmarket Rd Fordham, Ely Cambridge, Cambridgeshire, CB7 5WW United KingdomDrug Development Solutions is a contract research organisation (CRO) offering GLP and GCP bioanalysis of small molecules, large proteins for pharmacokinetics, biomarkers and immunogenicity. We also provide cGMP analytical sciences research and testing services, consultancy and quality control solutions to support Chemistry Manufacturing and Control (CMC) requirements at all stages of the drug development pipeline from discovery through preclinical and clinical development to commercial manufacture. Our Cambridge (Fordham) site is one of the largest bioanalytical centres in the world. The site employs around 380 scientists operating from 8,000m2 purpose-built, state-of-the-art analytical labs.

Mountjoy Research Centre Block 2 Stockton Road Durham, DH1 3UP United KingdomDurham University focuses on research in various areas.

6 Coventry Avenue, Great Sutton, Ellesmere Port, Cheshire, CH66 2GL UK

Hardwick Road, Astmoor, Runcorn, Cheshire, UK, WA7 1PHDCC Health and Beauty Solutions specializes in the global health and beauty market manufacturing tablets and softgels.

Diamond House, Harwell Science and Innovation Campus Fermi Avenue, Chiltern, Didcot, Oxfordshire OX11 0QX, United KingdomDiamond Light Source is the UK’s national synchrotron science facility.

Didcot, England, OX11 United KingdomDiamond Light Source is the UK’s national synchrotron science facility.

Dawson Road Mount Farm Bletchley Milton Keynes Buckinghamshire MK1 1JNDeli 24 are the first UK Contract Processing Facility to offer High Pressure Processing. We are a privately owned company with extensive management experience in the creation and successful operation of innovative manufacturing processes.

11 Stuart Green, Edinburgh, Scotland EH12 8YF United KingdomFountainbridge offers custom synthesis services for pharmaceutical intermediates, labelled compounds, and R&D chemicals

Woodside Bishop's Stortford Herts CM23 5RG UKFisher Bioservices offers biorepository and biobanking services, clinical trial sample management, specimen processing, DNA/RNA extraction, and PCR/QPCR services including WGA PCR, cell therapy storage and logistics, and biologic API transport, storage and handling.

No.4 East Wing Gemini House Flex Meadow Harlow, Essex CM19 5TJ United KingdomDiamond Pharma Services is a group of companies offering consulting services to support regulatory affairs and product development in the EU and US. Diamond BioPharm Ltd provides consultancy services in European regulatory affairs and product development to the biotech and pharmaceutical industries. The company was founded in 2005 under the leadership of Dr. Maureen Graham (ex. Amgen, MSD, Glaxo & IVAX). The team Dr Graham has established includes those with a broad and varied industry experience and former regulators, offering both breadth and depth of expertise, from which our clients can benefit. Our many years of industry experience and expertise is across a broad range of therapeutic areas and product types (biotechnology including monoclonal antibodies, gene-therapy and new chemical entities - both innovative and generics). The entire team has significant experience and knowledge of European regulatory procedures (national, mutual recognition, decentralised and centralised) and an in-depth awareness of current legislation and industry trends. Diamond BioPharm consultants have extensive experience of assisting clients with regulatory support from early stages of product development through to achievement of marketing authorisations, orphan designations, scientific advice and have also assisted with the maintenance of marketing authorisations through variations, and monitoring and updating of prescribing information. Diamond BioPharm Ltd was awarded TOPRA Innovation Award 2013 for supporting the first gene therapy product approval in Europe. Diamond Pharma Services, Inc. provides consultancy services in US regulatory affairs and product development to the biotech and pharmaceutical industries. The company was founded in 2015 as a subsidiary of Diamond BioPharm Ltd. Diamond Pharma Services, Inc. consultants have extensive experience of assisting clients with regulatory support from early stages of product development and IND initiation through to achievement of marketing authorisations, orphan designations and successful FDA meetings.

No.4 East Wing Gemini House, Flex Meadow Harlow, CM19 5TJ United KingdomDiamond Pharma Services is a group of companies offering consulting services to support regulatory affairs and product development in the EU and US. Diamond BioPharm Ltd provides consultancy services in European regulatory affairs and product development to the biotech and pharmaceutical industries. The company was founded in 2005 under the leadership of Dr. Maureen Graham (ex. Amgen, MSD, Glaxo & IVAX). The team Dr Graham has established includes those with a broad and varied industry experience and former regulators, offering both breadth and depth of expertise, from which our clients can benefit. Our many years of industry experience and expertise is across a broad range of therapeutic areas and product types (biotechnology including monoclonal antibodies, gene-therapy and new chemical entities - both innovative and generics). The entire team has significant experience and knowledge of European regulatory procedures (national, mutual recognition, decentralised and centralised) and an in-depth awareness of current legislation and industry trends. Diamond BioPharm consultants have extensive experience of assisting clients with regulatory support from early stages of product development through to achievement of marketing authorisations, orphan designations, scientific advice and have also assisted with the maintenance of marketing authorisations through variations, and monitoring and updating of prescribing information. Diamond BioPharm Ltd was awarded TOPRA Innovation Award 2013 for supporting the first gene therapy product approval in Europe. Diamond Pharma Services, Inc. provides consultancy services in US regulatory affairs and product development to the biotech and pharmaceutical industries. The company was founded in 2015 as a subsidiary of Diamond BioPharm Ltd. Diamond Pharma Services, Inc. consultants have extensive experience of assisting clients with regulatory support from early stages of product development and IND initiation through to achievement of marketing authorisations, orphan designations and successful FDA meetings.

49 Peter Street Manchester, M2 3NG United KingdomDeepMed IO Ltd provides AI-related software development services to the Life Sciences and Pharmaceutical industries. Past projects include predictive models linking genomic in-vitro data to drug efficacy in real patient cohorts and region-of-interest identification in oncology digital pathology images.

Med IC4, Keele University Science and Business Park, Keele, Staffordshire, ST5 5NL United KingdomDermal Technology Laboratory specialises in in-vitro dermal absorption studies that are needed as part of the safety testing of new and existing chemicals, agrochemicals, personal care, and pharmaceutical products. Data are used to predict human exposure following contact with the skin.

1-2 Thorley Hall Stables Bishop's Stortford Herts CM23 4BE UNITED KINGDOMDotmatics offers compound sourcing, analytics, chemical libraries, structure elucidation, and assay reporting.

England United KingdomDotmatics offers compound sourcing, analytics, chemical libraries, structure elucidation, and assay reporting.

Monmouth House 38 Artillery Lane London E1 7LS United KingdomDeallus provides offerings to support strategy development and decision making in life-science organizations.

Unit 20, Howard Way Interchange Park, Newport Pagnell, Buckinghamshire MK16 9QS, United KingdomDJB Labcare provides servicing for centrifuges and incubators.

Newport Pagnell, England, MK16 United KingdomDJB Labcare provides servicing for centrifuges and incubators.

145-157 St. John Street London,UK EC1V4PWDigitalBioPharm ltd is consulting company, working in the field of biomedicine. Our main philosophy – IT-solutions usage in drug discovery and biotechnology. Our services include: preclinical drug discovery, virtual prediction of molecular docking, QSAR, medical 3D animation, venture investments consulting and due dilligence.

145-157 Saint John Street London, England, EC1V 4PW United KingdomDigitalBioPharm ltd is consulting company, working in the field of biomedicine. Our main philosophy – IT-solutions usage in drug discovery and biotechnology. Our services include: preclinical drug discovery, virtual prediction of molecular docking, QSAR, medical 3D animation, venture investments consulting and due dilligence.

72 York Terrace United Kingdom Cambridge, Cambridgeshire, CB1 2PR United KingdomWe work with Pharmaceutical and Biotech companies to ensure their analytical functions outperform the demands and objectives of modern drug discovery. Consulting services encompass the conduct of operational reviews, mitigating resource or expertise shortages with in-laboratory-based support, training and bespoke software/automation solutions.

84 Castle Street Glasgow, G4 0SF United KingdomDrug Delivery International (DDi) specializes in drug formulation for controlled release systems in application of cardiovascular medicine, colon targeted delivery, morning stiffness, and sleep maintenance.

Units 13-14 Swan Business Park Sandpit Road Dartford Kent DA1 5ED ENGLANDDavid Norris Analytical Laboratories was founded in September 2005 by David and Kirsty Norris. David set up DNAL to provide a specialist service to the Agrochemical Industry. The business is a family Company, established and wholly owned by David and Kirsty Norris. Over the years our team has continued to grow steadily in size and experience and we have invested heavily in a variety of new technologies to offer first class analytical services to meet our Clients needs both now and in the future. We have doubled our laboratory floor space recently and have the capacity to continue to grow and take on new projects to meet demand.

3 Betton Way Moretonhampstead, England, TQ13 8JA United KingdomDarr House Molecular Innovation was established by Alistair Miller to specialise primarily in the innovation and design of bespoke fluorinated intermediates. In addition, we offer a range of custom synthesis and contractual research opportunities to the agrochemical and pharmaceutical industries, biotech and catalogue companies.

Room 00.36a, Hawthorn Building Leicester, LE1 9BH United KingdomDMBioscience offers ADME in hepatocytes, liver cell lines, and recombinant P450 enzymes, protein expression, protein kinase assays, receptor assays, and FACS analysis services.

Bursledon Hall, Blundell Lane, Southampton, SO31 1AA, U.K.Established in 1981, the Drug Safety Research Unit (DSRU) monitors, studies and communicates the safety and risk management of medicines. The DSRU has evolved into a broad pharmacoepidemiological unit. Aim Our aim is to achieve the highest possible scientific and ethical standards,by putting the interests of patients first and to work with integrity and fairness with all our partners. Risk management Through our historical links with doctors in the NHS, the unit conducts observational studies in both primary and secondary care, many of which are Post-authorisation Safety Studies (PASS) which are part of Risk Management Plans (RMPs) in Europe. Pharmacovigilance Our activities are principally concerned with pharmacovigilance, that is, the detection of side-effects associated with the use of marketed drugs. The DSRU undertakes all forms of research studies and evaluations of the safety of medicines and provides education and training in pharmacovigilance and related subjects. Independent Scientific Excellence The DSRU is an independent unit providing scientific excellence demonstrated through conducting clinical research database studies which are used to support public health decisions and production of publications in international peer reviewed journals since 1980. The DSRU makes significant,valuable contributions in the area of post marketing surveillance of pharmaceutical products. We have achieved both recognition and endorsement by the regulatory authorities, healthcare professionals and pharmaceutical industry worldwide.

Cart House 2, Copley Hill Business Park, Cambridge Road Babraham Cambridge, Cambridgeshire, CB22 3GN United Kingdom3DConsultants provide scientific consultancy, due diligence services and project management as well as support in helping you to start or sell your company. Our business model is based upon the partnership’s capability of providing a specialist solution for those looking for expert advice and support across all aspects of the drug discovery and development process. We are able to achieve this through deploying a team of highly experienced scientists with core competencies across a broad range of disciplines including in vitro/in vivo biology, medicinal chemistry, DMPK, pre-clinical development (CMC, tox, scale-up) through clinical development (operations, management, regulatory). With more than a hundred years of collective experience in both biotech and pharma across the discovery and development spectrum, our team has the skill sets and experience to provide practical, cost-efficient and timely solutions to your project through consultation on an individual basis or as a team.

2 Harding Way England, CB4 3RR United KingdomProvide technical and managerial consultancy services to the biopharmaceutical industry.

2 HARDING WAY CAMBRIDGE, CAMBRIDGESHIRE, CB43RR United KingdomProvide technical and managerial consultancy services to the biopharmaceutical industry.

19 Church Street Warwick, England CV34 4AB United KingdomDCA Design International offers medicine device, diagnostic, and scientific instrument design and development services.

Portsdown Hill Road, Fareham, Hampshire, PO17 6AD United KingdomWhat we do The Defence Science and Technology Laboratory (Dstl) ensures that innovative science and technology contribute to the defence and security of the UK. We supply specialist services to the Ministry of Defence (MOD) and wider government. 60% of MOD’s science and technology programme (total funding: £410 million) is supplied by our external partners in industry and academia worldwide. Who we are As a trading fund of MOD, Dstl is run along commercial lines. It is one of the principal government organisations dedicated to science and technology in the defence and security field. Our Centre for Defence Enterprise (CDE) is the point of contact for suppliers with innovative ideas to bid for proof-of-concept research funding. Dstl’s specialist facilities are available for use by other government departments and non-government organisations. The indoor ballistics range offers a small-arms ballistics and fragment firing capability to assess the ballistic effects of weapon performance; the UK Home Made Explosives (HME) facility carries out research to counter the threat from improvised or home made explosives; our secure waste disposal facility, the Destructor Complex, provides a specialist disposal solution for hazardous or high security waste materials.

PO Box 45 Manchester. M11 1XD. UKDatesand provides products and equipment for biotechnology and horticultural industries.

Manchester, England United KingdomDatesand provides products and equipment for biotechnology and horticultural industries.

London, United KingdomOur expertise is antibody humanization. The founders have humanized >40 therapeutic candidates. Our royalty-free design service is individually tailored to your needs and budget.

Dyecor Limited Whitestone Business Park Whitestone Hereford HR13SEDyecor provides manufacturing of sachets, wipes, and medical packaging.

Whitestone, England, HR1 United KingdomDyecor provides manufacturing of sachets, wipes, and medical packaging.

Suite 4, De Walden Court 85 New Cavendish Street London W1W 6XD United KingdomDishman CRAMS offers development services, kilo supply, cGMP pilot production and full scale cGMP manufacture.

Science and Technology Centre Earley Gate Whiteknights Road Reading RG6 6BZ United KingdomDextra are carbohydrate specialists with an international reputation in all areas of research, synthesis and analysis of carbohydrates and complex sugars.

