Os Agriños, GA, 36859 SpainAgrinos is a biological crop input provider committed to improving the productivity and sustainability of modern agriculture. Agrinos’ range of High Yield Technology (“HYT”) products helps farmers to practice profitable agriculture by providing increased crop productivity, improved efficiency of conventional fertilizer and a reduced environmental footprint. Agrinos holds a leading position within the bio-stimulant segment and plans to continue its growth strategy and global efforts, driving technology adoption and crops yield around the world.

Barcelona, CT SpainAntibody BCN offers antibody services, peptide synthesis, conjugations, and recombinant proteins.

AbBcn S.L. Av. Diagonal, 392, 3º 1ª 08037 BarcelonaAntibody BCN offers antibody services, peptide synthesis, conjugations, and recombinant proteins.

Carretera M-300 km 29,920 Apartado de Correos 37 28802 Alcalá de Henares (Madrid)Alcalà Farma provides the service of comprehensive development and manufacturing of a new product

Travessera de Gràcia 108, Entl Barcelona 08012 SpainAromics provides genomic and proteomics for preclinical and clinical evaluations of drugs.

Carrer de la Llum 2-26 Cerdanyola del Valles, Barcelona, 08290 SpainALBA is a 3rd generation Synchrotron Light facility located in Cerdanyola del Vallès, (Barcelona), being the newest source in the Mediterranean area. It is a complex of electron accelerators to produce synchrotron light, which allows the visualization of the atomic structure of matter as well as the study of its properties. The 3 GeV electron beam energy at ALBA is achieved by combining a LInear ACcelerator (LINAC) and a low-emittance, full-energy BOOSTER placed in the same tunnel as the STORAGE RING. ALBA's 270 meter perimeter has 17 straight sections all of which are available for the installation of insertion devices. ALBA currently has eight operational state-of-the-art beamlines, comprising soft and hard X-rays, which are devoted mainly to biosciences, condensed matter (magnetic and electronic properties, nanoscience) and materials science. Additionally, four beamlines are in construction (low-energy ultra-high-resolution angular photoemission for complex materials, microfocus for macromolecular crystallography, absorption and diffraction and fast X-ray tomography & radioscopy). This large scientific infrastructure provides more than 6.000 hours of beam time per year and is available for the academic and the industrial sector, serving more than 2.000 researchers every year. Since as early as 2012, ALBA has been hosting official users, 65% from Spanish institutions and 35% from other countries.

Carrer de la Llum 2-26 Cerdanyola del Valles, 08290 SpainALBA is a 3rd generation Synchrotron Light facility located in Cerdanyola del Vallès, (Barcelona), being the newest source in the Mediterranean area. It is a complex of electron accelerators to produce synchrotron light, which allows the visualization of the atomic structure of matter as well as the study of its properties. The 3 GeV electron beam energy at ALBA is achieved by combining a LInear ACcelerator (LINAC) and a low-emittance, full-energy BOOSTER placed in the same tunnel as the STORAGE RING. ALBA's 270 meter perimeter has 17 straight sections all of which are available for the installation of insertion devices. ALBA currently has eight operational state-of-the-art beamlines, comprising soft and hard X-rays, which are devoted mainly to biosciences, condensed matter (magnetic and electronic properties, nanoscience) and materials science. Additionally, four beamlines are in construction (low-energy ultra-high-resolution angular photoemission for complex materials, microfocus for macromolecular crystallography, absorption and diffraction and fast X-ray tomography & radioscopy). This large scientific infrastructure provides more than 6.000 hours of beam time per year and is available for the academic and the industrial sector, serving more than 2.000 researchers every year. Since as early as 2012, ALBA has been hosting official users, 65% from Spanish institutions and 35% from other countries.

Parc Recerca Universitat Autònoma de Barcelona – IBB (MRB Building) Universitat Autònoma de Barcelona Bellaterra, Barcelona, 08193 SpainBiotech company dedicated to the discovery, development, and commercialization of innovative protein technologies for the pharmaceutical and biotech markets. Our two proprietary technologies, ZERA and SPLITTERA, are powerful tools for the production and processing of recombinant proteins and for the improvement of biotherapeutics' performance: protein engineering, antibody conjugation, gene therapy,… Both technologies are subjected to continuous upgrade cycles and constant search for novel applications in collaboration with academic and industrial partners.

Avda del Desarrollo Tecnológico, 11 Jerez de la Frontera, Cádiz, 11591 SpainBiotech company dedicated to the discovery, development, and commercialization of innovative protein technologies for the pharmaceutical and biotech markets. Our two proprietary technologies, ZERA and SPLITTERA, are powerful tools for the production and processing of recombinant proteins and for the improvement of biotherapeutics' performance: protein engineering, antibody conjugation, gene therapy,… Both technologies are subjected to continuous upgrade cycles and constant search for novel applications in collaboration with academic and industrial partners.

Vía Hispanidad, 21 (edificio Araclon) Zaragoza, Zaragoza, 50009 SpainAraclon Biotech is a small company founded in 2004 dedicated to the research and development of therapies and diagnostic methods for Alzheimer’s disease. Even though being a small company, Araclon is part of Grifols, being the major shareholder, so it has been classified as a large business. Currently we offer the quantification of Alzheimer's Disease relevant Aβ42 and Aβ40 peptides in plasma by two proprietary methods: ELISA and Liquid-Chromatography-Mass Spectrometry assays. These assays are carried out as a service at our facilities in Spain and US.

c/ Doctor Trueta 183 Barcelona, 08005 SpainDeveloping the Algorithms to Automate Drug Discovery Our mission is to accelerate the transition to rational, computerized drug discovery via simulations and machine learning. We developed the first online platform for drug design based on deep learning and are now leading the introduction of machine learning techniques into the drug discovery pipeline.

c/ Argenters 6 Pol. Ind. Santiga Santa Perpètua de Mogoda, Barcelona, 08130 SpainAnaPath Services is an independent, Swiss based contract laboratories focused on histopathology services. AnaPath Services was founded in 2012 and is GLP certified 2013. AnaPath Research S.A.U is an AnaPath Services subsidiary located in Barcelona for the conduct of in vivo saftey assesment studies. AnaPath is a team of scientists of different nationalities who are internationally recognized. AnaPath Services were founded to provide reliable, competent and timely services in toxicological and experimental pathology and anatomy. Furthermore, our work combines not only the core business of toxicological pathology but also neuropathology, inhalation pathology, bone marrow evaluations, immunological processes, pathology in unusual laboratory species (fish, amphibian, birds, and invertebrates), hard material techniques, immunohistochemistry, fetal pathology and image analysis. Pathologists, anatomists and other staff members offer their more than 500 years of combined experience from basic consulting via advising study designs and offers for education, to traditional histopathology as well as complex evaluations. In addition, AnaPath GmbH and AnaPath Services are working together with a worldwide network of partners.

Pol Mocholí, C. Noáin, 1 Noáin, Navarra, 31110 SpainArdena is your reliable partner to navigate your small molecule through drug development into the clinic. We make, analyse and file your investigational drug. We offer an integrated services platform to reduce the timeline from initial idea to first-in-human (FIH) clinical verification. We reduce the risk, time and cost to bring your drug to the clinics and market. Take advantage of phase appropriate development and dedicated project management. GMP manufacturing services for clinical trials Phase 1 and Phase 3 clinical trials Drug substance and drug product development ICH stability studies Clinical packaging / labeling / supply services Bio-analytical services

Barcelona, CT SpainBCN Peptides offers generic peptides, custom peptide synthesis, and HPLC purification.

Parque Tecnológico de Bizkaia/ Bizkaia Technology Park. Ibaizabal Bidea (Edificio 800 - 2) Zamudio, Biscay 48170 SpainBiofungitek offers mechanism of action studies, sporulation, in vitro high throughput screening assays, and fraction libraries for anti-fungal research.

C/ Centre Esther Koplowitz (CEK, Rosselló 153) 08036 BarcelonaThe biobank is a platform which works to obtain, store, manage and distribute large collections of human biological samples of phenotypes and diseases of marked interest for researchers. This makes work possible for many researchers, who may additionally request technical advice on human sample collection projects.

Calle Azcárraga 12A Oviedo, Asturias C.P 33010 SpainBAP Health Outcomes Research develops clinical studies and specializes in medical writing, pharmacoeconomics, data analysis, and statistical modeling.

Hospital Duran i Reynals 3a planta - Gran Via de l'Hospitalet, 199 Hospitalet de Llobregat, Barcelona, 08908 SpainResearch centre for cancer, neurosciences and translational medicine The Bellvitge Biomedical Research Institute (IDIBELL) is a biomedical research center established in 2004. Its stakeholders are Bellvitge University Hospital and Viladecans Hospital of the Catalan Institute of Health, the Catalan Institute of Oncology, University of Barcelona and the town council of L’Hospitalet de Llobregat. IDIBELL is located in L’Hospitalet de Llobregat, south of Barcelona. It is a member of the Campus of International Excellence of the University of Barcelona HUBc and part of the CERCA institution of the Generalitat of Catalonia. In 2009, it became one of the first five Spanish research centers accredited as a health research institute by the Carlos III Institute of Health. A key aspect of research in IDIBELL is its proximity to the patient. Because of its location and the healthcare activity that many of its researchers carry out, IDIBELL research groups can identify which problems are really priority and which solutions are effective in daily clinical practice.

Hospital Duran i Reynals 3a planta - Gran Via de l'Hospitalet, 199 08908 Hospitalet de Llobregat Barcelona - SpainResearch centre for cancer, neurosciences and translational medicine The Bellvitge Biomedical Research Institute (IDIBELL) is a biomedical research center established in 2004. Its stakeholders are Bellvitge University Hospital and Viladecans Hospital of the Catalan Institute of Health, the Catalan Institute of Oncology, University of Barcelona and the town council of L’Hospitalet de Llobregat. IDIBELL is located in L’Hospitalet de Llobregat, south of Barcelona. It is a member of the Campus of International Excellence of the University of Barcelona HUBc and part of the CERCA institution of the Generalitat of Catalonia. In 2009, it became one of the first five Spanish research centers accredited as a health research institute by the Carlos III Institute of Health. A key aspect of research in IDIBELL is its proximity to the patient. Because of its location and the healthcare activity that many of its researchers carry out, IDIBELL research groups can identify which problems are really priority and which solutions are effective in daily clinical practice.

C / Capitan Aranda Baja 12 under. 23001 Jaén (Spain)Our company was established in 2012 and since then we have accumulated to the already comprehensive of its staff, which supports us as professionals plant health applied research and the study and interpretation of the natural environment experience. We conducted official tests and demos for a major multinational plant health, pear also small manufacturers and even professional groups. We have worked with application of chemical insecticides with release of predators of pests and treatments in biological control organisms and other means of phytosanitary defense. We have participated in research programs at the University of Cordoba. The company is also conducting studies of the natural environment in the archaeological site of Castulo (Jaen) cataloging the fauna, flora and vegetation of the site and its surroundings. They have launched initiatives to explain the natural environment of protected sites, are designed gardens and projects have been carried correction erosion.

C/ Henares, 16-18 Velilla de San Anton Madrid, 28891 SpainBeslan is a full service contract manufacturer of herbal, vitamin, mineral, and dietary supplements. Beslan SL offers a comprehensive package of nutritional and nutraceutical products and services.

Edificio 801. Parque Tecnológico de Vizcaya Derio Bilbao, Vizcaya 48160 SpainBRAINco Biopharma focuses on research in neurological diseases and psychiatric disorders and develops stable cell lines, optimized cell based assays for High Throughput Screening, lead molecules, and animal models.

Calle Calzada Romana 40 Camas, Sevilla, 41900 SpainBiomedal S.L. is a biotechnology company which develops and supplies analytical laboratory services and innovative products for the control of disease progressions. The company vision is to be an international reference in innovative products and services for the diagnosis and monitoring of celiac disease and other chronic immune diseases as well as supporting the food industry in the identification of allergens and contaminants.Biomedal Life Science also offers oligo synthesis, protein synthesis, antibody synthesis, gene cloning, expression and purification services.

Via Augusta 59 (office 707) Barcelona, Barcelona, 08006 SpainBioinfogate, a leading data science organization, is the producer of the OFF-X ™ portal. OFF-X is the first translational safety intelligence portal that allows drug R&D scientists to be promptly informed about the target modulating effects of small molecules and biologics leading to preclinical toxicity and clinical adverse events. Updated daily with expertly curated safety alerts, OFF-X covers more than 5,500 targets in all stages of drug R&D development from emerging and first-in-class targets to targets for drugs that have reached the marketplace. OFF-X aims to promptly identify toxicology & safety signals and de-risk R&D programs.

59 Via Augusta Barcelona, CT, 08006 SpainBioinfogate, a leading data science organization, is the producer of the OFF-X ™ portal. OFF-X is the first translational safety intelligence portal that allows drug R&D scientists to be promptly informed about the target modulating effects of small molecules and biologics leading to preclinical toxicity and clinical adverse events. Updated daily with expertly curated safety alerts, OFF-X covers more than 5,500 targets in all stages of drug R&D development from emerging and first-in-class targets to targets for drugs that have reached the marketplace. OFF-X aims to promptly identify toxicology & safety signals and de-risk R&D programs.

Comte de Salvatierra 5 (ento 1ª) Barcelona, Barcelona, 08006 SpainBioinfogate, a leading data science organization, is the producer of the OFF-X ™ portal. OFF-X is the first translational safety intelligence portal that allows drug R&D scientists to be promptly informed about the target modulating effects of small molecules and biologics leading to preclinical toxicity and clinical adverse events. Updated daily with expertly curated safety alerts, OFF-X covers more than 5,500 targets in all stages of drug R&D development from emerging and first-in-class targets to targets for drugs that have reached the marketplace. OFF-X aims to promptly identify toxicology & safety signals and de-risk R&D programs.

c/ Catedrático Agustín Escardino Benlloch, 9 Parc Cientific Universitat València, Ed. 2 Paterna, Valencia, 46980 SpainBiopolis offers services for the design, purification and production of microorganisms and cellular metabolites as well as next generation DNA sequencing.

nº 9 C/ Catedrático Agustín Escardino Parc Científic Universitat València, Ed. 2 Paterna, Valencia, Comunidad Valenciana, 46980 SpainBiopolis offers services for the design, purification and production of microorganisms and cellular metabolites as well as next generation DNA sequencing.

nº 9 C/ Catedrático Agustín Escardino Parc Científic Universitat València, Ed. 2 Paterna, Valencia, Comunidad Valenciana, 46980 SpainBiopolis offers services for the design, purification and production of microorganisms and cellular metabolites as well as next generation DNA sequencing.

Finca La Dehesilla Ctra. A-362, Km. 4.7 Utrera, Seville, 41710 SpainAs a reliable partner, we offer you comprehensive solutions with our services in the divisions of ecotoxicology, field testing and agricultural analytics in connection with the admission/registration of your products and active substances. Whatever you want to outsource in these areas – we can provide you the security you require – thanks to our twenty years of experience – so that your project feels to be in good hands. An active cooperation is the driving force behind our actions. Our range of services extends from the search for intelligent solutions to the use of specific test methods and most modern techniques to quality assurance and the desired cooperation with the competent authorities. You can rely on a precise result.

P. Mikeletegui 56 San Sebastian, 20009 SpainWe are the leading CRO in zebrafish studies thanks to our more than 18 years of experience with this alternative model. During those years we have developed several validated assays on the areas of disease model generation, efficacy and toxicity carried to Pharma, Biotech, Chemical, Cosmetic, Nutraceutical, and Tobacco companies. Apart from our Know-How another of our main values is Audacity because we are experts in listening to our customer's needs to develop tailor-made solutions based on their requirements. Also thanks to our automated and innovative tools, our validated assays are carried out with our High Content Screening (HCS) platform, allowing us to perform fast and cost-effective assays in zebrafish: - Target Validation with Morpholinos or CRISPR/Cas13 - Zebrafish Disease Models: genetic mutations, transgenesis, and chemically induced models. - Toxicity Assays: acute toxicity, neurotoxicity, developmental/teratogenic toxicity, cardiotoxicity, hepatotoxicity, ototoxicity, immunotoxicity, nephrotoxicity, behavior alteration assay. - Ecotoxicity Assays: Algal Microplate toxicity test, Daphnia magna immobilization assay, endocrine disruption assay in zebrafish, and zebrafish larvae acute toxicity assay. - Efficacy Assays: Oncology (angiogenesis inhibition assay, target validation, cancer models generation, xenograft zebrafish embryos), CNS (Neuroprotection, Epilepsy, Parkinson, Alzheimer...), rare diseases, metabolism, immune system, cardiovascular… - Cosmetics: regeneration, melanin quantification, and antioxidant assays.

Mikeletegi Pasealekua, 56 Donostia-San Sebastian Gipuzkoa, Donostia, 20009 SpainWe are the leading CRO in zebrafish studies thanks to our more than 18 years of experience with this alternative model. During those years we have developed several validated assays on the areas of disease model generation, efficacy and toxicity carried to Pharma, Biotech, Chemical, Cosmetic, Nutraceutical, and Tobacco companies. Apart from our Know-How another of our main values is Audacity because we are experts in listening to our customer's needs to develop tailor-made solutions based on their requirements. Also thanks to our automated and innovative tools, our validated assays are carried out with our High Content Screening (HCS) platform, allowing us to perform fast and cost-effective assays in zebrafish: - Target Validation with Morpholinos or CRISPR/Cas13 - Zebrafish Disease Models: genetic mutations, transgenesis, and chemically induced models. - Toxicity Assays: acute toxicity, neurotoxicity, developmental/teratogenic toxicity, cardiotoxicity, hepatotoxicity, ototoxicity, immunotoxicity, nephrotoxicity, behavior alteration assay. - Ecotoxicity Assays: Algal Microplate toxicity test, Daphnia magna immobilization assay, endocrine disruption assay in zebrafish, and zebrafish larvae acute toxicity assay. - Efficacy Assays: Oncology (angiogenesis inhibition assay, target validation, cancer models generation, xenograft zebrafish embryos), CNS (Neuroprotection, Epilepsy, Parkinson, Alzheimer...), rare diseases, metabolism, immune system, cardiovascular… - Cosmetics: regeneration, melanin quantification, and antioxidant assays.

Parque Tecnológico de León, Parcela M-10.4 24009 ARMUNIA León SpainBiomar Microbial Technologies is a Biotechnological company specializing in Marine Microbiology and the Chemistry of Natural Products, with the maximum technological capabilities to take advantage of the sea’s resources.

Parque Tecnológico de León, Parcela M-10.4 24009 ARMUNIA León. SpainBiomar Microbial Technologies is a Biotechnological company specializing in Marine Microbiology and the Chemistry of Natural Products, with the maximum technological capabilities to take advantage of the sea’s resources.

Pol Emiliano Revilla Ind. Sanz Avenue Agreda, thirty-six Ólvega, Soria 42110 SpainCyndea Pharma specializes in contract manufacturing and packaging of generic drug products.

C / Melchor Fernández Almagro, 3 Madrid, E-28029 SpainCentro Nacional de Investigaciones Oncologicas (CNIO) focuses on research in cancer and offers its facilities to provide cytogenetics, molecular diagnostics, histopathology, DNA sequencing, tumor banking, and DNA microarray services.

Berlin, 38-48 7ª planta 08029 Barcelona - SpainChiesi farmaceutici offers drug development, drug discovery, and clinical trials.

Vía de las dos Castillas, 33 Atica 7-Edificio 7 PLANTA 3 28224 Pozuelo de Alarcón (Madrid) SpainCasen Fleet provides pharmaceutical products, improvement of current products, market studies and analysis of projects.

Autovía Logroño,km. 13.300 50180 Utebo (Zaragoza) SpainCasen Fleet provides pharmaceutical products, improvement of current products, market studies and analysis of projects.

ICIQ - Av Paisos Catalans, 16 43007 Tarragona - SpainCSOL offers innovative, tailor-made catalyst solutions for homogeneous transformations, including enantioselective reactions.

El Puerto de Santa María, 11500 SpainCuraxys sprouted as an innovating idea from the founding member, who owns a deep market insight thanks to more than 35 years’ experience in the biopharmaceutical field.

Barcelona, CT, 08028 SpainChemotargets S.L. is a computationally-oriented biotech company focused on the drug discovery and development areas. Located in Barcelona, it was founded on March 2006 as a spin-off initiative from the Chemogenomics Laboratory under the auspices of the Municipal Institute of Medical Research (IMIM-Hospital del Mar). Chemotargets' goal is to help the biopharma industry fast-forward the process of bringing new medicines to market, speeding up drug discovery and development programs and making them more cost-efficient. To this end, Chemotargets has designed, and continues developing, an integrated technology platform involving a broad spectrum of cutting-edge computational methodologies. Since 2006, Chemotargets has provided computational drug discovery services to a great number pharmaceutical and biotech companies and carried out collaboration agreements with different academic and research institutions. In addition, Chemotargets is currently participating in three different EU funded research projects; eTOX, focused on the in silico prediction of in vivo toxicities associated with drugs and drug candidates, CHAARM, focused on the development of combinations of highly active specifically-targeted microbicides for vaginal and rectal application and MICROSMETICS, focused on the discovery and development of novel cosmeceutical agents.

