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Faculté de Médecine / Pharmacie, Site Santé, Domaine de la Merci 23 avenue Maquis du Grésivaudan, 4ème étage, Bâtiment Jean Roget La Tronche, Rhone - Alpes, 38700 FranceGAIA - Gamma Imaging Applications The small animal nuclear imaging platform GAIA (Gamma Imaging Applications) is located in the Laboratory of Bioclinical Radiopharmaceuticals. Over the past 30 years, this laboratory developed a unique expertise in the field of radiopharmaceuticals, including in the selection of the targets to be imaged, the synthesis of ligands, their radiolabeling, their biological evaluations and ultimately the realization of clinical trials. Areas of application include oncology, metabolism, cardiology and neurology. Thanks to the imaging platform GAIA, these well recognized competences are now accessible to industrial as well as academic partners, either as collaborations or services. • The evaluation of the pharmacokinetic and biodistribution of a compound of interest. To fulfill these objectives, the GAIA platform performs the radiolabeling and biological evaluation of the compound of interest. These evaluations can be conducted in various animal models. • The use of a well validated SPECT or PET radiotracer for the characterization of an animal model of interest, or for the evaluation of a new therapeutic compound. To fulfill these objectives, the GAIA platform performs all the biological evaluations. Indeed, many radiotracers are already available, and multiple isotope imaging can be performed. Examples of such studies include the follow up of tumor growth, the evaluation of brain perfusion, as well as the assessment of myocardial perfusion and function.
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