Cardiff House Priority Business Park, Cardiff Road Cardiff, Barry, Vale Of Glamorgan, CF63 2AW United KingdomDonate For Research Initiative is a UK Based NHS approved Research Tissue Bank. Its goal is to engage with people using the NHS to invite them to participate in biomedical research by donating waste tissue, blood etc (so called bio-samples) support ethically approved research projects. Such kind donations help drive biomedical research to help the research community advance our understanding of human disease and improve the medical diagnosis, treatment and outcome for future generations.

great barton Great Barton, England, IP31 2RU United KingdomDragon Pharmacology provides research models for various diseases. Dragon Pharmacology is a trusted *TEST* vendor for pharmacological animal models and the Best Service Ever . **Test Company for Demos**

Chesterford Research Park Little Chesterford Saffron Walden, Essex, Cb10 1xl United KingdomDomainex offers a range of services in the following fields: - Protein expression and characterisation, including using a proprietary gene fragmentation technology known as Combinatorial Domain Hunting (CDH) to generate up to 100K constructs of a soluble target of interest - Structural biology and X-ray crystallography - Assay development and compound screening - Computer-Aided Drug Design (CADD) - Virtual screening - Integrated fragment-based drug discovery, including screening my microscale thermophoresis - Hit-to-lead and lead optimization medicinal chemistry - Bioanaytical method development

Little Chesterford Little Chesterford, England, CB10 1XL United KingdomDomainex offers a range of services in the following fields: - Protein expression and characterisation, including using a proprietary gene fragmentation technology known as Combinatorial Domain Hunting (CDH) to generate up to 100K constructs of a soluble target of interest - Structural biology and X-ray crystallography - Assay development and compound screening - Computer-Aided Drug Design (CADD) - Virtual screening - Integrated fragment-based drug discovery, including screening my microscale thermophoresis - Hit-to-lead and lead optimization medicinal chemistry - Bioanaytical method development

Little Chesterford Little Chesterford, England, CB10 1XL United KingdomDomainex offers a range of services in the following fields: - Protein expression and characterisation, including using a proprietary gene fragmentation technology known as Combinatorial Domain Hunting (CDH) to generate up to 100K constructs of a soluble target of interest - Structural biology and X-ray crystallography - Assay development and compound screening - Computer-Aided Drug Design (CADD) - Virtual screening - Integrated fragment-based drug discovery, including screening my microscale thermophoresis - Hit-to-lead and lead optimization medicinal chemistry - Bioanaytical method development

28 Hanbury St. London, E1 6QR United KingdomDesktop Genetics is a UK biotechnology company that imagines and creates intuitive software solutions and high performance assays for genome editing experiments.

Babraham Research Campus CB22 3AT United KingdomDefiniGEN provide a wide range of terminally differentiated human cell products including mature hepatocytes, pancreatic cells, intestinal organoids and cholangiocytes derived from induced pluripotent stem cells (iPSC) to the life science and drug discovery sectors, using our proprietary OptiDIFF platform. The OptiDIFF protocol has been developed over many years by Prof Ludovic Vallier's group at Cambridge University and has been widely published upon, and allows us to generate large quantities of terminally differentiated, phenotypically relevant human cells for target validation or screening. It allows us to robustly achieve good quality human like cells at scale to support medium throughput screening initiatives. We use this same technology to generate a range of unique innovative human cell disease models. We can employ one of two routes to achieve this; firstly we can take fibroblasts from a diseased donor, reprogram to iPS then differentiate into large quantities of diseased human cells which would have a complete donor genetic background. Secondly we can use a healthy wild type iPSC line and employ CRISPR to edit the genome and generate many different functional disease models. Examples include NAFLD (PNPLA3), Alpha1-antitrypsin disorder, GSD1a, familial hypercholesterolemia, amyloidosis, Wilson's disease, Gaucher's disease or Crigler Najar in hepatocytes. In pancreatic cells we offer models for MODY3 (monogenic diabetes - HNF1alpha), neonatal diabetes (KCNJ11) and cystic fibrosis (dF508) but the flexibility of CRISPR allows us to knock in or out a wide range of genes to generate a comprehensive suite of diseased model cell products.

Babraham Research Campus Moneta Building Babraham , Cambridge , CB22 3AT United KingdomDefiniGEN provide a wide range of terminally differentiated human cell products including mature hepatocytes, pancreatic cells, intestinal organoids and cholangiocytes derived from induced pluripotent stem cells (iPSC) to the life science and drug discovery sectors, using our proprietary OptiDIFF platform. The OptiDIFF protocol has been developed over many years by Prof Ludovic Vallier's group at Cambridge University and has been widely published upon, and allows us to generate large quantities of terminally differentiated, phenotypically relevant human cells for target validation or screening. It allows us to robustly achieve good quality human like cells at scale to support medium throughput screening initiatives. We use this same technology to generate a range of unique innovative human cell disease models. We can employ one of two routes to achieve this; firstly we can take fibroblasts from a diseased donor, reprogram to iPS then differentiate into large quantities of diseased human cells which would have a complete donor genetic background. Secondly we can use a healthy wild type iPSC line and employ CRISPR to edit the genome and generate many different functional disease models. Examples include NAFLD (PNPLA3), Alpha1-antitrypsin disorder, GSD1a, familial hypercholesterolemia, amyloidosis, Wilson's disease, Gaucher's disease or Crigler Najar in hepatocytes. In pancreatic cells we offer models for MODY3 (monogenic diabetes - HNF1alpha), neonatal diabetes (KCNJ11) and cystic fibrosis (dF508) but the flexibility of CRISPR allows us to knock in or out a wide range of genes to generate a comprehensive suite of diseased model cell products.

Drumlanrig, Great Saxham, Bury st.Edmunds, suffolk, IP29 5JR, UKDewar Crop Protection Ltd. offers the comprehensive crop protection service, from field trials to advisory leaflets. For chemical companies: Development and pre-sales trials on a wide range of crops Environmental assessments including impact on non-target organism in the environment. For product marketing: Images for advisory and marketing materials from print to presentations and websites Up-to-date expertise to ensure your messages are accurate and compelling. For universities and colleges: Courses on current crop protection methods in the UK and Europe Assistance in writing and editing papers and reports

Skipton, North Yorkshire BD23 2RW, England,Dales Pharmaceuticals specializes in manufacturing and packing of pharmaceticals.

Stevant Way, Morecambe, Lancashire LA3 3PU, United KingdomWe are the UK's leading specialist in the manufacture, filling and packaging of bespoke sachets, bottles and tubes. Offering a complete service from concept creation to delivery of market ready products.

70 St. Mary Axe London, EC3A 8BE United KingdomDRG is the premier provider of healthcare analytics, data and insight products and services to the worlds leading pharmas, biotech and medical technology companies.

Friars House, 160 Blackfriars Road London, SE1 8EZ United KingdomDRG is the premier provider of healthcare analytics, data and insight products and services to the worlds leading pharmas, biotech and medical technology companies.

6 Talisman Road England, OX26 6HR United KingdomDRG is the premier provider of healthcare analytics, data and insight products and services to the worlds leading pharmas, biotech and medical technology companies.

James Lindsay Place Dundee Technopole Dundee DD1 5JJDundee Cell Products offers antibody, DNA cloning, cell line, immunohistochemistry, mass spectrometry, and cell marker services.

Dundee, Scotland United KingdomDundee Cell Products offers antibody, DNA cloning, cell line, immunohistochemistry, mass spectrometry, and cell marker services.

Exeter Science Park 6 Babbage Way Clyst Honiton, Exter, EX5 2FN United KingdomDECIPHEX ACCELERATES CERTAINTY IN PATHOLOGY SERVICE DELIVERY BY NETWORKING PATHOLOGISTS AND USING ARTIFICIAL INTELLIGENCE TO DRIVE EFFICIENT, HIGH-QUALITY REPORTING. Patholytix is the industry-leading digital pathology workflow & integrated AI platform for Research Pathology. Patholytix is trusted by the leading CROs and pharmaceutical companies for handling high volume drug safety pathology studies, providing a complete GLP-compliant workflow with integrated AI screening capabilities. Diagnexia is an online clinical pathology department that provides on-demand access to remote subspecialty pathologists for primary diagnostics and secondary consult services, supporting the acceleration of diagnostic turnaround times and delivery of the highest quality of patient care.

James Lindsay Place Scotland, DD1 5JJ United KingdomDC Biosciences Ltd. provides pharmaceutical and biotech companies with cutting edge proteomics services to accelerate the development of safer drugs. We are best placed to apply our knowledge and experience in a wide range of bioscience disciplines including quantitative proteomics and bioinformatics to provide solutions in key areas of drug discovery and development. We have developed a quantitative proteomics-based technology portfolio that offers solutions to preclinical activities of the drug discovery process and developed new processes for biomarker discovery and validation, drug re-profiling and repositioning..

Hinxton, England, CB10 United KingdomThe EMBL-EBI maintains the world's most comprehensive range of molecular databases.

The Nanotechnology Centre Herschel Building Newcastle University Newcastle upon Tyne NE1 7RU UKEnviresearch provides the best regulatory and risk assessment service in Europe, for the global chemical industry. Enviresearch has years of expertise in the chemical area, and is committed to ensure that you are fully supported in all areas of chemical regulation. Enviresearch delivers expertise and compliance services in regulatory management and strategy, and Technical Services.

Holland Park, Holland Drive, Newcastle upon Tyne, NE2 4LZ, United Kingdome-Therapeutics focuses on drug discovery and development with the use of network pharmacology to quickly predict drug interactions and biological effects.

Suite 3, 15 Gosditch Street Cirencester, Gloucestershire, GL7 2AG UKEden Research plc is an AIM listed public company with intellectual property and expertise in encapsulation, terpenes and environmentally friendly technologies. We are developing these technologies through innovative research and a series of appropriate commercial production, marketing and distribution partnerships. Based near Oxford in the UK, we are developing natural solutions to agricultural, medical and industrial problems, with our primary focus being the innovative use of terpenes to create an exciting array of low-risk agricultural chemicals. Eden's products take advantage of the biocidal efficacy of naturally occurring chemicals produced by plant defence mechanisms and, in particular, the antimicrobial properties of terpenes. Terpenes are naturally occurring, low-toxicity botanical substances produced by most plants as part of their defence mechanisms. The initial Eden approach has involved the use of GRAS substances, that is, compounds 'Generally Regarded As being Safe' for human consumption or application to food crops.

9 Langley Road Durham, England, DH1 5LR United Kingdom My lab is involved in the studies of cognition and emotion in rats and mice exposed to novelty and open spaces.

20 Rosemount Road Ballynahinch N. Ireland BT24 8SYExploristics offers pharmacogenetics, biomarker analysis, pharmacovigilance, and modeling services.

North Street, Wicken Ely, Cambridge CB7 5XW United KingdomEuropa Bioproducts supplies various antibodies, proteins, cell products, and other reagents in addition to custom services including protein conjugation, antibody production, and glycan analytical services.

Glencorse Building Pentlands Science Park Bush Loan Penicuik Midlothian Scotland EH26 0PZ UKEPP is a OECD-GLP compliant CRO that provides core contract analytical, synthetic and environmental sciences services in support of worldwide generic agrochemical, human and veterinary pharmaceutical, and biocide registrations. Contract services include GLP compliant laboratory testing and reporting to recognised international standards in areas such as product chemistry (five batch, physico-chemical and storage stability testing of active ingredients and formulations), trial and production batch release, QC testing, mass spectroscopic (LC-MS-MS and GC-MS), quantitative and qualitative nuclear magnetic resonance (GLP-NMR) and custom synthesis (including stable labelled and radiochemical synthesis of active ingredients, impurities and metabolites) and GLP testing and certification of analytical reference standards. Recently introduced environmental sciences services includes ecotoxicity (aquatic and terrestrial) testing which enables us to offer a more complete suite of services underpinning REACH evaluations and submissions. Historical strengths lie in the areas of synthetic and analytical chemistry applied to process research, development and optimisation of manufacturing processes for trial batch and thereafter routine production of bulk fine chemicals (pharmaceutical and agrochemical intermediates and active ingredients) including Controlled Substances.

Enzyme Research Labs Ltd, Glamorgan House, Charter Court Enterprise Park Swansea, West Glamorgan, SA7 9DD United KingdomEnzyme Research Laboratories provides products for coagulation, antibodies, proteins, and venoms.

Unit 2 London Road Cambridge, CB22 3EG United KingdomFairJourney Biologics is a highly reputable service provider in the field of antibodies. It has entered into agreements with academia, biotech companies and Big pharma to systematically explore ground breaking targets and creating new ventures. Their Human Fab and llama VHH naïve libraries consistently yielded excellent panels of antibodies against difficult targets. The unrivalled experience in llama, mice, rat, rabbit and chicken antibody discovery contributes to position the company in the forefront of antibody discovery, engineering, characterisation and production.

82B High Street, Sawston, Cambs, CB22 3HJ United KingdomFairJourney Biologics is a highly reputable service provider in the field of antibodies. It has entered into agreements with academia, biotech companies and Big pharma to systematically explore ground breaking targets and creating new ventures. Their Human Fab and llama VHH naïve libraries consistently yielded excellent panels of antibodies against difficult targets. The unrivalled experience in llama, mice, rat, rabbit and chicken antibody discovery contributes to position the company in the forefront of antibody discovery, engineering, characterisation and production.

Food & Drug Analytical Services, Biocity, Pennyfoot Street, Nottingham, NG1 1GF, United KingdomFDAS was founded in 2004 to better address the third-party laboratory analytical needs of the pharmaceutical industry. Drawing on significant experience in pharmaceutical manufacturing and contract laboratory testing, our management team continues to develop an offering that is relevant to and integrates with the evolving pharma-CMO landscape. Quality Working in MHRA accredited facilities, FDAS conducts all analysis at its Nottingham cGMP facility. With a team of over 20 and a focus on training and retention, we therefore build and retain control of all aspects of quality management.

11 Market Street Hexham Northumberland NE46 3NS U.K.ePitope Informatics provides epitope prediction, protein analysis, and 3D structure analysis services.

Media House Adlington, Cheshire, SK10 4NL United KingdomAdvanced microscopy and characterisation services, including electron microscopy, confocal fluorescence microscopy, cell culture, chemical analysis and nanofabrication.

Alderley Park Alderley Edge, Cheshire, SK10 4TG United KingdomAdvanced microscopy and characterisation services, including electron microscopy, confocal fluorescence microscopy, cell culture, chemical analysis and nanofabrication.