Madrid, SpainCentro Nacional de Invest. Cardio. provides cytometry, proteomics, transgenesis, viral vectors, microscopy, and gene targeting.

C/ Melchor Fernández Almagro 3 Madrid, Madrid, 28029 SpainThe National Cancer Research Centre (CNIO) was created in 1998 by the Institute of Health Carlos III, although it was founded by the Ministry of Health, the CNIO is integrated since the end of 2011 in the Ministry of Economy and Competitiveness . The CNIO is managed by a foundation, created simultaneously with the Center, whose name is that of the Carlos III National Center for Cancer Research Foundation. The Foundation has the status of state - owned foundation and is governed by a Board . Center corresponds develop scientific activity and is headed by a Director and assisted by a Scientific Advisory Committee The essential mission of the CNIO is to carry out research of excellence and to offer innovative technology in the field of cancer to the National Health System and to the National System of Science and Innovation. For this purpose, the strategic objectives of the CNIO are: To carry out an investigation to obtain new and more effective methods of diagnosis and treatment of oncological diseases. To transfer the scientific knowledge to the clinical practice, obtaining that the scientific advances repercuss as soon as possible on our sanitary system and, therefore, on the well-being of the patients. Transfer the technology developed in the CNIO to innovative companies. Establish a new and more effective management system in the European scientific field. The CNIO is one of the few European cancer centers that destines its resources to basic and applied research under an integrated approach, favoring the interaction of basic research programs with those of molecular diagnosis and discovery of new drugs, all supported by a Solid equipment infrastructure and technical services. The management system of the CNIO combines business flexibility, which derives from its founding nature, with the accounting rigor derived from its status as a state-owned foundation and from the control and justification of the public funds received.

C/ Dr. Aiguader, 88 Barcelona, 08003 SpainCentre for Genomic Regulation (CRG) focuses on research and offers in house facilities for protein expression and histology services.

Plaza de Ramón y Cajal Madrid, Comunidad de Madrid, 28040 Spain

Barcelona, CT SpainCERETOX offers experimental toxicology, nanotoxicology and ecotoxicology services to the public and private sectors.

Parc Científic de Barcelona Campus Diagonal-Universitat de Barcelona Edifici Clúster C/ Baldiri Reixac, 10 Barcelona, 08028 SpainCERETOX offers experimental toxicology, nanotoxicology and ecotoxicology services to the public and private sectors.

PARQUE TECNOLOGICO DERIO EDIFICIO 802 DERIO, BASQUE COUNTRY, 48160 SpainCocoon Bioscience is a biotechnology company dedicated to the production of recombinant proteins. Cocoon leverages a novel, automated expression system in which insects in their chrysalis stage serve as natural bioreactors. Our unique technology allows us to produce enzymes involved in modifying nucleic acids – like phi polymerase, T4 DNA Ligase, Pyrophosphatase, and other enzymes in the mRNA and plasmid DNA workflow as well as growth factors for the cultivated meat market. We work in tailor made projects for expression of difficult to express proteins.

Avd. Sudáfrica 110, 11408, Jerez de la Frontera, Cádiz (España)Cosmeservice is a global company specializing in cosmetic safety and regulation. We offer support and advice to cosmetic companies worldwide which plan to market their products in the European Union. Based on a customer-oriented philosophy, Cosmeservice strives to adapt to each new product and offer a comprehensive service. Cosmeservice arose from the experience of highly qualified professionals in Cosmetic Safety and Regulation. We offer comprehensive advice/service to cosmetic manufacturers and distributors in compliance with the regulatory requirements of the European Regulation. The purpose of Cosmeservice is to actively contribute to the consolidation of manufacturers and distributors in the European cosmetic market. We operate with the highest quality, reliability, and safety for the consumers.

Ildefonso Carrascosa 6 Poligono Industrial Mediterráneo Massalfassar, València, 46560 SpainCosmeservice is a global company specializing in cosmetic safety and regulation. We offer support and advice to cosmetic companies worldwide which plan to market their products in the European Union. Based on a customer-oriented philosophy, Cosmeservice strives to adapt to each new product and offer a comprehensive service. Cosmeservice arose from the experience of highly qualified professionals in Cosmetic Safety and Regulation. We offer comprehensive advice/service to cosmetic manufacturers and distributors in compliance with the regulatory requirements of the European Regulation. The purpose of Cosmeservice is to actively contribute to the consolidation of manufacturers and distributors in the European cosmetic market. We operate with the highest quality, reliability, and safety for the consumers.

Seville, AL SpainChemNature provides natural product chemistry and custom synthesis, and Best Service Ever . **Test Company for Demos**

3772 Semania Circle Seville, 7202 SpainChemNature provides natural product chemistry and custom synthesis, and Best Service Ever . **Test Company for Demos**

2 Calle Quintanavides Edificio Gorbea lll Madrid, Comunidad de Madrid, 28050 SpainCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

Avda Menendez Pidal s/n Grupo GC05 Córdoba, Córdoba, 14004 SpainCOBIOMIC is a spin-off of the University and the Biomedical Institute of Cordoba, Spain. The Commercial pipeline of the company is providing Proteomics Analysis services by qPCR using a novel technology (Proximity Extention Assay). 1ul of any biological sample (Serum, Dried Blood Spot, CSF, Tissue Lysate, Teardrops, etc..) can be used to determine the expression levels of 100s of proteins. Bioinformatics analysis can also be provided as an add-on, post analysis. The R&D pipeline of the company is focused on Biomarker Discovery, with the goal to develop a platform/prodcut, that would identify responders vs non-reponders of Biologics in patients suffering from Autoimmune conditions.

Don Pedro 7 - 3D Madrid, Madrid, 28005 SpainThe Spanish Pharmacoepidemiological Research Center (CEIFE) was created in 1994 as a research center in Madrid. Its aim is the realization of high - quality epidemiological studies on safety and effectiveness of drugs, using automated databases. The main sources of information are four medical databases: Clinical Practice Research Datalink and The Health Improvement Network, both in Britain BIFAP database and database Saskatchewan in Canada.

Calle Almte., 28 Calle Almte., 28, 28004 Madrid, EspañaThe Spanish Pharmacoepidemiological Research Center (CEIFE) was created in 1994 as a research center in Madrid. Its aim is the realization of high - quality epidemiological studies on safety and effectiveness of drugs, using automated databases. The main sources of information are four medical databases: Clinical Practice Research Datalink and The Health Improvement Network, both in Britain BIFAP database and database Saskatchewan in Canada.

Calle Astronoma Cecilia Payne, s/n, Ed. Canvax Parque Científico y Tecnológico Rabanales 21, Córdoba, 14014 SpainAbout Canvax™ Since 2001, Canvax has been an original Manufacturer & Supplier of the Most Innovative Enzymes, Kits, Buffers and Reagents. Due our customizable and adaptable manufacturing structure, reduced overhead and capacity to BULK manufacturing with the highest quality standards, we are leading the Life Science industry in terms of product performance, manufacturing capabilities and customer-service. Advantages & Features >> Highly Specialized & Largest Range: 300+ different Life Sciences Services availables. >> Latest Equipment & Technologies: made in Canvax™ Headquarters, 2 Full-equipped Manufacturing sites in Valladolid, Spain, with a total area of 3,400 m². >> Experienced Staff: Canvax™ PhD Team has an average 20+ years’ experience hands-on. >> Cost-Advantage: due the use of Highly Innovative & Premium Quality Products, manufactured by Canvax™. >> Trustworthy: Confidentiality Agreement, Technical Advice, regular updates, Go-No Go steps, and much more. >> Custom-tailored & Modularized Services: to assure that every step meets your needs. >> Bilingual Technical Support: for easier understanding, your inquiries would be answered in Spanish or English. Canvax™ have complete with great Results really different types of R&D Services, to Big Pharmaceuticals Companies, CROs, Industry, or Academia Research Centers worldwide. Below there is a list of some examples of the Services that we provided in the past. Please, contact your Exclusive Distributor to get a fast and no-obligation Quotation, even when your Project is not included in the listing or looks related.

Parque Científico y Tecnológico Rabanales 21, c/Astrónoma Cecilia Payne s/n, Edificio Canvax, ​14014 Córdoba (Spain)About Canvax™ Since 2001, Canvax has been an original Manufacturer & Supplier of the Most Innovative Enzymes, Kits, Buffers and Reagents. Due our customizable and adaptable manufacturing structure, reduced overhead and capacity to BULK manufacturing with the highest quality standards, we are leading the Life Science industry in terms of product performance, manufacturing capabilities and customer-service. Advantages & Features >> Highly Specialized & Largest Range: 300+ different Life Sciences Services availables. >> Latest Equipment & Technologies: made in Canvax™ Headquarters, 2 Full-equipped Manufacturing sites in Valladolid, Spain, with a total area of 3,400 m². >> Experienced Staff: Canvax™ PhD Team has an average 20+ years’ experience hands-on. >> Cost-Advantage: due the use of Highly Innovative & Premium Quality Products, manufactured by Canvax™. >> Trustworthy: Confidentiality Agreement, Technical Advice, regular updates, Go-No Go steps, and much more. >> Custom-tailored & Modularized Services: to assure that every step meets your needs. >> Bilingual Technical Support: for easier understanding, your inquiries would be answered in Spanish or English. Canvax™ have complete with great Results really different types of R&D Services, to Big Pharmaceuticals Companies, CROs, Industry, or Academia Research Centers worldwide. Below there is a list of some examples of the Services that we provided in the past. Please, contact your Exclusive Distributor to get a fast and no-obligation Quotation, even when your Project is not included in the listing or looks related.

C/ Luis de Mercado, 19 Parque Tecnológico de Boecillo Boecillo, Valladolid, 47151 SpainAbout Canvax™ Since 2001, Canvax has been an original Manufacturer & Supplier of the Most Innovative Enzymes, Kits, Buffers and Reagents. Due our customizable and adaptable manufacturing structure, reduced overhead and capacity to BULK manufacturing with the highest quality standards, we are leading the Life Science industry in terms of product performance, manufacturing capabilities and customer-service. Advantages & Features >> Highly Specialized & Largest Range: 300+ different Life Sciences Services availables. >> Latest Equipment & Technologies: made in Canvax™ Headquarters, 2 Full-equipped Manufacturing sites in Valladolid, Spain, with a total area of 3,400 m². >> Experienced Staff: Canvax™ PhD Team has an average 20+ years’ experience hands-on. >> Cost-Advantage: due the use of Highly Innovative & Premium Quality Products, manufactured by Canvax™. >> Trustworthy: Confidentiality Agreement, Technical Advice, regular updates, Go-No Go steps, and much more. >> Custom-tailored & Modularized Services: to assure that every step meets your needs. >> Bilingual Technical Support: for easier understanding, your inquiries would be answered in Spanish or English. Canvax™ have complete with great Results really different types of R&D Services, to Big Pharmaceuticals Companies, CROs, Industry, or Academia Research Centers worldwide. Below there is a list of some examples of the Services that we provided in the past. Please, contact your Exclusive Distributor to get a fast and no-obligation Quotation, even when your Project is not included in the listing or looks related.

C/ Luis de Mercado, 19 Parque Tecnológico de Boecillo Boecillo, Valladolid, 47151 SpainAbout Canvax™ Since 2001, Canvax has been an original Manufacturer & Supplier of the Most Innovative Enzymes, Kits, Buffers and Reagents. Due our customizable and adaptable manufacturing structure, reduced overhead and capacity to BULK manufacturing with the highest quality standards, we are leading the Life Science industry in terms of product performance, manufacturing capabilities and customer-service. Advantages & Features >> Highly Specialized & Largest Range: 300+ different Life Sciences Services availables. >> Latest Equipment & Technologies: made in Canvax™ Headquarters, 2 Full-equipped Manufacturing sites in Valladolid, Spain, with a total area of 3,400 m². >> Experienced Staff: Canvax™ PhD Team has an average 20+ years’ experience hands-on. >> Cost-Advantage: due the use of Highly Innovative & Premium Quality Products, manufactured by Canvax™. >> Trustworthy: Confidentiality Agreement, Technical Advice, regular updates, Go-No Go steps, and much more. >> Custom-tailored & Modularized Services: to assure that every step meets your needs. >> Bilingual Technical Support: for easier understanding, your inquiries would be answered in Spanish or English. Canvax™ have complete with great Results really different types of R&D Services, to Big Pharmaceuticals Companies, CROs, Industry, or Academia Research Centers worldwide. Below there is a list of some examples of the Services that we provided in the past. Please, contact your Exclusive Distributor to get a fast and no-obligation Quotation, even when your Project is not included in the listing or looks related.

Parc Científic de la Universitat de Barcelona. C/ Baldiri Reixac, 10 - 12. Barcelona. 08028 - SpainCIRCE is a company focused on crystal engineering and computational chemistry, which provides global solutions to pharmaceutical companies concerning solid state problems, maximizing the value of their active pharmaceutical ingredients (API). We accomplish this through a combined virtual/experimental holistic approach of polymorph, salt and cocrystal screenings, based on the use of the most advanced technologies and facilities together with exclusive and innovative computational prediction methodologies. CIRCE’s predictive techniques highly reduce the large number of experimental tests needed in the long and expensive conventional screening methods, typically based on chemical intuition, and minimize the effects of serendipity. Furthermore it extraordinarily increases the possibilities of achieving new crystalline forms.

Av. Benjamin Franklin 19 Paterna, Valencia, 46980 SpainCurapath is a leading polymer and lipid manufacturing company offering end-to-end solutions for therapeutic development, specializing in CDMO services. Our state-of-the-art facilities enable GMP manufacturing of polymer and lipid-based therapeutics, providing proven scale-up capabilities, analytic development, and a comprehensive CMC package, including: - Preclinical Development - Technology Transfer - GMP Manufacturing - Drug Product Formulation, Fill & Finish services to support clinical development - Method Development, Validation and ICH - Stability studies - CMC Regulatory support for IND & BLA submission For drug substance (DS) manufacturing, we specialize in kg-scale GMP production of polymers and lipid excipients, including polymer-conjugate DS with a scalable option of up to 6 kg per batch for commercial stage supply. Regarding formulation capabilities, our lipid nanoparticle (LNP) and polymer nanoparticle (PNP) services are optimized for screening and production of RNA and DNA delivery solutions. We offer support from development to commercialization, and our NanoScaler Knauer equipment is utilized for formulation and scale-up development, ranging from mL to L scale. This technology, proven in the formulation of LNPs for large-scale manufacturing of SARS-CoV-2 vaccines by BioNTech/Pfizer, allows us to transition seamlessly from R&D batches to GMP mRNA-LNP batches while maintaining rigorous standards. Finally, we have CDMO capabilities for formulating and scaling up development, especially considering our Fill & Finish services, which are well-suited for small to medium programs like Gene and Cell Therapies and Orphan Drug trials. 

C/Baldiri Reixac 4-8, torre I Parc Científic de Barcelona Barcelona, Barcelona, 08028 SpainBeCytes Biotechnologies is a biotechnological company that offers products and services (CRO) based on tissue procurement, cell isolation, and cell solutions for in vitro models addressed to the research community worldwide. The company’s main focus is the isolation and full characterization of primary human and animal hepatic and skin cells, as well as providing different tissue explants (pathological and healthy donors), together with CRO services related to our cells and tissues. BeCytes Biotechnologies offers an extensive portfolio of *fresh and cryopreserved human and animal cells*. Among others, plateable and suspension *hepatocytes, stellates, Kupffers, hepatic endothelial, liver sinusoidal endothelial cells, liver subcellular fractions, skin fibroblasts, and keratinocytes*. Some of BeCytes competitive advantages are: • Access to unlimited healthy and pathological human tissue • High expertise in cell isolation and cryopreservation with proprietary protocols • End-to-end control of the whole isolation process, from organ procurement to cell distribution • Production of Human hepatocytes and NPCs from the same donor • Extensive donor medical information • Adapted Liver Cells Conditions and CRO services • Logistic expertise to distribute fresh and cryopreserved cells • Laboratory with GMP conditions under requirement

Av. San Juan Bosco 13 Edificio CIBA, Planta A Zaragoza, Zaragoza, 50009 SpainBeCytes Biotechnologies is a biotechnological company that offers products and services (CRO) based on tissue procurement, cell isolation, and cell solutions for in vitro models addressed to the research community worldwide. The company’s main focus is the isolation and full characterization of primary human and animal hepatic and skin cells, as well as providing different tissue explants (pathological and healthy donors), together with CRO services related to our cells and tissues. BeCytes Biotechnologies offers an extensive portfolio of *fresh and cryopreserved human and animal cells*. Among others, plateable and suspension *hepatocytes, stellates, Kupffers, hepatic endothelial, liver sinusoidal endothelial cells, liver subcellular fractions, skin fibroblasts, and keratinocytes*. Some of BeCytes competitive advantages are: • Access to unlimited healthy and pathological human tissue • High expertise in cell isolation and cryopreservation with proprietary protocols • End-to-end control of the whole isolation process, from organ procurement to cell distribution • Production of Human hepatocytes and NPCs from the same donor • Extensive donor medical information • Adapted Liver Cells Conditions and CRO services • Logistic expertise to distribute fresh and cryopreserved cells • Laboratory with GMP conditions under requirement

Avda Mestre Mateo 2 Santiago de Compostela, A Coruña, 15706 SpainCeltarys Research is a start-up specialized in designing and synthesizing fluorescent probes to be used in the drug discovery process. We are experts in Chemical Biology and Medicinal Chemistry, with +20 years experience in research. We count with our own proprietary technology to develop fluorescent ligands with optimal pharmacological and photophysical properties. We have a validated portfolio of fluorescent GPCR ligands for Adenosine, Dopamine, Serotonin and Cannabinoids receptors. Moreover, our technology allows us to develop in a timely manner customized fluorescent ligands for any target with therapeutic interest.

C/ Hermanos del Moral 13 (Bajo E Madrid, 28019 SpainCliniSciences is a French company headquartered in Paris. CliniSciences is a distributor products & services from suppliers based all around the world. CliniSciences owns 10 other companies (Anawa, Biotrend, Generon, Hexabiogen, Kyvobio, Quimigen) based throughout Europe including the United Kingdom, Germany, Spain, Italy, The Netherlands & Switzerland. Through these companies we offer life science reagents, services and instruments. We sell products & services for research and diagnostic use. Products include reagents, cells, human samples and more. Services include antibody development, peptide synthesis, bulk manufacture, humanization and more.

Parque Tecnológico de Gipuzkoa. Paseo Miramón 182, Donostia / San Sebastián, , Gipuzkoa, 20009 SpainThe Center for Cooperative Research in Biomaterials- CIC biomaGUNE, located in San Sebastián (Spain), was officially opened in December 2006. CIC biomaGUNE is a non-profit research organization created to promote scientific research and technological innovation at the highest levels in the Basque Country following the BioBasque policy, in order to create a new business sector based on biosciences. Established by the Government of the Basque Country, CIC biomaGUNE constitutes one of the Centers of the CIC network, the largest Basque Country research network on specific strategic areas, having the mission to contribute to the economical and social development of the country through the generation of knowledge and speeding up the process that leads to technological innovation.

Parque Tecnológico de Gipuzkoa. Paseo Miramón 182, 20009 Donostia / San Sebastián, Gipuzkoa. Spain.The Center for Cooperative Research in Biomaterials- CIC biomaGUNE, located in San Sebastián (Spain), was officially opened in December 2006. CIC biomaGUNE is a non-profit research organization created to promote scientific research and technological innovation at the highest levels in the Basque Country following the BioBasque policy, in order to create a new business sector based on biosciences. Established by the Government of the Basque Country, CIC biomaGUNE constitutes one of the Centers of the CIC network, the largest Basque Country research network on specific strategic areas, having the mission to contribute to the economical and social development of the country through the generation of knowledge and speeding up the process that leads to technological innovation.

Parque Tecnologico de Bizkaia Edificio 801A Derio, Bizkaia, 48160 SpainCIC bioGUNE provides metabolics, phosphoromics, electron microscopy, crystallography, genomics, and proteomics services. Animal Facility AAALAC certified provide service for a large range of in vivo (mice) experimentation

PARQUE TECNOLOGICO DE BIZKAIA, 800 Derio, Bizkaia, 48160 SpainCIC bioGUNE provides metabolics, phosphoromics, electron microscopy, crystallography, genomics, and proteomics services. Animal Facility AAALAC certified provide service for a large range of in vivo (mice) experimentation

Correr de Rosa Luxemburg 9 Viladecans, Barcelona, 08840 SpainFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Sant Lluís 127 (corner La Plana 4) · E-25600 BALAGUER, Lleida · SpainDEVREG offers a confidential service external of consultancy focused on developing procedures and registration of chemicals in different countries, both in Europe and in other areas and countries of interest, following the national and zonal specific requirements. DEVREG aims to facilitate the achievement of clients, providing solutions to problems or concerns that arise during the process of obtaining approvals of their chemical products, including regular communication with the authorities involved in the evaluation. DEVREG work is supported by a professional team with extensive experience and knowledge in the compilation, preparation and registration of agrochemicals, fertilizers, biopesticides, biocides and livestock use products. A professional team, continuously trained and updated in terms of legal and procedural requirements, consists of 10 persons, includins regulatory scientifics, agronomist and documentation assistants who will work to provide a full service development, regulation and evaluation of their products.

