14 rue de la beaune Building C, 2nd floor Montreuil, France, 93100 France4Dcell is a French biotechnology company specialising in New Approach Methodologies (NAMs) for drug development. For nearly a decade, our Paris-based team has been developing solutions that make cells behave as if they're in their natural environment: combining expertise in physics, material science, chemistry, biology, and bioengineering. We pioneered the "Organ-in-a-well" concept through three technologies: Micropatterned Plates, SmartSphero Plates, and SmartHeart Plates. These platforms set new industry standards by delivering unprecedented ease of use for high-throughput screening and data collection from physiologically relevant 3D models. Today, over 1,000 labs worldwide use our microphysiological systems across cardiology, immunology, oncology, hepatology, neurology, and beyond, advancing research that bridges the gap between traditional models and human biology.

191 AVENUE ARISTIDE BRIAND CACHAN, 94230 FranceAbbelight offers advanced nanoscopy solutions for precision medicine and cell therapy in oncology

5 Rue Henri Auguste Desbruères Évry, Île-de-France, 91030 FranceWHO ? Abcell-bio is a French biotechnology company which provides a reliable source of human primary cells isolated from perinatal tissues and adequate culture media. WHAT ? Abcell-bio is specialized in production of: • Hematopoietic Cells isolated from cord blood or peripheral blood: CD34+ Hematopoietic Progenitors, MonoNuclear Cells from cord blood (MNC), Peripheral Blood Mononuclear Cells (PBMC) • Endothelial cells isolated from umbilical cord or cord blood: Endothelial Progenitor Cells (EPC), Human Umbilical Vein Endothelial Cells (HUVEC), Human Umbilical Artery Endothelial Cells (HUAEC) • Cell Culture Media: production of cell culture media dedicated to human primary cells HOW ? Abcell-bio has a unique expertise: the company controls the entire process from blood collection in maternity wards to the production of high-quality cells in dedicated laboratory facilities Thanks to its expertise, Abcell-bio makes your research faster thanks to: • A close partnership with maternity wards • Regulatory compliance (legal authorization, ethical compliance) • High-quality cells (purity, serological testing, viability, characterisation) adaptable to customers’ needs (quantity, HLA genotyping) • Reliable source of cells • Personalised after-sales services carried out by scientists Please contact us for more information at contact@abcell-bio.com

5 rue Henri Auguste Desbruères Evry, Ile-de-France, 91030 FranceWHO ? Abcell-bio is a French biotechnology company which provides a reliable source of human primary cells isolated from perinatal tissues and adequate culture media. WHAT ? Abcell-bio is specialized in production of: • Hematopoietic Cells isolated from cord blood or peripheral blood: CD34+ Hematopoietic Progenitors, MonoNuclear Cells from cord blood (MNC), Peripheral Blood Mononuclear Cells (PBMC) • Endothelial cells isolated from umbilical cord or cord blood: Endothelial Progenitor Cells (EPC), Human Umbilical Vein Endothelial Cells (HUVEC), Human Umbilical Artery Endothelial Cells (HUAEC) • Cell Culture Media: production of cell culture media dedicated to human primary cells HOW ? Abcell-bio has a unique expertise: the company controls the entire process from blood collection in maternity wards to the production of high-quality cells in dedicated laboratory facilities Thanks to its expertise, Abcell-bio makes your research faster thanks to: • A close partnership with maternity wards • Regulatory compliance (legal authorization, ethical compliance) • High-quality cells (purity, serological testing, viability, characterisation) adaptable to customers’ needs (quantity, HLA genotyping) • Reliable source of cells • Personalised after-sales services carried out by scientists Please contact us for more information at contact@abcell-bio.com

21 quai du Clos des Roses, 60200 Compiègne, FRANCEAbliance owns key technologies and constantly innovates to develop next generation antibodies. Our team of experts closely works with research laboratories, diagnostic industry, clinical research and biopharmaceutical industry actors to understand the needs of each purpose, its regulatory environment and economic constraints. Abliance provides antibodies that perform in their application by designing unique solutions.

Compiègne, Hauts-de-France, 60200 FranceAbliance owns key technologies and constantly innovates to develop next generation antibodies. Our team of experts closely works with research laboratories, diagnostic industry, clinical research and biopharmaceutical industry actors to understand the needs of each purpose, its regulatory environment and economic constraints. Abliance provides antibodies that perform in their application by designing unique solutions.

34 Avenue du 21 Août 1944 Bellegarde, Centre-Val de Loire, 45270 FranceACM Pharma, your partner specialized in contamination control. ACM Pharma offers a wide range of microbiology services (development, validation, suitability, test, training and consulting) of your new products or in-process control according to the main standards in force: Eur Ph, USP, EN ISO standards. The analyzes are carried out in laboratories dedicated to each type of analysis in an environment in accordance with standard NF EN ISO / IEC 17025 and cGMP.

6 rue Cognac Jay Paris, 75007 FranceLe laboratoire BALAZS fait parti du groupe Air Liquide. Nous analysons les produits chimiques, l'eau ultra pure ainsi que les gaz.

4 Rue Barthelemy Danjou Boulogne-Billancourt, Île-de-France, 92100 FranceAIXIAL is the CRO of Alten Group, a global leader in Engineering and High Added-Value services with 30 000 employees worldwide and revenues of 2 Billion Euros in 2017 (www.alten.com). With more than 500 people and a strong and steady growth of 20%, AIXIAL is among the Top 5 European full-services CROs with a planned extension in the USA. Our main Departments are Clinical Operations, Clinical Data Science, Vigilance & Medical Information, Regulatory Affairs & Quality Management, Real-World Data. Our philosophy is to be a flexible and agile Digital Solution Provider for our clients, by proposing taylor-made solutions to address each specific situation of a client rather than always applying the same processes and solutions. - Flexibility in our engagement models: Workpackages, Functional Services Platforms, Consultancy - Optimization of your timelines and budget, Mitigation of risks: Study methodology, feasibility studies (countries, sites), Risk-Based Monitoring, Patient recruitment and retention - Digitalization: CTMS, eTMF, eISF (Veeva), eICF, eCRF, ePRO

18, rue Troyon 75017 PARIS FranceAJC Pharma manufactures pharmaceutical forms of dry powder, granules, uncoated tablets, film-coated tablets and capsules.

Paris 12 Rue Charlot 75003 Paris, France Paris, Paris, 75003 FranceAlira Health is an international patient-centric and technology-enabled advisory firm whose mission is to humanize healthcare. We work with healthcare and life sciences organizations looking for support across their entire solutions lifecycle, from development to medical care, through real-world evidence. Our integrated and multidisciplinary team of over 700 scientists, strategists, economists, clinicians, and biostatisticians collaborate across our North American, European, and Asian offices and advise 80% of the top 50 of MedTech companies and 75% of the top 50 of Pharma companies.

55 Rue La Boétie,1st floor Paris, Paris, 75008 FranceAlira Health is an international patient-centric and technology-enabled advisory firm whose mission is to humanize healthcare. We work with healthcare and life sciences organizations looking for support across their entire solutions lifecycle, from development to medical care, through real-world evidence. Our integrated and multidisciplinary team of over 700 scientists, strategists, economists, clinicians, and biostatisticians collaborate across our North American, European, and Asian offices and advise 80% of the top 50 of MedTech companies and 75% of the top 50 of Pharma companies.

9 Rue d' Argenson Paris, Île-de-France, 75008 FranceAnalysis Group has a global footprint of integrated health care research capabilities. Across offices in North America, Europe, and Asia, we leverage our distinguished network of advanced-degree consultants, affiliated experts, and key opinion leaders to carry out an extensive range of work that includes real-world data (RWD) and real-world evidence (RWE) studies, post-marketing safety and effectiveness studies, indirect treatment comparisons, patient-reported outcomes (PROs), systematic literature reviews (SLRs) and meta-analysis, and AI-aided data solutions. Our clients benefit from our highly qualified teams across the world, which have substantial knowledge of local data, laws, and regulations but are also able to leverage our entire firm’s depth of expertise and integrate it seamlessly with local resources. We have supported the approval, launch, and market acceptance of numerous life sciences innovations in the US, EU and individual European countries. We have also provided expert input and testimony to regulatory and health technology assessment (HTA) bodies.

3 rue Joseph et Marie Hackin 75016 PARISARVALIS - Vegetable Institute For technological agriculture, efficient and sustainable resolutely Improve farm competitiveness, create opportunities, improve the profitability of production and chains and satisfy consumers and citizens are the objectives ARVALIS Institute plant. The expertise to farmers and industries A network of engineers and experts present on the national territory ARVALIS Institute plant, applied research organization, product technical and economic references and directly applicable in the agricultural production systems. Research stations, experimental sites, farms application, laboratories, the Institute has 35 sites located throughout the national territory. The teams are piloting studies at different levels of scale: - the plant: varietal characterization, development of biotechnologies - the plot: technical route; protection; nutrition; implantation techniques, crop protection products or applications. - exploitation and watershed: risk management point and diffuse pollution, organic status and soil fertility, biodiversity management, greenhouse gases greenhouse effects and conducted rotations, operating economics and competitiveness. The Institute's jurisdiction covers production techniques, harvesting, storage and preservation as well as the qualitative aspects of productions for all opportunities. The institute offers training and disseminates information through a strong presence in the press or on its own information channels: Agricultural Outlook, ARVALIS CETIOM information, ARVALIS.fr, information meetings and symposia, pamphlets. It also offers farmers and technicians operational tools, often computerized, for the conduct of crops.

56 Rue de Landres 75008 ParisASCOPHARM and the NOVASCO Group represent one of the most proactive Contract Research Organization in the field of Clinical Research in Europe. Founded in 1995 the original company, ASCOPHARM has now been raised to a full clinical and medical service group. Information on activities and structures can be found in History section and Global Group. The company has now specificities and expertise in a number of aspects of clinical research and post marketing support. Apart from standard services that other company may also offer, ASCOPHARM and the NOVASCO Group have raised up expertise in certain therapeutic fields (Oncology, Transplant, Immune modulators, Rheumatology, Cardiovascular disease…). The Group has also developed original services for site management and support (Site CRA services). Together will all services offered, ASCOPHARM has strongly developed its expertise in Information Technologies and Computer Software. Original tools have been developed (eCRF, Project Management tools, etc…) and an IT company has been integrated to the group. General structure is developed in Global Group while services are described in other sections.

Paris, FranceLa recherche et l’enseignement font partie de nos missions. Nous faisons de la recherche pour améliorer en permanence les soins et mettre en place de nouveaux traitements. En France, la moitié de la recherche clinique s’effectue dans les hôpitaux de l’AP-HP. La recherche vous permet de bénéficier des traitements les plus récents et de participer, aux côtés de nos médecins et soignants, aux progrès de la médecine. Dans un hôpital universitaire, vous avez la possibilité de participer à un « essai clinique » ou à un « essai thérapeutique », mais seulement avec votre accord explicite. L’essai auquel vous participez est placé sous le contrôle d’un comité d’éthique et vous signez un « consentement.

Paris, Île-de-France FranceLa recherche et l’enseignement font partie de nos missions. Nous faisons de la recherche pour améliorer en permanence les soins et mettre en place de nouveaux traitements. En France, la moitié de la recherche clinique s’effectue dans les hôpitaux de l’AP-HP. La recherche vous permet de bénéficier des traitements les plus récents et de participer, aux côtés de nos médecins et soignants, aux progrès de la médecine. Dans un hôpital universitaire, vous avez la possibilité de participer à un « essai clinique » ou à un « essai thérapeutique », mais seulement avec votre accord explicite. L’essai auquel vous participez est placé sous le contrôle d’un comité d’éthique et vous signez un « consentement.

Saint-Cloud, Île-de-France, 92210 FranceAthena provides development services, dossier licensing, and scientific support.

106 Bureaux de la Colline Bat F2, 92213 Saint Cloud, FranceAthena provides development services, dossier licensing, and scientific support.

174 Quai de Jemmapes Paris 75010 FranceAureus Pharma offers custom databases, training, and database management products.

174 Quai de Jemmapes 75010 Paris – FranceAureus Sciences provides a range of scientific knowledge solutions enabling biopharmaceutical companies to better understand the relationships of biological targets to compounds under evaluation.

138 Avenue Victor Hugo Paris, Île-de-France, 75016 FranceExpert consultancy, contract research, and scientific software development at the intersection of artificial intelligence and chemistry. Leveraging decades of research in chemoinformatics, AVANTIA CHEM accelerates drug discovery, molecular design, chemical innovation, and provides related software tools, support, and licensing services.

28, rue du Docteur Roux Paris, 75015 FranceAXENIS is a service company using humanized mice as preclinical models in immunology, for the pharmaceutical industry, biotechnology companies and academic research.

45 rue de Pommard, F-75012 Paris, FranceAxyntis offers subcontracting services for markets such as life sciences, fine specialty chemicals (electronics, etc.) and coloring agents.

Parc d’activités du Pas du Lac 10 bis, avenue Ampère 78 180 Montigny-le-Bretonneux FranceBertin Instruments is a brand of CNIM Group, dedicated to innovative measurement and sampling solutions for key worldwide markets such as: Lab Equipment (sample preparation, air sampler) Nuclear Instrumentation (radon professional monitoring, environmental radiation monitoring systems, radiation portal monitors, health physics) Defense, Security and Safety / Oil & Gas (CBRN, gas detection, optronics) Our instruments allows our customers to measure, sample and detect invisible elements (DNA, gases, ionizing radiation, night concealed targets…). Our customized sales and R&D approach is based on: a product-specific and customer-centered organization a global presence with a wide network of local partners targeted markets where our engineers can stand out with technological excellency a high technical & scientific digital support

Parc d'Activité du Pas du Lac 10 bis avenue Ampère Les Yvelines, 78180 Montigny-le-Bretonneux FranceBertin Pharma, a subsidiary of Bertin Technologies, offers preclinical/clinical, pharmaceutical development, biosafety, and biomarker assay tools and services.

Parc d’activités du Pas du Lac 10 bis avenue Ampère Montigny le Bretonneux, 78180 FranceBertin Pharma, a subsidiary of Bertin Technologies, offers preclinical/clinical, pharmaceutical development, biosafety, and biomarker assay tools and services.

14, rue de la Beaune Bâtiment C, 2ème étage Montreuil, Ile-de-France, 93100 FranceBforcure provides services (PCR, qPCR, RT-PCR, RT-qPCR, multiplex PCR) using existing assays and custom designed assays. Services are performed on standard qPCR machines or assays can be optimized to work on our ultra fast machines.

Institut Pasteur, Building F. Jacob 28 rue du Docteur Roux Paris, 75015 FranceBIOASTER is a Technology Research Institute dedicated to Microbiology & Infectious Diseases. BIOASTER is a non-profit organization aiming to provide our industrial partners with innovative scientific and technological solutions to accelerate the development of diagnostic, prophylactic, therapeutic or more broadly life science products. We design and implement tailored technological solutions to open new areas of opportunities or tackle technological barriers identified in product developments.

17, Rue Olof Palme 94000 CRETEIL FranceWe offer our customers a unique panel of assays aimed at measuring different cell metabolism markers. These markers (enzymes, substrates,…) will allow either a global exploration or a specific analysis of a narrower part of cell metabolism. Using our performant technology, it becomes possible to evaluate the respective impact of each metabolism in cell behavior and to compare precisely cell function in a longitudinal manner. Biochemikon services cover the full spectrum from standard methods through to cutting-edge custom approaches developed using latest biological insights and specially developed new assays.

22 Rue Adam-Ledoux Courbevoie, 92400 FranceBioexpert is an independent provider of research services in the life sciences. The company takes in charge the practical steps of execution of the projects. This company works in the Paris region. Life sciences specialist: in vitro and in vivo experiments. Non-exhaustive list of services: Management and training of teams for the realisation of projects Animal experimentation (mouse, rat): Chemo-induced cancer model, Xenogenic cancer model, Inoculations: Intraperitoneal, Intramuscular, Subcutaneous, Intravenous, Intra ocular injections; -Gavage Samples : Blood, gametes, bone marrow, aorta, aqueous humour, retina, pigment epithelium, choroid, iris and ciliary body, etc. Genotyping and management of genetically modified mice and breeding management, Fertility studies, Behavioural testing Cell biology : Cell culture: cell lines, primary cultures: endothelial stem cell, mesenchymal stem cell Cytotoxicity tests In vitro angiogenesis tests - on endothelial cells: clonogenicity test, secondary/tertiary colony formation test, functional tests: Migration, Tube formation, Wound healing Marker studies Immunofluorescence (Flow Cytometry, microscopy) Immunohistochemistry and Biochemistry (Immunoprecipitation, Western Blot), ELISA, Production of monoclonal antibodies against surface molecules: Production of monoclonal antibodies against surface molecules: Production by transfection of a high producing line of the antigen of interest, purification by tag, immunisation of mice/rats, fusion, selection, obtaining monoclonal hybridomas and production/purification of the desired antibodies Coupling of antibodies with fluorochromes Study of platelet functions: Aggregation, degranulation - secretion, activation, adhesion and spreading, bleeding time, hemodynamic thrombosis formation, FeCl3 model thrombosis,

32 Rue Olympe de Gouges VITRY-SUR-SEINE, 94400 FranceBiolepsis is a company specializing in the research and provision of human biological samples.

