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Asterand, A BioIVT Company

C/O Wilmington Trust SP GmbH Steinweg 3-5 Frankfurt am Main , 60313 GermanyWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture

Asterand, A BioIVT Company

440 Burroughs TechOne, Suite 501 Detroit, Michigan, 48202 United StatesWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture

Asterand, A BioIVT Company

2 Orchard Road Royston, Herts SG8 5HD United KingdomWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture

Asterand, A BioIVT Company

Tech One Bldg Ste 501 440 Burroughs Detroit MI 48202-3420 USAWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture

Asterand, A BioIVT Company

Tech One Bldg Ste 501 440 Burroughs Detroit MI 48202-3420 USAWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture

Asterand, A BioIVT Company

123 Frost Street Suite 115 Westbury, NY, 11590 United StatesWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture

Asterand, A BioIVT Company

440 Burroughs Street Detroit, MI, 48202 United StatesWho We Are Asterand Bioscience is now part of BioIVT. The addition of ASTERAND (founded in 2000 as a human tissue bank) to the BioIVT family of brands, means BioIVT is uniquely positioned to provide a comprehensive approach to meet your biospecimen and related service needs. The companies combine to become the leader of high quality, well-characterized human tissue solutions to drug and diagnostic development scientists. As such, BioIVT continues to partner with you to provide human-based solutions to accelerate the validation of drug targets, enhance the selection of drug candidates with an increased likelihood of clinical success and support clinical diagnostic assay development and testing. With our expanded capabilities in human tissue procurement, characterization and research tools, our employees focus on providing the services and products that help you succeed. Our Products Our expanded capabilities provide you with solutions in human and animal biologics, from Normal to Diseased State, Biofluids to Tissues. BioIVT’s ASTERAND human tissues are procured through an unparalleled worldwide network of over 200 active collaborative donor institutions. Our biobank contains several hundred thousand specimens from a broad range of therapeutic areas and with many ethnicities. Our tissues provide high value to our clients because the quantity of material provided for each sample allows scientists to conduct multiple experiments using a single specimen. In addition, our renowned quality assurance procedures provide stringent controls on specimen collection and characterization and on the corresponding clinical data. As part of this process, we also independently confirm pathology and assess RNA integrity of our tissues. Our quality control results are provided to researchers before they make their purchases. This enables researchers to choose samples that will best meet their scientific requirements. Through our custom procurement service, human tissues and clinical data can also be custom collected to meet special requirements. Additional Information Human Tissue, Biofluid, Immune Cells and Primary Cells As the leading provider of high quality human tissue, biofluids, immune cells and primary cells with associated clinical information BioIVT’s human biospecimens are procured and quality controlled following rigorous criteria. We acquire biospecimens through different procurement means to best meet the supply demand of our customers through an IRB-approved process. Our bank includes material that is prospectively obtained in a variety of formats including fresh frozen and FFPE, as well as biofluids. We offer tissue sets collected as mirrored and/or matched pairs or as a quad set. In addition, we offer immortalized cell lines, primary cells, immune cells tissue microarrays as well as biospecimen services such as the creation of tissue derivatives. Custom Procurement of Human Tissue and Biofluid BioIVT offers human tissues and clinical data custom collected to meet unique research requirements within a wide range of disease categories. Samples are provided in multiple preserved formats or as fresh and unpreserved biospecimens. For biofluids, specific coagulants and processing can be performed for fit-for-purpose collection. As a result, we deliver human tissue, biofluid and accompanying clinical information that is most compatible with your experimental design. With our exceptional network we are able to offer tissue and biofluid custom collected in various formats across a broad therapeutic offering. Biospecimen Services Our laboratories provide a number of biospecimen services to better enable and accelerate the research of our customers. Our team of highly trained PhD scientists, Scientists, certified Histologists and Board Certified Clinical Pathologists offer a range of contract research and core services designed to serve your needs. Histology/Pathology Services Immunohistochemistry Mutation Screening Flow Cytometry Custom Tissue Microarrays (Frozen and FFPE Tissue, Cell Lines) Primary Cell Isolation and Culture Molecular Pathology Services ADME-Tox Services ADMET Hepatoxicity Metabolism Liver Disease Modeling Hepatobiliary Disposition Drug-Drug Interactions (DDI) Supporting Services Custom Tissue Microarrays Gene mutation analysis (including KRAS, EGFR, Her2) Primary cell isolation and culture