Av Corts Catalanes, 9-11 (08173) Sant Cugat del Vallés, Barcelona SpainDextra international is a leading consultancy and representation firm providing innovative and valuable solutions to organizations facing the challenge of international growth.

Avenida de la Innovación 1 Edificio BIC Granada, Granada, 18016 SpainDESTINA is a diagnostics company, offering innovative Nucleic Acid Testing and molecular diagnostics assays solutions, with a particular emphasis on RNA detection and quantification. Our staff can upgrade your actual miRNA profiling into reliable, direct and absolute quantification of your target miRNA using DESTINA's ChemiRNA™ Tech. Challenging samples like serum, plasma, saliva and urine can all be handled using ChemiRNA™ Tech. Our technology can also be used for other types of RNAs such as mRNA, lncRNA, rRNA, circRNA. Furthermore, over the years, our team has developed an extensive experience in PNA chemistry. We are capable to design, synthesize and supply PNAs following strict quality control protocols to meet customer needs.

Calle Pallars 179-185, Barcelona 08005 (Spain)Draconis Pharma offers services in medicinal chemistry, analytical chemistry, primary/secondary screening, in-vitro and in-vivo efficacy assays, ADME-PK, toxicity/safety, and integrated services to support drug discovery

Pallars 179-185 Barcelona, 08005 SpainDraconis Pharma offers services in medicinal chemistry, analytical chemistry, primary/secondary screening, in-vitro and in-vivo efficacy assays, ADME-PK, toxicity/safety, and integrated services to support drug discovery

C/ Miguel de Mañara 11 Bajo D España Sevilla, Sevilla, 41004 Spain

Calle Finlandia 2 1º Oviedo, Asturias, 33010 SpainDreamgenics is a biotech company that offers bioinformatics analysis services for genomic, transcriptomic NGS data using our Genome One software. Genome One (CE-IVD certified) is an advanced tool that allows the integration of all the bioinformatics solutions required for the study, including read alignment, variant calling and annotation. Our analyses identify high-quality genomic variants through high sensitivity and specificity standards, extracting important biological information and reducing validation costs. The services that we offer are the following: WGS, WES, Transcriptomics (RNA-Seq) and Single cell RNA-Seq. Additionally, we hand in the results using our web viewer Genome One Reports. Lastly, we are an ISO 9001:2015, UNE-EN ISO 13485:2018 and UNE-ISO/IEC 27001:2017 certified company which represents our commitment to provide our customers with products and services that meet the most demanding quality standards.

Carrer d´Estruc 9 Barcelona, Barcelona, 08002 SpainDigital Chameleon is an owner-managed strategy advisory for digital transformation in the healthcare and life science sector. We support our customers with an experienced and competent Quality & Compliance Team, consisting of various experts from Pharma, BioTech and Medtech (BioTechnologists, Pharmacists, Pharmacists, Medical Technologists, Information Technologists, UX / Usability & Requirement Engineers). We specialize in digitalization in healthcare and orchestrate customers in the introduction and improvement of quality management in an agile environment in an environment restricted by regulations. Areas of tension are: Lean quality management systems, agile computer software validation and qualification, software as a medical device, digital health apps and digital health platforms, as well as quality & audit readiness of ultra-modern bio-tech laboratories and production facilities. In our methodology, we apply deep knowledge and understanding of regulations, standards and best practices from Pharma, BioTech and MedTech (EU GMP, FDA, MDR), future-oriented methods from UX / Usability & Requirement Engineering and agile software development frameworks (Scrum, Kanban ) at. We can therefore offer our customers a quality management system specially tailored to their needs, which navigates them easily and efficiently through the regulatory maze.

Carrer d´Estruc 9 Barcelona, Barcelona, 08002 SwitzerlandDigital Chameleon is an owner-managed strategy advisory for digital transformation in the healthcare and life science sector. We support our customers with an experienced and competent Quality & Compliance Team, consisting of various experts from Pharma, BioTech and Medtech (BioTechnologists, Pharmacists, Pharmacists, Medical Technologists, Information Technologists, UX / Usability & Requirement Engineers). We specialize in digitalization in healthcare and orchestrate customers in the introduction and improvement of quality management in an agile environment in an environment restricted by regulations. Areas of tension are: Lean quality management systems, agile computer software validation and qualification, software as a medical device, digital health apps and digital health platforms, as well as quality & audit readiness of ultra-modern bio-tech laboratories and production facilities. In our methodology, we apply deep knowledge and understanding of regulations, standards and best practices from Pharma, BioTech and MedTech (EU GMP, FDA, MDR), future-oriented methods from UX / Usability & Requirement Engineering and agile software development frameworks (Scrum, Kanban ) at. We can therefore offer our customers a quality management system specially tailored to their needs, which navigates them easily and efficiently through the regulatory maze.

The Parc Científic de Barcelona Torre R - 01B10 C/Baldiri Reixac, 4-12 i 15, Barcelona, Spain, 08028 SpainDevsynthesis is a Discovery Chemistry CRO from India. We offer Complex chemistry molecules mostly - rare to make targets for NCE or innovation towards the Biotech and Pharmaceutical companies. We have immense experience in “Complex Heterocyclic, Organic, Aliphatic & Aromatic compounds”, and “Complex multi-step synthesis” which includes “focused Libraries”, “building blocks”, and advanced intermediates. We also have extremely good experience working on Dyes, Linkers for the ADCs, and Molecular Glues. We have about 70 fume hoods and 80+ chemists and we are adding 90+ hoods with 100+ chemists at our facility in India and have inaugurated new facilities in Barcelona and USA recently. Also, we have an in-house analytical lab (NMR, LCMS, HPLC, Pre-HPLC, GC with Headspace, Combi-Flash systems, etc.). We offer these targets under FTE and FFS business arrangements. No. of Reactions per day: About 4 reactions (80 reactions/month) per day including purification and workup. No. of Samples analyzed per day: More than 110 NMR, HPLC samples; More than 120 LC-MS samples Scientific Team Ratio: 1 Ph.D. – 4 MSc

Carrer Baldiri Reixac, 4-8 Tower I, Floor 8 Barcelona, Barcelona, 08028 SpainProspective collection of Human Biological Samples for research. We tailor every obtainment circuit based on the research requirements. We can assess all types of organ, tissue and/or cell requests and manage fresh (<24h) or processed sample shipments. We are located in a hotspot for the donation environment, being Barcelona one of the regions from Europe with the highest number of donations per year. The Research Development Department of DTI Foundation has more than 10 years of experience in creating *prospective circuits* for the obtention of human biospecimen samples tailored to the client needs and requirements, which encompasses strong collaborations with national and international hospital procurement centers, biobanks and laboratories by supporting the creation of circuits for obtaining, processing and sending high quality human biological samples to research groups, whether promoted by research centers, hospitals, health centers, universities or biotechnology or pharmaceutical companies. In particular, the R+D+i department has extensive experience in the creation of prospective circuits for obtaining, storing and sending fresh biological samples for research. In the different projects that we coordinate, our team is in permanent contact with the medical teams, registering 24/7 possible donation alerts and assisting in-situ to the surgical rooms where the sample collection processes is performed. Thus allow us to evaluate the samples together with the medical teams and ensure a great control of quality and traceability throughout all the process. What we Do : High-quality samples provider Research projects networking Cooperation with biological samples couriers International collaboration with hospitals and labs Collaboration agreements with biobanks for sample processing and storage under GLP Tailored to client's needs Custom services Experts in 12/24h shipping in controlled temperature in Europe Find more information and see what we do in our LinkedIn page: Research and Development Department - DTI Foundation

Parc Cientific de Barcelona, Torre I, pl 8 Baldiri Reixac 4-8 Barcelona, Barcelona, 08028 SpainProspective collection of Human Biological Samples for research. We tailor every obtainment circuit based on the research requirements. We can assess all types of organ, tissue and/or cell requests and manage fresh (<24h) or processed sample shipments. We are located in a hotspot for the donation environment, being Barcelona one of the regions from Europe with the highest number of donations per year. The Research Development Department of DTI Foundation has more than 10 years of experience in creating *prospective circuits* for the obtention of human biospecimen samples tailored to the client needs and requirements, which encompasses strong collaborations with national and international hospital procurement centers, biobanks and laboratories by supporting the creation of circuits for obtaining, processing and sending high quality human biological samples to research groups, whether promoted by research centers, hospitals, health centers, universities or biotechnology or pharmaceutical companies. In particular, the R+D+i department has extensive experience in the creation of prospective circuits for obtaining, storing and sending fresh biological samples for research. In the different projects that we coordinate, our team is in permanent contact with the medical teams, registering 24/7 possible donation alerts and assisting in-situ to the surgical rooms where the sample collection processes is performed. Thus allow us to evaluate the samples together with the medical teams and ensure a great control of quality and traceability throughout all the process. What we Do : High-quality samples provider Research projects networking Cooperation with biological samples couriers International collaboration with hospitals and labs Collaboration agreements with biobanks for sample processing and storage under GLP Tailored to client's needs Custom services Experts in 12/24h shipping in controlled temperature in Europe Find more information and see what we do in our LinkedIn page: Research and Development Department - DTI Foundation

Sardenya 350 E-08025 Barcelona SpainEfarmes is a generic-development pharmaceutical company that focuses on generic dossier development, licensing out and supply of finished dosage forms.

República de El Salvador 27, 3C Santiago de Compostela, A Coruña, 15701 SpainEMphasis is a small team of structural biologists who provides cryo-electron microscopy (cryo-EM) research services to pharmaceutical companies and academic laboratories. We are specialised in high resolution 3D structure determination of proteins and macromolecular complexes. Our services, range from EM sample preparation and data collection through data processing and model building. EMphasis also offers tailored EM services for specific customer needs. We combine our insights and skills to optimise customer performance and productivity.

C/ General Ibáñez de Íbero, 1 28003 Madrid SpainEurodiagnóstico specializes in the distribution of ELISA reagents and kits for animal and human research and also in developing and manufacturing research products for molecular and cell biologists.

Paseo de la Castellana 177, 7ºD 1 28046 Madrid, SpainEurotrials, Scientific Consultants, is a privately owned company founded in Lisbon in 1995 by members of academia, medical community and pharmaceutical industry. It specializes in clinical research and scientific consultancy in the area of health and currently operates in Europe and Latin America. Eurotrials’ close collaboration with medical and regulatory institutions is an essential success factor that has been recognized by its partners, i.e. the pharmaceutical and international biotechnology industry, regulatory agencies, universities and clinical research centres., CROs and agro-food industry. The company’s success stands on pillars that have marked its personality since it was founded: creativity in finding solutions, unique technology, multidisciplinary expertise, solid experience and quality. It is qualified to participate in all the steps of any clinical, translational or epidemiological research project, from the initial research question to the final output. Eurotrials has a team of over 120 young, motivated employees and counts on diversity and interdisciplinarity to meet its customers’ needs. The team includes physicians, biologists, pharmacists, biostatisticians, sociologists, nutritionists, chemists, engineers, psychologists and mathematicians, among others.

Parc Cientific de Barcelona-Josep Samitier 1-5, 08028 Barcelona SpainERA Biotech develops and implements cell-based biomanufacturing technologies.

Poligono Industrial OesteVillapharma is a 15 year old synthetic chemistry company based in Spain. We offer competitive FTE rates as well as FFS synthesis, compound management, screening libraries and custom library services. We are part of Eurofins Discovery and can also integrate our services with our other 600 scientists inside In vitro, in vivo, ADME, Safety and phenotypic assays. In addition, Villapharma offers custom synthesis supporting Hit Generation, Hit-to-Lead and Lead Optimisation programmes for clients.

Parque Tecnologico de Fuente Alamo, Carretera El Estrecho-Lobosillo, Km 2.5 Fuente Álamo Murcia, 30320 SpainVillapharma is a 15 year old synthetic chemistry company based in Spain. We offer competitive FTE rates as well as FFS synthesis, compound management, screening libraries and custom library services. We are part of Eurofins Discovery and can also integrate our services with our other 600 scientists inside In vitro, in vivo, ADME, Safety and phenotypic assays. In addition, Villapharma offers custom synthesis supporting Hit Generation, Hit-to-Lead and Lead Optimisation programmes for clients.

km 2.5 Carretera El Estrecho-Lobosillo Carretera El Estrecho-Lobosillo, Km. 2,5 Fuente Alamo, Región de Murcia, 30320 SpainVillapharma is a 15 year old synthetic chemistry company based in Spain. We offer competitive FTE rates as well as FFS synthesis, compound management, screening libraries and custom library services. We are part of Eurofins Discovery and can also integrate our services with our other 600 scientists inside In vitro, in vivo, ADME, Safety and phenotypic assays. In addition, Villapharma offers custom synthesis supporting Hit Generation, Hit-to-Lead and Lead Optimisation programmes for clients.

1 Postigo de Zarate Granada, AL, 18001 SpainEra7 Bioinformatics is a company that provides services of NGS illumina and PacBio sequencing and bioinformatics analysis focused on bacterial genomics, metagenomics and trancriptomics. We also provide Inmmunogenomics services sequencing and analyzing TCR and BCR repertoires.

C/Santaigo Grisolía, 2 28760 Tres Cantos, Madrid SpainEnzymlogic is a world leader in the kinetic profiling of compounds to facilitate drug discovery. As experts in the generation and interpretation of kinetic data, we pride ourselves on a proven track record of successful partnerships with worldwide organizations of all sizes, supporting them on a routine basis during the early phases of drug discovery. We focus on the Hit to Lead (H2L) and Lead Optimization (LO) stages of drug discovery where our optimized kinetic profiling assays identify compounds with therapeutic potential that merit further progression into clinical trials. Our expertise in protein science and high-throughput screening enables drug hunters to speed up discovery decision-making, choosing the most promising molecules and eliminating under-performers, through a deeper understanding of the kinetics of compound-target interactions. We use exquisitely tuned assays to deliver accurate, robust and reproducible kinetic data of the highest quality that enhances the identification of compounds with the greatest therapeutic potential. The insight we provide facilitates the screening of compounds to iterate medicinal chemistry, understand pharmacokinetics/pharmacodynamics (PK/PD) disconnects and build better models to define therapeutic windows.

Baldiri Reixac 10 Parc Cientific de Barcelona Barcelona, Catalonia, 08028 SpainEnantia provides chemical services in the fields of medicinal chemistry, process R&D, custom synthesis and crystal engineering. Enantia is a leader in cocrystallization technologies and chiral chemistry. Enantia develops chemical and solid state technologies for the fine chemicals and pharmaceutical sectors. The company can contribute all the way from initial research in medicinal chemistry or route scouting to any phase of process R&D. Enantia's unique approach allows for creative and innovative solutions which make possible the most challenging projects. Enantia’s Medicinal Chemistry team is composed of experienced medicinal and synthetic chemists used to dealing with challenging targets and projects, such as the ones involving asymmetric chemistry to render 3D-shaped small molecules or just to introduce a chiral centre that can be key to achieve target selectivity. We synthesize, collaborating in the design when needed, focused libraries of new compounds or interesting scaffolds to carry out programs of drug discovery, covering hit finding, hit to lead and lead optimization to preclinical candidate. We can also prepare cold labelled compounds, standards and metabolites needed during the preclinical phase of the drug development. In our chemical RD department, we develop new routes of synthesis to be scaled-up and optimize chemical steps of current synthetic routes following our client’s requirements (yield, cost, etc.). We can also do impurity profiling and carry-over of a specific route of synthesis, as well as prepare new impurities that arise during stability testing and formulation of a given API. We tackle almost any type of projects, and we are particularly comfortable working on chiral molecules, especially when they need to be prepared in an enantiomerically pure form or resolved from complex mixtures. In addition, we can custom synthesize almost any compound up to kilo-lab in house. In this sense, we count with a new kilo-lab facility with a 15L jacketed reactor plus ancillary equipment. Enantia performs solid form screenings to find the best solid form of a given molecule. We study the different salts, polymorphs and cocrystals (and also solvates and hydrates if it is needed) that a compound (or a combination of them) can have. Furthermore, we count with a spray dryer (Mini Spray Dryer B-290 de Büchi) which can work with aqueous solutions and organic solvents, to perform amorphous form development. The different solid forms of a compound can modify several physicochemical properties of a given compound (solubility, light and thermal stability, rheology, etc.) allowing for example to transform an oily or liquid compound into a solid or to increase its bioavailability. Furthermore, solid forms are a good tool to increase the IP protection of a given molecule. Besides their applications to improve the physicochemical properties of a given compound and increase its IP protection, we also use cocrystallization technology to generate easy, efficient and scalable processes to purify and resolve compounds from complex mixtures. This is specially interesting when facing a purification or resolution that is technically very difficult or has an important economic impact. We usually apply this technology to avoid the use more expensive and time-consuming techniques such as chromatography, usually needed when the compounds cannot be purified through standard crystallization or when salt formation is not an option or not rendering good results. Enantia counts with a Solid Form Analysis department that offers services analysing APIs and excipients alone or in drug products, especially when developing new formulations or when problems appear during manufacturing, such as differences in two batches regarding properties like solubility or stability. We offer X-Ray, electronic microscopy, atomic forces microscopy, DVS, DSC, PSD and TGA among others for a really detailed understanding of the solid-state during drug development and manufacturing. We can also detect and quantify crystalline infringing forms of an API in a given matrix. For this, we can either use our own X-Ray diffractometer or use Synchrotron radiation, especially when the % of the form to be detected is very low, therefore very high sensitivity is needed. In this sense, Synchrotron X-Ray radiation is much more sensitive than a high resolution diffractometer, and recommended when the manufacturer needs to be sure of the absence of a given crystalline form.

C/GRECIA 80-4 MADRID, MADRID, 28341 SpainEvoEnzyme designs engineered enzymes for the pharmaceutical, chemical and environmental industries through directed evolution. The company specializes in customized biocatalysis projects.

Parque Científico de Madrid C/ Faraday 7 Madrid, Madrid, 28049 SpainEvoEnzyme designs engineered enzymes for the pharmaceutical, chemical and environmental industries through directed evolution. The company specializes in customized biocatalysis projects.

Parque Científico de Madrid C/ Faraday 7 Madrid, Madrid, 28049 SpainEvoEnzyme designs engineered enzymes for the pharmaceutical, chemical and environmental industries through directed evolution. The company specializes in customized biocatalysis projects.

Rossello 36, Cuarto, Primera Barcelona, 08029 SpainVirtual Human (digital) Twin technology. We leverage supercomputers to bring to the biomedical industry the most powerful medical testing platform for heart therapeutics. From patient MRIs. we build 3D digital hearts that beat in the machine and, from them, diverse virtual populations that include gender, geography and pathologies present in society. Modelling cell, tissue and full organ behaviour treated and untreated, our tool predicts efficacy and safety of cardiac device and drugs in patients. Our vision is massive testing to make clinical trials working for everyone, to de-risk and accelerate new treatments to market bringing sales forward and reaching out to more patients faster. ELEM is a spinoff from the Barcelona Supercomputer Centre.

Ctra. Colmenar Viejo km 9,100 Madrid, Madrid, 28034 Spain

C/BALDIRI REIXAC, 4-8 TD BARCELONA, BARCELONA, 0 Spain

Barcelona, SpainFenome Biotech offers imaging, molecular studies, genetically modified mouse models, behavioral studies, and CNS phenotyping services.

Pol. Ind. Argentum Platino s/n Rd, Delios’ Office Block 1st floor, n 22 CP. 41909 Salteras Sevilla, SpainEstablished in Seville, in 2014, Field Trials Services (FTS AgroConsulting) has been set up to offer a service line of high-quality on biological and environmental data. FTS AgroConsulting is committed to reach all targets of ready final reports. The information process between FTS AgroConsulting and our customers is to be of the best quality and reability, meeting their requirements during the whole study from beginning to end. That way our sponsors will achieve their objetives and a complete satisfaction. FTS AGROCONSULTING PEOPLE Our people love what they do. That’s what makes our philosophy great. Our works are always responsible and take ownership of our actions. Manuel Vargas, (1974), since 1998 has been closely linked to agrochemicals Research and Development, something which has enabled him to gain extensive valuable experience in this sector. Due to ongoing changes in the industry, he has kept updated non stop to expand his knowledge as far as the new lines of biological products are concerned. People who know Manolo occupationally claim that he is passionate and knowledgeable about the subject. – Manolo what would you do if you didn’t work in FTS Agroconsulting? I’d just create another company like it. Jose Manuel Peña, (1975), has been working on this sector for more than 12 years. He has gathered a wide experience on microorganism biocontrol as he was principal R&D investigator on registration of Trichoderma harzianum, Trichoderma viride and Beauveria bassiana. He has massive experience on bioagents. People who know Peña occupationally claim that he is a methodical person and a great observer. – Peña what would you do if you didn’t work in FTS Agroconsulting? I’d like to work in this sector abroad .

