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Atlant Clinical

36 Yevhena Konovaltsia Street Kyiv, 01133 UkraineAtlant Clinical is a strong multinational contract research organization (CRO) offering a full range of clinical trials (Phases I-IV) and relevant support services throughout the US, Europe, Ukraine, Russia, and Middle Asia.

Bienta

78 Chervonotkatska Street Kyiv, Please Select, 02094 UkraineBienta is a trademark for preclinical biology services of Enamine, the world’s largest supplier of drug-like molecules for drug discovery research. Bienta is operating as a Contract Research Organisation providing biomolecular screening (HTS) services as well as comprehensive bioanalytical support of drug discovery projects, including in vitro ADMET (absorption, distribution, metabolism, excretion, toxicty) testing as well as pharmacokinetics (PK) and toxicity studies in animals.

BIOMEDICA CRO LLC

9-V Academician Glushkov Avenue, Suite 249 Kyiv, 03187 UkraineBIOMEDICA CRO is your global biospecimen partner since 2017. We collect human biospecimens through a broad network of partnered hospitals in Ukraine and supply them globally for pre-clinical studies. Despite Russian aggression, we work as usual. Located in safe places clinical sites are fully operational as well as our primary investigators are ready to make their contribution to the scientific cooperation. We guarantee the high quality of our samples, which is extremely important for us even in wartime. There are ways to ship samples all over the world (by car to the nearest counties and then by plane to the destination point). We provide: TISSUE SAMPLES Diseased & Normal Adjacent: fresh tissue, fresh frozen tissue, formalin-fixed paraffin-embedded (FFPE) blocks, histological slides BLOOD SAMPLES Various medical conditions & healthy donors: Fresh, Whole blood, Plasma, Double-spun plasma, Serum, Red cells, Buffy coat, Peripheral Blood Mononuclear Cells (PBMCs) OTHER BIOFLUIDS Various medical conditions & healthy donors: Sputum, Saliva, Aspirate, Swabs, Urine, Stool, Synovial fluid (SF), Cerebrospinal fluid (CSF), and others BIOMEDICA CRO manages its own network of 50+ direct contracts with hospitals in Ukraine in many therapeutic areas and ready to make a new one if necessary. We are able to support you and your scientists in a broad range of oncological conditions and therapeutic diseases which are included but not limited to the following list: allergology, autoimmune indications and conditions, benign conditions and normal controls, cardiology, dermatology, endocrinology, gastroenterology, gynecology and urology, hematology, infections (including COVID-19), lab testing remnants, neurology, ophthalmology, orthopedic, traumatology, ICU, pulmonology, reproductology, rheumatic disorders and many others. Our services facilitate the ease in your research in an efficient and effective manner. Once you have a need in pre-clinical trial, we are ready to provide a full support in line with good laboratory (GLP) and good clinical practice (GCP). We routinely collect hundreds of biospecimens for global studies and strengthen them with valuable and precise clinical data. We believe our motto “Quality is our DNA” is a key success factor to accelerate the precision medicine programs for oncology, therapeutics and infectious conditions. The BIOMEDICA CRO team has a unique combination of expertise and knowledge in the life sciences. The medical background of site managers guarantees that every project detail will be clearly communicated to primary investigators, while the scientific proficiency of lab and data managers secures a multi-step quality control. Being customer oriented, we tune our processes to be flexible and compliant to meet changing project requirements and ensure that we provide high-quality biospecimens on time and within a budget.

