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19C Mereside Alderley Park Nether Alderley, Cheshire, SK10 4TG United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
2350 Rue Cohen Saint-Laurent, Québec, H4R 2N6 CanadaSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
The Discovery Building, BioCity Nottingham Pennyfoot Street Nottingham, Nottinghamshire, NG1 1GR United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
Birchwood House Cheshire Larkwood Way Cheshire, Cheshire, SK10 2XR United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
22F Meresdie Alderley Park Nether Alderley, SK10 4TG United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
22F Mereside Alderley Park Nether Alderley, SK10 4TG United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
Telford Pavilion Todd Campus West of Scotland Science Park Glasgow, Lanarkshire, G20 0XA United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
Pennyfoot Street England, NG1 1GF United KingdomSYGNATURE TOP LEVEL OVERVIEW Introduction -Sygnature Discovery is a fully integrated pre-clinical drug discovery contract research organisation - Facilities are based in the UK and Canada, and span 8 sites - Balanced client portfolio; pharmaceutical industry, biotechnology companies, research organisations and venture capital Quality Metrics - We have an enviable track record of discovering 44 molecules which have progressed into pre-clinical and clinical testing since 2011; 19 pre-clinical, 12 Phase I, 9 Phase II and 4 Phase III - 86% of our business is based on repeat customers -Employees are named as inventors on >170 patent families Staff -Sygnature is stable and scalable with>1000 employees ->900 scientists, 80% of which have a PhD -We are ISO27001 accredited (cyber security) Excellence in Drug Discovery -Delivering standalone and integrated services -Target validation, hit identification, hit to lead, lead optimisation, late lead optimisation, candidate nomination, dose prediction into man -Disciplines: Computer aided drug design, synthetic and medicinal chemistry, in vitro biology, DMPK, in vivo pharmacology, protein sciences, solid form and formulation -Therapeutic areas: oncology, neuroscience, immunology, metabolism, infectious diseases
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