102 Avenue Gaston Roussel Romainville, Île-de-France, 93230 FranceBiopredic International is a French biotechnology company with 30 years of experience in designing and manufacturing human and animal assay systems. Biopredic International has a presence worldwide, with many logistic and production center around the world and is distributed globally by many actors on the market.

Domain de Vivert Batiment 220 78350 Jouy-en-Josas, FranceBioProtein Technologies offers protein purification, pharmacology, and human therapeutic proteins and vaccines in transgenic rabbit milk.

5, rue de labbé de lEpée Paris 75005 FranceBioQuanta offers molecular modeling, data generation, structure-activity prediction, target identification, optimization services, and toxicity prediction.

Parc Val Saint Quentin - Bâtiment H 2 Rue René Caudron 78960 Voisins-le-Bretonneux FranceThe Boston Scientific Corporation (abbreviated BSC) is a worldwide developer, manufacturer and marketer of medical devices whose products are used in a range of interventional medical specialties, including interventional radiology, interventional cardiology, peripheral interventions, neuromodulation, neurovascular intervention, electrophysiology, cardiac surgery, vascular surgery, endoscopy, oncology, urology and gynecology. Boston Scientific is primarily known for the development of the Taxus Stent, a drug-eluting stent which is used to open clogged arteries.[3] With the full acquisition of Cameron Health in June 2012, the company also became notable for offering a minimally invasive implantable cardioverter-defibrillator (ICD) which they call the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD).

70 av. Marx Dormoy 92120 Montrouge FranceOur core business is the study of pharmacokinetics (PK) in the human brain. The molecules that we study can have CNS targets as well as peripheral targets.

29, quai des Grésillons 92230 Gennevilliers Cedex, France

29 Quai des Gresillons Gennevilliers, Île-de-France, 92230 France

7 rue Labie 75017 Paris FranceCDM Lavoisier specializes in the production of pharmaceutical drugs and medical devices.

Paris, Île-de-France FranceCDM Lavoisier specializes in the production of pharmaceutical drugs and medical devices.

137 Rue d' Aguesseau Boulogne-Billancourt, Île-de-France, 92100 FranceCegedim Health Data is a division of Cegedim Group, an innovative technology and services group specializing in healthcare for more than 50 years. Cegedim Health Data provides real-world data (RWD) cohorts and real-world evidence (RWE) to drive research and improvements in patient outcomes in compliance with current regulations, including GDPR. The THIN®️ databases cover millions of electronic health record extracts across seven countries: the UK, France, Germany, Italy, Spain, Belgium and Romania. Cegedim Health Data works with researchers, health authorities, healthcare practitioners, pharma and medical device companies. It supports them in R&D, market access, medical affairs with the aim of improving public health.

Évry, Île-de-France FranceCellvax offers in vivo and in vitro disease models and imaging services.

4, rue Pierre Fontaine 91000 Evry FranceCellvax offers in vivo and in vitro disease models and imaging services.

Fontenay-sous-Bois, Île-de-France, 94120 FranceCenexi offers contract manufacturing for tablets,hard gelatine capsules,ampoules,syrups,packaging and suppositories.

Fontenay-sous-bois, FranceCenexi offers contract manufacturing for tablets,hard gelatine capsules,ampoules,syrups,packaging and suppositories.

Campus de Paris-Saclay / Laboratoire SPMS 3 Rue Joliot Curie Ile de France, 91190 FranceCentraleSupélec is a forward-looking engineering school, built on nearly two centuries of excellence and innovation. Born from two great French scientific traditions—the École Centrale des Arts et Manufactures, founded in 1829 to support the Industrial Revolution, and Supélec, created in 1894 to address the upheavals in electricity and telecommunications—it today embodies a school resolutely focused on the challenges of our time. Here, we train engineers called upon to think big, act quickly, and combine scientific rigor with social commitment. Each year, nearly 1000 students join its campuses to build a more sustainable, more equitable, and more inventive world. Their backgrounds are diverse, their aspirations multiple. And it's this diversity that makes CentraleSupélec so strong. Leaning against theParis-Saclay UniversityRanked among the best in the world, the school deploys a model unique in Europe, combining academic excellence, research power, and international openness. It cultivates a spirit of profound innovation, backed by technology, and always humanist. It believes in hybrid engineering: capable of crossing disciplines, of inventing new languages between science, industry, society and culture. Faced with the emergencies of the century—climate, health, industrial, geopolitical—CentraleSupélec intends to exert influence and train more, and better. Its 2023-2032 strategic plan sets a clear course: to double the number of graduates, while reaffirming high standards and excellence. It is also a commitment: to make knowledge more accessible, pathways more diverse, and campuses more open. CentraleSupélec is a school for those who want to understand the world and transform it. A school where we learn to learn, to undertake, and to cooperate. A school that trains citizen-engineers, both builders and pathfinders.

Campus de Paris-Saclay 3 Rue Joliot Curie Ile de France, 91190 FranceCentraleSupélec is a forward-looking engineering school, built on nearly two centuries of excellence and innovation. Born from two great French scientific traditions—the École Centrale des Arts et Manufactures, founded in 1829 to support the Industrial Revolution, and Supélec, created in 1894 to address the upheavals in electricity and telecommunications—it today embodies a school resolutely focused on the challenges of our time. Here, we train engineers called upon to think big, act quickly, and combine scientific rigor with social commitment. Each year, nearly 1000 students join its campuses to build a more sustainable, more equitable, and more inventive world. Their backgrounds are diverse, their aspirations multiple. And it's this diversity that makes CentraleSupélec so strong. Leaning against theParis-Saclay UniversityRanked among the best in the world, the school deploys a model unique in Europe, combining academic excellence, research power, and international openness. It cultivates a spirit of profound innovation, backed by technology, and always humanist. It believes in hybrid engineering: capable of crossing disciplines, of inventing new languages between science, industry, society and culture. Faced with the emergencies of the century—climate, health, industrial, geopolitical—CentraleSupélec intends to exert influence and train more, and better. Its 2023-2032 strategic plan sets a clear course: to double the number of graduates, while reaffirming high standards and excellence. It is also a commitment: to make knowledge more accessible, pathways more diverse, and campuses more open. CentraleSupélec is a school for those who want to understand the world and transform it. A school where we learn to learn, to undertake, and to cooperate. A school that trains citizen-engineers, both builders and pathfinders.

Paris, Île-de-France FranceCEPiA specializes in the manufacturing of opiates/opioids, coricosteroids, hormones, biotech, fermentation, prostaglandins and synthesis products.

10-12 rue Roland Moreno Frépillon, 95740 FranceFor over 35 years, Cerba Research has been setting the industry standard for exemplary Laboratory conduct. Today, across five continents, with a focus on precision medicine, we are changing the paradigm of the central lab’s role in complex clinical research. From protocol inception through development and to market, our passionate experts deliver the highest quality specialized and personalized laboratory and diagnostic solutions. Cerba Research provides testing in therapeutic areas such as Cardiovascular diseases, Infectious diseases (microbiology, vaccine studies on virology and other IDs), Inflammatory disorders, Autoimmune diseases, Oncology, Metabolic diseases and Rare/Orphan diseases. Performing testing from Phase I to Phase IV studies. Cerba Research’s central lab services include routine testing, custom assay development, biobanking & storage, global project management & logistical support, and operational support (including logistics, sample handling, kit building & data management).

155, rue du Faubourg Saint-Denis Paris, 75010 FranceCerom provides cardiovascular analytical service.

102 avenue Gaston Roussel Romainville, 93230 FranceCHEM-X-INFINITY provides original libraries of small organic molecules and fragments.

14 Rue de la Beaune Montreuil, 93100 FranceCherry Biotech is a world-class PharmaTech, French leader in early preclinical 3D cell culture and Organ on Chips/Microphysiological systems. Our expertise and technology allow maintaining vascularized and immunocompetent organoids of any organ in a standard multiwell plate. Already used by pharma and biotech companies in their early drug development phases (immuno- oncology, tox-efficacy, Pharmacokinetics), we are also providing services for proof of feasibility.

Immeuble le Doublon - 11 Avenue Dubonnet, 92400 Courbevoie - FranceChiesi farmaceutici offers drug development, drug discovery, and clinical trials.

Incubateur de l’Institut de la Vision (Voir et Entendre), 74 rue du Faubourg Saint Antoine, 75012 Paris – FranceCILcare is an R&D services company dedicated to hearing deficiencies. CILcare supports biotechs, medtechs and pharmas from all over the world in their preclinical and clinical development in hearing loss and tinnitus. CILcare has developed a unique lab platform gathering acoustic, electrophysiology, behavioral, histology and imaging technologies to perform preclinical efficacy studies on different models of hearing loss and tinnitus in rodents as well as pharmacokinetics studies to assess the exposure of the candidates in the inner ear and other targeted organs. The three founders began working on issues related to the aging population at pharma giant Sanofi – in complementary disciplines. They realized there was a niche but growing market servicing research into hearing deficiencies and founded CILcare in 2014. Today, the 9-person team is considered the worldwide leader of services in hearing research and development.

53 avenue Montaigne Paris, 75008 FranceWe are a consulting firm specialised in the fields of Global HEOR, Access and Pricing, informing Access and HTA strategy from early to late stage product development. For launch preparation, we provide integrated team of experts who develop all necessary core deliverables and strategic guidance for successful HTA submissions.

215 Rue du Faubourg Saint-Honoré Paris, Île-de-France, 75008 FranceWe are a consulting firm specialised in the fields of Global HEOR, Access and Pricing, informing Access and HTA strategy from early to late stage product development. For launch preparation, we provide integrated team of experts who develop all necessary core deliverables and strategic guidance for successful HTA submissions.

74 Rue Des Suisses Nanterre, 92000 FranceCliniSciences is a European distributor of products & services from suppliers based all around the world. With a direct presence in 18 countries, CliniSciences serves customers through its own commercial and technical teams in Austria, Belgium, Denmark, Finland, France, Germany, Iceland, Ireland, Italy, the Netherlands, Norway, Poland, Portugal, Spain, Sweden, Switzerland, the United Kingdom, and the United States. Through these companies, CliniSciences offers a broad portfolio of life science reagents, instruments and services for research and diagnostic applications. Our product range includes reagents, antibodies, cells, assay kits, instruments, and a strong offering of human biological samples, including blood-derived products, tissues, primary cells, biofluids, DNA/RNA and other clinically relevant biospecimens. Our services include antibody development, peptide and protein synthesis, bulk manufacturing, humanization, custom production and other tailored solutions to support life science, biotech and diagnostic projects.

74 rue des Suisses Nanterre, France, 92000 FranceCliniSciences is a European distributor of products & services from suppliers based all around the world. With a direct presence in 18 countries, CliniSciences serves customers through its own commercial and technical teams in Austria, Belgium, Denmark, Finland, France, Germany, Iceland, Ireland, Italy, the Netherlands, Norway, Poland, Portugal, Spain, Sweden, Switzerland, the United Kingdom, and the United States. Through these companies, CliniSciences offers a broad portfolio of life science reagents, instruments and services for research and diagnostic applications. Our product range includes reagents, antibodies, cells, assay kits, instruments, and a strong offering of human biological samples, including blood-derived products, tissues, primary cells, biofluids, DNA/RNA and other clinically relevant biospecimens. Our services include antibody development, peptide and protein synthesis, bulk manufacturing, humanization, custom production and other tailored solutions to support life science, biotech and diagnostic projects.

110 Avenue Pierre Brossolette Malakoff, 92240 FranceClinSearch is a European Health Research Organizationwhich provides Consultancy and Operational services for Medical Device and Drug Development. We offer more than quality at each step of your project, more than a highly qualified team, more than customer satisfaction… ClinSearch is committed to offer cost-effective solutions for designing and managing clinical evaluations, real-life studies or any other healthcare assessment. This is why ClinSearch is known as a company committed to results and has earned a reputation for delivering practical, measurable and high added-value data.

15 Rue Georges Clemenceau Orsay, Île-de-France, 91400 FranceLe Laboratoire de Chimie Physique (LCP) est une unité mixte de recherche (UMR 8000) de l’Université Paris-Sud et du CNRS, localisée sur le campus de la faculté des Sciences d’Orsay.

77 Boulevard de la République La Garenne-Colombes, Île-de-France, 92257 FranceCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

Cnrs/ Umr 7241 - Inserm U1050 11, Place Marcelin Berthelot Paris Cedex 05, 75231 FranceThe Center for Interdisciplinary Research in Biology (CIRB) is a novel Collège de France / CNRS / INSERM research structure located at the Collège de France in the Center of Paris. Nine teams from different horizons have recently founded this structure with the spirit to foster new collaborations within biological domains and across the usual disciplinary divide. In the long term the nine founding groups, specialized in the fields of infectious diseases, neurosciences and cardio-vascular research, will be rejoined by a similar number of new groups, primarily junior groups, including chemists, physicists and mathematicians with a strong interest for biological sciences. The new Center will benefit from being in the vicinity of several other laboratories and from an extraordinary rich intellectual milieu, with conferences that cover all aspects of knowledge. Outside of Collège de France, CIRB has developed strong interactions with high profile neighboring institutions, in particular the Ecole Normale Supérieure and the Curie Institute.

92 avenue Charles De Gaulle NEUILLY-SUR-SEINE, 92200 FranceAt Vulcain, we optimize operations and the supply chain for maximum efficiency, while reducing costs and improving the quality of industrial processes. Thanks to our technical, process and digitalization expertise, we integrate innovative solutions that optimize each stage of projects or production. Our control of Quality and Regulatory Compliance guarantees that your operations meet the most stringent standards. At the same time, our engineering capabilities and R&D contribute to the development of cutting-edge technologies, combining eco-design and the control of industrial or environmental risks for operational excellence and increased energy efficiency. In order to meet the current and future challenges of the sector, while ensuring sustainable and effective results. In this way, we strengthen the competitiveness of our customers, allowing them to meet growing requirements with agility and precision.

7 avenue du Hoggar Les Ulis, 91940 FranceCortecNet is a Stable Isotopes-driven company, devoted to identifying, developing and marketing innovative products in the fields of NMR, MS, MRI, and PET. These techniques play a key role in the characterization of the structure and dynamics of proteins, bio-molecules and materials, and in metabolic imaging applications. However, their success strongly relies on labeling techniques. The driving force of our company is therefore to providing to the MR and MS communities, both in academia and in industry, isotopically-enriched compounds the best adapted for their research purposes

44 Rue d'Alésia Paris, Île-de-France, 75014 FranceThe CTCPA, center of collective research for companies which produce canned and dehydrated foods. The CTCPA achieves its general interest missions thanks to a fiscal contribution paid by French companies working in the canned and dehydrated food sector. These companies represent nearly 40% of the center’s resources. The missions include: collective research programs transfer of technology, expertise, representing the profession, scientific, technical, and regulatory watch technical support to professionals through question and answer service, valorization of the research results The research orientations of the CTCPA and the nature of its general interest missions are established through a contract of objectives and means lasting many years. This contract is defined between the minister in charge of the food sector and the concerned professional syndicate (Fiac). Each year food companies choose their desired research projects for the coming year. The result of each research project is available to any European Union industry with products in the area of competence of TFA, by simple request to the documentation center.

