225 E. Chicago Ave. Chicago, IL 60611Following the opening of Lurie Children's, a Research Histology Core has been established at Manne Research Institute to provide scientists histology services in house within a short period of time and at minimal costs. Equipment is available to process fixed tissue, embed in paraffin, section them and make routine hematoxylin and eosin staining as well as to perform immunohistochemistry and some special staining. Staff members are available for technical consultation regarding optimal harvesting and fixation of tissues, stains, histopathological procedures as well as for professional pathologic consultation and even imaging. Specimen Preparation For the best preservation of tissue morphology, the thickness of the tissue placed in fixative should be between 0.2 and 0.7 cm. Sections that are thicker require time for the fixative to permeate to the center, resulting in potential degradation. The volume of fixative should be at least 10 times that of the specimen. Fixation should be carried out as soon as possible after removal of the tissues, and for sufficient time to allow the permeation of the fixative into the tissue. Staff can provide the 10% buffered formalin by request. Tissues can remain in formalin for prolonged periods of time without compromising histology. However, after 24 hours, the longer the tissue is in formalin, the more antigenicity is lost.
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We believe that every researcher across the world should be able to connect with the thousands of global CROs that exist and have the opportunity to work together. Like many industries,the life science supply chain has been disrupted over the last year. But there are many other circumstances such as international customs regulations or sensitive shipping times that create limitations around which countries are feasible to partner with. Sometimes, finding a CRO based in a country that best suits your research needs is imperative. We hope this contract research map allows you to find the right partner in the right place at the right time.
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