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Parque Tecnologico de Bizkaia Edificio 502 planta 0 Derio, Bizkaia, 48160 SpainRubió Metabolomics (formerly OWL Metabolomics) is a company specialized in metabolomics, with deep expertise in lipidomics, and a growing portfolio of genomic and proteomic services. We also commercialize diagnostic tests for both clinical and research applications. 1. Metabolomics services: Bioanalytical platforms based on ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS) and nuclear magnetic resonance spectroscopy (NMR). - Lipidomics Profiling – more than 1000 lipids detected: Lipidomics – Platform 1: Methanol extraction for the analysis of (more than 300 lipids detected): fatty acyls (non esterified fatty acids, oxidized fatty acids, N-acyl ethanolamines and acylcarnitines), sterol lipids, lysoglycerophospholipids, free sphingoid bases. Lipidomics – Platform 2: Chloroform/methanol extraction for the analysis of (more than 750 lipids detected): fatty acyls (primary fatty amides), sterol lipids, sphingolipids, glycerolipids, glycerophospholipids. Oxidized fatty acids: lipophilic signaling molecules derived from enzymatic and non-enzymatic oxidation of polyunsaturated fatty acids. - Polar Metabolome Platforms – Amino acids and Polar metabolites: Amino acids: Coverage of more than 40 amino acids and derivatives. di- and tripeptides, alpha amino acid derivatives, gamma amino acid derivatives. Polar Metabolites: Water/methanol extraction, available only for tissue or cell/media samples. Main metabolite classes detected: central carbon metabolism intermediates , carboxylic acids, nucleosides and nucleotides, polar vitamins, amino acid derivatives, redox electrocarriers, exogenous or microbial metabolites, miscellaneous polar compounds. - Quantitative Targeted Analysis – Bile acids and tripalmitin. Bile acids: 20 bile acids including free, tauro- and glyco-conjugated bile acids. Tripalmitin: quantification of TG(16:0/16:0/16:0). - NMR Panels (2D-1H-NMR) – Lipoprotein and Glycoprotein Profiling: Lipoprotein profiling: includes lipid content, particle size and particle number. Glycoprotein profiling: Several acute-phase proteins: GlycA, GlycB, GlycF and Height/weight (H/W) ratios of GlycA and GlycB. 2. Proteomic and genomic services: - Targeted detection of protein biomarkers in human body fluids (by PEA and NGS). - Genomic analysis: Sequencing, diagnosis, interpretation, personalization, and clinical genomics. 3. Diagnostic Tests: - OWLiver® – A non-invasive test capable of identifying different stages of MASLD. A serum-based lipidomics test for detecting MASLD, MASH with moderate or no fibrosis (F0–F1), and MASH with significant fibrosis (F≥2). Validated against liver biopsy, it measures 28 blood-based biomarkers to assess liver fat, inflammation, and fibrosis, making it possible to establish the degree of development of the disease. It is a CE-marked with a CPT/PLA code test, available in Europe and the USA for clinical practice and research. - Liposcale® – an advanced lipoprotein profiling test for cardiovascular risk assessment, based on NMR technology. The test allows a comprehensive characterization of the lipid composition, size, and particle number of different lipoproteins. 4. Data Science & Reporting - Data Proccesing – multivariate and univariate statistical analysis, correlation studies and predictive algorithms. - Detailed Study Report – relative or absolute metabolite quantification, statistical comparisons between groups, interpretation of results, experimental methodology, score plots and diagnostic parameters, relevant heatmaps and data visualizations. CONTACT US HERE: metabolomics@labrubio.com
Parque Tecnológico de Bizkaia 502 Building 48160 Derio SpainRubió Metabolomics (formerly OWL Metabolomics) is a company specialized in metabolomics, with deep expertise in lipidomics, and a growing portfolio of genomic and proteomic services. We also commercialize diagnostic tests for both clinical and research applications. 1. Metabolomics services: Bioanalytical platforms based on ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS) and nuclear magnetic resonance spectroscopy (NMR). - Lipidomics Profiling – more than 1000 lipids detected: Lipidomics – Platform 1: Methanol extraction for the analysis of (more than 300 lipids detected): fatty acyls (non esterified fatty acids, oxidized fatty acids, N-acyl ethanolamines and acylcarnitines), sterol lipids, lysoglycerophospholipids, free sphingoid bases. Lipidomics – Platform 2: Chloroform/methanol extraction for the analysis of (more than 750 lipids detected): fatty acyls (primary fatty amides), sterol lipids, sphingolipids, glycerolipids, glycerophospholipids. Oxidized fatty acids: lipophilic signaling molecules derived from enzymatic and non-enzymatic oxidation of polyunsaturated fatty acids. - Polar Metabolome Platforms – Amino acids and Polar metabolites: Amino acids: Coverage of more than 40 amino acids and derivatives. di- and tripeptides, alpha amino acid derivatives, gamma amino acid derivatives. Polar Metabolites: Water/methanol extraction, available only for tissue or cell/media samples. Main metabolite classes detected: central carbon metabolism intermediates , carboxylic acids, nucleosides and nucleotides, polar vitamins, amino acid derivatives, redox electrocarriers, exogenous or microbial metabolites, miscellaneous polar compounds. - Quantitative Targeted Analysis – Bile acids and tripalmitin. Bile acids: 20 bile acids including free, tauro- and glyco-conjugated bile acids. Tripalmitin: quantification of TG(16:0/16:0/16:0). - NMR Panels (2D-1H-NMR) – Lipoprotein and Glycoprotein Profiling: Lipoprotein profiling: includes lipid content, particle size and particle number. Glycoprotein profiling: Several acute-phase proteins: GlycA, GlycB, GlycF and Height/weight (H/W) ratios of GlycA and GlycB. 2. Proteomic and genomic services: - Targeted detection of protein biomarkers in human body fluids (by PEA and NGS). - Genomic analysis: Sequencing, diagnosis, interpretation, personalization, and clinical genomics. 3. Diagnostic Tests: - OWLiver® – A non-invasive test capable of identifying different stages of MASLD. A serum-based lipidomics test for detecting MASLD, MASH with moderate or no fibrosis (F0–F1), and MASH with significant fibrosis (F≥2). Validated against liver biopsy, it measures 28 blood-based biomarkers to assess liver fat, inflammation, and fibrosis, making it possible to establish the degree of development of the disease. It is a CE-marked with a CPT/PLA code test, available in Europe and the USA for clinical practice and research. - Liposcale® – an advanced lipoprotein profiling test for cardiovascular risk assessment, based on NMR technology. The test allows a comprehensive characterization of the lipid composition, size, and particle number of different lipoproteins. 4. Data Science & Reporting - Data Proccesing – multivariate and univariate statistical analysis, correlation studies and predictive algorithms. - Detailed Study Report – relative or absolute metabolite quantification, statistical comparisons between groups, interpretation of results, experimental methodology, score plots and diagnostic parameters, relevant heatmaps and data visualizations. CONTACT US HERE: metabolomics@labrubio.com
101 Ibaizabal Bidea Building 502 Floor 0 Zamudio, PV, 48170 SpainRubió Metabolomics (formerly OWL Metabolomics) is a company specialized in metabolomics, with deep expertise in lipidomics, and a growing portfolio of genomic and proteomic services. We also commercialize diagnostic tests for both clinical and research applications. 1. Metabolomics services: Bioanalytical platforms based on ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS) and nuclear magnetic resonance spectroscopy (NMR). - Lipidomics Profiling – more than 1000 lipids detected: Lipidomics – Platform 1: Methanol extraction for the analysis of (more than 300 lipids detected): fatty acyls (non esterified fatty acids, oxidized fatty acids, N-acyl ethanolamines and acylcarnitines), sterol lipids, lysoglycerophospholipids, free sphingoid bases. Lipidomics – Platform 2: Chloroform/methanol extraction for the analysis of (more than 750 lipids detected): fatty acyls (primary fatty amides), sterol lipids, sphingolipids, glycerolipids, glycerophospholipids. Oxidized fatty acids: lipophilic signaling molecules derived from enzymatic and non-enzymatic oxidation of polyunsaturated fatty acids. - Polar Metabolome Platforms – Amino acids and Polar metabolites: Amino acids: Coverage of more than 40 amino acids and derivatives. di- and tripeptides, alpha amino acid derivatives, gamma amino acid derivatives. Polar Metabolites: Water/methanol extraction, available only for tissue or cell/media samples. Main metabolite classes detected: central carbon metabolism intermediates , carboxylic acids, nucleosides and nucleotides, polar vitamins, amino acid derivatives, redox electrocarriers, exogenous or microbial metabolites, miscellaneous polar compounds. - Quantitative Targeted Analysis – Bile acids and tripalmitin. Bile acids: 20 bile acids including free, tauro- and glyco-conjugated bile acids. Tripalmitin: quantification of TG(16:0/16:0/16:0). - NMR Panels (2D-1H-NMR) – Lipoprotein and Glycoprotein Profiling: Lipoprotein profiling: includes lipid content, particle size and particle number. Glycoprotein profiling: Several acute-phase proteins: GlycA, GlycB, GlycF and Height/weight (H/W) ratios of GlycA and GlycB. 2. Proteomic and genomic services: - Targeted detection of protein biomarkers in human body fluids (by PEA and NGS). - Genomic analysis: Sequencing, diagnosis, interpretation, personalization, and clinical genomics. 