755 Queensway E, Unit 24 Mississauga, ON, L4Y 4C5 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

Toronto, ON CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

80 St. George Street Suite 615 Toronto, Ontario M5S 3H6 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

2395 Speakman Drive, Suite 2111 Mississauga, ON, L5K 1B3 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

2382 Dunwin Dr Mississauga, Ontario, L5L 1J9 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

121 Deloraine Ave Toronto, Ontario, M5M 2B1 CanadaACE is a one-stop shop for accessing academic health expertise and consulting services. We tackle a wide range of topics that impact on public and private sector health organizations, including (but not limited to) strategic planning, management and innovation; evidence-based practice/policy; value-based health care; program/policy implementation; health professions education and regulation; health economics; and health technology assessment.

Toronto, ON CanadaAccre Chemicals is a contract research organization of new drug discovery, pharmaceuticals, medicinal chemistry research, chemical libraries and custom chemical synthesis.

2640 Midland Avenue Toronto, Ontario M1S1R7 CanadaAccre Chemicals is a contract research organization of new drug discovery, pharmaceuticals, medicinal chemistry research, chemical libraries and custom chemical synthesis.

8 KING STREET EAST SUITE 107 TORONTO, ON, M5C 1B5 CanadaOur goal is to provide comprehensive and innovative industry-standard software solutions to our clients to help accelerate research and strengthen their competitive position.

700 Bay street, Suite 1100 Toronto Ontario M5G 1Z6 CanadaACGT offers DNA synthesis, DNA sequencing and DNA analysis services.

41 Bittern Street Ancaster, Ontario, L9G 4V5 CanadaActivation Laboratories offers protein testing, materials testing, chromatography, spectroscopy, biomarker discovery, and wet chemistry services.

41 Bittern Street Ancaster, ON, Canada L9G 4V5The Actlabs Group of Companies provides contract analytical services covering all aspects of analysis from academic research applications to routine quality control functions. We provide our services to many fields, including Agriculture, Geochemical, Petroleum, Industrial Minerals, Forensic, Pharmaceutical & Clinical, Environmental & Occupational Health and Materials Testing areas.

2801 Long Rd Grand Island, New York, 14072 1244 United StatesActylis is a global company offering sourcing and manufacturing solutions tailored to meet our clients’ diverse and evolving needs. With deep expertise in quality and regulatory compliance, sourcing and logistics management, analytical services, and R&D support, we reduce complexities and mitigate risks, empowering our partners to focus on growing their business. Our Manufacturing Sites Include: Eugene, OR, US: Premier full service CDMO site focused on clinical synthetic chemistry, late discovery through phase 2 clinic, with support for commercial manufacturing, RSMs, and impurity markers. Buffalo, NY, US: Actylis Buffalo performs complex multi-step synthesis to manufactures chemicals in kilogram to multiple ton quantities to serve client in a variety of industries. Montreal, QC, CA: Custom manufacturing of excipients, buffers and process solutions for our global client base has allowed Actylis Montreal to rapidly resolve our customers’ challenges in either the preclinical phase, in clinical trial phases I, II or III, or in commercial finished drug manufacturing. Ogden, UT, US: Discovery, development, and manufacture of chelated mineral products optimized for bioavailability and tolerability for nutraceutical use. Limerick, IE: Manufacturer of GMP biological buffers, process solutions, cleaning solutions, Water for Injection (WFI), chemical blends and custom liquid blends. Runcorn, UK: The facility specializes in the development & manufacture of fine chemicals into a range of industry sectors including: Pharmaceutical, Agrochemical, Aroma chemical, Specialty, Polymer, Electrical, and Coatings. Ahmedabad, GJ, IN: State-of-the-art manufacturing facility producing laboratory chemicals, pharmaceutical excipients and solvents, food grade additives, and aquaculture specialty products in GMP & nonGMP grades. Our Office and Warehouse Sites Include: Port Washington, NY, US Lyon, FR Dusseldorf, DE Amsterdam, NL Basel, CH Hamburg, DE Shanghai, CN Mumbai, IN Bangalore, IN Singapore, SG

610 University Avenue Room 9-715 Toronto, Ontario, M5G 2M9 CanadaAdela will provide an advanced blood test to detect multiple high-morbidity, high-mortality diseases before symptoms occur, and to enable management through the entire care continuum. Adela's ability to detect many diseases through a single platform with best-in-class performance sets it apart from other liquid biopsy companies.

110 Yonge Street, 14th floor, Toronto Ontario M5C 1T4 USAAdvanced Chemistry Development offers spectroscopy, chromatography, preformulation, chemical patenting, and medicinal chemistry.

380 Jamieson pkwy Unit 7&8 Cambridge, ON, N3C 4N4 CanadaAdvanced Electrophoresis Solutions Ltd (AES) is a market leader for protein charge variant separation and characterization. AES has been working with leading biopharmaceutical research & producers answering their diversely urgent needs. AES has been providing critical reagents including a wide range of carrier ampholytes and pI markers supplied for essential lot release quality control (QC) of commercial therapeutic proteins, which saves millions of dollars for our customers for potential product disruption, exploration of replaced QC method, or file applications for revalidating SOPs to the regulatory agency. AES’s essential product: CEinfinite system is the only platform for high throughput reliable analytical iCIEF and both online iCIEF-MS coupling and off-line preparative iCIEF to do cross-verification and jointly conduct comprehensive and in-depth research on charge isomers.

1600 Industrial Road Cambridge, ON, N3H 4W5 CanadaAdvanced Electrophoresis Solutions Ltd (AES) is a market leader for protein charge variant separation and characterization. AES has been working with leading biopharmaceutical research & producers answering their diversely urgent needs. AES has been providing critical reagents including a wide range of carrier ampholytes and pI markers supplied for essential lot release quality control (QC) of commercial therapeutic proteins, which saves millions of dollars for our customers for potential product disruption, exploration of replaced QC method, or file applications for revalidating SOPs to the regulatory agency. AES’s essential product: CEinfinite system is the only platform for high throughput reliable analytical iCIEF and both online iCIEF-MS coupling and off-line preparative iCIEF to do cross-verification and jointly conduct comprehensive and in-depth research on charge isomers.

1348 Sandhill Drive Hamilton, ON, L9G 4V5 CanadaAffinity Biologicals Inc. (Affinity) was founded in 1987 by the principals Hugh and Patricia Hoogendoorn. With a strong background in hemostasis research and a focus on reagent development, Affinity has become a primary manufacturer of more than 250 reagents and kits used in hemostasis and thrombosis research and diagnostics. Our product line includes: coagulation related antibodies, matched-pair antibody sets for ELISA, depleted/deficient plasmas, protease inhibitor deficient plasmas, the VisuLize™ line of complete ELISA kits and the VisuCon™ & VisuCal™ coagulation controls and calibration plasmas. All Affinity Biologicals products are manufactured in our Ancaster, ON (Canada) facility, products are sold direct in North America and world wide through a network of branded and private-label distributors.

101 College Street, Suite 335 Toronto Ontario M5G 1L7 CanadaAIM Therapeutics offers development of treatments for asthma, bronchitis, spinal injuries, diabetes, restenosis, and other inflammatory conditions.

316 Edgeley Blvd Concord, Ontario Canada, L4K 3Y3A&K Petrochem is one of the leading suppliers in the chemical distribution business across Canada and has represented many major manufacturers around the world since 1971.

Glencameron Road 81 Thornhill, Ontario L3T 1N8 CanadaAlanza is a manufacturer of products for the pharmaceutical, biopharmaceutical, and biotechnology industries.

30 Adelaide St E 12th Floor Toronto, Ontario, M5C 3G8 CanadaAlira Health is an international patient-centric and technology-enabled advisory firm whose mission is to humanize healthcare. We work with healthcare and life sciences organizations looking for support across their entire solutions lifecycle, from development to medical care, through real-world evidence. Our integrated and multidisciplinary team of over 700 scientists, strategists, economists, clinicians, and biostatisticians collaborate across our North American, European, and Asian offices and advise 80% of the top 50 of MedTech companies and 75% of the top 50 of Pharma companies.

4520 Dixie Road Mississauga ON L4W 1N2 CanadaAllied Research International provides clinical trials, early/late stage development, regulatory affairs, and bioanalytical techniques.

20 Cutten Place Guelph Ontario N1G 4Z7Founded in 1980 by Irish biochemist and entrepreneur Dr. Pearse Lyons, Alltech is a leading global biotechnology company whose mission is to improve the health and performance of people, animals and plants through natural nutrition and scientific innovation. We pursue this mission guided by what we call the ACE principle, our promise that in doing business we have a positive impact on the Animal, the Consumer and the Environment. Animal Health Our core business improves animal health and performance by adding nutritional value to feed, naturally, through Alltech’s innovative use of yeast fermentation, enzyme technology, algae and nutrigenomics, which studies the impact of nutrition at the genetic level. Our technologies and support programs enable farmers to realize greater efficiency, profitability and sustainability on their farms. Alltech Crop Science Our Alltech Crop Science division complements our animal nutrition business by focusing on improving the health of crops. Our technologies enable us to improve the productivity of the field, in terms of yield quality and quantity, and to enhance nutrition beginning with the soil and the seed. Human Health We believe scientific innovation in animal and crop sciences is part of a much more important story, that of human health. Healthier animals and crops, nurtured naturally through Alltech’s nutritional solutions, affect human well-being. For example, fruits, vegetables and animal proteins have become less nutrient-rich in the past half-century. From fish to oranges, you need to eat more today to get the same nutritional value. Our work within animal and crop sciences is restoring value and also exploring ways to naturally enrich foods through improving the animal diet or crop produced. For example, laying hens fed a diet rich in Alltech’s algae produce eggs enriched with DHA omega-3, an essential nutrient for human cognitive development and health at all ages.

110 Yonge Street toronto Toronto, ON, M5C 1T4 CanadaThe Amaris Health Economics and Market Access (HEMA) brings together people of diverse backgrounds and combines robust quantitative and qualitative methods in order to provide a range of solutions to our pharmaceutical, biotech and medical device clients. Amaris HEMA is a global team of over 70 consultants spread out in 8 different offices around the world (Europe, North America and APAC). Our activities cover three main practices areas: - Health Economics Modelling (Cost-Effectiveness, Budget Impact, Sequential Modelling, Dynamic Modelling etc.) at both the global and the local levels (model adaptations) - RWE and Biostatistics (Secondary database analysis, Primary data collection, MAIC, ITC, NMAs etc.) - Evidence, Value and Access (SLRs, TLRs, GVDs, Landscape assessments, Evidence generation plans, KOL interviews etc.) The three Amaris HEMA practice areas collaborate on evidence review/package projects such as HTA submissions, with extensive experience in Canada, UK, France etc. Our profound understanding of the pharmaceutical market and solid scientific background makes us a valuable and reliable partner along all phases of development. We have strong expertise in both very specific and technical projects. Amaris’ added value lies in the quality of its teams and their attention to detail, as well as in the way the company capitalizes on their knowhow. Every employee is encouraged to develop a proactive, efficiency-oriented working style in order to provide only the most innovative solutions. The Health Economics and Market Access (HEMA) department of Amaris is part of the Amaris Group (http://amaris.com/en), an independent consulting company specialized in technology and management. Founded in 2007 in Switzerland, Amaris now employs more than 6,500 people based in more than 65 offices in 45 countries. Amaris provides services with a strong added value in all business sectors through five business lines: - Business & Management consulting - Information Systems and Technologies - Engineering and High technology - Telecommunications - Life Sciences (including Amaris HEMA).

Toronto, ON, CanadaAmbit offers kinase profiling and assay development services.

100 King St Tour Deloitte, Suite 1500 Toronto, Ontario, M5X1A9 CanadaAnalysis Group has a global footprint of integrated health care research capabilities. Across offices in North America, Europe, and Asia, we leverage our distinguished network of advanced-degree consultants, affiliated experts, and key opinion leaders to carry out an extensive range of work that includes real-world data (RWD) and real-world evidence (RWE) studies, post-marketing safety and effectiveness studies, indirect treatment comparisons, patient-reported outcomes (PROs), systematic literature reviews (SLRs) and meta-analysis, and AI-aided data solutions. Our clients benefit from our highly qualified teams across the world, which have substantial knowledge of local data, laws, and regulations but are also able to leverage our entire firm’s depth of expertise and integrate it seamlessly with local resources. We have supported the approval, launch, and market acceptance of numerous life sciences innovations in the US, EU and individual European countries. We have also provided expert input and testimony to regulatory and health technology assessment (HTA) bodies.

Buffalo, NY United StatesAndroBioSys offers its proprietary angiogenesis assay and develops diagnostic tests to detect the presence of circulating prostate cancer precursor cells.

Elm and Carlton Streets Buffalo, NY 14263 USAAndroBioSys offers its proprietary angiogenesis assay and develops diagnostic tests to detect the presence of circulating prostate cancer precursor cells.

2355 Derry Road East,Unit #23,Mississauga, Ontario, Canada,L5S 1V6Anogen, trade name of Yes Biotech Laboratories, offers antibody detection, production, and conjugation services.

701 Ellicott Street Buffalo, NY, 14203 United StatesApplied Healthcare Research Management (AHRM) inc., is a full service CRO with a focus in Health Economics and Outcomes Research (HEOR). With access to RWD based on existing relationships with providers in Western New York, AHRM can generate HEOR models consistent with ICER scoping documents or simulations models as a place holder for when RCT or RWD becomes available.

610 University Ave, 7-624 Toronto, ON, Canada M5G 2M9Applied Molecular Profiling Laboratory offers cytomics, genomics, pharmcokinetic and xenograft services.

Toronto, ON CanadaApplied Molecular Profiling Laboratory offers cytomics, genomics, pharmcokinetic and xenograft services.

11B Nicholas Beaver Rd. RR3 Guelph, ON N1H 6H9, CanadaAquaTox Testing & Consulting offers toxicity testing, ligand modelling, metal speciation, and tests for biodegradability and microbial respiration.

22 McCurdy Road Guelph, ON N1G 4Z9 CanadaArking Pharma Scientific is a leading Active Pharmaceutical Ingredients (APIs) and intermediates manufacturing and services company.

37 Merganser Drive, Guelph ON, N1C 1E2, CanadaArthroteq is a small pre-clinical research and histology services provider with a focus on bone and joint disease, inflammation, and neuropathic pain. Our expertise and services include research study design; protocol development; validation studies; PK&PD studies; efficacy studies for osteoarthritis, osteoporosis, tendon/ligament repair, cartilage repair, and bone (spinal fusion, critical size defect, ectopic, etc.).

120 Carlton Street, Suite 408 Toronto, Ontario, Canada M5A 4K2Attix Pharmaceuticals offers supply of raw materials and specializes in the development and manufacturing of nutraceutical products.

100 King Street West Toronto, Ontario, M5X 1C9 CanadaAtuka provides contract research and consultancy services for the biopharmaceutical industry with world-leading expertise in Parkinson's disease and other neurological conditions. We combine cutting-edge pre-clinical rodent and primate efficacy testing including a comprehensive range of motor and non-motor assays (e.g. cognition and impulse control) with medicinal chemistry services, DMPK and in-vivo imaging in aiding the development of novel therapeutics and diagnostics.

60 Leonard Avenue Toronto, ON, M5T0S8 CanadaAtuka provides contract research and consultancy services for the biopharmaceutical industry with world-leading expertise in Parkinson's disease and other neurological conditions. We combine cutting-edge pre-clinical rodent and primate efficacy testing including a comprehensive range of motor and non-motor assays (e.g. cognition and impulse control) with medicinal chemistry services, DMPK and in-vivo imaging in aiding the development of novel therapeutics and diagnostics.

Princess Margaret Cancer Centre 610 University Ave, 11th floor Toronto, ON, M5G 2M9 CanadaAtuka provides contract research and consultancy services for the biopharmaceutical industry with world-leading expertise in Parkinson's disease and other neurological conditions. We combine cutting-edge pre-clinical rodent and primate efficacy testing including a comprehensive range of motor and non-motor assays (e.g. cognition and impulse control) with medicinal chemistry services, DMPK and in-vivo imaging in aiding the development of novel therapeutics and diagnostics.

101 College Street Suite 120 Toronto, ON, M5G 1L7 CanadaAtuka provides contract research and consultancy services for the biopharmaceutical industry with world-leading expertise in Parkinson's disease and other neurological conditions. We combine cutting-edge pre-clinical rodent and primate efficacy testing including a comprehensive range of motor and non-motor assays (e.g. cognition and impulse control) with medicinal chemistry services, DMPK and in-vivo imaging in aiding the development of novel therapeutics and diagnostics.

480 University Avenue Suite 910 Toronto Ontario M5G 1V2 CanadaAxela Biosensors offers a unique portfolio of next generation, commercial stage, multiplex tools that provide enhanced analysis of proteins, DNA and RNA.

12 Capen Hall Buffalo, New York 14260-1660, USAThe Balthasar Laboratory utilizes pharmacokinetic and pharmacodynamic modeling and simulation to guide the development of new immunotherapies for the treatment of autoimmunity and cancer.

Hamilton, ON CanadaBay Area Genetic Laboratory (BAGL) is a fully licensed and accredited Canadian testing facility which provides research and clinical genetic testing throughout North America.

565 Sanatorium Road, Suite 205B, Sir William Osler Building Hamilton, ON L9C 7N4 CanadaBay Area Genetic Laboratory (BAGL) is a fully licensed and accredited Canadian testing facility which provides research and clinical genetic testing throughout North America.

6790 Kitimat Road, Unit 4 Mississauga, Ontario L5N 5L9 CanadaBecquerel Laboratories offers elemental analysis using radioactivity to analyze radioactive and non-radioactive materials.

23 Woodlawn Road Toronto, ON L3P 7G7 CanadaAn Integrated Contract Chemistry Service Organisation Since 2010, Bellen Chemistry has been providing chemistry CRO/CDMO services as an integrated Contract Chemistry Service Organization. With years of accumulated technical advantages and experience in chemical synthesis of small molecule compounds, Bellen has built a one-stop-shop chemistry service platform, supporting big pharmas, biotech innovators and new drug development institutions for their research programs from discovery to commercial stage through comprehensive chemistry solutions. Our R&D, production, sales and operation team are based globally and at present, Bellen has nearly 1,000 employees worldwide, of which our technical team accounts for around 50%. Bellen is committed to continuing investing in innovation and state-of-the-art facilities to enable a one-stop-shop chemistry service platform, adding value to your project from library synthesis to API GMP manufactory. Our Key Services & Capabilities: - Key intermediates & RSMs (non-GMP & GMP) - cGMP APIs - Flow chemistry & Biocatalysis - Process development & optimisation - Process safety assessment - Early phase scale up - Late phase API & intermediates manufacturing - Solid Phase & Recrystallisation platforms (New for 2023) Watch our introductory video here: https://www.youtube.com/watch?v=6EoahD-c6WI

23 Woodlawn Road Toronto, ON, L3P 7G7 CanadaAn Integrated Contract Chemistry Service Organisation Since 2010, Bellen Chemistry has been providing chemistry CRO/CDMO services as an integrated Contract Chemistry Service Organization. With years of accumulated technical advantages and experience in chemical synthesis of small molecule compounds, Bellen has built a one-stop-shop chemistry service platform, supporting big pharmas, biotech innovators and new drug development institutions for their research programs from discovery to commercial stage through comprehensive chemistry solutions. Our R&D, production, sales and operation team are based globally and at present, Bellen has nearly 1,000 employees worldwide, of which our technical team accounts for around 50%. Bellen is committed to continuing investing in innovation and state-of-the-art facilities to enable a one-stop-shop chemistry service platform, adding value to your project from library synthesis to API GMP manufactory. Our Key Services & Capabilities: - Key intermediates & RSMs (non-GMP & GMP) - cGMP APIs - Flow chemistry & Biocatalysis - Process development & optimisation - Process safety assessment - Early phase scale up - Late phase API & intermediates manufacturing - Solid Phase & Recrystallisation platforms (New for 2023) Watch our introductory video here: https://www.youtube.com/watch?v=6EoahD-c6WI

100 College St., Suite 320, Toronto ON M5G1L5 CanadaBioAspect SERVICES conducts efficacy and proof-of-principle studies in cellular, transgenic Drosophila, and rodent models of to identify health benefits of pharmaceutical, biotechnology, and nutraceutical products. BioAspect PRODUCTS supplies products for life science research including kits and assays, antibodies, proteins, human primary cells, benchtop lab equipment and many more.