BIOMEDICA CRO LLC

132 Holosiivskyi avenue, Office 8, Floor 4 Kyiv, 03127 UkraineBIOMEDICA CRO is your global biospecimen partner since 2017. We collect human biospecimens through a broad network of partnered hospitals in Ukraine and supply them globally for pre-clinical studies. Despite Russian aggression, we work as usual. Located in safe places clinical sites are fully operational as well as our primary investigators are ready to make their contribution to the scientific cooperation. We guarantee the high quality of our samples, which is extremely important for us even in wartime. There are ways to ship samples all over the world (by car to the nearest counties and then by plane to the destination point). We provide: TISSUE SAMPLES Diseased & Normal Adjacent: fresh tissue, fresh frozen tissue, formalin-fixed paraffin-embedded (FFPE) blocks, histological slides BLOOD SAMPLES Various medical conditions & healthy donors: Fresh, Whole blood, Plasma, Double-spun plasma, Serum, Red cells, Buffy coat, Peripheral Blood Mononuclear Cells (PBMCs) OTHER BIOFLUIDS Various medical conditions & healthy donors: Sputum, Saliva, Aspirate, Swabs, Urine, Stool, Synovial fluid (SF), Cerebrospinal fluid (CSF), and others BIOMEDICA CRO manages its own network of 50+ direct contracts with hospitals in Ukraine in many therapeutic areas and ready to make a new one if necessary. We are able to support you and your scientists in a broad range of oncological conditions and therapeutic diseases which are included but not limited to the following list: allergology, autoimmune indications and conditions, benign conditions and normal controls, cardiology, dermatology, endocrinology, gastroenterology, gynecology and urology, hematology, infections (including COVID-19), lab testing remnants, neurology, ophthalmology, orthopedic, traumatology, ICU, pulmonology, reproductology, rheumatic disorders and many others. Our services facilitate the ease in your research in an efficient and effective manner. Once you have a need in pre-clinical trial, we are ready to provide a full support in line with good laboratory (GLP) and good clinical practice (GCP). We routinely collect hundreds of biospecimens for global studies and strengthen them with valuable and precise clinical data. We believe our motto “Quality is our DNA” is a key success factor to accelerate the precision medicine programs for oncology, therapeutics and infectious conditions. The BIOMEDICA CRO team has a unique combination of expertise and knowledge in the life sciences. The medical background of site managers guarantees that every project detail will be clearly communicated to primary investigators, while the scientific proficiency of lab and data managers secures a multi-step quality control. Being customer oriented, we tune our processes to be flexible and compliant to meet changing project requirements and ensure that we provide high-quality biospecimens on time and within a budget.

BIOMEDICA CRO LLC

132 Holosiivskyi avenue, Office 8, Floor 4 Kyiv, Kyiv, 03127 UkraineBIOMEDICA CRO is your global biospecimen partner since 2017. We collect human biospecimens through a broad network of partnered hospitals in Ukraine and supply them globally for pre-clinical studies. Despite Russian aggression, we work as usual. Located in safe places clinical sites are fully operational as well as our primary investigators are ready to make their contribution to the scientific cooperation. We guarantee the high quality of our samples, which is extremely important for us even in wartime. There are ways to ship samples all over the world (by car to the nearest counties and then by plane to the destination point). We provide: TISSUE SAMPLES Diseased & Normal Adjacent: fresh tissue, fresh frozen tissue, formalin-fixed paraffin-embedded (FFPE) blocks, histological slides BLOOD SAMPLES Various medical conditions & healthy donors: Fresh, Whole blood, Plasma, Double-spun plasma, Serum, Red cells, Buffy coat, Peripheral Blood Mononuclear Cells (PBMCs) OTHER BIOFLUIDS Various medical conditions & healthy donors: Sputum, Saliva, Aspirate, Swabs, Urine, Stool, Synovial fluid (SF), Cerebrospinal fluid (CSF), and others BIOMEDICA CRO manages its own network of 50+ direct contracts with hospitals in Ukraine in many therapeutic areas and ready to make a new one if necessary. We are able to support you and your scientists in a broad range of oncological conditions and therapeutic diseases which are included but not limited to the following list: allergology, autoimmune indications and conditions, benign conditions and normal controls, cardiology, dermatology, endocrinology, gastroenterology, gynecology and urology, hematology, infections (including COVID-19), lab testing remnants, neurology, ophthalmology, orthopedic, traumatology, ICU, pulmonology, reproductology, rheumatic disorders and many others. Our services facilitate the ease in your research in an efficient and effective manner. Once you have a need in pre-clinical trial, we are ready to provide a full support in line with good laboratory (GLP) and good clinical practice (GCP). We routinely collect hundreds of biospecimens for global studies and strengthen them with valuable and precise clinical data. We believe our motto “Quality is our DNA” is a key success factor to accelerate the precision medicine programs for oncology, therapeutics and infectious conditions. The BIOMEDICA CRO team has a unique combination of expertise and knowledge in the life sciences. The medical background of site managers guarantees that every project detail will be clearly communicated to primary investigators, while the scientific proficiency of lab and data managers secures a multi-step quality control. Being customer oriented, we tune our processes to be flexible and compliant to meet changing project requirements and ensure that we provide high-quality biospecimens on time and within a budget.

