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Imperial College White City IHub 84 Wood Lane London, W12 0BZ United KingdomPear Bio is a computational biology company that has developed a functional precision medicine platform to guide therapy choice in cancer patients, based on growing patients' tumors in a lab and performing therapy dosing on parallel microtumors to assess response. The platform uses organ-on-a-chip and computer vision to measure cancer progression over time. Pear Bio cultures patient tumor samples and tests potential treatment options and combinations ex vivo. A proprietary computer vision/ML pipeline finds image-based spatial biomarkers in time-course 3D microscopy data of the patient tumor cultures. The platform has applications in drug development (including combination therapy screening) and clinical biomarkers. Pear Bio can provide lab services including: - Compound screening - 3D image analysis/computer vision services - Combination therapy synergy testing - Drug translation services using primary tumors - Clinical biomarkers and patient stratification
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