10 Rue Vauquelin Paris, 75005 FranceCyprio develops and commercializes physiologically-relevant 3D models: 1/- 3D organoids of primary human and rat hepatocytes,(HepatoPearls) and of HepaRG cell lines (HCLPearls), encapsulated within alginate solution, allowing self assembly of cells in organoids in less than 7 days, protection of these organoids, easy manipulation, and high throughput measures of DMPK, toxicity, DDI ... 2/- A customized encapsulation service for any cell line provided by our clients (cancer line, kidney, intestine, etc...) to grow organoids (e.g. for disease modeling, or subcloning of cancer lines). Cyprio's cutting edge patented technology (originated from ESPCI) is based on the high throughput encapsulation of a precise number of cells within a liquid-core alginate capsule. In this porous microenvironment, the cells can self-assemble to form a 3D structure, which more accurately reproduces functionalities of the tissue under study than monolayer 2D cell cultures. These easy to handle organoids are adaptable to any bioassay (number of organoids capsules per well from 1 to 200) or bioimaging , and can predict liver in vivo response with improved precision and can represent an interesting alternative to animal models For more information, see our web site : https://www.cyprio.fr/

102, avenue Gaston Roussel Romainville, Ile de France, 93230 FranceCyprio develops and commercializes physiologically-relevant 3D models: 1/- 3D organoids of primary human and rat hepatocytes,(HepatoPearls) and of HepaRG cell lines (HCLPearls), encapsulated within alginate solution, allowing self assembly of cells in organoids in less than 7 days, protection of these organoids, easy manipulation, and high throughput measures of DMPK, toxicity, DDI ... 2/- A customized encapsulation service for any cell line provided by our clients (cancer line, kidney, intestine, etc...) to grow organoids (e.g. for disease modeling, or subcloning of cancer lines). Cyprio's cutting edge patented technology (originated from ESPCI) is based on the high throughput encapsulation of a precise number of cells within a liquid-core alginate capsule. In this porous microenvironment, the cells can self-assemble to form a 3D structure, which more accurately reproduces functionalities of the tissue under study than monolayer 2D cell cultures. These easy to handle organoids are adaptable to any bioassay (number of organoids capsules per well from 1 to 200) or bioimaging , and can predict liver in vivo response with improved precision and can represent an interesting alternative to animal models For more information, see our web site : https://www.cyprio.fr/

6 Rue Jean Calvin IPGG - 2nd floor Paris, 75005 FranceCyprio develops and commercializes physiologically-relevant 3D models: 1/- 3D organoids of primary human and rat hepatocytes,(HepatoPearls) and of HepaRG cell lines (HCLPearls), encapsulated within alginate solution, allowing self assembly of cells in organoids in less than 7 days, protection of these organoids, easy manipulation, and high throughput measures of DMPK, toxicity, DDI ... 2/- A customized encapsulation service for any cell line provided by our clients (cancer line, kidney, intestine, etc...) to grow organoids (e.g. for disease modeling, or subcloning of cancer lines). Cyprio's cutting edge patented technology (originated from ESPCI) is based on the high throughput encapsulation of a precise number of cells within a liquid-core alginate capsule. In this porous microenvironment, the cells can self-assemble to form a 3D structure, which more accurately reproduces functionalities of the tissue under study than monolayer 2D cell cultures. These easy to handle organoids are adaptable to any bioassay (number of organoids capsules per well from 1 to 200) or bioimaging , and can predict liver in vivo response with improved precision and can represent an interesting alternative to animal models For more information, see our web site : https://www.cyprio.fr/

15, rue du Helder Paris, 75 439 FranceDanone focuses on research in nutrition, microbiology, immunology, and neuroscience.

8 Rue Jean Antoine de Baïf Paris, 75013 FranceDeepLife is a pioneering biotech company transforming drug development through artificial intelligence (AI) and digital twin technology. Our end-to-end drug repurposing platform leverages an advanced AI-driven engine that maps cell-type specific networks, utilizing over 100 million harmonized single-cell omics data points to help researchers identify drug targets, explore intricate gene/protein interactions, and analyze complex regulatory networks with unprecedented precision and depth. Our innovative approach focuses on target identification and drug repurposing, dramatically accelerating timelines by identifying new therapeutic applications for FDA-approved drugs and molecules with established safety profiles. By employing sophisticated computational models that integrate multi-omics analytics, we pinpoint critical targets and biomarkers capable of reverting diseased cells to healthy states. Our primary research domains concentrate on autoimmune disorders like inflammatory bowel disease, psoriasis, and atopic dermatitis, as well as complex neurodegenerative diseases that require innovative therapeutic strategies. Supported by $10M Series A funding, and collaborating strategically with Beiersdorf on cutting-edge projects in skin diseases and aging, DeepLife stands at the intersection of computational innovation and transformative patient care. Through our AI-driven simulations and comprehensive multi-omics analytics, we empower pharmaceutical partners to develop precision therapies that are not only more targeted but also significantly faster and more cost-effective in addressing complex medical challenges.

42 rue de glatigny vernon, 27200 FranceDeepLife is a pioneering biotech company transforming drug development through artificial intelligence (AI) and digital twin technology. Our end-to-end drug repurposing platform leverages an advanced AI-driven engine that maps cell-type specific networks, utilizing over 100 million harmonized single-cell omics data points to help researchers identify drug targets, explore intricate gene/protein interactions, and analyze complex regulatory networks with unprecedented precision and depth. Our innovative approach focuses on target identification and drug repurposing, dramatically accelerating timelines by identifying new therapeutic applications for FDA-approved drugs and molecules with established safety profiles. By employing sophisticated computational models that integrate multi-omics analytics, we pinpoint critical targets and biomarkers capable of reverting diseased cells to healthy states. Our primary research domains concentrate on autoimmune disorders like inflammatory bowel disease, psoriasis, and atopic dermatitis, as well as complex neurodegenerative diseases that require innovative therapeutic strategies. Supported by $10M Series A funding, and collaborating strategically with Beiersdorf on cutting-edge projects in skin diseases and aging, DeepLife stands at the intersection of computational innovation and transformative patient care. Through our AI-driven simulations and comprehensive multi-omics analytics, we empower pharmaceutical partners to develop precision therapies that are not only more targeted but also significantly faster and more cost-effective in addressing complex medical challenges.

Rue des Adèles Bâtiment 440 Orsay, 91400 FranceAccelerate and de-risk the development of Biotech/Pharma therapeutic antibodies with an integrated optimization solution to achieve expected characteristics in less than 3 months.

DRF – Institut Joliot /SIMoS/Bât. 152 Pièce 35A Gif-sur-Yvette Cedex , F-91191 FranceAccelerate and de-risk the development of Biotech/Pharma therapeutic antibodies with an integrated optimization solution to achieve expected characteristics in less than 3 months.

DRF – Institut Joliot /SIMoS Bât. 152 Pièce 35A Gif-sur-Yvette Cedex , F-91191 FranceAccelerate and de-risk the development of Biotech/Pharma therapeutic antibodies with an integrated optimization solution to achieve expected characteristics in less than 3 months.

6-8 rue du 4 septembre Batiment B - Le Poversy 92130 Issy Les MoulineauxDelpharm provides development and production of pharmaceutical products.

79 AVENUE LEDRU ROLLIN PARIS, Alsace, 75012 FranceDiscngine provides software and services for Life Science discovery

6 rue du Noyer Roissy-en-France, Roissy CDG, 95 734 FranceFounded in 2000, DIVERCHIM is the leading French company for organic synthesis of original molecules bringing its customers a top level expertise. DIVERCHIM is a Contract Research Organisation (CRO) in organic chemistry. Our teams combine experience in drug discovery and process development, medicinal chemistry, parallel synthesis, biochemical tools and fine chemicals to deliver you with unique chemistry solutions to achieve your requirements. Diverchim specifies in complex multi-steps synthesis, low temperature chemistry, asymmetric, organometallic, cyclopropane, pyrrolidine, oxetane chemistry... Besides Diverchim can scale-up existing processes or develop a new process for existing products. Our Custom Synthesis capabilities range from mg to cGMP kilogram scale. DIVERCHIM offers reference products for screening and building blocks for discovery (catalog).

5 rue Jean-Baptiste Clément Châtenay-Malabry, 92290 FranceDrugabilis offer includes solubility screenings, polymorphism, salt selection, crystallization test, formulation for animal dosing, or phase I formulation strategy set-up…

54 Rue Dunois Paris, 75013 FranceIntelligent and Automated Flow Cytometry Panel Design Platform.

6 Rue Cambacérès Paris, IDF, 75008 FranceThe life sciences consulting firm that combines the best human expertise with the latest AI technologies. We design pioneering strategies for global market access, drug pricing and pharmaceutical product development.

12-12 bis rue Jean Jaurès 92800 Puteaux • FranceELITech offers manufacturing and distribution of in vitro diagnostic equipment and reagents.

Puteaux, Île-de-France, 92800 FranceELITech offers manufacturing and distribution of in vitro diagnostic equipment and reagents.

172 Rue de charonne Paris 11, 75011 FranceElveflow® focuses on the development of high performance and Plug and Play flow control systems fitted to microfluidic research. We provide the only microfluidic flow control systems using Piezo technology and that enable blazing fast flow changes in your microdevice. Our team develops microfluidic instruments with unrivaled performances in accordance to researchers’ needs. Our product line is built around the best seller OB1 flow controller and includes all that is needed to control your microfluidic chip. All our instruments can be controlled at once on the same computer, through our software or Standard Development Kits.

85 avenue philippe auguste France Paris, france, 75011 FranceElveflow® focuses on the development of high performance and Plug and Play flow control systems fitted to microfluidic research. We provide the only microfluidic flow control systems using Piezo technology and that enable blazing fast flow changes in your microdevice. Our team develops microfluidic instruments with unrivaled performances in accordance to researchers’ needs. Our product line is built around the best seller OB1 flow controller and includes all that is needed to control your microfluidic chip. All our instruments can be controlled at once on the same computer, through our software or Standard Development Kits.

83 Avenue Philippe Auguste 75011 Paris FRANCEElveflow® focuses on the development of high performance and Plug and Play flow control systems fitted to microfluidic research. We provide the only microfluidic flow control systems using Piezo technology and that enable blazing fast flow changes in your microdevice. Our team develops microfluidic instruments with unrivaled performances in accordance to researchers’ needs. Our product line is built around the best seller OB1 flow controller and includes all that is needed to control your microfluidic chip. All our instruments can be controlled at once on the same computer, through our software or Standard Development Kits.

59, bd. Général Martial Valin 75015 Paris - FranceEmka TECHNOLOGIES develops, manufactures and sells hardware and software for studies in physiology, pharmacology and toxicology.

59, bd. Général Martial Valin Paris, 75015 FranceEmka TECHNOLOGIES develops, manufactures and sells hardware and software for studies in physiology, pharmacology and toxicology.

10 rue Vauquelin Paris, 75231 FranceESPCI ParisTech offers laboratories focused in various areas including organic chemistry, neurobiology, and genetics.

4 rue Pierre Fontaine EVRY-COURCOURONNES, Essonne, 91000 FranceEukarÿs develops and provides a technology which boosts biomanufacturing yields by 5 to 7 times in mammalian cells. Universally, and free from investment. This technology is an artificial enzyme, a synthetic RNA polymerase: it boosts mRNA-of-interest production, leading to high yields of biologics production (antibodies, proteins, viruses...). Benefits: - saves time in R&D: shortened process development, fewer batches - enhances the capacity to produce hard-to-express biologics - cuts costs and investment: fewer and/or smaller batches, smaller or fewer equipments

15 Rue Traversière Paris, 75012 FranceBianoGMP is a German company offering R&D scale oligonucleotides from few mg up to 500kg, top tier non-GMP & GMP capabilities and key technologies such as ASO, siRNA and CRISPR guide RNA. Looking for a one-stop shopping solution for your oligonucleotides projects? EuroAPI end-to-end platform ensures a smooth, time efficient and cost-effective transition between the different stages of your Drug candidates, from the early development & preclinical phases (BianoGMP), to the clinical and commercial phases (Frankfurt).

9 Avenue de Laponie Les Ulis, Île-de-France, 91940 FranceProvider of comprehensive CMC testing laboratory services for the pharmaceutical and biopharmaceutical sciences. Flexible service delivery model options include Fee for Service, Full Time Equivalents (FTE) and Professional Scientific Staffing (PSS). Includes all the following entities: EUROFINS AMATSI ANALYTICS SAS Eurofins Biolab S.r.l. Eurofins BioPharma Munich GmbH EUROFINS BIOPHARMA PRODUCT TESTING BIOLOGICS Eurofins Biopharma Testing Ireland Eurofins Lancaster Laboratories, LLC EUROFINS PHARMA QUALITY CONTROL Eurofins PHAST Eurofins PROXY Laboratories B.V. Eurofins Spinnovation Analytical

45 rue des Saints Pères Paris, Ile-de-France, 75006 FranceEverZom develops a new manufacturing platform of large-scale cGMP grade exosomes for research purposes and clinical studies based on a unique proprietary process. Our process, based on turbulence stimulation allows in average a 10-fold higher and a 10-fold faster increase in EV production per cell compared to starvation method for different cell lines. We also provide characterization services with an NTA, an Exoview, a Videodrop from Myriade and a flow cytometry platform.

51, avenue de Paris 94300 VINCENNES FranceIn 1969, Pr Philippe Masson creates Evic Ceba, laboratory located in Bordeaux, France, designated to pharmacological and toxicological experiments. The success of this first company and the expertise of its scientists naturally lead to the extension of the know-how to the global exploration of ingredients and products from the pharmaceutical, cosmetic, chemical and food fields: in 1987, creation of Evic Idec, clinical research organization on healthy subjects; in 1991, foundation of in vitro / ex vivo department (Evic Bio). In 2000 Evic Ceba becomes Evic France and expands its capacities abroad. In a world of internationalisation of the needs of the industry and globalisation of the markets, Evic France enlarges its service offer and creates with local partners research and evaluation centres in Brazil, Romania, Italy, Spain, China, thus introducing the renown “Evic” label. To optimize this new network of laboratories, EVIC International is created in 2005, meant to manage independently the group organisation and functioning. The purpose of EVIC International is to coordinate and harmonize the activity of the companies and induce them on a common level of excellence.

INRAE Domaine de Vilvert 4, avenue Jean Jaurès Bat221 JOUY EN JOSAS, 78352 FranceSince its creation Excilone has developed an unique expertise in sample’s analysis through the image or the molecular content. We use what we sell and we sell what we use Our dual approach of service provider as well as vendor of our solutions brings us an unequaled expertise on the performance and the use of our products that benefit our customers. Pharmaceutical and cosmetic companies, academic research labs and other CROs are all users of our services. Our R&D department allows us to regularly supplement our offer as recently with the isolation, characterization and analysis of extracellular vesicles from any type of sampling (blood, urine, milk, tissues, …). Our services are aimed at all private and academic labs that need to use operational analysis techniques without having to invest in expensive devices which also are time consuming to set protocols and to validate them. To reply to the needs of the scientific community about the analysis of samples through images or molecular content Excilone offers a wide range of services in Microgenomics, Nanogenomics, and Cellular Imaging. As the understanding of biological phenomena is now done at the scale of the cell, Excilone presents you the excellence in epsilon quantity.

6 Rue Blaise Pascal Élancourt, Île-de-France, 78990 FranceSince its creation Excilone has developed an unique expertise in sample’s analysis through the image or the molecular content. We use what we sell and we sell what we use Our dual approach of service provider as well as vendor of our solutions brings us an unequaled expertise on the performance and the use of our products that benefit our customers. Pharmaceutical and cosmetic companies, academic research labs and other CROs are all users of our services. Our R&D department allows us to regularly supplement our offer as recently with the isolation, characterization and analysis of extracellular vesicles from any type of sampling (blood, urine, milk, tissues, …). Our services are aimed at all private and academic labs that need to use operational analysis techniques without having to invest in expensive devices which also are time consuming to set protocols and to validate them. To reply to the needs of the scientific community about the analysis of samples through images or molecular content Excilone offers a wide range of services in Microgenomics, Nanogenomics, and Cellular Imaging. As the understanding of biological phenomena is now done at the scale of the cell, Excilone presents you the excellence in epsilon quantity.

Paris, FranceExonHit Therapeutics provides clinical validation, diagnostic tests, and RNA splicing.

Paris, Île-de-France FranceExonHit Therapeutics provides clinical validation, diagnostic tests, and RNA splicing.

80, Avenue de la grande armée Paris, 75017 FranceFareva offers contract manufacturing services including formulation, production, and filling.

74 Rue Jean-Jacques Rousseau Paris-1ER-Arrondissement, Île-de-France, 75001 FranceQui sommes nous? Une fédération au service des agriculteurs multiplicateurs depuis plus de 50 ans ! La FNAMS (Fédération Nationale des Agriculteurs Multiplicateurs de Semences) est une organisation professionnelle agricole spécialisée dans la multiplication des semences. Elle représente les 18 000 agriculteurs multiplicateurs de semences français. Sa mission est de promouvoir la production de semences française et défendre les intérêts des agriculteurs multiplicateurs de semences.