1 Hameldown Rd Okehampton, EX20 1UB United KingdomThirty years ago Elemental Microanalysis Ltd was founded to offer a fast and accurate analytical service to the academic and industrial communities. We invite you to join a growing number of users who draw upon our experience in obtaining reliable results for carbon, hydrogen, nitrogen, oxygen and sulphur determination. Whether you have a single sample, or an on-going research program, we offer the same level of commitment to precision and accuracy. Our laboratory is fully accredited under ISO 17025 by the United Kingdom Accreditation Service (No. 4260). The schedule of accreditation covers the CHN OS analysis of organic substances. As well as offering a microanalysis service from our laboratory, Elemental Microanalysis Ltd produces elemental analyser consumables for all manufacturers and models from its ISO 9001 certified factory. As a leading independent specialist manufacturer of consumables and supplies for Elemental analysers, we offer products for both organic elemental analysis and inorganic elemental analysis by combustion or pyrolysis methods. Our consumables product range covers everything you need for the day-to-day operation of your analyser including tin capsules, silver capsules, combustion tubes and other quartz and glassware, combustion reagents, catalysts and standards, o-rings and seals, ceramic and graphite crucibles and much more. We support Elemental Analysers from Leco, Thermo/Carlo Erba, Perkin Elmer, Europa/Sercon, Exeter Analytical, Eltra, Horiba, Elementar, EuroVector, Costech, Shimadzu, Antek and others. Our products are available to order online, by telephone, fax or post.

77 Heyford Park Upper Heyford Oxfordshire OX25 5HD UKSpecialists in anti-peptide and antigen affinity purified goat polyclonal antibodies, Everest Biotech develop and manufacture high quality novel antibodies for the global biomedical research market.

Cherwell Innovation Centre 77 Heyford Park Upper Heyford, Oxfordshire, OX25 5HD United KingdomSpecialists in anti-peptide and antigen affinity purified goat polyclonal antibodies, Everest Biotech develop and manufacture high quality novel antibodies for the global biomedical research market.

UKThe European Collection of Authenticated Cell Cultures (ECACC) was established in 1985 as a cell culture collection to service the research community and provide an International Depository Authority recognised patent depository for Europe. Over the last 30 years ECACC has expanded and diversified to become one of the premier collections of authenticated cell cultures in the world and this remains the core of ECACC’s business. The collections currently hold over 40,000 cell lines representing 45 different species, 50 tissue types, 300 HLA types, 450 monoclonal antibodies and at least 800 genetic disorders. The development and maintenance of such a diverse collection has inevitably produced a high level of specialist knowledge and this, combined with the support of Public Health England, has enabled ECACC to position itself as a centre of expertise in all aspects of cell culture. ECACC has developed a comprehensive range of cell culture services and diversified into new product areas such as high quality genomic DNA extracted from cell lines. ECACC is one of the four collections of the Culture Collections of Public Health England. As has been the case since its inception, ECACC continues to operate out of the Porton Down site, which is part of Public Health England, UK.

PO Box 270 Brenda Road, Hartlepool TS25 2BW UKExwold is a contract chemical processing company. We are based in the UK and have decades of experience formulating and processing speciality chemicals for multi-national chemical and agrochemical companies. If you are a producer of speciality chemicals Exwold can offer you a bespoke outsourcing solution to process them. We work in many different sectors of the industry and have specialist knowledge in the following areas: flame retardants, agrochemicals, biocides, herbicides and animal feed additives.

Unit 12, Low March Industrial Estate Daventry, Northamptonshire NN11 4SD United KingdomEndeavour Speciality Chemicals specializes in organic intermediates and offers custom synthesis and manufacturing services.

45 Roman Way Longridge Road Ribbleton Preston Lancashire England PR2 5BDEuropean Freeze Dry is a market leading producer of freeze dried products and provider of speciality freeze drying services to a diverse range of industries. 2014 will be the 50th anniversary of us freeze drying and supplying freeze dried products, resulting in a wealth of knowledge, experience and industry expertise. Our product capabilities are extensive and we are continually investigating and developing new freeze drying applications. We specialise in supplying a considerable range of Food Ingredients and additionally offer modified atmosphere packing, milling, blending and sieving options. We pride ourselves in providing quality freeze dried ingredients and bespoke flexible solutions for the food manufacturing industry. In addition we also offer a Contract Drying facility where we support a portfolio of clients in freeze drying their products. This customer base ranges from large food suppliers and manufacturers, through to speciality chemical, nutraceutical and biological processors. We also work on document recovery in support of emergency and disaster recovery operations. At European Freeze Dry we offer the service to design, manufacture and package Customer Ready Products. Working from the customer’s brief we are able to offer tailored solutions to meet even the most demanding of standards. Using our onsite cooking facilities our development team can create a complete concept, such as a meal, which meets target nutritional requirements whether this is for sports recovery, weight loss, convalescence or a child friendly snack. Due to the fact that we cook and then freeze dry products we are able to offer ingredients declarations have no requirements for artificial colours or flavours.

1 Roxburgh Street Edinburgh, Scotland, EH8 9TA United Kingdom

Discovery Building, Biocity Pennyfoot Street Nottingham, NG1 1GF United KingdomExcellerate Bioscience is a dynamic and innovative contract research organization built on a worldwide reputation for excellence in the field of molecular and cellular pharmacology. Working from our new headquarters in BioCity, Nottingham UK, we are an experienced team of creative and collaborative drug discovery scientists that provide in-vitro pharmacology solutions to some of world’s leading pharmaceutical, biotechnology and academic institutes. Our aim is to combine the best of academic and industrial science to develop innovative approaches that will improve the efficiency and translatability of in vitro pharmacological profiling.

Rowland Hill Street England, NW3 United KingdomEngitix is the first biotech in the world applying human extracellular matrix (ECM) biomaterials for drug discovery and development in fibrosis and solid tumours. The ECM is the non-cellular component present within all tissues and organs and provides not only essential physical scaffolding for the cellular constituents but also initiates crucial biochemical and biomechanical cues that are required for tissue morphogenesis, differentiation and homeostasis. However, dysregulated ECM remodelling is associated with pathological conditions and can exacerbate disease progression such as fibrosis and cancer. The loss of tissue ECM homeostasis and integrity is seen as one of the hallmarks of cancer and typically defines transitional events in cancer progression and metastasis. Consequently, ECM molecules and/or mechanisms associated to ECM remodelling are important targets for pharmacotherapy. Unfortunately, until recently, ECM has been largely ignored in drug discovery. The rapidly increasing knowledge in the biology of the ECM will likely lead to compounds able to directly target the ECM with significant advantages in the treatment of chronic fibrogenic human and oncology diseases.

Rowland Hill street United Kingdom London, London, City of, NW3 2PF United KingdomEngitix is the first biotech in the world applying human extracellular matrix (ECM) biomaterials for drug discovery and development in fibrosis and solid tumours. The ECM is the non-cellular component present within all tissues and organs and provides not only essential physical scaffolding for the cellular constituents but also initiates crucial biochemical and biomechanical cues that are required for tissue morphogenesis, differentiation and homeostasis. However, dysregulated ECM remodelling is associated with pathological conditions and can exacerbate disease progression such as fibrosis and cancer. The loss of tissue ECM homeostasis and integrity is seen as one of the hallmarks of cancer and typically defines transitional events in cancer progression and metastasis. Consequently, ECM molecules and/or mechanisms associated to ECM remodelling are important targets for pharmacotherapy. Unfortunately, until recently, ECM has been largely ignored in drug discovery. The rapidly increasing knowledge in the biology of the ECM will likely lead to compounds able to directly target the ECM with significant advantages in the treatment of chronic fibrogenic human and oncology diseases.

Babraham, England, CB22 3AU United KingdomEagle Genomics specializes in bioinformatics and offers data mining, next generation sequencing data analysis, microarray analysis, and other applications.

Babraham Hall Babraham Research Campus\ Babraham, Cambridge CB22 3AT United KingdomEagle Genomics specializes in bioinformatics and offers data mining, next generation sequencing data analysis, microarray analysis, and other applications.

15 Brackenbridge Drive, South Ruislip London, HA4 0NF United KingdomHealthcare technology company building tools to drive better decision making in healthcare. We specialise in consulting and technology for pharmaceutical clients in the area of health economics and outcomes research with a particular focus on network meta analysis.

90 Park Drive Milton Park Milton, England, OX14 4RY United KingdomEurofins Discovery has supported Drug Discovery research for >40 years. We offer a complete, single-source solution for drug discovery products and services and are rooted in the deep expertise and best-in-class offerings of 6 premier CROs: Cerep, DiscoverX, EMP Millipore Drug Discovery Solutions, Panlabs, Selcia Drug Discovery, and Villapharma. Eurofins Discovery can optimize your process - whether you need complete, end-to-end services, help with one or more stages, or the products for discovery work. The Eurofins Discovery team was built by bringing together the market-leading discovery expertise of Panlabs (acquired in 2012 from Ricerca), Cerep (acquired in 2013), EMD Millipore's Discovery & Development Solutions business (acquired from Merck KGaA in 2014), Villapharma Research (acquired in 2017), DiscoverX (acquired 2017), and Selcia Drug Discovery (acquired 2018). With over 600 people in seven operational sites worldwide: St. Charles, MO (USA), Fremont, CA (USA), San Diego, CA (USA), Essex (UK), Celle Lévescault (France), Taipei (Taiwan), and Murcia (Spain) our global team offers the high quality, reliable solutions and support our clients depend on to advance their drug discovery programs Combining our broad, high quality, industry-leading drug discovery products & services portfolios together enables us to support our global clients with one of the industry’s largest and broadest portfolios.

Metro Building 6th Floor, 1 Butterwick London, W6 8DL United KingdomEvidera was formed in 2013 when Symphony Technology Group (STG), a private equity firm focused on technology and services, acquired the health economics (HE), outcomes research (OR), market access, epidemiology and data analytics practices of United BioSource Corporation (UBC), a wholly owned subsidiary of Express Scripts Holding Company. Evidera has over 30 year of leadership and experience and its legacy brands include MEDTAP, Caro Research, Abt Bio-Pharmaceutical Solutions, MetaWorks, Total Healthcare Group and Archimedes. Evidera’s 300 researchers and consultants have expertise working in all developed and many developing countries. U.S. headquarters in Bethesda, MD (Washington, D.C.) European headquarters in London Primary offices in Boston, Budapest, Harrisburg, Montreal, San Francisco and Seattle

201 Talgarth Rd Hammersmith, London, W6 8BJ United KingdomEvidera was formed in 2013 when Symphony Technology Group (STG), a private equity firm focused on technology and services, acquired the health economics (HE), outcomes research (OR), market access, epidemiology and data analytics practices of United BioSource Corporation (UBC), a wholly owned subsidiary of Express Scripts Holding Company. Evidera has over 30 year of leadership and experience and its legacy brands include MEDTAP, Caro Research, Abt Bio-Pharmaceutical Solutions, MetaWorks, Total Healthcare Group and Archimedes. Evidera’s 300 researchers and consultants have expertise working in all developed and many developing countries. U.S. headquarters in Bethesda, MD (Washington, D.C.) European headquarters in London Primary offices in Boston, Budapest, Harrisburg, Montreal, San Francisco and Seattle

Bessemer Drive Business and Technology Centre, Stevenage, SG1 2DX United KingdomeMolecules is an eCommerce company that supplies samples to customers all over the world with a strong background in cheminformatics.

Citylabs 1.0 Nelson Street Manchester, M13 9NQ United KingdomEx5 Genomics is a novel start-up company, though we were established in 2019 we have been operating as a genomics company since 2000 as part of Tepnel, Gen-Probe and Hologic. We have built significant expertise and experience in genomics over the last 19 years and have spun out of Hologic with staff that collectively have >100 years experience workings for a genomics projects for our customers that range from global top 10 pharma, through small biotech to academic and research institutions. We have recently been purchased by and are now a YourGene-Health company. As part of their international molecular diagnostics group which develops and commercialises genetic products and services. The group works in partnership with global leaders in DNA technology to advance diagnostic science. Our product development, research service and commercial capabilities extend across the lifecycle of DNA test development including regulatory submissions.

61 Pencroft Way Manchester Science Park England, M15 6AY United KingdomEx5 Genomics is a novel start-up company, though we were established in 2019 we have been operating as a genomics company since 2000 as part of Tepnel, Gen-Probe and Hologic. We have built significant expertise and experience in genomics over the last 19 years and have spun out of Hologic with staff that collectively have >100 years experience workings for a genomics projects for our customers that range from global top 10 pharma, through small biotech to academic and research institutions. We have recently been purchased by and are now a YourGene-Health company. As part of their international molecular diagnostics group which develops and commercialises genetic products and services. The group works in partnership with global leaders in DNA technology to advance diagnostic science. Our product development, research service and commercial capabilities extend across the lifecycle of DNA test development including regulatory submissions.

Charwell House Cheddar Business Park Wedmore Road Cheddar, Somerset BS27 3EB United KingdomEnvironmental Water Systems offers a complete range from ultra pure fully validated turnkey packages, standard water treatment and water purification plant, effluent treatment and wastewater recovery, laboratory water purifiers plus associated spares and consumables.

Cheddar, England, BS27 United KingdomEnvironmental Water Systems offers a complete range from ultra pure fully validated turnkey packages, standard water treatment and water purification plant, effluent treatment and wastewater recovery, laboratory water purifiers plus associated spares and consumables.

Edinburgh, UKWelcome to the website for the MRC Brain and Tissue Banks in Edinburgh. The purpose of these three Banks is to collect donated samples from the brain and other organs of the body during post mortem examination, and to make these available for medical research. All the samples stored in the Edinburgh Banks are fully authorised for research by families and ethically approved for research use in accordance with the terms of current UK Human Tissue legislation. During the last 100 years or so, much of our knowledge of brain disorders has come from the study of post mortem tissues, based on identifying the differences between diseased and control (normal) brains. Advances in the diagnosis and treatment, as well as understanding the genetic background, of disorders such as Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease and the effects of head injury have all depended on research using Brain Bank resources in different countries.

John Eccles House Robert Robinson Avenue The Oxford Science Park Oxford, OX4 4GP United KingdomEnzyme Supplies provides a comprehensive range of enzymatic & biological solutions to support industrial/retail waste, pharmaceutical, nutraceutical, and agricultural applications.

New Road East Malling Kent ME19 6BJEast Malling Research (EMR), located in Kent, England, has a history dating back to 1913 when it was established by the fruit growing sector to address the many challenges faced by growers. Since its establishment, the team at East Malling have introduced wide-ranging advances to horticulture which have shaped the way produce is grown and supplied to the consumer. Today, our mission is to conduct high-quality strategic and applied research in horticultural and environmental sciences, and to deliver knowledge, products and services that benefit public and private customers. Our vision is to be recognised as the pre-eminent research institute in the UK, with a significant international reputation for strategic and applied research, development and innovation in horticulture, with particular emphasis on perennial and clonally propagated crops.