Cromos Pharma

35/58, Kyrovogradskaya str. Kyiv, 03069 UkraineCromos™ Pharma is a regional contract research organization (CRO) that specializes in biopharmaceutical clinical monitoring & outsourcing to Geоrgia, Belarus, Russia, Ukraine, Baltic States‎, countries of Eastern Europe and Israel. The company has been successfully managing Phase I-IV clinical trials, bioequivalence and observational studies since 2004. Our business model is a product of the most validated Western solutions which are carefully tailored to local environments. Cromos™ Pharma has a proven track record of rapid patient accrual and retention that often exceeds other geographies by a factor of 5. As project managers, our "summa cum laude" MDs and PhDs don't just flawlessly adhere to a study protocol, they appreciate the science behind it. By choosing Cromos™ Pharma you get an invariable guarantee that your project will be handled by the "A-team". In 2012 Cromos™ Pharma has adopted a fully integrated, cloud-based, virtual workplace model. This has allowed for seamless integration of all offices and employees, significantly increased the company's productivity and reduced its overhead. Cromos™ Pharma’s industry-leading proprietary CTMS further increases company’s internal efficiency and performance and empowers sponsors by providing them with real-time access to operational, administrative and financial information about their studies. Cromos™ Pharma's risk-sharing clinical development platform allows the sponsors to pay for performance and is our guarantee that the study timelines will be met. It also offers biotech, pharma and device companies with promising technologies several unique business partnership algorithms, including clinical research program conduct in exchange for equity or licensing opportunities. We invite interested pharmaceutical, biotech, and medical device companies to reach out to us for an in depth evaluation of potential strategic partnerships.

Curpys Chemicals

Teremkivska Street 2-A, office 1 Kyiv, 03187 UkraineCurpys Chemicals was founded in 2014 as a spin-off from Institute of Organic Chemistry NAS Ukraine (Kyiv). The company is a supplier of high-quality sophisticated building blocks for organic synthesis, drug discovery, biological studies, agrochemistry, material science and other areas of R&D in commercial entrprises and academic organizations across the globe. Our team consists of more than 30 qualified chemists with over 10 years' experience in synthetic organic chemistry. Broad skills in advanced chemistry practice including inconvenient and dangerous chemistry, in house elaborated synthetic methods, excellent knowledge of modern approaches in organic synthesis and keen understanding of drug discovery problems allows us to offer unique and rare compounds that ideally answer the needs of life science industries.

Clinical Trials Logistics

Skladska Str 40 69050 Zaporizhzhia UkraineClinical Trials Logistics is a specialist in the field of clinical trials logistics.

Life Chemicals

5 Murmanska Str., Kyiv, UkraineLife Chemicals Inc., founded in 2004 in Burlington, Ontario, Canada, is a major producer and supplier of HTS compounds and well recognized provider of custom synthesis and computational chemistry services to pharmaceutical, biotech, crop science companies and academic institutions across the globe. Developing its business development Life Chemicals has associated and headquartered a family of R&D chemical companies, namely I.F. Lab, Spoluka, Spectrum Info (Kyiv, Ukraine), Life Chemicals USA (Woodbridge, CT), and Life Chemicals Europe (Munich, Germany), to operate as an integral whole where every single company is focused on its individual range of products and services and, at the same time, all are motivated by achieving their common goal. Today Life Chemicals is a fully integrated platform for early drug discovery, providing complete range of contract research and contract manufacturing services. Our broad experience in synthetic organic chemistry and up-to-date equipment ensure high quality services in custom synthesis of drug-like compounds and advanced Building Blocks in mg to multiKG quantities, design and synthesis of combinatorial libraries, route scouting and production scale-up. Our expertise in computational chemistry and employment of versatile in silico techniques, such as similarity and pharmacophore search, molecular descriptors analysis, docking screening and protein modeling, enable careful design of Fragment collections, Targeted and Focused libraries and customized sets of compounds. Our keen understanding of drug discovery process with computer-assisted approaches, our knowledge of medicinal chemistry and our solid scientific background supported with a powerful production infrastructure allow us to provide efficient solutions for R&D programs of our customers, including hit-to-lead and lead optimization, improvement of drug potency, selectivity and ADMET, development of QSAR models and medchem design.