100 College St Suite 322 Toronto, ON, M5G1L5 United StatesBioAspect SERVICES conducts efficacy and proof-of-principle studies in cellular, transgenic Drosophila, and rodent models of to identify health benefits of pharmaceutical, biotechnology, and nutraceutical products. BioAspect PRODUCTS supplies products for life science research including kits and assays, antibodies, proteins, human primary cells, benchtop lab equipment and many more.

20 Konrad Cres. Markham, ON, L3R 8T4 BermudaSince 2004, BioBasic Inc has been a trusted partner in the life sciences industry for supporting scientific research and innovation. As a direct manufacturer, we offer a wide selection of high-quality materials, reagents and services such as DNA Sequencing, Gene Synthesis, Protein expression & Purification, Peptide Synthesis and Antibody Production. We also have the industrial capacity to provide corresponding services in bulk as well as under GMP standards for certain products. Our team of scientists are also dedicated to providing personalized services through long-term partnerships and collaborations. With commitment to quality and customer satisfaction, BioBasic Inc has the expertise and experience to help you advance your research quickly and efficiently to meet your project goals.

20 Konrad Crescent Markham, ON, L3R 8T4 CanadaSince 2004, BioBasic Inc has been a trusted partner in the life sciences industry for supporting scientific research and innovation. As a direct manufacturer, we offer a wide selection of high-quality materials, reagents and services such as DNA Sequencing, Gene Synthesis, Protein expression & Purification, Peptide Synthesis and Antibody Production. We also have the industrial capacity to provide corresponding services in bulk as well as under GMP standards for certain products. Our team of scientists are also dedicated to providing personalized services through long-term partnerships and collaborations. With commitment to quality and customer satisfaction, BioBasic Inc has the expertise and experience to help you advance your research quickly and efficiently to meet your project goals.

4160 Bailey Avenue United States Amherst, New York, 14226 United StatesSince 2004, BioBasic Inc has been a trusted partner in the life sciences industry for supporting scientific research and innovation. As a direct manufacturer, we offer a wide selection of high-quality materials, reagents and services such as DNA Sequencing, Gene Synthesis, Protein expression & Purification, Peptide Synthesis and Antibody Production. We also have the industrial capacity to provide corresponding services in bulk as well as under GMP standards for certain products. Our team of scientists are also dedicated to providing personalized services through long-term partnerships and collaborations. With commitment to quality and customer satisfaction, BioBasic Inc has the expertise and experience to help you advance your research quickly and efficiently to meet your project goals.

4160 Bailey Avenue United States Amherst, NY, 14226 United StatesSince 2004, BioBasic Inc has been a trusted partner in the life sciences industry for supporting scientific research and innovation. As a direct manufacturer, we offer a wide selection of high-quality materials, reagents and services such as DNA Sequencing, Gene Synthesis, Protein expression & Purification, Peptide Synthesis and Antibody Production. We also have the industrial capacity to provide corresponding services in bulk as well as under GMP standards for certain products. Our team of scientists are also dedicated to providing personalized services through long-term partnerships and collaborations. With commitment to quality and customer satisfaction, BioBasic Inc has the expertise and experience to help you advance your research quickly and efficiently to meet your project goals.

5180 Orbitor Drive Unit 101 Mississauga, Ontario, L5W 5L9 CanadaBioCache Lab Solutions Inc. (BioCache) provides secure management of archived cells / tissues, fluids, genetic and other organic materials. BioCache also offers high resolution scanning and data management services related to these priceless biospecimens. BioCache also provides CRO services such as animal model development, imaging and pre-clinical studies or run preclinical studies in mouse / large animal models quickly and efficiently. BioCache can leverage the hospitals’ world leading expertise to give clients access to clinical samples for a range of biomarker analyses, in-vivo/ ex-vivo models of disease, sequencing, single cell-omics or genetic engineered mouse models of disease. All of this is further supported by secure cloud data storage capacity and remote accessibility. https://www.biocache.com/research-services Available services include: Pathology, immunohistochemistry, multiplex fluorescence with image analysis Patient derived preclincal models CLIA Laboratory diagnostic development Live animal imaging studies Analytical chemistry and metabolic profiling Sequencing and single cell-omics Slide scanning, and data storage/remote viewing Genetic engineered mouse models of disease

Saint Catharines, ON CanadaBiolyse Pharma offers custom GMP aseptic sterile filling and produces Paclitaxel while conducting research and development of natural compounds for therapeutic applications.

59 Wellandvale rd. St. Catharines, Ontario L2S 3Y2 CanadaBiolyse Pharma offers custom GMP aseptic sterile filling and produces Paclitaxel while conducting research and development of natural compounds for therapeutic applications.

299 John Bowser Crescent Newmarket, Ontario L3Y 7N9 CanadaBiostatistiX offers solutions and platforms in support of profiling mechanism of actions of new chemical entities, biomarkers, and gene expression.

3580 Harlem Road, Suite 2 Cheektowaga NY 14215Biotrax Testing Laboratory Inc is committed to Excellence. Our professional standards are evident in everything we do. Our customers receive the highest level of customer service available in the industry! Founded in 1997, our mission has been to provide quality accurate results with the fastest turn-around time available.

3580 Harlem Road, Suite 2 Cheektowaga NY 14215Biotrax has been ensuring the safety of foods since 1997. Focused mainly on Microbiology and related sciences, we have built our reputation as a leader in Food Safety microbiology, and environmental testing. Biotrax Testing Laboratory Inc is committed to Excellence. Our professional standards are evident in everything we do. Our customers receive the highest level of customer service available in the industry! Founded in 1997, our mission has been to provide quality accurate results with the fastest turn-around time available.

73 High St. United States Buffalo, NY, 14203 United StatesBuffalo BioLabs, LLC. (BBL) is a preclinical CRO offering affordable research services as personalized intelligent solutions. We have minimized the administrative burdens that limit flexibility in some larger organizations and have oriented our operations toward maximizing customer convenience. One on one interactions with your PhD-level Project Director will provide assistance with project planning and study design for a personalized experience. They will be available throughout the process to answer questions, provide guidance, and give frequent study updates so you always know where your project stands. We are quick to schedule, quick to execute, and quick to provide results! Buffalo BioLabs offer services in the research areas of Drug Discovery, Safety, In Vivo Research, and Immunotherapy. Our specialized experience is concentrated in the fields of oncology, age-related diseases, radiation pathologies, immunological disorders and infectious diseases. Visit our website at www.BuffaloBioLabs.com for a complete list of services.

875 Ellicott Street Buffalo, NY, 14203 United StatesThe Research Ethics Consult Service welcomes requests for support. Such requests may come from researchers, research staff, the CTRC Research Navigators, and the IRBs.

100 High Street Buffalo, NY, 14203 United StatesBuffalo General Medical Center is proud to be part of the Kaleida Health system and a major teaching affiliate of the University at Buffalo School of Medicine and Biomedical Sciences. As a 457-bed acute care medical center located on the Buffalo Niagara Medical Campus in downtown Buffalo, NY, Buffalo General provides the latest treatment options, technology and expert physicians.

100 High Street Buffalo, NY , 14203 United StatesBuffalo General Medical Center is proud to be part of the Kaleida Health system and a major teaching affiliate of the University at Buffalo School of Medicine and Biomedical Sciences. As a 457-bed acute care medical center located on the Buffalo Niagara Medical Campus in downtown Buffalo, NY, Buffalo General provides the latest treatment options, technology and expert physicians.

500-1919 Minnesota Court Mississauga, Ontario, L5N 0C9 Canada

4141 Sladeview Crescent, Unit 10, Mississauga, ON L5L 5T1 Canada

6740 Campobello Rd., Mississauga, ON L5N 2L8

5715 Coopers Ave., Unit 5 Mississauga, ON L4Z 2C7 CanadaCacheSyn offers custom synthesis for specialty products as well as a wide-selection of catalog products.

Mississauga, ON CanadaCacheSyn offers custom synthesis for specialty products as well as a wide-selection of catalog products.

6980 Creditview Rd, Mississauga, ON, L5N 8E2 CanadaCaldic is recognized as Canada’s leading food ingredient supplier, distributing a wide range of raw materials for the food and personal care market and specializing in the manufacture of antioxidants, release agents, bakery concentrates, dough conditioners and vitamin and mineral enrichment blends.

Toronto, ON CanadaCanadian Custom Packaging Company (CCP) offers custom product manufacturing, innovative product development, flexible manufacturing, competitive pricing, and strong customer support.

333 Rimrock Road Toronto, Ontario M3J 3J9 CanadaCanadian Custom Packaging Company (CCP) offers custom product manufacturing, innovative product development, flexible manufacturing, competitive pricing, and strong customer support.

501 Deerhurst Drive, Suite 102, Burlington, On l7l 5T1Canadian SHIELD Ethics Review Board was formed to expedite research at private practices in Canada and the USA. The administrative staff of Canadian SHIELD has extensive experience both within the pharmaceutical industry and at the research site. The Board Administrator understands the needs of study sponsors based on more than 18 years of drug development experience and has implemented streamlined procedures to minimize the administrative burden to both the sponsor and the Investigator.

University Health Network - Toronto Western Hospital Division of Neurosurgery, 4W-423 399 Bathurst Street Toronto, Ontario M5T 2S8The Canadian Virtual Brain Tumour Bank (CVBTB) is a national brain tumour banking resource that serves to further clinical, molecular and translational research. Under sponsorship with Schering-Plough Canada and in association with the Canadian Brain Tumour Consortium (CBTC), the CVBTB was created to provide research and academic communities easier access to high quality samples across the country. An informative, user-friendly and easy-to-navigate website, the CVBTB links brain tumour sample holdings from established brain tumour banks in Canada. As a virtual bank, the CVBTB does not store actual brain tumour samples but rather acts as a central point of access allowing researchers to query specific brain tumour samples. Once queries are completed, the CVBTB helps to coordinate the delivery of samples between researchers and respective tumour banks. The CVBTB also acts as a brain tumour banking resource by providing assistance on standardized operating procedures on procedures such as tissue sample accrual, tissue sample storage, blood and lymphocyte processing and tissue sample delivery. Under the collaboration of neurooncologists, ethics advisors, neuropathologists and technicians, the CVBTB hopes to play a large role in furthering brain tumour research and to make an impact both on a national and global scale.

2851 Brighton Rd. Oakville, ON L6H 6C9 CANADACan-Am Instruments Ltd. is a Canadian distributor of industrial process controls and a leader in providing quality environmental and laboratory instrumentation. We are an ISO 9001:2008 certified company and have been serving our valuable clients for over 45 years. Our products include waste water samplers, open channel and closed pipe flow meters, magnetic flow meters, remote wireless communications, online water analyzers, viscometers, texture analyzers, tank level controls, alarm dialers, oil in water monitors and treatment equipment, gas detection systems and various other portable and online meters. We represent the following manufacturers: Brookfield Engineering Laboratories Inc, American Sigma (a div. of the Hach Company), Hach, Highland Tank (McTighe Separators), Barnett Engineering, Arjay Engineering, Enmet Canada, FMI, ACR, MJK, Barnant, Novasina, Telog, and others.

190 Harris St Rockwood, ON N0B 2K0CanBioPharma Consulting provides consultative support for nonclinical research, clinical pathology interpretation, and due diligence.

120 Carlton St. Suite 204 Toronto, ON, M5A 4K2 CanadaCanCog Technologies offers canine cognitive models, in vivo brain imaging, rodent neuropsychiatic models, human cognitive assessment, and neurobiological screens.

120 Carlton St -suite 204 Toronto Ontario M5A4K2 CanadaCanCog Technologies offers canine cognitive models, in vivo brain imaging, rodent neuropsychiatic models, human cognitive assessment, and neurobiological screens.

120 Carlton St. Suite 204 Toronto CanadaCanCog Technologies offers canine cognitive models, in vivo brain imaging, rodent neuropsychiatic models, human cognitive assessment, and neurobiological screens.

6800 Kitimat Rd, Unit 1 Mississauga, Ontario, L5N 5M1 CanadaCandoo Pharmatech Company Inc. is a research-based and innovation-driven biopharmaceutical company specializing in advanced drug delivery and development, focusing on differentiated, complex and difficult-to-formulate oral dosage forms for small molecules and macromolecules. The proprietary drug delivery platforms of Candoo technologies together with its North America quality management system and regulatory expertise enable the QbD-based, robust and cost-effective development of innovative and generic pharmaceuticals with targeted absorption profile, faster regulatory approval and earlier to market.

2001 Main Street Buffalo, NY, 14208 United StatesThe Institute for Autism Research (iar) is an interdisciplinary collaborative research center dedicated to understanding autism and related developmental disorders and enhancing the lives of those affected and their families. Researchers from diverse backgrounds work together to address critical questions involving causes, development, assessment, clinical treatment, and education. This research work has led to development of several new and effective treatments which are provided by the iar staff, our community partners and schools. Researchers at the iar are also dedicated to training the next generation of researchers and practitioners through advanced academic, research, and clinical and community-based experiences. To learn more, click on the iar Links in the left navigation.

2001 Main Street, Buffalo NY 14208-1517The Institute for Autism Research (iar) is an interdisciplinary collaborative research center dedicated to understanding autism and related developmental disorders and enhancing the lives of those affected and their families. Researchers from diverse backgrounds work together to address critical questions involving causes, development, assessment, clinical treatment, and education. This research work has led to development of several new and effective treatments which are provided by the iar staff, our community partners and schools. Researchers at the iar are also dedicated to training the next generation of researchers and practitioners through advanced academic, research, and clinical and community-based experiences. To learn more, click on the iar Links in the left navigation.

2001 Main Street Buffalo, NY, 14208 United StatesCanisius College affirms its strong commitment to the advancement of ethical thought as it pertains to mankind’s relationship with nature and the other species with which we share the planet. The Canisius College Institute for the Study of Human-Animal Relationships (ISHAR) is at the forefront of Human-Animal Studies, engaging Canisius students and members of our community in dialogs on pressing issues. ISHAR functions include: It coordinates synergy among the graduate level Master’s Program in Anthrozoology, the undergraduate Animal Behavior, Ecology, and Conservation major, and for three undergraduate minors (Anthrozoology, Animal Behavior, and Zoo Biology). Interdisciplinary coordination among the college’s animal-related programs and our Philosophy and Religious Studies programs. An Anthrozoology Speaker Series. Biannual Anthrozoology symposia. Advocacy of animal welfare and conservation via: The Canisius Ambassadors for Conservation The Canisius Zoological Society Volunteers and Interns

2001 Main Street, Buffalo NY 14208-1517Canisius College affirms its strong commitment to the advancement of ethical thought as it pertains to mankind’s relationship with nature and the other species with which we share the planet. The Canisius College Institute for the Study of Human-Animal Relationships (ISHAR) is at the forefront of Human-Animal Studies, engaging Canisius students and members of our community in dialogs on pressing issues. ISHAR functions include: It coordinates synergy among the graduate level Master’s Program in Anthrozoology, the undergraduate Animal Behavior, Ecology, and Conservation major, and for three undergraduate minors (Anthrozoology, Animal Behavior, and Zoo Biology). Interdisciplinary coordination among the college’s animal-related programs and our Philosophy and Religious Studies programs. An Anthrozoology Speaker Series. Biannual Anthrozoology symposia. Advocacy of animal welfare and conservation via: The Canisius Ambassadors for Conservation The Canisius Zoological Society Volunteers and Interns

262 The Queensway N. RR#1, Keswick, ON L4P 3C8Carter Pharmaceutical Consulting provides solid oral dosage form development, manufacturing, consulting, process optimization, and training.

Toronto, ON, Canada,CellaVision offers analyzers, review software, competency software, and blood smearing devices.

10 Nugent Road Surrey Research Park Guidford, Surrey, GU2 7AF United KingdomCelLBxHealth (formerly ANGLE) is a world-leading liquid biopsy company with innovative circulating tumour cell (CTC) diagnostic solutions for use in research, drug development and clinical oncology using a simple blood sample. CelLBxHealth's FDA cleared and patent protected circulating tumour cell (CTC) harvesting technology known as the Parsortix® PC1 System enables complete downstream analysis of the sample including whole cell imaging and proteomic analysis and full genomic and transcriptomic molecular analysis.

700 Ellicott Street, Buffalo, NY 14203-1102Center for High-Throughput Structural Biology offers high throughput screening services.

Buffalo, NY United StatesCenter for High-Throughput Structural Biology offers high throughput screening services.

Toronto Medical Discovery Tower 9th Floor Rm 9-305 101 College Street Toronto, Ontario, Canada M5G 1L7Center for High-Throughput Structural Biology offers high throughput screening services.

250 College St Toronto, , ON , M5T 1L8 CanadaThe Centre for Addiction and Mental Health (CAMH) is the leading mental health and addictions research facility in Canada, and one of the largest in the world. Research at CAMH is an integrated part of the organization. We share CAMH’s vision, mission, and values. Our research program includes: • The Campbell Family Mental Health Research Institute, with a focus on brain science • Clinical research • The Institute for Mental Health Policy Research Affiliations As a teaching hospital, all CAMH scientists hold cross-appointments with the University of Toronto. CAMH is a designated WHO/PAHO Collaborating Centre in Addictions and Mental Health.

250 College St Toronto, , ON, M5T 1L8 CanadaThe Centre for Addiction and Mental Health (CAMH) is the leading mental health and addictions research facility in Canada, and one of the largest in the world. Research at CAMH is an integrated part of the organization. We share CAMH’s vision, mission, and values. Our research program includes: • The Campbell Family Mental Health Research Institute, with a focus on brain science • Clinical research • The Institute for Mental Health Policy Research Affiliations As a teaching hospital, all CAMH scientists hold cross-appointments with the University of Toronto. CAMH is a designated WHO/PAHO Collaborating Centre in Addictions and Mental Health.

Toronto, ON CanadaCENTUVA provides efficient and cost-effective MD and PhD contract services right across the industry. Our experienced team of MDs and PhDs work with Marketing/Sales and Medical Affairs departments across North America and Europe. We work on demand with pharmaceutical, medical device and medical diagnostics companies through a personalized approach. We offer several services including our award-winning Doctors Speaking With Doctors. See our service offer at www.centuva.com. Centuva’s unparalleled access to the medical community, expertise, value and credibility lets you target your markets, build ongoing dialogue and achieve your goals.

1416 Sweet Home Road Buffalo, NY, 14228 United StatesCH3 BioSystems is a biotechnology company based on an entirely new patent-protected chemical technology designed to identify and commercialize drug and diagnostic candidates.

Mississauga Ontario 52 CanadaChemi Pharmaceutical offers quality control testing, natural health products, stability studies, and method development.

230 Cranbrook Cres Kleinburg, Ontario, L4H 4K9 CanadaIndividual Consultant

150 King St W Suite 1503 Toronto, Ontario, M5H 4B6 CanadaClarivate is a leading global provider of transformative intelligence, including Cortellis and Decision Resources Group ("DRG"). We offer enriched data, insights & analytics, workflow solutions and expert services in the areas of Academia & Government, Intellectual Property and Life Sciences & Healthcare. For more information, please visit clarivate.com

1980 Matheson Boulevard East Suite A Mississauga, Ontario L4W 5N3 CANADAClearstone Central Laboratories offers laboratory testing for clinical trials.

73 High Street Buffalo, NY, 14203 United States

Richmond Hill, ON CanadaClinetica provides program management, study design, vendor selection, clinical monitoring, and protocol development.

Clinetica Biosciences International, Inc. 95 Mural Street, Suite 600 Richmond Hill, ON L4B 3G2Clinetica provides program management, study design, vendor selection, clinical monitoring, and protocol development.

600 University Ave., Room 6-423 Toronto, ON M5G 1X5 CanadaClinical Genomics Centre provides a broad range of services from upstream study design and grant writing support through to downstream data analysis including genomic analysis, NGS, and bioinformatics.