New Road East Malling, England United KingdomEast Malling Research (EMR), located in Kent, England, has a history dating back to 1913 when it was established by the fruit growing sector to address the many challenges faced by growers. Since its establishment, the team at East Malling have introduced wide-ranging advances to horticulture which have shaped the way produce is grown and supplied to the consumer. Today, our mission is to conduct high-quality strategic and applied research in horticultural and environmental sciences, and to deliver knowledge, products and services that benefit public and private customers. Our vision is to be recognised as the pre-eminent research institute in the UK, with a significant international reputation for strategic and applied research, development and innovation in horticulture, with particular emphasis on perennial and clonally propagated crops.

3, Crossfield Close Shinfield Reading RG2 9AY, United KingdomEurofins EAG Materials Science, LLC has a long history, dating back to the birth of the company in 1978 in California, as Charles Evans & Associates. Over the years we have expanded from a single location offering SIMS only to having over 200 employees offering over 30 different services via 14 locations in 8 different countries. The original focus of the company was supporting semiconductor manufacturing but now we also work with multiple further industries beyond semiconductors, including: solar/PV, lighting, photonics, energy storage, aerospace & defense, medical devices, raw materials, glass, polymers and plastics and consumer products. EAG's analytical expertise is what enables us to help our clients to meet their goals. Our on-demand analytical testing services can help streamline R&D, solve urgent problems during manufacturing and help resolve materials related issues in the global supply chain, both within and between organizations.

Scotland, EH26 0PZ United Kingdom

Glencorse Building Pentlands Science Park Bush Loan Penicuik Midlothian Scotland EH26 0PZ UK

National Biomanufacturing Centre Estuary Banks Estuary Commerce Park Speke Road, Liverpool, UK L24 8RBEden Biodesign provides expression system development, process development, cGMP manufacturing, quality control, and analytical services.

Units 1-4 Craven Court Camberley Surrey GU15 3BW UKExova provides environmental testing, pharmaceutical testing, immunoassay development, formulation, characterization, and batch release testing.

IPC 600, Discovery Park House, Discovery Park, Ramsgate Road, Sandwich, Kent, CT13 9NJ United KingdomEligoChem designs, synthesises and markets compound libraries with good drug properties that access novel chemical space for use in Drug Discovery screening. EligoChem also provides library design and synthesis services to enable lead development into novel chemical space. EligoChem utilises a proprietary, unique and innovative approach to compound design to improve success rates in Drug Discovery.

18 Springfield Park, Tisbury, Salisbury, Wiltshire UK SP3 6QNEGG Tech provides embryo transfer, cell culture products, sera, and chick embryo extract.

Salisbury, England United KingdomEGG Tech provides embryo transfer, cell culture products, sera, and chick embryo extract.

Bude-Stratton Business Park Bude Cornwall EX23 8LY UKExelgen provides drug discovery chemistry services.

Newton Hall, Town Street Newton, Cambridge CB22 7ZE United KingdomEnzagen has over 20 years of experience in industrial biocatalysis, covering all aspects of manufacturing processes using enzymes.

Summer Road, Thames Ditton, Surrey KT7 0RH, EnglandExpo Technologies provides consultancy, engineering solutions, on-site services and training programs.

2nd Floor The Port House, Marina Keep, Port Solent, Hampshire, PO6 4TH.ɛstimand was founded by Dr Gianluca Campanella in 2015. Dr Campanella is currently a post-doctoral research fellow in the Department of Epidemiology and Biostatistics at Imperial College London. He is also part of the MRC-PHE Centre for Environment and Health.

Fyfield Business & Research Park Fyfield Road Ongar, Essex, CM5 0GS United KingdomEurofins Integrated Discovery UK Ltd is a leading provider of contract research services in drug discovery to the pharmaceutical and biotechnology industries as well as academic institutions, charities and not-for-profit organisations. Eurofins Integrated Discovery exclusively offer a Peptidyl-Prolyl-Isomerase (cyclophilin, FKBP and pin1) Profiling Portfolio that includes both binding and functional assays. In addition we offer cell-based assays to assess mitochondrial function and death, and cell-based models for Parkinson’s disease. We specifically provide expertise, resource and project management of integrated drug discovery services, including medicinal and synthetic chemistry, biology and ADME, as required to accelerate early drug discovery customer projects and deliver preclinical drug candidates. The highly industry experienced Eurofins Integrated Discovery team has a 100% track record of delivering preclinical candidates for our customers, with a number entering the clinic most recently. In addition, Eurofins Integrated Discovery scientists provide innovative solutions to customer drug discovery projects as proven by their co-authorship on >100 patents and publications. Furthermore, Eurofins Integrated Discovery assists academic groups and biotechnology companies with scientific expertise to support grant applications; to date Eurofins Integrated Discovery has helped such groups to receive a total of over $10 million funding to initiate and advance their drug discovery projects

Babraham Hall Babraham Cambridge Cambridgeshire CB22 3AT UNITED KINGDOMExpedeon Ltd provides protein folding, analytics, purification, stabilization, and scale-up.

The Lenz Hornbeam Business Park Harrogate HG2 8RE UKWith over 90 scientific and engineering disciplines, Exponent’s staff of approximately 900, located in 20 offices throughout the United States and 5 international offices, combines unparalleled technical expertise with the ability, when necessary, to focus this knowledge in extremely short time frames. Our multidisciplinary team of scientists, physicians, engineers, and regulatory consultants will perform either in-depth scientific research and analysis, or very rapid-response evaluations, to provide our clients with the critical information that both day-to-day and strategic decisions can require. Exponent is certified to ISO 9001.

48 Grafton Street Manchester, M13 9XX United KingdomEpistem provides innovative preclinical models for efficacy testing in oncology, skin (in vitro and in vivo models), wound healing, auto-immune and inflammatory diseases (IBD and RA). Epistem also offers organoid models for toxicity testing in four different species. Epistem also provides contract sample analysis using a range of techniques. We offer GCLP compliant pharmacogenomic services (RNA gene expression (mRNA and miRNA) and DNA Genotyping profiling services) using NGS (Illumina), microarray (Affymetrix) and qPCR assessments as the final readouts. We also offer GCLP compliant histology and IHC services and have extensive experience in optimizing assays and then routinely deploying them to assess preclinical and clinical samples. We also offer other techniques including laser capture microdissection (LCM), FACS analysis and protein detection services (single and multiplexed assays). We have also optimized the use of plucked scalp hair as a surrogate tissue to monitor drug response in clinical settings and have preclinical models we use to define a biomarker strategy for subsequent use in clinical settings.

EPP Environmental Centre Bush Estate Penicuik Scotland EH26 0PH UKWhy choose EPP We are time and cost conscious and our practical tailored approach ensures we are well priced. Outcomes are important to everyone and developing long term partnerships with customers enables us to repeatedly deliver and bring cost effectiveness. Aim and Vision At EPP we aim to enlighten each customer, providing greater knowledge and understanding to accelerate and enable successful outcomes. We deliver this aim by providing integrated and specialist analytical and development services, of consistently superior quality, founded upon our expert competencies in screening and synthesis, analytical services and environmental science. Our innovative approach and unequalled performance confirms our position as a trusted, reliable partner and the CRO of choice.

Glencorse Building Pentlands Science Park Bush Loan Penicuik Midlothian Scotland EH26 0PZ UKWhy choose EPP We are time and cost conscious and our practical tailored approach ensures we are well priced. Outcomes are important to everyone and developing long term partnerships with customers enables us to repeatedly deliver and bring cost effectiveness. Aim and Vision At EPP we aim to enlighten each customer, providing greater knowledge and understanding to accelerate and enable successful outcomes. We deliver this aim by providing integrated and specialist analytical and development services, of consistently superior quality, founded upon our expert competencies in screening and synthesis, analytical services and environmental science. Our innovative approach and unequalled performance confirms our position as a trusted, reliable partner and the CRO of choice.

London, UKThe ERA Consulting Group provides biopharmaceutical consulting relating to quality, nonclinical, and clinical aspects.

2 Royal College Street, Camden London NW1 0NH - UKThe ETT - ‘ALTERNATIVE TOXICITY SERVICES’ platform provides a high content screening services for evidence based acute general toxicity and neurotoxicity, taking advantage of alternative test methods in compliance with the international principles of the 3Rs - Replacement, Refinement and Reduction.

10 Albemarle Street, London, W1S 4HH, United KingdomElementis Specialties provides high value functional additives to many markets including architectural and industrial coatings, personal care and oilfield drilling. These additives improve the flow characteristics and performance of our customers’ products or production processes. We offer a comprehensive product portfolio that includes rheology modifiers for aqueous and solvent systems, defoamers, colorants, waxes, dispersing and wetting agents, adhesion promoters and surface active additives.

40 Occam Road, The Surrey Research Park, Guilford, Surrey, GU2 7YG, UKEuropean Centre for Chirality (EC2), through the partnership of the BioTools Inc, University of Antwerp and Ghent University, offers chiral related analytical services to support structure determination.

3 Bishop Square Hatfield, AL10 9NA United KingdomeBioscience offers custom antibody conjugation services, antibody and recombinant protein products, and detection kits.

Parkshot House, 5 Kew Road Richmond, Surrey TW9 2PR United KingdomEmergent is dedicated to one simple mission—to protect and enhance life. As a global specialty pharmaceutical company, Emergent offers specialized products to healthcare providers and governments to address medical needs and emerging health threats. Our goal We pursue innovative ways to protect life. Whether it is developing and delivering specialized products that can make life better for millions of adults and children or medical countermeasures that protect the nation against chemical and biological threats, we are passionate in pursuit of our mission—to protect and enhance 50 million lives by 2025. We give highest priority to:​ • Delivering on our commitments to patients, customers and partners • Pursuing innovation in our product portfolio • Developing our employees • Giving back to our communities • Achieving our financial goals

Livingston, Scotland United KingdomEncap Drug Delivery is focused on using its liquid and semi solid fill technology to support formulation development and clinical manufacturing.

Monks Heath Hall , Chelford Road, Nether Alderley, Cheshire, SK10 4SY, UKFluidX provides sample storage consumables, barcode reading, sealing, and liquid handling.

7300 Cambridge Research Park Cambridge, CB25 9TN United KingdomFahy Gurteen Laboratories develops nucleic acid tests and high throughput systems for fully automated immunohistochemistry and immunocytochemistry staining of tumour tissues and cytospin preparation.

7300 Cambridge Research Park Cambridge, CB25 9TN United KingdomFahy Gurteen Laboratories develops nucleic acid tests and high throughput systems for fully automated immunohistochemistry and immunocytochemistry staining of tumour tissues and cytospin preparation.

7300 Cambridge Research Park Beach Drive Waterbeach, Cambridge, Cambridgeshire, CB25 9TN United KingdomFahy Gurteen Laboratories develops nucleic acid tests and high throughput systems for fully automated immunohistochemistry and immunocytochemistry staining of tumour tissues and cytospin preparation.

Unit 1, Pale Lane Farm Hartley Wintney, Hampshire, RG27 8DH United KingdomFleet Bioprocessing Ltd. is a CRO with specialist skills in the development of immunoassays, and in the development and manufacture of labelled antibodies and other bioconjugates for use in immunoassays and many other applications. Our main customer sectors for these products are clinical diagnostics (for human IVD use) and pharma (for PK, PD, ADA assays etc).

RG27 8DH United KingdomFleet Bioprocessing Ltd. is a CRO with specialist skills in the development of immunoassays, and in the development and manufacture of labelled antibodies and other bioconjugates for use in immunoassays and many other applications. Our main customer sectors for these products are clinical diagnostics (for human IVD use) and pharma (for PK, PD, ADA assays etc).

3 COLLEGE YARD LOWER DAGNALL STREET St Albans, Hertfordshire, AL3 4PA United KingdomWe are a consultancy committed to launching products that make a difference in people’s lives. We work across a product’s lifecycle, supporting biotech, pharmaceutical, and medical technology companies across the globe. Our 5 key services and two products include: Outcomes Research Our team provide unequalled accuracy and quality whilst delivering all aspects of systematic reviews, meta-analyses and patient-level data analyses. Economic Modelling We develop a range of robust health economic models that meet the commercial needs of our clients from simple Markov models to complex discrete event simulations. Health Technology Assessment We have extensive experience delivering successful HTA submissions in the UK and across the globe. Value Communication We effectively communicate the value of your products in a logical and insightful manner; from internal value dossiers to external scientific publications. Pricing & Reimbursement We partner with our clients to develop strategies for global pricing and reimbursement, harnessing our extensive KOL and payer network. FIECON challenge the conventional and think outside the box to provide game-changing, innovative products that meet your commercial needs. FIECON Model Builder can help you build best-in-class Excel-based cost-effectiveness models, whilst significantly reducing building time. Our online platform automates the design and development process of cost-effectiveness models, removing the risk of human error and guaranteeing accuracy. Ratified, endorsed, and used by key payers and HTA agencies, models can be built in a matter of minutes rather than weeks. FIECON Value Platform can help you manage and optimise your product’s pricing and market access processes. Your online portal helps Global teams quickly understand progress, priorities, and support needs in local markets, saving you time, increasing team efficiency, and ensuring unity and alignment.

2nd Floor, 6 Arlington St London, SW1A 1REFreenome (free•nohm) is the dynamic collection of genetic material floating in your blood (cell-free) derived from the trillions of cells in your body. It is your living cell-free genome changing over time and space. Your freenome is the genomic thermometer of who you are as you grow, live, and age. Our platform allows you to track the health of your freenome so you can make the best decisions for you. Your freenome helps you design your “healthy" and then serves as a warning system for “unhealthy" conditions such as cancer so that you can get the care that you need, when you need it. It is precision wellness - for your freenome - for your health.