Enamine

78 Chervonotkatska Street Kyiv, 02000 UkraineEnamine offers screening libraries from its 2.6M collection, 170K building blocks and provides services in custom synthesis, discovery chemistry and lead optimization projects integrated with on-site biological screening and DMPK studies.

EGeen

25, Novomostitskaya Str., 04074, Kyev, UkraineEGeen provides clinical trials for the advancement of drug development for biotech and pharmaceutical clients.

FCH Group

PO Box 438 14017, Chernigiv UkraineFCH Group is a CRO providing custom synthesis in medicinal chemistry to pharmaceutical companies worldwide. With more than 30 PhD scientists conducting research and development, FCH Group offers a library of about 1,800,000 diverse drug-like small molecule compounds and about 3,000,000 advanced reagents for synthesis. Majority of reactive intermediates from our database are available in quantities of over 20 grams. If the requested compound is absent, we are ready to re-synthesize it as all these compounds were designed and obtained by our chemists. The customer will be provided with reliable information on the progress of the synthesis and estimated delivery date in this case. We provide free feedback on any proposed project, and are ready to sign a non-disclosure agreement prior to any discussions. Our research facilities are located in Chernigov, Ukraine with well developed infrastructure. We have 2 000 sq.ft of laboratory space equipped with 29 fume hoods. Our scientists are experienced in laboratory scale organic synthesis, drug and chemical product research, and chemical product sales. Particularly, our chemists have experience in catalysis, synthesis of heterocycles and amino acids, handling water- and air-reactive chemicals. We are flexible and responsive to customer needs to create additional value. Prompt response policy to customer inquiries, direct and open dialogue with customer are distinguished features of our company. We never stop improving the quality of our products and efficiency of the production processes. The leader of FCH Group Sergey Bova has over fifteen years experience in synthetic organic chemistry. He is a highly respected expert in the field of chemistry of heterocyclic compounds.

Global Clinical Trials

2/6 Novozabars’ka vul., office 316, Kiev, UkraineGCT provides project management, logistics, monitoring, and regulatory support.

Global Clinical Trials (GCT)

2/6 Novozabarska Street Office 316 Kyiv UkraineGlobal Clinical Trials (GCT) is a premium contract-research organization (CRO) that offers support for the preclinical and clinical Phase I-IV studies as well as post-marketing activities to Big Pharma, small and medium-sized biotech enterprises, groups and funds, as well as large universities and institutions. Headquartered in Princeton, USA, GCT offers both local and global support through 8 operational offices in Bulgaria, Czech Republic, Hungary, India, Poland, Romania, Russia, Slovakia, Ukraine, USA and is a founding partner of a network of reliable partners in Scandinavia and Western Europe. GCT team, that now consists of over 60 full-time clinical research professionals, gives individualized attention to each project and provides full range of services following the latest GCP, EMA and FDA guidelines at every stage of product development path. Our monitors and project managers are all certified clinicians experienced in GCP clinical research. Our experience, competent staff, close contact with the KOLs and the immense enrollment potential of the covered region ensure fast study start-up and compliance with the set timelines. GCT owns 400 sq.m. (4300 ft2) Drug Storage and Distribution facility in St. Petersburg, Russia. It is fully equipped, disaster protected and has multiple modes of storage (ambient, climate controlled, refrigerated, frozen). High standards of work and client satisfaction are proved by the fact that more than 80% of the business come from repeat clients. Meanwhile, in the recent years the number of our clients worldwide increased dramatically. We actively participate in specialized industry events worldwide. Since 2006 GCT is also an Exclusive Partner of “The White Nights” International ophthalmology congress in Russia.

Kinematica

Prosp. Akad. Palladina 44, Office 105 UA – 03680 Kyiv UkraineKinematica supplies instruments and machines in the field of dispersing technology for the laboratory, pilot plant and production applications.

LabConnect

1 Tymoschenko Street, Bldg 2, Office 4, 04212 Kiev, UkraineLabConnect is the preeminent provider of central laboratory support services for logistically and analytically complex studies. LabConnect offers clinical chemistry, DNA sequencing, nucleic acid extraction, genotyping, flow cytometry, pharmacology, and toxicology services.

