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2571 US Route 11 LaFayette, NY, 13083 United StatesIchor Life Sciences is a premier boutique preclinical and clinical trial services partner. Ichor has specialization in In vivo and In vitro Pharmacology, as well as Protein Sciences and Structure Based Drug Discovery. Please scroll down to view some of our media & posters, and for custom inquiries, please feel free to Contact Us! Biophysics and Biophysical Assays: Ichor has numerous capabilities within biophysics, including SPR , BLI, ITC, FP, FRET, NMR, and MLS. Our extensive knowledge in this field allows for fast turnaround times. Within the capabilities, we can use this for binding thermodynamics, kinetics, stoichiometry, stability/release as well as functional analysis. Ichor also has capabilities and knowledge with plate-based assay services. Structural Biology: Ichor's structural biology services include primary crystal screening, optimization screens, protein modification, protein-ligand complexes, X-ray data collection, structure determination and X-Ray Crystallography. The use of Formulatrix NT8 Crystallization robot and Rock Imager 1000 allow for fast turnaround from protein to crystal screens. Ichor also offers CryoTEM, and Bioanalytical Mass Spectrometry Our binding assays, Structure Based Drug Design (SBDD) SHG, Thermostability, and Fragment Based Screening, can support your most challenging research projects. Protein Expression and Purification: Ichor's services include mammalian, insect, bacteria and yeast expression. We do expression scouting, purification scouting, as well as offer quality proteins and formulation. Ichor's expression designs include Rational Design, and Machine Learning/DoE. Molecular Pharmacology: Ichor's molecular pharmacology group is the central node for the drug discovery process. We deploy a variety of state-of-the-art techniques to draw reliable, accurate and fast conclusions in-vitro, which allows for seamless transition to in-vivo studies. Our world class scientists utilize the best equipment on the market including Operetta, IncuCyte and Leica imaging systems. Ophthalmology: We have expertise with diagnostic equipment and use advanced tissue collection techniques including histology and bioanalysis within mice and rats. Our models include intraocular pressure, Uveitis including both experimental autoimmune and endotoxin induced. Our other services include Fundoscopy, Optic Nerve Crush, Optical Coherence Tomography, Irritation and Tolerability, Macular Degeneration, Corneal Wound Healing, CNV and Ocular Tissue Harvesting. Pharmacology: We offer a wide range of preclinical services including in-vitro testing, in-vivo efficacy, and non-GLP toxicology. We specialize in preclinical PK/PD and efficacy models in oncology, metabolic diseases including fatty liver disease, NASH, NAFLD, HFD, diet-induced obesity and geriatric models. NASH Models: -High Fat Diet (HFD), C57BL/6 -Carbon Tetrachloride (CCL4), BALB/c -Streptozotocin (STZ) + HFD, C57BL/6 (6 wk and pups) -HFD, ob/ob - Friedman (Western diet + CCL4), C57BL/6 -Thioacetamide (TAA), Sprague Dawley Rats -Chronic/Aged NASH, 30 wk C57BL/6 Oncology Models : Syngeneic Models: -4T1: Mammary Cancer - B16-F10: Melanoma - CT-26: Colon Carcinoma -EMT6: Mammary Carcinoma -LL/2: Lewis Lung Carcinoma -MOC2: Oral Squamous Cell Carcinoma -Renca: Renal Adenocarcinoma -UNKC-6141: Pancreatic Ductal Adenocarcinoma Xenograft Models: -A375: Melanoma -A549: Lung Carcinoma -HCT116: Colorectal Carcinoma -MCF7: Breast Cancer -Panc-1: Pancreas -U-87 MG: Glioblastoma Geriatric Models: -Wound healing models (also have young, standard models) -Senescent models -Life span models -Standard models in geriatric phenotype -New model development
2561 US Route 11 LaFayette, NY, 13084 United StatesIchor Life Sciences is a premier boutique preclinical and clinical trial services partner. Ichor has specialization in In vivo and In vitro Pharmacology, as well as Protein Sciences and Structure Based Drug Discovery. Please scroll down to view some of our media & posters, and for custom inquiries, please feel free to Contact Us! Biophysics and Biophysical Assays: Ichor has numerous capabilities within biophysics, including SPR , BLI, ITC, FP, FRET, NMR, and MLS. Our extensive knowledge in this field allows for fast turnaround times. Within the capabilities, we can use this for binding thermodynamics, kinetics, stoichiometry, stability/release as well as functional analysis. Ichor also has capabilities and knowledge with plate-based assay services. Structural Biology: Ichor's structural biology services include primary crystal screening, optimization screens, protein modification, protein-ligand complexes, X-ray data collection, structure determination and X-Ray Crystallography. The use of Formulatrix NT8 Crystallization robot and Rock Imager 1000 allow for fast turnaround from protein to crystal screens. Ichor also offers CryoTEM, and Bioanalytical Mass