Fios Genomics BioCube 1, 13 Little France Road Edinburgh, Scotland, EH16 4UX United KingdomFios Genomics has nearly 15 years of experience in supporting scientists, researchers and bioinformaticians in all areas of data analysis. Our team have extensive experience in handling all types of datasets for human pharmaceutical development, diagnostics, agricultural research, veterinary medicine and applied research across all species. In drug development, we work from the target identification stage through to analysis of multi-modality late-stage clinical trials integrating all the data types collected to ensure robust conclusions and data-driven decision making. Our team can help overcome challenges in use and integration of ‘omics technologies; namely microarrays, NGS, proteomics, metabolomics & metagenomics, and the integration of data from non-omics technologies. Using a combined in-house resource of bioinformaticians, computational biologists and statisticians we can help you get more information from the ‘omic experiments you currently perform or help you integrate these technologies into your development pipelines. We specialise in the biological interpretation and pathway analysis of high dimension, high variance datasets to aid biomarker ID, predictive toxicology, genotyping, proof of concept, biosimilar/bioequivalence studies, patient stratification, repurposing strategies and biological production process development/improvement for pharmaceutical companies, CMOs and research institutions. Our experience ranges from biomarker discovery to large phase III clinical trial data analysis. We work with clients worldwide to deliver information rather than simply more data. More information is available on our website (www.fiosgenomics.com).

Nine Edinburgh Bioquarter, 9 Little France Road Edinburgh, EH16 4UX United KingdomFios Genomics has nearly 15 years of experience in supporting scientists, researchers and bioinformaticians in all areas of data analysis. Our team have extensive experience in handling all types of datasets for human pharmaceutical development, diagnostics, agricultural research, veterinary medicine and applied research across all species. In drug development, we work from the target identification stage through to analysis of multi-modality late-stage clinical trials integrating all the data types collected to ensure robust conclusions and data-driven decision making. Our team can help overcome challenges in use and integration of ‘omics technologies; namely microarrays, NGS, proteomics, metabolomics & metagenomics, and the integration of data from non-omics technologies. Using a combined in-house resource of bioinformaticians, computational biologists and statisticians we can help you get more information from the ‘omic experiments you currently perform or help you integrate these technologies into your development pipelines. We specialise in the biological interpretation and pathway analysis of high dimension, high variance datasets to aid biomarker ID, predictive toxicology, genotyping, proof of concept, biosimilar/bioequivalence studies, patient stratification, repurposing strategies and biological production process development/improvement for pharmaceutical companies, CMOs and research institutions. Our experience ranges from biomarker discovery to large phase III clinical trial data analysis. We work with clients worldwide to deliver information rather than simply more data. More information is available on our website (www.fiosgenomics.com).

Suite 8525, 16-18 Circus Road St. John's Wood London, United KingdomFinetech Industry specializes in developing, manufacturing and marketing fine organic compounds and intermediates for the pharmaceutical industry.

Stockton-on-Tees, England, TS2 United KingdomFine Contract Research focuses on route scouting, pR&D (including design of experiments for optimisation and critical parameter studies) and manufacture with the goal of supporting the API innovators (Universities, virtual to Large Pharma, Biotech), Agrochemical and speciality/effects chemical sectors. In addition to the above we can support activities as diverse as hazard evaluation (DSC,ARC,RC-1,Carius tube), reference standard, impurity, and metabolite syntheses as well as stable isotope labelling.

Suite 6 The Brew Tower Marlow Bucks SL7 2UQ UKWe have been providing competitive intelligence for our clients since 1988—before Google, before e-mail, before LinkedIn. While we have grown and adapted as the world has changed and use everything we can to get the job done ethically, we also know that the new technologies can easily become crutches, and many users never scratch below the surface of search results.

England United KingdomAt the heart of FieldArm there are five agronomists holding BASIS, FACTS and NPTC qualifications, together with trained support staff, who have many years of agricultural and trials expertise between them. Since our inception in early 2009, we have conducted over 800 trials (400 in the last two years) mostly in the UK for many of the multi-national agrochemical companies, farming groups and distributors.

Legh Coach House Wimslow Rd Mottram-St Andrew Cheshire sk10 4QH UKFulhold provides APIs, in vitro efficacy studies, and research for human and veterinary studies.

PO Box 1, Lankro Way, Eccles Manchester, M30 0BH U.K.F2G provides MIC testing, high throughput screening, bioinformatics, analytical services, and antifungal research.

60 Fitton Rd, King's Lynn PE34 3AX, United KingdomF.T. Short are contract packing specialists. We are constantly investing in our machinery, facilities and people to improve our service. We make it a matter of pride to ensure the delivery of fast, effective solutions. We are set up to deal with any of your contract packing or reworking requirements.

Sanderum House Oakley Road Chinnor OX39 4TW United KingdomFinVector is a world leader in the research and development of Viral-Based Gene Therapy products. Our state-of-the-art facilities, highly experienced scientific team and commitment to work closely with clients every step of the way, have helped us to build an excellent reputation in the gene therapy market. We are authorised under EMA for the production of gene therapy products for clinical and commercial supply. We offer services across a wide range of viral-based product types, including Adenoviral, AAV, and Lentiviral-based vectors. From our cutting-edge fully-licensed GMP manufacturing facility in Finland, we have built an extensive pipeline of gene therapy products and technologies for our clients.

Oakley Road OX39 4TW United KingdomFinVector is a world leader in the research and development of Viral-Based Gene Therapy products. Our state-of-the-art facilities, highly experienced scientific team and commitment to work closely with clients every step of the way, have helped us to build an excellent reputation in the gene therapy market. We are authorised under EMA for the production of gene therapy products for clinical and commercial supply. We offer services across a wide range of viral-based product types, including Adenoviral, AAV, and Lentiviral-based vectors. From our cutting-edge fully-licensed GMP manufacturing facility in Finland, we have built an extensive pipeline of gene therapy products and technologies for our clients.

National Agri-Food Innovation Campus, Sand Hutton, York, YO41 1LZ, United KingdomOur vision is to be a leading supplier of scientific solutions, evidence and advice across the agri-food supply chain. Our role is about understanding problems and enabling sustainable solutions through innovative thinking and the gathering and analysis of robust scientific evidence. This gives us the right platform to be able to support our customers in both the strategic and day-to-day decisions they face. By listening to what our customers tell us, it is clear that our ability to understand a problem and find solutions is what differentiates Fera. In some cases this involves working as multidisciplinary teams within Fera, and in others we are tapping into the extensive worldwide network of partnerships we have created with other research organisations and academia.

117 Avalon Gardens Scotland, EH49 7PL United KingdomBased near Edinburgh in Scotland, UK, ForthTox Ltd is a dynamic and proactive consultancy firm, with a broad range of toxicological expertise in: Pharmaceutical development Medical device development Chemicals (REACH) In Silico Toxicology Including ICH M7 compliant assessments General toxicological consultancy Legal toxicology Occupational toxicology Training in toxicology and CPD Founded in 2001, and incorporated in 2003 as APAHW Consulting Ltd, by Adam Woolley, a toxicologist of 30 years standing. ForthTox seeks to build on the broad experience of its principle consultants to provide elegant and cost effective solutions to customer projects or problems in toxicology. ForthTox is an independent, toxicological consultancy working in pharmaceutical and chemical development; we are located in Scotland. We offer two proprietary in silico models for prediction of toxicity: Leadscope and Derek Nexus and use other software, such as T.E.S.T., CAESAR and ToxTree as appropriate; we also have a licence for METEOR for prediction of metabolism, allowing cross-checking of metabolites for toxicity. The results of in silico evaluation are validated, where appropriate, by reference to reports for closely related substances or by read across to groups of related chemicals, depending on context and information availability. We have extensive experience with in silico and in cerebro evaluations and our reports have been submitted to, and accepted by, major authorities including FDA and EMA.

Belasis Avenue Billingham, TS23 1LH United KingdomFujifilm Diosynth provides third party Contract Analytical, Development and Manufacturing services to the biopharmaceutical industry, offering a proven track record in process development and cGMP manufacturing of cell culture and microbially expressed proteins.

Frontier Science (Scotland) Ltd Grampian View Kingussie, Kingussie, PH21 1NA United KingdomFrontier Science (Scotland) Ltd is a not-for-profit contract research organisation. We provide expertise in the design, conduct and analysis of clinical trials. Specialising in data management and statistical support, we tailor solutions to deliver excellence in clinical research.

Frontier Science (Scotland) Ltd Grampian View Kingussie, Kingussie, PH21 1NA United KingdomFrontier Science (Scotland) Ltd is a not-for-profit contract research organisation. We provide expertise in the design, conduct and analysis of clinical trials. Specialising in data management and statistical support, we tailor solutions to deliver excellence in clinical research.

Seal Sands Middlesbrough TS2 1UBFine Organics Limited offers chemical analysis and scale up services.

Middlesbrough, England United KingdomFine Organics Limited offers chemical analysis and scale up services.

Unit A The Paddocks Business Centre Cherry Hinton Road Cambridge, Cambridgeshire, CB1 8DH United KingdomFluidic Analytics – Understand the Machinery of Life Fluidic Analytics envisions a world where information about proteins and their behaviour transforms our understanding of how the biological world operates, and helps all of us make better decisions about how we diagnose diseases, develop treatments and maintain our personal well-being. By building the world’s best tools, software and services for protein characterisation and making them universally accessible in the lab, in the clinic or at home, we are making this vision a reality not just for a small group of expert users, but for everyone who can benefit. www.fluidic.com

Cherry Hinton Road Cherry Hinton Road England, CB1 8DH United KingdomFluidic Analytics – Understand the Machinery of Life Fluidic Analytics envisions a world where information about proteins and their behaviour transforms our understanding of how the biological world operates, and helps all of us make better decisions about how we diagnose diseases, develop treatments and maintain our personal well-being. By building the world’s best tools, software and services for protein characterisation and making them universally accessible in the lab, in the clinic or at home, we are making this vision a reality not just for a small group of expert users, but for everyone who can benefit. www.fluidic.com

Sanderum House Oakley Road Chinnor, Oxon OX39 4TW, United KingdomFlavorActiV is dedicated to providing Sensory Taster Management, Taster Validation and Sensory Training to customers worldwide with our team of multilingual Global Sensory Managers. FlavorActiV is the world’s only provider of pharmaceutical quality produced and controlled GMP Flavour Standards for use in beer, wine, cider, carbonated soft drinks, waters and many other beverages to help train professional sensory panels.

38 Oakley Road England, OX39 4TW United KingdomFlavorActiV is dedicated to providing Sensory Taster Management, Taster Validation and Sensory Training to customers worldwide with our team of multilingual Global Sensory Managers. FlavorActiV is the world’s only provider of pharmaceutical quality produced and controlled GMP Flavour Standards for use in beer, wine, cider, carbonated soft drinks, waters and many other beverages to help train professional sensory panels.

Derbyshire, UKFluorochem offers a chemistry catalog consisting of fluorochemicals, silanes, nmr solvents and accessories, inorganics, silica gel and organic intermediates.

The National Agri-Food Innovation Campus, Sand Hutton, York, YO41 1LZOur role is about understanding problems and enabling sustainable solutions through innovative thinking and the gathering and analysis of robust scientific evidence. This gives us the right platform to be able to support our customers in both the strategic and day-to-day decisions they face. By listening to what our customers tell us, it is clear that our ability to understand a problem and find solutions is what differentiates Fera. In some cases this involves working as multidisciplinary teams within the Agency, and in others we are tapping into the extensive worldwide network of partnerships we have created with other research organisations and academia.

The National Agri-Food Innovation Campus, Sand Hutton, York, YO41 1LZOur role is about understanding problems and enabling sustainable solutions through innovative thinking and the gathering and analysis of robust scientific evidence. This gives us the right platform to be able to support our customers in both the strategic and day-to-day decisions they face. By listening to what our customers tell us, it is clear that our ability to understand a problem and find solutions is what differentiates Fera. In some cases this involves working as multidisciplinary teams within the Agency, and in others we are tapping into the extensive worldwide network of partnerships we have created with other research organisations and academia.

National Agri-food Innovation Campus Sand Hutton, York, YO41 1LZ United KingdomOur role is about understanding problems and enabling sustainable solutions through innovative thinking and the gathering and analysis of robust scientific evidence. This gives us the right platform to be able to support our customers in both the strategic and day-to-day decisions they face. By listening to what our customers tell us, it is clear that our ability to understand a problem and find solutions is what differentiates Fera. In some cases this involves working as multidisciplinary teams within the Agency, and in others we are tapping into the extensive worldwide network of partnerships we have created with other research organisations and academia.

Suite 40, Pure Offices Brooks Drive, Cheadle Royal Business Park Cheadle, Greater Manchester, SK8 3TD United KingdomOur team of experts can help you to build your market access, pricing and launch strategies to maximise your commercial opportunity. As your strategic partner, we will help you to manage expectations internally and achieve the best possible outcomes at launch via strategic guidance and targeted payer insights . We have spent 5 years selecting and recruiting the best Market Access experts and consultants from around the world. From our industry-leading Senior Directors through to our seasoned consulting team and network of in-market experts; each individual brings their unique experience in the pharmaceutical sector to drive realistic and achievable launch strategies.

Pure Offices, Wilton Drive Warwick, CV34 6RG United KingdomForenteQ Limited located in Warwick is the UK stockist and distributor for the microGEM range of temperature driven DNA and RNA extraction kits. Highly effective for a wide range of animal, plant, human DNA and RNA extraction.

1 Springbank Road Belfast, BT17 0QL United KingdomFusion Antibodies is a contract research organisation, which designs, and optimizes therapeutic antibodies for the healthcare market. We help clients solve complex, challenging problems throughout their early discovery antibody programs. Our expertise is defined by our experience. Unique process frameworks, and technology platforms, enable our clients to develop therapeutics within the most challenging modalities and diseases. Guiding clients through early-stage antibody discovery, in the most efficient and effective way, we enable biotechnology and pharmaceutical organizations towards their end-goal – the provision of treatments that improve the lives of patients worldwide. As an independent team, we offer flexibility and agility that antibody discovery and development programs require. Our approach to projects considers long-term impacts on safety, efficacy, and manufacturability at every stage, de-risking antibody programs and maximizing success. As an early discovery partner, our scientists increase the pace to the clinic by guiding clients to develop the best antibodies possible.