NCube

13 Triokhsviatytelska Street Kyiv, 02000 UkraineNCube provides high-end software development services to companies worldwide. We offer strategic consulting, custom software development and dedicated team extension services.

OCT Clinical Trials

34 Lesi Ukrainki bul. suite 212, Kyiv, 01133 UkraineOCT Clinical Trials offers phase I-IV clinical research services such as clinical monitoring, clinical trials, preclinical studies, quality assurance, data management, and regulatory affairs. http://www.oct-clinicaltrials.com/

Otava Research and Development Company Ltd

1, Murmanska str, Kyiv-94, Ukraine, 02660Otava Research and Development Company Ltd, cooperating with leading Ukrainian research institutions, carries out research work in the format of outsourcing. The research team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for customers from all over the world. We offer research solutions in fields of medicinal chemistry and molecular biology. Whether you need to outsource a specific project, OtavaRD can provide you with quality and timely technical services. Molecular Modeling and Bioinformatics Services: • Gene and protein sequence analysis and alignment; • Homology modeling; • In silico protein modification analysis; • In silico ADME predictions; • In silico lead prediction; • In silico lead optimization; • In silico lead development; • Binding site identification and analysis; • Virtual screening; • Pharmacophore modeling; • Structure-activity relationship (SAR) analysis; • Computational studies of drug-receptor interactions; • Hit identification and optimization; • Protein variability analysis; • Protein secondary structure prediction; • Protein disorder region prediction; • Protein fold recognition; • Protein structure analysis; • Protein spatial structure quality evaluation; • Protein spatial structure correction; • Protein domain prediction; • Ab initio protein spatial structure prediction; • Protein molecular dynamics simulation; • Nucleic acid molecular dynamic simulation; • Molecular dynamic simulation of extra large heterogeneous systems; • Accurate binding energy prediction; • Analysis of differential gene expression (DGE); • Next generation sequencing analysis; • Gene expression clustering; • Kohonen’s maps; • Microarray data analysis; • DNA spatial structure prediction; • RNA spatial structure prediction; • Aptamer structure prediction; • Biomolecular contact surfaces prediction; • Systems network analysis. Chemical Services: • Collection of screening compounds (200,000+ compounds) and chemical building blocks (3,000+ compounds); • Synthesis of chemical building blocks; • Synthesis of combinatorial libraries based on chemical scaffold; • Custom synthesis of the biologically active compounds (inhibitors/activators, agonists/antagonists etc) on a stand-alone basis or as part of an integrated full service solution; • Synthesis route development and improvement; • Development of new multi-step synthesis pathways for the production of the complex molecules; • Hit-to-lead & lead optimization; • Cheminformatics, molecular modeling, virtual screening and QSAR in order to select/design compounds or target-focused libraries for various HTS screening and drug discovery projects. Molecular Biology Services: • Custom protein expression services; • Proteins affinity chromatography; • Transfection studies; • Lentivirus-mediated stable transfection; • Generation of stable cell lines; • Immunoblotting; • Immunostaining; • Immunoprecipitation; • qPCR; • Cytotoxicity screening; • Drugs testing assays; • Custom anti-sense oligos design; • Custom primers design.

