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32980 Alvarado Niles Rd., CELLTHEON/SUITE 826 United States UNION CITY, CA, 94587 United StatesLocated in the San Francisco Bay Area – a center of excellence in Biotechnology, Celltheon is a leader in mammalian expression technology development. Celltheon's proprietary, mammalian expression platform, the Celltheon SMART™ Platform, improves cell line stability and productivity of recombinant antibodies, Fc-fusion proteins, Fabs, difficult to express proteins and more. The Celltheon SMART™ Platform enables rapid delivery of purified protein for in vivo studies, high-expressing manufacturing cell lines and scalable/transferable upstream and downstream processes. Celltheon routinely provides the following services: - Non-GMP Bioproduction & Purification of Expressed Protein (1 - 50L) - Transient Transfections within 10 days (variant screening or protein production) - Stable Pool Development within 2 weeks with titers >1.5g/L (ideal for protein production for early in vivo studies) - Cell Line Development and Research Cell Banking with titers >6gL (completed in <4 months) - Process Optimization Services (Upstream Media/ Feeds, Bioreactor Process Parameters, Purification Processes) to increase expression, product quality, purity and yields - Analytics (cell based assays, various HPLC assays, binding assays, LAL Endotoxin, Host Cell Protein, etc.) The Celltheon SMART™ technology platform has been used to generate several novel and biosimilar molecules ranging in advancement from pre-clinical development to Phase 3. To date, Celltheon has expressed and optimized >1000 molecules for 100+ repeat clients. Celltheon works with several small to large pharmaceutical companies in the U.S and globally to provide SMART solutions for a number of disease indications such as oncology, inflammation, neurodegeneration, obesity, lysosomal storage disorders and more. Our services are highly collaborative, well-documented and timely, giving you control over the entire process. Celltheon will assign a project manager to oversee your project from start to end, ensuring a direct line of communication at all times. Additional services that are complimentary to Celltheon's workflow but not provided directly by Celltheon are outsourced to third party partners, these services will be managed by Celltheon for the client's convenience. For additional information about our technology and services, please review our corporate presentation or request a meeting with Celltheon's technical team. We are happy to provide a consultation specific to your project via teleconference in order to provide an accurate estimate.
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