Springbank Industrial Estate, Pembroke Loop Road, Belfast BT17 0QL Northern Ireland UKFusion Antibodies is a contract research organisation, which designs, and optimizes therapeutic antibodies for the healthcare market. We help clients solve complex, challenging problems throughout their early discovery antibody programs. Our expertise is defined by our experience. Unique process frameworks, and technology platforms, enable our clients to develop therapeutics within the most challenging modalities and diseases. Guiding clients through early-stage antibody discovery, in the most efficient and effective way, we enable biotechnology and pharmaceutical organizations towards their end-goal – the provision of treatments that improve the lives of patients worldwide. As an independent team, we offer flexibility and agility that antibody discovery and development programs require. Our approach to projects considers long-term impacts on safety, efficacy, and manufacturability at every stage, de-risking antibody programs and maximizing success. As an early discovery partner, our scientists increase the pace to the clinic by guiding clients to develop the best antibodies possible.

Springbank Industrial Estate Pembroke Loop Road Belfast BT17 0QL UKFusion Antibodies is a contract research organisation, which designs, and optimizes therapeutic antibodies for the healthcare market. We help clients solve complex, challenging problems throughout their early discovery antibody programs. Our expertise is defined by our experience. Unique process frameworks, and technology platforms, enable our clients to develop therapeutics within the most challenging modalities and diseases. Guiding clients through early-stage antibody discovery, in the most efficient and effective way, we enable biotechnology and pharmaceutical organizations towards their end-goal – the provision of treatments that improve the lives of patients worldwide. As an independent team, we offer flexibility and agility that antibody discovery and development programs require. Our approach to projects considers long-term impacts on safety, efficacy, and manufacturability at every stage, de-risking antibody programs and maximizing success. As an early discovery partner, our scientists increase the pace to the clinic by guiding clients to develop the best antibodies possible.

7 Isbourne Way, Isbourne Park, Winchcombe, Cheltenham, GL54 5NS, UKGlosfume Provides Intelligent Hot Gas Ceramic Filtration. Internationally recognised for our specialist skill in providing the very best in hot gas ceramic filtration. Glosfume are the only company to manufacture both ceramic elements and filter bodies offering a two year guarantee covering both parts and labour* Advantage of manufacturing our own ceramic and soluble elements enables us to offer higher specification filters at competitive prices. Our standard Ceramic Filter bodies operate at up to 450°C, elements can withstand temperatures of above 1000°C which remove inert sub micron particles from a wide range of gaseous emissions. Typical applications: Foundries. Product recovery. Incineration (W.I.D. compliant). Biomass wood fired boilers. Renewable energy. Acid recovery. Production of nano materials. Gasification.

7 Isbourne Way, Isbourne Park, Winchcombe, Cheltenham, GL54 5NS United KingdomGlosfume Provides Intelligent Hot Gas Ceramic Filtration. Internationally recognised for our specialist skill in providing the very best in hot gas ceramic filtration. Glosfume are the only company to manufacture both ceramic elements and filter bodies offering a two year guarantee covering both parts and labour* Advantage of manufacturing our own ceramic and soluble elements enables us to offer higher specification filters at competitive prices. Our standard Ceramic Filter bodies operate at up to 450°C, elements can withstand temperatures of above 1000°C which remove inert sub micron particles from a wide range of gaseous emissions. Typical applications: Foundries. Product recovery. Incineration (W.I.D. compliant). Biomass wood fired boilers. Renewable energy. Acid recovery. Production of nano materials. Gasification.

Basingstoke, EnglandGenus offers animal breeding, genetic selection, and non-genetically modified livestock.

Unit 4 Heol Aur Dafen Ind Estate Dafen Llanelli Carmarthenshire SA14 8QN

7 Bloomfield Way Debenham, England, IP14 6SJ United KingdomGooderham Horticulture LTD is an independent nursery in UK and the owner Mr. Paul Gooderham having been a horticulturist for over 30 years now is a plant specialist who shares his expert knowledge and provides advice on various aspects. Complete Guidance if you have Discovered a New Plant or are a Breeder on: • New plant development • Plant Trials • Plant Patents • Plant protection • Breeding of protected varieties. We are a company that holds complete understanding and experience in plant breeding of new varieties and their protection. With Paul being in this industry for 3 decades using his knowledge he has been contributing to the development and also in for the marketing of protected of new plant varieties.

36 Gordon Square London WC1H 0PD UNITED KINGDOMGeorge Clinical provides trial management, strategy development, clinical monitoring, and regulatory expertise.

Newcastle upon Tyne, England United KingdomGeneius Laboratories offers microbial testing/identification, GMO testing, and nutritional analysis services.

New Milton, Hampshire, UKGenetix, now part of Molecular Devices, offers screening, genetic services, reagents, imaging, and lab materials.

The Stables, Springfield Farm Lewes Road Haywards Heath, RH17 7NG United KingdomThe company’s research and production divisions focus in particular on the synthesis of benzothiazoles, benzimidazoles, furanes, indoles, isocyanates, isothiocyanates, thiophene derivatives, phosphorus compounds, pyridines, and rare sugars capable of providing these synthetic products from a few grams to many kilograms.

Wythenshawe, Manchester, UKHologic Ltd., trading as Tepnel Pharma Services Overview Supporting Drug Development, Improving Patient Outcomes As part of a leading global healthcare and diagnostics company, our people strive to provide quality control laboratory analysis which helps advance the realisation of precision medicine and a value healthcare system which improves patient outcomes. We believe that it is our responsibility to provide our customers with high quality, regulatory compliant data. Our customers gain access to our knowledge, experience and ability to help them simplify their out-tasking that can work to achieve both incremental and transformational progress towards improving patients’ lives. We are successful because of our People. We are Progressive in our way of thinking. We believe in our Principles. Supporting drug development We focus on the provision of quality control pharmaceutical testing in support of drug development with an emphasis on inhalation, oral dosage, parenteral and peptide formulations. Our people are committed to providing laboratory services that deliver on the promise of quality, through a customer focused performance working alongside you towards a common goal. Our cGMP pharmaceutical testing facility is located in Livingston, Scotland where we work together with our customers and partners building mutual trust through a sharing of knowledge, expertise and teamwork. Our services include: •Lot and batch release testing •ICH stability testing and storage •Raw material and compendial testing •ICH method development and validation Improving patient outcomes Our range of biomarker services cover the spectrum of Research Use Only applications through to design, validation and manufacture of regulatory approved diagnostics. Our people work together with our clients at all stages of their project lifecycle, building relationships and delivering a tailored, bespoke service for academic research, clinical trials or companion diagnostic development. Our genomic service facility is located in Manchester, England where we work together with customers and partners creating tailor made solutions that deliver highly accurate high quality diagnostic results. Our services include: •Research Use Only (RUO) applications and services •GCP applications and services •Diagnostic services and solutions Tepnel Pharma Services is the trading name of the contract services brand of Hologic Ltd., a company registered in the UK (registered number 02722343). cTepnel Pharma Services is a part of Hologic Incorporated, a global healthcare and diagnostics company dedicated to the Science of Sure.

Livingston, West Lothian, UKHologic Ltd., trading as Tepnel Pharma Services Overview Supporting Drug Development, Improving Patient Outcomes As part of a leading global healthcare and diagnostics company, our people strive to provide quality control laboratory analysis which helps advance the realisation of precision medicine and a value healthcare system which improves patient outcomes. We believe that it is our responsibility to provide our customers with high quality, regulatory compliant data. Our customers gain access to our knowledge, experience and ability to help them simplify their out-tasking that can work to achieve both incremental and transformational progress towards improving patients’ lives. We are successful because of our People. We are Progressive in our way of thinking. We believe in our Principles. Supporting drug development We focus on the provision of quality control pharmaceutical testing in support of drug development with an emphasis on inhalation, oral dosage, parenteral and peptide formulations. Our people are committed to providing laboratory services that deliver on the promise of quality, through a customer focused performance working alongside you towards a common goal. Our cGMP pharmaceutical testing facility is located in Livingston, Scotland where we work together with our customers and partners building mutual trust through a sharing of knowledge, expertise and teamwork. Our services include: •Lot and batch release testing •ICH stability testing and storage •Raw material and compendial testing •ICH method development and validation Improving patient outcomes Our range of biomarker services cover the spectrum of Research Use Only applications through to design, validation and manufacture of regulatory approved diagnostics. Our people work together with our clients at all stages of their project lifecycle, building relationships and delivering a tailored, bespoke service for academic research, clinical trials or companion diagnostic development. Our genomic service facility is located in Manchester, England where we work together with customers and partners creating tailor made solutions that deliver highly accurate high quality diagnostic results. Our services include: •Research Use Only (RUO) applications and services •GCP applications and services •Diagnostic services and solutions Tepnel Pharma Services is the trading name of the contract services brand of Hologic Ltd., a company registered in the UK (registered number 02722343). cTepnel Pharma Services is a part of Hologic Incorporated, a global healthcare and diagnostics company dedicated to the Science of Sure.

Appleton Place Appleton Parkway Livingston, West Lothian, EH54 7EZ United KingdomHologic Ltd., trading as Tepnel Pharma Services Overview Supporting Drug Development, Improving Patient Outcomes As part of a leading global healthcare and diagnostics company, our people strive to provide quality control laboratory analysis which helps advance the realisation of precision medicine and a value healthcare system which improves patient outcomes. We believe that it is our responsibility to provide our customers with high quality, regulatory compliant data. Our customers gain access to our knowledge, experience and ability to help them simplify their out-tasking that can work to achieve both incremental and transformational progress towards improving patients’ lives. We are successful because of our People. We are Progressive in our way of thinking. We believe in our Principles. Supporting drug development We focus on the provision of quality control pharmaceutical testing in support of drug development with an emphasis on inhalation, oral dosage, parenteral and peptide formulations. Our people are committed to providing laboratory services that deliver on the promise of quality, through a customer focused performance working alongside you towards a common goal. Our cGMP pharmaceutical testing facility is located in Livingston, Scotland where we work together with our customers and partners building mutual trust through a sharing of knowledge, expertise and teamwork. Our services include: •Lot and batch release testing •ICH stability testing and storage •Raw material and compendial testing •ICH method development and validation Improving patient outcomes Our range of biomarker services cover the spectrum of Research Use Only applications through to design, validation and manufacture of regulatory approved diagnostics. Our people work together with our clients at all stages of their project lifecycle, building relationships and delivering a tailored, bespoke service for academic research, clinical trials or companion diagnostic development. Our genomic service facility is located in Manchester, England where we work together with customers and partners creating tailor made solutions that deliver highly accurate high quality diagnostic results. Our services include: •Research Use Only (RUO) applications and services •GCP applications and services •Diagnostic services and solutions Tepnel Pharma Services is the trading name of the contract services brand of Hologic Ltd., a company registered in the UK (registered number 02722343). cTepnel Pharma Services is a part of Hologic Incorporated, a global healthcare and diagnostics company dedicated to the Science of Sure.

6 Kelvin Park Birkenhead, Merseyside, CH41 1LT United KingdomSupplier of Laboratory Consumables including Certified reference Standards and Materials; Solvents and reagents.

12 Deer Park Road Lombard Business Park Wimbledon London SW19 3FB United KingdomGlentham Life Sciences is a leading supplier of fine chemicals, biochemicals and life science products.

Unit 5 Leafield Way Corsham, Wiltshire, SN13 9SW United KingdomGlentham Life Sciences is a leading supplier of fine chemicals, biochemicals and life science products.

Primerdesign Ltd The Mill Yard Nursling Street Rownhams Southampton United Kingdom SO16 0AJ

Unit 13 Poplars Court, Lenton Lane Nottingham, NG7 2RR United KingdomGxPi offers compliance auditing, training, and consulting services.

Unit 128i Bioscience Centre Business and Innovation Centre Sunderland, SR5 2TA United KingdomGeneblitz offers services including residual DNA testing, genotyping, forensic testing, gene expression, and nucleic acid isolation.

England United KingdomGeneblitz offers services including residual DNA testing, genotyping, forensic testing, gene expression, and nucleic acid isolation.

Block 19 Mereside c/o Logistics Centre Alderley Park Alderley Edge, SK10 4TG United KingdomGentronix Ltd provides predictive toxicology contract research services, with a specialist focus on genetic toxicology, skin toxicology and ocular toxicology. Our expertise and commitment to high quality service enables our clients to gain an early stage view of toxicological hazard, from discovery right through to the GLP regulatory assessments required for pre-clinical or market registration chemical safety evaluation.

Block 23 Mereside Alderley Park Alderley Edge, SK10 4TG United KingdomGentronix Ltd provides predictive toxicology contract research services, with a specialist focus on genetic toxicology, skin toxicology and ocular toxicology. Our expertise and commitment to high quality service enables our clients to gain an early stage view of toxicological hazard, from discovery right through to the GLP regulatory assessments required for pre-clinical or market registration chemical safety evaluation.

30 St Thomas Place Cambridgeshire Business Park Ely Cambridgeshire CB7 4EX UKGregory Fryer Associates provides regulatory, clinical, and quality services.

Unit 5C Leaton Industrial Estate Bomere Heath Shrewsbury Shropshire SY4 3AP United Kingdom

Cragg Vale, England, HX7 5RU United KingdomGenon Laboratories is a UKAS accredited testing laboratory (No. 4149) offering a wide range of specialist food and feed analysis to the global market. We are committed to providing fast turnaround times and a high level of customer service, direct to industry or as a third party service to laboratories. We place a strong emphasis on quality of customer service, ensuring we fully understand your needs, provide a fast turnaround of tests and offer a clear and concise explanation of the results.

P O Box 79 Tadcaster, LS24 0AS United KingdomProf. David Kirkland has more than 30 years experience in regulatory genetic toxicology, and is a renowned expert in the field. For more information see About Me or click here. Many companies experience problems with interpretation of genetic toxicology results, regulatory acceptance of data, and making "go/no go" decisions. Kirkland Consulting offers expert advice on such issues.

Eastcastle House 27/28 Eastcastle Street London, Please select, W1W 8DH United KingdomGPI is your trusted partner, leveraging technology to develop faster, agile, data-driven alternatives to traditional market access and pricing strategy research. Through the power of data analytics we provide high quality, curated insights and recommendations on global drug pricing and market access strategy for the pharma industry. We have created a suite of four unique solutions designed to form an integrated offering to support price and market access strategy throughout the lifecycle, but are flexible enough to be utilised individually. GPI’s suite of technology and bespoke service offerings are powered by GPI pulse™ 2.0, our market leading biopharma data analytics platform. GPI pulse™ utilises powerful algorithms to combine multiple data streams in a way that gives unique insight into the market access journey, helping to drive effective and efficient access to medicines. GPI’s foundation lies within its intelligently integrated price and market access data, but the strength and value is in what we are able to do with it.

