1000 Waterview Drive Hamilton, NJ 08691 USAInvivotek is a global pre-clinical contract research organization (CRO) specializing in small animal studies for drug discovery and early optimization. Invivotek offers both custom and standard pre-clinical services for drug discovery and development programs for our clients. Invivotek’s portfolio includes animal models and bioassays designed to support in vivo testing of compounds related to Immunology and Inflammation, Oncology, Metabolic, and Cardiovascular diseases. Invivotek’s in vivo testing capabilities are supported by biochemical and molecular biology techniques as well as functional assays with primary cell cultures established from various mouse tissues under disease model and normal conditions. These assays provide tools to study the mechanism of action of various test therapeutics or potential target genes and to explore drug efficacy biomarkers. • Evaluation of test therapeutics in rodent models of human disease o Oncology and Immuno-Oncology  Efficacy studies o Immunology & Inflammation  Animal Disease Models  Non-Disease in vivo Bioassays  Ex vivo Bioassays o Metabolic Diseases  Animal Disease Models  In Vivo Energy Homeostasis and Body Composition Assessment  Glucose Homeostasis and diabetes-related complications  Lipid Metabolism and NASH  Cardiovascular Function o Neuoroscience  Behavioral tests of anxiety  Opioid withdrawal models  Acute nociception and chronic pain models In Vivo Oncology Models Syngeneic Tumor Models Xenograft Tumor Models Orthotopic Tumor Models Abscopal Tumor Models CDX Tumor Models In Vivo IVIS Imaging IVIS imaging CRO Bioluminescent imaging Tumor monitoring by IVIS imaging Radiation Therapy in mouse tumor Radiation Therapy in mouse tumor CRO CAR-T Efficacy studies Cell viability assay Carcinogenecity Assays CRO Doppler blood perfusion imager Immunology and Inflammation FACs Analysis CRO FACS Analysis of Lymphoid Organs FACS Analysis of Immune Cells Immune cell Profiling by Flow Cytometry Immune Profiling by Flow Cytometry

17 Black Forest Road Hamilton, NJ, 08691 United StatesInvivotek is a global pre-clinical contract research organization (CRO) specializing in small animal studies for drug discovery and early optimization. Invivotek offers both custom and standard pre-clinical services for drug discovery and development programs for our clients. Invivotek’s portfolio includes animal models and bioassays designed to support in vivo testing of compounds related to Immunology and Inflammation, Oncology, Metabolic, and Cardiovascular diseases. Invivotek’s in vivo testing capabilities are supported by biochemical and molecular biology techniques as well as functional assays with primary cell cultures established from various mouse tissues under disease model and normal conditions. These assays provide tools to study the mechanism of action of various test therapeutics or potential target genes and to explore drug efficacy biomarkers. • Evaluation of test therapeutics in rodent models of human disease o Oncology and Immuno-Oncology  Efficacy studies o Immunology & Inflammation  Animal Disease Models  Non-Disease in vivo Bioassays  Ex vivo Bioassays o Metabolic Diseases  Animal Disease Models  In Vivo Energy Homeostasis and Body Composition Assessment  Glucose Homeostasis and diabetes-related complications  Lipid Metabolism and NASH  Cardiovascular Function o Neuoroscience  Behavioral tests of anxiety  Opioid withdrawal models  Acute nociception and chronic pain models In Vivo Oncology Models Syngeneic Tumor Models Xenograft Tumor Models Orthotopic Tumor Models Abscopal Tumor Models CDX Tumor Models In Vivo IVIS Imaging IVIS imaging CRO Bioluminescent imaging Tumor monitoring by IVIS imaging Radiation Therapy in mouse tumor Radiation Therapy in mouse tumor CRO CAR-T Efficacy studies Cell viability assay Carcinogenecity Assays CRO Doppler blood perfusion imager Immunology and Inflammation FACs Analysis CRO FACS Analysis of Lymphoid Organs FACS Analysis of Immune Cells Immune cell Profiling by Flow Cytometry Immune Profiling by Flow Cytometry