Bâtiment Le Ponant D 25, rue Leblanc Paris, 75015 FranceLe Commissariat à l’énergie atomique et aux énergies alternatives (CEA) est un organisme public de recherche à caractère scientifique, technique et industriel (EPIC).​ Acteur majeur de la recherche, du développement et de l'innovation, le CEA intervient dans le cadre de quatre missions : la défense et la sécurité, l'énergie nucléaire (fission et fusion), la recherche technologique pour l'industrie et la recherche fondamentale (sciences de la matière et sciences de l​a vie). S'appuyant sur une capacité d'expertise reconnue, le CEA participe à la mise en place de projets de collaboration avec de nombreux partenaires académiques et industriels.

Romainville, FranceGalapagos provides disease models, target discovery and screening, compound libraries, and medicinal chemistry.

27 Avenue du Québec, 91140 Villebon-sur-Yvette, France France Villebon-sur-Yvette, Île-de-France, 91140 FranceGEG-tech R&D team is focused on innovation in gene transfer tools and constantly innovate to improve lentiviral vector features, capabilities and safety. We aim at creating new tools which take every advantage of the lentivirus biology.

22, route 128 Gif sur Yvette, IDF, 91190 FranceGEG-tech R&D team is focused on innovation in gene transfer tools and constantly innovate to improve lentiviral vector features, capabilities and safety. We aim at creating new tools which take every advantage of the lentivirus biology.

1bis, rue de l’Internationale – Évry, 91002 FranceGenethon focuses their efforts in developing new vector and plasmid designs and contructing them in the application of gene therapy studies. Their expertise includes bioprocess development, bioanalytical development, and sample storage.

8 Rue de Rouen 2-8 rue de Rouen Porcheville, 78440 FranceGenEvolutioN®, a specialist in in vitro toxicology and in vitro genetic toxicology, is developing an innovative technique for their clients: the telomere / centromere micronucleus test differentiating the aneugene and clastogenic effect. This technique that we develop, coupled with our know-how, allows our highly experienced employees to significantly reduce the delivery time of study results (saving up to 4 weeks), while respecting quality and giving our customers the benefit of our personalized support in their projects. Specialist for genotoxicity of plant extractc (herbal medecine, and cosmetic ingredient), in standard Ames test , and using treat and wash method.

2-8 Route de Rouen Porcheville, 78440 FranceGenEvolutioN®, a specialist in in vitro toxicology and in vitro genetic toxicology, is developing an innovative technique for their clients: the telomere / centromere micronucleus test differentiating the aneugene and clastogenic effect. This technique that we develop, coupled with our know-how, allows our highly experienced employees to significantly reduce the delivery time of study results (saving up to 4 weeks), while respecting quality and giving our customers the benefit of our personalized support in their projects. Specialist for genotoxicity of plant extractc (herbal medecine, and cosmetic ingredient), in standard Ames test , and using treat and wash method.

172 rue de Charonne Le Dorian B2 75011 Paris, FranceGenewave is a development-stage diagnostics company that provides information to curb the spread of hospital-acquired infections and anti-microbial resistance.

147, Avenue Paul Doumer 92500 Rueil Malmaison FranceGenomeQuest provides large-scale genomic software applications.

Evry, FranceGenoSafe offers molecular analysis, immune response characterization, quality control of gene therapy products, and cell line/stem cell characterization.

2 rue des Gravilliers 75003 Paris FRANCEGenosphere Biotechnologies provides custom peptides, antibodies, genes, and sequencing services.

4, rue Pierre Fontaine Evry, 91058 FranceGenoSplice Technology offers next generation sequencing and microarray data analysis, with specific expertise in alternative splicing.

9, rue Lagrange, 75005 Paris, FranceGentaur is a supplier of life science research products.

19 avenue des Entrepreneurs 95400 Villiers Le Bel Villiers Le Bel, 95400 FranceGilson is a family-owned, leading innovator in sample handling, purification, and data management instruments and services for the life sciences industry. Since 1957 when we designed the first variable volume pipette, we have partnered with the scientific community to create solutions that help researchers advance the pace of discovery. Core to our mission to enable verifiable science, we intend our offers to support our customers policies for sourcing (e.g. « open system » goal), eco-responsibility and social inclusion too.

102, avenue Gaston Roussel Romainville, 93230 FranceHelios BioSciences builds dynamic models mimicking the behavior of cell signaling cascades to accelerate the selection of reliable therapeutic targets or biomarkers.

184 Rue du Faubourg Saint Antoine 75571 Paris FranceHopital Saint Antoine focuses on clinical research areas.

184 Rue du Faubourg Saint Antoine Hôpital Saint Antoine Paris, 75012 FranceHuman HepCell is a preclinical Contract Research Organization specialized in liver pathologies (fibrosis, HCV). Human HepCell is specialized in the evaluation of molecules on human normal and pathological cells and tissues.

1 Rue Pierre Fontaine Genopole Biocluster Campus 3 Évry, Île-de-France, 91058 FranceHybrigenics Services is a complete service provider of cutting-edge technologies dedicated to the study of proteins and their interactions in 35+ organisms and any research thematic. We offer three main lines of services: • Interactions Discovery: ULTImate Y2H™ to discover novel protein-protein interactions in various tissues/cell types o Several adapted versions allow to identify interactions with transmembrane proteins, DNA and RNA o Associated services: Interaction Domain Mapping, Low binders, super binders • Drug Discovery Services (Adapted from ULTImate Y2H) o Target deconvolution: ULTImate YChemH™ to identify on- and off-targets of small bioactive molecules - mechanism of action, polypharmacology, drug repositioning, prediction of toxicity o Protein-protein interactions induced by molecular glues (protein stabilization, targeted protein degradation) • Nanobody® (or Synthetic Antibodies, VHH) to select and validate high-affinity single-domain antibodies (Hybribody™) - for IF, ELISA, high-resolution microscopy, video-microscopy, target inhibition applications but also for diagnosis and therapeutic purposes Our optimized screening platform in yeast enables the identification of the protein partners of proteins, DNA sequences, RNA and small molecules of therapeutic interest. Highly complex protein domain libraries, prepared from any cell type or tissue, are screened to saturation to identify partners and their interacting domains using a transcriptional read-out. Sophisticated bioinformatics analysis allows to attribute confidence scores to each interaction. With more than 3,200 academic and industrial customers from over 40 countries, Hybrigenics Services is internationally recognized. Among our services, our yeast two-hybrid screening technology, ULTImate Y2H, is extensively used in many research projects. The results obtained at Hybrigenics have been quoted in more than 480 scientific publications to date. Hybribody offers single-domain antibody selection and validation services. We handle the in vitro selection of antibodies against your protein from a fully synthetic humanized VHH library by an optimized Phage Display technology. VHHs have the advantages of being very small (15 kDa), affine and stable molecules. We validate the selected VHHs for in vitro and in vivo applications (ELISA, IF, Intrabody…). We can also fuse the VHH with Fc fragments from the species of your choice to deliver fully functional recombinant antibodies. In addition, Hybrigenics Services provides optimization of nanobodies coming from the Llama using yeast display technology. Nanobody® is a trademark of Ablynx.

153 avenue d’Italie, 75013 Paris, FranceImmunodiagnostic Systems (IDS) develops immunoassays and automated immunoanalyser technologies for use in clinical and research laboratories.

60 Rue Notre Dame-des-Champs Paris, 75006 FranceIMSTAR draws on its in-house expertise in biomodelling and statistics, cell biology and bioinformatics as wells on a network of experts in the fields of biology, cell biology, pathology, oncology, neurosciences, dermatopathology, cytogenetics, molecular genetics, and molecular medicine.

Paris, Île-de-France FranceIMSTAR draws on its in-house expertise in biomodelling and statistics, cell biology and bioinformatics as wells on a network of experts in the fields of biology, cell biology, pathology, oncology, neurosciences, dermatopathology, cytogenetics, molecular genetics, and molecular medicine.

26 Avenue Christian Doppler E4 Bldg Bailly-Romainvilliers, Marne-la-Vallée, 77700 FranceInnoBioMil, a French company specializing in the manufacturing of premium-quality cell culture media, feeds, and ISO-certified CMO services for the biotech and biopharmaceutical research sectors. At InnoBioMil, we offer customizable media development tailored to specific cell clones and recombinant proteins, all designed to meet the unique requirements of projects.

4 rue Pierre Fontaine Evry-Courcouronnes, Ile-De-France, 91000 FranceINNOVHEM is a french startup focused on pahtologies involving red blood cells. We have developed a unique method for single cell quantification of fetal hemoglobin and new biomarkers aiming to track hemolysis in different conditions. These biomarkers are proposed to assess the efficacy of treatments from research to clinical stage of development.

92 avenue du général de Gaulle Créteil, Ile-De-France, 94000 FranceINNOVHEM is a french startup focused on pahtologies involving red blood cells. We have developed a unique method for single cell quantification of fetal hemoglobin and new biomarkers aiming to track hemolysis in different conditions. These biomarkers are proposed to assess the efficacy of treatments from research to clinical stage of development.

251 Rue Saint-Jacques Paris, Île-de-France, 75005 FranceAs part of its service delivery business, Inovarion develops and provides tailor-made services in life sciences: 1. Research expertise project missions 2. Missions of expertise in the pooling of technical services Furthermore, Inovarion has a recognized expertise in the field of biosensors.

147 Rue de l' Université Paris, Île-de-France, 75007 FranceNotre mission est de mettre à la disposition de la communauté scientifique des compétences et des outils autour du modèle expérimental porcin comme espèce cible ou comme organisme modèle.

101 rue de Tolbiac Paris, 75654 FranceThe Paoli-Calmettes Institute (IPC) is a comprehensive cancer center and a member of the Unicancer group, governed by the Public Health Code. The IPC is a Private Healthcare Facility of Public Interest (ESPIC).

Paris FranceInsideBiotec consulting is a French consulting firm specialized in supporting biotech companies in developing their business activities (including product and service-based offers) through marketing & communication services. Whether your company is at an early stage of its development (from project design in incubation to its first years of growth) or an already well-established structure, we can support you with marketing & communication services to answer your specific challenges.

110 Av. de Bures Bures-sur-Yvette, 91440 FranceThe Institut Curie provides to researcher technological platforms for scientific imaging, genomics, proteomics and bioinformatics. Facilites improve diagnosis, treatment of cancer and follow-up of patients. Platforms include: * Chemical Library * Next Generation Sequencing * Synthetic Genetic Array (SGA) * Genomics * Mass Spectrometry and Proteomics Facility * Therapeutic Antobodies (TAB-IP) and Recombinant Antibodies * Protein Expression and Purification Core Facility * Reverse Phase Protein Array * "Cell & Tissue Imaging":/wares/make-a-request/quote_groups/new?name=Institut+Curie+-+Cell+and+Tissue+Imaging+Platform+%28PICT%29&provider=Institut+Curie+-+Cell+and+Tissue+Imaging+Platform+%28PICT%29 * Biophenics * Flow CYtometry * Cytometry: Cell Sorting & Analysis * Experimental Radiotherapy * In Vivo Experiments * Pre-clinical Investigation Laboratory (LIP) * Bioinformatics Platform

26 rue d’Ulm Paris , 75248 FranceThe Institut Curie provides to researcher technological platforms for scientific imaging, genomics, proteomics and bioinformatics. Facilites improve diagnosis, treatment of cancer and follow-up of patients. Platforms include: * Chemical Library * Next Generation Sequencing * Synthetic Genetic Array (SGA) * Genomics * Mass Spectrometry and Proteomics Facility * Therapeutic Antobodies (TAB-IP) and Recombinant Antibodies * Protein Expression and Purification Core Facility * Reverse Phase Protein Array * "Cell & Tissue Imaging":/wares/make-a-request/quote_groups/new?name=Institut+Curie+-+Cell+and+Tissue+Imaging+Platform+%28PICT%29&provider=Institut+Curie+-+Cell+and+Tissue+Imaging+Platform+%28PICT%29 * Biophenics * Flow CYtometry * Cytometry: Cell Sorting & Analysis * Experimental Radiotherapy * In Vivo Experiments * Pre-clinical Investigation Laboratory (LIP) * Bioinformatics Platform

26 rue d’Ulm Paris Cedex 05, 75248The Institut Curie Bioinformatics platform is composed of thirty bioinformaticians, biostatisticians and software engineers who offer a multidisciplinary expertise to support the biotechnological platforms, the research units and the hospital in their daily activities. Our skills range from statistical data analysis, data management, software development and high performance computing. We have five main missions: (1) knowledge and data integration, (2) collaborative support to biologists or clinicians for bioinformatics and biostatistics data analysis, (3) delivering advices and training in biostatistics and bioinformatics, (4) support to high performance computing and (5) coordination of bioinformatics activities within Institut Curie.

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe Biomaging Cell and Tissue Core Facility of the Institut Curie (PICT-IBiSA) gathers highly sophisticated equipments and up to date technologies in advanced microscopy. Its main aim is to provide research groups from inside and outside the Institut Curie with a workflow of state to the art imaging approaches to study at different scales and with complementary methods molecules, organelles, cells, whole organisms and tissues in normal and pathological states. Our Imaging Core Facility gathers equipment in advanced light microscopy (Optogenetics and Active Illumination setups, d-STORM, high resolution SIM, LLSM; multiple MP(NLO), Multi-Angle TIRFM…), electron microscopy (immunololabelling, cellular EM, High-pressure freezing, CryoEM, room temperature and cryo-EM tomography, STEM and EFTEM 2D/3D, chemical mapping) and NanoSIMS, and correlative light-electron microscopy.

26 rue d’Ulm Paris Cedex 05, 75248 FranceBioPhenics facility specializes in chemical biology as it relates drug discovery, biological probe discovery and phenotypic characterization of small-molecule effects (siRNAs and chemical compounds) on cellular systems. The facility provides basic and applied research teams with the technical resources and expertise needed to carry out high-content screens. The facility has enabled screening projects for different research groups in Europe, most of them located in cancer centers, aiming to benefit from the platform capabilities for identifying both the genes and pathways that mediate disease states and novel compounds that modulate these pathways. BioPhenics operates with a philosophy of collaboration, rather than fee-for-service. These screens can be carried out using small molecule or siRNA libraries curated by BioPhenics or with custom libraries developed by researchers.

26 rue d’Ulm Paris Cedex 05, 75248 FranceFlow cytometry measures the fluorescence or light diffraction of a large number of particles at high speed, such as cells, beads, bacteria, yeast, or organelles. At Institut Curie, flow cytometry is used mainly to quantify multiple markers on cells, with the option of simultaneously sorting multiple sub-populations of interest. The primary advantage of flow cytometry is how quickly it produces data for a very large number of cells, allowing for complex and/or rare sub-populations of cells to be analyzed and sorted so that they can then be cultured or analyzed with molecular biology tools. The cells in suspension may be simultaneously marked with 11 fluorochromes, each identifying a molecule of interest. The marked cells flow past a laser and, for each cell, the fluorescence intensity is quantified for each fluorochrome.
Fluorescent probes can be used to detect various parameters such as membrane potential, pH, or cell cycle (proliferation, apoptosis, etc). The flow cytometry platform performs cell sorting, and also trains people to independently use high-speed multiparameter cytometers and the supporting software to acquire and analyze data.

Paris, Île-de-France FranceComputational Systems Biology of Cancer group exists in the Bioinformatics Unit of Institut Curie since the end of 2004. Now it consists of several permanent researchers, postdocs and PhD students.

26 rue d’Ulm Paris Cedex 05, 75248 In the last few years, significant advances have been made in radiation therapy techniques (complex irradiation schemes, higher dose rates, new radiation types, wider range of indications etc.), but not all these advances have been validated in preclinical studies. The challenge lies in the complexity to apply these novel radiation treatments to cellular model or small animals. A platform providing support through interdisciplinary skills in experimental radiotherapy was therefore required, to improve the development of radiotherapy techniques.

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe flow cytometry core facility of the Institut Curie in Orsay is available for Institut Curie research teams, external academic and to industry. Flow cytometry is generally used for a multiparametric analysis of individual cells in suspension, with the possibility of subsequently sorting subpopulations of interest. The cells in suspension may be simultaneously marked with many fluorochromes, each identifying a molecule of interest. The marked cells flow pass through a laser and, for each cell, the fluorescence intensity is quantified for each fluorochrome. Fluorescent probes can be used to detect different parameters such as: cell cycle, proliferation, apoptosis, pH changes and calcium flux. The purpose of the flow cytometry core facility is to sort cells for users, and to train facility users on the self-service cytometers and related software for data acquisition and analysis.

26 rue d’Ulm, Paris Cedex 05, 75248 FranceThe Institut Curie Research Center provides a spectrum of facility areas for housing a variety of different Vertebrate models, allowing the Institut Curie research community access to advanced technical expertise.

