Reset Map3 Results
2277 Thunderstick Dr. #500 Lexington, KY, 40505 United StatesHera BioLabs is a contract research organization (CRO) utilizing gene editing technologies to create novel cell lines and enabling preclinical research models for oncology & immuno-oncology. Hera’s platform model, the OncoRat SRG, is a SCID rat on the Sprague-Dawley background harboring a double knockout for the Rag2 and Il2rgamma genes. This enhanced immunodeficient rat model has a severely impaired immune system lacking B-cells, T-cells, and NK-cells. Hera’s mission with the OncoRat is to provide the best in vivo data with the fewest number of animals. Improved engraftment rates and growth profile reduce the number of animals that need to be inoculated for a xenograft efficacy study (see PDX and VCaP example). Pharmacokinetics and toxicology can be combined with efficacy in the rat. Serial blood sampling for PK and biomarkers (see VCaP tumor PSA biomarker) as well as serial tumor biopsies can be taken from the larger tumors. All these translational enhancements are realized without the need to remove animals from the study. While the long timeline required for the establishment of patient derived xenografts or PDX models in mice is often impractical; the OncoRat grows ~10x larger tumors enabling PDX establishment and efficacy studies in fewer passages and a shorter amount of time.
145 Graham Ave. #A115 Lexington, KY 40506 United StatesHera BioLabs is a contract research organization (CRO) utilizing gene editing technologies to create novel cell lines and enabling preclinical research models for oncology & immuno-oncology. Hera’s platform model, the OncoRat SRG, is a SCID rat on the Sprague-Dawley background harboring a double knockout for the Rag2 and Il2rgamma genes. This enhanced immunodeficient rat model has a severely impaired immune system lacking B-cells, T-cells, and NK-cells. Hera’s mission with the OncoRat is to provide the best in vivo data with the fewest number of animals. Improved engraftment rates and growth profile reduce the number of animals that need to be inoculated for a xenograft efficacy study (see PDX and VCaP example). Pharmacokinetics and toxicology can be combined with efficacy in the rat. Serial blood sampling for PK and biomarkers (see VCaP tumor PSA biomarker) as well as serial tumor biopsies can be taken from the larger tumors. All these translational enhancements are realized without the need to remove animals from the study. While the long timeline required for the establishment of patient derived xenografts or PDX models in mice is often impractical; the OncoRat grows ~10x larger tumors enabling PDX establishment and efficacy studies in fewer passages and a shorter amount of time.
2277 Thunderstick Drive, STE 500 Lexington, KY 40505, USHera BioLabs is a contract research organization (CRO) utilizing gene editing technologies to create novel cell lines and enabling preclinical research models for oncology & immuno-oncology. Hera’s platform model, the OncoRat SRG, is a SCID rat on the Sprague-Dawley background harboring a double knockout for the Rag2 and Il2rgamma genes. This enhanced immunodeficient rat model has a severely impaired immune system lacking B-cells, T-cells, and NK-cells. Hera’s mission with the OncoRat is to provide the best in vivo data with the fewest number of animals. Improved engraftment rates and growth profile reduce the number of animals that need to be inoculated for a xenograft efficacy study (see PDX and VCaP example). Pharmacokinetics and toxicology can be combined with efficacy in the rat. Serial blood sampling for PK and biomarkers (see VCaP tumor PSA biomarker) as well as serial tumor biopsies can be taken from the larger tumors. All these translational enhancements are realized without the need to remove animals from the study. While the long timeline required for the establishment of patient derived xenografts or PDX models in mice is often impractical; the OncoRat grows ~10x larger tumors enabling PDX establishment and efficacy studies in fewer passages and a shorter amount of time.
Site Information
The Contract Research Map is owned and maintained by Scientist.com. It was created to help researchers in the life sciences identify and connect with contract research organizations (CROs) based on geography. Updated nightly, this map features all of the available CROs within our network, so you can order services with a few clicks. Click on a specific country, scroll on the map itself or type into the search bar at the top—there are many ways to find the location and suppliers that you’re looking for. From Argentina to New Zealand, use this map to connect with a CRO near you.
We believe that every researcher across the world should be able to connect with the thousands of global CROs that exist and have the opportunity to work together. Like many industries,the life science supply chain has been disrupted over the last year. But there are many other circumstances such as international customs regulations or sensitive shipping times that create limitations around which countries are feasible to partner with. Sometimes, finding a CRO based in a country that best suits your research needs is imperative. We hope this contract research map allows you to find the right partner in the right place at the right time.
Have questions or feedback? We’d love to help. You can find our FAQs and contact information on the Learn more page.
Interested in connecting with one or more of the contract research organizations listed on this map? By clicking on the company’s name, you will be directed to their supplier profile on the Scientist.com marketplace. Once you set up a marketplace account you can start the ordering process immediately.
What is Scientist.com?
Scientist.com is the world's largest enterprise marketplace for outsourced R&D services. It saves time and money and provides access to innovation while maintaining compliance with an organization’s procurement policies.
How can I use Scientist.com?
Scientist.com has built private, enterprise marketplaces from 24 of the 30 largest pharmaceutical companies, 80+ biotech companies, the US National Institutes of Health (NIH) and numerous other pharma and biotech companies. If you are employed by one of these organizations, you can log in to get started today. If you are unsure about how to get started, you can email our team at support@scientist.com or go to our website www.scientist.comto speak to someone via our live chat.
Why should I place my order through Scientist.com?
Scientist.com is a highly efficient enterprise-wide outsourcing marketplace that makes it possible for research organizations to save time and money, access innovation and ensure compliance. It utilizes a universal legal agreement and AI technologies to enable research like never before. See how comparing proposals and getting 1-on-1 support from our Research Concierge® team will enable you to place more research today.
How do I get my organization listed on the map?
If your CRO isn’t showing up on the map, then please be sure your company profile is up to date in Scientist.com’s Backoffice. After logging in, click the Your Company button in the navigation at the top, and then select the Locations tab.
Information about my organization is incorrect, how do I fix it?
Head over to backoffice.scientist.com to update your supplier profile and information. It may take up to two business days for the updates to be reflected on the map.