64 North Row Mayfair London, W1J 5RL United KingdomGPI is your trusted partner, leveraging technology to develop faster, agile, data-driven alternatives to traditional market access and pricing strategy research. Through the power of data analytics we provide high quality, curated insights and recommendations on global drug pricing and market access strategy for the pharma industry. We have created a suite of four unique solutions designed to form an integrated offering to support price and market access strategy throughout the lifecycle, but are flexible enough to be utilised individually. GPI’s suite of technology and bespoke service offerings are powered by GPI pulse™ 2.0, our market leading biopharma data analytics platform. GPI pulse™ utilises powerful algorithms to combine multiple data streams in a way that gives unique insight into the market access journey, helping to drive effective and efficient access to medicines. GPI’s foundation lies within its intelligently integrated price and market access data, but the strength and value is in what we are able to do with it.

116 Park Street Park House London, W1K 6SS United KingdomGPI is your trusted partner, leveraging technology to develop faster, agile, data-driven alternatives to traditional market access and pricing strategy research. Through the power of data analytics we provide high quality, curated insights and recommendations on global drug pricing and market access strategy for the pharma industry. We have created a suite of four unique solutions designed to form an integrated offering to support price and market access strategy throughout the lifecycle, but are flexible enough to be utilised individually. GPI’s suite of technology and bespoke service offerings are powered by GPI pulse™ 2.0, our market leading biopharma data analytics platform. GPI pulse™ utilises powerful algorithms to combine multiple data streams in a way that gives unique insight into the market access journey, helping to drive effective and efficient access to medicines. GPI’s foundation lies within its intelligently integrated price and market access data, but the strength and value is in what we are able to do with it.

Park Street London, W1K 6SS United KingdomGPI is your trusted partner, leveraging technology to develop faster, agile, data-driven alternatives to traditional market access and pricing strategy research. Through the power of data analytics we provide high quality, curated insights and recommendations on global drug pricing and market access strategy for the pharma industry. We have created a suite of four unique solutions designed to form an integrated offering to support price and market access strategy throughout the lifecycle, but are flexible enough to be utilised individually. GPI’s suite of technology and bespoke service offerings are powered by GPI pulse™ 2.0, our market leading biopharma data analytics platform. GPI pulse™ utilises powerful algorithms to combine multiple data streams in a way that gives unique insight into the market access journey, helping to drive effective and efficient access to medicines. GPI’s foundation lies within its intelligently integrated price and market access data, but the strength and value is in what we are able to do with it.

The Old Barrel Store Draymans Lane Marlow, Buckinghamshire, SL7 2FF United KingdomG&L utilizes decades of experience and a wealth of Subject Matter Expertise in Regulatory Affairs, Quality Assurance and Clinical Development to design and deliver solutions to the biggest challenges faced by global healthcare today. G&L’s reputation for designing and delivering highly effective solutions to the biggest challenges in global healthcare and our commitment to ensuring that our clients’ specific requirements are always met have seen the company experience phenomenal growth since our establishment in 2016. This has been accompanied by increased global client demand for the provision of additional services and solutions that utilize our Regulatory Affairs, Quality Assurance and Clinical Development knowledge and experience to give them a competitive edge. In response, our core services, while committed to Regulatory Affairs, Quality Assurance and Clinical Development, have expanded accordingly. From product development and submissions to company-wide change management, G&L Healthcare Advisors is proud to design, implement, and maintain high-quality, results-focused outcomes for everyone with whom we work.

Draymans Ln Brewery Courtyard England, SL7 2FF United KingdomG&L utilizes decades of experience and a wealth of Subject Matter Expertise in Regulatory Affairs, Quality Assurance and Clinical Development to design and deliver solutions to the biggest challenges faced by global healthcare today. G&L’s reputation for designing and delivering highly effective solutions to the biggest challenges in global healthcare and our commitment to ensuring that our clients’ specific requirements are always met have seen the company experience phenomenal growth since our establishment in 2016. This has been accompanied by increased global client demand for the provision of additional services and solutions that utilize our Regulatory Affairs, Quality Assurance and Clinical Development knowledge and experience to give them a competitive edge. In response, our core services, while committed to Regulatory Affairs, Quality Assurance and Clinical Development, have expanded accordingly. From product development and submissions to company-wide change management, G&L Healthcare Advisors is proud to design, implement, and maintain high-quality, results-focused outcomes for everyone with whom we work.

3 Downshire Place Downshire Place Northern Ireland, BT2 7JQ United KingdomG&L utilizes decades of experience and a wealth of Subject Matter Expertise in Regulatory Affairs, Quality Assurance and Clinical Development to design and deliver solutions to the biggest challenges faced by global healthcare today. G&L’s reputation for designing and delivering highly effective solutions to the biggest challenges in global healthcare and our commitment to ensuring that our clients’ specific requirements are always met have seen the company experience phenomenal growth since our establishment in 2016. This has been accompanied by increased global client demand for the provision of additional services and solutions that utilize our Regulatory Affairs, Quality Assurance and Clinical Development knowledge and experience to give them a competitive edge. In response, our core services, while committed to Regulatory Affairs, Quality Assurance and Clinical Development, have expanded accordingly. From product development and submissions to company-wide change management, G&L Healthcare Advisors is proud to design, implement, and maintain high-quality, results-focused outcomes for everyone with whom we work.

1379 High Road LONDON N20 9LP UKGentaur is a supplier of life science research products.

Unit 224 Edgar Buildings George Street, Bath BA1 2FJ United KingdomGranules offers manufacturing services for API, pharmaceutical formulation intermediates, and finished dosages.

INEX Business Centre, Herschel Building Newcastle Upon Tyne, NE1 7RU United KingdomGenevision offers DNA sequencing and fragment analysis services.

Analytical Chemistry Centre 6 Fen End, Astwick Road Stotfold, Hitchin, SG5 4BA, UKG C Laboratories Ltd was incorporated in 1972 and are thus in our 39th year of successful trading. Over this period we have analysed numerous samples and, as a consequence, have gained a wide and varied client base. A large number of our clients, many 'blue chip' as well as international and foreign companies, have been with us for 25 years or more. Our dedication to analytical excellence has gained us the confidence of major international organisations and governments, our Certificates of Analysis being accepted by companies and regulatory authorities around the world. G C Laboratories has steadily grown since its conception and, as a consequence, in 1998, moved to our much larger premises at Stotfold. G C Laboratories analytical performance and commitment to good science is recognised by the fact that we are accredited to the internationally accepted Good Laboratory Practice (GLP) standard. This very exacting Quality Standard, which is applied to Laboratories worldwide, is overseen in this country by the Medicines Control Agency, and is subject to Statutory Regulation under the UK Good Laboratory Practice Regulations 1999 (SI No. 3106), the Good Laboratory Practice (Codification Amendments, Etc.) Regulations 2004 (SI No.994), and the OECD Principles of Good Laboratory Practice (as revised in 1997) ENV/MC/CHEM(98)17, which are in accordance with the requirements of Directives 2004/9/EC and 2004/10/EC. GC Laboratories Ltd was one of the first laboratories in this country to be accredited to this standard in 1989 and have maintained this accreditation right up to the present day. Copies of our current GLP Certificate are available if required.

Fen End Stotfold, England, SG5 4BA United KingdomG C Laboratories Ltd was incorporated in 1972 and are thus in our 39th year of successful trading. Over this period we have analysed numerous samples and, as a consequence, have gained a wide and varied client base. A large number of our clients, many 'blue chip' as well as international and foreign companies, have been with us for 25 years or more. Our dedication to analytical excellence has gained us the confidence of major international organisations and governments, our Certificates of Analysis being accepted by companies and regulatory authorities around the world. G C Laboratories has steadily grown since its conception and, as a consequence, in 1998, moved to our much larger premises at Stotfold. G C Laboratories analytical performance and commitment to good science is recognised by the fact that we are accredited to the internationally accepted Good Laboratory Practice (GLP) standard. This very exacting Quality Standard, which is applied to Laboratories worldwide, is overseen in this country by the Medicines Control Agency, and is subject to Statutory Regulation under the UK Good Laboratory Practice Regulations 1999 (SI No. 3106), the Good Laboratory Practice (Codification Amendments, Etc.) Regulations 2004 (SI No.994), and the OECD Principles of Good Laboratory Practice (as revised in 1997) ENV/MC/CHEM(98)17, which are in accordance with the requirements of Directives 2004/9/EC and 2004/10/EC. GC Laboratories Ltd was one of the first laboratories in this country to be accredited to this standard in 1989 and have maintained this accreditation right up to the present day. Copies of our current GLP Certificate are available if required.

The Sovereign Centre Farthing Road Ipswich, Suffolk IP1 5AP United KingdomGenevac, a subsidiary of SP Scientific, is a leading manufacturer of specialty equipment for applications in parallel chemistry, proteins, peptides, environmental analysis, and oligonucleotide services.

Ipswich, England United KingdomGenevac, a subsidiary of SP Scientific, is a leading manufacturer of specialty equipment for applications in parallel chemistry, proteins, peptides, environmental analysis, and oligonucleotide services.

97 Vincent Drive Vincent Drive England, B15 2SQ United KingdomPreclinical and discovery-stage pharmacology CRO specialising in receptor occupancy studies, radioligand binding assays, receptor affinity measurements , SPR (Biacore) and autoradiography. Our assays are performed in vitro and ex vivo in cells, membranes, human and animal tissues.

The BioHub Birmingham Birmingham Research Park, Vincent Drive Birmingham, West Midlands, B15 2SQ United KingdomPreclinical and discovery-stage pharmacology CRO specialising in receptor occupancy studies, radioligand binding assays, receptor affinity measurements , SPR (Biacore) and autoradiography. Our assays are performed in vitro and ex vivo in cells, membranes, human and animal tissues.

1 Newstead Rd Weymouth, T4 0AY United KingdomWe produce botanical extracts using liquid CO2 and develop botanical health products made from hemp and other botanical ingredients. We specialize in hemp/cannabis resins produced for the hemp products industry and medical cannabis industry. We also provide contract product development services to create, develop, and market hemp/cannabis products to consumers. We have extensive experience in both the hemp and cannabis industries as well as drug development industry.

11, Progress Business Centre, Whittle Parkway Slough, SL1 6DQ United KingdomGeneron offers protein expression, purification, characterization and custom peptide synthesis services as well as consumables and reagents for purchase.

12 Rawcliffe House, Howarth Road Maidenhead, Berkshire SL6 1AP United KingdomGeneron offers protein expression, purification, characterization and custom peptide synthesis services as well as consumables and reagents for purchase.

Maidenhead, England, SL6 United KingdomGeneron offers protein expression, purification, characterization and custom peptide synthesis services as well as consumables and reagents for purchase.

Unit 9 Kings Meadow Ferry Hinksey Road Oxford, Oxfordshire, OX2 0DP United KingdomGenScript is a leading global biotechnology corporation providing gene, peptide, protein, CRISPR, and antibody services to biotech, pharma, and academic partners worldwide. Based on its independent and superior gene synthesis technology, GenScript has become the largest gene synthesis provider worldwide. Building upon the strengths of next-generation semiconductor-based DNA synthesis, GenScript provides precise mutant library services supporting antibody and protein optimization. Additional specialized services for monoclonal antibody development expedite the discovery of high-quality antibodies with broad epitope specificities in a cost-effective manner. GenScript offers a broad range of catalog products, therapeutic and diagnostic supporting materials, and research instruments to provide scientists worldwide with simple, fast, and effective research solutions. Continued innovation and development of capabilities and resources have enabled GenScript’s impressive business expansion. In addition to its original CRO platform, GenScript has established a contract development and manufacturing organization (CDMO), a global cell therapy group, and an industrial synthetic products platform. These collective platforms enable GenScript to provide comprehensive solutions for biologics’ discovery and development, CAR-T cell therapy strategies, and the development of industrial enzymes. By 2020, GenScript’s workforce of over 3,000 employees, with ~30% holding Master’s and/or Ph.D. degrees, were located in subsidiaries, R&D, and manufacturing facilities across the US, Europe, and Asia. Over the past 18 years, GenScript has grown exponentially through partnerships with scientists conducting basic life science research, translational biomedical research, and early-stage pharmaceutical development.

8 Kingsway Frodsham, Cheshire WA6 6RN United KingdomKingsway Pharma offers consulting services in biotechnology, pharmaceutical manufacturing and devlopment and general management.

Oakfield Avenue Glasgow, Scotland, G12 United KingdomTo provide nanofabrication solutions to industry and academia delivered through the state of the art James Watt Nanofabrication Centre (JWNC) at the University of Glasgow.

11, Pennyman Green Maltby, Middlesbrough TS8 0BX United KingdomKemprotec supplies screening compounds, intermediates and other fine chemicals in addition to offering process development, project management, manufacturing support, and custom synthesis services.

Unit 5, Brunel Drive, Stretton, Burton on Trent,Keats Healthcare sources commercial medicinal products for clinical studies and provides clinical support.

Pitcairn House, First Avenue, Burton upon Trent,Keats Healthcare sources commercial medicinal products for clinical studies and provides clinical support.

MRC-University of Glasgow Centre for Virus Research 8 Church Street Glasgow G11 5JR ScotlandIntroduction Welcome to the Hepatitis C Virus Research UK website. This website aims to supply information relating to HCV for patient, nurse and researcher alike. Here, you will find links to each section which will allow you to find out information on aspects of HCV infection, sample collection, storage and anonymous data collection, all projects/research linked to HCV research UK, relevant HCV news, and more. Contained on this site is information about how to apply for samples for your research project. Click on the bold heading of the desired section below for quick access to that section. About Us HCV Research UK is a consortium of leading figures in the UK from the clinical and scientific community with specific interest in hepatitis C virus (HCV) infection. Its principal objective is to establish a national clinical research database and biobank (a bank of samples) for promoting research studies into HCV infection. Our aim is to create a multidisciplinary infrastructure that links major UK liver centres involved in management of HCV-infected patients to basic science centres of excellence. Within this consortium are also links to the Health Protection Agency (HPA) and Health Protection Scotland (HPS), i.e. the national bodies responsible for monitoring HCV infection in the UK. To achieve these aims, HCV Research UK has been funded by the Medical Research Foundation (MRF) to establish a national cohort of up to 10,000 HCV-infected people recruited from medical centres across the country. This proposed cohort size will support research into a diverse set of questions that are critical for understanding key issues associated with HCV infection such as what factors determine spontaneous clearance of the virus, response to drug therapy, and development of liver disease including cirrhosis and liver cancer.