26 rue d’Ulm Paris Cedex 05, 75248 The treatment of cancer is continually improving due to increasing knowledge in oncogenesis and the development of new targeted compounds. Many candidate compounds for clinical trials are therefore generated each year.

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe Protein Production and Purification Facility is a core service and resource to overcome the major bottleneck in recombinant protein expression and purification. Mainly we provide advice and active support for researchers scientific community in the use of the procaryotic and eukaryotic expression system for recombinant protein production. The facility offers equipment and materials required for the expression of protein in bacterial, Yeast, insect (baculovirus) and mammalian cell. We can execute the complete cloning, expression, scale-up and purification process or specific tasks within the project. We have optimized different expressions vectors in combination with various bacterial strains, yeast strain, insect strain and mammalian cell for specific expression of different types of proteins.

26 rue d’Ulm Cedex 05, Paris, 75248 FranceReverse Phase protein Arrays represent an innovative technology that allows studying protein expression levels and the activation status of cell signalling pathways. It combines high throughput analysis with minimal sample consumption. Using a dedicated arrayer, only 1 ng of proteins extracted from tissues or cell lines are printed onto nitrocellulose covered microscope slides (arrays). Proteins of interest are then quantified using highly specific primary antibodies. Up to one thousand samples can be analysed simultaneously on the same array. We systematically print serial dilutions and replicates for all samples, making the technology highly robust and quantitative. Our platform has validated almost 600 primary antibodies for RPPA labelling so far, among which almost 150 antibodies against phosphorylated proteins. This panel of antibodies covers the majority of cell signalling pathways. For each project, the project leader selects the antibodies of interest for his/her project among the validated antibodies. New antibodies are continuously being tested in the context of ongoing scientific projects.

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe group uses its own fully synthetic phage display library of humanized llama recombinant single domain antibody that can provide high affinity binders without animal immunization. The library contains 3.109 independent nanobodies.

46, Rue d’Ulm 75005 Paris, France

47 Boulevard de l'Hôpital Paris-13E-Arrondissement, Île-de-France, 75013 FranceThe Institut du Cerveau et de la Moelle épinière – ICM (Brain & Spine Institute) – is an international brain and spinal cord research center whose innovative concept and structure make it the only institute of its kind in the world. The ICM brings patients, doctors and researchers together with the aim of rapidly develop treatments for disorders of the nervous system and enable patients to benefit from them as quickly as possible. The best scientists from all backgrounds and countries come together at the Institute to perform leading-edge research in this area. To help researchers advance in their work and give patients tangible reasons for hope, we must all play a role: government agencies, corporate actors and individuals. No one can afford to idly stand by, because this fight is vital to every one of us.

25-28, rue du Docteur-Roux Paris Cedex 15, 75724 FranceThe Institut Pasteur was opened on November 14, 1888 thanks to Louis Pasteur’s international appeal for funds. He now had the facilities to extend vaccination against rabies, continue research on infectious diseases and share the resulting knowledge. The Institut Pasteur is a private, non-profit foundation. Its mission is to help prevent and treat diseases, mainly those of infectious origin, through research, teaching, and public health initiatives.

28 Rue du Docteur Roux, Paris, Île-de-France 75015, FRThe Institut Pasteur was opened on November 14, 1888 thanks to Louis Pasteur’s international appeal for funds. He now had the facilities to extend vaccination against rabies, continue research on infectious diseases and share the resulting knowledge. The Institut Pasteur is a private, non-profit foundation. Its mission is to help prevent and treat diseases, mainly those of infectious origin, through research, teaching, and public health initiatives.

28 Rue du Docteur Roux 75015, Paris France

1 chemin du saulxier Bâtiment 4b Longjumeau, 91160 FranceThe IntegraCell platform carry out high quality functional metabolism exploration analyses of several central cell metabolisms, namely oxidative stress and mitochondria energy production, on your preferred biological model (cell, animal, …). It uses high throughput, muti-parametric, non-radioactive, quantitative readouts technology.

5 Rue Henri Desbruères Genopole Campus 1 - Genavenir 8 Évry-Courcouronnes, Île-de-France, 91030 FranceIntegraGen offers innovative next-generation sequencing services and customized bioinformatics and biostatistics tools to analyze genomic data. Established in 2000, IntegraGen (member of the OncoDNA Group) specializes in the genomic analysis of all nucleic acids, with a particular focus on cancer and rare genetic diseases. Backed by highly experienced and qualified teams, IntegraGen is a leading player in DNA and RNA sequencing services as well as genomic data interpretation software development. The company runs one of the largest NGS labs in France and for services for most research institutes of excellence as well as private and public institutions and companies across Europe. IntegraGen laboratory was granted the CAP (college of American Pathologists) accreditation in December 2023 and became CLIA certified in January 2024. The company's vision and mission is to make personalized medicine gigantic progresses available to researchers, clinicians and eventually patients, and positions itself as a leading provider of comprehensive nucleic acid information, empowering researchers and healthcare providers to unlock breakthroughs in cancer care as well as inherited & infectious diseases.

1 rue de l'internationale, Evry, France 91000IntegraGen offers innovative next-generation sequencing services and customized bioinformatics and biostatistics tools to analyze genomic data. Established in 2000, IntegraGen (member of the OncoDNA Group) specializes in the genomic analysis of all nucleic acids, with a particular focus on cancer and rare genetic diseases. Backed by highly experienced and qualified teams, IntegraGen is a leading player in DNA and RNA sequencing services as well as genomic data interpretation software development. The company runs one of the largest NGS labs in France and for services for most research institutes of excellence as well as private and public institutions and companies across Europe. IntegraGen laboratory was granted the CAP (college of American Pathologists) accreditation in December 2023 and became CLIA certified in January 2024. The company's vision and mission is to make personalized medicine gigantic progresses available to researchers, clinicians and eventually patients, and positions itself as a leading provider of comprehensive nucleic acid information, empowering researchers and healthcare providers to unlock breakthroughs in cancer care as well as inherited & infectious diseases.

Incubateur de l'Institut de la Vision, Bâtiment B1/B2 74 rue du Faubourg Saint Antoine Paris, 75012 FranceIris Pharma is a world-leading Contract Research Organization (CRO) offering preclinical ophthalmology research services. Iris Pharma works hand-in-hand with customers and has helped bring more than 70 ocular drugs and medical devices to international markets to date. The company is able to do this as efficiently as possible by maintaining a global view of the development process and by bringing personalized advice. Iris Pharma indeed addresses all ophthalmology challenges by offering programs and study designs that perfectly suit the needs of customers: therapeutic value assessment, full preclinical regulatory package, product value creation or à la carte studies. Compliance with GLP requirements; CIR agreement.

12 quai Henri IV 75194 Paris Cedex 04 FranceIsochem offers custom chemical synthesis and manufacturing services.

Evry, FranceIstem provides screening, pathology models, therapeutic molecule development, genomics, stem cell services, and high throughput screening.

4 route de la Noue
 91190 Gif-sur-Yvette – FranceKayentis offers a various range of software, medical solutions and services electronic patient reported outcome for facilitating your job in clinical data management.

74 rue du fauboug Saint-Antoine Paris, 75012 FranceKeen Eye is an AI platform company aiming at bringing decision-support and image analysis services for accelerating drug development from translational research to clinical phases and improving cancer diagnosis and therapies. Keen Eye brings accurate, standardized and undiscovered tissue insights through its cloud-based computational pathology platform which optimize users’ process and scale up their capacity.

20 Rue Clément Bayard Levallois-Perret, Île-de-France, 92300 France

6 rue Paul Baudry Paris, France, 75008 FranceKHiMii develops innovative reactors for flow chemistry, with outstanding performances at extreme temperature or pressure and with a strong focus on the industrialization at large scale. As an example, our equipment delivers strong performances on hydrogenation, with or without heterogeneous catalyst. Our equipment is available from the kilo-lab to the thousand tone scales. This equipment is available for technical studies in our partner lab or can be leased or purchased. Our reactors are made in France by a breakthrough welding technology.

4 rue Yvette Cauchois Gif-sur-Yvette, 91190 FranceKimialys offers ready-to-use gold biochips (SPR) and nanoparticles (LFA) coated with an innovative and patented surface chemistry, improving the sensitivity of sensors in any type of biological matrix.

8 rue Méchain Paris, 75014 FranceKimialys offers ready-to-use gold biochips (SPR) and nanoparticles (LFA) coated with an innovative and patented surface chemistry, improving the sensitivity of sensors in any type of biological matrix.

28 Rue Jacques Ibert Levallois-Perret, 92300 France

Cité InternationaleL2D Services provides consulting and operational management of services ranging from preclinical development to manufacturing.

Paris, Île-de-France FranceL2D Services provides consulting and operational management of services ranging from preclinical development to manufacturing.

1 chemin de Saulxier Longjumeau, 91160 FranceCustom-made studies in claims substantiation for cosmetic and pharmaceutical companies. Created in 1998, BIO-EC is a research center dedicated to cosmetic and dermatological professionals. Our goal is to answer all kind of needs in claims substantiation. Several methods to assess products efficacy : animal-free efficacy testing for (dermo)cosmetics, clinical studies on volunteers, gene expression analysis, percutaneous absorption, RAMAN spectroscopy, topography.

1 Chemin de Saulxier 91160 Longjumeau FranceCustom-made studies in claims substantiation for cosmetic and pharmaceutical companies. Created in 1998, BIO-EC is a research center dedicated to cosmetic and dermatological professionals. Our goal is to answer all kind of needs in claims substantiation. Several methods to assess products efficacy : animal-free efficacy testing for (dermo)cosmetics, clinical studies on volunteers, gene expression analysis, percutaneous absorption, RAMAN spectroscopy, topography.

Lorris, Centre-Val de Loire, 45260 FranceLaboratoire Cat provides blister packaging, sterilization, and secondary packaging of drugs.

20 rue Louis-Charles Vernin 77190 Dammarie-Les-Lys FranceLaboratoires Galéniques Vernin specializes in manufacturing pharmaceutical and health industry products.

3, avenue des TropiquesLFB Group provides therapeutic proteins, plasma-derived medicinal products, and biological drugs. LFB offers cell line development, preclinical process development, and clinical manufacturing services through its biomanufacturing division.

12 Avenue de Scandinavie Courtaboeuf Cedex, Île-de-France, 91967 FranceLFB Group provides therapeutic proteins, plasma-derived medicinal products, and biological drugs. LFB offers cell line development, preclinical process development, and clinical manufacturing services through its biomanufacturing division.

VALLEE SUD BIO PARC 28 rue de la redoute Fontenay-aux-Roses, IDF, 92260 FranceLife and Soft is a bioinformatics company We offer bioinformatics and biostatistics services. We have a sequencing platform in France covering Illumina and Nanopore sequencing but also scRNA-seq. Our packaged offer in genomics covers DNA, microbiome, transcriptomics and methylation analysis. If you have sequencing data to analyze, our apps: Nanobiome, Onco Lifepipe and Nanoware Cloud hosted will give you a wide range of analysis (16S, Full 16S, Shotgun, targeted sequencing, ARTIC, COVIDseq...)

CEA IDMIT 18 route du Panorama Fontenay-aux-roses, IDF, 92260 FranceLife and Soft is a bioinformatics company We offer bioinformatics and biostatistics services. We have a sequencing platform in France covering Illumina and Nanopore sequencing but also scRNA-seq. Our packaged offer in genomics covers DNA, microbiome, transcriptomics and methylation analysis. If you have sequencing data to analyze, our apps: Nanobiome, Onco Lifepipe and Nanoware Cloud hosted will give you a wide range of analysis (16S, Full 16S, Shotgun, targeted sequencing, ARTIC, COVIDseq...)

5 avenue d'Italie avenue d'Italie Paris, Paris, 75013 FranceLinical is a public, mid-sized Contract Research Organization headquartered in Japan with a significant presence across all major markets including North America, Europe, and Asia-Pacific. Linical provides the full spectrum of drug development services from early stage to large-scale, multinational studies. Our areas of focus include Phase I-IV studies in oncology, neurology & psychiatry, immunology & vaccine, and endocrinology & metabolic diseases.

15-17 rue Vulpian Paris, 75013 FranceLinical is a public, mid-sized Contract Research Organization headquartered in Japan with a significant presence across all major markets including North America, Europe, and Asia-Pacific. Linical provides the full spectrum of drug development services from early stage to large-scale, multinational studies. Our areas of focus include Phase I-IV studies in oncology, neurology & psychiatry, immunology & vaccine, and endocrinology & metabolic diseases.

29 avenue Roger Hennequin Trappes , 78197 FranceA public industrial and commercial institution (EPIC designation), LNE has been placed under the trusteeship of the French Ministry for the Economy and Finance with oversight for Industry. Relying on an excellent scientific and technical skill set, LNE's research efforts have formed the basis of multiple applications: calibration, testing, certification, etc. Renowned for its expertise both in France and abroad, LNE performs measurements that serve the economy and society.

41, Rue MartreL'Oreal EpiSkin develops and manufactures in vitro skin models for the application of efficacy and safety testing.

21 rue Jean Rostand 91400 ORSAY, ESSONNE, 91400 FranceLPS-BioSciences is a biotechnical company that focuses on the research and development of vaccines, diagnostics and endotoxins quantification and removal.

Bâtiment 440, Rue des Adèles 91400 ORSAY, ESSONNE, 91400 FranceLPS-BioSciences is a biotechnical company that focuses on the research and development of vaccines, diagnostics and endotoxins quantification and removal.

61 rue du mont-cenis Paris, Idf, 75018 France

1 Parvis Notre-Dame Pl. Jean-Paul II Paris, 75004 FranceMAbSilico is a TechBio company developing and providing AI-based solutions for antibody drug design and discovery. We help biotech and pharma companies to leverage antibody discovery risks by providing computational candidates in days which are designed and characterized in silico and validated with state-of-the-art biological technologies. While MAbSilico combines 3D modeling, interaction simulation and linear sequences analysis, the antibody drug candidates are defined through their epitope, affinity, off-target risk, cross-species reactivity and developability assessment to be ready for biological activity evaluation. Using NLP technologies we gather information about antibodies and their target in different databases to ensure competitive landscape analysis and the freedom to operate of the computationally designed antibodies candidates.

Avenue 36-42 Marc Sangnier 92390 VILLENEUVE LA GARENNE FranceMACORS manufactures low dose products, bags and hormonal products.

161 Rue de la belle Etoile Roissy, 95700 FranceMacrogen Europe is a leading sequencing provider. We provide DNA and RNA sequencing for all types of samples using technology provided by our partnerships Illumina, PacBio, and Oxford Nanopore Technologies among others. However, what is most important for us is to provide high-quality data together with committed customer service. From assisting you in sending samples to us, a personal following of your project, and data delivery.

2, rue du Belvédère, 91120 Palaiseau, FranceMedit provides CRO consulting, hit discovery, protein vaccine design, and drug design.

4 rue Pierre Fontaine 91058 Evry cedex FranceMETAFORA biosystems is a biotechnology company dedicated to developing the use of RBDs which are ligands of nutrient transporters.

4 rue Pierre Fontaine Evry cedex, 91058 FranceMETAFORA biosystems is a biotechnology company dedicated to developing the use of RBDs which are ligands of nutrient transporters.

67 rue Saint-Jacques Paris, 75005 FranceMETHYS Dx offers digital PCR testing services, based on a portfolio of unique, cancer-specific molecular signatures, especially pertinent for liquid biopsy approaches. Our tests are based on agnostic detection of circulating tumor DNA in liquid biopsy samples (no need to access to tumor tissue). These highly performing tests can be carried out quickly, and allow dynamic monitoring of patients, ensuring fast access to crucial information on cancer evolution.

Paris, Île-de-France FranceMicroBioChips provides protein array, biomarker, and screening services.

Faculté de Médecine 8, rue du Général Sarrail Créteil, 94000 FranceMitologics S.A.S. is a biotechnology company specialized in detection of mitochondrial alterations. The company has developped technological platforms dedicated to compounds screening to identify compounds toxicity (DILI, cardio-toxicity) or efficacy (Oncology, Neuro-, Cardio-protection...). Among them, respiratory chain activity is measured in cultured cells or isolated mitochondria using Seahorse XFe-96 analyzer or soluble probes. Mitologics has expertise in developing customized bioassays for the validation and release of biotherapeutic products. Since 2009, Mitologics has performed more than 300 R&D studies for pharmaceutical companies and biotech, as well as cosmetic and agro-chemistry companies especially in Europe, the United States, and Asia.

