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via Provinciale Schito 131 Torre Annunziata, Naples, 80058 ItalyAxxam is an iPRO (innovative Partner Research Organization) providing services in early drug discovery across the entire Life Science industries: Pharmaceutical, Crop protection, Animal health, Cosmetics and Nutrition. Our main skills are: - High Throughput Screening (HTS) campaigns using client’s own compound collections or our compound collection of up to 400.000 novel and diverse small molecules (divided into 5 subsets which can be screened separately according to the project's needs. - Assay development (biochemical or cell-based) and phenotypic assays for compound testing activities and HTS. - Ready for use assays for compound testing activities and HTS. - High Content Screening (HCS) campaigns (on up to 20.000 compounds) and Phenotypic analysis: autophagy, neurite outgrowth, cell cicle, citotoxicity, mitochondrial analysis, marker localization, DNA damage, translocation, aggregation assays. - Hit follow-up activities: compound profiling, specificity, selectivity, ortholog and orthogonal assays, among others. - Molecular biology: gene editing, gene expression analysis, TaqMan screening, splice modulators and promoter activation assays. - iPSC-derived cells (neurons, cardiomyocytes, microglia cells, myotubes, hepatocites, macrophages): calcium oscillation, aggregation assays, imaging, electrophysiology, cytokine release, citotoxicity, disease models. - Electrophysiology: manual patch clamp, automated patch clamp suitable for HTS, organellar patch clamp (lysosomes, mitochondria, nuclei), optogenetics. - Biophysical tools: affinity measurement, Kd determination, spectral shift, molecular interactions, microscale thermophoresis. - Radiometric assays: Scintillation Proximity Assay (SPA), radiometric high throughput screening - Analytical chemistry: LC-MS analysis, chiral resolution, kinetic solubility Thanks to our commitment to science, we are involved in the most innovative research areas including the use of iPSC-derived cells, gene editing, optogenetics, lysosomal diseases, protein degradation, molecular interactions, and RNA splicing.
Via Meucci 3 Bresso, 20091 ItalyAxxam is an iPRO (innovative Partner Research Organization) providing services in early drug discovery across the entire Life Science industries: Pharmaceutical, Crop protection, Animal health, Cosmetics and Nutrition. Our main skills are: - High Throughput Screening (HTS) campaigns using client’s own compound collections or our compound collection of up to 400.000 novel and diverse small molecules (divided into 5 subsets which can be screened separately according to the project's needs. - Assay development (biochemical or cell-based) and phenotypic assays for compound testing activities and HTS. - Ready for use assays for compound testing activities and HTS. - High Content Screening (HCS) campaigns (on up to 20.000 compounds) and Phenotypic analysis: autophagy, neurite outgrowth, cell cicle, citotoxicity, mitochondrial analysis, marker localization, DNA damage, translocation, aggregation assays. - Hit follow-up activities: compound profiling, specificity, selectivity, ortholog and orthogonal assays, among others. - Molecular biology: gene editing, gene expression analysis, TaqMan screening, splice modulators and promoter activation assays. - iPSC-derived cells (neurons, cardiomyocytes, microglia cells, myotubes, hepatocites, macrophages): calcium oscillation, aggregation assays, imaging, electrophysiology, cytokine release, citotoxicity, disease models. - Electrophysiology: manual patch clamp, automated patch clamp suitable for HTS, organellar patch clamp (lysosomes, mitochondria, nuclei), optogenetics. - Biophysical tools: affinity measurement, Kd determination, spectral shift, molecular interactions, microscale thermophoresis. - Radiometric assays: Scintillation Proximity Assay (SPA), radiometric high throughput screening - Analytical chemistry: LC-MS analysis, chiral resolution, kinetic solubility Thanks to our commitment to science, we are involved in the most innovative research areas including the use of iPSC-derived cells, gene editing, optogenetics, lysosomal diseases, protein degradation, molecular interactions, and RNA splicing.