Av. del Cadí, 19-23 P.l. Sant Pere Molanta 08799 Olèrdola, Barcelona EspañaAgro-biotechnology company dedicated to the research, development, production and global commercialization of environment friendly products for the protection and nutrition of agriculture. The company manufactures and commercializes products to protect and improve the health and productivity of agriculture while minimizing the environmental impact, preserving the good health and balance of the crops and their surrounding environment.

Carretera de Irún Km. 26,2000. 28700 San Sebastián de los Reyes Madrid SpainFarmasierra offers services to mangage, distribute, promote, develop and optimize the production of medicinal products.

Madrid, Community of Madrid SpainFarmasierra offers services to mangage, distribute, promote, develop and optimize the production of medicinal products.

Avda Reyes Católicos, 2 Madrid, 28040 SpainFundacion Jimenez Diaz focuses on research in therapeutic areas of cancer, cardiovascular disease, infectious disease, inflammatory disease, and metabolic diseases.

Madrid, Community of Madrid SpainFundacion Jimenez Diaz focuses on research in therapeutic areas of cancer, cardiovascular disease, infectious disease, inflammatory disease, and metabolic diseases.

FITOSOIL - Pol. Industrial Oeste. Street/ Alcalde Clemente García plot 24/37, Module D1 y D2 - Post office box 200 - 30169 San GinésWe are a team of professionals and specialists with a very clear objective, to make available to our customers the latest technology to address the stringent legislative controls, as well as research and development of new analytical techniques for detection and quantification of chemical agents and biological. Our philosophy is based on three pillars: COMMITMENT - Quality - Speed - Impartiality - Confidentiality SERVICE - Management of the sampling - Preliminary results (fax, internet, @, etc.) - Graphical Reports - Interpretation of results - Consultation and advice HIGH TECHNOLOGY - Implementation of the latest analytical techniques - Commissioning of new methods - Standardized Tests

Dirección: Pompeu Fabra,8 25337 BELLCAIRE D’URGELL (Lleida)

Avenida Conocimiento 34 Armilla, Granada, 18016 SpainMEDINA is a non profit research organization providing a broad porfolio of drug discovery services to large and medium pharma, biotech and academics worldwide. MEDINA has multidisciplinary technology platforms involving high throughput screening, natural product chemistry, analytical tools and bioanalysis, metabolomics, industrial and molecular microbiology, fermentation, and preclinical in vitro ADME tox. MEDINA owns the largest Collections of Microbial Strains (190.000 strains) and a very diverse Natural Products Libraries (200.000 extracts). Our team has unique expertise in several disciplines such as: + Chemistry: isolation, analysis, dereplication and/or structural elucidation of Natural products. + Microbiology: Fermentation scale up and process improvement, microbial identification and diagnosis, search and selection of microorganisms with specific properties or chemistry, genome mining, strain engineering and heterologous expression. + High throughput screening (HTS): wide-range of cellular or target based bioassays, designed to discover new active principles with almost any type of assay format and readout. It could be applied on MEDINA´s natural product library, any commercial compound libraries or proprietary libraries of our partners. + Bioanalytics and Metabolomics: a. Early toxicological and pharmacological studies of new drugs and measurement of trace amounts of drugs and Natural Products in biological samples. b. Targeted and untargeted metabolomics in different human samples (e.g. for biomarker discovery) + ADME and Preclinical safety: wide range of in vitro ADME-Tox assays, and in vitro/in vivo Safety/Efficacy studies.

Urb. Monteprincipe/Facultad de Farmacia/USPCEU Boadilla del Monte, N/A, 28668 SpainCompany: Fundación Universitaria San Pablo CEU. Research centre: CEMBIO, Centre for Metabolomics and Bioanalysis. Faculty of Pharmacy. Madrid, Spain

Avinguda Països Catalans 16 Tarragona, Tarragona, 43007 SpainFounded in 2000 by the Government of Catalonia, the Institute of Chemical Research of Catalonia started its research activities in 2004. ICIQ is committed to performing excellent research at the frontier of knowledge in two main areas: Catalysis, Med Chem, Materials and Renewable Energy. The institute also has two other commitments: knowledge and technology transfer to the chemical, pharmaceutical and energy industrial sectors and that of training the future generation of scientists by offering high-quality educational programmes to master and PhD students as well as postdoctoral researchers. Our mission is to lead, from the vantage point of molecular science, cross-strategies for solving major social and economic challenges, such as climate change and sustainable supply of energetic and raw materials, thereby contributing to the establishment of a knowledge-based economy and improving quality of life for all. Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates.

Avinguda Països Catalans 16 Tarragona, Tarragona, 43007 SpainFounded in 2000 by the Government of Catalonia, the Institute of Chemical Research of Catalonia started its research activities in 2004. ICIQ is committed to performing excellent research at the frontier of knowledge in two main areas: Catalysis, Med Chem, Materials and Renewable Energy. The institute also has two other commitments: knowledge and technology transfer to the chemical, pharmaceutical and energy industrial sectors and that of training the future generation of scientists by offering high-quality educational programmes to master and PhD students as well as postdoctoral researchers. Our mission is to lead, from the vantage point of molecular science, cross-strategies for solving major social and economic challenges, such as climate change and sustainable supply of energetic and raw materials, thereby contributing to the establishment of a knowledge-based economy and improving quality of life for all. Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates.

Avinguda Països Catalans 16 Tarragona, Tarragona, 43007 SpainFounded in 2000 by the Government of Catalonia, the Institute of Chemical Research of Catalonia started its research activities in 2004. ICIQ is committed to performing excellent research at the frontier of knowledge in two main areas: Catalysis, Med Chem, Materials and Renewable Energy. The institute also has two other commitments: knowledge and technology transfer to the chemical, pharmaceutical and energy industrial sectors and that of training the future generation of scientists by offering high-quality educational programmes to master and PhD students as well as postdoctoral researchers. Our mission is to lead, from the vantage point of molecular science, cross-strategies for solving major social and economic challenges, such as climate change and sustainable supply of energetic and raw materials, thereby contributing to the establishment of a knowledge-based economy and improving quality of life for all. Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates.

Avinguda Països Catalans 16 Tarragona, Tarragona, 43007 SpainFounded in 2000 by the Government of Catalonia, the Institute of Chemical Research of Catalonia started its research activities in 2004. ICIQ is committed to performing excellent research at the frontier of knowledge in two main areas: Catalysis, Med Chem, Materials and Renewable Energy. The institute also has two other commitments: knowledge and technology transfer to the chemical, pharmaceutical and energy industrial sectors and that of training the future generation of scientists by offering high-quality educational programmes to master and PhD students as well as postdoctoral researchers. Our mission is to lead, from the vantage point of molecular science, cross-strategies for solving major social and economic challenges, such as climate change and sustainable supply of energetic and raw materials, thereby contributing to the establishment of a knowledge-based economy and improving quality of life for all. Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates.

Avinguda Països Catalans 16 Tarragona, Tarragona, 43007 SpainFounded in 2000 by the Government of Catalonia, the Institute of Chemical Research of Catalonia started its research activities in 2004. ICIQ is committed to performing excellent research at the frontier of knowledge in two main areas: Catalysis, Med Chem, Materials and Renewable Energy. The institute also has two other commitments: knowledge and technology transfer to the chemical, pharmaceutical and energy industrial sectors and that of training the future generation of scientists by offering high-quality educational programmes to master and PhD students as well as postdoctoral researchers. Our mission is to lead, from the vantage point of molecular science, cross-strategies for solving major social and economic challenges, such as climate change and sustainable supply of energetic and raw materials, thereby contributing to the establishment of a knowledge-based economy and improving quality of life for all. Crysforma provides complete scientific support for the discovery, analysis and scale-up of polymorphs, hydrates, amorphous phases, salts and co-crystals of active pharmaceutical ingredients or intermediates.

Astondo Bidea 612 Derio, Bizkaia, 48160 SpainHAWK Biosystems (formerly FASTBASE Solutions) has developed QF-Pro®, a transformative bio-imaging platform that precisely quantifies protein-protein interactions and protein post-translational modifications in patient pathology samples and cell lines, with an unprecedented degree of specificity, sensitivity, and insight to tumour heterogeneity. Unveiling these molecular phenomena in the TME provides with a new family of biologically relevant informative biomarkers based on protein function and opens whole new avenues for improving the precision medicine agenda.

Parque Tecnológico de León Edificio de Usos Comunes C/ Julia Morros s/n León, 24009 SpainGenhelix offers GMP manufacturing and quality control services to support production of recombinant proteins, antibodies, and other therapeutic drugs.

Avinguda Cami Reial, 51-57 08184 Palau-Solita, Plegamans (Barcelona) EspañaGrupo Uriach specializes in the health sector producing pharmaceuticals specialties, over the counter drugs and generic medicines.

39 Avinguda de Valencia Benimuslem, Comunidad Valenciana, 46611 SpainGMW Bioscience is a CRO based in the Southeastern of Spain (Valencia), one of the most important Spanish agricultural areas. However GMW also covers the North of Spain with its activities through a test site located in Santiago de Compostela and other regions from the Valencian head quarter. The personnel (mainly formed by agricultural scientists and biologists) has recognized experience in the conduct of efficacy trials, with wide experience in the efficacy of biological products, residues in plant, soil dissipation and soil accumulation as well as eco­toxicological studies conducted in compliance with current European guidelines (OECD, SETAC, EPPO, CEB, etc.). GMW conducts Field Residue trial in all regions of Spain in all major as well as in minor crops. Through GLP Environmental fate studies GMW investigates the interactions between compounds and environment. Soil dissipation studies provide estimates of the time needed for 50% or 90% dissipation (DT50 or DRT90) of the active ingredient under field conditions. GMW also carries out field and semi­field studies on honey bees under GLP to assess general effects of plant protection products on bees or to investigate more specific questions such as the impact on the brood development in honey bee colonies exposed to treatments as well as the long­term development of exposed colonies. This kind of studies is conducted in cooperation with our German partner, IBACON. A record in the last years of more than 450 successfully conducted efficacy trials, residue studies, and others provides you a clear picture of GMW significance as CRO providing services for the European industry.

Edificio Tecnológico Camino de Labiano 45b bajo 31192, Mutilva Alta (Navarra)-SpainGeiser Pharma offers pharmaceutical development, clinical studies, regulatory affairs and licensing.

c/ Isaac Peral 17 - Polígon Camí Ral · 08850 Gavà (Barcelona) - SpainGP Pharm offers research, development production and marketing of injectable products within Urology and Oncology fields.

Parque Tecnológico, Ed. 202. 48170 Zamudio (Bizkaia) SPAINGaiker provides services and expertise in biotechnology, environment and recycling, plastics, and nanoparticles.

Parque Empresarial de Touro Parcelas 26-27, Fonte Díaz Touro, A Coruña, 15822 SpainGalChimia is a CRO that offers specialized services in Discovery, Process, and Analytical Chemistry for the pharma, biotech, and agrochemical industries. Founded in 2001, GalChimia has become a European referent in Organic Synthesis thanks to the dedication and passion for chemistry of its team. Our range of services covers all the stages of product development: Discovery Chemistry: We design, evaluate and develop new routes of synthesis for the production of New Chemical Entities. GalChimia provides support for the Hit-To-Lead and Lead Optimization phases of Drug Development, but we also supply scaffolds, building blocks, focused libraries, reference standards, metabolites, and impurities. Process Chemistry: We design and optimize economical, reproducible and scalable synthetic routes for industrial production. This service includes a detailed examination of the state of the art, the development of non-infringement routes, evaluation of critical parameters, optimization of the reaction variables, and the development of analytical methods. Analytical Chemistry: We provide full analytical support both internally and in response to external requests: full characterization of chemical products, screening/development/validation of analytical methods, chiral and achiral separations, identi¬fication of impurities, accelerated stability studies.

PCB Parc Científic de Barcelona c/Baldiri Reixac, 4-12 i 15, Carrer de Baldiri Reixac, 15 Barcelona, Cataluña, 08028 SpainGalChimia is a CRO that offers specialized services in Discovery, Process, and Analytical Chemistry for the pharma, biotech, and agrochemical industries. Founded in 2001, GalChimia has become a European referent in Organic Synthesis thanks to the dedication and passion for chemistry of its team. Our range of services covers all the stages of product development: Discovery Chemistry: We design, evaluate and develop new routes of synthesis for the production of New Chemical Entities. GalChimia provides support for the Hit-To-Lead and Lead Optimization phases of Drug Development, but we also supply scaffolds, building blocks, focused libraries, reference standards, metabolites, and impurities. Process Chemistry: We design and optimize economical, reproducible and scalable synthetic routes for industrial production. This service includes a detailed examination of the state of the art, the development of non-infringement routes, evaluation of critical parameters, optimization of the reaction variables, and the development of analytical methods. Analytical Chemistry: We provide full analytical support both internally and in response to external requests: full characterization of chemical products, screening/development/validation of analytical methods, chiral and achiral separations, identi¬fication of impurities, accelerated stability studies.

15823 O Pino A Coruña, SpainGalChimia is a CRO that offers specialized services in Discovery, Process, and Analytical Chemistry for the pharma, biotech, and agrochemical industries. Founded in 2001, GalChimia has become a European referent in Organic Synthesis thanks to the dedication and passion for chemistry of its team. Our range of services covers all the stages of product development: Discovery Chemistry: We design, evaluate and develop new routes of synthesis for the production of New Chemical Entities. GalChimia provides support for the Hit-To-Lead and Lead Optimization phases of Drug Development, but we also supply scaffolds, building blocks, focused libraries, reference standards, metabolites, and impurities. Process Chemistry: We design and optimize economical, reproducible and scalable synthetic routes for industrial production. This service includes a detailed examination of the state of the art, the development of non-infringement routes, evaluation of critical parameters, optimization of the reaction variables, and the development of analytical methods. Analytical Chemistry: We provide full analytical support both internally and in response to external requests: full characterization of chemical products, screening/development/validation of analytical methods, chiral and achiral separations, identi¬fication of impurities, accelerated stability studies.

Servicio General de Citometria Paseo San Vincente s/n Salamanca E-37007 SpainHospital Universitario de Salamanca offers phenotypic distinction between cells, tumor/disease studies, cell proliferation, and analytical techniques.

Crossing da Choupana S / N, 15706 Santiago de Compostela, SpainThe Health Research Institute of Santiago (IDIS), created in January 2008, is one of the 13 health research institutes accredited in the whole of Spain by the Carlos III Health Institute and the only one in Galicia. The IDIS is a system of innovation and knowledge transfer plays a key part in translational matters and optimizes and expands the historical collaboration and synergistic potential between the University of Santiago de Compostela and the Santiago University Hospital Complex, entities to whom over 50 groups from the Institute are linked. The mission of the IDIS is to facilitate effective innovation in health services through the management of biomedical knowledge created by its 500 researchers. These strong capabilities have come to fruition through the development of a high level research within the hospital supported by IDICHUS Foundation, which manages and potentiates the Hospital Complex and IDIS research.

Avda. Barcelona, 69 Sant Joan Despí Barcelona, 08970 SpainInvent Farma offers manufacturing services.

Parc Científic de Barcelona C/ Baldiri Reixac 10 08028 Barcelona - SpainInstitute for Research in Biomedicine Barcelona provides MS, protein analysis, mass determination, and proteomics services.

Barcelona, CT SpainInstitute for Research in Biomedicine Barcelona provides MS, protein analysis, mass determination, and proteomics services.

Parque Tecnológico de Ciencias de la Salud Avenida del Conocimiento, 17 Armilla, Granada, 18016 SpainThe objectives of the research activity are aimed to the understanding of processes and the study of organisms of biomedical interest with a special emphasis in molecular parasitology, immunology and the development of new therapeutic strategies and procedures for diagnostic of diseases of world-wide impact.The development of new compounds and tools for the treatment of infectious diseases, the design of new procedures for diagnostic and the understanding of the molecular bases of infectious diseases, immune or neurodegenerative diseases or cancer are all important goals of the institute. All the pathologies studied at the IPBLN constitute important health problems, e.g. autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus or Crohn disease; neurodegenerative diseases like Parkinson or multiple sclerosis; and infectious diseases like tropical diseases, AIDS or hepatitis C, among others. The IPBLN offers a great potential in the field of biomedical sciences, in its allocation at the PTS is prepared for significant interaction with private enterprises, and other public research institutes. An atmosphere of mutual collaboration and interaction with other countries is reflected by the participation of the IPBLN scientists in international networks and projects. The relationship with Latin-American and European countries is especially relevant. The Institute also develops an important teaching role participating in postgraduate courses and accommodating many PhD students. In addition the institute promotes different activities for the development and dissemination of scientific culture. The services provided by the core facilities are available not only to the personnel of the Institute but also to the general scientific community. The facilities include, among others: DNA sequencing, oligonucleotide synthesis, proteomic, and the library.

Joan Buscallà, 10 08173 Sant Cugat del Vallès Barcelona, SpainInterquim manufactures active ingredients for the pharmaceutical industry.

Av. Ragull, 60 08173 Sant Cugat del Vallès Barcelona, SpainInterquim manufactures active ingredients for the pharmaceutical industry.

Barcelona, CT SpainInterquim manufactures active ingredients for the pharmaceutical industry.

Barcelona, Spain

Granada, SpainIntegromics provides software solutions for data management and analysis in genomics, proteomics, and drug discovery.

Polígono Mocholí Noain, 31110 SpainIDIFARMA is an independent, privately-owned pharmaceutical Contract Development and Manufacturing Organization based in Spain and specialized in highly potent drugs since 2001. With an experienced staff of 120+ people and over 100 international clients, IDIFARMA provides a full range of services covering most of the lifecycle of any pharmaceutical product from first pre-formulation trials to commercial manufacturing: drug formulation, development and validation of analytical methods, quality control and batch release in the EU, stability studies, regulatory affairs, GMP contract manufacturing and packaging for clinical or commercial use. Our state-of-the-art facility features a purpose-built high containment plant for GMP manufacturing of oral solid dosage forms, for both highly potent and non-potent drugs. IDIFARMA's expertise, capabilities and proven track record make it the perfect partner for the development of your projects.

Polígono Mocholí, C/ Noáin 1 Noáin, Navarre, 31110 SpainIDIFARMA is an independent, privately-owned pharmaceutical Contract Development and Manufacturing Organization based in Spain and specialized in highly potent drugs since 2001. With an experienced staff of 120+ people and over 100 international clients, IDIFARMA provides a full range of services covering most of the lifecycle of any pharmaceutical product from first pre-formulation trials to commercial manufacturing: drug formulation, development and validation of analytical methods, quality control and batch release in the EU, stability studies, regulatory affairs, GMP contract manufacturing and packaging for clinical or commercial use. Our state-of-the-art facility features a purpose-built high containment plant for GMP manufacturing of oral solid dosage forms, for both highly potent and non-potent drugs. IDIFARMA's expertise, capabilities and proven track record make it the perfect partner for the development of your projects.

5 Carretera Jumilla Blanca, Región de Murcia, 30540 Spainfield trials

Basque, SpainIMG Pharma Biotech focuses on drug discovery using not only conventional methods such as radioligand binding and autoradiography but also proprietary High Throughput Screening technology based on cell membrane microarrays.

Castillo de Monteagudo 7. Ofialia (Oficina 46) Pol. Ind. Base 2000. 30564 Lorquí. MurciaAn effective working methodology We adapt ourselves to the needs of each customer, making available to him the tools necessary to achieve his goals. We develop real projects to solve real-life problems. We use an organized approach and methodology in our work, under a system of process standardization. We work under strict confidentiality rules, so that the privacy of our customers´ data is guaranteed. We strive to optimize time and costs while complying with the deadlines established for every project.

IRTA Torre Marimon 08140 Caldes de Montbui (Barcelona)IRTA is a research institute owned by the Government of Catalonia adscribed to the Department of Agriculture. It is regulated by Law 04/2009, passed by the Catalan Parliament on 15 April 2009, and it is ruled by private regulations. IRTA's purpose is to contribute to the modernization, competitiveness and sustainable development of agriculture, food and aquaculture sectors, the supply of healthy and quality foods for consumers and, generally, improving the welfare of the population.

