Buechelstr. 54 Remscheid, 10713 Germany ATEM Structural Discovery, a leading Contract Research Organization (CRO), specializes in analytical and structural cryo-electron microscopy (cryo-EM). Our state-of-the-art, fully commercial cryo-EM laboratory is equipped with an integrated wet lab, a Talos L120 room temperature microscope (ThermoFisher), and a Glacios cryo-EM system featuring an advanced direct electron detector camera (ThermoFisher). Additionally, we have an on-premises high-performance computational cluster. Our primary strength lies in our highly integrated process, encompassing everything from sample preparation to result analysis, all within a single facility. We are at the forefront of developing proprietary Artificial Intelligence (AI) software for industrial applications in this field. As a Good Manufacturing Practice (GMP) certified laboratory, we adhere to the highest standards of quality. Our services include: - Cell Line Characterization and Bulk Harvest Analysis: GMP-compliant analysis for viral contamination studies. - Lipid-Nano-Particle (LNP) Characterization: Utilizing the first AI-based solution for transforming images into fully quantitative data, aiding in formulation, stability studies, and batch-to-batch controls. - Adeno-Associated Viral Vector (AAV) Characterization: Providing high-precision results from single-particle cryo-EM imaging for comprehensive characterization, including full, empty, and intermediate states. - 3D Structure Epitope and Paratope Mapping: Streamlined cryo-EM process enabling detailed insights for antibody and biologics discovery, aiding in lead candidate selection or optimization. - 3D Structure Mode of Action Study: Specialized in small molecules, offering extensive capabilities to enhance key quality attributes relevant to cryo-EM structure determination. Our visualization capabilities extend across various modalities, including cells, nanoparticles, viruses and virus-like particles, and proteins. By leveraging our expertise and cutting-edge technology, ATEM Structural Discovery is committed to advancing scientific understanding and supporting the development of novel solutions in the field of structural biology.

Büchelstraße 54 Remscheid, 42855 Germany ATEM Structural Discovery, a leading Contract Research Organization (CRO), specializes in analytical and structural cryo-electron microscopy (cryo-EM). Our state-of-the-art, fully commercial cryo-EM laboratory is equipped with an integrated wet lab, a Talos L120 room temperature microscope (ThermoFisher), and a Glacios cryo-EM system featuring an advanced direct electron detector camera (ThermoFisher). Additionally, we have an on-premises high-performance computational cluster. Our primary strength lies in our highly integrated process, encompassing everything from sample preparation to result analysis, all within a single facility. We are at the forefront of developing proprietary Artificial Intelligence (AI) software for industrial applications in this field. As a Good Manufacturing Practice (GMP) certified laboratory, we adhere to the highest standards of quality. Our services include: - Cell Line Characterization and Bulk Harvest Analysis: GMP-compliant analysis for viral contamination studies. - Lipid-Nano-Particle (LNP) Characterization: Utilizing the first AI-based solution for transforming images into fully quantitative data, aiding in formulation, stability studies, and batch-to-batch controls. - Adeno-Associated Viral Vector (AAV) Characterization: Providing high-precision results from single-particle cryo-EM imaging for comprehensive characterization, including full, empty, and intermediate states. - 3D Structure Epitope and Paratope Mapping: Streamlined cryo-EM process enabling detailed insights for antibody and biologics discovery, aiding in lead candidate selection or optimization. - 3D Structure Mode of Action Study: Specialized in small molecules, offering extensive capabilities to enhance key quality attributes relevant to cryo-EM structure determination. Our visualization capabilities extend across various modalities, including cells, nanoparticles, viruses and virus-like particles, and proteins. By leveraging our expertise and cutting-edge technology, ATEM Structural Discovery is committed to advancing scientific understanding and supporting the development of novel solutions in the field of structural biology.