Reset MapFreiburgstrasse 3 Bern, Bern, 3010 SwitzerlandAlveoliX AG is a Swiss biotechnology company headquartered in Bern, specializing in organ-on-chip technology. The company develops advanced in vitro models that replicate human organ functions for use in drug development and biomedical research. Its flagship product, the AX Lung-on-Chip system, mimics the microenvironment of the human lung, including natural breathing movements, using an ultra-thin, elastic membrane. This technology enables the creation of disease-specific and personalized models to test the safety and efficacy of drugs, pollutants, and cosmetics. AlveoliX aims to reduce the need for animal testing and improve the predictability of drug effects in early development stages. In recognition of its innovation, the company received the Swiss Medtech Award in 2022 for its organ-on-chip platform. AlveoliX operates across two sites, with its headquarters located in Bern and the fabrication in Biel. The facilities are equipped with a broad range of molecular biological read-out technologies, including sequencing, flow cytometry, and other advanced analytical tools. These capabilities support a wide array of research applications such as target identification, ADME (absorption, distribution, metabolism, and excretion), and pharmacodynamic (PD) studies. In addition to its core technology, AlveoliX offers services for compound lead optimization and preclinical studies using 2D cell cultures, organoids, and organs-on-chip platforms. The company also provides chemical risk and safety assessment, efficacy testing, and supplies its organs-on-chip systems along with complementary read-out equipment to enable high-quality, human-relevant in vitro research.
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