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9 Kloosterstraat Building OP Oss, Noord-Brabant, 5349 AB NetherlandsQTM BioSciences offers subcellular drug quantification services through a unique label-free platform that enables direct and quantitative assessment of drug distribution within cells. Our approach combines rapid tag-based purification of cellular compartments with high-resolution measurement of bound and unbound levels in both cytosol and organelles. In collaborations with pharmaceutical partners, this technology has revealed critical insights into intracellular trafficking of ADCs, LNP cargoes, and small molecules - covering cellular uptake, endo-lysosomal processing, and organelle distribution kinetics. It has guided the selection of optimal payloads, explained variability in efficacy, and revealed mechanisms such as bystander effects. Additionally, our platform provides valuable data on how small molecules and other modalities distribute across organelles like lysosomes and mitochondria, informing the development of metabolic and other intracellularly targeted therapies. By making subcellular drug exposure measurable, QTM Biosciences supports a deeper mechanistic understanding and enables the rational design and optimization of new therapies.
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The Contract Research Map is owned and maintained by Scientist.com. It was created to help researchers in the life sciences identify and connect with contract research organizations (CROs) based on geography. Updated nightly, this map features all of the available CROs within our network, so you can order services with a few clicks. Click on a specific country, scroll on the map itself or type into the search bar at the top—there are many ways to find the location and suppliers that you’re looking for. From Argentina to New Zealand, use this map to connect with a CRO near you.
We believe that every researcher across the world should be able to connect with the thousands of global CROs that exist and have the opportunity to work together. Like many industries,the life science supply chain has been disrupted over the last year. But there are many other circumstances such as international customs regulations or sensitive shipping times that create limitations around which countries are feasible to partner with. Sometimes, finding a CRO based in a country that best suits your research needs is imperative. We hope this contract research map allows you to find the right partner in the right place at the right time.
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