416 North Service Road East, Level 2 Oakville, ON L6H 5R2 CanadaCMX Research offers clinical research services including trial management, data management, patient recruitment, and regulatory submissions with expertise in urology and oncology studies.

Oakville, ON CanadaCMX Research offers clinical research services including trial management, data management, patient recruitment, and regulatory submissions with expertise in urology and oncology studies.

220 Yonge Street Suite 211 Toronto, ON, M5B 2L7 CanadaCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

7398 Yonge St Thornhill, Ontario, L4J 8J2 CanadaConcinto is a Canadian consulting firm with global experience focused on education, R&D, and commercialization in life sciences. We founded Concinto to present a new approach toward education and commercialization. We believe that the education and commercialization practices should be designed and delivered based on new drivers in the healthcare ecosystem. At Concinto, we design evidence-based strategies to pinpoint business opportunities and efficiently deliver relevant services and communications. We also utilize our clinical research and product development expertise to introduce novel products in targeted therapeutic areas to address unmet needs. We help our clients to optimize their operations and services for the new digital economy. Concinto offers new commercialization strategies and online education and communications to keep companies competitive in this new environment. Concinto is an accredited continuing education provider by the Canadian Council on Continuing Education in Pharmacy (CCCEP).

456 Sheppard Ave Pickering ON L1V 1E5 CanadaCorsidus provides ADME assays, toxicology, animal imaging, GLP drug preparation, radiolabeling, and spectrometry.

Buffalo, NY, USACPL-Contract Pharmaceuticals offers method development, validation, chromatography, spectrophotometry, microbial testing, and stability studies.

7600 Danbro Cres Mississauga Ontario L5N 6L6 CanadaCPL-Contract Pharmaceuticals offers method development, validation, chromatography, spectrophotometry, microbial testing, and stability studies.

2255 Sheppard Avenue East, Toronto, ON M2J, CACrossey Engineering Ltd. is a multi-disciplined consulting engineering firm that has been in existence since 1963. Our head office is located at 2255 Sheppard Avenue East in Toronto, Ontario. We also have branch offices in Ottawa. CEL is dedicated to ensuring that buildings function efficiently – over the short and long-term – while working within the clients’ budgets, timetables and aesthetic visions. CEL consistently helps clients achieve this by creating and adapting designs in the areas of Electrical, Mechanical, Telecommunications Infrastructure and Controls. We also provide Lighting (Consullux), Sustainability design (CEL Gruen) and Commissioning Services (VSC Group).

2255 Sheppard Ave. East Suite E—331 Toronto, Ontario, M2J 4Y1 CanadaCrossey Engineering Ltd. is a multi-disciplined consulting engineering firm that has been in existence since 1963. Our head office is located at 2255 Sheppard Avenue East in Toronto, Ontario. We also have branch offices in Ottawa. CEL is dedicated to ensuring that buildings function efficiently – over the short and long-term – while working within the clients’ budgets, timetables and aesthetic visions. CEL consistently helps clients achieve this by creating and adapting designs in the areas of Electrical, Mechanical, Telecommunications Infrastructure and Controls. We also provide Lighting (Consullux), Sustainability design (CEL Gruen) and Commissioning Services (VSC Group).

The Conventus Building 1001 Main Street Buffalo, NY, 14203 United StatesCuria is a global contract research, development and manufacturing organization (CDMO), offering products and services across the drug development spectrum to help our partners turn their ideas into real-world impact. We partner closely with pharmaceutical and biotechnology companies to boost business performance and improve patients’ lives. From early discovery and development through manufacturing and commercialization, our suite of custom solutions allows us to tailor every engagement to your precise needs, whether that’s an independent project or an opportunity that cuts across the drug continuum. Our capabilities are always growing, driven by our talented, experienced team and continued investment in cutting-edge technologies. We take great pride in a track record that stands among the best in the industry. No matter what we’re working on, you can trust Curia to deliver every solution to the highest standard—the direct result of unmatched expertise and decades of experience completing projects just like yours.

2585 Meadowpine Blvd. Mississauga, ON L5N 8H9Custom Biologics is Canada’s leading large molecule CRO providing custom bioassay design, validation and regulatory compliant testing. For over 10 years Custom Biologics has been designing, validating and implementing bioanalytical, ligand-binding, residual contamination and cell-based bioassays to support pre-clinical and clinical testing requirements of large and small molecules. We have extensive expertise in characterizing the functional properties of biologics, in particular biosimilars, as per ICH Q6B guidelines. A list of some of the biosimilars and supporting assays we are experienced with can be found here, http://custombiologics.com/biologics/biosimilars/ All work adheres to an exacting Quality Control System based on FDA 21 CFR, Parts 11 and 58 Guidelines.

Mississauga, ON, CanadaCustom Biologics is Canada’s leading large molecule CRO providing custom bioassay design, validation and regulatory compliant testing. For over 10 years Custom Biologics has been designing, validating and implementing bioanalytical, ligand-binding, residual contamination and cell-based bioassays to support pre-clinical and clinical testing requirements of large and small molecules. We have extensive expertise in characterizing the functional properties of biologics, in particular biosimilars, as per ICH Q6B guidelines. A list of some of the biosimilars and supporting assays we are experienced with can be found here, http://custombiologics.com/biologics/biosimilars/ All work adheres to an exacting Quality Control System based on FDA 21 CFR, Parts 11 and 58 Guidelines.

115 Skyway Ave Toronto, Ontario, M9W4Z4 CanadaCustom Biologics is Canada’s leading large molecule CRO providing custom bioassay design, validation and regulatory compliant testing. For over 10 years Custom Biologics has been designing, validating and implementing bioanalytical, ligand-binding, residual contamination and cell-based bioassays to support pre-clinical and clinical testing requirements of large and small molecules. We have extensive expertise in characterizing the functional properties of biologics, in particular biosimilars, as per ICH Q6B guidelines. A list of some of the biosimilars and supporting assays we are experienced with can be found here, http://custombiologics.com/biologics/biosimilars/ All work adheres to an exacting Quality Control System based on FDA 21 CFR, Parts 11 and 58 Guidelines.

207 Queens Quay West Suite 420 Toronto, Ontario, M5J 1A7 CanadaCyclica is a Toronto-based, globally recognized biotechnology company that leverages artificial intelligence and computational biophysics to reshape the drug discovery process. Cyclica's proprietary structure-based and AI-augmented drug discovery platform includes Ligand Design for multi-targeted and multi-objective drug design, and Ligand Express for off-target profiling, systems biology linkages, and structural pharmacogenomic insights. Taken together Ligand Design and Ligand Express design advanced lead-like molecules that minimize unwanted off-target effects, while providing a holistic understanding of a molecule's activity through integrated systems biology and structural pharmacogenomics. All taken together, Ligand Design and Ligand Express offer a powerful end to end AI-augmented drug discovery platform for the design of advanced, chemically novel lead-like molecules that simultaneously prioritizes compounds based on their polypharmacological profile, effectively minimizing undesirable off-target effects. Our differentiated platform opens new opportunities for drug discovery, including multi-targeted and multi-objective drug design, lead optimization, ADMET-property prediction, target deconvolution, and drug repurposing. By doing more with artificial intelligence, Cyclica aims to revolutionize a system troubled with attrition and costly failures, accelerate the drug discovery process, and develop medicines with greater precision.

5295 John Lucas Drive Burlington, ON, L7L 6A8 CanadaNatrix Separations is a leading supplier of high performance, single use and multi-cycle disposable chromatography products to the life science, food, beverage and water markets.

919 Fraser Drive Unit 11 Burlington, ON, L7L 4X8 CanadaCytodiagnostics supplies reagents and secondary antibodies while offering custom conjugation services for nanoparticles and dyes.

134 Ner Israel Drive Vaughan, ON, L4J 9L1 Canada

200 Elizabeth St Toronto, ON, M5G 2C4 Canada

200 Elizabeth Street Toronto, ON, M5G 2C4 Canada

2820 Argentia Road Suite 8-9 Mississauga, ON, L4G 8H9 CanadaDalriada’s Turn-Key Drug Discovery model is specifically designed to provide ultimate support for semi-virtual lean biotechs developing small molecule therapies. We uniquely integrate internal R&D, end-to-end program management, business and IP support to unlock the most rapid and agile program execution and ultimately the fastest route to the clinic. ​ We focus on value building for each client and partner and conduct all programs with an R&D-to-milestone approach. Drawing experience from Pharma, Biotech, VC, and Academia, Dalriada’s team equally understands both the science and business needs, which allows for a seamless collaboration with the biotech client or a fully autonomous project execution.

349 Wildcat Rd North York, ON, M3J 2S3 CanadaDalton Pharma Services, part of Seikagaku Corporation- Tokyo, Japan, is a leading cGMP Manufacturing Facility, providing integrated drug discovery services as well as pharmaceutical development and manufacturing services to the pharmaceutical and biotechnology industries. We are FDA Inspected and Health Canada approved and bring over 35 years of experience to every project. We can accelerate your Drug Discovery and Development Program by integrating process development, API manufacturing, and finish dose manufacturing all at a single location. We provide a full range of services from Discovery and Development to Manufacturing: cGMP Sterile Filling Services cGMP API Manufacturing Services API Process Development Formulation Development Services Custom Synthesis Flow Chemistry Conjugation Custom Peptide Synthesis cGMP Oligonucleotide Fill Contract Analytical Services Contract Research Services Medicinal Chemistry Services Polymorphic Screening Project Management

7 St. Thomas Street Suite 603 Toronto, Ontario, M5S 2B7 Canadadicentra is a full-service CRO serving the nutraceutical, dietary supplement, and functional food industries. Our research facility and welcoming clinic are located in Yorkville, downtown Toronto giving us unparalleled access to a large and diverse pool of research populations. Since our inception in 2002, we have completed over 18,000 projects and serviced over 1,200 companies internationally.

470 Coronation Drive, Toronto, Ontario, M1E 4Y4, CanadaDigital Specialty Chemicals is a fine-chemicals manufacturer, specializing in organophosphorus and organometallic chemistry. Since 1987, we have supplied custom and stock chemicals to pharmaceutical, semiconductor and specialty chemical markets worldwide. At Digital Specialty Chemicals (DSC), we have built our business on the firm belief that success lies with our people, the processes we deploy in chemical manufacturing and the investment we have made in our facility and people.

470 Coronation Drive Toronto, ON, M1E 4Y4 CanadaDigital Specialty Chemicals is a fine-chemicals manufacturer, specializing in organophosphorus and organometallic chemistry. Since 1987, we have supplied custom and stock chemicals to pharmaceutical, semiconductor and specialty chemical markets worldwide. At Digital Specialty Chemicals (DSC), we have built our business on the firm belief that success lies with our people, the processes we deploy in chemical manufacturing and the investment we have made in our facility and people.

1620 Tech Avenue Unit 3 Mississauga, ON L4W 5P4 CanadaDiteba Research Laboratories offers laboratory testing services including assay development and validation, quality control release testing, bioanalytical testing services, bioassays and feasibility testing.

Oakville, ON Canadadsa consultants provides regulatory affair services for drugs, medical devices, natural health products and cosmetics.

6800 Campobello Road Mississauga Ontario Canada L5N 2L8EBPI Environmental Bio-Detection Products offers Ames testing, genotoxicity testing, mutation analysis products and services.

4200 S Service Road Burlington, Ontario, L7L 4X5 CanadaElarex is a Canadian healthcare technology company commercializing its proprietary PT120 formulation technology which has proven to stabilize biologicals (including live vaccines!) so that they are as effective when stored at 40C as if they had been stored at -80C.

2395 Speakman Drive Mississauga, ON, L5K 1B3 CanadaElement’s Health Sciences Division offers consulting and analytical testing solutions for the pharmaceutical, medical device and biotech industries. Our facilities operate under GLP/GMP. We provide a wide range of CMC development services and clinical manufacturing (Phase I & II) for IND/NDA/ANDA drug products, specializing in parenteral, topical and ophthalmic products. We have an established expertise in method development & validation, harmonized compendia testing, E&L programs for manufacturing equipment, transdermal, inhalation, injectable, and combination medical device products. Our goal is to offer comprehensive solutions tailored for successful product approvals. Our relationships are built on expertise, partnerships and trust.

98 Walker Drive Brampton, ON, L6T 4H6 Canada

Empire Genomics 700 Michigan Avenue Suite 200 Buffalo, NY, 14203 United StatesEmpire Genomics offers Clinical Reference Lab Testing Services, Microarray Services, BAC clones, FISH probes, and Custom Arrays; also, qPCR and Next Gen Sequencing (NGS).

700 Michigan Avenue Suite 200 Buffalo, NY 14203Empire Genomics offers Clinical Reference Lab Testing Services, Microarray Services, BAC clones, FISH probes, and Custom Arrays; also, qPCR and Next Gen Sequencing (NGS).

701 Ellicott Street Buffalo, NY, 14203 United StatesEnhanced Pharmacodynamics, LLC (ePD) is a service provider which assists clients with the design and implementation of model-informed drug development strategies in oncology and other therapeutic areas. ePD leverages the knowledge derived from the application of advanced pharmacometric and cutting-edge systems pharmacology techniques to guide dose selection and provide timely decision-making results that have a fundamental impact on drug development programs. ePD works with venture-start-ups, mid-size biotech companies and large pharma in all stages of drug development.

6 Clark St. St. Catharines, Ontario L2R5G2 CanadaEntomogen offers environmental consulting, insect identification, tick identification, and viral testing for mosquito and tick borne diseases.

2395 Speakman Drive, suite 2001 Mississauga, Ontario, L5K1B3 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, provides integrated outsourcing solutions for drug substance / API, drug product, biologics and phytocannabinoids as a campus style facility based in North America. Specializing in complex and niche small molecule drug substance and drug product services, including high potent capabilities, we provide support from preclinical to commercial development & manufacturing. In biologics, our expertise lies in the development and scaling of monoclonal antibodies (mAbs) and other mammalian-based therapeutic proteins. Our offerings include upstream & downstream development, analytical services, antibody drug conjugate (ADC) capabilities, and scale-up capacity to 200L for pre-clinical and phase I supply. Additionally, we specialize in producing pharmaceutical-grade, high-quality phytocannabinoids via synthetic routes and reference standards. Core Services: Route Scouting Route synthesis Flow chemistry High Potent Development & Manufacturing Solid State R&D Pre-formulation and Formulation Development Fast Track Programs Upstream & Downstream Processing Development mAbs, ADCs Development

2240 Speakman Drive Mississauga, Ontario, L5K 1A9 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, provides integrated outsourcing solutions for drug substance / API, drug product, biologics and phytocannabinoids as a campus style facility based in North America. Specializing in complex and niche small molecule drug substance and drug product services, including high potent capabilities, we provide support from preclinical to commercial development & manufacturing. In biologics, our expertise lies in the development and scaling of monoclonal antibodies (mAbs) and other mammalian-based therapeutic proteins. Our offerings include upstream & downstream development, analytical services, antibody drug conjugate (ADC) capabilities, and scale-up capacity to 200L for pre-clinical and phase I supply. Additionally, we specialize in producing pharmaceutical-grade, high-quality phytocannabinoids via synthetic routes and reference standards. Core Services: Route Scouting Route synthesis Flow chemistry High Potent Development & Manufacturing Solid State R&D Pre-formulation and Formulation Development Fast Track Programs Upstream & Downstream Processing Development mAbs, ADCs Development

2884 Portland Drive Oakville, ON , L6H 5W8 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, provides integrated outsourcing solutions for drug substance / API, drug product, biologics and phytocannabinoids as a campus style facility based in North America. Specializing in complex and niche small molecule drug substance and drug product services, including high potent capabilities, we provide support from preclinical to commercial development & manufacturing. In biologics, our expertise lies in the development and scaling of monoclonal antibodies (mAbs) and other mammalian-based therapeutic proteins. Our offerings include upstream & downstream development, analytical services, antibody drug conjugate (ADC) capabilities, and scale-up capacity to 200L for pre-clinical and phase I supply. Additionally, we specialize in producing pharmaceutical-grade, high-quality phytocannabinoids via synthetic routes and reference standards. Core Services: Route Scouting Route synthesis Flow chemistry High Potent Development & Manufacturing Solid State R&D Pre-formulation and Formulation Development Fast Track Programs Upstream & Downstream Processing Development mAbs, ADCs Development

2884 Portland Drive Oakville, ON, L6H 5W8 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, provides integrated outsourcing solutions for drug substance / API, drug product, biologics and phytocannabinoids as a campus style facility based in North America. Specializing in complex and niche small molecule drug substance and drug product services, including high potent capabilities, we provide support from preclinical to commercial development & manufacturing. In biologics, our expertise lies in the development and scaling of monoclonal antibodies (mAbs) and other mammalian-based therapeutic proteins. Our offerings include upstream & downstream development, analytical services, antibody drug conjugate (ADC) capabilities, and scale-up capacity to 200L for pre-clinical and phase I supply. Additionally, we specialize in producing pharmaceutical-grade, high-quality phytocannabinoids via synthetic routes and reference standards. Core Services: Route Scouting Route synthesis Flow chemistry High Potent Development & Manufacturing Solid State R&D Pre-formulation and Formulation Development Fast Track Programs Upstream & Downstream Processing Development mAbs, ADCs Development

2395 Speakman Drive Mississauga Ontario L5K1B3 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, provides integrated outsourcing solutions for drug substance / API, drug product, biologics and phytocannabinoids as a campus style facility based in North America. Specializing in complex and niche small molecule drug substance and drug product services, including high potent capabilities, we provide support from preclinical to commercial development & manufacturing. In biologics, our expertise lies in the development and scaling of monoclonal antibodies (mAbs) and other mammalian-based therapeutic proteins. Our offerings include upstream & downstream development, analytical services, antibody drug conjugate (ADC) capabilities, and scale-up capacity to 200L for pre-clinical and phase I supply. Additionally, we specialize in producing pharmaceutical-grade, high-quality phytocannabinoids via synthetic routes and reference standards. Core Services: Route Scouting Route synthesis Flow chemistry High Potent Development & Manufacturing Solid State R&D Pre-formulation and Formulation Development Fast Track Programs Upstream & Downstream Processing Development mAbs, ADCs Development

204-3228 South Service Rd Burlington, ON, L7N 3H8 CanadaThe Value & Evidence team (formerly Cornerstone Research Group) at EVERSANA, is a dynamic 100+-person team with small company DNA and large company opportunities. Our work is focused on identifying, demonstrating, and communicating the value of pharmaceutical, biotechnology, and medical device. We offer innovative health economic, health outcomes, market access and data analytic services. We pride ourselves on high-quality work that has been published in a wide range of peer-reviewed journals. Our reputation is for strategic thinking that results in high quality research that meets the needs of our clients, payers, and health technology assessment and regulatory agencies.

Burlington, Ontario, CanadaFermentas International, now part of Thermo Fisher Scientific, provides enzymes, DNA services, electrophoresis products, and reagents.

PO Box 21422 Toronto, Ontario, M5T 0A1 CanadaFlowJEM technology was developed for research and development projects by microfluidic researchers and engineers like you. Our goal is to meet the demands for high quality, fast turnaround time and low cost. Work with us to develop your ideas into prototypes or transition your prototypes to volume production. FlowJEM's innovative manufacturing process allows us to prototype your designs in an economical way. This ensures that your vision is brought to life, unhindered by the limitations of standard designs offered by other companies. In the meanwhile, we provide versatile services and have access to multiple facilities, which can meet different needs.

80 Saint George Street Toronto, ON, M5S 3H4 CanadaFlowJEM technology was developed for research and development projects by microfluidic researchers and engineers like you. Our goal is to meet the demands for high quality, fast turnaround time and low cost. Work with us to develop your ideas into prototypes or transition your prototypes to volume production. FlowJEM's innovative manufacturing process allows us to prototype your designs in an economical way. This ensures that your vision is brought to life, unhindered by the limitations of standard designs offered by other companies. In the meanwhile, we provide versatile services and have access to multiple facilities, which can meet different needs.