102 Avenue Gaston Roussel ROMAINVILLE , 93230 FranceMitologics S.A.S. is a biotechnology company specialized in detection of mitochondrial alterations. The company has developped technological platforms dedicated to compounds screening to identify compounds toxicity (DILI, cardio-toxicity) or efficacy (Oncology, Neuro-, Cardio-protection...). Among them, respiratory chain activity is measured in cultured cells or isolated mitochondria using Seahorse XFe-96 analyzer or soluble probes. Mitologics has expertise in developing customized bioassays for the validation and release of biotherapeutic products. Since 2009, Mitologics has performed more than 300 R&D studies for pharmaceutical companies and biotech, as well as cosmetic and agro-chemistry companies especially in Europe, the United States, and Asia.

Le Dorian 2B, 1rst floor 172, rue de Charonne Paris, 75011 FranceMitologics S.A.S. is a biotechnology company specialized in detection of mitochondrial alterations. The company has developped technological platforms dedicated to compounds screening to identify compounds toxicity (DILI, cardio-toxicity) or efficacy (Oncology, Neuro-, Cardio-protection...). Among them, respiratory chain activity is measured in cultured cells or isolated mitochondria using Seahorse XFe-96 analyzer or soluble probes. Mitologics has expertise in developing customized bioassays for the validation and release of biotherapeutic products. Since 2009, Mitologics has performed more than 300 R&D studies for pharmaceutical companies and biotech, as well as cosmetic and agro-chemistry companies especially in Europe, the United States, and Asia.

Le Dorian B2 172 rue de Charonne Paris, 75011 FranceMitologics S.A.S. is a biotechnology company specialized in detection of mitochondrial alterations. The company has developped technological platforms dedicated to compounds screening to identify compounds toxicity (DILI, cardio-toxicity) or efficacy (Oncology, Neuro-, Cardio-protection...). Among them, respiratory chain activity is measured in cultured cells or isolated mitochondria using Seahorse XFe-96 analyzer or soluble probes. Mitologics has expertise in developing customized bioassays for the validation and release of biotherapeutic products. Since 2009, Mitologics has performed more than 300 R&D studies for pharmaceutical companies and biotech, as well as cosmetic and agro-chemistry companies especially in Europe, the United States, and Asia.

60, route de SartrouvilleNew Brunswick Scientific offers optimization, cell expertise, computer-controlled strategies, and media formulation.

23, Boulevard de L'EuropeNewLab provides oncology and animal management software.

19 Rue Malesherbes Madeleine 75008 ParisNexus Oncology offers data management, site selection, project management, and drug development consultancy to support studies in oncology.

Évry, Île-de-France FranceNOKAD provides functional knockout aniamls, functional characterization, mammalian adenoviral overexpression, and antibodies against low antigenic protein.

4 rue Pierre Fontaine, Evry 91000, FranceNOKAD provides functional knockout aniamls, functional characterization, mammalian adenoviral overexpression, and antibodies against low antigenic protein.

Paris, FranceNoldus Information Technology develops software and technology in the application of tracking animal behavior.

102 Avenue Gaston Roussel Romainville, 93230 FranceNovalix is a premier contract research organization, dedicated to improving the critical early stages of drug discovery by combining exceptional scientific talent and exclusive technology with a comprehensive portfolio of world-class chemistry, biophysics and pharmacology capabilities. We apply our exceptional scientific talent and exclusive resources across our platform to improve the odds of success at each critical pre-clinical stage. The better the science, the better the outcomes. Our capabilities include: - Medicinal chemistry - Cheminformatics - Synthetic chemistry - Process chemistry and scale-up - Biophysics: NMR, MS, SPR - Protein production with expertise in GPCRs - Structural biology: Cryo-EM, protein x-ray crystallography and NMR - in vitro pharmacology - in vivo pharmacology - Translational science - Biobanking - Histology - ADME-DMPK and pre-formulation Experts in diverse modalities: small molecules, biologics (mAbs, ADCs), PROTACs. Therapeutic areas: oncology, immuno-inflammation, infectious diseases, fibrosis, kidney, osteoarthritis, metabolic disorders. Our facilities are located in France and Tunisia. We operate business representative offices in the United States, Japan and Tunisia.

81 rue de Sevres, 92100, Boulogne-BillancourtNovasyn Organics specializes in multi-step synthesis of substituted pyridine compounds.

243, route de Sandrancourt F-78520 Saint Martin La Garenne, FranceNovotec provides ECM analysis, cell cultures, image analysis, culture supernatant dosages, and cellular viability.

Saint-Martin-la-Garenne, Île-de-France FranceNovotec provides ECM analysis, cell cultures, image analysis, culture supernatant dosages, and cellular viability.

111, Bd Duhamel de MonceauNucleosyn is expert in DNA & RNA synthesis reagents, synthetic lipids from mg to kgs and stable isotope labelled molecules. We have particular expertise in the specialized chemistry, purification and analytical techniques required to synthesize these challenging compounds. Nucleosyn’s business has been built around its unique chemistry skills and experience in custom synthesis. Among these, Nuleosyn offers an extensive line of standard phosphoramidites, RNA phosphoramidites, specialty amidites and modifiers, solid supports CPG, reagents and solvents for a wide variety of instruments. Nucleosyn offers in its catalog most of the lipids that could be used for transfection of nucleic acids and we have developed an expertise in the synthesis of cationic ionizable lipids (DLin-MC3-DMA, C12-200…), cationic permanently charged lipids (DOTAP, DOTMA…), and also other structural and/or helper lipids (DSPC, DOPE, Cholesterol derivatives…). Nucleosyn provides also Custom Stable Isotope (2H, 13C, 15N) Compounds to support projects dedicated to : bioanalytics, Omics research, Molecular Imaging, Biomarker discovery.

12/14 Rond Point des Champs Elysées, 75008 Paris, FranceNumoda offers support and consultation for companies moving from clinical development to marketing partners.

25-27 Avenue du Quebec BP 27627 Villebon-sur-Yvette , 91140 FranceDeveloping a new therapeutic involves critical decisions made under pressure. As programs move from validated candidates toward the clinic, the quality, relevance, and interpretation of preclinical data become decisive. At this stage, generating data alone is not enough. What matters is whether the evidence supports confident progression toward clinical development. Oncodesign Services supports biopharma and biotechnology teams navigating this complexity through advanced preclinical pharmacology and translational research services. We specialize in preclinical development programs in targeted radiotherapy, oncology, immuno-oncology, and inflammation and autoimmune diseases, with a focus on the translational phase of drug development. In targeted radiotherapy, we support programs from early candidate through IND-enabling studies, addressing challenges including radionuclide supply, biodistribution imaging, dosing strategy, and translational relevance. Our preclinical pharmacology work spans oncology, immuno-oncology, and immune-mediated inflammatory diseases, with studies designed around disease biology, proof of concept, and mechanism of action. Imaging approaches are integrated where appropriate to support longitudinal assessment of pharmacological effects and biodistribution, while model selection and development are tailored to the biological and translational questions driving each study. Experience across preclinical development includes: - 30+ years in preclinical oncology research - 20+ years in preclinical imaging - 10+ years in inflammatory disease research - 10+ years in radiopharmaceutical development Our facilities are AAALAC-accredited, reflecting internationally recognized standards for the humane and responsible use of animals in research.

25-27 Avenue du Québec Villebon-sur-Yvette , 91140 FranceDeveloping a new therapeutic involves critical decisions made under pressure. As programs move from validated candidates toward the clinic, the quality, relevance, and interpretation of preclinical data become decisive. At this stage, generating data alone is not enough. What matters is whether the evidence supports confident progression toward clinical development. Oncodesign Services supports biopharma and biotechnology teams navigating this complexity through advanced preclinical pharmacology and translational research services. We specialize in preclinical development programs in targeted radiotherapy, oncology, immuno-oncology, and inflammation and autoimmune diseases, with a focus on the translational phase of drug development. In targeted radiotherapy, we support programs from early candidate through IND-enabling studies, addressing challenges including radionuclide supply, biodistribution imaging, dosing strategy, and translational relevance. Our preclinical pharmacology work spans oncology, immuno-oncology, and immune-mediated inflammatory diseases, with studies designed around disease biology, proof of concept, and mechanism of action. Imaging approaches are integrated where appropriate to support longitudinal assessment of pharmacological effects and biodistribution, while model selection and development are tailored to the biological and translational questions driving each study. Experience across preclinical development includes: - 30+ years in preclinical oncology research - 20+ years in preclinical imaging - 10+ years in inflammatory disease research - 10+ years in radiopharmaceutical development Our facilities are AAALAC-accredited, reflecting internationally recognized standards for the humane and responsible use of animals in research.

18, route du Panorama BP 6 Fontenay-aux-Roses cedex, 92265 FranceDeveloping a new therapeutic involves critical decisions made under pressure. As programs move from validated candidates toward the clinic, the quality, relevance, and interpretation of preclinical data become decisive. At this stage, generating data alone is not enough. What matters is whether the evidence supports confident progression toward clinical development. Oncodesign Services supports biopharma and biotechnology teams navigating this complexity through advanced preclinical pharmacology and translational research services. We specialize in preclinical development programs in targeted radiotherapy, oncology, immuno-oncology, and inflammation and autoimmune diseases, with a focus on the translational phase of drug development. In targeted radiotherapy, we support programs from early candidate through IND-enabling studies, addressing challenges including radionuclide supply, biodistribution imaging, dosing strategy, and translational relevance. Our preclinical pharmacology work spans oncology, immuno-oncology, and immune-mediated inflammatory diseases, with studies designed around disease biology, proof of concept, and mechanism of action. Imaging approaches are integrated where appropriate to support longitudinal assessment of pharmacological effects and biodistribution, while model selection and development are tailored to the biological and translational questions driving each study. Experience across preclinical development includes: - 30+ years in preclinical oncology research - 20+ years in preclinical imaging - 10+ years in inflammatory disease research - 10+ years in radiopharmaceutical development Our facilities are AAALAC-accredited, reflecting internationally recognized standards for the humane and responsible use of animals in research.

8 Rue Maria Helena Vieira Da Silva Paris 14e Arrondissement, Île-de-France, 75014 FranceOne Biosciences is a cutting-edge biotech company specializing in precision oncology through the integration of single-cell technologies and AI-driven insights. We analyze tumor ecosystems to provide actionable data for clinicians and pharmaceutical companies, enabling optimized treatment decisions, patient selection for clinical trials, and the identification of novel therapeutic targets.

1 rue Amedee Gordini PA Gomberville Magny Les Hameaux, 78114 FranceORGA-LINK is an independant CRO which proposes efficient services of Research and Development in Organic Synthesis on the scale from miligrams to kilograms. ORGA-LINK services also include extraction of natural products and analysis as well as the development of new compounds. ORGA-LINK proposes services in organic chemistry based on quality, flexibility and efficiency tailored to your needs with optimized costs. As multi-skilled chemists, we can realize every type of chemistry, from pharmaceuticals to peptide chemistry to inorganic chemistry with particularly strong expertise in the field of heterocyclic chemistry. TO KEEP YOUR TEAMS FOCUSED ON SUBJECTS OF HIGHER ADDED VALUE AND SAVE YOU BOTH TIME AND MONEY REDUCING YOUR COSTS OF SYNTHESIS : OUTSOURCE A PART OF YOUR R&D WORK. ORGA-LINK can meet your needs in term of : • Organic synthesis : multi-stage synthesis from the mg to multi-kg of derivatives, impurities, products, targets / leads and analogues • Classical or original synthesis: high pressure reaction, photosensitive (inactinic light), stable isotopic labelling (D, 13C, 15N) • R&D under contract in organic chemistry • Structural analysis, extraction • Quantitative analysis, dosage • Sourcing of compounds • Database and literature searching

Rond-Point de Gomberville PA Gomberville Magny-les-Hameaux, Île-de-France, 78114 FranceORGA-LINK is an independant CRO which proposes efficient services of Research and Development in Organic Synthesis on the scale from miligrams to kilograms. ORGA-LINK services also include extraction of natural products and analysis as well as the development of new compounds. ORGA-LINK proposes services in organic chemistry based on quality, flexibility and efficiency tailored to your needs with optimized costs. As multi-skilled chemists, we can realize every type of chemistry, from pharmaceuticals to peptide chemistry to inorganic chemistry with particularly strong expertise in the field of heterocyclic chemistry. TO KEEP YOUR TEAMS FOCUSED ON SUBJECTS OF HIGHER ADDED VALUE AND SAVE YOU BOTH TIME AND MONEY REDUCING YOUR COSTS OF SYNTHESIS : OUTSOURCE A PART OF YOUR R&D WORK. ORGA-LINK can meet your needs in term of : • Organic synthesis : multi-stage synthesis from the mg to multi-kg of derivatives, impurities, products, targets / leads and analogues • Classical or original synthesis: high pressure reaction, photosensitive (inactinic light), stable isotopic labelling (D, 13C, 15N) • R&D under contract in organic chemistry • Structural analysis, extraction • Quantitative analysis, dosage • Sourcing of compounds • Database and literature searching

6 rue Jean Calvin Paris, 75010 FranceOria Bioscience drug discovery offering purified organelles adapted to high throughput screening. Our proprietary technology enables the purification of ready-to-use organelles - lysosomes, mitochondria and soon endoplasmic reticulum—compatible with high-throughput platforms. Our organelle preparations are shippable worldy and preservable for up to one month, ensuring flexibility and scalability for pharmaceutical research Our solutions are adapted to APC, SSM-based electrophysiology, and fluorescence assays, allowing precise functional studies. We support exploration of diverse intracellular targets, including enzymes, ion channels, transporters, and GPCRs, unlocking new therapeutic pathways for complex diseases. Our products : LYSO-Preps Standard : Purified from Oria's HEK cell-line for various targets (endogenous, target KO, KD, OE, mutant). LYSO-Preps Customize : Purified from your cell lines (on demand) MITO-Preps Gen 1 : Purified mitoplast from HEK endogeneous cell lines

102 avenue Gaston Roussel Romainville, 93230 FranceOroxcell is a CRO and R&D partner in the field of ADMET (Absorption Distribution Metabolism, Excretion, Toxicity), Efficacy and Bioanalysis. For many years Oroxcell has specialized in alternative methods to animal use and extensively invested in ADMET assays using promising 3D Human Organotypic models. Oroxcell is also a state-of-the-art bioanalytical testing facility; our team will deliver you quality and reliable results thanks to our LC-MS/MS instruments and our personnel’s wide range of skills. Our clients are pharmaceutical, dermato-cosmetic, nutrition health and medical device companies. Oroxcell laboratories are regularly inspected for GLP compliance.

Osny, Île-de-France, 95520 FranceOSNY Pharma offers integrated pharmaceutical services, from formulation to commercial manufacturing and packaging, focusing on highly-potent compounds.

17, rue de Pontoise 95520 Osny - FranceOSNY Pharma offers integrated pharmaceutical services, from formulation to commercial manufacturing and packaging, focusing on highly-potent compounds.

8 Rue Maria Helena Vieira Da Silva Paris, Île-de-France, 75014 FranceOwkin is an agentic AI company on a mission to explore complex biology to speed up and scale research for the creation of new treatments and diagnostics for patients. Owkin K, our AI co-pilot combines unparalleled access to multimodal data, cutting-edge AI to quantify biology and pioneering agentic AI to achieve Biological Artificial Superintelligence in the future.

16 Boulevard Poissonnière Paris, Île-de-France, 75009 FranceOwkin is an agentic AI company on a mission to explore complex biology to speed up and scale research for the creation of new treatments and diagnostics for patients. Owkin K, our AI co-pilot combines unparalleled access to multimodal data, cutting-edge AI to quantify biology and pioneering agentic AI to achieve Biological Artificial Superintelligence in the future.

14 Boulevard Poissonnière Paris, Île-de-France, 75009 FranceOwkin is an agentic AI company on a mission to explore complex biology to speed up and scale research for the creation of new treatments and diagnostics for patients. Owkin K, our AI co-pilot combines unparalleled access to multimodal data, cutting-edge AI to quantify biology and pioneering agentic AI to achieve Biological Artificial Superintelligence in the future.

2 rue Antoine Etex Créteil, 94000 FranceOxiProteomics is a CRO pioneering an innovative approach focused on protecting and repairing skin and hair against environmental damage and biochemical stressors. Our main goal is to maintain skin and hair health through science-based solutions, delivering science-based results. Specializing in providing innovative testing solutions, ranging from human cell cultures (such as keratinocytes, fibroblasts, melanocytes, and sebocytes) to advanced human skin models, scalp tissue, hair strands, and hair follicle assessments. Our analytical platform is versatile, enabling protein biomarker analysis across various organ tissues and body fluids. We offer accurate, actionable, and specific Predictive biomarkers for skin health & longevity research. With our comprehensive capabilities and dedication to scientific excellence, we are committed to helping you evolve with innovative scientific testing solutions in the field of skincare and haircare.