3. Diagnostic Tests: - OWLiver® – A non-invasive test capable of identifying different stages of MASLD. A serum-based lipidomics test for detecting MASLD, MASH with moderate or no fibrosis (F0–F1), and MASH with significant fibrosis (F≥2). Validated against liver biopsy, it measures 28 blood-based biomarkers to assess liver fat, inflammation, and fibrosis, making it possible to establish the degree of development of the disease. It is a CE-marked with a CPT/PLA code test, available in Europe and the USA for clinical practice and research. - Liposcale® – an advanced lipoprotein profiling test for cardiovascular risk assessment, based on NMR technology. The test allows a comprehensive characterization of the lipid composition, size, and particle number of different lipoproteins. 4. Data Science & Reporting - Data Proccesing – multivariate and univariate statistical analysis, correlation studies and predictive algorithms. - Detailed Study Report – relative or absolute metabolite quantification, statistical comparisons between groups, interpretation of results, experimental methodology, score plots and diagnostic parameters, relevant heatmaps and data visualizations. CONTACT US HERE: metabolomics@labrubio.com
Parque Tecnológico de Bizkaia Edif. 502, planta 0 Derio, Bizkaia, 48160 SpainRubió Metabolomics (formerly OWL Metabolomics) is a company specialized in metabolomics, with deep expertise in lipidomics, and a growing portfolio of genomic and proteomic services. We also commercialize diagnostic tests for both clinical and research applications. 1. Metabolomics services: Bioanalytical platforms based on ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS) and nuclear magnetic resonance spectroscopy (NMR). - Lipidomics Profiling – more than 1000 lipids detected: Lipidomics – Platform 1: Methanol extraction for the analysis of (more than 300 lipids detected): fatty acyls (non esterified fatty acids, oxidized fatty acids, N-acyl ethanolamines and acylcarnitines), sterol lipids, lysoglycerophospholipids, free sphingoid bases. Lipidomics – Platform 2: Chloroform/methanol extraction for the analysis of (more than 750 lipids detected): fatty acyls (primary fatty amides), sterol lipids, sphingolipids, glycerolipids, glycerophospholipids. Oxidized fatty acids: lipophilic signaling molecules derived from enzymatic and non-enzymatic oxidation of polyunsaturated fatty acids. - Polar Metabolome Platforms – Amino acids and Polar metabolites: Amino acids: Coverage of more than 40 amino acids and derivatives. di- and tripeptides, alpha amino acid derivatives, gamma amino acid derivatives. Polar Metabolites: Water/methanol extraction, available only for tissue or cell/media samples. Main metabolite classes detected: central carbon metabolism intermediates , carboxylic acids, nucleosides and nucleotides, polar vitamins, amino acid derivatives, redox electrocarriers, exogenous or microbial metabolites, miscellaneous polar compounds. - Quantitative Targeted Analysis – Bile acids and tripalmitin. Bile acids: 20 bile acids including free, tauro- and glyco-conjugated bile acids. Tripalmitin: quantification of TG(16:0/16:0/16:0). - NMR Panels (2D-1H-NMR) – Lipoprotein and Glycoprotein Profiling: Lipoprotein profiling: includes lipid content, particle size and particle number. Glycoprotein profiling: Several acute-phase proteins: GlycA, GlycB, GlycF and Height/weight (H/W) ratios of GlycA and GlycB. 2. Proteomic and genomic services: - Targeted detection of protein biomarkers in human body fluids (by PEA and NGS). - Genomic analysis: Sequencing, diagnosis, interpretation, personalization, and clinical genomics. 3. Diagnostic Tests: - OWLiver® – A non-invasive test capable of identifying different stages of MASLD. A serum-based lipidomics test for detecting MASLD, MASH with moderate or no fibrosis (F0–F1), and MASH with significant fibrosis (F≥2). Validated against liver biopsy, it measures 28 blood-based biomarkers to assess liver fat, inflammation, and fibrosis, making it possible to establish the degree of development of the disease. It is a CE-marked with a CPT/PLA code test, available in Europe and the USA for clinical practice and research. - Liposcale® – an advanced lipoprotein profiling test for cardiovascular risk assessment, based on NMR technology. The test allows a comprehensive characterization of the lipid composition, size, and particle number of different lipoproteins. 4. Data Science & Reporting - Data Proccesing – multivariate and univariate statistical analysis, correlation studies and predictive algorithms. - Detailed Study Report – relative or absolute metabolite quantification, statistical comparisons between groups, interpretation of results, experimental methodology, score plots and diagnostic parameters, relevant heatmaps and data visualizations. CONTACT US HERE: metabolomics@labrubio.com
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