181 Lakeshore Road E. Mississauga ON L5G 1G2 CanadaFocal Point Research Inc. (FPR) is a leading North American Scientific Regulatory Affairs and Quality Assurance consulting firm. Established in 1990, we have been trusted consultants to companies worldwide. FPR has the unique ability to assist in many aspects of scientific, regulatory and new product development projects. From early stage development to regulatory approvals, manufacturing and quality assurance, FPR provides comprehensive insight not typically found in a single consulting firm. The broad technical expertise and commitment to excellence at FPR enables us to develop and deliver the services needed, with a “right the first time” approach. FPR deals with small, medium and large corporations, as well as industry associations and government bodies. The elite services that FPR provides are vital to the success of its clients, with strict assurance of confidentiality in all aspects of our work. The multifunctional team at FPR has expertise in areas such as: Cosmetics Natural Health Products OTC’s Drugs Medical Devices Packaging FPR also has extensive knowledge in the development, review, evaluation, and preparation of Regulatory submissions. This knowledge is used to support your needs through a diverse service portfolio, which includes: Health Canada/FDA Submissions Ingredient Reviews Commissioning Clinical Studies Label Reviews Assessing Quality Systems Reviewing Consumer Complaints

2916 South Sheridan Way Oakville, ON, L6J 7J8 CanadaFor over 40 years we've been serving our clients by freeze drying food ingredients and other specialty products. Our customers include many of the world's leading food companies and other specialty processors. With our fully equipped laboratory we are able to help customers develop the products they need. We can also show you how freeze dried ingredients can have a very positive impact on your product's quality. WHY CHOOSE US Real people, real connections Our commitment to excellence in customer service is built into the way we manage our business. We connect with you on a person-to-person level giving you immediate access to expertise and solutions throughout our organization. We believe this approach makes our customer service the best in the industry. We listen to you Consult with us about your unique requirements for products and processes. We will work with you to create a solution including special formulations, custom pre-and post-drying services, and a variety of packaging requirements. Confidentiality is assured.

3080 Yonge Street Suite 6100, Box 66 Toronto, ON, M4N 3N1 CanadaFujiFilm VisualSonics Inc. is a manufacturer of real-time, in vivo, high-resolution micro-imaging systems designed specifically for preclinical research and is a wholly owned subsidiary of SonoSite, Inc. VisualSonics’ imaging technologies allow researchers at pharmaceutical and biotechnology companies, hospitals and universities to conduct research in cardiovascular, cancer, neurobiology and developmental biology areas. The micro-imaging technologies support research applications that include genetic research, phenotypic studies and drug development. VisualSonics high-frequency micro-imaging and photoacoustic platforms combine high-resolution, real-time in vivo imaging with quantifiable data that have been published in over 850 scientific publications globally.

3080 Yonge Street Suite 6100, Box 66 Toronto, Ontario, Canada M4N 3N1FujiFilm VisualSonics Inc. is a manufacturer of real-time, in vivo, high-resolution micro-imaging systems designed specifically for preclinical research and is a wholly owned subsidiary of SonoSite, Inc. VisualSonics’ imaging technologies allow researchers at pharmaceutical and biotechnology companies, hospitals and universities to conduct research in cardiovascular, cancer, neurobiology and developmental biology areas. The micro-imaging technologies support research applications that include genetic research, phenotypic studies and drug development. VisualSonics high-frequency micro-imaging and photoacoustic platforms combine high-resolution, real-time in vivo imaging with quantifiable data that have been published in over 850 scientific publications globally.

45 Ossington Ave 2nd Floor Toronto, Ontario, M6J 2Y9 CanadaFUSE Health is a medical communications agency focused on evolving clinical pathways to deliver better health. We support pharmaceutical and biotech companies’ regulatory, marketing, medical affairs, and training departments with strategy, tactical planning, advisory initiatives, as well as developing brand and therapeutic area assets. Through data, key opinion leader relationships, and multidisciplinary initiatives, we strive to gather the information and insights that become the blueprint for change. Whether we are mapping patient referral patterns or developing toxicity management guidance, the goal of our work extends beyond words on a page, to better patient outcomes.

RR#3, 6570 1st Line West Garafraxa Fergus, ON N1M 2W4Gallus Immunotech offers peptide synthesis, antibody production, antibody purification, and antibody labeling services.

115 Midair Court Brampton, Ontario, L6T 5M3 CanadaGamma-Dynacare Medical Laboratories offers diagnostic assays and clinical trial services.

565 Edward Avenue Richmond Hill, ON, L4C 9W8 CanadaGeneral Ingredient is a supplier of nutritional raw materials to the nutraceutical, food additive, health and sports nutrition industries.

1456 Wallace Road, Unit 1 Oakville Ontario L6L 2Y2 CanadaGL Chemtec International is a contract manufacturing organization, specializing in the custom synthesis of complex molecules.

181 University Ave, Suite 2200, Toronto, Ontario, M5H-3M7, CANADAGreen Earth Nano Science, Inc. (GENS) is an environmental technology company with the company slogan “Green Technologies for Sustainable Future”. Our company is working closely with researchers, scientists and technology companies to enable the commercialization of proprietary breakthrough technologies to reduce energy use, reduce greenhouse gases, air pollution and protect businesses and homes against pollution and bio-contamination.

400 Britannia Road East. Unit 1 Mississauga, Ontario L4Z 1X9 CanadaHach Company manufactures and distributes analytical instruments and reagents used to test the quality of water and other liquids.

1200 Main St. West Hamilton, Ontario, Canada L8N 3Z5Hamilton Health Sciences is a family of seven unique hospitals, a cancer centre and an urgent care centre, serving more than 2.3 million residents of Hamilton and south central Ontario, Canada. Hamilton Health Sciences is the second largest hospital group in Ontario, and serves as a regional referral centre for cardiac, stroke, burns, trauma, neurosurgery, pediatrics, digestive diseases, high-risk obstetrics, cancer, orthopedics and rehabilitation services. With a staff of approximately 11,000, the hospital is the largest employer in the Hamilton region. As an academic teaching hospital with more than 1,100 beds and an affiliation with McMaster University and Mohawk College, Hamilton Health Sciences is committed to providing exemplary health care while advancing excellence in education and health research. The organization’s exceptional track record of inquiry and innovation has earned Hamilton Health Sciences recognition as one of the world’s leading health science research organizations. Staff of Hamilton Health Sciences share a commitment to providing the best possible care to our patients and their families. Guided by our values of respect, caring, innovation and accountability, Hamilton Health Sciences is focused on uniting the best health care has to offer and ensuring our patients have access to the type of care they need when they need it most. The breadth and scope of services offered by HHS, in combination with the hospital's focus on academics and research, make it an employer of choice for many people. Physicians, nurses and clinicians find it attractive to work in HHS' diverse environment where they can be part of a health care team focused on providing the best possible care to patients and their families. Non-medical professionals enjoy bringing their varied talents and skills to a field where priorities are driven by care, not profit.

1200 Main Street West Hamilton, ON, L8N 3Z5 CanadaHamilton Health Sciences is a family of seven unique hospitals, a cancer centre and an urgent care centre, serving more than 2.3 million residents of Hamilton and south central Ontario, Canada. Hamilton Health Sciences is the second largest hospital group in Ontario, and serves as a regional referral centre for cardiac, stroke, burns, trauma, neurosurgery, pediatrics, digestive diseases, high-risk obstetrics, cancer, orthopedics and rehabilitation services. With a staff of approximately 11,000, the hospital is the largest employer in the Hamilton region. As an academic teaching hospital with more than 1,100 beds and an affiliation with McMaster University and Mohawk College, Hamilton Health Sciences is committed to providing exemplary health care while advancing excellence in education and health research. The organization’s exceptional track record of inquiry and innovation has earned Hamilton Health Sciences recognition as one of the world’s leading health science research organizations. Staff of Hamilton Health Sciences share a commitment to providing the best possible care to our patients and their families. Guided by our values of respect, caring, innovation and accountability, Hamilton Health Sciences is focused on uniting the best health care has to offer and ensuring our patients have access to the type of care they need when they need it most. The breadth and scope of services offered by HHS, in combination with the hospital's focus on academics and research, make it an employer of choice for many people. Physicians, nurses and clinicians find it attractive to work in HHS' diverse environment where they can be part of a health care team focused on providing the best possible care to patients and their families. Non-medical professionals enjoy bringing their varied talents and skills to a field where priorities are driven by care, not profit.

30 Springhurst Avenue, Unit 701, Toronto, Ontario M6K 1B3Hangzhou Bm Chemical provides manufacturing and export of special ingredients, APIs, chemical intermediates and nutraceutical ingredients.

National Crystallization Center 700 Ellicott Street Buffalo, NY, 14203 United StatesCrystallization Screening and Cryo-Electron Microscopy The High-Throughput Crystallization Screening Center at HWI (the National Crystallization Center) performs crystal-growth screening experiments for both soluble and membrane biological macromolecules. www.getacrystal.org Experimental screening of 1,536 different chemical cocktails to find initial crystallization conditions for both soluble and membrane biological macromolecules. Each condition is monitored with a robust imaging schedule using brightfield, SONICC, and UV-TPEF imaging methods to quickly identify potential crystallization hits. The Crystallization Center has set up over 25 million crystallization experiments on over 17,000 samples. Our goal is to provide access to expertise, equipment, and technology to facilitate the efficient crystallization of biological macromolecules. Our Cryo-EM facility is purposely designed to produce the highest quality data with our Glacios 200 kV microscope, Volta phase plate, and Falcon 4 and Ceta-D detectors. We offer a range of services up to and including complete structural solutions. https://structuralbiologyservices.com/ About Hauptman-Woodward Medical Research Institute Hauptman-Woodward Medical Research Institute (HWI) is an independent, non-profit research institute with a dedicated team applying their intellect every day to the goal of improving the health of others using structural biology. Founded in 1956, HWI houses researchers dedicated to studying the foundations of disease, looking at biology at the same scale as pharmaceuticals. We have a rich history of innovation, discovery, and education, and are a founder institute of the Buffalo Niagara Medical Campus. www.hwi.buffalo.edu

700 Ellicott Street Buffalo, NY, 14203 United StatesCrystallization Screening and Cryo-Electron Microscopy The High-Throughput Crystallization Screening Center at HWI (the National Crystallization Center) performs crystal-growth screening experiments for both soluble and membrane biological macromolecules. www.getacrystal.org Experimental screening of 1,536 different chemical cocktails to find initial crystallization conditions for both soluble and membrane biological macromolecules. Each condition is monitored with a robust imaging schedule using brightfield, SONICC, and UV-TPEF imaging methods to quickly identify potential crystallization hits. The Crystallization Center has set up over 25 million crystallization experiments on over 17,000 samples. Our goal is to provide access to expertise, equipment, and technology to facilitate the efficient crystallization of biological macromolecules. Our Cryo-EM facility is purposely designed to produce the highest quality data with our Glacios 200 kV microscope, Volta phase plate, and Falcon 4 and Ceta-D detectors. We offer a range of services up to and including complete structural solutions. https://structuralbiologyservices.com/ About Hauptman-Woodward Medical Research Institute Hauptman-Woodward Medical Research Institute (HWI) is an independent, non-profit research institute with a dedicated team applying their intellect every day to the goal of improving the health of others using structural biology. Founded in 1956, HWI houses researchers dedicated to studying the foundations of disease, looking at biology at the same scale as pharmaceuticals. We have a rich history of innovation, discovery, and education, and are a founder institute of the Buffalo Niagara Medical Campus. www.hwi.buffalo.edu

700 ELLICOTT ST BUFFALO, NY, 14203 United StatesAbout Hauptman-Woodward Medical Research Institute Hauptman-Woodward Medical Research Institute (HWI) is an independent, non-profit research institute with a dedicated team applying their intellect every day to the goal of improving the health of others using structural biology. Founded in 1956, HWI houses researchers dedicated to studying the foundations of disease, looking at biology at the same scale as pharmaceuticals. We have a rich history of innovation, discovery, and education, and are a founder institute of the Buffalo Niagara Medical Campus. www.hwi.buffalo.edu

2150 Islington Ave #201 Etobicoke, ON, M9P 3V4 CanadaHealthDiary is a technology partner in clinical research and health studies, offering patient diary solutions also known as electronic Patient Reported Outcomes (ePRO), Electronic Data Capture (EDC) and patient registries. HealthDiary is cloud based and designed to collect data, manage, and monitor multi-centre, multi-language studies.

2150 Islington Avenue, Suite 201 Toronto, Ontario M9P 3V4 CanadaHealthDiary is a technology partner in clinical research and health studies, offering patient diary solutions also known as electronic Patient Reported Outcomes (ePRO), Electronic Data Capture (EDC) and patient registries. HealthDiary is cloud based and designed to collect data, manage, and monitor multi-centre, multi-language studies.

Toronto, ON CanadaHealthGene Corp offers DNA extraction services, particularly for animals.

2175 Keele St. Toronto, ON M6M 3Z4 CanadaHealthGene Corp offers DNA extraction services, particularly for animals.

Toronto, ON, CanadaHealthGene Corp offers DNA extraction services, particularly for animals.

Hamilton, ON CanadaHemostasis Reference Laboratory offers coagulation analysis, DNA analysis, cytokine screening, and blood screening tests.

1100 Bennett Road Bowmanville, Ontario, Canada L1C 3K5Holburn provides research consulting, clinical trial services, and management services.

Bowmanville, ON CanadaHolburn provides research consulting, clinical trial services, and management services.

555 University Avenue Toronto, Ontario, M5G 1X8 CanadaThe Hospital for Sick Children (SickKids), affiliated with the University of Toronto, is Canada's most research-intensive hospital and the largest centre dedicated to improving children's health in the country. As innovators in child health, SickKids improves the health of children by integrating care, research and teaching. With a staff that includes professionals from all disciplines of health care and research, SickKids provides the best in complex and specialized care by creating scientific and clinical advancements, sharing knowledge and expertise and championing the development of an accessible, comprehensive and sustainable child health system.

Mississaga, Ontario, CanadaIBI Biosolutions offers ligand docking, in silico drug design, molecular modeling, epitope development, sequence analysis, biostatistics and cheminformatic services.

288 Wildcat Road, Toronto, ON, M3J 2N5 CanadaIBL International offers reagents, antibodies, and assay kit products for purchase.

60 Pineview Drive Buffalo NY 14228IMMCO Diagnostics provides histology, serology, genetics, assay development, and pathology.

Burlington, Ontario, CanadaIMMCO Diagnostics provides histology, serology, genetics, assay development, and pathology.

1 Seneca Street 24th Floor Buffalo, NY, 14203 United StatesWe enable access to global clinical research studies. Launch your clinical study and find thousands of vetted, eligible participants, sites and primary investigators in minutes. Clinical Research services include: Investigational site finder, Principal Investigator finder, Site Feasibility, ICF writing & translations, Ethics submissions, Regulatory submissions, site selection & initiation, Site training, Patient recruitment, Clinical Trial Monitoring & reporting, Central lab services, IP Accountability, Safety Reporting & Data Management

Toronto, ON CanadaInnovaTox provides pharmaceutical development and environmental health assessments.

53 Romano Crescent Woodbridge, ON L4N 7N2 CanadaInnovaTox provides pharmaceutical development and environmental health assessments.

McMaster University Health Science Centre 4H31 1280 Main Street West Hamilton, Ontario L8S 4K1

Toronto, ON CanadaIntellipharmaceutics provides life cycle management and the enhancement of new chemical entities (NCEs).

30 Worcester Road Toronto, Ontario Canada M9W 5X2Intellipharmaceutics provides life cycle management and the enhancement of new chemical entities (NCEs).

101 College Street Toronto, ON, M5G 1L7 CanadaIn July 2005, Interface Biologics moved into Toronto’s acclaimed MaRS Innovation Centre---a collaborative facility dedicated to accelerating emerging technologies, located near the University of Toronto campus and seven specialty hospitals.

720 King Street West, 7th Floor (NORTH ELEVATORS) Toronto, ON M5V 2T3 CanadaKendle Early Stage provides early stage development expertise to pharmaceutical and biotechnology companies.

101 MacIntosh Boulevard Concord, Ontario Canada L4K 4R5KIK Custom Products is a full service manufacturer of aerosols, liquids and solids

170 Shields Ct., Unit 2 Markham, Ontario Canada L3R9T5

Toronto, ON CanadaLallemand provides yeast and bacteria development and production services.

20 Martin Ross Ave Toronto, Ontario, M3J 2K8 CanadaLGC is a global manufacturer and distributor of high-quality certified reference materials, research chemicals (TRC), genomics solutions, proficiency testing, and analytical testing services. We employ our 180 years of scientific heritage, cutting-edge expertise in measurement science and track record of innovation to progress research & development and improve outcomes across pharmaceuticals, diagnostics, food, environment, industry and consumer products. Our products and services stand out, producing to the highest quality, continually adapting to changing regulation, and providing expert support and documentation to help ensure the accuracy of your analytical results. LGC. Science for a safer world. We serve as the UK’s National Measurement Institute for chemical and bioanalytical measurements. Meet our brands: - TRC TRC offers 150,000+ research chemicals, with a large inventory readily available globally. Discover our wide range of bioactive small molecules, stable isotope labelled & controlled substances to advance your research. - AXIO Proficiency Testing AXIO Proficiency Testing is a global provider of proficiency testing schemes. We support over 13,000 laboratories, with over 2,700 proficiency tests, in over 165 countries worldwide, to meet their regulatory and accreditation requirements. - Dr Ehrenstorfer Dr Ehrenstorfer provides a comprehensive range of high-quality reference materials. Over 50% of the portfolio is accredited to ISO 17034, with 14,000+ reference materials available. - LGC Industrial LGC Industrial offers innovative & agile measurement tools for a safe global infrastructure. Combining VHG, ARMI, MBH & Paragon Scientific, we deliver a wide range of petrochemical, metal, mining, powder & physical reference materials. - Mikromol Mikromol offers a portfolio of 7,000+ high-quality accredited pharmaceutical API, impurity & excipient reference standards, >95% ready to ship alongside market leading COAs. We also provide RMs management services & custom manufacturing. - Clinical Diagnostics LGC Clinical Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions, biological and reagent component materials for the extended life sciences industry. - LGC Genomics LGC Genomics offers a custom DNA sequencing service. It is comprised of Biosearch Technologies & LGC Axolabs. i) Biosearch Technologies offers GMP and RUO Oligonucleotides, Molecular biology reagents, NGS kits and enzymes, Oligo synthesis reagents and instruments, PCR reagents and instruments, and sample prep reagents and instruments. ii) LGC Axolabs offers a unique services portfolio for the development of nucleic acid therapeutics and nucleic acid-based medicines.

Milani Blvd Vaughan, Ontario, L4H4M4 CanadaLGC is a global manufacturer and distributor of high-quality certified reference materials, research chemicals (TRC), genomics solutions, proficiency testing, and analytical testing services. We employ our 180 years of scientific heritage, cutting-edge expertise in measurement science and track record of innovation to progress research & development and improve outcomes across pharmaceuticals, diagnostics, food, environment, industry and consumer products. Our products and services stand out, producing to the highest quality, continually adapting to changing regulation, and providing expert support and documentation to help ensure the accuracy of your analytical results. LGC. Science for a safer world. We serve as the UK’s National Measurement Institute for chemical and bioanalytical measurements. Meet our brands: - TRC TRC offers 150,000+ research chemicals, with a large inventory readily available globally. Discover our wide range of bioactive small molecules, stable isotope labelled & controlled substances to advance your research. - AXIO Proficiency Testing AXIO Proficiency Testing is a global provider of proficiency testing schemes. We support over 13,000 laboratories, with over 2,700 proficiency tests, in over 165 countries worldwide, to meet their regulatory and accreditation requirements. - Dr Ehrenstorfer Dr Ehrenstorfer provides a comprehensive range of high-quality reference materials. Over 50% of the portfolio is accredited to ISO 17034, with 14,000+ reference materials available. - LGC Industrial LGC Industrial offers innovative & agile measurement tools for a safe global infrastructure. Combining VHG, ARMI, MBH & Paragon Scientific, we deliver a wide range of petrochemical, metal, mining, powder & physical reference materials. - Mikromol Mikromol offers a portfolio of 7,000+ high-quality accredited pharmaceutical API, impurity & excipient reference standards, >95% ready to ship alongside market leading COAs. We also provide RMs management services & custom manufacturing. - Clinical Diagnostics LGC Clinical Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions, biological and reagent component materials for the extended life sciences industry. - LGC Genomics LGC Genomics offers a custom DNA sequencing service. It is comprised of Biosearch Technologies & LGC Axolabs. i) Biosearch Technologies offers GMP and RUO Oligonucleotides, Molecular biology reagents, NGS kits and enzymes, Oligo synthesis reagents and instruments, PCR reagents and instruments, and sample prep reagents and instruments. ii) LGC Axolabs offers a unique services portfolio for the development of nucleic acid therapeutics and nucleic acid-based medicines.