Otava Research and Development Company Ltd

154 Zabolotnogo str, Kyiv, 03680, UkraineOtava Research and Development Company Ltd, cooperating with leading Ukrainian research institutions, carries out research work in the format of outsourcing. The research team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for customers from all over the world. We offer research solutions in fields of medicinal chemistry and molecular biology. Whether you need to outsource a specific project, OtavaRD can provide you with quality and timely technical services. Molecular Modeling and Bioinformatics Services: • Gene and protein sequence analysis and alignment; • Homology modeling; • In silico protein modification analysis; • In silico ADME predictions; • In silico lead prediction; • In silico lead optimization; • In silico lead development; • Binding site identification and analysis; • Virtual screening; • Pharmacophore modeling; • Structure-activity relationship (SAR) analysis; • Computational studies of drug-receptor interactions; • Hit identification and optimization; • Protein variability analysis; • Protein secondary structure prediction; • Protein disorder region prediction; • Protein fold recognition; • Protein structure analysis; • Protein spatial structure quality evaluation; • Protein spatial structure correction; • Protein domain prediction; • Ab initio protein spatial structure prediction; • Protein molecular dynamics simulation; • Nucleic acid molecular dynamic simulation; • Molecular dynamic simulation of extra large heterogeneous systems; • Accurate binding energy prediction; • Analysis of differential gene expression (DGE); • Next generation sequencing analysis; • Gene expression clustering; • Kohonen’s maps; • Microarray data analysis; • DNA spatial structure prediction; • RNA spatial structure prediction; • Aptamer structure prediction; • Biomolecular contact surfaces prediction; • Systems network analysis. Chemical Services: • Collection of screening compounds (200,000+ compounds) and chemical building blocks (3,000+ compounds); • Synthesis of chemical building blocks; • Synthesis of combinatorial libraries based on chemical scaffold; • Custom synthesis of the biologically active compounds (inhibitors/activators, agonists/antagonists etc) on a stand-alone basis or as part of an integrated full service solution; • Synthesis route development and improvement; • Development of new multi-step synthesis pathways for the production of the complex molecules; • Hit-to-lead & lead optimization; • Cheminformatics, molecular modeling, virtual screening and QSAR in order to select/design compounds or target-focused libraries for various HTS screening and drug discovery projects. Molecular Biology Services: • Custom protein expression services; • Proteins affinity chromatography; • Transfection studies; • Lentivirus-mediated stable transfection; • Generation of stable cell lines; • Immunoblotting; • Immunostaining; • Immunoprecipitation; • qPCR; • Cytotoxicity screening; • Drugs testing assays; • Custom anti-sense oligos design; • Custom primers design.

Otava Research and Development Company Ltd

150 Zabolotnogo Str., Kyiv, 03680, UKRAINEOtava Research and Development Company Ltd, cooperating with leading Ukrainian research institutions, carries out research work in the format of outsourcing. The research team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for customers from all over the world. We offer research solutions in fields of medicinal chemistry and molecular biology. Whether you need to outsource a specific project, OtavaRD can provide you with quality and timely technical services. Molecular Modeling and Bioinformatics Services: • Gene and protein sequence analysis and alignment; • Homology modeling; • In silico protein modification analysis; • In silico ADME predictions; • In silico lead prediction; • In silico lead optimization; • In silico lead development; • Binding site identification and analysis; • Virtual screening; • Pharmacophore modeling; • Structure-activity relationship (SAR) analysis; • Computational studies of drug-receptor interactions; • Hit identification and optimization; • Protein variability analysis; • Protein secondary structure prediction; • Protein disorder region prediction; • Protein fold recognition; • Protein structure analysis; • Protein spatial structure quality evaluation; • Protein spatial structure correction; • Protein domain prediction; • Ab initio protein spatial structure prediction; • Protein molecular dynamics simulation; • Nucleic acid molecular dynamic simulation; • Molecular dynamic simulation of extra large heterogeneous systems; • Accurate binding energy prediction; • Analysis of differential gene expression (DGE); • Next generation sequencing analysis; • Gene expression clustering; • Kohonen’s maps; • Microarray data analysis; • DNA spatial structure prediction; • RNA spatial structure prediction; • Aptamer structure prediction; • Biomolecular contact surfaces prediction; • Systems network analysis. Chemical Services: • Collection of screening compounds (200,000+ compounds) and chemical building blocks (3,000+ compounds); • Synthesis of chemical building blocks; • Synthesis of combinatorial libraries based on chemical scaffold; • Custom synthesis of the biologically active compounds (inhibitors/activators, agonists/antagonists etc) on a stand-alone basis or as part of an integrated full service solution; • Synthesis route development and improvement; • Development of new multi-step synthesis pathways for the production of the complex molecules; • Hit-to-lead & lead optimization; • Cheminformatics, molecular modeling, virtual screening and QSAR in order to select/design compounds or target-focused libraries for various HTS screening and drug discovery projects. Molecular Biology Services: • Custom protein expression services; • Proteins affinity chromatography; • Transfection studies; • Lentivirus-mediated stable transfection; • Generation of stable cell lines; • Immunoblotting; • Immunostaining; • Immunoprecipitation; • qPCR; • Cytotoxicity screening; • Drugs testing assays; • Custom anti-sense oligos design; • Custom primers design.