Keld Close Barker Business Park, Melmerby Green Ln, Melmerby, Ripon HG4 5NB, United KingdomHambleton Ales was established in 1991 in the heart of Hambleton District, North Yorkshire and produces high quality, exceptionally made beers for sale in local pubs and shops. The brewery also offers its years of expertise to other craft breweries in the region by providing contract brewing and packaging services.

Leeds West Yorkshire LS1 6AE UKThe Health and Social Care Information Centre (HSCIC) was set up as an Executive Non Departmental Public Body (ENDPB) in April 2013 .

England United KingdomThe Health and Social Care Information Centre (HSCIC) was set up as an Executive Non Departmental Public Body (ENDPB) in April 2013 .

24 Wordsworth Avenue Cardiff, CF243FR United KingdomHuman Data Sciences is a team of experts practiced in the analysis of healthcare data. We believe in the power of advanced analytics in the transformation of healthcare. Pharmacoepidemiology & Risk Management We design, conduct & support many types of project, including retrospective observational studies and prospective registries, to help you understand – disease distribution – burden of illness – risk factors – treatment patterns – effectiveness & safety Health Economics & Outcomes Research We recognise that reimbursement authorities need real-world data to make crucial decisions about drugs and other treatments. We conduct high-quality studies to deliver health economic evidence, including – burden of illness – comparative effectiveness and – economic value analysis Interpretation & Reporting We not only analyse data on our client’s behalf but interpret results and prepare findings for wide dissemination via reports, abstracts, manuscripts and economic models.

3M Buckley Innovation Centre Firth Street Huddersfield West Yorkshire HD1 3BD United KingdomHere2Grow is a Contract Formulation & Testing Company for cosmetics, laundry, household and car care products, operating from state of the art laboratories at the 3M Buckley Innovation Centre, Huddersfield, UK.

The University of Greenwich, Central Avenue, Chatham, Maritime, Kent ME4 4TB, UKHerbal Analysis Services offers bioassays, spectroscopy, and chromatography services.

New Farm Mire Lane, West End Twyford RG10 0NJ UKHerbiseed has been producing specialist seeds for over 25 years. We specialise in growing seeds of plants derived from wild populations, including weeds, wildflowers, natural herbs and newly domesticated industrial crops. We have farms in England, Serbia and the Philippines which cover cool, warm and tropical climates. This enables us to grow nearly one thousand species of plants, many of which are not available from any other source. We source about 200 species from specialist seed producers, botanic gardens and qualified amateur collectors around the world. Finally, to enable us to provide our customers with a ‘one-stop-shop’ we also stock varieties of common agricultural and horticultural crops from around the world which we purchase from conventional seed merchants.

2 Tower St, Hyde, Cheshire, United Kingdom, SK14 1JW

Tower Street Hyde, England, SK14 1JW United Kingdom

23FC Mereside, Alderley Park, Alderley Edge Cheshire, SK10 4TG United KingdomHelios Medical Communications is a full-service global healthcare communications and strategic consultancy agency. We specialise in delivering high-quality, high-impact bespoke solutions to meet our clients’ needs.

Histologix Ltd Biocity Pennyfoot Street Nottingham NG1 1GFHistologiX is a leading GLP/GCP compliant laboratory delivering cellular and digital pathology services led by science. We pride ourselves in delivering an excellent quality technical service, supporting our clients in the delivery of cutting-edge therapeutics including cell therapies, oncolytic viruses, therapeutic antibodies and RNA modifying enzymes. We offer antibody cross-reactivity testing, antibody screening, histology, and immunohistochemistry services, including ISH (automated RNAscope), whole slide digital scanning and image analysis (HALO software), Veterinary and Medical Pathologist evaluation from discovery, preclinical through to clinical drug development. - our scientific experts will develop, optimise and validate biomarker targets for use in distribution, proof of concept, mechanism of action studies using immunohistochemistry and fluorescence endpoints. - our bespoke tissue cross reactivity service will deliver the required screening assay for regulatory submissions of novel therapeutic agents allowing you to proceed to clinical trial evaluation. - our GCP Clinical Trial Support team has expertise in tissue handling protocols, patient stratification and evaluation of digital pathology end points including analysis of the tumour microenvironment. - our Client Solutions Team will keep you updated throughout the course of your study ensuring project milestones are achieved and your project is delivered successfully. - our aim is to support you in slicing through the timelines of the drug discovery process allowing you to accelerate the development and delivery of tomorrow’s therapeutics.

Biocity Pennyfoot Street Nottingham, NG1 1GF United KingdomHistologiX is a leading GLP/GCP compliant laboratory delivering cellular and digital pathology services led by science. We pride ourselves in delivering an excellent quality technical service, supporting our clients in the delivery of cutting-edge therapeutics including cell therapies, oncolytic viruses, therapeutic antibodies and RNA modifying enzymes. We offer antibody cross-reactivity testing, antibody screening, histology, and immunohistochemistry services, including ISH (automated RNAscope), whole slide digital scanning and image analysis (HALO software), Veterinary and Medical Pathologist evaluation from discovery, preclinical through to clinical drug development. - our scientific experts will develop, optimise and validate biomarker targets for use in distribution, proof of concept, mechanism of action studies using immunohistochemistry and fluorescence endpoints. - our bespoke tissue cross reactivity service will deliver the required screening assay for regulatory submissions of novel therapeutic agents allowing you to proceed to clinical trial evaluation. - our GCP Clinical Trial Support team has expertise in tissue handling protocols, patient stratification and evaluation of digital pathology end points including analysis of the tumour microenvironment. - our Client Solutions Team will keep you updated throughout the course of your study ensuring project milestones are achieved and your project is delivered successfully. - our aim is to support you in slicing through the timelines of the drug discovery process allowing you to accelerate the development and delivery of tomorrow’s therapeutics.

154B Brook Drive Milton Park, Abingdon, Oxfordshire, OX14 4SD United KingdomHypha Discovery Limited - Services Hypha Discovery is a specialist CRO supporting pharmaceutical and agrochemical companies worldwide through the production of metabolites and late-stage derivatives of drugs and agrochemicals in discovery and development. We are experts in the scalable synthesis, purification and identification of drug metabolites and oxidised derivatives of lead compounds, and also possess a wealth of experience in the production, purification and structure elucidation of natural products. For more information visit www.hyphadiscovery.com 1. Custom Metabolite Synthesis and Purification Services Hypha is able to employ multiple tools to achieve successful synthesis of metabolites, comprising microbial biotransformation, mammalian liver fractions (S9 and microsomes), recombinant enzymes, and chemical synthesis, including use of our proprietary late-stage chemical glucuronidation platform. - We can make all phase 1 (CYP and non-CYP) metabolites and phase 2 conjugates (e.g. acyl, O-, & N-glucuronides, sulfates), including difficult-to-synthesise and multi-step metabolites from mg scale for definitive Met ID through to multi-gram scale for toxicology testing - We are experts in the purification of metabolites from complex matrices and clinical samples such as urine, and offer full structure elucidation services, including NMR interpretation as well as Certificates of Analyses. 2. PolarExplorer Service We can achieve late stage diversification of drug compounds through parallel synthesis of multiple hydroxylated derivatives using our proven PolyCYPs enzyme technology. Users of this technology can achieve step-change properties of lead compounds such as increased polarity/potency and improvement in PK properties as well as valuable SAR information. 3. Natural Products Chemistry Hypha has extensive experience in all aspects of natural products chemistry, spanning microbial strain handling, fermentation, yield improvement, through to the purification and structure elucidation of the target compounds. We work flexibly with clients to provide any aspect required, including the production and scale-up of stable and radiolabelled metabolites and natural products.

Bowburn, Durham, EnglandHigh Force Research provides chemical synthesis and R&D for chemical development.

Bowburn North Industrial Estate Bowburn Durham, County Durham, DH6 5PF United KingdomHigh Force Research provides chemical synthesis and R&D for chemical development.

45 Moorfields Moorgate London, London, EC2Y 9AE United KingdomWe are leaders in real world data and digital solutions for healthcare and life sciences, with a clear mission to transform patient outcomes through innovative data & technology solutions.

Newmarket Road Fordham, Cambridgeshire CB7 5WW UKHFL Sport Science, a wholly owned subsidiary of Quotient Bioresearch, offers services for bioanalysis, biomarker measurement, ADME analysis, custom radiochemistry, inmmunoscreening, in vivo PK and safety assessment.

Newcastle Upon Tyne, UKThe MRC-Wellcome Trust Human Developmental Biology Resource (HDBR) is organised from two sites: the Institute of Genetic Medicine, Newcastle, and the Institute of Child Health, London. The HDBR is an ongoing collection of human embryonic and fetal material ranging from 3 to 20 weeks of development. Tissue, slides, RNA/DNA and tissue arrays are available to the international scientific community. Material can either be sent to registered users or our In House Gene Expression Service (IHGES) can carry out projects on user's behalf, providing high quality images and interpretation of gene expression patterns. Gene expression data emerging from HDBR material is added to our gene expression database which is accessible via our HUDSEN (Human Developmental Studies Network) website.

Unit 77, Heyford Park, Upper Heyford Oxfordshire, OX25 5HD, UKHybrid Biosystems offers virus production, purification, characterization, and quantification services.

Oxford, England United KingdomHybrid Biosystems offers virus production, purification, characterization, and quantification services.

Eye Suffolk IP23 7PX UKHuntingdon Life Sciences offers genetic toxicology services and assays for irritation, corrosivity, teratogenicity, permeability, in vitro metabolism, cardiac safety, dermal penetration and microbiological testing.

Woolley Road Alconbury Huntingdon Cambridgeshire PE28 4HS UKHuntingdon Life Sciences offers genetic toxicology services and assays for irritation, corrosivity, teratogenicity, permeability, in vitro metabolism, cardiac safety, dermal penetration and microbiological testing.

Cumberland Avenue London NW10 7EWHammersmith Medicines Research provides phase I services, patient studies, quality services, and regulatory.

London, England United KingdomHammersmith Medicines Research provides phase I services, patient studies, quality services, and regulatory.

7 Whitechapel Road England, E1 United KingdomHealth iQ are leaders in real world data insight We prove and communicate the value of interventions in healthcare for successful market access based on an outstanding healthcare heritage. We work with partners in healthcare, pharmaceuticals and medical devices across Europe. Our award-winning team has worked with 25% of the best selling drugs in recent years and more than half of the top 100 global life science firms now rely on Health iQ's unique insight into real world data. Our market leading products are: - Vantage: The leading online analytics platform for real world data - HiQ Simulation: Animated models that simulate real life healthcare scenarios - LinQ: Real world data insights in bespoke reports and studies - Dynamic Costed Pathways: Map a treatment pathway based on real world data Contact us today if you need support to prove your value with unique insight from the leaders in real world data.

7 Whitechapel Road London, Please Select, E11LN United KingdomHealth iQ are leaders in real world data insight We prove and communicate the value of interventions in healthcare for successful market access based on an outstanding healthcare heritage. We work with partners in healthcare, pharmaceuticals and medical devices across Europe. Our award-winning team has worked with 25% of the best selling drugs in recent years and more than half of the top 100 global life science firms now rely on Health iQ's unique insight into real world data. Our market leading products are: - Vantage: The leading online analytics platform for real world data - HiQ Simulation: Animated models that simulate real life healthcare scenarios - LinQ: Real world data insights in bespoke reports and studies - Dynamic Costed Pathways: Map a treatment pathway based on real world data Contact us today if you need support to prove your value with unique insight from the leaders in real world data.

3rd Floor 1 Ashley Road Altrincham, Cheshire, WA142DT United KingdomHealth iQ are leaders in real world data insight We prove and communicate the value of interventions in healthcare for successful market access based on an outstanding healthcare heritage. We work with partners in healthcare, pharmaceuticals and medical devices across Europe. Our award-winning team has worked with 25% of the best selling drugs in recent years and more than half of the top 100 global life science firms now rely on Health iQ's unique insight into real world data. Our market leading products are: - Vantage: The leading online analytics platform for real world data - HiQ Simulation: Animated models that simulate real life healthcare scenarios - LinQ: Real world data insights in bespoke reports and studies - Dynamic Costed Pathways: Map a treatment pathway based on real world data Contact us today if you need support to prove your value with unique insight from the leaders in real world data.

1-2 Copse Walk Copse Walk Pontprennau, Wales, CF23 8RB United KingdomHEOR Ltd is a leading independent market access consultancy with a reputation for high-quality, innovative market access strategies, evidence generation and value communications. HEOR Ltd acts as a trusted partner to the world’s major pharmaceutical and biopharmaceutical companies. Our in-house teams of technical expert's design, navigate and execute successful market access programmes across the globe. We are a team of over 100 consulting and research professionals based in the UK and Germany and our expertise spans global market access, global health economic modelling, health technology assessment, pricing and reimbursement, national routes to market, pricing, evidence generation, data analytics, value communications, stakeholder engagement, local market development, knowledge services, training and thought leadership. Our clients value our flexibility, integrity to scientific principles and best practice and our ethos of true partnership, where our track record speaks to deep and continuing collaborations for high-value assets across all disease areas and service offerings.

8100 Cambridge Research Park Waterbeach, Cambridge, , CB25 9TL United KingdomBuilt upon decades of experience engineering cell lines, RNA synthesis, and bioinformatic design, we have created a unique portfolio of reagents and services that empower researchers to push their work forward with data generated from cell models. Horizon is leveraging its technological expertise to provide cell engineering tools and services to its customers in three key areas of the therapeutic ecosystem: basic research, drug discovery and development and therapeutic applications. Some of our central services include: • Screening & Cell line engineering services: tools and services that are designed to improve the outcome of drug discovery and development • BioProduction cell lines: engineered CHO cell lines that are designed to enable efficient biologics manufacturing Horizon’s customers include biopharmaceutical and diagnostics companies, contract research and manufacturing organizations and academic researchers across the globe. Horizon sells its tools and services to more than 2,000 unique customers in over 60 countries, including to 19 of the 20 largest biopharmaceutical companies by revenue. On the contract