101 Milani Blvd Vaughan, Ontario, L4H4M4 CanadaLGC is a global manufacturer and distributor of high-quality certified reference materials, research chemicals (TRC), genomics solutions, proficiency testing, and analytical testing services. We employ our 180 years of scientific heritage, cutting-edge expertise in measurement science and track record of innovation to progress research & development and improve outcomes across pharmaceuticals, diagnostics, food, environment, industry and consumer products. Our products and services stand out, producing to the highest quality, continually adapting to changing regulation, and providing expert support and documentation to help ensure the accuracy of your analytical results. LGC. Science for a safer world. We serve as the UK’s National Measurement Institute for chemical and bioanalytical measurements. Meet our brands: - TRC TRC offers 150,000+ research chemicals, with a large inventory readily available globally. Discover our wide range of bioactive small molecules, stable isotope labelled & controlled substances to advance your research. - AXIO Proficiency Testing AXIO Proficiency Testing is a global provider of proficiency testing schemes. We support over 13,000 laboratories, with over 2,700 proficiency tests, in over 165 countries worldwide, to meet their regulatory and accreditation requirements. - Dr Ehrenstorfer Dr Ehrenstorfer provides a comprehensive range of high-quality reference materials. Over 50% of the portfolio is accredited to ISO 17034, with 14,000+ reference materials available. - LGC Industrial LGC Industrial offers innovative & agile measurement tools for a safe global infrastructure. Combining VHG, ARMI, MBH & Paragon Scientific, we deliver a wide range of petrochemical, metal, mining, powder & physical reference materials. - Mikromol Mikromol offers a portfolio of 7,000+ high-quality accredited pharmaceutical API, impurity & excipient reference standards, >95% ready to ship alongside market leading COAs. We also provide RMs management services & custom manufacturing. - Clinical Diagnostics LGC Clinical Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions, biological and reagent component materials for the extended life sciences industry. - LGC Genomics LGC Genomics offers a custom DNA sequencing service. It is comprised of Biosearch Technologies & LGC Axolabs. i) Biosearch Technologies offers GMP and RUO Oligonucleotides, Molecular biology reagents, NGS kits and enzymes, Oligo synthesis reagents and instruments, PCR reagents and instruments, and sample prep reagents and instruments. ii) LGC Axolabs offers a unique services portfolio for the development of nucleic acid therapeutics and nucleic acid-based medicines.

1A Dixie Avenue, Niagara-on-the-Lake ON L0S 1J0 CanadaLife Chemicals is a major producer and supplier of HTS compounds and a well-recognized provider of custom synthesis and computational chemistry services to pharmaceutical, biotech, crop science companies, and academic institutions across the globe. Developing its business development Life Chemicals has associated and headquartered a family of R&D chemical companies, namely I.F. Lab, Spoluka, Life Chemicals Inc., Life Chemicals USA (Woodbridge, CT), and Life Chemicals Europe (Munich, Germany), to operate as an integral whole where every single company is focused on its individual range of products and services and, at the same time, all are motivated by achieving their common goal. Today Life Chemicals is a fully integrated platform for early drug discovery, providing complete range of contract research and contract manufacturing services. Our broad experience in synthetic organic chemistry and up-to-date equipment ensure high quality services in custom synthesis of drug-like compounds and advanced Building Blocks in mg to multiKG quantities, design and synthesis of combinatorial libraries, route scouting and production scale-up. Our expertise in computational chemistry and employment of versatile in silico techniques, such as similarity and pharmacophore search, molecular descriptors analysis, docking screening and protein modeling, enable careful design of Fragment collections, Targeted and Focused libraries and customized sets of compounds. Our keen understanding of drug discovery process with computer-assisted approaches, our knowledge of medicinal chemistry and our solid scientific background supported with a powerful production infrastructure allow us to provide efficient solutions for R&D programs of our customers, including hit-to-lead and lead optimization, improvement of drug potency, selectivity and ADMET, development of QSAR models and medchem design.

1 University Avenue 3rd floor Toronto, Ontario, M5J2P1 CanadaLighthouse Outcomes assists our customers by generating and synthesizing evidence to make informed decisions. We provide technical and communication solutions to clients in the pharmaceutical, health technology and public health spaces. Our work is focused on four areas: evidence generation, knowledge synthesis, decision analysis and health economics. Our mission is to solve complex problems in the health sciences to improve people’s lives. We develop focused and custom solutions to our customers’ health sciences problems applying appropriate tools to achieve timely results. We believe that every client’s problem is unique and requires a custom solution applying the right tools for the job to develop a solution that is as simple as possible, but not simpler. We are a diverse team of epidemiologists, statisticians, health economists and content specialists working together to quickly service our clients’ most complex health sciences problems. Collectively, we have worked on hundreds of projects in diverse disease areas, globally. Our core strengths are in the application of quantitative approaches to the development of state-of-the-art evidence syntheses, network meta-analysis, complex decision modeling and health economics analyses. We are ready to bring our collective experience to bear on your most pressing problems.

150 Research Lane, Unit 100 University of Guelph Research Park Centre Guelph, ON N1G 4T2 CanadaLipid Analytical Laboratories (LAL) offers analysis on various lipids and fatty acid components in biological materials.

2978 Main Street Buffalo, NY 14214

700 University Avenue North Toronto, Ontario, M5G 1Z5 CanadaMBC — a directnetwork company — is the official Scientist.com outlet of directnetwork GmbH, a Swiss precision‑medicine CRO focused on simplifying and accelerating access to high‑quality human biospecimens, cell lines, and real‑world data. Our work bridges the gap between biobanks, clinical sites, and biotech innovators, enabling faster and more cost‑effective translational research and preclinical development. We provide ethically sourced, well‑characterized human biospecimens—including fresh material—as well as real‑world data representing diverse ethnic backgrounds and homogeneity criteria. Our network of clinical centers and biobanks spans EU and non‑EU Europe, Asia, North America, and Australia, ensuring broad geographic coverage and access to diverse patient populations. Our portfolio includes disease‑specific samples (e.g., blood, PBMCs, and other matrices) paired with matched healthy controls to support robust study design. Our mission is to empower partners to accelerate drug discovery, validation, and development while reducing operational complexity, timelines, and cost. In addition to biospecimen procurement, we collaborate with a specialized downstream analytics partner offering advanced multi‑omics, bioinformatics, and data‑integration capabilities. This enables clients to move seamlessly from sample acquisition to high‑value scientific insights.

1151 Gorham Street, Unit #8 Newmarket, Ontario Canada L3Y 8Y1McCarthy Consulting Services provides consulting for drugs, biologics, medical devices, foods and cosmetics.

789 Don Mills Road, Suite 802 Toronto, Ontario , M3C 1T5 CanadaWith over 35 years of quality service, McDougall Scientific is one of the most experienced Clinical Research Organizations around. McDougall's core services in statistics and data management, both paper-based and Electronic Data Capture (EDC), have established well-defined business processes within the company. All processes are supported by a robust Quality Master Plan, Standard Operating Procedures (SOPs), and a validated computing infrastructure. McDougall's strict adherence to its best practices over 25+ years has transferred to an expanding suite of services that now includes hosted document management services.

789 Don Mills Road, Suite 802, Toronto, Ontario M3C 1T5 CanadaWith over 35 years of quality service, McDougall Scientific is one of the most experienced Clinical Research Organizations around. McDougall's core services in statistics and data management, both paper-based and Electronic Data Capture (EDC), have established well-defined business processes within the company. All processes are supported by a robust Quality Master Plan, Standard Operating Procedures (SOPs), and a validated computing infrastructure. McDougall's strict adherence to its best practices over 25+ years has transferred to an expanding suite of services that now includes hosted document management services.

661 University Ave, Suite 1300 Toronto, Ontario, M5G 0B7 CanadaMediphage Bioceuticals is a spin-off from the University of Waterloo. Mediphage is a non-viral gene therapy company located at JLabs in Toronto, Canada. Our proprietary core technology, ministring DNA (msDNA), is a novel non-viral vector that is designed to overcome critical challenges facing viral gene therapies and leverage advancements of non-viral gene therapy technologies. Leveraging the versatility of our msDNA non-viral technology, we are developing innovative solutions to the challenges faced with genetic and infectious diseases that have limited, or no, treatment options available at present.

6303 Airport Road, Suite 500 Mississauga, ON L4V 1R8 CANADAMerge Healthcare specializes in clinical systems and offers cloud-based solutions for imaging and data analytics.

265 Watline AvenueMicrobix Biosystems provides antigens, adenovirus solutions, and contract manufacturing.

Mississauga, ON CanadaMicrobix Biosystems provides antigens, adenovirus solutions, and contract manufacturing.

109 Railside Road, Suite 305, Toronto, Ontario M3A 1B2, CANADAMightex Systems, with operations based in Toronto, Canada, and in the Silicon Valley, California, is a leading supplier of photonic products and services for a broad spectrum of applications including industrial imaging, bio-photonic solutions, LED illumination, machine vision, life & health sciences, and industrial test & measurement etc. OEM Services: With a world-class OEM design team, Mightex offers a broad range of customized solutions in order to meet individual customer’s unique requirements. At Mightex, our mission is to provide you - our customers - with high quality solution at low cost and in a timely fashion. Our engineering team will partner with you to create “total solutions” to fit your requirements.

1241 Railside Road, Suite 305 Toronto, Ontario, M3A 1B2 CanadaMightex Systems, with operations based in Toronto, Canada, and in the Silicon Valley, California, is a leading supplier of photonic products and services for a broad spectrum of applications including industrial imaging, bio-photonic solutions, LED illumination, machine vision, life & health sciences, and industrial test & measurement etc. OEM Services: With a world-class OEM design team, Mightex offers a broad range of customized solutions in order to meet individual customer’s unique requirements. At Mightex, our mission is to provide you - our customers - with high quality solution at low cost and in a timely fashion. Our engineering team will partner with you to create “total solutions” to fit your requirements.

1540 Maple Road Williamsville, NY, 14221 United StatesMillard Fillmore Suburban Hospital is a full service, 265-bed acute care teaching hospital and a part of Kaleida Health, Western New York’s largest healthcare provider Located in Amherst, one of Western New York’s fastest growing, and safest suburbs, the facility is proud to serve those residing in the local community and nearby areas. The services offered at Millard Fillmore Suburban Hospital include: Acute care nursing units Ambulatory surgery Cardiology Cardiac non-invasive procedures Emergency Department GI Lab Imaging with 3D Tomosynthesis Mammography Interventional Radiology Laboratory Obstetrics and Gynecology Palliative Care Pulmonary Function Lab Respiratory Therapy Urology Suite; Vascular Lab Women’s Services Surgical services in the specialty areas of: Hand Surgery Minimally Invasive Robotic Surgery Neurosurgery Orthopedics

1540 Maple Road Williamsville, NY , 14221 United StatesMillard Fillmore Suburban Hospital is a full service, 265-bed acute care teaching hospital and a part of Kaleida Health, Western New York’s largest healthcare provider Located in Amherst, one of Western New York’s fastest growing, and safest suburbs, the facility is proud to serve those residing in the local community and nearby areas. The services offered at Millard Fillmore Suburban Hospital include: Acute care nursing units Ambulatory surgery Cardiology Cardiac non-invasive procedures Emergency Department GI Lab Imaging with 3D Tomosynthesis Mammography Interventional Radiology Laboratory Obstetrics and Gynecology Palliative Care Pulmonary Function Lab Respiratory Therapy Urology Suite; Vascular Lab Women’s Services Surgical services in the specialty areas of: Hand Surgery Minimally Invasive Robotic Surgery Neurosurgery Orthopedics

100 College Street, University of Toronto Toronto, ON M5G 1L5, CAMitacs is a national, not-for-profit organization that has designed and delivered research and training programs in Canada for 15 years. Working with 60 universities, thousands of companies, and both federal and provincial governments, we build partnerships that support industrial and social innovation in Canada. Mitacs was founded in 1999 as a Canadian Network of Centres of Excellence, dedicated to supporting applied and industrial research in mathematical sciences and associated disciplines. In 2003, we launched a research internship program designed to increase deployment of highly educated graduates into the private sector. Open to all disciplines since 2007, Mitacs has expanded in response to industrial and university needs, including programs in R&D management, professional skills development, and international research training. Fully independent since 2011, Mitacs remains committed to its core vision of supporting research-based innovation and continues to work closely with its partners in industry, academia, and government. From aerospace systems to childhood literacy rates, Mitacs-funded research helps to strengthen connections, improve economic performance, and create jobs. Over the past 15 years, we have supported more than 10,000 research internships, trained more than 19,000 student and postdoc career-skills participants, and supported more than 1,300 international research collaborations.

70 EastBeaver Creek Road #39, Richmond Hill, Toronto Ontario, Canada L4B 3B2Molcan Corporation is involved in design, research, development and production of fine chemicals, API related compounds, impurities, intermediates, metabolites, internal standards etc. using chemical synthesis and bio-fermentation processes. Our strengths in microbial fermentation, organic synthesis and natural products chemistry allow us to bring thousands of niche molecules from laboratory to the market place in relatively short period of time. Our R&D and production facilities are well equipped with modern instrumentation and over 100,000 L of reactor capacity which are supported with experienced scientific, engineering and quality assurance teams. Our clients include research-based multinational pharmaceutical companies, biotech companies, generic pharmaceutical manufacturers, natural health products and nutraceutical manufacturers, government and independent testing laboratories, universities and research institutions, cosmetic formulators, contract research organizations and contract manufacturers, etc. Our products are supplied for R&D or industrial use, not intended for human or animal use, unless otherwise mentioned.

Suite #5700 First Canadian Place, 100 King Street West Toronto, Ontario, M5X1C7 CanadaMBP is a family-owned lab supply business that can help with consumables, reagents, custom oligos, and equipments. We also offer a revolutionary temperature/facility monitoring solution to help pharmaceutical companies maintain FDA and CDA 21 compliance.

101 Holiday Inn Drive / #21905 Hespeler Cambridge, ON N3C 0E6

100 Allstate Parkway Markham, ON, L3R 6H3 CanadaOPKO Health, Inc. is a multi-national pharmaceutical and diagnostics company that aims to establish industry-leading positions in large and rapidly growing medical markets by leveraging our discovery, development, and commercialization expertise and our novel and proprietary technologies.

Toronto, ON CanadaNeuroImage offers brain imaging, molecular imaging, biomarker development, animal models of disease, and image analysis services.

2181 Yonge Street, Suite 801 Toronto, Ontario M4S 3H7 CanadaNeuroImage offers brain imaging, molecular imaging, biomarker development, animal models of disease, and image analysis services.

661 University Avenue, Suite 1300 Canada Toronto, ON, M5G 1M1 Canada

661 University Avenue Suite 1300 Toronto, ON, M5G 1M1 Canada

875 Ellicott Street, Buffalo, NY 14203 USAThe New York Center for Nanomedicine Research (NYCNMR) combines the expertise of leading research in the fields of nanotechnology, medicine, biology, chemistry and advanced imaging to the discovery of nanoscale therapeutic, diagnostic, and drug delivery agents. NYCNMR is in the forefront of breaking biological barriers in regards to drug delivery (BBB & BNB) and targeting systems. Fostering synergies between different disciplines, the center is addressing new methods for innovation.

3300 - 20 Queen Street West Toronto Ontario M5H 3R3Nexus Oncology offers data management, site selection, project management, and drug development consultancy to support studies in oncology.

5795 Lewiston Rd, Niagara Univ, NY 14109NU educates its students and enriches their lives through programs and career preparation, informed by the Catholic and Vincentian traditions. Enabling Goals As a university, Niagara prepares its students for positions of responsibility in the professions and in the broader society. Through teaching, research and service in programs of study at the baccalaureate and graduate levels, Niagara seeks to develop within its students a passion for learning. The university's commitment to the Catholic faith provides perspective in the search for truth and meaning. Catholic doctrine and its moral code inspire respect for the God-given dignity of every person and all faith traditions. Students experience the vision and reality of a gospel-based, value-centered education. As a Vincentian university, Niagara draws inspiration from St. Vincent de Paul, who organized his contemporaries to respond compassionately to people's basic needs. Continuing this tradition, Niagara seeks to inspire its students to serve all members of society, especially the poor and oppressed, in local communities and in the larger world. Overall, through its curricular and extracurricular programs, Niagara University seeks to develop the whole person, mind, body, heart and soul, for the benefit of one's personal and professional life.

5795 Lewiston Rd, Niagara Univ, , NY, 14109 United StatesNU educates its students and enriches their lives through programs and career preparation, informed by the Catholic and Vincentian traditions. Enabling Goals As a university, Niagara prepares its students for positions of responsibility in the professions and in the broader society. Through teaching, research and service in programs of study at the baccalaureate and graduate levels, Niagara seeks to develop within its students a passion for learning. The university's commitment to the Catholic faith provides perspective in the search for truth and meaning. Catholic doctrine and its moral code inspire respect for the God-given dignity of every person and all faith traditions. Students experience the vision and reality of a gospel-based, value-centered education. As a Vincentian university, Niagara draws inspiration from St. Vincent de Paul, who organized his contemporaries to respond compassionately to people's basic needs. Continuing this tradition, Niagara seeks to inspire its students to serve all members of society, especially the poor and oppressed, in local communities and in the larger world. Overall, through its curricular and extracurricular programs, Niagara University seeks to develop the whole person, mind, body, heart and soul, for the benefit of one's personal and professional life.

5795 Lewiston Rd, Niagara Univ, , NY , 14109 United StatesNU educates its students and enriches their lives through programs and career preparation, informed by the Catholic and Vincentian traditions. Enabling Goals As a university, Niagara prepares its students for positions of responsibility in the professions and in the broader society. Through teaching, research and service in programs of study at the baccalaureate and graduate levels, Niagara seeks to develop within its students a passion for learning. The university's commitment to the Catholic faith provides perspective in the search for truth and meaning. Catholic doctrine and its moral code inspire respect for the God-given dignity of every person and all faith traditions. Students experience the vision and reality of a gospel-based, value-centered education. As a Vincentian university, Niagara draws inspiration from St. Vincent de Paul, who organized his contemporaries to respond compassionately to people's basic needs. Continuing this tradition, Niagara seeks to inspire its students to serve all members of society, especially the poor and oppressed, in local communities and in the larger world. Overall, through its curricular and extracurricular programs, Niagara University seeks to develop the whole person, mind, body, heart and soul, for the benefit of one's personal and professional life.

15 Bruyers Mews Suite 1508 Toronto, Ontario, M5V 0A7 CanadaNode Medcom is a boutique global medical communications partner driving scientific impact for pharma and biotech through strategic medical education, HCP engagement, advisory boards, publications, and tailored multichannel medical communication strategies.

Thorold, ON CanadaNorgen Biotek provides researchers with innovative kits for Molecular Diagnostics (MDx), Sample Collection/Preservation [from Urine, Stool, Plasma/Serum/Blood, Saliva] and microRNA/RNA/DNA/Protein Purification/Clean-Up (spin-column/96-well). Our kits feature exceptional quality, ease-of-use and sensitivity. Norgen Biotek provides researchers with the tools to address any sample preservation and preparation challenge.

3430 Schmon Parkway Thorold, Ontario L2V 4Y6 CanadaNorgen Biotek provides researchers with innovative kits for Molecular Diagnostics (MDx), Sample Collection/Preservation [from Urine, Stool, Plasma/Serum/Blood, Saliva] and microRNA/RNA/DNA/Protein Purification/Clean-Up (spin-column/96-well). Our kits feature exceptional quality, ease-of-use and sensitivity. Norgen Biotek provides researchers with the tools to address any sample preservation and preparation challenge.