Sant Quintí , 77-79 Barcelona, Barcelona, 08041 SpainThe Research Institute, established on June 4, 1992, is a scientific foundation whose mission is to promote basic, clinical, epidemiological, and healthcare research in health sciences and biomedicine. The main aims of the Institute are to improve people’s health and quality of life through the production and dissemination of scientific knowledge, training of researchers at the international level, the generation of healthcare innovations, and the application of advances in care practices and health policies. The Institute, located on the Sant Pau Campus, is a biomedical research centre of excellence. It has been affiliated with the Autonomous University of Barcelona (UAB) since 2009 and it has been a member of the CERCA system in Catalonia since 2011. The Institute has its own team of researchers as well as affiliated researchers. These investigators conduct their research work in multidisciplinary groups, performing both basic and clinical research, in collaboration with researchers from other “sister” organizations located on the Sant Pau campus and the surrounding area. As a result, all research advances are visible under the IIB Sant Pau brand. Since 2011, the Institute has been recognized as a high-level health research centre whose objectives are to develop new techniques and processes through innovation in health care.

Av. Rafael Casanova, 81 08100 Mollet del Vallés, SpainSince 1935, we at IQV have had one ambition: to provide farm owners the most effective and sustainable solutions for protecting their crops. This goal compels us each day to produce, formulate and distribute a wide range of copper compound and Metalaxyl-based technical products and formulations. Our commitment to service, innovation and top quality has made us a leading global producer of fungicides for agricultural use, with an established presence in over 55 countries on all 6 continents. We have two production plants in Spain, one in Mollet del Vallés (Barcelona) and another in Cheste (Valencia), which have the capacity to produce 30,000 tonnes of copper-based active technical ingredients a year, as well as 30,000 tonnes of formulations for both own-brand packaging and that of other industry companies.

IRB Barcelona c. Baldiri Reixac, 10-12 E-08028 BarcelonaThe Advanced Digital Microscopy Core Facility is a joint unit of the IRB Barcelona and the Barcelona Science Park (PCB). It was Inaugurated in January 2009 and offers 24/7 access and support to 16 state-of-the-art and conventional imaging instruments for biological research, from high throughput screening widefield and confocal/multiphoton microscopy, to emerging techniques for cell manipulation and 3D imaging.

Barcelona, CT SpainThe Advanced Digital Microscopy Core Facility is a joint unit of the IRB Barcelona and the Barcelona Science Park (PCB). It was Inaugurated in January 2009 and offers 24/7 access and support to 16 state-of-the-art and conventional imaging instruments for biological research, from high throughput screening widefield and confocal/multiphoton microscopy, to emerging techniques for cell manipulation and 3D imaging.

Parque Tecnológico de Bizkaia Edificio 502, Primera Planta 48160 – Derio – Bizkaia SpainInnoprot is an innovative company provider of cell-based assays for High Throughput Screening, High Content Analysis and phenotypic Screening. Human and animal primary cells are also available at Innoprot. Innoprot develops and is commercializing proprietary multiplexed cell‐based assays using fluorescent biosensors for GPCR screening. This technology, called Nomad Biosensors, allows the measurement in a single assay of the different pathways involving drug target activation, β‐Arrestin recruitment & 2nd messenger release (Ca++, cAMP or DAG). This multiplex approach increases the characterization level of your compounds, reducing time, costs and handling requirements. In vitro disease models for Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis and Stroke are also available at Innoprot.

Innoprot, Parque Tecnológico de Bizkaia Edificio 502, Primera Planta Derio, Bizkaia, 48160 SpainInnoprot is an innovative company provider of cell-based assays for High Throughput Screening, High Content Analysis and phenotypic Screening. Human and animal primary cells are also available at Innoprot. Innoprot develops and is commercializing proprietary multiplexed cell‐based assays using fluorescent biosensors for GPCR screening. This technology, called Nomad Biosensors, allows the measurement in a single assay of the different pathways involving drug target activation, β‐Arrestin recruitment & 2nd messenger release (Ca++, cAMP or DAG). This multiplex approach increases the characterization level of your compounds, reducing time, costs and handling requirements. In vitro disease models for Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis and Stroke are also available at Innoprot.

Parque Científico de BarcelonaKymos Pharma Services offers drug analysis, validation, toxicokinetics, BE/BA studies, interaction studies, and analytical services.

Ronda Can Fatjó 5, Building D Cerdanyola del Vallès, Barcelona, 08290 SpainKymos is an analytical CRO devoted to bioanalysis and CMC services for small molecules, biologics and nucleic acids. We are GMP and GLP certified and we have been inspected by EMA and FDA. We work for biotechnology, pharmaceutical, veterinary, fine chemistry, cosmetics and nutraceutical industries. We are located in Cerdanyola del Vallès (Technology Park) where we have a two stand alone buildings: one of 1,500 m2 for laboratories and a second one of 1,000 m2 for offices. Our labs are fully equipped with state-of-the-art technology. The company has two subsidiaries: Pharmaprogress s.r.l. in Italy and Prolytic GMbH in Germany, as well as partnership agreements and collaborations with a wide range of local and multinational companies. Our main areas of activity are: BIOANALYSIS: - Full bioequivalence studies for generics - Bioanalysis of preclinical and clinical samples by mass spec (pK, PD, TK) - Bioanalysis by ELISA and ECLA for biologics and biosimilars - Immunogenicity studies - Cell based assays - Enzyme activity - Nucleic acid bioanalysis by qPCR - Full Preclinical studies CMC: - Analytical Method development and Validation - API analysis (compendial and non-compendial methods) - Stability studies - Characterization of biologics following the ICH Q6B - Microbiology testing - Batch Testing & Batch Release

Calle Industria 29, Polígono Industrial Comte de Sert, 08755 Castellbisbal, Barcelona SpainLaboratorios Rubió provides medical devices, pharmaceutical specialties,diagnostics tests, genetic analysis and food supplements.

Crta. De l'Hospitalet, 34 Cornella, Barcelona 08940 SpainLEBSA supplies and manufactures API products.

Barcelona, CT SpainLEBSA supplies and manufactures API products.

Venus, 26 Terrassa, Barcelona 08228 SpainLABIANA Life Sciences offers quality assurance, quality control, and contract manufacturing services.

6 Calle de San Emilio Madrid, Comunidad de Madrid, 28017 SpainWe, León Research, are a Spanish CRO, providing outsourcing services all over Europe for the Pharma Industry, Biotech companies, Medical Devices Manufacturers, Food Industry and other CROs, with a wide experience on clinical research, developing Phase I to IV clinical trials, medical devices, observational and food studies. As a full service Contract Research Organization, our solutions include all the activities from design, setting up and monitoring of clinical trials and research studies, up to the management of data, statistical analysis and medical writing, covering the whole process to introduce new medical devices and pharmacy products on the market. In Leon research, we promote intelligence and creativity as the two key factors on scientist research and we also believe that quality, in the framework of the GCP/ICH, as well as flexibility to adapt our services, are what warranties the success. We know better how to manage global studies, because by conducting local clinical trials, we can offer a better local knowledge which accelerates and facilitates the final result.

Julia Morros s/n Edif. Usos Comunes, Local 1 Parque Tecnológico León, Castilla y León, 24009 SpainWe, León Research, are a Spanish CRO, providing outsourcing services all over Europe for the Pharma Industry, Biotech companies, Medical Devices Manufacturers, Food Industry and other CROs, with a wide experience on clinical research, developing Phase I to IV clinical trials, medical devices, observational and food studies. As a full service Contract Research Organization, our solutions include all the activities from design, setting up and monitoring of clinical trials and research studies, up to the management of data, statistical analysis and medical writing, covering the whole process to introduce new medical devices and pharmacy products on the market. In Leon research, we promote intelligence and creativity as the two key factors on scientist research and we also believe that quality, in the framework of the GCP/ICH, as well as flexibility to adapt our services, are what warranties the success. We know better how to manage global studies, because by conducting local clinical trials, we can offer a better local knowledge which accelerates and facilitates the final result.

3F San-Ei BldgLabcyte provides drug discovery, genomics, assays, genetic services, and spectrometry.

Terrassa, CT SpainLEITAT is a Technology Centre, TECNIO member and recognized by the Ministry of Science and Innovation, which aims to collaborate with companies and institutions both adding technological value to the products and processes, and focuses its work in research, development and industrial innovation.

Avenida Jaime I El Conquistador, 66 Torre Jordi, Piso 12D El Campello, Alicante, 03560 SpainLucentum Analytics is a partnership formed by two career neuroscientists. We provide neuroscientific data analysis and consulting services for many types of neural data, including EEG, electrophysiology, and behavior.

2 Carrer de Baldiri Reixac Barcelona, CT, 08028 SpainLeanbio Pro is a Contract Development and Manufacture Organization for biopharmaceutical products (CDMO). We offer client tailored solutions in mammalian cell lines, plants, yeast and bacteria, providing a straightforward CMC program in accordance with ICH guidelines. We help in the manufacture of new biological entities and biosimilars, supporting POC, non-clinical and clinical trials and market supply.

2 Carrer de Baldiri Reixac Cluster II. Av. Dr. Marañón 8 Barcelona, CT, 08028 SpainLeanbio Pro is a Contract Development and Manufacture Organization for biopharmaceutical products (CDMO). We offer client tailored solutions in mammalian cell lines, plants, yeast and bacteria, providing a straightforward CMC program in accordance with ICH guidelines. We help in the manufacture of new biological entities and biosimilars, supporting POC, non-clinical and clinical trials and market supply.

calle General Martinez Campos, 46 Madrid, Madrid, 28010 SpainLife Length provides the most advanced and accurate services focused on telomere biology as well as assays to determine multiple other biomarkers. We offer a wide variety of research services based on in vitro and in vivo assays. Our corporate leader clients worldwide trust us to contribute to their projects with tailored biomarker solutions. We are experts in the determination of telomere length and telomerase activity biomarkers providing access to more than 250 telomere length variables. Additionally, we have a wide portfolio of assays to determine hundreds of other biomarkers (cytokines, RNA labelling, proteins, etc.) - TAT: Our proprietary technology for the analysis of the whole telomere length distribution - QTRAP assay: Determination of telomerase activity - hTERT expression: human telomerase gene expression analysis - RNAscope™: Detection of any mRNA within intact cells and tissues. Labell and measure telomere length in scpecific cellular populations. - Q-FISH: Upgraded senescence and oxidative stress analysis with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

Calle de Miguel Angel 11 Madrid, Madrid, 28010 SpainLife Length provides the most advanced and accurate services focused on telomere biology as well as assays to determine multiple other biomarkers. We offer a wide variety of research services based on in vitro and in vivo assays. Our corporate leader clients worldwide trust us to contribute to their projects with tailored biomarker solutions. We are experts in the determination of telomere length and telomerase activity biomarkers providing access to more than 250 telomere length variables. Additionally, we have a wide portfolio of assays to determine hundreds of other biomarkers (cytokines, RNA labelling, proteins, etc.) - TAT: Our proprietary technology for the analysis of the whole telomere length distribution - QTRAP assay: Determination of telomerase activity - hTERT expression: human telomerase gene expression analysis - RNAscope™: Detection of any mRNA within intact cells and tissues. Labell and measure telomere length in scpecific cellular populations. - Q-FISH: Upgraded senescence and oxidative stress analysis with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

Calle Faraday 7, Campus de Cantoblanco Parque Científico de Madrid Madrid, Madrid, 28049 SpainLife Length provides the most advanced and accurate services focused on telomere biology as well as assays to determine multiple other biomarkers. We offer a wide variety of research services based on in vitro and in vivo assays. Our corporate leader clients worldwide trust us to contribute to their projects with tailored biomarker solutions. We are experts in the determination of telomere length and telomerase activity biomarkers providing access to more than 250 telomere length variables. Additionally, we have a wide portfolio of assays to determine hundreds of other biomarkers (cytokines, RNA labelling, proteins, etc.) - TAT: Our proprietary technology for the analysis of the whole telomere length distribution - QTRAP assay: Determination of telomerase activity - hTERT expression: human telomerase gene expression analysis - RNAscope™: Detection of any mRNA within intact cells and tissues. Labell and measure telomere length in scpecific cellular populations. - Q-FISH: Upgraded senescence and oxidative stress analysis with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

Solana nº 26 28850 Torrejón de Ardoz Madrid - SpainMedinsa develops, produces, manufactures, packages and distributes solid oral dosage form pharmaceuticals.

Address: #250 D,Metropolis Healthcare offers clinical research services as well as pathology testing, DNA extraction, and specimen archival.

Avenida Fernando Abril Martorell 106, Torre A, Planta 6 (Lab 6.12) Valencia, Valencia, 46026 SpainThe Medical Research Institute Hospital La Fe (IIS La Fe) leads the research and innovation policy of the Health Department "Hospital La Fe", one of the largest and best qualified Hospitals in Europe with cutting-edge clinical technologies. The Medical Research Institute Hospital La Fe “promotes and develops quality translational research and health innovation, aimed at solving health challenges, increasing scientific and economic knowledge, and improving quality of life of society”. Since 2009, IIS La Fe is accredited by the Spanish Ministry of Science and Innovation as a "Health Research Institute", in recognition of the quality of its R&D and Innovation. +SCIENTIFIC MEMBERS+ IIS La Fe consists of 20 accredited research groups, each of which has at least 10 members including physicians, scientists and technicians, who develop a scientific strategic plan externally evaluated. Moreover, several Joint Research Units with reference research institutions are part of IIS La Fe: University of Valencia, Polytechnic University of Valencia, Principe Felipe Research Centre, and Spanish National Research Council (CSIC) +SERVICE PORTFOLIO+ IIS La Fe also offers scientific and technological services with advanced clinical and research facilities, to undertake research and innovation programmes based on state-of-the-art biomedical science.

Center for Omics Sciences (COS) – Universitat Rovira i Virgili Avinguda Universitat 3, 43204 – Reus, SpainThe Metabolomics Platform is a joint research facility created by URV and CIBERDEM. It also partners with the IISPV, a major medical research organization that undertakes numerous research initiatives in the country. The Metabolomics Platform is meant to provide a high quality service in the field of metabolomics for leading research groups in biomedicine. Expert support and consulting through all project steps are envisaged.

Pol. Ind. Celrà Avda. Pirineus 17460 Celrà (Girona) SPAINMedichem provides Active Pharmaceutical Ingredients (APIs) and contract manufacturing.

Fructuós Gelabert, 6-8 08970 Sant Joan Despí (Barcelona) SpainMedichem provides Active Pharmaceutical Ingredients (APIs) and contract manufacturing.

c/ Jacint Verdaguer, 62 08970 SANT JOAN DESPÍ Barcelona - SpainMicro-Bios is an Analysis and Quality Control Laboratory with a wide experience of over 35 years in the field of Industrial Analysis. The combination of this experience and our continuous updating processes enables us to provide our customers with what they need at all times. The Laboratory is geared to dealing with the specific Quality Control needs of each company on a full-time basis. Our organisation enables our customers to regard the laboratory as a unit of their own company, supplementing their own daily Quality Control procedures. Our activity involves the entire lifecycle of the product; from the raw materials to the intermediate process and products, and through to the finish product. Our wide range of services encompasses the physical-chemical and microbiological testing of single samples, the validation of analytical methods, the follow-up and validation of cleaning processes, environmental and surface controls, etc, in addition to training and advisory activities.

Edificio Severo Ochoa. Calle Fernando Bonguera SN Oviedo, Asturias, 33006 SpainWe provide solutions on intestinal microbiota through the isolation and storage of the microbiota in viable conditions, for further development of next generation biotherapeutics to improve human health. MICROBIOTA ANALYSES Composition and functionality of the microbiota using next generation sequencing technologies (NGS) coupled with bioinformatics. MICROBIOTA STORAGE Human Purified Microbiota (HPM) storage for therapeutic applications under strict privacy and quality control. BIOTHERAPEUTICS DEVELOPMENT Next generation biotherapeutics based on rationally defined bacterial consortia of human commensal microbes. GUTALIVE KIT. ANAEROBIC STOOL COLLECTION DEVICE Microbiome transport at room temperature (frozen chain no need to transport) is possible with GutAlive, a kit that ensures anaerobic condition and helps to normalize and standardize microbiome studies

Calle los Prados, 166 (Parque Tecnológico de Gijón) Gijón, Asturias, 33203 SpainWe provide solutions on intestinal microbiota through the isolation and storage of the microbiota in viable conditions, for further development of next generation biotherapeutics to improve human health. MICROBIOTA ANALYSES Composition and functionality of the microbiota using next generation sequencing technologies (NGS) coupled with bioinformatics. MICROBIOTA STORAGE Human Purified Microbiota (HPM) storage for therapeutic applications under strict privacy and quality control. BIOTHERAPEUTICS DEVELOPMENT Next generation biotherapeutics based on rationally defined bacterial consortia of human commensal microbes. GUTALIVE KIT. ANAEROBIC STOOL COLLECTION DEVICE Microbiome transport at room temperature (frozen chain no need to transport) is possible with GutAlive, a kit that ensures anaerobic condition and helps to normalize and standardize microbiome studies

Calle los Prados, 166 (Parque Tecnológico de Gijón) Gijón, Asturias, 33203 SpainWe provide solutions on intestinal microbiota through the isolation and storage of the microbiota in viable conditions, for further development of next generation biotherapeutics to improve human health. MICROBIOTA ANALYSES Composition and functionality of the microbiota using next generation sequencing technologies (NGS) coupled with bioinformatics. MICROBIOTA STORAGE Human Purified Microbiota (HPM) storage for therapeutic applications under strict privacy and quality control. BIOTHERAPEUTICS DEVELOPMENT Next generation biotherapeutics based on rationally defined bacterial consortia of human commensal microbes. GUTALIVE KIT. ANAEROBIC STOOL COLLECTION DEVICE Microbiome transport at room temperature (frozen chain no need to transport) is possible with GutAlive, a kit that ensures anaerobic condition and helps to normalize and standardize microbiome studies

Parc Científic de Barcelona C/ Baldiri Reixac, 4 08028 Barcelona SpainMind the Byte is a bioinformatics company that develops and provides software for computational drug discovery using Big Data and Machine Learning (AI) approaches. We work with partners on a consultancy basis or offer an easy to use Software as a Service (SaaS) package to allow clients to apply the High-performance computing platform on a flexible pay-per-use basis without investment in hardware or software licenses. Mind the Byte has developed a versatile set of applications using cloud computing which lowers the entry barrier to the technology, e.g. i) virtual profiling methods to facilitate the identification of targets and mechanisms of action of phenotypic screening hits or natural products with reported activity ii) virtual screening methods to identify compounds acting on a specific target by mining internal or commercial compound libraries, to expand hit or lead series and to conduct repurposing of known drugs. iii) MtBDock - a fully integrated docking protocol reducing the amount of false positives by incorporation of all prosthetic groups and conformational minimization iv) SmartDock - an experimentally validated docking protocol with further improved performance based on machine learning of PDB target-ligand interactions Mind the Byte is an Amazon Web Services technology partner - a seal of quality that has only been awarded to five companies in this sector – to ensure security and reliability. The company was founded in 2011 by Alfons Nonell-Canals, a specialist in computer-aided drug design and in large-scale chemical and biological analyses, and has since expanded with an experienced staff.

Diputació 279 España Barcelona, I am not in the U.S. or Canada, 08007 SpainMind the Byte is a bioinformatics company that develops and provides software for computational drug discovery using Big Data and Machine Learning (AI) approaches. We work with partners on a consultancy basis or offer an easy to use Software as a Service (SaaS) package to allow clients to apply the High-performance computing platform on a flexible pay-per-use basis without investment in hardware or software licenses. Mind the Byte has developed a versatile set of applications using cloud computing which lowers the entry barrier to the technology, e.g. i) virtual profiling methods to facilitate the identification of targets and mechanisms of action of phenotypic screening hits or natural products with reported activity ii) virtual screening methods to identify compounds acting on a specific target by mining internal or commercial compound libraries, to expand hit or lead series and to conduct repurposing of known drugs. iii) MtBDock - a fully integrated docking protocol reducing the amount of false positives by incorporation of all prosthetic groups and conformational minimization iv) SmartDock - an experimentally validated docking protocol with further improved performance based on machine learning of PDB target-ligand interactions Mind the Byte is an Amazon Web Services technology partner - a seal of quality that has only been awarded to five companies in this sector – to ensure security and reliability. The company was founded in 2011 by Alfons Nonell-Canals, a specialist in computer-aided drug design and in large-scale chemical and biological analyses, and has since expanded with an experienced staff.

Parque Tecnologico, 801A Derio, 48160 SpainNoray Bioinformatics provides bioinformatics and software for scientific studies.

Aribau 171 08036 BarcelonaNexus Oncology offers data management, site selection, project management, and drug development consultancy to support studies in oncology.

1 Edificio BIC 18100 Armilla, Granada, SpainNeuron Biopharma specializes in development of neuroprotectants and bioprocesses.

Benaguasil/Valencia, SpainNoldus Information Technology develops software and technology in the application of tracking animal behavior.

