Hestehavevej 36A, Ejby Lille Skensved, 4623 DenmarkScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

Karolinska Science Park Nobels väg 16 Solna, 171 65 SwedenScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

Medicon Village Sheelevägen 2 Lund, 223 63 SwedenScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

AstraZeneca BioVentureHub Pepparedsleden 3 Gothenburg, Mölndal, 431 83 SwedenScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

Energivej 42 Pepparedsleden 3 Ballerup, 2750 DenmarkScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

AstraZeneca BioVentureHub Pepparedsleden 3 Mölndal, 431 83 SwedenScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

Energivej 42 Ballerup, 2750 DenmarkScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

Alderley Park, Alderley Edge Cheshire, SK10 4TG United KingdomScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.

Parkring 12 Grambach, 8074 AustriaScantox: Scientific Excellence in Preclinical Research 47+ Years as a Trusted Partner | AAALAC-Accredited | GLP Facilities Scantox is a leading nonclinical CRO with AAALAC-accredited facilities offering integrated discovery-to-IND services. With 47+ years of experience, our nonclinical capabilities span discovery pharmacology, genetic and regulatory toxicology, pharmaceutical development, and bioanalysis. With direct access to senior scientists and a commitment to scientific excellence, we serve as a trusted partner to pharmaceutical, biotech and medical device companies. Our comprehensive services enable clients to seamlessly advance drug and device development, delivering consistent, high-quality data to the highest technical and scientific standards. Key Differentiators • AAALAC-Accredited Animal Welfare & Technical Excellence – Excellence in animal care with first-in-class indoor/outdoor facilities, complemented by highly tenured technical staff holding 4-year related degrees for exceptional study consistency • Göttingen Minipig Center of Excellence – Industry-leading expertise in large animal safety studies with dedicated facilities and specialized staff trained in large animal research methodologies • Specialized Neuropharmacology Capabilities – Advanced CNS disease models and rare disease expertise spanning neurological research with sophisticated behavioral and physiological endpoints • ESG Leadership – Commitment to sustainable business practices reflected with EcoVadis Bronze Medal in 2025 Core Services • Discovery Pharmacology – In vitro and in vivo model expertise with specialization in CNS neuropharmacology therapeutics, rare neurodegenerative diseases, and comprehensive pharmacological profiling • Regulatory Toxicology – Exploratory tox, TK and PK/PD studies as well as GLP IND-enabling safety studies. General toxicology, juvenile and reproductive toxicology. Extensive experience in rodent and non-rodent species. Standard routes of admin: Oral (via gavage or using capsules/tablets), dermal, intramuscular, subcutaneous, and intravenous. Non-standard routes: Topical to the eye, intravitreal, intraperitoneal, and rectal • Genetic Toxicology – Regulatory genotoxicity assessments, early screening and evaluation • Pharmaceutical Development – Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials • Bioanalytical Services [LC-MS/MS platforms] – Method development, validation, and sample analysis for all study phases Service Details Discovery Pharmacology [Neuropharmacology expertise] Comprehensive pharmacological profiling with specialized expertise in CNS diseases, rare diseases, and mental disorders through our neuropharmacology division. Advanced disease models and screening platforms support mechanism of action studies, efficacy assessments, and dose-response characterizations across therapeutic areas with integrated PK/PD analysis. Regulatory Toxicology [Göttingen Minipig leadership] Full spectrum of GLP-compliant preclinical toxicology studies with recognized leadership in Göttingen Minipig safety assessments. Our operational depth covers anesthesia protocols, dosing procedures, sampling techniques, and endpoint assessments with robust historical control databases. Comprehensive capabilities include acute and chronic toxicity, carcinogenicity, reproductive and developmental toxicology, immunotoxicology, and safety pharmacology evaluations across diverse species selection. Genetic Toxicology [Complete screening battery] Comprehensive portfolio of screening and regulatory genotoxicity services including bacterial reverse mutation (Ames), mammalian cell gene mutation studies, chromosome aberration tests, and micronucleus assays. Specialized assessment of photosensitivity potential with clear regulatory pathway guidance. Pharmaceutical Development [Formulation and clinical support] Formulation development and dose formulation manufacturing with complete logistics support for Phase 1 and 2 clinical trials. Services span from traditional small molecules through complex biologics, ensuring seamless progression from preclinical development through early clinical phases. Bioanalytical Services [LC-MS/MS platforms] Comprehensive LC-MS/MS method development, validation, and sample analysis for exploratory, regulatory, and clinical studies. Full-service capabilities include handling of complex compounds and controlled substances with established quality systems for global regulatory compliance. Integrated Service Platform Our multidisciplinary approach from discovery pharmacology through regulatory submission enables clients to progress development projects with consistent quality standards and streamlined communication. Multidisciplinary teams coordinate across pharmacology, toxicology, pathology, formulation, and bioanalysis with unified project management.