Otava Research and Development Company Ltd

150 Akademika Zabolotnoho Street Kyiv UkraineOtava Research and Development Company Ltd, cooperating with leading Ukrainian research institutions, carries out research work in the format of outsourcing. The research team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for customers from all over the world. We offer research solutions in fields of medicinal chemistry and molecular biology. Whether you need to outsource a specific project, OtavaRD can provide you with quality and timely technical services. Molecular Modeling and Bioinformatics Services: • Gene and protein sequence analysis and alignment; • Homology modeling; • In silico protein modification analysis; • In silico ADME predictions; • In silico lead prediction; • In silico lead optimization; • In silico lead development; • Binding site identification and analysis; • Virtual screening; • Pharmacophore modeling; • Structure-activity relationship (SAR) analysis; • Computational studies of drug-receptor interactions; • Hit identification and optimization; • Protein variability analysis; • Protein secondary structure prediction; • Protein disorder region prediction; • Protein fold recognition; • Protein structure analysis; • Protein spatial structure quality evaluation; • Protein spatial structure correction; • Protein domain prediction; • Ab initio protein spatial structure prediction; • Protein molecular dynamics simulation; • Nucleic acid molecular dynamic simulation; • Molecular dynamic simulation of extra large heterogeneous systems; • Accurate binding energy prediction; • Analysis of differential gene expression (DGE); • Next generation sequencing analysis; • Gene expression clustering; • Kohonen’s maps; • Microarray data analysis; • DNA spatial structure prediction; • RNA spatial structure prediction; • Aptamer structure prediction; • Biomolecular contact surfaces prediction; • Systems network analysis. Chemical Services: • Collection of screening compounds (200,000+ compounds) and chemical building blocks (3,000+ compounds); • Synthesis of chemical building blocks; • Synthesis of combinatorial libraries based on chemical scaffold; • Custom synthesis of the biologically active compounds (inhibitors/activators, agonists/antagonists etc) on a stand-alone basis or as part of an integrated full service solution; • Synthesis route development and improvement; • Development of new multi-step synthesis pathways for the production of the complex molecules; • Hit-to-lead & lead optimization; • Cheminformatics, molecular modeling, virtual screening and QSAR in order to select/design compounds or target-focused libraries for various HTS screening and drug discovery projects. Molecular Biology Services: • Custom protein expression services; • Proteins affinity chromatography; • Transfection studies; • Lentivirus-mediated stable transfection; • Generation of stable cell lines; • Immunoblotting; • Immunostaining; • Immunoprecipitation; • qPCR; • Cytotoxicity screening; • Drugs testing assays; • Custom anti-sense oligos design; • Custom primers design.

Pharmaxi

10A Akademika Filatova Street., Kyiv, Kyiv 01042, UAPharmaxi is innovative company introducing new technologies in project setting, data collection and monitoring of various clinical project for pharmaceutical industry. We successfully combine the experience and energy of experts in IT, project management, clinical databases, biostatistics and integrated services in the clinical trials governance. We provide the industry with know-how automated software systems for clinical trials conduction that dramatically improves the quality and timelines of projects. Our innovative approach to the organization and conduct of large-scale non-interventional studies and registries displays their level of evidence and quality to an entirely new orbit. Our extensive experience in clinical research and in the creation of integrated software solutions to satisfy the highest expectations of the customer.

Pharmaxi

Acad. Filatov Str., 10A office 3/20 Kiev, 01042 UkrainePharmaxi is innovative company introducing new technologies in project setting, data collection and monitoring of various clinical project for pharmaceutical industry. We successfully combine the experience and energy of experts in IT, project management, clinical databases, biostatistics and integrated services in the clinical trials governance. We provide the industry with know-how automated software systems for clinical trials conduction that dramatically improves the quality and timelines of projects. Our innovative approach to the organization and conduct of large-scale non-interventional studies and registries displays their level of evidence and quality to an entirely new orbit. Our extensive experience in clinical research and in the creation of integrated software solutions to satisfy the highest expectations of the customer.

Parexel

10 Shaumyana strParexel provides bioequivalence studies as well as clinical services across Phase I to Phase III of drug development including dose escalation, drug-drug interaction, biomarkers, first-in-man studies, ADME, imaging, and clinical research services.