Avenida Isla Graciosa 3 San Sebastian del los Reyes, Madrid, 28703 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Calle Faraday 7 Parque Científico de Madrid Madrid, Madrid, 28049 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Calle Anabel Segura 16 Edificio Vega Norte - Ed. 3 1ª planta Alcobendas, Madrid, 28108 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Parque científico de Madrid - C/Faraday, 7 (Campus de Cantoblanco) Madrid, 28049 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Madrid, Community of Madrid SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

c/ Faraday 7 Madrid, Madrid, 28049 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Carrer d'Urgell 240 2-D Oblikue Consulting, S.L. Barcelona, Barcelona, 08036 SpainHealth Economics and Market Access Consultancy company based in Barcelona and focused in the Spanish Healthcare market.

Calle Sant Ferran 74Oryzon offers custom microarrays, transcriptomics, toxicity studies, and molecular screening services for the fields of toxicogenomics, pharmacogenetics, and agrobiotechnology.

Calle del Doctor Fleming, 51 - 1 Madrid, Madrid, 28036 SpainOXON Epidemiology is a full-service global scientific and operational provider specialising in the generation of Real-World Evidence (RWE) via primary data collection and database observational studies. As a leader CRO in global field, database, and hybrid observational studies in all major therapeutic areas, we conduct non-interventional RWE and late-phase studies in support of leading pharmaceutical, biotechnology and medical device industries, providing real-world evidence (RWE) solutions for safety, market access, drug development and marketing through the design and execution of global, regional and single-country studies in the peri and post-approval space. We apply world-class epidemiological & operational experience, and innovative technologies to help clients worldwide obtain high-quality RWD for improving patients' and public health. Our philosophy is to integrate clinical, safety, patient-reported outcomes, health economic, methodological and statistical thinking and insights to maximise value and provide solutions for our clients. Our specialization, high calibre and the complementary skills of people in OXON allow us to have a clear focus, deep expertise, superior insight, high standards and innovation to provide concrete results with maximum value to our clients. On the other hand, our size allows us to be flexible and keep high-quality people close to our clients, and our long-term alliances permit us to compete with the biggest CROs. We have strong links with The Medical Statistics Department, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine and our leadership in ENCePP activities, such as data integration and HTA allows us to have good relationships with EU regulators and leading academic pharmacoepidemiologists. OXON collaborates with academics and clinicians in a not-for-profit international programme to evaluate non-randomised comparative studies of treatments for COVID-19 and prognostic factors and organizes masterclasses and webinar series by leading academic pharmacoepidemiologists in key EU and Asian countries to help clients design and conduct high-quality field and database observational studies.

Parque Tecnológico de Bizkaia Edif. 502, planta 0 Derio, Bizkaia, 48160 SpainThe activity of the company is centered in the area of health and its objective is to identify, validate, patent and commercialize early diagnostic and/or prognostic systems, as well as therapeutic targets of hepatic diseases and other great prevalence complex pathologies. To accomplish this we use, metabolomics and bioinformatics and have established a complete and highly productive platform which supports the advance of our developments.

101 Ibaizabal Bidea Building 502 Floor 0 Zamudio, PV, 48170 SpainThe activity of the company is centered in the area of health and its objective is to identify, validate, patent and commercialize early diagnostic and/or prognostic systems, as well as therapeutic targets of hepatic diseases and other great prevalence complex pathologies. To accomplish this we use, metabolomics and bioinformatics and have established a complete and highly productive platform which supports the advance of our developments.

Parque Tecnológico de Bizkaia 502 Building 48160 Derio SpainThe activity of the company is centered in the area of health and its objective is to identify, validate, patent and commercialize early diagnostic and/or prognostic systems, as well as therapeutic targets of hepatic diseases and other great prevalence complex pathologies. To accomplish this we use, metabolomics and bioinformatics and have established a complete and highly productive platform which supports the advance of our developments.

Parque Tecnologico de Bizkaia Edificio 502 planta 0 Derio, Bizkaia, 48160 SpainThe activity of the company is centered in the area of health and its objective is to identify, validate, patent and commercialize early diagnostic and/or prognostic systems, as well as therapeutic targets of hepatic diseases and other great prevalence complex pathologies. To accomplish this we use, metabolomics and bioinformatics and have established a complete and highly productive platform which supports the advance of our developments.

Aljarafe street, 19 Industrial Park Coria del Río E-41100 – Coria del Río Seville (SPAIN)Phytest Hispania, S.L. was established in 2006 with the aim of providing the agricultural sector, and especially plant health & nutrition companies with Research and Development Technical Services, mainly of plant protection products and fertilizers. The company is formed by a group of young professionals with extensive experience in the field of plant health and agricultural experimentation. Phytest Hispania offers integral consulting services in the implementation of work plans aimed at the development and positioning of agronomic practices and plant protection products. The company has all the necessary resources to carry out the work with the highest quality and reliability. Phytest Hispania, S.L. holds the authorization to perform ‘Officially Recognized Trials’ granted by the Spanish Ministry of Agriculture, Food and Environment, with the certification E.O.R. No. 59/07. Our practice is not limited to the mere systematic execution of the projects that we are committed to, since we think that the best way to optimize the resources invested by our clients is adapting our work to their interests, so that it has a positive impact on the intended purpose. The meeting our commitments is currently recognized by several industry leaders that, year after year, have relied on us and increased our participation in the service of their interests. We at Phytest Hispania work with an entrepreneurial and dynamic spirit, whose main objective is to meet the highest expectations of our clients: Rigor and effectiveness. Timely execution of work. Confidentiality and Information Security. Regular communication with our clients. Highly competitive prices policy. Drafting of documents in Spanish or English.

Apartat 283 Ctra. del Canal Amposta - Sant Jaume, km.1 43870 - AMPOSTA (Tarragona), EspanaPROBODELT was born in 1995 with the objective of designing and carrying out programs for a reasonable sensible pest control. Since the very beginning, some strategies were developped and some methods were applied with very effective results. Probodelt’s approach, based on the integration of different control techniques and the fine tuning of simple application systems, has given this company a good reputation and has kept it worlwide at the cutting edge of technology. We are a state-of-the-art company as regards the development and application of strategies for pest control. We are experts on traps or insects: we investigate and develop new models, which we patent and manufacture directly. We develop together the fine tuning on the field of the different pheromones and other attractants from our suppliers. We supply top quality materials and we are constantly improving them. We are popular for making field tests in many different situations. Plagues presently being controlled with PROBODELT's techniques are the rice warm (Chilo suppressalis) in Catalonia (Ebro delta and Pals’ rice fields) and la Camargue (Roïne Delta, France), the Mediterranean fruit fly (Ceratitis capitata) in citrus and sweet fruit areas in Catalonia, País Valencià, Múrcia, Andalusia, Aragó and the Balear Islands, the artichoke borer (Gortyna xanthenes) in Catalonia, the (olive tree fly Bactrocera oleae) in the south of Catalonia and the diamondback moth (Plutella xylostella) in Catalonia.

Cornellà de Llobregat, CT, 08940 SpainPanlab develops software and manufactures systems in application of psychopharmacalogy, motor/sensory, and physiology services.

Carrer del Dr. Aiguader, 88, 08003 Barcelona, SpainThe seven centres located in the park conduct science of excellence in a wide diversity of fields, with a critical mass of 1,400 people hailing from 54 different countries, an accumulated R&D budget of approximately 80 M€ per year and cutting-edge scientific equipment. This allows us to explore, in a unique building, the most relevant questions in life sciences and biomedicine today, from the molecular up to the populational perspective. The physical connection of the PRBB with the Hospital de Mar next door also provides an excellent insight into clinical reality. This “factory of the future” produces knowledge that will be of the utmost importance for medicine in 20 or 30 years time. Each day we strive to remain competitive and incorporate scientific talent from the top American and European centres, meaning currently more than 37% of the scientific community is foreign. Our organisational model is cooperative, with common spaces that facilitate the interrelationship between the centres as well as having shared advanced scientific-technical services. The animal facility of the park is outstanding and considered to be one of the most modern in Europe, as are other services in the centres such as the advanced light microscopy, proteomics and flow cytometry units. We extend our thanks to the Government of Catalonia, Pompeu Fabra University and Barcelona City Council who made this initiative a reality in 2006. And also to you, for your interest in and support for science and biomedical research.

C/ Doctor Aiguader, 88 Barcelona, E-08003 SpainThe seven centres located in the park conduct science of excellence in a wide diversity of fields, with a critical mass of 1,400 people hailing from 54 different countries, an accumulated R&D budget of approximately 80 M€ per year and cutting-edge scientific equipment. This allows us to explore, in a unique building, the most relevant questions in life sciences and biomedicine today, from the molecular up to the populational perspective. The physical connection of the PRBB with the Hospital de Mar next door also provides an excellent insight into clinical reality. This “factory of the future” produces knowledge that will be of the utmost importance for medicine in 20 or 30 years time. Each day we strive to remain competitive and incorporate scientific talent from the top American and European centres, meaning currently more than 37% of the scientific community is foreign. Our organisational model is cooperative, with common spaces that facilitate the interrelationship between the centres as well as having shared advanced scientific-technical services. The animal facility of the park is outstanding and considered to be one of the most modern in Europe, as are other services in the centres such as the advanced light microscopy, proteomics and flow cytometry units. We extend our thanks to the Government of Catalonia, Pompeu Fabra University and Barcelona City Council who made this initiative a reality in 2006. And also to you, for your interest in and support for science and biomedical research.

BIOPARCPolyplus-transfection offers their proprietary transfection reagents and in vivo reagents for purchase.

10 Carrer de Baldiri Reixac Barcelona Science Park Barcelona, CT, 08028 Spain

Parque Tecnológico de Bizkaia Edificio 801-A, 1ª Planta Derio, Vizcaya 48160, SpainPharmakine offers analytical services, drug testing, histology, cytogenetics, tumor models, therapy response, and mouse primary cells.

C/ Faraday, 7 28049 Madrid, SpainSince our inception over twenty years ago, we have focused on developing a technical, administrative, and human resources infrastructure with a single purpose: to provide integrated quality, productivity and compliance services to highly-regulated manufacturers throughout the globe. To meet the needs of the times, we have integrated our services to make certain that all the compliance, risk-management, knowledge-management, and workforce needs of our global partners are addressed in ways that provide the desired operational and compliance result.

Avda. Europa, 19 - Edif. 1 - 2ª PlantaAt PRA Health Sciences, providing innovative solutions for our clients is what we do. But innovation just for the sake of innovation isn’t why we do it. Side-by-side with our clients, we strive to move drug discovery forward, to help them develop life-saving and life- improving drugs. We help change people’s lives for the better every single day. It’s who we are. Innovating to help people is at the heart of our process, but it’s even more than that. It’s also our privilege.

Sagasta 28Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

Ronda de Poniente 16, 1º A-F. Tres Cantos. 28760 Spain.ProAlt offers innovative proteins and antibodies and research services (CRO): protein expression, antibodies generation and recombinant antibodies production.

C / Ronda de Poniente, 16 - 1º AF Business Park EURONOVA Tres Cantos, Madrid, 28760 SpainProAlt offers innovative proteins and antibodies and research services (CRO): protein expression, antibodies generation and recombinant antibodies production.

1 Plaça de Pau Vila Barcelona, CT, 08039 SpainQuantum-Mechanics and Machine Learning Drug Discovery. Pharmacelera develops proprietary Computer-Aided Drug Design software and provides access to its technology through flexible licensing options and computational chemistry services. The methodology mines an unexploited chemical space, finding starting points with larger chemical diversity and improving the creativity of chemists. The technology is based on accurate Quantum-Mechanics algorithms, Machine Learning and High-Performance Computing (HPC) and it derives from more than 25 years of research. Pharmacelera helps companies in Target Identification, Hit-Identification, Hit-to-Lead and Lead Optimization drug discovery stages by finding novel hits, improving ligand binding properties (ADME, Tox, ...), obtaining insights of ligand / receptor interactions and identifying original backup compounds.

PCB, Torre R, 4a planta, Despatx A05 Parc Científic de Barcelona, Carrer de Baldiri Reixac, 4-8 Barcelona, Cataluña, 08028 SpainQuantum-Mechanics and Machine Learning Drug Discovery. Pharmacelera develops proprietary Computer-Aided Drug Design software and provides access to its technology through flexible licensing options and computational chemistry services. The methodology mines an unexploited chemical space, finding starting points with larger chemical diversity and improving the creativity of chemists. The technology is based on accurate Quantum-Mechanics algorithms, Machine Learning and High-Performance Computing (HPC) and it derives from more than 25 years of research. Pharmacelera helps companies in Target Identification, Hit-Identification, Hit-to-Lead and Lead Optimization drug discovery stages by finding novel hits, improving ligand binding properties (ADME, Tox, ...), obtaining insights of ligand / receptor interactions and identifying original backup compounds.

Pl. Pau Vila, 1 Barcelona, 08039 SpainQuantum-Mechanics and Machine Learning Drug Discovery. Pharmacelera develops proprietary Computer-Aided Drug Design software and provides access to its technology through flexible licensing options and computational chemistry services. The methodology mines an unexploited chemical space, finding starting points with larger chemical diversity and improving the creativity of chemists. The technology is based on accurate Quantum-Mechanics algorithms, Machine Learning and High-Performance Computing (HPC) and it derives from more than 25 years of research. Pharmacelera helps companies in Target Identification, Hit-Identification, Hit-to-Lead and Lead Optimization drug discovery stages by finding novel hits, improving ligand binding properties (ADME, Tox, ...), obtaining insights of ligand / receptor interactions and identifying original backup compounds.

103 Calle del Coso Zaragoza, Aragón, 50001 SpainPharmaLex is a leading provider of specialized services for the pharma, biotech and medical device industries. We guide you from early strategic planning activities and non-clinical requirements through clinical development, regulatory submission processes and post-approval / maintenance post-launch activities. Our experts use technology-enabled solutions to support you through the entire product lifecycle. We deliver exceptional results — going above and beyond the standard to deliver tailor-made solutions worldwide.

Torre Nozar c/Titán, 15 Mendez Alvaro 28045 Madrid SpainPPD offers central lab services, bioanalytical services, biomarker discovery services, assay development services, cGMP analytical services, CMC consulting, and pharmacology services.

Eduardo Primo Yúfera, 3 Valencia, Valencia, 46012 SpainPrince Felipe Research Centre (CIPF) focuses on research in regenerative medicine, protein chemistry, structural biochemistry, gene expression, and bioinformatics.

Barcelona, 08003 SpainqGenomics (Quantitative Genomic Medicine Laboratories) offers medical genetics services to support clinical studies.

Barcelona, CT SpainqGenomics (Quantitative Genomic Medicine Laboratories) offers medical genetics services to support clinical studies.

C/Faraday, 7 Madrid, 28049 SpainQuosPharma specializes in organic synthesis of API and offers expertise in synthesis design, process optimization, structural determination, derivative preparation, impurity preparation, compound characterization, and NMR.

Madrid, Community of Madrid SpainQuosPharma specializes in organic synthesis of API and offers expertise in synthesis design, process optimization, structural determination, derivative preparation, impurity preparation, compound characterization, and NMR.

Calle de Alfonso XII, 62 3rd floor, Office 3055 Madrid, Madrid, 28014 SpainTransforming imaging data into actionable predictions We design pioneering tools that unlock imaging data to improve patient outcomes. From clinical research to personalized care. Healthcare providers, biopharma companies, research and academic institutions and RWE specialists partner with Quibim to power up the imaging portion of their business, accelerating the arrival of precision medicine. Our unique multi-scale ways of seeing problems can guide decision-making at every stage in the drug development program. Quibim can reveal a full suite of novel imaging biomarkers from existing and new patient datasets to enhance the power of multi-omics: deeply analyze disease mechanisms, find the right candidates for clinical studies, stratify patients with different risks, predict patient outcomes and drug response and monitor treatment progress using a tissue-agnostic approach. As a global leader in medical imaging analysis and processing, our best-in-class software medical devices and solutions extract objective and highly accurate information versus traditional methods, using the latest AI technology. We have advanced image harmonization techniques generating a standardized image quality that minimizes variability across equipment manufacturers and acquisition protocols. Quibim has access to large scale databases and can analyze any image modality and any tissue from thousands of consecutive patients. *Please note that we do not analyze pathological images.

Via Augusta, 123 7th floor, office 708 Barcelona, Barcelona, 08006 SpainTransforming imaging data into actionable predictions We design pioneering tools that unlock imaging data to improve patient outcomes. From clinical research to personalized care. Healthcare providers, biopharma companies, research and academic institutions and RWE specialists partner with Quibim to power up the imaging portion of their business, accelerating the arrival of precision medicine. Our unique multi-scale ways of seeing problems can guide decision-making at every stage in the drug development program. Quibim can reveal a full suite of novel imaging biomarkers from existing and new patient datasets to enhance the power of multi-omics: deeply analyze disease mechanisms, find the right candidates for clinical studies, stratify patients with different risks, predict patient outcomes and drug response and monitor treatment progress using a tissue-agnostic approach. As a global leader in medical imaging analysis and processing, our best-in-class software medical devices and solutions extract objective and highly accurate information versus traditional methods, using the latest AI technology. We have advanced image harmonization techniques generating a standardized image quality that minimizes variability across equipment manufacturers and acquisition protocols. Quibim has access to large scale databases and can analyze any image modality and any tissue from thousands of consecutive patients. *Please note that we do not analyze pathological images.

EUROPA BUILDING Av/Aragon 30, Floor 13, Office I-J VALENCIA, Valencia, 46021 SpainTransforming imaging data into actionable predictions We design pioneering tools that unlock imaging data to improve patient outcomes. From clinical research to personalized care. Healthcare providers, biopharma companies, research and academic institutions and RWE specialists partner with Quibim to power up the imaging portion of their business, accelerating the arrival of precision medicine. Our unique multi-scale ways of seeing problems can guide decision-making at every stage in the drug development program. Quibim can reveal a full suite of novel imaging biomarkers from existing and new patient datasets to enhance the power of multi-omics: deeply analyze disease mechanisms, find the right candidates for clinical studies, stratify patients with different risks, predict patient outcomes and drug response and monitor treatment progress using a tissue-agnostic approach. As a global leader in medical imaging analysis and processing, our best-in-class software medical devices and solutions extract objective and highly accurate information versus traditional methods, using the latest AI technology. We have advanced image harmonization techniques generating a standardized image quality that minimizes variability across equipment manufacturers and acquisition protocols. Quibim has access to large scale databases and can analyze any image modality and any tissue from thousands of consecutive patients. *Please note that we do not analyze pathological images.

EUROPA BUILDING Av/Aragon 30, Floor 13, Office I-J VALENCIA, Valencia, 46021 SpainTransforming imaging data into actionable predictions We design pioneering tools that unlock imaging data to improve patient outcomes. From clinical research to personalized care. Healthcare providers, biopharma companies, research and academic institutions and RWE specialists partner with Quibim to power up the imaging portion of their business, accelerating the arrival of precision medicine. Our unique multi-scale ways of seeing problems can guide decision-making at every stage in the drug development program. Quibim can reveal a full suite of novel imaging biomarkers from existing and new patient datasets to enhance the power of multi-omics: deeply analyze disease mechanisms, find the right candidates for clinical studies, stratify patients with different risks, predict patient outcomes and drug response and monitor treatment progress using a tissue-agnostic approach. As a global leader in medical imaging analysis and processing, our best-in-class software medical devices and solutions extract objective and highly accurate information versus traditional methods, using the latest AI technology. We have advanced image harmonization techniques generating a standardized image quality that minimizes variability across equipment manufacturers and acquisition protocols. Quibim has access to large scale databases and can analyze any image modality and any tissue from thousands of consecutive patients. *Please note that we do not analyze pathological images.

Gran Capità, 6 08970 Sant Joan Despí, Barcelona, SpainReig Jofré provides manufacturing services and out-licensing dossiers of specialized products.

Julián Camarillo, 35 Madrid, 28037 SpainRovi Contract Manufacturing (RoviCM) offers contract manufacturing services including aseptic filling, terminal sterilization, and safety device assembly.

Madrid, Community of Madrid SpainRovi Contract Manufacturing (RoviCM) offers contract manufacturing services including aseptic filling, terminal sterilization, and safety device assembly.

Avda. de la Innovación 1 Armilla, Granada 18100 SpainRekom Biotech specializes in the production of recombinant antigens as biomarkers of microorganisms and support genomic design and process development for purification of native and recombinant proteins.

Hospital General Universitario Gregorio Maranon de MadridThe HIV Biobank was created in 2004 as a bank of biological samples, whose mission is to contribute to the advancement of scientific knowledge in HIV infection. To achieve this goal, HIV Biobank samples performs a regulated storage conditions to ensure their usefulness and future investigations that may arise as you advance knowledge of this disease.

Calle Nueva 8, local 10 31192 Mutilva- Navarra Mutilva, Navarra, 31192 SpainRECOMBINA is a biotechnological company that offers genetic engineering and molecular microbiology services for the construction of novel recombinant microorganisms with the aim of improving production processes and generating innovative biotechnological products.

