Nobelova 34 Bratislava , Bratislava , 836 05 SlovakiaBiosynth is an innovative global life sciences reagents, custom synthesis, and manufacturing services company that secures the fragment pharma and diagnostic supply chain. With an unrivaled research product portfolio and end-to-end manufacturing services, Biosynth is science-led and customer-focused on solving problems and delivering key reagents at scale and with quality. Our expertise and capability runs across fine chemicals/small molecules, peptides and key biologics all from one trusted partner. We manufacture and source a vast range of chemical and biochemical products, and take pride in delivering products that others cannot. We provide a full range of products and services to support life science research and development, with more than a million products in our research catalog and many hundreds of complex manufacturing service projects. Our small molecule chemistry specialties include enzyme substrates, carbohydrate and nucleoside chemistry, as well as intermediates, APIs and controlled substances. Customers can partner across the full product life cycle with no need to change suppliers, with manufacturing services from the first idea to the finished product, from route scouting and optimization to GMP or ton-scale production at sites across Europe and Asia. Biosynth’s peptide division, based in the US and Europe, has over 40 years of expertise in assisting pharma and diagnostics customers and specializes in custom peptide synthesis from nmol up to multiKg scale. From peptide discovery and lead optimization, including our own CLIPS™ technology to lock peptides into active conformations, to GMP NCEs and neoantigens to cover all your needs. Biosynth has a synergistic offering of critical biological raw materials, including mono- and polyclonal antibody production and our unique epitope mapping service as a platform to support your antibody development, including patent applications. Biosynth’s enzyme products and solutions are at the forefront of biocatalysis and also include custom enzyme development and production. Through the Biosynth group, we also offer the development of antibodies, antigens, and supply of plasma for in vitro diagnostics. *Biosynth and the Biosynth Group includes the previous and associated brands: Carbosynth, vivitide, New England Peptide, Peptides International, Pepscan, Eucodis Bioscience, Aalto Bio Reagents, Fitzgerald Industries International, Cambridge Research Biochemicals (CRB) & Celares For more information please visit our website: https://www.biosynth.com/

Sulekova 14 811 06 Bratislava- Slovak RepublicChiesi farmaceutici offers drug development, drug discovery, and clinical trials.

Slovenská Ľupča, 976 13 SlovakiaBiotika offers the production of polymyxin B sulfate and quality medicines for human and veterinary applications.

Skolska 88 99109 Slovakia

42 Školská 055 61 Slovakia

Jegorovova 37 974 01 Banská Bystrica SlovakiaGALVEX manufactures human and veterinary medicines in non-sterile dosage forms.

Popradska 80 Kosice, 040 11 SlovakiaDB Biotech is focused on the design and production of high quality rabbit clonal antibodies.

Galvaniho 7/D 821 04 Bratislava, SlovakiaArgint International provides clinical operations, regulatory services, and project management, primarily for eastern european countries.

Nobelova 34 (located in ISTROCHEM area) P.O. BOX 29 836 05 Bratislava SlovakiaTAU-CHEM, Ltd. - development, research and fine chemicals manufacturing company established in 1994 by the partners with extensive experience in organic synthesis and technology The company specializes in the heterocyclic chemistry, as well as in the more conventional fields of organic synthesis The company´s competency in process development and scale up contributes to raise the production innovation. Mission TAU-CHEM principal function is to carry out a successful market-oriented exploitation by bridging the gap between academic research and large scale realization - technology development or industrial up scaling. The TAU-CHEM ´s business model derived from its mission is based on transferring academic scale chemistry (mg) to production quantities (kg) process optimization followed by transfer to full production (tones).

Sklabinska 30 036 80 Martin SlovakiaHBM Pharma specializes in sterile technologies, injectables in ampoules, solid dosage forms and tablets.

Koreničova 1 Bratislava, 811 03 Slovak RepublicThe company’s research and production divisions focus in particular on the synthesis of benzothiazoles, benzimidazoles, furanes, indoles, isocyanates, isothiocyanates, thiophene derivatives, phosphorus compounds, pyridines, and rare sugars capable of providing these synthetic products from a few grams to many kilograms.