Premier Research

Kiev 03115Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

Premier Research

Sevastopol Street, No. 13-17Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

PRA Health Sciences

ul. Sagaydachnogo 25 B.At PRA Health Sciences, providing innovative solutions for our clients is what we do. But innovation just for the sake of innovation isn’t why we do it. Side-by-side with our clients, we strive to move drug discovery forward, to help them develop life-saving and life- improving drugs. We help change people’s lives for the better every single day. It’s who we are. Innovating to help people is at the heart of our process, but it’s even more than that. It’s also our privilege.

PreciBio

Amosova, 9 Kyiv, Kyiv, 03068 UkrainePreci harnesses the complexity of a human disease and collects patient-specific data to asstist on the early stages of drug discovery. We work as a CRO and a Vendor which can acquire patient material on the large population scale and deliver it to researchers. We have also a wide portfolio of services, which includes: - tissue procurement from the network of hospitals - primary cell culture generation from donor tissue as 2D and 3D. - biomarker profiling, drug testing and NGS for oncology - oncology cell array production, which includes up to 50 patient-specific cancer cells, which describes the target population. - Drug-response profiling on arrays of primary cells. We believe that the future for oncology relies on the faithfulness of disease models. We work with clinical sites with flowless reputation in patient's safety and well-being according to all bioethics regulations. Contact us with your specific project requirements and we will take care of acquisition of the data with the best quality. Or contact us just to chat, both are wellcome!

Prime Bio Net

Kyiv, Ukraine Kyiv, 02096 UkrainePrime Bio Net - established in Ukraine private company operated as a provider of human biological samples for different research purposes. On an ongoing basis, we have access and ability to involve patients with various diseases in study research process with strict compliance of research`s criteria, in key medical areas, such as oncology, endocrinology, infectious, ophthalmology, dermatology, neurology and therapeutic in general. We focused on cooperation with Ukrainian research institutes, large state hospitals and their research departments, as well as private medical clinics. We and our partners are very interested in such research studies and their contribution to the future development of medicine and health care. High quality: Our staff is highly qualified and experienced in this field and as a result, we obtain high-quality biological samples, such as whole blood, plasma, serum, urine, tumor and normal tissue, stool and other. All samples are collected with strict conformity of GCP/ICH regulations, IRB (IEC), in accordance with the Protocol and SOPs. We believe that Ukrainian team will be able to satisfy most of your purposes.

SPRI Ukraine

15 Kuibysheva street, Kharkiv, Ukraine, 61050SPRI Ukraine offers clinical research services including project management, clinical trial monitoring, regulatory support, feasibility studies and quality assessment.

Spectrum Info

5, Murmanska str., 02094 Kiev, UkraineSpectrum Info offers fine chemicals, organic compounds, reference compounds, reagents, building blocks, intermediates and custom synthesis services.

Taras Shevchenko National University of Kyiv

60 Volodymyrska Street, Kyiv, , UATaras Shevchenko National University of Kyiv is today a classic university with a distinct research profile, and the leading contemporary academic and educational hub of Ukraine. With the independent Ukrainian nation arising, the University is facing new challenges and responsibilities. The academic experts of the future can be identified by a thorough professional knowledge and the ability to think creatively, with an understanding of the massive responsibility to be taken when working at the leading-edge of academic thought. Only a university with a long tradition of achievement and success both in teaching and in research could cope with such a mission. On 21 April 1994, Kyiv University was granted the status of "National" by Leonid Kravchuk, the President of Ukraine by Decree № 176/94, and on 25 November 1999 a further Decree, № 1496/99, of Leonid Kuchma, President of Ukraine at that time, significantly expanded the autonomous status of the university. Decree № 412/2008, of Viktor Yushchenko, then President of Ukraine, on 5 May 2008, further stipulated the conversion of the University to becoming the main principal educational and scientific centre of Ukraine for the education of academic and teaching staff with higher qualifications. Then on 29 July 2009 the Cabinet of Ministers of Ukraine with Regulation № 795 granted the University the status of being a self-governing and autonomous national research university, while providing increased funding for the future development of the university.

Wacker

Street Verkhnii Val 72 04655 Kiev UkraineWacker offers contract manufacturing, biologic analysis, and quality control/assurance services.