226, 1° Planta, 08901 L'Hospitalet de Llobregat, BarcelonaRandox Laboratories, through its business units, offer diagnostic services, life science reagents, biomarker testing services, antibody/drug assay development, and toxicology services.

Barcelona, CT SpainSTE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

Avda. Universitat Autònoma, 13STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

Avda. Ramón y Cajal, 103STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

c/ Afueras, s/n. Sant Martí Sesgueioles Barcelona, SPAIN 08282

Ronda G. Marconi, 6 - 46980 Paterna, Valencia, SpainSistemas Genómicos provides molecular biology, bioinformatics, genomic and sequencing services.

Pol. Industrial Sant Antoni P6 N2 Barcelona, 08620 SpainIn a complex field with increasingly strict demand, Siemsgluss Ibérica has specialized in services which combine regulatory support with strategic planning, by approaching the distribution of the chemical products sector in a new way.

Polígono Aranguren, 9, Apartado de Correos 171 E-20180 OIARTZUN, Gipuzkoa, (Spain).April 2004, Sensia spun-off from the technologies developed at the Biosensor Group within the National Microelectronics Centre (CNM) of the Spanish National Research Council (CSIC). Concluding research results and availability of biosensing systems already working at lab level originated the proposal of bringing a small portable device into commercialization. MONDRAGON Componentes entered Sensia’s sharehold in fall 2007, and the MONDRAGON Componentes Division took total control of the Company in 2012. Presently, SENSIA launches a new SPR (Surface Plasmon Resonance) device called Indicator, for laboratory use, bringing rupture into conventional SPR technologies, with a versatile machine enabling both gold biosensing and graphene biosensing, reaching unattained sensitivities in the SPR world..

c/o Fagor Electrónica, S.Coop. San Andrés, s/n E-20500 MONDRAGON, Gipuzkoa, (Spain).April 2004, Sensia spun-off from the technologies developed at the Biosensor Group within the National Microelectronics Centre (CNM) of the Spanish National Research Council (CSIC). Concluding research results and availability of biosensing systems already working at lab level originated the proposal of bringing a small portable device into commercialization. MONDRAGON Componentes entered Sensia’s sharehold in fall 2007, and the MONDRAGON Componentes Division took total control of the Company in 2012. Presently, SENSIA launches a new SPR (Surface Plasmon Resonance) device called Indicator, for laboratory use, bringing rupture into conventional SPR technologies, with a versatile machine enabling both gold biosensing and graphene biosensing, reaching unattained sensitivities in the SPR world..

Polígono Industrial Los Palillos, 6 - Nº 33 41500 - Alcalá de Guadaira (Sevilla, España)SPHERAGRO es una empresa privada española creada en 2012 dentro del sector de la experimentación agrícola. Con autorización ministerial EOR Nº 79/13, trabajamos de forma independiente, proporcionando datos científicos válidos para propósitos de registro y desarrollo en los distintos campos de la industria agroalimentaria que nos son aplicables. Realizamos todo tipo de ensayos, tanto biológicos como Oficialmente Reconocidos con la excelencia y profesionalidad avalada por nuestros muchos años de experiencia y formación.

Salobreña, AL, 18680 SpainSICOP is a service company that develops its activity in the area of Research and Development of plant protect products, included Botanical and Strengtheners and Biological Control Organism. Our head office is located in Salobreña (Granada), a strategic enclave of vegetables production in intensive-farming in the Mediterranean coast. We operate in the main farming areas all over the Spanish geography and also abroad. SICOP puts at the disposal of the customer the complete implication of all people in the company, with rigour and quality assurance in all our offered services. Our work is well-known and recognized by the main national and international companies in the areas of plant protect products, seeds and fertilizers, placing us as one of the most consolidate service company in these areas.

Leioa, PV SpainGeneral Research Services (SGIker), created by the University of the Basque Country / Euskal Herriko Unibertsitatea, offers its facilities to provide support in genomics, proteomics, microscopy, animal studies.

C/ Melchor Fernández Almagro, 3, E-28029 MadridThe CNIO Biobank is a cross-service platform for CNIO researchers and the general research community oriented towards the promotion of biomedical research in cancer and related diseases.

Barcelona, CT SpainSequentia Biotech is a leading bioinformatics company that offers state of the art NGS data analysis and interpretation, enabling a deeper exploration of omics information and translating it into actionable insights.

Bellaterra – Cerdanyola del Vallès 08193 Barcelona SpainSequentia Biotech is a leading bioinformatics company that offers state of the art NGS data analysis and interpretation, enabling a deeper exploration of omics information and translating it into actionable insights.

Autovia Castelldefels C-31 km 190.50 El Prat del Llobregat - Barcelona, Spain, 08820 SpainSPECIPIG, is a pioneer Breeding and Biomedical Research Centre focused on the pig model. We breed miniature pigs and run in-vivo pig model studies for: - Medical device, tissue regeneration and new materials development: to test prototypes, to establish efficacy, to determine biocompatibility, to improve product knowledge, to minimize risk in the development, to convince the market with scientific evidence, and to attract investment to further develop the project. - Pharma preclinical development: to run efficacy, toxicology, pharmacokinetic, tolerance and proof of concept studies. We are GLP certified and have fully equipped surgery rooms and housing facilities to be able to fully cover the needs of any trial. We are experts on the pig model, training the pigs to cope with the trial requirements with the least stress and securing the best welfare.

Kabi 612, Parque Tecnológico de Bizkaia - c/ Astondo Bidea Derio, Bizkaia, 48160 SpainStemTek is a global biopharmaceutical company with a clear stem cell focused research services portfolio in drug development for cancer treatment. Our interest is not just be the first line research services provider for the pharmaceutical industry but to go beyond current barriers in drug screening to overcome unmet needs for cancer treatment for the benefit of society as a whole. Recent discoveries in cancer research and stem cells are allowing unprecedented breakthroughs in anti-cancer treatment approaches, creating new business opportunities in drug discovery. StemTek uses state of the art technology and world class science to contribute to a novel generation of anti-cancer drugs. StemTek is dedicated to accelerating drug discovery in cancer using cutting edge technology, world-class science and a stem cell centric point of view for cancer therapy. Why Stemtek? Drug screening against cancer stem cells based on 3D cell culture systems, such as tumor spheroid characterization, allows stronger, more efficient an reliable drug screening than conventional 2D based monolayer culture systems currently used by pharmaceutical industry. StemTek has developed a portfolio added-value research services that allows customers to profile their pipeline of compounds for their effect on cancer stem cell populations, using 3D culture models (tumor spheroids) besides a variety of gold-standard approaches for cancer stem cell identification, benefiting from the extense experience of the scientific team at StemTek in cancer stem cell research.

BIC Bizkaia, Astondo Bidea s/n, Derio, 48160, SpainStemTek is a global biopharmaceutical company with a clear stem cell focused research services portfolio in drug development for cancer treatment. Our interest is not just be the first line research services provider for the pharmaceutical industry but to go beyond current barriers in drug screening to overcome unmet needs for cancer treatment for the benefit of society as a whole. Recent discoveries in cancer research and stem cells are allowing unprecedented breakthroughs in anti-cancer treatment approaches, creating new business opportunities in drug discovery. StemTek uses state of the art technology and world class science to contribute to a novel generation of anti-cancer drugs. StemTek is dedicated to accelerating drug discovery in cancer using cutting edge technology, world-class science and a stem cell centric point of view for cancer therapy. Why Stemtek? Drug screening against cancer stem cells based on 3D cell culture systems, such as tumor spheroid characterization, allows stronger, more efficient an reliable drug screening than conventional 2D based monolayer culture systems currently used by pharmaceutical industry. StemTek has developed a portfolio added-value research services that allows customers to profile their pipeline of compounds for their effect on cancer stem cell populations, using 3D culture models (tumor spheroids) besides a variety of gold-standard approaches for cancer stem cell identification, benefiting from the extense experience of the scientific team at StemTek in cancer stem cell research.

Parc Cientific de Barcelona c/ Baldiri Reixac 10-12 Barcelona, Barcelona, 08028 SpainSolitek combines an excellent understanding of the diversity of the solid form landscape exhibited by APIs with the experience and the practical know-how to add value to new chemical entities, thus increasing their chances of making it all the way to the market. We offer stage appropriate development for each programme, focusing on problem solving to reduce the risk of failure during later development stages and / or to maximize the returns from potential in-licensing partners.

C/Faraday, nº7, Lab. 2.05 España Madrid, Madrid, 28049 SpainSynthelia Organics SL is a CRO focused on five pillars: - MedChem servicies - Development and optimization of synthetic routes of advanced intermediate / large-scale intermediates to speed up drug development in medical chemistry. - GMP like synthesis of compounds for preclinical assays. - Flow chemistry services ranging from the development of small-scale routes to the construction of production equipment. - Synthesis of gold nanoparticles functionalized with RNA.

Calle Torres Quevedo 15 Alcobendas, Madrid, 28108 SpainSynthelia Organics SL is a CRO focused on five pillars: - MedChem servicies - Development and optimization of synthetic routes of advanced intermediate / large-scale intermediates to speed up drug development in medical chemistry. - GMP like synthesis of compounds for preclinical assays. - Flow chemistry services ranging from the development of small-scale routes to the construction of production equipment. - Synthesis of gold nanoparticles functionalized with RNA.

Parque Científico y Tecnológico de Bizkaia Idiazabal Bidea, 501B Zamudio/Vasque Country, Bizkaia, 48170 SpainCDMO and CRO of linear synthetic DNA for use as IVT template mRNA manufacturing, AAV, NVV & Gene Editing, saRNA We increase the functionality of the DNA and customized to the Gene therapy use case. Delivery time THREE WEEKS

Parque Tecnológico Rabanales 21 Cordoba, Cordoba, 14014 Spain

CEIN Square, 5 office A4 Noain, Navarra, 31110 SpainThe Zebrafish Lab is a Contract Research Organization (CRO) specialized in developing and marketing novel in vivo zebrafish-based assays increasing the compound success rate and decreasing the failures ratio due to adverse side effects, throughout the drug research and development process. We provide innovative services for industries from different sectors: Pharmaceuticals, Biotechnology, Environment, Natural Products, Nutraceuticals, Industrial Chemicals, Agrochemicals, Food additives, Cosmeceuticals and Skin care products.

Santibáñez de Béjar 3Telstar Life Science Solutions designs, manufactures, sell and support of high technology equipment solutions for the pharmaceutical, biotech and related industries

Av/ Font i Sagué, 55Telstar Life Science Solutions designs, manufactures, sell and support of high technology equipment solutions for the pharmaceutical, biotech and related industries

Terrassa, CT SpainTelstar Life Science Solutions designs, manufactures, sell and support of high technology equipment solutions for the pharmaceutical, biotech and related industries

Parque Científico y Tecnológico Bizkaia Edificio BIC 612 Derio, Bizkaia, 48160 Spain

Pol. Ind. Les Valletes C/ Artes Gráficas 44 46192 Monserrat Valencia - ESPAÑAWHO WE ARE: Trialcamp is an international contract research organization (CRO) and offers a comprehensive range of research and product development services. We provide services to the pharmaceutical, crop protection and chemical industry all around the world by conducting developmental research to support their global regulatory submissions. OUR VALUES 1.- We are innovative: We rapidly adapt the needs of our clients to the new and changing requisites of regulatory authorities by developing new tailor-made techniques. 2.- Quality Assurance: We are constantly working to improve conditions relating to the quality of our work , by controlling each step of the process, investing in technology and providing our team with the most effective training, tools and professional development to ensure the highest standard of quality and service. 3.- Our prices: Our pricing policy is well known to be non-changing policy. Our quotations are very competitive and no additional cost is incurred once the quotation is accepted. 4.- We give solutions: Trialcamp is aware of the fact that companies have no time to think about any concern. Trialcamp has an in-depth experience in solving problems of their clients and setting up rapidly trials in extreme conditions, giving them the expected results.

583 Gran Via de les Corts Catalanes Barcelona, CT , 08011 Spaintebubio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

Barcelona, CT SpainUAB is internationally renowned for its quality and innovation in research.

Avenida de Madrid, 11Univ. of Granada Tissue Engineering Research Group focuses on histology research for therapeutic areas.

C/ Faraday 7 Madrid, Madrid, 28049 SpainServices provider in Genomics

Av. Camilo José Cela, 7 Ciudad Real, 13005 SpainFrom modest beginnings three decades ago, the University of Castilla-La Mancha ( UCLM ) has become a reference for higher education in the Castilian- La Mancha community. With a campus in Albacete, Ciudad Real, Cuenca and Toledo and university headquarters in Talavera de la Reina and Almadén, it is a modern and competitive institution with about 30,000 students, 2,270 teachers and researchers and 1,059 professionals in administration and services. Our mission goes beyond preparation for the exercise of professional activities. We not only create and transmit science, technology and culture, but we commit ourselves to economic development and we have in excellence the reference for teaching, research and transfer. In our way we are guided by solidarity, sustainability, efficiency, merit, capacity, transparency and the promotion of equality. The university community is diverse and united, which constitutes the most suitable scenario for academic exploration and growth. The UCLM is a smart choice for those who outline their future, for those looking to improve their training throughout life and for foreign students pursuing academic, vital or language enrichment bet. Also for companies, which find in our research offer a wide range to optimize your chances in terms of R & D + I . What makes a university great is its people. Therefore, we value and appreciate your interest and your enthusiasm, whether you are a pre-university, student, teacher, researcher, administration and services worker, graduate, parent, mother, neighbor or visitor. It does not matter if one is a Nobel Prize or enrolled in first year. We also invite you to seek answers to fundamental and urgent questions facing society.

Av. Blasco Ibáñez, 13 Valencia, 46010 SpainUniversity of Valencia focuses on research in various areas.

Av de los Naranjos Valencia, 46022 SpainThe Institute of Chemical Technology (ITQ) is a joint research center created in 1990 by the Universitat Politècnica de València (UPV) and the Higher Council for Scientific Research (CSIC) based at the UPV Campus. ITQ is a reference center in the field of catalysis, new materials (especially zeolites) and photochemistry. Thanks to its excellent level of fundamental and already oriented multidisciplinary research, ITQ has the capacity to act at interfaces between disciplines, thus having a wide flexibility and rapid adaptation to new lines and challenges. It has specialized human resources as well as state-of-the-art facilities to develop research in the field of chemical and new materials technologies. It is made up of more than two hundred professionals from around the world divided into: Research Professors, Researchers and Scientific Scientists of the CSIC, Professors and Lecturers of the UPV, Guest Professors, senior technicians, administrative and support staff, as well as scholarship holders and contractors Pre and post doctoral. The lines of work develop them through projects of National Plan, European, regional and financed with own funds. In addition, ITQ derives part of its funding through R & D contracts with multinational companies around the world. Finally ITQ also finances part of its research thanks to the revenues from the exploitation of patents developed in the Institute and licensed to companies that market them. The ITQ also offers a suitable environment for the training of technical and research personnel, in the preparation of theses, end-of-course projects and postdoctoral stays.

Rectorate Building Patio of Schools 1 Salamanca, 37008 SpainThe University of Salamanca, founded in 1218, is a medium-sized university with more than 30,000 students, with a great capacity for attraction as it is the second university in the country where more students from outside the university district study.

Avinguda Alcalde Rovira Roure Lleida, CT, 25198 SpainMajor research areas of The Weed Research Group include: Integrated weed management Biodiversity Weed biology and ecology Herbicide trials for registration (EOR Nº 75/12)

Sant Vicent del Raspeig, Valencian Community, 03690 SpainThe Genomics and Proteomics Unit is focused on the area of basic research in Biology and Molecular Biochemistry.

Barcelona, CT SpainThe Systems Pharmacology Group was established in September 2003. It is part of the Research Programme on Biomedical Informatics (GRIB), a joint research programme of IMIM-Hospital del Mar Research Institute (IMIM), a research institute appointed to the University Pompeu Fabra (UPF).

Gran Via de les Corts Catalanes 585 Barcelona, 08007 SpainThe University of Barcelona (UB) is Spain’s leading research university, publishing more research than any other Spanish institution with the exception of the Spanish National Research Council (CSIC) (Third European Report on Science and Technology Indicators). The guidelines for research policy are drawn up by the Office of the Vice-Rector for Research. Research activities are managed by the UB office Research Management (OGR), which is in charge of national research programs, the UB office International Research Projects (OPIR), which is responsible for European projects, and the Bosch i Gimpera Foundation (FBG), which oversees knowledge transfer and relations with the business sector. The Science and Technology Centres (CCiTUB) are a group of UB centres that support research both in the university and in other public and private institutions.

1, 33003 Oviedo, SpainUniversity of Oviedo provides cytometry, elemental analysis, and protein services.

Jordi Girona 1 Barcelona, Barcelona, 08034 SpainTechnological university

EEBE, Dept of Physics Eduard Maristany Barcelona, Barcelona, 08019 SpainTechnological university

Jordi Girona 1 Barcelona, Barcelona, 08034 SpainTechnological university

C/ Mallorca 262, 3rd floor Barcelona 08008 SpainUquifa offers custom synthesis, manufacturing of APIs and intermediates.

Polígon Industrial Molí de les Planes C/ Font de Bocs S/N, C-35, KM 57 08470 Sant Celoni (Barcelona) SpainUquifa offers custom synthesis, manufacturing of APIs and intermediates.

Polígono industrial el Pla Avda Puigcerda, 9 C-17, Km 17.4 08185 Lliçà de Vall (Barcelona) SpainUquifa offers custom synthesis, manufacturing of APIs and intermediates.

119 Passeig de la Vall d'Hebron, Barcelona, CT 08035, ESThe High Technology Unit provides state-of-the-art facilities along with scientific and technical expertise to assist in experimental design and data analysis. This Unit is intended to provide researchers with an integrated service. Our staff will help you with your experimental design, grant writing, implementation, assay development and data analysis and interpretation. We also offer a variety of advanced equipment under self-service for advanced users. How are we different from others? Our added value is that we accompany and guide researchers through the whole experimental process and across as many disciplines as necessary, entering a virtuous loop that can be fed back as many times as required.

Pg. Vall d’Hebron, 119-129 Barcelona, 08035 SpainThe High Technology Unit provides state-of-the-art facilities along with scientific and technical expertise to assist in experimental design and data analysis. This Unit is intended to provide researchers with an integrated service. Our staff will help you with your experimental design, grant writing, implementation, assay development and data analysis and interpretation. We also offer a variety of advanced equipment under self-service for advanced users. How are we different from others? Our added value is that we accompany and guide researchers through the whole experimental process and across as many disciplines as necessary, entering a virtuous loop that can be fed back as many times as required.

Hospital Universitari Vall d'Hebron Passeig de la Vall d'Hebron, 119-129 08035 SpainMission The HUVH Biobank is a platform that works to obtain, store, manage and distribute large collections of biological samples of high interest in Vall d'Hebron conceived for biomedical research purposes, and that it is organized as a technical unit with quality, order and destination criteria; that guarantees the rights of donors and enables the work of researchers to whom it also offers technical advice on research projects that collect human samples. Vision We want to be a top quality service in the activities that we develop, being a national reference of cooperation by harmonizing procedures, promoting institutional integration and by providing samples and associated data as a service within the framework of Law 14/2007 Biomedical Research; and at the same time providing a strong commitment with the ethical principles associated with our activity as a human biological research biorepository. Values The Biobank is a structure committed to ethics which respects the individuality of the donor; at the same time the Biobank has a vocation of service characterized by quality, transparency, collaboration and permeability to the biomedical research community.

119 Passeig de la Vall d'Hebron, Barcelona, CT 08035, ESThe Statistics and Bioinformatics Unit (UEB) was created in 2008 in order to promote the use and development of modern statistical and bioinformatics resources on research performed in its environment. Nowadays, the Statistics and Bioinformatics Unit includes the former Support Unit in Methodology for Biomedical Research (USMIB) and, as part of the Scientific and Technical Support Area of the Vall d'Hebron Research Institute, has the mission to provide expert advice, services and training for clinical and biomedical research. The main objectives of the UEB are: To provide statistical, methodological and bioinformatics support for clinical and biomedical research, mainly in our center but also to the rest of the community. To contribute to training in statistics and bioinformatics for clinical and biomedical research, by conducting its own courses and participating in formal training in the VHIR's area. To carry out innovation and development activities in the field of statistics and bioinformatics, particularly in anything that could revert in an improvement of the procedures and services provided by the Unit.

Pg. Vall d’Hebron, 119-129 Barcelona, 08035 SpainThe Statistics and Bioinformatics Unit (UEB) was created in 2008 in order to promote the use and development of modern statistical and bioinformatics resources on research performed in its environment. Nowadays, the Statistics and Bioinformatics Unit includes the former Support Unit in Methodology for Biomedical Research (USMIB) and, as part of the Scientific and Technical Support Area of the Vall d'Hebron Research Institute, has the mission to provide expert advice, services and training for clinical and biomedical research. The main objectives of the UEB are: To provide statistical, methodological and bioinformatics support for clinical and biomedical research, mainly in our center but also to the rest of the community. To contribute to training in statistics and bioinformatics for clinical and biomedical research, by conducting its own courses and participating in formal training in the VHIR's area. To carry out innovation and development activities in the field of statistics and bioinformatics, particularly in anything that could revert in an improvement of the procedures and services provided by the Unit.