Mlynská dolina 1, 84215 Bratislava, 841 04, SlovakiaSYNKOLA, Ltd. was founded on the 1st January 1991 in Bratislava by three partners. They have long-time and international experience in the area of organic substance synthesis and especially in the area of biologically active substances and chemical specialties. They are authors of more than 200 scientific publications and more than 150 patents; many of them have been realized in technical praxis. Nowadays, the organization employs 14 top chemists with Ph.D. qualification, who have graduated post-doctoral and other fellowships at prominent foreign universities and institutes – especially in Switzerland (ETH Zurich), in the USA, France, Canada, Sweden, etc. SYNKOLA is located in Comenius University campus and takes advantages of following analytic equipment GC-MS, LC-MS, 300MHz NMR, FT-IR. Laboratories are equipped with Parr autoclave and all other necessary equipment for each kind of organic synthesis. There are available also equipments with microwave radiation. profile

1 Mlynská dolina 841 04 SlovakiaSYNKOLA, Ltd. was founded on the 1st January 1991 in Bratislava by three partners. They have long-time and international experience in the area of organic substance synthesis and especially in the area of biologically active substances and chemical specialties. They are authors of more than 200 scientific publications and more than 150 patents; many of them have been realized in technical praxis. Nowadays, the organization employs 14 top chemists with Ph.D. qualification, who have graduated post-doctoral and other fellowships at prominent foreign universities and institutes – especially in Switzerland (ETH Zurich), in the USA, France, Canada, Sweden, etc. SYNKOLA is located in Comenius University campus and takes advantages of following analytic equipment GC-MS, LC-MS, 300MHz NMR, FT-IR. Laboratories are equipped with Parr autoclave and all other necessary equipment for each kind of organic synthesis. There are available also equipments with microwave radiation. profile

Modra, SlovakiaHameln provides custom development, biological studies, clinical trials, and GLP services

Dérera 7At PRA Health Sciences, providing innovative solutions for our clients is what we do. But innovation just for the sake of innovation isn’t why we do it. Side-by-side with our clients, we strive to move drug discovery forward, to help them develop life-saving and life- improving drugs. We help change people’s lives for the better every single day. It’s who we are. Innovating to help people is at the heart of our process, but it’s even more than that. It’s also our privilege.

Kirejevská Rimavská Sobota, 979 01 SlovakiaMIKROLAB Ltd., is a private company focused on the provision of food, health, pharmaceuticals, environment and agriculture. The company is accredited to ISO / IEC 17025: 2005 General requirements for the competence of testing and calibration laboratories . It has been on the market since 1993 and provides services for many national and multinational companies across the SR.

Košice SlovakiaDB Biotech is focused on the design and production of high quality rabbit clonal antibodies.

Bratislava, Slovak RepublicGoodwill Research provides clinical trial management, sample quantification, analytical reports, and internal medicine.

Udernicka 5Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

116 Okružná Rimavská Sobota, 979 01 Slovakia

Strecnianská 13, 851 05 Bratislava, SlovakiaNeox is a privately owned full services clinical CRO. We conduct clinical trials for pharmaceutical, biotechnology, medical device companies and other CRO’s throughout Europe and US. Our services are offered for Phase I-IV. DRUG DEVELOPMENT - Medical Writing, Site Contracting, Clinical Monitoring, Project Management, Pharmacovigilance, Regulatory, Medical Monitoring, Outsourcing. MEDICAL DEVICE DEVELOPMENT PHARMACOVIGILANCE & REGULATORY REAL WORLD EVIDENCE/DATA & HEOR DATA MANAGEMENT & BIOSTATISTICS We offer our services as a full service package or individually as a tailored solution to your specific needs. Years of clinical research experience, understanding local requirements and established relationships with investigators ensures that your trial will always be performed in an optimal setting for high patient enrollment. Neox offices: Czechia, California, Germany, Poland, Hungary, Bulgaria, Slovakia, Romania. Neox also operates in: Austria, Belgium, Estonia, France, Finland, Italy, Latvia, Lithuania, Netherlands, Spain, United Kingdom and others.

73 Mlynske NIvy Bratislava, 821 05 Slovakia