190 rue CHAMPIONNETAt Parexel, speeding life-changing medicines to market begins by engaging patients With Heart™ With more than 24,000 life science professionals in 49 countries across six continents, Parexel’s people are the engine that drives clinical trial delivery, outcomes, and new medicines forward. We have made significant investment in our operations infrastructure to ensure consistent, predictable delivery all around the world as clinical research complexity continues to rise. Our trial execution framework integrates the latest innovations to efficiently manage increased research complexity, reach more patients while driving faster results for our customers and better outcomes for patients. And around the world, we’re investing today to develop a talent pool ready to deliver your next big breakthrough. The integration of clinical operations excellence and unparalleled regulatory consulting strength gives us an advantage when tackling the most complex trials in oncology, cell and gene therapies, rare diseases, and central nervous system disorders. We have a proven track record of strong performance in these areas, along with immunology, inflammation, and many more. We apply clinical operations and regulatory expertise to design clinical trials that help life-saving medicines reach patients sooner. From Phase I to Phase IV, global life sciences professionals work in partnership with biopharmaceutical sponsors to create trial experiences that are easier for patients to participate in and can serve as a viable care option for patients across a range of disease areas. Our depth of industry knowledge and strong track record gained over the past 40 years is moving the industry forward and advancing clinical research in healthcare’s most complex areas while our innovation ecosystem offers solutions throughout the product lifecycle – optimising data quality, creating better clinical trial experiences, and improving operational efficiencies – with the goal of driving better results for our customers and outcomes for patients. With the people, insight, and operational excellence to support a thriving R&D community, Parexel works With HeartTM to treat patients with dignity and learn from their experiences, so every trial makes a difference. In 2021, Parexel was acquired by EQT and Goldman Sachs Asset Management. We are headquartered in Raleigh, North Carolina, and employ 20,815 professionals in 49 countries. We are united by a core value that we believe influences every aspect of our work: We Care. We care about our people, our customers, our sites, and our partners.

21, quai du Clos des RosesP.A.R.I.S provides antibody solutions that perform to life science clients worldwide. Solutions for biopharmaceutical industry are development of mouse monoclonal antibodies, production of pre-clinical batches of antibodies, cross-reactivity studies of antibodies.

24 Rue D'Ulm Paris, 75005 FranceChimie ParisTech - PSL provides an original and complete education, from bachelor’s to doctorate degrees, while conducting cutting-edge research covering the entire spectrum of chemistry. Ranked with PSL University at 36th place in the Shanghai 2020 ranking (ARWU), and 46th in the Times Higher Education 2021 World Rankings, the school trains engineers in chemistry who have a keen sense of innovation. Chimie ParisTech - PSL nurtures numerous industrial and academic partnerships, both nationally and internationally. In 2019, a flow chemistry platform ("Paris Flow tech") hosted within PSL by Chimie ParisTech-PSL, in partnership with ESPCI Paris-PSL and MINES ParisTech-PSL, has been launched with the aim to develop disruptive technologies within the heart of the Paris region by forming and organizing particularly innovative partnerships with companies in the fine chemicals/pharmaceuticals and formulation/cosmetology sectors.

25-27 Boulevard Victor Hugo Clinique Ambroise Paré, 3ème étage Neuilly-sur-Seine, 92200, 92200 FranceParis IBD Center is a specialized organization dedicated to advancing patient care, research, and innovation in inflammatory bowel diseases (IBD). It develops and manages regulatory‑compliant digital tools that streamline patient pathways and support the collection of high‑quality clinical data. The company works in close collaboration with the Institut des MICI, an expert center in both IBD patient management and clinical research, strengthening its ability to deliver effective care models and robust scientific output. Scope of activity: Provides specialized services in the operational conduct of clinical studies. Supports scientific projects, care‑pathway redesign, and organizational transformation in chronic inflammatory diseases, including the implementation of the Institut des MICI’s integrated care‑research model. Research and data valorization: - Conducts clinical and scientific studies to advance understanding of IBD. - Leverages collected data to enhance medical knowledge and foster research and innovation.

11 Rue Watt, Paris-13E-Arrondissement, Île-de-France 75013, FRYour GMP Next-Gen Biosafety Partner. Compliant, Faster, Animal-Free. PathoQuest is a global CRO specializing in Next Generation Sequencing (NGS)-based biosafety testing through its iDTECT® platform. Offering GMP-compliant assays for viral safety and genetic characterization of cell and gene therapies, vaccines, and biologics, PathoQuest delivers faster, safer, and animal-free Quality Control (QC) testing. With laboratories in Paris (France) and Wayne, PA (USA), the company supports the biopharma industry worldwide.

Pathoquest France Paris, 75, 75013 FranceYour GMP Next-Gen Biosafety Partner. Compliant, Faster, Animal-Free. PathoQuest is a global CRO specializing in Next Generation Sequencing (NGS)-based biosafety testing through its iDTECT® platform. Offering GMP-compliant assays for viral safety and genetic characterization of cell and gene therapies, vaccines, and biologics, PathoQuest delivers faster, safer, and animal-free Quality Control (QC) testing. With laboratories in Paris (France) and Wayne, PA (USA), the company supports the biopharma industry worldwide.

19 route de Meulan, 78520 Limay, FrancePCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

BP 181 - 23 Rue Bossuet, Z.I. La Vigne aux Loups, 91160 Longjumeau, FrancePCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

2 Avenue de la source de la bièvre UFR Sciences de la Santé MONTIGNY-LE-BRETONNEUX, Île-de-France, 78180 FrancePelvipharm is a European preclinical CRO with 25 years of experience in translational pharmacology. We specialize in in vivo and ex vivo models dedicated to urology, women’s health, sexual medicine, cardiovascular and metabolic dysfunctions, and gene therapy for functional restoration of the lower urinary tract. Our scientific team has conducted more than 200 studies for global biotech innovators and top-10 pharma companies. Over the past four years, Pelvipharm has successfully delivered four IND-enabling packages supporting regulatory submissions in North America, further validating our scientific rigor, study robustness, and reproducibility. Our core expertise includes: • Urology: OAB, NDO, BOO, cystometry, bladder physiology • Women’s health: PCOS models, endometriosis, infertility, menopause-related dysfunctions (vasomotor symptoms, vaginal atrophy...), uterine fibroids • Sexual medicine: erectile dysfunction, female sexual arousal disorder, premature ejaculation • Gene therapy: bladder, pelvic and pain nerve targeting, functional recovery • Cardiovascular & metabolic disorders: hypertension, metabolic syndrome, obesity We provide comprehensive pharmacological evaluations, mechanism-of-action studies, vector biodistribution, functional endpoints, and full translational packages designed to accelerate decision-making and reduce development risks.

Paris, Île-de-France FrancePeritesco offers occular toxicity, efficacy testing, and imaging services.

18 avenue de l'Opéra 75001. Paris, FrancePeritesco offers occular toxicity, efficacy testing, and imaging services.

50 Route de la Reine Boulogne-Billancourt, Île-de-France, 92100 FrancePharmaLex is a leading provider of specialized services for the pharma, biotech and medical device industries. We guide you from early strategic planning activities and non-clinical requirements through clinical development, regulatory submission processes and post-approval / maintenance post-launch activities. Our experts use technology-enabled solutions to support you through the entire product lifecycle. We deliver exceptional results — going above and beyond the standard to deliver tailor-made solutions worldwide.

4, rue Pierre Fontaine Evry cedex, F-91058 FrancePhenocell is a research-based biotechnology company specialized in the creation, production, and commercialization of cellular models and bioassays for the dermo-cosmetic and pharmaceutical industry through the Noble Prize-winnning technology of iPSC. We specialize in dermatology and ophthalmology, with specific bioassays for skin pigmentation, acne (hyper seborrhea), skin dryness (hypo seborrhea), CBD testing and inflammation, and for diseases that involve retinal degeneration. Phenocell is here to help you improve and accelerate your research and discovery programs with highly relevant in vitro tools.

36 Rue Victor Basch Massy, Île-de-France, 91300 FrancePhinC is a Contract Research Organization (CRO) specialized in Quantitative Pharmacology Solutions to support biotechs in the development of drug candidates, new chemical and biological entities.

Le Campus 6 rue Jean Pierre Timbaud 78180 Montigny le Bretonneux Paris FrancePopsi Cube has a unique profile for an international Clinical Research Organisation providing distinctive and innovative dual expertise by combining clinical research implementation with the development of customized IT applications specific to the pharmaceutical industry, using agile method and digital iot for data capture optimization. Our expertise stems from many years of experience spent inside the largest CRO or pharmaceutical companies. We always considered IT as a valuable tool and as a way to improve and industrialize processes. It is our in-depth knowledge of pharmaceutical R&D which allows us to transform these tools to support a real advance in your clinical projects. Contact us to get started : +33 1 6 62 89 32 58

6 rue Jean-Pierre Timbaud Le Campus Bât A1 Sud Montigny-le-Bretonneux, Île-de-France, 78930 FrancePopsi Cube has a unique profile for an international Clinical Research Organisation providing distinctive and innovative dual expertise by combining clinical research implementation with the development of customized IT applications specific to the pharmaceutical industry, using agile method and digital iot for data capture optimization. Our expertise stems from many years of experience spent inside the largest CRO or pharmaceutical companies. We always considered IT as a valuable tool and as a way to improve and industrialize processes. It is our in-depth knowledge of pharmaceutical R&D which allows us to transform these tools to support a real advance in your clinical projects. Contact us to get started : +33 1 6 62 89 32 58

161 rue de CourcellesAt PRA Health Sciences, providing innovative solutions for our clients is what we do. But innovation just for the sake of innovation isn’t why we do it. Side-by-side with our clients, we strive to move drug discovery forward, to help them develop life-saving and life- improving drugs. We help change people’s lives for the better every single day. It’s who we are. Innovating to help people is at the heart of our process, but it’s even more than that. It’s also our privilege.

126 blvd Pereire, 75017 Paris, FrancePREDECT is an IMI-funded partnership between 9 academic, 3 SME (Small and Medium Enterprise) and 7 EU pharmaceutical partners, aiming to develop novel, advanced, complex in vitro and in vivo models for breast, prostate and lung cancers.

Avenue des Sciences 11Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

29 rue TaitboutPremier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

31 rue d'Aguesseau 92100 Boulogne Billancourt FranceProfilomic is an innovative company offering a wide range of services in chemical, lipidomic and metabolomic analyses using liquid chromatography coupled to mass spectrometry ultra-high resolution (LC-FTMS). Through in-house and public databases, our software and our dedicated statistical analysis tools, we can meet all requests for biomarker discovery and characterization of small organic molecules in the health, environment and food areas. Profilomic has access to recent LC-MS instruments: LTQ-Orbitrap Discovery™, Q-Exactive™, Exactive™ (Thermo Scientific) and Maxis Q-TOF (Bruker).

8, RUE VERNIER 75017 PARIS FRANCEQuinten is a pioneer in data science and the strategic application of data in business.

8 Rue Vernier Paris, Île-de-France, 75017 FranceQuinten is a pioneer in data science and the strategic application of data in business.

ZAC du Moulin, 24-26 Rue du Noyer, BP40, 95700 Roissy en FranceRandox Laboratories, through its business units, offer diagnostic services, life science reagents, biomarker testing services, antibody/drug assay development, and toxicology services.

156 Rue de Vaugirard Paris, Île-de-France, 75015 FranceRarecells is a biotechnology company pioneering innovative liquid biopsy solutions for early cancer detection and monitoring. Using its proprietary ISET® (Isolation by Size of Tumor cells) technology, Rarecells enables the highly sensitive, non-invasive detection of Circulating Tumor Cells (CTCs) that enter the bloodstream from the earliest stages of tumor development, often years before traditional methods can identify cancer. The CE-IVD certified ISET® platform can isolate a single cancer cell among 50 billion blood cells in just 10 ml of blood, offering unparalleled accuracy. Unlike many liquid biopsy tests based solely on circulating tumor DNA (ctDNA), Rarecells’ next-generation ISET® technology captures both CTC-DNA and ctDNA from a single stabilized blood sample, significantly enhancing sensitivity and providing a more comprehensive view of tumor biology. With its focus on early detection, recurrence monitoring, and personalized treatment, Rarecells is redefining how cancer is detected and managed.

60 rue Carnot F-92100Research Pharmaceutical Services offers manufacturing, formulation, regulatory affairs, quality assurance, molecular modeling, and clinical management.

104 avenue du général Leclerc Palaiseau, Essonne, 91120 FranceRime Bioinformatics is a research and development biotechnology company with a focus on bioinformatics. We develop services to speed up medical, agronomic and veterinary research. Our technologies grant in-depth view of bacterial and bacteriophage genomes, which is an essential prerequisite in the R&D process that leads a phage to market. We work hard to make high-performance bioinformatics accessible and promote a safe use of phage therapy for the patients and the environment ! Our technology enables us to considerably improve our knowledge of gene functions, we are 6 times faster and 100 times more accurate than current techniques. We want to make high-performance bioinformatics accessible to biologists. Our in silico studies enable us to detect the presence of genes for lysogenesis, virulence and antibiotic resistance in phages, using regulation-compliant techniques.

102, Avenue Gaston RousselRoowin offers API synthesis, custom compound synthesis, and cheminformatic services.

128 RUE LA BOETIE Paris, 75008 FrancePromote and connect with best health experts in the life sciences ecosystem identify and rank KOLs, clinical sites, investigators for scientific projects (clinical trials, advisory boards)

Paris, Île-de-France FranceScienomics is a software company specialized in molecular modeling and simulations of materials.

17 square Edouard VII Paris, 75009 FranceScienomics is a software company specialized in molecular modeling and simulations of materials.

62 Rue de Wattignies Paris, Île-de-France, 75012 FranceScreenCell, a French biotech company established in 2011, has pioneered a revolutionary technology for isolating and characterizing Circulating Tumor Cells (CTCs). This innovative, disposable method is the most cost-effective approach for isolating CTCs due to their larger size compared to other blood cells. ScreenCell® is fully committed to this approach by developing single-use devices designed to isolate circulating tumor cells (CTCs) from a simple blood sample. Our liquid biopsy technology offers a non-invasive and cost-effective alternative for accessing valuable insights into the disease, enabling cytological analyses, molecular biology studies, and even the culture of circulating tumor cells. With over 15 years of experience, ScreenCell® markets its products internationally and is part of a strong collaborative network within the scientific and medical communities. To date, more than 70,000 filtration units have been sold worldwide, and over 70 scientific publications have validated the effectiveness of our technology. Follow our page to stay up to date with our latest news, publications, clinical studies, and partnership opportunities. Together, let's advance personalized medicine!

BioPark Bâtiment D 12, rue Jean-Antoine de Baif 75013 Paris FranceScreenCell, a French biotech company established in 2011, has pioneered a revolutionary technology for isolating and characterizing Circulating Tumor Cells (CTCs). This innovative, disposable method is the most cost-effective approach for isolating CTCs due to their larger size compared to other blood cells. ScreenCell® is fully committed to this approach by developing single-use devices designed to isolate circulating tumor cells (CTCs) from a simple blood sample. Our liquid biopsy technology offers a non-invasive and cost-effective alternative for accessing valuable insights into the disease, enabling cytological analyses, molecular biology studies, and even the culture of circulating tumor cells. With over 15 years of experience, ScreenCell® markets its products internationally and is part of a strong collaborative network within the scientific and medical communities. To date, more than 70,000 filtration units have been sold worldwide, and over 70 scientific publications have validated the effectiveness of our technology. Follow our page to stay up to date with our latest news, publications, clinical studies, and partnership opportunities. Together, let's advance personalized medicine!

69-71 rue de Miromesnil Paris, 75008 FranceSemantiweb is specialized in Consumer Insights and helps leading brands better understand their targeted audiences, understand their performances and identify new trends. We analyze spontaneous online conversations posted on blogs, forums, social networks as well as online reviews. Our methodology leverages proprietary databases, algorithms, IA as well as human analysis. We help healthcare companies: - understand specific targeted audiences (for example: patients suffering from diabetes) - identify the different steps of the patient decision journey (for example: journey of patients going through menopause) - identify and track specific key opinion leaders (for example: derms, dentists, nurses) - analyze the perception of specific OTC products (for example, what drives positive reviews of health supplements).