13th Floor. Mother and Child Area HUVH Passeig de la Vall d'Hebron, 119-129 Barcelona, 08035 SpainThe Support Unit for Clinical Research is located on the 13th floor of the Mother and Child Area, at the Vall d’Hebron University Hospital, and it is comprised of two areas, coordinated centrally: The Healthcare Area: provides healthcare support to the development of clinical research within Vall d’Hebron, and offers medical offices to the users. The Management Area: its main function is to provide support in matters of ethics, methodology, regulations and management in the realization of clinical research within Vall d’Hebron, and is part of the SCReN Platform (Spanish Clinical Research Network) from the Instituto de Salud Carlos III.

4-12-15 Carrer de Baldiri Reixac Barcelona, CT, 08028 SpainVan Loon Chemical Innovations (VLCI) provides valuable and innovative R&D services to the formulation industry, on a project-by-project basis. By combining knowledge, experience and High Throughput, we boost development processes and improve properties of polymers, coatings, personal & beauty care, household and pharmaceutical products. VLCI has its own proven concept: Various products introduced onto the market up to 5 times faster, allowing our customers to save costs on R&D projects.

Pol.Ind. Dos de Octubre, Plaza Domínguez Ortiz Santa Fé, Granada 1 SpainVircell specializes in the development and production of ready-to-use reagents for the diagnosis of infectious disease in humans. Products include ELISA kits, cell lines, reagents, and antigens.

PO Box 33300 Barcelona, 08080 SpainVitoTag Biosciences offers peptide synthesis, polyclonal antibody and cell based assay services.

Barcelona, CT SpainVitoTag Biosciences offers peptide synthesis, polyclonal antibody and cell based assay services.

Mediterrània Building, ground floor Passeig de la Vall d'Hebron, 119-129 Barcelona, 08035 SpainResearch and teaching related to the use of laboratory animals is focused on the animal house of the Institut de Recerca de l'Hospital Universitari Vall d’Hebron. Located at Edifici Mediterrània, it occupies a built area of 745 m2 and a useful area 683 m2 in a single floor. Animal house obey the legislation in force and it is registered at the Departament de Medi Ambient i Habitatge with register number B9900062. Facilities are divided in two areas: Rodent Area with an standard clean area, a passive quarantine, a barrier area to accommodate immunodeficient mice, 6 manipulation rooms and the Molecular Imaging Platform; as well as the Large Animals Area with space enough to accommodate rabbits, pigs and sheep with complete experimental operating rooms to carry out teaching and experimental surgery projects. This animal house has a Committee composed by different researchers of the Institut who advice in scientific issues related with the animal house. On the other hand, the institute has an Ethical Committee of Animal Experimentation (CEEA). The animal house objectives are: Providing accommodation for experimental animals maintenance, care and welfare. Periodic health control to maintain the animals in proper health and then obtain reproducible and reliable results. Satisfying user needs by giving them the advice and the equipment to carry out the investigation with experimental animals. Ensuring compliance with all legal and ethical standards related with animal used for experimentation and other scientific purposes.

EDIFICIO TANDEM Miramon Pasealekua 170-1st floor Donostia, Gipuzkoa, 20014 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

EDIFICIO TANDEM Paseo Miramon 170-1st floor Donostia, 20014 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

EDIFICIO TANDEM Paseo Miramon 170-1st floor Donostia-san Sebastian, 20014 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

Paseo Miramon 170-1st floor Donostia-san Sebastian, 20014 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

Paseo Miramon 170 Donostia-san Sebastian, 20014 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

81 Mikeletegi Pasealekua Donostia, PV, 20009 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

Paseo Mikeletegui. Nº 81 San Sebastian, Guipuzcoa, 20009 SpainVIVEbiotech is a GMP Contract Development Manufacturing Organization (CDMO) specialized in Lentiviral vectors. VIVEbiotech offers an integral service, from early stages, up to the manufacture for preclinical toxicology, clinical and commercial phases. Moreover, VIVEbiotech has developed its own technology, LENTISOMA, that is a non-integrative episomal replicative lentiviral vector.

2 Calle de Santiago Grisolía Tres Cantos, Comunidad de Madrid, 28760 SpainVivia offers pharmacological profiling and CDx/biomarker discovery services in patient samples to provide key information for drug development. We partner with drug developers throughout every stage of drug research and development with our proprietary PharmaFlow Technology Platform, from target discovery to biomarker discovery and companion diagnostic in clinical trials. We are working with more than 20 pharmaceutical and biotechnology companies worlwide to enable precision medicine driven therapies. PharmaFlow PM is a precision medicine platform to personalize the treatment of patients suffering Hematological Malignances. PharmaFlow PM generates clinically predictive data: patients predicted sensitive in 1st line show 92% CR at induction and 75% OS at 3-years* Vivia enables early identification of drug resistant clones to unleash targeted molecular biomarker discovery programs, uncovering the molecular basis of resistance of your drug. Vivia offers unique, state of the art, native environment immune-oncology and microenvironment assays. PharmaFlow PM CDx can deliver over 90% compelete remisión (CR) on your drug’s clinical trial. 92% CR 92% 75% OS 75% * Results from observational clinical trial with Pethema in Spain in 123 AML patients treated with first line Cytarabine and Idarubicin. Publication ready for early issuance. Vivia offers to its partners proprietary Native Environment Assays in patient’s whole bone marrow, assessing the drug activity in the native tumor microenvironment: Assays include state of the art immune-oncology (IO drugs, CAR-T), and microenvironment assays (BCR inhibtiors) Key deliveries of PharmaFlow PM for your drug development: Direct impact in ROI over 90% CR in clinical trials as CDx Identification of early molecular biomarkers of efficacy/resistance Better understanding of MOA & interpatient variability of response Best combos to incrase market share & overcome resistance in clinical trials Market positioning vs. SOC and competitive drugs Vivia can also enable fast deployment of Investigator Sponsored Trials with its European KOL network, where PharmaFlow PM would be used as CDx.

Calle de Santiago Grisolia 2 Tres Cantos, Madrid, 28760 SpainVivia offers pharmacological profiling and CDx/biomarker discovery services in patient samples to provide key information for drug development. We partner with drug developers throughout every stage of drug research and development with our proprietary PharmaFlow Technology Platform, from target discovery to biomarker discovery and companion diagnostic in clinical trials. We are working with more than 20 pharmaceutical and biotechnology companies worlwide to enable precision medicine driven therapies. PharmaFlow PM is a precision medicine platform to personalize the treatment of patients suffering Hematological Malignances. PharmaFlow PM generates clinically predictive data: patients predicted sensitive in 1st line show 92% CR at induction and 75% OS at 3-years* Vivia enables early identification of drug resistant clones to unleash targeted molecular biomarker discovery programs, uncovering the molecular basis of resistance of your drug. Vivia offers unique, state of the art, native environment immune-oncology and microenvironment assays. PharmaFlow PM CDx can deliver over 90% compelete remisión (CR) on your drug’s clinical trial. 92% CR 92% 75% OS 75% * Results from observational clinical trial with Pethema in Spain in 123 AML patients treated with first line Cytarabine and Idarubicin. Publication ready for early issuance. Vivia offers to its partners proprietary Native Environment Assays in patient’s whole bone marrow, assessing the drug activity in the native tumor microenvironment: Assays include state of the art immune-oncology (IO drugs, CAR-T), and microenvironment assays (BCR inhibtiors) Key deliveries of PharmaFlow PM for your drug development: Direct impact in ROI over 90% CR in clinical trials as CDx Identification of early molecular biomarkers of efficacy/resistance Better understanding of MOA & interpatient variability of response Best combos to incrase market share & overcome resistance in clinical trials Market positioning vs. SOC and competitive drugs Vivia can also enable fast deployment of Investigator Sponsored Trials with its European KOL network, where PharmaFlow PM would be used as CDx.

Calle Córcega 303, 5° 08008 Barcelona SpainWacker offers contract manufacturing, biologic analysis, and quality control/assurance services.

Avda Carlos III, 36 1 Derecha Pamplona 31003 Navarra SpainActivery offers thermal analysis services.

C/ Portugal 33-35 08290 Cerdanyola del Vallès BarcelonaActivery offers thermal analysis services.

Barcelona, CT SpainAdvancell offers animal models, drug delivery, BA/BE studies, species compariation, and AMES testing.

Parc Científic de Barcelona - Baldiri i Reixac 10-12 Barcelona 08028 SpainAdvancell offers animal models, drug delivery, BA/BE studies, species compariation, and AMES testing.

Barcelona, CT SpainABC Farma Internacional specializes in cosmetic, transdermic and hydrogel patches.

Villamayor, CL, 37185 SpainApointech offers compound evaluation, pharmacological screening, pharmacogenomics, cellular analysis, and in vivo/vitro xenograft studies.

Laboratorio 4 CIALE - C/Río Duero 12 Villamayor, Salamanca 37185 SpainApointech offers compound evaluation, pharmacological screening, pharmacogenomics, cellular analysis, and in vivo/vitro xenograft studies.

Paseo de la Castellana 141 Edificio Cuzco IV Planta 20 28046 Madrid SpainAccovion provides regulatory consulting, medical services, clinical management, and pharmacovigilance.

Urb. El Eucaliptal. Cordialidad, 9. 41500 Alcalá de Guadaira. Seville. SPAINAgricultura y Ensayo is an agricultural services company dedicated mainly to activities related to the Research and Development (R+D) of agrochemicals products. Established in 1997, AYE is manned by highly qualified personnel with broad experience. AYE operates all over the Spanish and Portuguese geography. The head office is located in the South of Spain (Alcalá de Guadaira, Sevilla); there are some other secondary offices spread around the South (Almería) and the North (Navarra, País Vasco and Galicia) and our branch in Central Region of Portugal (Almeirim).

Elexalde Derio, PV SpainAbyntek Biopharma provides comprehensive and personalized service in the supply of antibodies.

Parque Tecnológico de Bizkaia Ed. 801B-2ª planta 48160 Derio Vizcaya (Spain)Abyntek Biopharma provides comprehensive and personalized service in the supply of antibodies.

Parque Tecnologico Tecnobahia Puerto de Santa Maria, SpainAgroaxis sprouted as an innovating idea from the founder member, who owns a deep market insight thanks to more than 35 years experience in the biopharmaceutical field. The company was established in 2010 and just three years, the company is nominated as the ten top in the word as biosimilar`s with the support of the European Union, Public Administration, through founding aimed at the development of R&D SMEsCurrently, it also boasts its own Research Center, 3200 m2, located in the Parque Tecnologico Tecnobahia Puerto de Santa Maria (Spain). Additionally, it is working in laboratory situated in El Puerto de Santa María (Spain). Agroaxis is currently the only one company in Spain that is integrated from bench to production and commercialization of biosimilars, among other therapeutic proteins, through a plant based protein expression system. The vision of Agroaxis is to become the reference in the pharmaceutical sector regarding the production and commercialization of nutraceutics and CMO services. It aims at being a leading company in its area, both on the national and international scale, thanks to its commitment with the high quality standards of its products and services. The mission of the company is the research, development, production and distribution of pharmaceutic and biopharmaceutic products and services. It has specialized in the production of therapeutic proteins. To this aim, Agroaxis has developed highly competitive processes of molecular biology that are based on expression systems, industrial scale plant culture, extraction and purification of proteins., all this using plant biofactories. The values that integrate the Agroaxis culture are focused on directing the whole company to address the client´s requirements: leadership, integrity, flexibility and efficiency. Agroaxis´ staff is integrated by 8 people. 90% of them are exclusively devoted to R&D&I and everyone were hired through the INNCORPORA TU and INNCORPORA FPGS, programs, which are aimed at the recruitment of qualified staff.

Madrid, Community of Madrid SpainAgrenvec supplies and produces recombinant proteins and monoclonal/polyclonal antibodies.

C/Santiago Grisolia 2, D132 Tres Cantos, Madrid PCM 28760 SpainAgrenvec supplies and produces recombinant proteins and monoclonal/polyclonal antibodies.

Ctra. Ronda 11 , bajo 04004 AlmeríaLEADERS IN VOLUME AND SALES In the last 5 years we have maintained a sustained growth of over 20% based on the continued expansion of our services and in a consistent geographic expansion. During the last campaign we have made up to 20 different types of audit and Certification, to 3,140 customers in more than 25 different products covering more than 410,000 hectares of crop. Agrifood LEADERS TRUST US We are proud to count among our customers with the best food producers on the national scene. Leaders for size, specialization and what is more important, leaders for their commitment to quality. We are near you We have seven branch offices across the major growing areas nationwide because we want to be near you and learn more about the reality of your business. A TEAM OF EXPERTS More than 50 experts in agricultural and industrial engineering. Our ongoing training program allows us to remain at the forefront of knowledge in the area and food audit certification. BUILDING CERTIFICATION Only from understanding we can help in the continuous process of quality improvement. We are always willing to listen to enhance our certification processes. WITH BEST MARKET CONDITIONS We invite you to get certified with us. You can experience the agility of our system with the best market rates and with full transparency. All this with the guarantee that your certification is always accredited by ENAC (National Accreditation).

14 Calle la Palma 14-2 Córdoba, AL, 14002 SpainRepetitive tasks in your workflow can take precious time necessary for breakthrough ideas to happen. Wimasis offers image analysis services designed to improve the results of your most time-consuming and challenging manual assay analyses.

La Palma 14-2 Córdoba, 14002 SpainRepetitive tasks in your workflow can take precious time necessary for breakthrough ideas to happen. Wimasis offers image analysis services designed to improve the results of your most time-consuming and challenging manual assay analyses.

Po Marshes. Calafates Street No. 5. Santona, Cantabria 39740 SpainZF Biotox developed and offers its proprietary in vitro technology to provide frozen cells in microplates ready-to-use in cell-based assays.

Santoña, Cantabria SpainZF Biotox developed and offers its proprietary in vitro technology to provide frozen cells in microplates ready-to-use in cell-based assays.

Calle Gran Via 62, 4ºIzq – 28013 MadridZurko Research , since 2005, is offering to its clients a high-level technical support in the development of biotechnological solutions in the areas of health, food and agriculture and environment. But in the recent years, the company has adapted its strategy development according to the trends of current market needs in the sectors of health and personal care. Strong of its consulting experience in biotechnology, Zurko Research has decided to design and develop new added-value services for the healthcare industry and cosmetics. To this purpose the company has decided to create a specific department called Zurko Cosmetics and services aimed at testing cosmetic ingredients and products. The department consists of experts in pharmacy and cosmetic biotechnology with great experience in trial development both in vitro live.

Ronda de Valdecarrizo 41º B Tres Cantos 28760 SpainZF BioLabs offers genomic, toxicity and safety assay, and bioassay services using zebrafish as an alternative model of study.

Tres Cantos, Community of Madrid, 28760 SpainZF BioLabs offers genomic, toxicity and safety assay, and bioassay services using zebrafish as an alternative model of study.

C/Cerro de la Carrasqueta 63Zeptosens offers protein microarray profiling for biomarker discovery and validation, cell based screening, selectivity profiling and toxicology assessment.

Carrer de Laureà Miró, 408-410 Sant Feliu de Llobregat , Barcelona, 08980 SpainZeClinics is a Contract Research Organisation that provides pre-clinical testing services using the zebrafish model. ZeClinics expertise in CRISPR genome editing allows developing custom zebrafish genetic models to mimic human disease and addressing the biomedical relevance of candidate compounds and genes in vivo. Zebrafish bridges the gap between cell and rodent experimental models, enabling accelerated and cost-effective drug and target discovery. Our services are tailored for Biotech, Pharma, Agrochemical, Food, and Cosmetic companies and are classified in the following platforms: - ZeEfficacy platform: portfolio of ready-to-use zebrafish models of disease for drug discovery and genetic functional studies in central nervous system, ophthalmology, metabolic areas among other. - ZeTox platform: portfolio of in vivo general and organ-specific toxicity testing services for environmental safety and human risk assessment. - ZeGenesis platform: the most up-to-date genetic catalog for highly efficient mutagenesis, transgenesis, and gene expression modulation to generate zebrafish models of human disease. ZeClinics is a CRISPR/Cas9-licensed organization with extensive experience in generating knock-out and transgenic lines.

c/ Marina 25-27 Barcelona, Barcelona, 08005 SpainZeClinics is a Contract Research Organisation that provides pre-clinical testing services using the zebrafish model. ZeClinics expertise in CRISPR genome editing allows developing custom zebrafish genetic models to mimic human disease and addressing the biomedical relevance of candidate compounds and genes in vivo. Zebrafish bridges the gap between cell and rodent experimental models, enabling accelerated and cost-effective drug and target discovery. Our services are tailored for Biotech, Pharma, Agrochemical, Food, and Cosmetic companies and are classified in the following platforms: - ZeEfficacy platform: portfolio of ready-to-use zebrafish models of disease for drug discovery and genetic functional studies in central nervous system, ophthalmology, metabolic areas among other. - ZeTox platform: portfolio of in vivo general and organ-specific toxicity testing services for environmental safety and human risk assessment. - ZeGenesis platform: the most up-to-date genetic catalog for highly efficient mutagenesis, transgenesis, and gene expression modulation to generate zebrafish models of human disease. ZeClinics is a CRISPR/Cas9-licensed organization with extensive experience in generating knock-out and transgenic lines.

Carretera de Can Ruti, Camí de les Escoles, s/n, Edificio IGTP Muntanya, Laboratorio P0-8 Badalona (Barcelona), (Not in US/Canada), 08916 SpainZeClinics is a Contract Research Organisation that provides pre-clinical testing services using the zebrafish model. ZeClinics expertise in CRISPR genome editing allows developing custom zebrafish genetic models to mimic human disease and addressing the biomedical relevance of candidate compounds and genes in vivo. Zebrafish bridges the gap between cell and rodent experimental models, enabling accelerated and cost-effective drug and target discovery. Our services are tailored for Biotech, Pharma, Agrochemical, Food, and Cosmetic companies and are classified in the following platforms: - ZeEfficacy platform: portfolio of ready-to-use zebrafish models of disease for drug discovery and genetic functional studies in central nervous system, ophthalmology, metabolic areas among other. - ZeTox platform: portfolio of in vivo general and organ-specific toxicity testing services for environmental safety and human risk assessment. - ZeGenesis platform: the most up-to-date genetic catalog for highly efficient mutagenesis, transgenesis, and gene expression modulation to generate zebrafish models of human disease. ZeClinics is a CRISPR/Cas9-licensed organization with extensive experience in generating knock-out and transgenic lines.

Roc Boronat 117 floor 2, modules 4-6 Barcelona, 08018 SpainZYMVOL designs, develops and applies molecular modeling software to accelerate enzyme discovery and design.

Louis Proust St. Boecillo Technological Park Boecillo, Valladolid, 47151 Spain53Biologics is a spanish CDMO focused on recombinant protein and plasmid DNA development and manufacturing. We provide services for cell line development, cell banking, analytical methods development/qualification and validation, upstream and downstream development, big scale production (GMP and non-GMP). Our mission is to provide services to different companies, from start-ups to large companies, as well as to other CDMOs, to help their products to reach the market. 53Biologics works in a quick, proactive, flexible, and efficient way, always ensuring very high-quality standards.

Calle Louis Proust Valladolid, Castilla y Leon, 47023 Spain53Biologics is a spanish CDMO focused on recombinant protein and plasmid DNA development and manufacturing. We provide services for cell line development, cell banking, analytical methods development/qualification and validation, upstream and downstream development, big scale production (GMP and non-GMP). Our mission is to provide services to different companies, from start-ups to large companies, as well as to other CDMOs, to help their products to reach the market. 53Biologics works in a quick, proactive, flexible, and efficient way, always ensuring very high-quality standards.

calle San Benito 48 Madrid, Madrid, 28029 Spain3DforScience is a Global Scientific Communications helping pharmaceutical, biotechnology, medical device and healthcare companies to visualize and explain their science. Our mission is to provide illustrative content and visual aids for the medical, health and technology related industries through 3D animations, Virtual Reality and interactive production to enhance the clients’ health and marketing communications. Focused on helping and advising companies in the health and biotechnology sector, allowing them to explain technologies, research or new therapies and transmit them in an innovative and visual way to differentiate themselves from the competition or make more comprehensible our advances to institutions, clients, partners and society.

Avda. Knowledge s/n 18016 Granada, SpainThe Biobank of Andalusia Public Health System (SSPA) is an initiative of the Department of Equality, Health and Social Policy. Figure 1Through a network operation and under a common ethical framework, a single organizational structure and a decentralized activity, Biobank SSPA integrates all blood banks and tissues for therapeutic purposes, the biobank research and any public health space Andalusian dedicated the collection, processing, storage and transfer of human biological samples to researchers.