Spectrometry Our binding assays, Structure Based Drug Design (SBDD) SHG, Thermostability, and Fragment Based Screening, can support your most challenging research projects. Protein Expression and Purification: Ichor's services include mammalian, insect, bacteria and yeast expression. We do expression scouting, purification scouting, as well as offer quality proteins and formulation. Ichor's expression designs include Rational Design, and Machine Learning/DoE. Molecular Pharmacology: Ichor's molecular pharmacology group is the central node for the drug discovery process. We deploy a variety of state-of-the-art techniques to draw reliable, accurate and fast conclusions in-vitro, which allows for seamless transition to in-vivo studies. Our world class scientists utilize the best equipment on the market including Operetta, IncuCyte and Leica imaging systems. Ophthalmology: We have expertise with diagnostic equipment and use advanced tissue collection techniques including histology and bioanalysis within mice and rats. Our models include intraocular pressure, Uveitis including both experimental autoimmune and endotoxin induced. Our other services include Fundoscopy, Optic Nerve Crush, Optical Coherence Tomography, Irritation and Tolerability, Macular Degeneration, Corneal Wound Healing, CNV and Ocular Tissue Harvesting. Pharmacology: We offer a wide range of preclinical services including in-vitro testing, in-vivo efficacy, and non-GLP toxicology. We specialize in preclinical PK/PD and efficacy models in oncology, metabolic diseases including fatty liver disease, NASH, NAFLD, HFD, diet-induced obesity and geriatric models. NASH Models: -High Fat Diet (HFD), C57BL/6 -Carbon Tetrachloride (CCL4), BALB/c -Streptozotocin (STZ) + HFD, C57BL/6 (6 wk and pups) -HFD, ob/ob - Friedman (Western diet + CCL4), C57BL/6 -Thioacetamide (TAA), Sprague Dawley Rats -Chronic/Aged NASH, 30 wk C57BL/6 Oncology Models : Syngeneic Models: -4T1: Mammary Cancer - B16-F10: Melanoma - CT-26: Colon Carcinoma -EMT6: Mammary Carcinoma -LL/2: Lewis Lung Carcinoma -MOC2: Oral Squamous Cell Carcinoma -Renca: Renal Adenocarcinoma -UNKC-6141: Pancreatic Ductal Adenocarcinoma Xenograft Models: -A375: Melanoma -A549: Lung Carcinoma -HCT116: Colorectal Carcinoma -MCF7: Breast Cancer -Panc-1: Pancreas -U-87 MG: Glioblastoma Geriatric Models: -Wound healing models (also have young, standard models) -Senescent models -Life span models -Standard models in geriatric phenotype -New model development
Peyton Hall 65 Main Street Potsdam, NY, 13676 United StatesIchor Life Sciences is a premier boutique preclinical and clinical trial services partner. Ichor has specialization in In vivo and In vitro Pharmacology, as well as Protein Sciences and Structure Based Drug Discovery. Please scroll down to view some of our media & posters, and for custom inquiries, please feel free to Contact Us! Biophysics and Biophysical Assays: Ichor has numerous capabilities within biophysics, including SPR , BLI, ITC, FP, FRET, NMR, and MLS. Our extensive knowledge in this field allows for fast turnaround times. Within the capabilities, we can use this for binding thermodynamics, kinetics, stoichiometry, stability/release as well as functional analysis. Ichor also has capabilities and knowledge with plate-based assay services. Structural Biology: Ichor's structural biology services include primary crystal screening, optimization screens, protein modification, protein-ligand complexes, X-ray data collection, structure determination and X-Ray Crystallography. The use of Formulatrix NT8 Crystallization robot and Rock Imager 1000 allow for fast turnaround from protein to crystal screens. Ichor also offers CryoTEM, and Bioanalytical Mass Spectrometry Our binding assays, Structure Based Drug Design (SBDD) SHG, Thermostability, and Fragment Based Screening, can support your most challenging research projects. Protein Expression and Purification: Ichor's services include mammalian, insect, bacteria and yeast expression. We do expression scouting, purification scouting, as well as offer quality proteins and formulation. Ichor's expression designs include Rational Design, and Machine Learning/DoE. Molecular Pharmacology: Ichor's molecular pharmacology group is the central node for the drug discovery process. We deploy a variety of state-of-the-art techniques to draw reliable, accurate and fast conclusions in-vitro, which allows for seamless transition to in-vivo studies. Our world class scientists utilize the best equipment on the market including Operetta, IncuCyte and Leica imaging systems. Ophthalmology: We have expertise with diagnostic equipment and use advanced tissue collection techniques including histology and bioanalysis within mice and rats. Our models include intraocular pressure, Uveitis including both experimental autoimmune and endotoxin induced. Our other services include Fundoscopy, Optic Nerve Crush, Optical Coherence Tomography, Irritation and Tolerability, Macular