Via Meucci 3, Bresso 20091, Milano, ItalyAxxam is an iPRO (innovative Partner Research Organization) providing services in early drug discovery across the entire Life Science industries: Pharmaceutical, Crop protection, Animal health, Cosmetics and Nutrition. Our main skills are: - High Throughput Screening (HTS) campaigns using client’s own compound collections or our compound collection of up to 400.000 novel and diverse small molecules (divided into 5 subsets which can be screened separately according to the project's needs. - Assay development (biochemical or cell-based) and phenotypic assays for compound testing activities and HTS. - Ready for use assays for compound testing activities and HTS. - High Content Screening (HCS) campaigns (on up to 20.000 compounds) and Phenotypic analysis: autophagy, neurite outgrowth, cell cicle, citotoxicity, mitochondrial analysis, marker localization, DNA damage, translocation, aggregation assays. - Hit follow-up activities: compound profiling, specificity, selectivity, ortholog and orthogonal assays, among others. - Molecular biology: gene editing, gene expression analysis, TaqMan screening, splice modulators and promoter activation assays. - iPSC-derived cells (neurons, cardiomyocytes, microglia cells, myotubes, hepatocites, macrophages): calcium oscillation, aggregation assays, imaging, electrophysiology, cytokine release, citotoxicity, disease models. - Electrophysiology: manual patch clamp, automated patch clamp suitable for HTS, organellar patch clamp (lysosomes, mitochondria, nuclei), optogenetics. - Biophysical tools: affinity measurement, Kd determination, spectral shift, molecular interactions, microscale thermophoresis. - Radiometric assays: Scintillation Proximity Assay (SPA), radiometric high throughput screening - Analytical chemistry: LC-MS analysis, chiral resolution, kinetic solubility Thanks to our commitment to science, we are involved in the most innovative research areas including the use of iPSC-derived cells, gene editing, optogenetics, lysosomal diseases, protein degradation, molecular interactions, and RNA splicing.
Byk-Gulden Strasse 2 Constance, BW, 78467 GermanyAxxam is an iPRO (innovative Partner Research Organization) providing services in early drug discovery across the entire Life Science industries: Pharmaceutical, Crop protection, Animal health, Cosmetics and Nutrition. Our main skills are: - High Throughput Screening (HTS) campaigns using client’s own compound collections or our compound collection of up to 400.000 novel and diverse small molecules (divided into 5 subsets which can be screened separately according to the project's needs. - Assay development (biochemical or cell-based) and phenotypic assays for compound testing activities and HTS. - Ready for use assays for compound testing activities and HTS. - High Content Screening (HCS) campaigns (on up to 20.000 compounds) and Phenotypic analysis: autophagy, neurite outgrowth, cell cicle, citotoxicity, mitochondrial analysis, marker localization, DNA damage, translocation, aggregation assays. - Hit follow-up activities: compound profiling, specificity, selectivity, ortholog and orthogonal assays, among others. - Molecular biology: gene editing, gene expression analysis, TaqMan screening, splice modulators and promoter activation assays. - iPSC-derived cells (neurons, cardiomyocytes, microglia cells, myotubes, hepatocites, macrophages): calcium oscillation, aggregation assays, imaging, electrophysiology, cytokine release, citotoxicity, disease models. - Electrophysiology: manual patch clamp, automated patch clamp suitable for HTS, organellar patch clamp (lysosomes, mitochondria, nuclei), optogenetics. - Biophysical tools: affinity measurement, Kd determination, spectral shift, molecular interactions, microscale thermophoresis. - Radiometric assays: Scintillation Proximity Assay (SPA), radiometric high throughput screening - Analytical chemistry: LC-MS analysis, chiral resolution, kinetic solubility Thanks to our commitment to science, we are involved in the most innovative research areas including the use of iPSC-derived cells, gene editing, optogenetics, lysosomal diseases, protein degradation, molecular interactions, and RNA splicing.
Via Campestre 33 Bresso, MI, 20091 ItalyAxxam is an iPRO (innovative Partner Research Organization) providing services in early drug discovery across the entire Life Science industries: Pharmaceutical, Crop protection, Animal health, Cosmetics and Nutrition. Our main skills are: - High Throughput Screening (HTS) campaigns using client’s own compound collections or our compound collection of up to 400.000 novel and diverse small molecules (divided into 5 subsets which can be screened separately according to the project's needs. - Assay development (biochemical or cell-based) and phenotypic assays for compound testing activities and HTS. - Ready for use assays for compound testing activities and HTS. - High Content Screening (HCS) campaigns (on up to 20.000 compounds) and Phenotypic analysis: autophagy, neurite outgrowth, cell cicle, citotoxicity, mitochondrial analysis, marker localization, DNA damage, translocation, aggregation assays. - Hit follow-up activities: compound profiling, specificity, selectivity, ortholog and orthogonal assays, among others. - Molecular biology: gene editing, gene expression analysis, TaqMan screening, splice modulators and promoter activation assays. - iPSC-derived cells (neurons, cardiomyocytes, microglia cells, myotubes, hepatocites, macrophages): calcium oscillation, aggregation assays, imaging, electrophysiology, cytokine release, citotoxicity, disease models. - Electrophysiology: manual patch clamp, automated patch clamp suitable for HTS, organellar patch clamp (lysosomes, mitochondria, nuclei), optogenetics. - Biophysical tools: affinity measurement, Kd determination, spectral shift, molecular interactions, microscale thermophoresis. - Radiometric assays: Scintillation Proximity Assay (SPA), radiometric high throughput screening - Analytical chemistry: LC-MS analysis, chiral resolution, kinetic solubility Thanks to our commitment to science, we are involved in the most innovative research areas including the use of iPSC-derived cells, gene editing, optogenetics, lysosomal diseases, protein degradation, molecular interactions, and RNA splicing.
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