70 Little Creek Road Mississauga, ON, L5R 3E3 CanadaNormin Health was founded by Dr. Wendong Chen in 2012. Since then, Normin Health started the first observational study using hospital data to assess treatment outcomes and hospital costs associated with first-line and second-line chemotherapies in patients with non-squamous non-small cell lung cancer. With the huge success of this very first project, Normin Health has built up a highly specialized team to conduct real-world studies and develop health economic models to meet the evidence needs of developing market access strategies, supporting reimbursement submissions, and supporting commercial promotions. Normin Health has provided services to many international pharmaceutical and medical devices companies. These companies include Eli Lilly, Xian Janssen, BMS, Novartis Oncology, Gilead, Celgene, J &J, and BD. Normin Health has been highly recognized by these clients for professionalism, innovation, and quality. Normin Health is also actively developing new business to better meet market access needs. These new businesses include the development of mobile phone APP communication tool for better communications of the clinical and economic values of medical products and the development of patient follow-up mobile phone APP to fill the current real-world data gaps.

2000 Ellesmere Road Unit 16 Scarborough, Ontario, M1H2W4 Canada

Guelph, ON CanadaNutrasource Diagnostics Inc. (NDI) is a contract research organization and regulatory consulting firm specializing in regulatory consulting, clinical trials and product analytics.

120 Research Lane, Suite 203 University of Guelph Research Park Guelph, ON N1G 0B4 CanadaNutrasource Diagnostics Inc. (NDI) is a contract research organization and regulatory consulting firm specializing in regulatory consulting, clinical trials and product analytics.

Toronto, ON CanadaOntario Cancer Biomarker Network (OCBN) focuses on discovery and development on novel biomarkers for human diseases in addition to offering mass spectrometry, immunoassays, and other assay services to support proteomics, genomics, clinical oncology, and drug development.

Ontario Institute for Cancer Research MaRS Centre 661 University Avenue, Suite 510 Toronto, Ontario, Canada M5G 0A3The Ontario Tumour Bank (OTB) provides a viable solution for cancer researchers who often face challenges in obtaining the quality and number of biospecimens required for their studies. In doing so, OTB accelerates cancer research for the development of better patient diagnostics and therapies. Vision Scientific and technological advances in genomics, proteomics, and bioinformatics are providing new insight into the cause and treatment of cancer. The analysis of human tumours offers academic and industry researchers a window into the molecular and genetic world of cancer. Through the analysis of tumours, researchers have learned about the molecular makeup of tumours, discovered biomarkers that are characteristic of tumours and identified genes responsible for specific cancers. This knowledge creates exciting possibilities for the creation of new diagnostic and prognostic tools and for the identification of targets for new drug therapies. In order for the potential of the genomics revolution to be realized, research scientists and clinicians must analyze the molecular makeup of large numbers of human tumour tissues. Although researchers can use models of the disease such as cell lines and animal tumours, at some point it becomes essential to study human tissues to understand how a disease like cancer develops in humans. Thus, researchers require access to collections of well-preserved and well-characterized tumour tissue accompanied by high-quality clinical data. Biospecimens are the key to the development and testing of next-generation diagnostics and treatments. OTB makes this type of research possible by providing the materials needed to drive high-impact studies.

270 Longwood Ave., Room A216 Hamilton, ON, L8P 0A1 CanadaOrganoBiotech is a biotech startup founded in 2021 out of Dr. Boyang Zhang’s lab at McMaster University (Canada). We aim to improve drug development by integrating high-throughput Organ-on-a-Chip systems with machine learning–based analysis. Our offerings include scalable and automated 3D tissue culture platforms, supporting instrumentation, and contract research services that help partners design, execute, and interpret advanced preclinical models.

291 Bethpage Drive Oakville, ON, L6M 1R5 CanadaOrganoBiotech is a biotech startup founded in 2021 out of Dr. Boyang Zhang’s lab at McMaster University (Canada). We aim to improve drug development by integrating high-throughput Organ-on-a-Chip systems with machine learning–based analysis. Our offerings include scalable and automated 3D tissue culture platforms, supporting instrumentation, and contract research services that help partners design, execute, and interpret advanced preclinical models.

OTAVA Ltd. 400 Applewood Crescent, Unit 100 Vaughan, Ontario, L4K 0C3 CANADAOTAVA offers: Synthesis of high-quality small organic compounds for HTS, chemical building blocks and intermedieates Full range of custom synthesis and hit-to-lead optimization services Rational design of inhibitors of protein kinases and other drug targets Wide selection of target-focused libraries, design on request option Molecular modeling/computational chemistry services Development of novel fluorescent probes

400 Applewood Crescent, Unit 100 Concord, ON, L4K 0C3 CanadaOTAVA offers: Synthesis of high-quality small organic compounds for HTS, chemical building blocks and intermedieates Full range of custom synthesis and hit-to-lead optimization services Rational design of inhibitors of protein kinases and other drug targets Wide selection of target-focused libraries, design on request option Molecular modeling/computational chemistry services Development of novel fluorescent probes

155 College Street, Suite 424 Toronto, ON M5T, CAPOPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE The Institute for Clinical Evaluative Sciences (ICES) leads cutting-edge studies that evaluate health care delivery and outcomes. ICES researchers access a vast and secure array of Ontario’s health-related data, including population-based health surveys, anonymous patient records, as well as clinical and administrative databases. ICES goes to great lengths to protect privacy and is recognized as an international leader in maintaining the privacy and security of health information. WORLD-CLASS RESEARCH TEAMS ICES is a community of research, data and clinical experts. Many ICES scientists are internationally recognized and a number of them are practicing clinicians who understand the everyday challenges of health care delivery. They lead multidisciplinary teams that include expert statisticians and epidemiologists, as well as specialists in knowledge translation and information security, privacy and information technology. The diversity within these teams and their expertise at using ICES’ outstanding array of linked datasets is the foundation of the innovative approach to research at ICES. IMPACT ICES research results in an evidence base that is published as atlases, investigative reports and peer-reviewed papers, and is used to guide decision-making and inform changes in health care policy and delivery. Many ICES reports are undertaken to answer specific questions (known as Applied Health Research Questions) posed by health system stakeholders and policy-makers. ICES research and reports influence the design, implementation and evaluation of health policy and the delivery of health care. ICES studies and reports are highly regarded in Canada and abroad. INDEPENDENCE ICES is an independent not-for-profit corporation, and takes pride in its international reputation as a trusted, impartial and credible source of high quality health and health services research and evidence. ICES receives core funding from the Ontario Ministry of Health and Long-Term Care. ICES faculty and staff have highly successful track records competing for peer-reviewed grants from federal agencies, such as the Canadian Institutes of Health Research, and from provincial as well as international funding bodies.

G1 06, 2075 Bayview Avenue Toronto, Ontario , M4N 3M5 CanadaPOPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE The Institute for Clinical Evaluative Sciences (ICES) leads cutting-edge studies that evaluate health care delivery and outcomes. ICES researchers access a vast and secure array of Ontario’s health-related data, including population-based health surveys, anonymous patient records, as well as clinical and administrative databases. ICES goes to great lengths to protect privacy and is recognized as an international leader in maintaining the privacy and security of health information. WORLD-CLASS RESEARCH TEAMS ICES is a community of research, data and clinical experts. Many ICES scientists are internationally recognized and a number of them are practicing clinicians who understand the everyday challenges of health care delivery. They lead multidisciplinary teams that include expert statisticians and epidemiologists, as well as specialists in knowledge translation and information security, privacy and information technology. The diversity within these teams and their expertise at using ICES’ outstanding array of linked datasets is the foundation of the innovative approach to research at ICES. IMPACT ICES research results in an evidence base that is published as atlases, investigative reports and peer-reviewed papers, and is used to guide decision-making and inform changes in health care policy and delivery. Many ICES reports are undertaken to answer specific questions (known as Applied Health Research Questions) posed by health system stakeholders and policy-makers. ICES research and reports influence the design, implementation and evaluation of health policy and the delivery of health care. ICES studies and reports are highly regarded in Canada and abroad. INDEPENDENCE ICES is an independent not-for-profit corporation, and takes pride in its international reputation as a trusted, impartial and credible source of high quality health and health services research and evidence. ICES receives core funding from the Ontario Ministry of Health and Long-Term Care. ICES faculty and staff have highly successful track records competing for peer-reviewed grants from federal agencies, such as the Canadian Institutes of Health Research, and from provincial as well as international funding bodies.

2100 Syntex Court Mississauga, Ontario L5N 7K9 CanadaPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

111 Consumers Drive Whitby, Ontario L1N 5Z5 CanadaPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

Toronto, ON CanadaPathMatrix developed a software platform for modeling of normal physiology and disease pathophysiology in support of virtual screening, disease model simulation, in silico predictions, and signal transduction pathway studies.

Mississauga, ON CanadaPharmachem Access offers CMC consulting, process analytical technology, regulatory affair, technology transfer, and process design.

4405-2230 Lakeshore Blvd W Toronto, Ontario, M8V0B2 CanadaAn advisory CRO that provides consulting services to biotechnology and pharmaceutical companies for preclinical and clinical development, regulatory, CMC, medical affairs, business development, financing. Experience in dozen Therapeutic areas include: Cardiovascular, Neurology, Psychiatry, Diabetes and Immune Diseases, Endocrinology, Dermatology, Inflammatory and Infectious Diseases, Metabolic Diseases, Oncology, Urology and Kidney Diseases, Women's and Men's Health Care.

2 county court Suite 400 Brampton, Ontario, L6W 3W8 CanadaPharmaffiliates is a leading Contract Research and Development Organization. We have established strategic international partnerships with the leading companies in healthcare to support our vision. We have USFDA accepted facility, ISO 9001:2008 & ISO 17025:2005 and ISO 17034 providing World Class Analytical Testing Services around the globe. Precision analytical technologies are required to assess production quality and to determine trace level impurities which may present a risk to human health or the environment. These technologies are often highly specialized analytical instruments which can only be operated by scientists who have industry application experience. We strive to work with the best in the industry. We have already set a benchmark by developing, validating and submitting over 400 methods to European and US Authorities. We empower clients ranging from emerging biotech to Top Global Pharma companies to reach confident clinical decisions that ultimately serve to improve patient lives. We are in collaboration with the best in the industry like Glenmark Pharmaceuticals, Orion, Specifar, Genepharm, Pharos , Pharmasol, Teva, DSM, Ranbaxy, Dr Reddy’s, Cipla, Zydus, Torrent, Alembic etc. to name a few. Presently we are offering a comprehensive range of analytical services using our network of state-of-the art laboratories our analytical capabilities are complemented by extensive services, e.g.: Small molecule discovery services Custom Synthesis Library Synthesis Impurity Profiling Analytical Method Development Method Validation, Method Transfer, Method Verification Stability studies Regulatory services (DMF filling, Dossier Preparation) Package Testing Product Testing Quality Assurance Quality Control USP Testing Analytical Reagents Compendial Testing Elemental Analysis Heavy Metals Analysis Technologies are calibrated to your deposit, and methods and detection limits are reviewed and validated regularly to ensure that data quality objectives are being met and maintained. Our QA/QC protocol is the backbone of the service, controlling methodology, data management and reporting, quality control and governance activities.

4770 Sheppard Avenue EastPharma Medica Research offers phase I bioequivalence studies and phase II clinical trials as well as bioanalysis, custom organic molecule synthesis of drug metabolites, and biostatistics.

6100 Belgrave RoadPharma Medica Research offers phase I bioequivalence studies and phase II clinical trials as well as bioanalysis, custom organic molecule synthesis of drug metabolites, and biostatistics.

2 Chelsea Lane Brampton, Ontario L6T 3Y4 CanadaPHARMCO-AAPER is a manufacturer of Pure and Denatured Ethanol, High Purity Chemicals and Sterile Solvents.

Markham, ON CanadaPharmEng is a full service consulting form for pharmacutical, medical device and biotechnology industries.

3760 14th Avenue Suite 201 Markham, Ontario L3R 3T7 CanadaPharmEng is a full service consulting form for pharmacutical, medical device and biotechnology industries.

110 Industrial Parkway North, Aurora Aurora, Ontario, L4G 3H4 CanadaPiramal Pharma Solutions is a Global Contract Research Development and Manufacturing Organization (CRDMO), offering end-to-end drug discovery, development and manufacturing services through our global network of 14 sites located in India, UK & North America (Canada & USA). With 350+ FTE’s the Ahmedabad, India based small molecule discovery services division has been in business since 2003 and our capabilities include: - Custom Synthesis of individual compounds, building blocks, scaffolds, focused libraries (40 to 100 compounds), reference standards, impurities & metabolites - DMPK & In-Vitro Biology - Route Scouting leveraging our global process chemistry expertise across US, Canada & India - Non-GMP scale up (up to 5kg) - Analytical services including method development (non-GMP), mg to gm scale separation of Chiral/ Achiral compounds We work on both FTE and Fee Based models. Through our global network in India and North America we offer small molecule intermediates, API development and GMP manufacturing. Our formulations capabilities include oral solids, liquids and Lyophilized product development and GMP manufacturing. We also offer specialized capabilities including antibody drug conjugation (ADC), High Potent API (HPAPI's) and Peptides GMP development and manufacturing .

268 Main Street, Suite 400, Buffalo, NY 14202 USAPraxis provides patient recruitment services.

1348 Sandhill Dr. Ancaster, ON, L4G3Z9 CanadaPrecision BioLogic is a privately-held company that develops, manufactures and markets specialized products used by medical professionals and researchers around the globe to diagnose coagulation disorders. Precision BioLogic also has several active initiatives with pharmaceutical partners who seek to ensure that the diagnostic implications for their novel therapeutic agents have been well characterized.

428-192 Spadina Ave. Toronto, ON, ON, M5T 2C2 CanadaPrivate AI specializes in advanced privacy-preserving solutions designed for Contract Research Organizations (CROs) and researchers in the clinical and life sciences industries. Our cutting-edge tools integrate seamlessly into data workflows, enabling organizations to anonymize, pseudonymize, and securely process sensitive data while ensuring compliance with stringent privacy regulations (GDPR, HIPAA, CCPA, etc.). By leveraging our AI-driven technology, research teams can maintain data utility for analytics and insights without compromising privacy. Whether it’s clinical trial data, patient records, or genomic datasets, our solutions empower researchers to innovate and collaborate confidently, mitigating privacy risks and accelerating timelines. Private AI is trusted by leading organizations worldwide to enhance compliance, data security, and research outcomes.

160 College Street, Room 1204, Toronto, Ontario, M5S 3E1 Canada

145 Konrad Crescent, Suite 11 Markham, Ontario L3R 9T9 CanadaQuality Compliance Laboratories (QCL) offers quality control testing, stability studies, method development/validation, and microbiological testing services.

101 Main Street, Suite 1720Quanticate offers clinical research services including data management, statistical consultancy/programming/analysis, medical writing, and pharmacovigilance.

4673 Downey Road Guelph, Ontario N1H 6J3Quorum Technologies Inc. is a private, Canadian owned enterprise located in Guelph, Ontario. The company develops and integrates scientific instruments and is the leading provider of technologies to support Digital Pathology, Telepathology and the Life Sciences community with over 100 of these installations across the country. Quorum dedicates over 30 years of experience integrating microscope components to meet the goals of the scientific community and holds over half a dozen patents with several others in process. Through a variety of technology transfer relationships with Canadian universities, Quorum is helping to bring new innovative technologies to market for use in preclinical research, drug development and personalized medicine.

661 University Avenue Suite 1300 Toronto, ON, M5G 1M1 CanadaVariantFind™ is a division of Ranomics that solely focuses on applying the Ranomics' Multisite Saturation Mutagenesis technology to generating comprehensive variant libraries. We are committed to providing top quality variant libraries at competitive costs with quick turn-around time.

661 University Ave Toronto, Ontario, Canada M5G 1M1 Suite 1300 Toronto, ON, M5G 1M1 CanadaVariantFind™ is a division of Ranomics that solely focuses on applying the Ranomics' Multisite Saturation Mutagenesis technology to generating comprehensive variant libraries. We are committed to providing top quality variant libraries at competitive costs with quick turn-around time.

181 Bay Street, Suite 4400 Toronto, Ontario , M5J 2T3 CanadaScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

2150 Elmwood Avenue Buffalo, NY, 14207 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

Unit 1504 88 Corporate Drive Toronto, ON, M1H 3G6 CanadaScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

545 King Street West Toronto, ON M5V 1M1 CanadaResearch Echo is a unique service provider based in Toronto, Canada specializing in clinical research management, monitoring and auditing of biotechnology and medical device studies. Our mission is to provide the client with a highly experienced quality-focused team that can carry a project from trial start to conclusion seamlessly and cost-effectively. Our competitive advantage is our make-up: a team of highly skilled CRA consultants with significant all phase trial experience. Our track record, regulatory and clinical expertise means we get it right, from the start. We love what we do and our passion is working with new companies, new compounds and innovative medical devices.

2680 Matheson Blvd. East, Suite 102 Mississauga, ON L4W 0A5 CanadaRidgewood Research is a Canadian company dedicated to providing high tech services in the areas of research and development for the pharmaceutical, food, cosmetics, and other R&D establishments.

Markham, ON CanadaRIMAX Research offers phase I-IV clinical research services including clinical trial management, project management, first in human studies, bioavailibility/bioequivalence studies, pharmacokinetics/pharmacodynamics, and drug interaction studies in the therapeutic areas of cardiology, dermatology, endocrinology, neurology, respiratory, and urology.

Carlton Street Buffalo, NY, 14203 United StatesThe RPCI Data Bank and BioRepository Shared Resource (DBBR) prospectively collects and provides de-identified biospecimens and associated epidemiological and clinical data to investigators with IRB approved protocols. Newly diagnosed patients are consented for collection of blood tubes, completion of a risk factor questionnaire, and permission to link their samples to clinical data. DBBR samples and data can also be paired with tumor tissue from the Pathology Network Shared Resource and clinical data abstraction from the Clinical Data Network Shared Resource.

Elm and Carlton Streets Buffalo, NY 14263 USARoswell Park Cancer Institute currently supports over 20 scientific shared resources that provide our investigators with access to a broad range of sophisticated scientific instrumentation, cutting edge technical and analytical applications, comprehensive sample biorepositories and more.

Buffalo, NY United StatesThe mission of the Gene Targeting and Transgenic Shared Resource (GTTR) is to ensure that investigators have access to state-of-the-art transgenic mouse technologies, methods and animal models.

Roswell Park Cancer Institute Gene Targeting and Transgenic Resource Medical Research Complex, Rooms 312A, 376, 381 and 381A Elm and Carlton Streets Buffalo, New York 14263The mission of the Gene Targeting and Transgenic Shared Resource (GTTR) is to ensure that investigators have access to state-of-the-art transgenic mouse technologies, methods and animal models.

Elm & Carlton Streets Buffalo, NY, 14263 United States

4174 Dundas Street West Suite 300SciAn Services offers phase I-IV clinical research services including trial management, site management, data management, consulting, and regulatory support.

477 Richmond St West Unit 306 Toronto, ON, M5V 3E7 CanadaSelf Care Catalysts is a patient-centered digital therapeutics, intelligence and analytics company deriving value from patient-centered real world evidence to inform clinical care, product life cycle management and behavior change interventions. Self Cate Catalysts promotes the Health Storylines platform that enables patient - centered digital trials, patient reported outcomes generated in real world, real time, over time.

6490 Vipond Drive Mississauga ,0N Canada L5T 1W8SGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

145 Konrad Crescent Markham, ON, L3R 9T9 CanadaSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

555 University Avenue Toronto, Ontario Canada M5G 1X8

Toronto, ON CanadaOur technology leverages Convolutional Neural Networks (CNNs) to automatically segment tumors, glandular, adipose and vascular tissues. This information yields a 3D representation of the patients tumor (virtual tumor) to provide greater insights for more informed decision making.By integrating spatial biophysics into our technology, our 3D models capture a tumor's physics, chemistry, and biology information at multiple scales. Every region of the tumor's chemical concentrations continually updates to reflect transport, reactions, metabolic behavior, and varying drug concentrations that affect how tumor cells respond. Our 3D mechanic models provide insights into tissues' growth or decline response. These insights play a pivotal role in guiding cancer treatment.Our technology can capture tumor biology and simulate how nutrients, chemicals, and drugs are distributed within a tumor and how this affects tumor growth or shrinkage in different regions through time.