Degeneration, Corneal Wound Healing, CNV and Ocular Tissue Harvesting. Pharmacology: We offer a wide range of preclinical services including in-vitro testing, in-vivo efficacy, and non-GLP toxicology. We specialize in preclinical PK/PD and efficacy models in oncology, metabolic diseases including fatty liver disease, NASH, NAFLD, HFD, diet-induced obesity and geriatric models. NASH Models: -High Fat Diet (HFD), C57BL/6 -Carbon Tetrachloride (CCL4), BALB/c -Streptozotocin (STZ) + HFD, C57BL/6 (6 wk and pups) -HFD, ob/ob - Friedman (Western diet + CCL4), C57BL/6 -Thioacetamide (TAA), Sprague Dawley Rats -Chronic/Aged NASH, 30 wk C57BL/6 Oncology Models : Syngeneic Models: -4T1: Mammary Cancer - B16-F10: Melanoma - CT-26: Colon Carcinoma -EMT6: Mammary Carcinoma -LL/2: Lewis Lung Carcinoma -MOC2: Oral Squamous Cell Carcinoma -Renca: Renal Adenocarcinoma -UNKC-6141: Pancreatic Ductal Adenocarcinoma Xenograft Models: -A375: Melanoma -A549: Lung Carcinoma -HCT116: Colorectal Carcinoma -MCF7: Breast Cancer -Panc-1: Pancreas -U-87 MG: Glioblastoma Geriatric Models: -Wound healing models (also have young, standard models) -Senescent models -Life span models -Standard models in geriatric phenotype -New model development
831 JAMES ST FL 2 SYRACUSE, NY, 13203 United StatesIchor Life Sciences is a premier boutique preclinical and clinical trial services partner. Ichor has specialization in In vivo and In vitro Pharmacology, as well as Protein Sciences and Structure Based Drug Discovery. Please scroll down to view some of our media & posters, and for custom inquiries, please feel free to Contact Us! Biophysics and Biophysical Assays: Ichor has numerous capabilities within biophysics, including SPR , BLI, ITC, FP, FRET, NMR, and MLS. Our extensive knowledge in this field allows for fast turnaround times. Within the capabilities, we can use this for binding thermodynamics, kinetics, stoichiometry, stability/release as well as functional analysis. Ichor also has capabilities and knowledge with plate-based assay services. Structural Biology: Ichor's structural biology services include primary crystal screening, optimization screens, protein modification, protein-ligand complexes, X-ray data collection, structure determination and X-Ray Crystallography. The use of Formulatrix NT8 Crystallization robot and Rock Imager 1000 allow for fast turnaround from protein to crystal screens. Ichor also offers CryoTEM, and Bioanalytical Mass Spectrometry Our binding assays, Structure Based Drug Design (SBDD) SHG, Thermostability, and Fragment Based Screening, can support your most challenging research projects. Protein Expression and Purification: Ichor's services include mammalian, insect, bacteria and yeast expression. We do expression scouting, purification scouting, as well as offer quality proteins and formulation. Ichor's expression designs include Rational Design, and Machine Learning/DoE. Molecular Pharmacology: Ichor's molecular pharmacology group is the central node for the drug discovery process. We deploy a variety of state-of-the-art techniques to draw reliable, accurate and fast conclusions in-vitro, which allows for seamless transition to in-vivo studies. Our world class scientists utilize the best equipment on the market including Operetta, IncuCyte and Leica imaging systems. Ophthalmology: We have expertise with diagnostic equipment and use advanced tissue collection techniques including histology and bioanalysis within mice and rats. Our models include intraocular pressure, Uveitis including both experimental autoimmune and endotoxin induced. Our other services include Fundoscopy, Optic Nerve Crush, Optical Coherence Tomography, Irritation and Tolerability, Macular Degeneration, Corneal Wound Healing, CNV and Ocular Tissue Harvesting. Pharmacology: We offer a wide range of preclinical services including in-vitro testing, in-vivo efficacy, and non-GLP toxicology. We specialize in preclinical PK/PD and efficacy models in oncology, metabolic diseases including fatty liver disease, NASH, NAFLD, HFD, diet-induced obesity and geriatric models. NASH Models: -High Fat Diet (HFD), C57BL/6 -Carbon Tetrachloride (CCL4), BALB/c -Streptozotocin (STZ) + HFD, C57BL/6 (6 wk and pups) -HFD, ob/ob - Friedman (Western diet + CCL4), C57BL/6 -Thioacetamide (TAA), Sprague Dawley Rats -Chronic/Aged NASH, 30 wk C57BL/6 Oncology Models : Syngeneic Models: -4T1: Mammary Cancer - B16-F10: Melanoma - CT-26: Colon Carcinoma -EMT6: Mammary Carcinoma -LL/2: Lewis Lung Carcinoma -MOC2: Oral Squamous Cell Carcinoma -Renca: Renal Adenocarcinoma -UNKC-6141: Pancreatic Ductal Adenocarcinoma Xenograft Models: -A375: Melanoma -A549: Lung Carcinoma -HCT116: Colorectal Carcinoma -MCF7: Breast Cancer -Panc-1: Pancreas -U-87 MG: Glioblastoma Geriatric Models: -Wound healing models (also have young, standard models) -Senescent models -Life span models -Standard models in geriatric phenotype -New model development
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