Dubai Silicon Oasis, DDP, Building A1 Dubai, Dubai, 000000 United Arab EmiratesIBS GL – FZCO (IBS GL) is a fast-growing Dubai-based Human Biospecimens CRO building a sourcing and processing network across MENAT and Central Asia—regions with large, fast-growing populations and rising healthcare needs. Due to cultural and regulatory challenges, they remain underrepresented in biopharma and diagnostics R&D, offering significant untapped potential. IBS GL serves as the central hub for customer interactions and project management, overseeing all regional activities conducted by its subsidiaries and directly contracted local partners. This structure simplifies client access to IBS GL’s full capabilities and streamlines financial transactions across the network. Collection locations: Armenia, Tajikistan, Kazakhstan, Turkey, Georgia, Argentina, Bulgaria. Additional collection sites are developed in the UAE (via partnership with Khalifa University, Abu Dhabi), Saudi Arabia (with leading medical universities), Egypt (through the Arab Biobanking Network), and Ethiopia (in collaboration with AHRI, the country’s leading medical research institute with its own clinical sites). Biospecimens collection capabilities: Diseases/TAs: Solid oncology, hematology and onco-hematology, rheumatology-inflammation (RA, PsA, SLE, Myasthenia Gravis, etc.), neurology, dermatology, gastroenterology (UC, Crohn’s, pancreatic and liver diseases), ophthalmology, infection, pediatrics, orphan/rare diseases. Collection from normal controls is also possible. Importantly, the range of therapeutic areas and types of biospecimens we can collect continues to evolve with the growth of our clinical network and is driven by customer demand. Biospecimen types/formats: TISSUE SAMPLES (SURGICAL AND BIOPSIES) AND DERIVATIVES • Formalin-fixed paraffin-embedded (FFPE) blocks • Flash-frozen (FF) tissue samples • Fresh tissue - availability depends on the location of the site where samples have to be delivered and delivery time/shipment condition requirements • Unstained FFPE slides • H&E stained FFPE slides • Frozen O.C.T.-embedded samples • Tissue sections/curls from FFPE blocks • Tissue samples stabilized in RNAlater reagent • Viable tissue fragments in a cryomedia Histological images (micro- and macro) are often available or can be produced by request. Multiple samples/biopsies from different regions, e.g. tumor and NAT, affected and not affected regions, are possible for oncology, dermatology, gastroenterology. BIOFLUIDS AND DERIVATIVES Common types of biofluids: • Whole blood • Bone marrow aspirate (BMA) • Whol urine • Saliva • Exudate • Ascitic fluid • Synovial fluid • Cerebrospinal Fluid (CSF) • Wound fluid Biofluid derivatives: • Plasma, single and double-spun (custom protocols welcome) • Serum • Buffy coat • Peripheral blood mononuclear cells (PBMC, viable and flash-frozen) • Blood smears • Stabilized blood (in PAXgene tubes) • Dried blood spots • Flash-frozen bone marrow aspirate (BMA FF) • Bone marrow mononuclear cells (BMMC, viable and flash-frozen) • Bone marrow aspirate smears • Stabilized bone marrow aspirate (in PAXgene tubes) • Isolated urine cells (viable and flash-frozen) • Frozen urine supernatant • Frozen whole saliva • Stabilized saliva (DNA stabilizer) • Frozen whole exudate • Isolated urine cells (viable and flash-frozen) • Frozen exudate supernatant • Frozen whole ascitic fluid • Frozen filtered ascitic fluid • Isolated ascitic fluid cells (viable and flash-frozen) • Frozen ascitic fluid supernatant • Frozen whole synovial fluid • Isolated synovial fluid cells (viable and flash-frozen) • Frozen synovial fluid supernatant • Frozen cerebrospinal fluid (CSF) • Frozen sputum • Frozen bronchoalveolar lavage (BAL) • Frozen BAL cell concentrate • Frozen BAL supernatant • Wound fluid OTHER • Swabs (nasopharyngeal, oropharyngeal, buccal, vaginal, urinary) • Feces • Hair • Breast milk samples • Aqueous humor • Intestinal fluid: a mix of pancreatic juice and bile samples • Samples collected from a specific part of GI tract. Biorepository: In addition to prospective collection and access to clinical archives or partner-held pre-existing collections, IBS GL maintains its own diverse biorepository: https://ibsgl.com/biorpository. Detailed inventories of many biospecimens are available on our website, with more being added regularly. Capabilities of that may be of particular interest: - Large collection of oncology and non-oncology FFPE samples (inventory available). - CSF from diseased subject and healthy controls (inventory available). - Aqueous humor from PM and live subjects (inventory available). - Rare/genetic/orphan diseases (inventory available). - Schizophrenia: blood and serum from 1200 fully consented patients (Schizophrenia.xlsx). - Neurological disorders, e.g. ALS, Alzheimer's, etc. - Intestinal Fluid: a mix of bile and pancreatic juice obtained using the proprietary device PandiCath® developed by our sister company PANDICA LTD. The biomaterial is obtained directly from the duodenum without artificial stimulation (e.g. by secretin) and is free from gastric contamination. Volumes exceeding 100 mL per subject are achievable, and detailed inventory is available. This biomaterial has already been used by pharmaceutical clients for applications such as drug solubility testing. PandiCath® also enables collection from other targeted GI segments and supports precise delivery of substances into specific intestinal sites for controlled exposure and local absorption studies. For more information, please contact: vitali.proutski@pandica.com. - Multiple samples and sample types collected at multiple time-points. - Follow-up information for samples collected from archives or prospectively. - Biomarker information available for many samples and can be generated prospectively by PCR or NGS (inventory of mutation-positive and negative FFPE samples and FFPE + plasma matched sets available). Ethics: As expected, we collect biospecimens only from clinical partners with whom we have formal contractual agreements. All prospective collections are conducted under approved informed consent forms (ICFs) reviewed by local or national ethics committees (IRBs). Archival samples are collected either with previously obtained consent, actively re-consented during the project, or under waiver of consent (WoC), as applicable. We maintain full transparency regarding the ethical coverage of each collection.