135 Queen's Plate Drive Unit 520Our technology leverages Convolutional Neural Networks (CNNs) to automatically segment tumors, glandular, adipose and vascular tissues. This information yields a 3D representation of the patients tumor (virtual tumor) to provide greater insights for more informed decision making.By integrating spatial biophysics into our technology, our 3D models capture a tumor's physics, chemistry, and biology information at multiple scales. Every region of the tumor's chemical concentrations continually updates to reflect transport, reactions, metabolic behavior, and varying drug concentrations that affect how tumor cells respond. Our 3D mechanic models provide insights into tissues' growth or decline response. These insights play a pivotal role in guiding cancer treatment.Our technology can capture tumor biology and simulate how nutrients, chemicals, and drugs are distributed within a tumor and how this affects tumor growth or shrinkage in different regions through time.

36 Meteor Drive Toronto, ON, M9W 1A4 CanadaSQI Diagnostics supports better healthcare through faster, more accurate multiplexing technology.Specifically, we help generate more comprehensive data from single tests, using an automated process that also reduces experimental variables and handling errors. Associated services significantly reduce the time and cost of assay development. We believe you already have the ingenuity to dramatically improve quality of life. Our job is to provide the tools and services that will progress those ideas to market faster.

1380 Rodick Road Markham Toronto, ONTARIO, L3R 4G5 CanadaStandard BioTools Inc. (Nasdaq: LAB), has an established portfolio of essential, standardized next-generation technologies that help biomedical researchers develop medicines faster and better. As a leading solutions provider, the company provides reliable and repeatable insights in health and disease using its proprietary SomaScan, mass cytometry and microfluidics technologies, which help transform scientific discoveries into better patient outcomes. Standard BioTools works with leading academic, government, pharmaceutical, biotechnology, plant and animal research and clinical laboratories worldwide, focusing on the most pressing needs in translational and clinical research, including oncology, immunology and immunotherapy.

Cra 100 # 5-169 Oficina 602STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

2838 Bovaird Drive WestSunOpta provides natural products for sale as well as product formulation, custom ingredient, and quality control services.

1021 Main Street Buffalo, NY, 14203-1016 United StatesThe Research Institute on Addictions (RIA) is a long-standing national leader in the study of substance use and abuse, addiction and treatment. For more than 40 years, we have conducted groundbreaking research on significant addiction issues. Part of UB’s Downtown Campus, RIA is a key contributor to the university’s reputation for research excellence and a proud member of the Buffalo Niagara Medical Campus.

1021 Main Street Buffalo, NY , 14203-1016 United StatesThe Research Institute on Addictions (RIA) is a long-standing national leader in the study of substance use and abuse, addiction and treatment. For more than 40 years, we have conducted groundbreaking research on significant addiction issues. Part of UB’s Downtown Campus, RIA is a key contributor to the university’s reputation for research excellence and a proud member of the Buffalo Niagara Medical Campus.

285 Kapoor Hall Buffalo, NY 14214-8033Computation and visualization play a key role in our educational and research activities. We offer courses that provide a heavy concentration in quantitative disciplines, including physical pharmaceutical sciences, pharmacokinetics, pharmacodynamics, pharmacogenetics and pharmacogenomics. Specialized software holdings not only support research and education in PK/PD/PG, but also in molecular computation and visualization. Basic skills training also is offered in computation related to the practice of pharmacy. In terms of research, both undergraduate and graduate students receive hands-on research training by participating in externally-funded research projects. Analysis of data and presentation of research findings are a mainstay of research training.

285 Kapoor Hall Buffalo, NY , 14214-8033 United StatesComputation and visualization play a key role in our educational and research activities. We offer courses that provide a heavy concentration in quantitative disciplines, including physical pharmaceutical sciences, pharmacokinetics, pharmacodynamics, pharmacogenetics and pharmacogenomics. Specialized software holdings not only support research and education in PK/PD/PG, but also in molecular computation and visualization. Basic skills training also is offered in computation related to the practice of pharmacy. In terms of research, both undergraduate and graduate students receive hands-on research training by participating in externally-funded research projects. Analysis of data and presentation of research findings are a mainstay of research training.

285 Kapoor Hall Buffalo, NY, 14214-8033 United StatesComputation and visualization play a key role in our educational and research activities. We offer courses that provide a heavy concentration in quantitative disciplines, including physical pharmaceutical sciences, pharmacokinetics, pharmacodynamics, pharmacogenetics and pharmacogenomics. Specialized software holdings not only support research and education in PK/PD/PG, but also in molecular computation and visualization. Basic skills training also is offered in computation related to the practice of pharmacy. In terms of research, both undergraduate and graduate students receive hands-on research training by participating in externally-funded research projects. Analysis of data and presentation of research findings are a mainstay of research training.

12 Capen Hall, Buffalo, NY, 14260-1660 United StatesThe Pharmaceutical Genetics Laboratory (460 Kapoor Hall) provides research support for an array of basic molecular biology techniques to assist students and faculty in addressing questions in pharmacogenetics research. The laboratory has the necessary equipment to perform quantitative real-time PCR, DNA genotyping, DNA cloning, recombinant protein expression, fluorescence microscopy, and imaging. The facility provides varied equipment including real-time PCR cyclers (Bio-Rad and Stratagene), a Bio-Rad photo documentation system, nano drop spectrophotometers, a Zeiss Axiovert 200M microscope, gradient PCR thermal cyclers, refrigerated centrifuges and ultracentrifuges, dedicated -20 ºC and -80 ºC freezers, and miscellaneous equipment.

285 Kapoor Hall Buffalo, NY 14214-8033The Pharmaceutical Genetics Laboratory (460 Kapoor Hall) provides research support for an array of basic molecular biology techniques to assist students and faculty in addressing questions in pharmacogenetics research. The laboratory has the necessary equipment to perform quantitative real-time PCR, DNA genotyping, DNA cloning, recombinant protein expression, fluorescence microscopy, and imaging. The facility provides varied equipment including real-time PCR cyclers (Bio-Rad and Stratagene), a Bio-Rad photo documentation system, nano drop spectrophotometers, a Zeiss Axiovert 200M microscope, gradient PCR thermal cyclers, refrigerated centrifuges and ultracentrifuges, dedicated -20 ºC and -80 ºC freezers, and miscellaneous equipment.

12 Capen Hall, Buffalo, New York, 14260-1660 United StatesThe Pharmaceutical Genetics Laboratory (460 Kapoor Hall) provides research support for an array of basic molecular biology techniques to assist students and faculty in addressing questions in pharmacogenetics research. The laboratory has the necessary equipment to perform quantitative real-time PCR, DNA genotyping, DNA cloning, recombinant protein expression, fluorescence microscopy, and imaging. The facility provides varied equipment including real-time PCR cyclers (Bio-Rad and Stratagene), a Bio-Rad photo documentation system, nano drop spectrophotometers, a Zeiss Axiovert 200M microscope, gradient PCR thermal cyclers, refrigerated centrifuges and ultracentrifuges, dedicated -20 ºC and -80 ºC freezers, and miscellaneous equipment.

285 Kapoor Hall Buffalo, NY, 14214 United StatesThe Pharmaceutical Sciences Instrumentation Facility is available to all School of Pharmacy and Pharmaceutical Sciences faculty. It connects to faculty laboratories, conference rooms, glass washing room and walk-in cold room. Instrumentation Facility includes: liquid chromatography/mass spectrophometers ultracentrifuges scintillation counters gamma counter high performance liquid chromatographs spectrophotometers, including gas chromatographs, physiographs computer-aided imaging equipment cell culture facilities fluorescent and uv/visible plate readers phosphoimager peptide synthesizer, fluorescence and circular dichroism spectrometers differential scanning calorimetry thermogravimetric and analysis instrumentation

285 Kapoor Hall Buffalo, NY 14214-8033The Pharmaceutical Sciences Instrumentation Facility is available to all School of Pharmacy and Pharmaceutical Sciences faculty. It connects to faculty laboratories, conference rooms, glass washing room and walk-in cold room. Instrumentation Facility includes: liquid chromatography/mass spectrophometers ultracentrifuges scintillation counters gamma counter high performance liquid chromatographs spectrophotometers, including gas chromatographs, physiographs computer-aided imaging equipment cell culture facilities fluorescent and uv/visible plate readers phosphoimager peptide synthesizer, fluorescence and circular dichroism spectrometers differential scanning calorimetry thermogravimetric and analysis instrumentation

12 Capen Hall, Buffalo, New York , 14260-1660 United StatesThe South Campus Instrument Center (SCIC) is a full-service facility that specializes in surface imaging and spectroscopy for a wide range of materials and products, as well as expertise in product quality assurance testing, failure analysis, and forensic evaluations. You are encouraged to work directly with our staff for your materials analysis needs. We are also available to visit your production sites to collect samples and additional information, if required.

240 Richmond Street West Toronto, ON, M5V 2C5 CanadaWe are a small group of highly experienced researchers with international backgrounds in academia, government and industry. Our deep knowledge and nimble approach allows us to meet your needs with flexibility, technical excellence, timeliness and good humour. We take pride in our work and we get results. We are experts in achieving reimbursement for pharmaceuticals and devices in countries around the world, and communicating value in healthcare to diverse audiences.

50 Viceroy Road Unit 7 Concord, Ontario, L4K 3A7 CanadaSynthose is a premier manufacturer of carbohydrates and glycoconjugates. We specialize in the synthesis of natural glycosides, drug metabolites, orthogonally protected building blocks, and the stable labelling of sugars. We currently have a catalogue of over 900 chemicals, and we are releasing new products each week in line with the latest research of our customers. With thousands of available intermediates and over ten years in development of synthetic routes towards sugars, our scientific team can quickly deliver the compound you need for your project.

640 Ellicott Street Buffalo, NY, 14203 United StatesTartis, Inc. is a discovery stage biotechnology company seeking novel anti-cancer and anti-aging drugs. Its proprietary technology is licensed from the laboratories of Professor Gudkov from Roswell Park Cancer Institute (Buffalo, NY). Tartis, Inc. pipeline includes lead compounds for treatment of breast and prostate cancers, melanoma and hematological malignancies, as well as leads and drug candidates for delaying the development of age-related diseases (including cancer) and prolonging human life.

640 Ellicott St., Suite 444 Buffalo, NY 14203Tartis, Inc. is a discovery stage biotechnology company seeking novel anti-cancer and anti-aging drugs. Its proprietary technology is licensed from the laboratories of Professor Gudkov from Roswell Park Cancer Institute (Buffalo, NY). Tartis, Inc. pipeline includes lead compounds for treatment of breast and prostate cancers, melanoma and hematological malignancies, as well as leads and drug candidates for delaying the development of age-related diseases (including cancer) and prolonging human life.

686 Bay Street, Room 139800 Toronto, Ontario M5G 0A4, CanadaTCAG at The Hospital for Sick Children Biobanking and Databasing Facility provides DNA extraction from lymphoblasts, fibroblasts and other cell types, archiving of white cell pellets, preparation and immortalization of cell lines, and comprehensive databasing and tracking of samples and/or cell lines within the facility.

686 Bay Street, Room 139800 Toronto, Ontario M5G 0A4, CanadaTCAG at The Hospital for Sick Children Microarray Analysis and Gene Expression Facility offers a comprehensive set of microarray based services to researchers in the academic, commercial and pharmaceutical communities.

Toronto, ON CanadaTCAG at The Hospital for Sick Children Microarray Analysis and Gene Expression Facility offers a comprehensive set of microarray based services to researchers in the academic, commercial and pharmaceutical communities.

375 Main Street, Suite# 201Tech Observer offers their expertise in Clinical Monitoring, Clinical Data Management, Statistical/SAS Analyses, Scientific Communication, Pharmacovigilance and Regulatory Affairs.

330 Nantucket Boulevard Toronto, ON M1P 2P4 CanadaTekran® was founded in Toronto, Canada in 1989 to develop custom analytical instrumentation for environmental analysis. Our first analyzer, the Tekran® 2537, was introduced in 1993 and is now widely accepted as the gold standard for automated ambient air analysis of mercury. Tekran® continues to expand and improve our product lines, which are focused exclusively on instruments and systems for mercury measurement. We now offer systems for ambient air mercury speciation monitoring, automated analysis of total mercury and methyl mercury in environmental samples, total mercury in natural gas, and mercury continuous emission monitoring of coal-fired power plants and other industrial emission sources. We also offer a wide range of secondary equipment to support our main product lines.

330 Nantucket Boulevard Toronto, ON, M1P 2P4 CanadaTekran® was founded in Toronto, Canada in 1989 to develop custom analytical instrumentation for environmental analysis. Our first analyzer, the Tekran® 2537, was introduced in 1993 and is now widely accepted as the gold standard for automated ambient air analysis of mercury. Tekran® continues to expand and improve our product lines, which are focused exclusively on instruments and systems for mercury measurement. We now offer systems for ambient air mercury speciation monitoring, automated analysis of total mercury and methyl mercury in environmental samples, total mercury in natural gas, and mercury continuous emission monitoring of coal-fired power plants and other industrial emission sources. We also offer a wide range of secondary equipment to support our main product lines.

Toronto, ON CanadaThe Centre for Applied Genomics at The Hospital for Sick Children offers microarray, cytogenomic, biobanking, and sequencing services.

25 Orde Street Toronto, ON, M5T 3H7 CanadaThe strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide: - Custom services for the generation of genetically engineered mouse models - Mouse holding and technical services for preclinical in vivo research projects - Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation - Biorepository services to archive, acquire, and distribute mouse models

25 Orde StreetThe strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide: - Custom services for the generation of genetically engineered mouse models - Mouse holding and technical services for preclinical in vivo research projects - Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation - Biorepository services to archive, acquire, and distribute mouse models

25 Orde St. Toronto, Ontario, M5T 3H7 CanadaThe strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide: - Custom services for the generation of genetically engineered mouse models - Mouse holding and technical services for preclinical in vivo research projects - Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation - Biorepository services to archive, acquire, and distribute mouse models

Mississauga,The Clinical Trial Company offers clinical research services including project management, regulatory affairs, clinical and preclinical studies, and safety/efficacy studies with expertise in gene therapy, cardiology, hematology, dermatology, urology, oncology, endocrinology, immunology, respiratory, CNS, and ophthalmology.

1280 Main Street West Hamilton, ON, L8S 4L8 CanadaTo provide a variety of spectroscopic techniques for sample analyses, and is made available to the Department, the University, and other academic, government,or industrial laboratories.

2655 North Sheridan Way Suite 120 Mississauga, ON L5K 2P8 CanadaTheorem Clinical Research offers full service clinical research solutions including DM, biostatistics, programming including CDISC, PM, clinical operations, and regulatory affairs.

2585 Meadowpine BoulevardTherapure Biopharma provides biomanufacturing solutions and drug development.

2-70 Villarboit CrescentTLC PharmaChem specializes in custom synthesis of complex organic chemicals for biomedical and pharmaceutical research.

48 George Street Aurora Ontario L4G 2S2 CanadaTorealis offers management of various stages of clinical research and pharmaceutical development.

Aurora, ON CanadaTorealis offers management of various stages of clinical research and pharmaceutical development.

200 Elizabeth Street Toronto, ON , M5G 2C4 CanadaToronto General Hospital (TGH) is one of Toronto’s oldest hospitals, dating back to 1819 when the Loyal and Patriotic Society of Upper Canada organized a trust fund to support the construction and maintenance of a hospital in the provincial capital, the Town of York. Construction began in 1820 and the General Hospital of the Town of York was opened for patients in June 1829 at Simcoe and King Streets. As Toronto General, it expanded to Gerrard and Sumach in 1856 and then to College Street in 1913. The College Street location has since become the MaRS building, while Toronto General has spread out south along University Avenue. Among its world firsts, TGH performed the world’s first successful single lung transplant in 1983, followed by the first double-lung transplant in 1986. In 1950, the first external heart pacemaker was used in an open-heart resuscitation. And in 1922, insulin was developed and saw its first clinical use in the treatment of diabetes on a young patient at TGH.​​​

200 Elizabeth Street Toronto, ON, M5G 2C4 CanadaToronto General Hospital (TGH) is one of Toronto’s oldest hospitals, dating back to 1819 when the Loyal and Patriotic Society of Upper Canada organized a trust fund to support the construction and maintenance of a hospital in the provincial capital, the Town of York. Construction began in 1820 and the General Hospital of the Town of York was opened for patients in June 1829 at Simcoe and King Streets. As Toronto General, it expanded to Gerrard and Sumach in 1856 and then to College Street in 1913. The College Street location has since become the MaRS building, while Toronto General has spread out south along University Avenue. Among its world firsts, TGH performed the world’s first successful single lung transplant in 1983, followed by the first double-lung transplant in 1986. In 1950, the first external heart pacemaker was used in an open-heart resuscitation. And in 1922, insulin was developed and saw its first clinical use in the treatment of diabetes on a young patient at TGH.​​​

399 Bathurst Street Toronto, ON, M5T 2S8 CanadaToronto Western Hospital is located in the vibrant heart of the downtown communities of South Annex, College, Queen and King Street West. It is a 272-bed academic health science centre dedicated to delivering exceptional patient care, providing a breadth of services from emergency care to sophisticated brain surgery. As a world leader in neuroscience, TWH is constantly pushing the boundaries of research, offering pioneering treatments and using state-of-the-art technology. The hospital also has a strong community focus, providing innovative programs for and information to children, seniors, diabetes patients and many multicultural groups. With expertise in musculoskeletal health and arthritis, the hospital's programs also include orthopaedics, rheumatology and the hand program as well as a busy Emergency Department that sees more than 60,000 patients yearly.

399 Bathurst Street Toronto, ON , M5T 2S8 CanadaToronto Western Hospital is located in the vibrant heart of the downtown communities of South Annex, College, Queen and King Street West. It is a 272-bed academic health science centre dedicated to delivering exceptional patient care, providing a breadth of services from emergency care to sophisticated brain surgery. As a world leader in neuroscience, TWH is constantly pushing the boundaries of research, offering pioneering treatments and using state-of-the-art technology. The hospital also has a strong community focus, providing innovative programs for and information to children, seniors, diabetes patients and many multicultural groups. With expertise in musculoskeletal health and arthritis, the hospital's programs also include orthopaedics, rheumatology and the hand program as well as a busy Emergency Department that sees more than 60,000 patients yearly.

D-Mark Biosciences 35 Grand Marshall Drive Toronto, ON M1B 5W9 CanadaTransomic offers next generation genomic tools and genomic services to life science researchers. We have whole genome arrayed CRISPR, shRNA, and cDNA libraries all in house. All clones are sequence verified. Custom offerings: • CRISPR and shRNA screening pools delivered as ready to us high titer lentiviral particles. Screening pools are created from our in-house libraries or we can custom synthesize oligo pools and clone into large selections of lentiviral vectors. All screening pools go through NGS to ensure equal representation. • Custom screening services including NGS and analysis • Gene synthesis and cloning into a large selection of lentiviral vectors • Stable cell line production • Lentiviral packaging services • 96-well DNA prep services

P.O. Box 248 Fergus Fergus, ON, N1M 2W8 CanadaTranspharmation provides translational pre-clinical and clinical pharmacology services to the pharmaceutical and biotechnology industry, with the aim of better understanding potential new medicines as they transition into the clinic.

P.O. Box 248 Fergus Ontario, N1M 2W8 CanadaTranspharmation provides translational pre-clinical and clinical pharmacology services to the pharmaceutical and biotechnology industry, with the aim of better understanding potential new medicines as they transition into the clinic.

60 St. Clair Avenue East, Suite 702Trial Management Group offers phase II-IV clinical research services for many therapeutic areas.

110 Cumberland St., Suite 406 Toronto, ON, M5R 3V5 CanadaConvenient, reliable and cost effective research and development services the life scientists trust and rely on.

3850 Finch Ave E #306 Scarborough, ON, M1T 3T6 CanadaConvenient, reliable and cost effective research and development services the life scientists trust and rely on.

