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Heinrich-Plett-Str. 40 Geb. AVZ 2, Rm. 3125-3132 Kassel, HE, 34132 GermanyBiaffin GmbH & Co KG is an ISO 9001:2015 certified bioanalytical service provider specialized in the application of biosensors based on surface plasmon resonance (SPR) for biomolecular interaction analysis (BIA). BIA technology is ideally suited for highly accurate kinetic characterization of any interacting molecules in real-time in a label-free state. Biaffin has extensive knowledge and many years of experience in various application areas and supports biopharmaceutical drug development programs of pharma, biotech and generic drug companies as well as scientific institutions worldwide as a competent partner. The service is performed by a highly specialized team (PhD level scientists) in a laboratory well equipped with several state-of-the art SPR instruments (5x Biacore T200, 1x Biacore 8K+, 1x Biacore 1S+). Sufficient capacity of SPR instruments allows Biaffin to start interaction studies on short notice, quickly run multiple projects in parallel and receive results in a timely manner. A qualified Biacore T200 instrument is available for SPR assay validation and SPR analysis under GMP conditions. Highly accurate SPR assays for many target proteins and biosimilars are already established and available off the shelf, and established protocols can rapidly be adapted to new target proteins using specific capture assays. ADCC SPR assays are established for interaction analysis of antibodies with Fc gamma receptors (CD16, CD32, CD64) including receptor variants and different species, neonatal Fc receptor (FcRn) and complement C1q binding. The company’s expertise is documented by many peer-reviewed publications in renowned scientific journals.
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