96 Skyway Avenue Toronto, ON, M9W 4Y9 CanadaTrillium Therapeutics Inc. (TTI) is a privately-owned biopharmaceutical company with two main areas of focus: cytoprotection and immune regulation. The Company's cytoprotection programs are based upon a recombinant form of heparin-binding epidermal growth factor-like growth factor (HB-EGF).

1237 Delaware Avenue Buffalo, NY 14209 USAUniversity at Buffalo Next-Generation Sequencing and Expression Analysis Core (UB Next-Gen Core) offers next generation sequencing services with the use of Affymetrix, Illumina and Roche platforms.

Buffalo, NY United StatesUniversity at Buffalo Next-Generation Sequencing and Expression Analysis Core (UB Next-Gen Core) offers next generation sequencing services with the use of Affymetrix, Illumina and Roche platforms.

17-689 Warden Ave Toronto, Ontario, M1L 4R6 CanadauFluidix produces microfluidic devices. We provide large volume manufacturing of Microfluidic chips as well as custom fabrication of low-medium volume microfluidic platforms. Microfluidics technology is used to process nano-micro litere amount of fluid inside microchannels in the microfluidic device.

170 College Street Toronto, Ontario, M5S3E3 CanadaProviding sample prep and imaging services for SEM, TEM and cryoEM.

51 Gillespie Ave Toronto, On, M6N2Y5 CanadaProviding sample prep and imaging services for SEM, TEM and cryoEM.

6351 Inducon Drive East Sanborn, NY 14132 USAUnited Biochemicals specializes in liquid and chemical manufacturing, product management, and laboratory testing services.

Unit 10 - 1085 Bellamy Road NorthUnited Bioscience Canada Corporation (UBCC) is a high quality provider of Hyaluronic Acid using an exclusive fermentation technology as opposed to traditional methods of production.

2355 Derry Road East Mississauga, ON, L5S 1V6 CanadaUQSI is a US based international team of Pharmaceutical Consultants providing a wide range of consulting services to Pharmaceutical, Biotechnology and Active Pharmaceutical Ingredients (APIs) Industry. Our team of professionals can provide operational assistance in Quality functions, Commissioning & Qualification, Validation, cGMP Compliance, Regulatory Affairs, design and construction supervision for new plants. Our team is well experienced to meet your immediate and long term requirements of skilled biotech and pharma science trained, experienced staff.

190 Elizabeth Street R Frasier Elliot Building Toronto, ON, M5G 2C4 CanadaUHN Research is Canada's largest research hospital with a proud history of innovative research and discoveries. UHN Research enterprise is rooted in a robust and efficient infrastructure that has enabled the organization to achieve worldwide recognition. Through a comprehensive suite of services, UHN Research is enabling academic, clinical, and industry clients to access UHN Research's integrated resources, state-of-the-art instruments, and innovative technologies to support a multitude of research studies.

101 College Street, Suite 150 Heritage Building, MaRS Centre Toronto, Ontario, M5G 1L7 CanadaUHN Research is Canada's largest research hospital with a proud history of innovative research and discoveries. UHN Research enterprise is rooted in a robust and efficient infrastructure that has enabled the organization to achieve worldwide recognition. Through a comprehensive suite of services, UHN Research is enabling academic, clinical, and industry clients to access UHN Research's integrated resources, state-of-the-art instruments, and innovative technologies to support a multitude of research studies.

University of Toronto 160 College Street, Room 230 Toronto, Ontario, M5S 3E1 CanadaIn the late 90s, there was no human genome sequence, no wide-spread stem cell technologies, and DNA sequencing was slow and expensive. However, University of Toronto Professors Cecil Yip and James Friesen foresaw that new genomic technologies would open up massive progress in biomedical research. Anticipating the growing need for interdisciplinary approaches, they envisioned a research institute where all boundaries in research could be lifted. Thanks to an investment from the Government of Canada, the province of Ontario, private sector companies and Terrence J. Donnelly, a philanthropist with a vision, that revolutionary idea materialized into a world-renowned institute for biomedical research – the Donnelly Centre. On November 5, 2005 the Donnelly Centre for Cellular and Biomolecular Research opened its doors to world-class researchers in biology, computer science, engineering, chemistry and pharmacy under one joint roof, where they could feed off each other’s expertise and creativity to decipher the biology behind the world's most devastating diseases.

160 College Street Toronto, ON, M5S 3E2 CanadaIn the late 90s, there was no human genome sequence, no wide-spread stem cell technologies, and DNA sequencing was slow and expensive. However, University of Toronto Professors Cecil Yip and James Friesen foresaw that new genomic technologies would open up massive progress in biomedical research. Anticipating the growing need for interdisciplinary approaches, they envisioned a research institute where all boundaries in research could be lifted. Thanks to an investment from the Government of Canada, the province of Ontario, private sector companies and Terrence J. Donnelly, a philanthropist with a vision, that revolutionary idea materialized into a world-renowned institute for biomedical research – the Donnelly Centre. On November 5, 2005 the Donnelly Centre for Cellular and Biomolecular Research opened its doors to world-class researchers in biology, computer science, engineering, chemistry and pharmacy under one joint roof, where they could feed off each other’s expertise and creativity to decipher the biology behind the world's most devastating diseases.

2075 Bayview Avenue, M7 109 Toronto, ON, M4N 3M5 CanadaThe advanced machine shop is part of the device development lab within the Centre for Research in Image-Guided Therapeutics at Sunnybrook Research Institute. It is a state-of-the-art facility equipped for the design, fabrication and testing of medical devices. It specializes in the manufacture of magnetic resonance imaging-compatible devices, prototypes, custom-made parts and catheter-based devices, and in 3-D computer-assisted design. The technicians within the facility are capable of working from drawings, hand sketches or ideas in one's head, and can help transform a concept into a working prototype. Materials used in the facility include aluminum, stainless steel, plastics, brass, wood and exotic materials. The facility is equipped with a computer numerical controlled lathe and mill, five-axis waterjet cutter, rapid prototypers (stereolithography and fused deposition modeling technology in a variety of materials), manual lathes, manual mills, hydraulic shear, bender, table saw, router and bead blaster. The machines and services of technicians are available to users within Sunnybrook Research Institute, the hospital, external academic institutions and industrial clients at competitive rates. In addition to fabricating parts, the facility performs testing and characterization of medical imaging systems in partnership with Sunnybrook Research Institute scientists.

2075 Bayview Avenue, A3 38 Toronto, ON, M4N 3M5 CanadaThe antibody core facility purifies by affinity chromatography antibodies specific for cell differentiation markers, signalling and tagging molecules of various species. We conjugate these antibodies to various fluorochromes (fluorescein, allophycocyanin, phycoerythrin, and up to 20 different Alexa Fluor dyes), to biotin, and to microbeads for cell surface multicolour immunofluorescence, immunohistochemistry, functional assays and biochemical analyses. Following purification and conjugation of an antibody, the optimal titer for various applications is determined. Aside from antibodies, the facility also produces other reagents needed for various molecular biology techniques. Please contact Philippe Poussier for more information.

2075 Bayview Avenue, M7 301 Toronto, ON, M4N 3M5 CanadaThe Centre for Flow Cytometry and Microscopy at Sunnybrook Research Institute (SRI) houses two BD multilaser, digital, high-velocity cell sorters. We offer the following services: cell sorting cell analysis user training for the flow cytometer benchtop analyzers user training for the widefield and confocal microscopes Work is performed on a fee-for-service basis, and is available to internal and external users.

2075 Bayview Avenue, M6 603 Toronto, ON, M4N 3M5 CanadaSunnybrook Research Institute’s Toshiba Aquilion One computed tomography (CT) scanner is a state-of-the-art imaging system used to evaluate structure and function within the human body and animal models. Research at this facility involves development of the basic physics and engineering underlying CT technology, and includes clinically motivated imaging studies involving volunteers and preclinical studies that enhance knowledge toward improving health care. The facility accommodates a wide variety of scientific projects, usually performed in collaboration with SRI investigators. It operates on a cost-recovery basis through the collection of user fees. Research at this facility is predominately conducted by researchers in Physical Sciences and their collaborators. There are also a smaller number of CT users who use the facility independent of Physical Sciences collaborations, or in their role as support personnel in the labs of collaborating scientists. Users must meet the CT research operator training requirements.

2075 Bayview Avenue, M7 122 Toronto, ON, M4N 3M5 CanadaThe capacity to create novel devices is a cornerstone of medical innovation. In Sunnybrook Research Institute's device development laboratory—Canada's first of this scope based in a hospital—scientists and engineers are designing and producing complex medical devices under highly controlled conditions. The overarching aim is to design more effective and safer ways to detect disease, deliver therapy and guide interventions. Devices are then tested for proof of principle and, if successful, clinically, in collaboration with other researchers and clinicians. Ultimately, our aim is to commercialize the devices we invent, so we can move them into the medical marketplace to benefit patients. Main goals are as follows: To accelerate development of clinically relevant medical devices for large-scale or orphan applications To design, fabricate, test and validate candidate devices efficiently To create a centre of expertise for teaching skills related to device development, preclinical testing and validation To provide facilities and expertise that enable commercialization of new devices

2075 Bayview Avenue, C7 35c Toronto, ON, M4N 3M5 CanadaThe quality, speed and cost of generating and analyzing genomic data is increasingly crucial to researchers as they seek to develop personalized treatments for complex diseases like cancer and heart disease. The genomics core facility at Sunnybrook Research Institute (SRI), under the directorship of Dr. Arun Seth, makes cutting-edge genomics research not only possible, but also affordable. The genomics core facility is a centralized resource equipped with a range of next-generation instruments. Next-generation DNA sequencing: SOLiD 5500XL Ion Torrent Personal Genome Machine Nucleic acid quantification: Digital Droplet PCR system Real-time PCR system We deliver cost-effective and high-quality services and are continually updating and expanding our services to keep up with advances in technology and its applications. Our facility is open to the SRI community as well as to investigators from external institutions. We also provide opportunities for SRI research fellows, graduate students and residents to gain experience and training. We encourage collaborative opportunities with investigators on research projects and support investigators' grant applications.

2075 Bayview Avenue Toronto, ON, M4N 3M5 CanadaIn this facility, research teams are making new biological agents for cell-based therapies and vaccines that target dysfunctional immune systems, heart disease and cancer. Having immediate access to this strictly controlled environment ensures that quality is built into each step of the cell design and manufacturing process. This guarantees that products developed in the lab are safe, pure and effective for clinical testing. Building this lab will help move preclinical findings—such as the landmark discovery by Dr. Juan Carlos Zúñiga-Pflücker of how to generate stem cells in the lab, and coax them into becoming mature T cells, toward rebuilding damaged immune systems—faster and more efficiently to the clinic. Sunnybrook Research Institute is at the forefront of inventing methods and technologies to generate new cell types from stem cells or other stem-cell-like cells, and to re-educate cells. With this facility, we are taking it up a significant notch; our biological scientists, who are developing preclinical models, are working with clinicians-scientists, who can test the efficacy of these models in patients. Similarly, imaging scientists who have developed ways to track and evaluate the efficacy of these cells in preclinical models are interacting with clinician-scientists to track and evaluate the efficacy of these cell therapies in patients. In each case, the cGMP lab is an essential step in the translational research process.

2075 Bayview Avenue, M7 231 Toronto, ON, M4N 3M5 CanadaThe High-Content Cellular Analysis (HiCCA) lab at Sunnybrook Research Institute (SRI) is a hub for automation and fluorescence applications. Directed by Dr. David Andrews, the HiCCA lab provides platforms for high-throughput and high-content investigations of in vitro model systems, and features custom-designed instrumentation and cutting-edge technologies unique to SRI. The HiCCA lab provides the tools and expertise necessary for research programs at the level of a screen, cell or molecule. Services include high-throughput confocal and widefield microscopy, fluorescence spectrophotometry, and robotics for automated workflows. Solutions offered may be full service or else involve various degrees of collaborative effort, tailored to the needs of each specific project. User training for select instrumentation is available.

2075 Bayview Avenue, S4 408 Toronto, ON, M4N 3M5 CanadaThe histology facility at Sunnybrook Research Institute (SRI) is a full-service support lab that provides histology services for SRI researchers and external customers. It is equipped with an automated tissue processor, autostainer, embedding station, motorized microtome, cryomicrotome and vibratome. It offers paraffin services to the SRI community as well as to investigators from external institutions. Services include the following: processing decalcification paraffin embedding sectioning routine staining special staining cryosectioning vibratoming

Toronto, ON, M5S 3G9 CanadaThe Institute of Biomaterials & Biomedical Engineering (IBBME) at the University of Toronto is a unique, multidisciplinary research unit where investigators from engineering, medicine and dentistry collaborate to find innovative solutions for the world’s most pressing health-care challenges.

Medical Science Building 1 King's College Circle, Room 1239 Toronto, Ontario, M5S 1A8 CanadaThe Microscopy Imaging Laboratory (MIL) is a core imaging service in the Temerty Faculty of Medicine at the University of Toronto providing electron microscopy and fluorescence microscopy imaging capabilities to students and scientists in basic, medical and industrial research. The MIL maintains a complete lab for the preparation of TEM and SEM samples including fixation, resin embedding, thin sectioning, critical point drying and gold sputter coating. The thin sectioning lab is equipped with an RMC MT7000 and two Reichert Ultracut E ultra-microtomes. A server/workstation lab is equipped with BitPlane, AutoQuant and Zen image analysis software. Operation of the unit is on a fee for service basis. Users can take advantage of full service (all work carried out by staff in the unit) or may be trained to use the equipment themselves on an hourly or annual contract fee basis.

Toronto, ON CanadaUniv. of Toronto Department of Anesthesia focuses on research.

Toronto, ON CanadaUniversity of Toronto Service Crystallography Laboratory offers X-ray crystallography services.

Dept. of Chemistry, University of TorontoUniversity of Toronto Service Crystallography Laboratory offers X-ray crystallography services.

1909 Maple Manor Road ON, N0B CanadaIn 1989 Vaughn Agricultural Research Services Ltd. (VARS) began operations to provide independent research services to the crop protection industry. Since then, we have conducted trials for over forty Canadian and international companies. These trials have contributed to the successful registration and launch of over fifty new active ingredients into the extensive Canadian market. We have grown by providing and increasing our range of precise, reliable and innovative research and development services. These services are designed to meet strict controls and guidelines, employing the latest technologies and scientific advances. Why? Because you don’t need registration problems. You need solutions - Solutions that Register™.

3495 Bailey Avenue Buffalo, NY 14215VA Western New York Healthcare System (VAWNYHS), part of VA Health Care Upstate New York (VISN 2), consists of two health care facilities in Buffalo and Batavia, as well as community based outpatient clinics in Dunkirk, Jamestown, Lackawanna, Lockport, Niagara Falls, Olean and Springville. The Buffalo VA Medical Center opened in 1950 and provides medical, surgical, mental health and long term care services through a range of inpatient and outpatient programs. It is the main referral center for cardiac surgery, cardiology and comprehensive cancer care for central and western New York and northern Pennsylvania. The Batavia facility opened its doors in 1933. It provides geriatric and rehabilitation services, separate residential post traumatic stress disorder units for men and women, and outpatient services. In 1995, a New York State Veterans Home was built on the Batavia grounds making additional extended care available. VAWNYHS is academically affiliated with the State University of New York (SUNY) at Buffalo along with 66 additional universities and professional schools in biomedical sciences, audiology, dentistry, dietetics, health care administration, medicine, nursing, nurse anesthesia, occupational and physical therapy, pharmacy, psychology, speech pathology, and social work.

3495 Bailey Avenue Buffalo, NY, 14215 United StatesVA Western New York Healthcare System (VAWNYHS), part of VA Health Care Upstate New York (VISN 2), consists of two health care facilities in Buffalo and Batavia, as well as community based outpatient clinics in Dunkirk, Jamestown, Lackawanna, Lockport, Niagara Falls, Olean and Springville. The Buffalo VA Medical Center opened in 1950 and provides medical, surgical, mental health and long term care services through a range of inpatient and outpatient programs. It is the main referral center for cardiac surgery, cardiology and comprehensive cancer care for central and western New York and northern Pennsylvania. The Batavia facility opened its doors in 1933. It provides geriatric and rehabilitation services, separate residential post traumatic stress disorder units for men and women, and outpatient services. In 1995, a New York State Veterans Home was built on the Batavia grounds making additional extended care available. VAWNYHS is academically affiliated with the State University of New York (SUNY) at Buffalo along with 66 additional universities and professional schools in biomedical sciences, audiology, dentistry, dietetics, health care administration, medicine, nursing, nurse anesthesia, occupational and physical therapy, pharmacy, psychology, speech pathology, and social work.

61 Stonehenge Crescent Toronto, ON, M1G 2P5 Canada

102, 334Donalnds Avenue, Toronto, ON M4J3R9, Canada Canada Toronto, ON, M4J3R9 Canada

585 University Avenue Toronto, ON USAVeritas Therapeutics specializes in commercialization for the Toronto Transplant Institute and offers scientific development for immunology, biodevelopment, protein expression/purification, analytical chemistry, autoimmune disease, and animal models of disease.

14, 45 Dalkeith Dr. Brantford, ON N3P 1M1 CanadaVibrant Pharma offers a full range of services in custom organic synthesis, process development, route scouting and selection, building blocks, kinase focused libraries, heterocyclic building blocks, nucleosides and nucleoside phosphoramidites, prodrug synthesis, polymorph screening and stability studies of API and intermediates.

120 Carlton Street, Toronto, ON M5A 4K2, CACanCog is a contract research organization providing non-invasive research and development services in the companion animal market. For over 10 years, the world’s leading veterinary medicine and pet food developers have trusted CanCog scientists to help guide and conduct innovative research, from early proof-of-concept evaluations through to planning and executing full scale clinical studies. CanCog research services help generate the scientific evidence needed to support product claims and regulatory submissions. CanCog scientists and veterinarians are leading experts in the field of cognition and general behavior, anxiety, aging and life-span development. Cancog is also uniquely equipped to evaluate products for osteoarthritis, cancer and metabolic disorders, and can empower studies with state-of-the-art imaging capabilities including MRI, PET/CT and DEXA. CanCog's mission is to help evaluate and develop innovative products which improve the quality of life of companion dogs and cats. We invite you to learn more about how CanCog services can help you successfully develop your next product.

400 Iroquois Shore Road Oakville, ON, L6H 1M5 CanadaWellSpring Pharma Services (www.wellspringcmo.com) provides turn-key services for small to mid-sized pharmaceutical companies to manufacture and package their solid, semi-solid, and non-sterile liquid products at our cGMP, FDA and HC inspected facility based near Toronto. We offer fast, flexible, and concierge manufacturing services from late clinical to commercial scale.

610 Ford Drive, Suite 101, Oakville, Ontario, Canada L6J 7W4White Owl Global Services provides consulting services for the pharmaceutical, biotechnology and nutritional health industries.

2 Bloor Street West Suite 700 Toronto M4W 3R1In working with WilsonHCG as your recruitment outsourcing company, expect a full-service recruitment process experience like no other.

50 Ronson DriveAxela provides automated microarray system for hybridation, detection, reporting, and multiplex test services.

Outreach Health Services 16945 Leslie Street Unit #8 Newmarket, Ontario L3Y 9A2

ReproMed 56 Aberfoyle Crescent Suite 300 Toronto, Ontario, M8X 2W4

CAN-AM Cryoservices 1057 Main St. W. Suite 102 Hamilton, Ontario, L8S 1B7

101 College St, Ste 700 Toronto, Ontario, M5G 1L7 CanadaYCharOS Inc. is a Canadian, public interest, open science company with the mission of characterizing commercially available reagent antibodies for every human protein.

175 Longwood Rd South Hamilton, Ontario, L8P 0A1 CanadaYordas Group is a leading provider of scientific, environmental, human health, global regulatory, sustainability and product stewardship consulting services. Yordas has a solid and internationally recognised reputation as a provider of training, advice and services to ensure compliance across the globe, with regional representation and service providers in Europe, the Americas and Asia Pacific.

8 Aintree Crt Etobicoke, Ontario, M8W 2E2 Canadahealth, lifestyle and pharmaceutical market research and strategy

49 National Pine Dr. Toronto, ON L6A 3M3 CanadaZL Interpharm specializes in anesthetics, vaccines, fluorochemicals, disinfection, and water purification products.