ZI de Limay 8 Rue de Rouen, Porcheville, 78440 FranceSEQENS is a global partner in health, personal care and specialty ingredients. We empower innovation to bring the best solutions to our customers, with a constant concern for sustainability. Relying on the skills of 3300 employees, we leverage a worldwide manufacturing network, and state-of-the-art R&D centers. With more than 30 years-experience in the pharma industry, SEQENS is the undisputed Europe-based CDMO leader in the small molecule drug substance space. As an end-to-end player across the value chain, SEQENS offers a broad range of active ingredients, pharmaceutical intermediates, and personal care & specialty ingredients. We innovate, develop and industrialize the most demanding molecules, and implement the best available technologies. SEQENS is a global leader in pharmaceutical solutions, offering a comprehensive portfolio of potent APIs, custom non-cGMP and cGMP intermediates, RSMs and excipients. With our strong manufacturing capabilities and extensive R&D expertise, we're committed to delivering innovative solutions that meet the evolving needs of the industry. R&D services: Providing “R&D Standalone services” to support the discovery phase of any molecules. Wide range of analytical capabilities, GMP NMR and quality control testing, process safety, genotox impurities – Nitrosamines, and Drug repositioning. Chemistry and process development: Leveraging our network of R&D ecosystem to provide the best chemical route for any molecule at any stage. Six technological platforms to find the best chemical route: Multi-catalysis, Flow chemistry, Analytics, Polymers, Solid state characterization, and Biotechnologies. Scale-Up to industrialization (From a few kilos to multi-tons): 16 KILO Labs, 7 Pilot Plants, complementary chemistry and chemical engineering competencies for process industrialization, Project Management support (CMC), and Process safety. Manufacturing and Commercialization: Wide range of custom and proprietary molecules, production with the highest quality, safety and environmental standards Seqens supports its customers from the early stage development of their assets through commercial production: - Preclinical R&D work (route scouting, non GMP tox batches…) - Process and analytical development, QBD, kilo-lab and pilot production - cGMP clinical supply - Non-GMP / GMP intermediates, RSMs and APIs manufacturing - Standalone analytics (Nitrosamines quantification, solid state studies…) - Pre-formulation work

11 Av. des Tropiques Les Ulis, 91940 FranceSEQENS is a global partner in health, personal care and specialty ingredients. We empower innovation to bring the best solutions to our customers, with a constant concern for sustainability. Relying on the skills of 3300 employees, we leverage a worldwide manufacturing network, and state-of-the-art R&D centers. With more than 30 years-experience in the pharma industry, SEQENS is the undisputed Europe-based CDMO leader in the small molecule drug substance space. As an end-to-end player across the value chain, SEQENS offers a broad range of active ingredients, pharmaceutical intermediates, and personal care & specialty ingredients. We innovate, develop and industrialize the most demanding molecules, and implement the best available technologies. SEQENS is a global leader in pharmaceutical solutions, offering a comprehensive portfolio of potent APIs, custom non-cGMP and cGMP intermediates, RSMs and excipients. With our strong manufacturing capabilities and extensive R&D expertise, we're committed to delivering innovative solutions that meet the evolving needs of the industry. R&D services: Providing “R&D Standalone services” to support the discovery phase of any molecules. Wide range of analytical capabilities, GMP NMR and quality control testing, process safety, genotox impurities – Nitrosamines, and Drug repositioning. Chemistry and process development: Leveraging our network of R&D ecosystem to provide the best chemical route for any molecule at any stage. Six technological platforms to find the best chemical route: Multi-catalysis, Flow chemistry, Analytics, Polymers, Solid state characterization, and Biotechnologies. Scale-Up to industrialization (From a few kilos to multi-tons): 16 KILO Labs, 7 Pilot Plants, complementary chemistry and chemical engineering competencies for process industrialization, Project Management support (CMC), and Process safety. Manufacturing and Commercialization: Wide range of custom and proprietary molecules, production with the highest quality, safety and environmental standards Seqens supports its customers from the early stage development of their assets through commercial production: - Preclinical R&D work (route scouting, non GMP tox batches…) - Process and analytical development, QBD, kilo-lab and pilot production - cGMP clinical supply - Non-GMP / GMP intermediates, RSMs and APIs manufacturing - Standalone analytics (Nitrosamines quantification, solid state studies…) - Pre-formulation work

4 Rue du Commandant d’Estienne d’Orves Villeneuve-la-Garenne, 92390 FranceSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

29 Avenue Aristide Briand Arcueil , 94110 FranceSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

Bd Salvador AllendeShimadzu offers analytical technology, laboratory instruments, testing machines, and scales.

19 Rue de Verdun Suresnes, Île-de-France, 92150 FranceSocosur specializes in chemicals distribution.

41-43 rue PergolèseSogeti offers information technology support as well as software and systems development.

100 rue 75019 FranceSince the year 2000, our teams of industry experts have created the world's largest online professional network dedicated to chemicals and materials. This network includes more than 500,000 engineers, formulators, product developers, marketers, applicators and brand owners across the globe. Through our vertical industry websites, these professionals have unlimited access to Universal Selectors aimed at gathering all chemicals & materials in the world, and the knowledge to select them through high value content such as Product Selection Guides and Online Courses.

100, rue Petit 75019 Paris FranceSince the year 2000, our teams of industry experts have created the world's largest online professional network dedicated to chemicals and materials. This network includes more than 500,000 engineers, formulators, product developers, marketers, applicators and brand owners across the globe. Through our vertical industry websites, these professionals have unlimited access to Universal Selectors aimed at gathering all chemicals & materials in the world, and the knowledge to select them through high value content such as Product Selection Guides and Online Courses.

3 allée Thérésa CS 10009 92665 Asnières sur Seine Cedex FranceThe Stago Group has therefore developed and acquired its expertise over many years, accompanying, and often leading, the rapid growth of this Haematology-related scientific discipline. Which is why Stago is today the only independent international group in the In Vitro Diagnostics industry dedicated to Haemostasis and Thrombosis exploration.

1 Avenue de l’Atlantique Les Conquérants, Bat. Kilimandjaro Les Ulis, 91940 FranceStandard BioTools Inc. (Nasdaq: LAB), has an established portfolio of essential, standardized next-generation technologies that help biomedical researchers develop medicines faster and better. As a leading solutions provider, the company provides reliable and repeatable insights in health and disease using its proprietary SomaScan, mass cytometry and microfluidics technologies, which help transform scientific discoveries into better patient outcomes. Standard BioTools works with leading academic, government, pharmaceutical, biotechnology, plant and animal research and clinical laboratories worldwide, focusing on the most pressing needs in translational and clinical research, including oncology, immunology and immunotherapy.

Résidence Boissy, 4STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

Franconville, Île-de-France, 95130 FranceSTERIGENE offers process and cleanroom equipment.

2 rue André Citroen Franconville, 95130 FranceSTERIGENE offers process and cleanroom equipment.

Guy Môquet 94800 66 rue Villejuif France

1 MAIL DU PARV DU PR GEORGES MATHE VILLEJUIF, ILE DE FRANCE, 94800 FranceSvar Life Science is a Swedish group of companies that invents, develops, and applies the best assay technology for drug development and clinical diagnostics with the goal of delivering new solutions tailored to customer requirements. Our multiple locations worldwide and experience in assay development, bioanalysis, and clinical diagnostics make us an ideal partner for pharma, biotech, and CROs. Svar Life Science offers a comprehensive portfolio of products and solutions: ● Functional and biomarker assays that can be used to explore every angle of complement system-involved in a wide range of application areas. ●The iLite® cell-based solutions that are based on the iLite technology, a cleverly engineered cell-based assay system with a dual reporter gene readout. ●Cell-based custom development services including an assay-ready cell service and master cell bank development. ●CRO Services include Bioanalytical Services, Biomarker Discovery Services, and GMP QC Testing Services. Our GMP, GCP, GLP, and ISO 15189-compliant laboratory is designed to offer assay development, validation, and sample analysis for pre-clinical as well as clinical studies. We have experience with various immunoassays including ELISA, MSD, SIMOA, Olink Proteomics technology, and cell-based assays. We work to deliver the right answers at the right time to improve patient care and accelerate drug development. Our subsidiary: ●Wieslab is our diagnostic laboratory services offering a comprehensive range of clinical diagnostic tests within neuro-immunology, nephrology, rheumatology, and gastroenterology for clinicians and laboratories worldwide.

L'Orme des Merisiers Départementale 128 Saint Aubin, 91190 FranceShareholding of the French public centers CNRS and CEA, SOLEIL serves the international scientific community and industry. It is also a place for dissemination of scientific culture. Accelerator for innovation, growth and business competitiveness, SOLEIL makes available advanced skills and high performance equipment to manufacturers and industry service providers, and involves scientific instrumentation companies in its technological research: upstream within the framework of collaborative projects and downstream in the industrial and commercial exploitation of innovative devices designed by its teams.

4 Rue Pierre Fontaine Genopole Entreprises Évry, Île-de-France, 91058 FranceCreated in 2013, SYNSIGHT is a game changer in drug discovery by developing the first platform combining cell-based microscopy that train AI models, to generate new chemical entities. The benefits are to increase the productivity of your R&D and secure your drug discovery programs. Its innovative platform and technologies can be directly applied to RNA-protein and protein-protein interactions. Its cellular assay is unique and is able to qualify and quantify directly in human cells these challenging interactions. The MTBench characterizes the efficacy of small molecule modulators in cell (Hit identification and IC50 measurement). This cellular assay, easy to setup as medium or high-throughput screening level combined to biophysical assays, are then able to train our multiparametric AI models to select and generate new chemical entities.

23 Boulevard François Mitterrand Laboraoire SABNP - Bat. Maupertuis - Université d'Évry Évry, Île-de-France, 91000 FranceCreated in 2013, SYNSIGHT is a game changer in drug discovery by developing the first platform combining cell-based microscopy that train AI models, to generate new chemical entities. The benefits are to increase the productivity of your R&D and secure your drug discovery programs. Its innovative platform and technologies can be directly applied to RNA-protein and protein-protein interactions. Its cellular assay is unique and is able to qualify and quantify directly in human cells these challenging interactions. The MTBench characterizes the efficacy of small molecule modulators in cell (Hit identification and IC50 measurement). This cellular assay, easy to setup as medium or high-throughput screening level combined to biophysical assays, are then able to train our multiparametric AI models to select and generate new chemical entities.

34 rue de la Croix de Fer CS 30158 Saint-Germain-en-Laye, 78100 FranceTakara Bio Europe provides kits, reagents, instruments, and services that enable life sciences researchers to achieve their experimental objectives. As a member of the Takara Bio Group, Takara Bio Europe is part of a company that holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Going forward, Takara Bio Europe will continue to develop high-quality, innovative tools and services that accelerate scientific discovery. For researchers in the USA, please visit "Takara Bio USA's profile here":https://app.scientist.com/domain_switcher?redirect=/providers/ba5e2593-0a26-4dda-93b6-b07ddb7823b1

39 Rue de Houdan Le Perray-en-Yvelines, Île-de-France, 78610 Francetebubio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

39 rue de Houdan BP 15 Le Perray-en-Yvelines, 78612 Francetebubio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

39 Rue de Houdan Le Perray en Yvelines, Yvelines, 78610 Francetebubio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

28Rue Claude BernardTelstar Life Science Solutions designs, manufactures, sell and support of high technology equipment solutions for the pharmaceutical, biotech and related industries

1 Rue Pierre Fontaine Evry, 91000 FranceTexcell-North America, Inc. is a global contract research organization based in the Maryland/Virginia biotech corridor specializing in custom cell culture, virus propagation, virus concentration, viral clearance services, and viral safety testing in support of biopharmaceutical applications submitted to the FDA and other regulatory authorities. Since 2002, our team has cultivated an ever-increasing range of experience performing viral clearance studies for a wide variety of purification steps including chromatography, filtration, and inactivation methods, as well as evaluations of column age and sanitization, or cleaning efficacy. We offer our clients a personalized and tailored approach to study design with the advantage of an extensive historical viral clearance database of over 9,000 studies performed by our global organization. Through partnerships with other Texcell facilities around the world, we have expanded our services portfolio to include cGMP cell bank production, cell bank characterization and GMP compliant animal studies. We are proud to support research that continues to improve global quality of life.

26 rue d’Ulm Paris , 75248 FranceThe Institute Curie/CNRS Chemical Library was created from the chemical molecules synthesized by the chemists of the Institute Curie of Paris and Orsay. This academic chemical library, one of the most important of France, contains almost 10000 substances. Such a set of chemicals is constituted not only of the final products, but also of synthetic intermediates obtained during the programs of optimization against various therapeutic targets. Since its creation, 65 years ago, the main motivation of the chemistry laboratory of the Institute Curie has been the discovery of molecules for cancer treatment. A direct consequence of this activity is the existence (often in significant quantities) of samples of several thousands of synthesized compounds. Moreover, advances in proteomics and genomics have led to the discovery of an increasing number of new protein targets with therapeutic potential. The Chemical Library consists of 15,509 unique structures including 9891 compounds available in powder and 9200 compounds available in solution.

8è étage, 26 rue d’Ulm Paris, 75005 FranceThe genomics platform provides to basic, translational, and medical research teams with high throughput technological tools for analyzing gene structure and expression in various organisms, cellular models, and tumors. Structural alterations in genomes, such as mutations, gains, amplifications, loss of genomic regions, polymorphisms, allelic imbalances, loss of heterozygosity are identified using SNP arrays, Nanostring analysis, Sanger sequencing, or qPCR. Gene expression is complex and may be addressed at multiple levels. Coding and non-coding transcript for proteins can be quantified using Affymetrix chip for a pangenomic analysis, or using NanoString tools, or via qPCR depending on the number of samples and markers to quantify. The platform analyses the regulation of gene expression by quantifying microRNA, non-coding functional RNA, and other specific types of RNA, which modulate gene expression at various levels (transcription and translation). Such quantifications are performed by using Affymetrix chips or via NanoString multiplexing tools. Technics for quantifying certain epigenetic markers are currently being tested to meet internal demand (OxBS method developed by Cambridge Epigenetix).Other technics to analyse the chromatin conformation are being setup (in situ HiC, Uveal Melanoma project, with Pr. E. Heard) to enrich our portfolio of activities

26 rue d’Ulm Paris , 75248 FranceThe NGS Platform of the Institut Curie has greatly evolved since 2012 mainly with the financial support of ICGEx grant obtained in the frame of the EQUIPEX « investissement d’avenir » competitive call. This grant allowed to purchase high throughput NGS sequencers, to fully equip a dedicated lab at the 7th floor of the hospital and expand the staff in charge of running sequencing projects. Under the supervision of Olivier Delattre and Alain Nicolas, the NGS platform provides state of the art services in sequencing. This includes the organization of pre-run meetings where the choice of the most appropriate technical strategy is defined in order to best address the biological question of collaborators. Multiple sequencing protocols have been developed and routinely used in the platform to cover most commonly used applications in genetics and epigenetics (Genome, Exome and targeted resequencing, RNA sequencing, DNA methylation sequencing, ChIP-seq …). Furthermore, we are also willing to co-develop more specific protocols according to the need of research teams of the Institute.

37th-39th, Ledru-Rollin Avenue Office 710 Paris 75012 FranceTheorem Clinical Research offers full service clinical research solutions including DM, biostatistics, programming including CDISC, PM, clinical operations, and regulatory affairs.

14 Rue Ambroise Croizat Croissy-Beaubourg, 77183 FranceWith more than 25 years experience of developing, manufacturing, and marketing innovative in-vitro diagnostics, Theradiag is now strengthening its presence in theranostics. Our new name, Theradiag, illustrates this approach. With CE marking in 2010 and the launch in 2011 of the first Lisa-Tracker kits, we are expanding this panel by developing and launching new kits. Our goal is to offer clinicians and patients a wide range of biotherapy monitoring kits. We have built the foundations for this new activity based on our knowledge of autoimmune diseases. In the coming months, we will be extending our offer to assist in the monitoring of biotherapies in other treatment areas, such as infectious diseases and cancer. We will also continue to develop our traditional activity in IVD, and specifically autoimmunity and innovative oncogenetic diagnostics. This technological and innovative evolution will allow Theradiag to better serve its clients and contribute to improving the bio-therapeutic treatments of today and the future.

109, rue des Cotes Maisons-Laffitte 78600 FranceFounded in 1989, Thorlabs has its headquarters in Newton, NJ. This location is also home to our mechanics, optics, fiber, advanced systems technology, and advanced applications teams as well as one of our three distribution warehouses. On-site manufacturing allows us to customize our products quickly and efficiently to meet specialized customer requests. Our technical support team, call center, marketing, and web development teams make their homes in Newton as well, and are dedicated to providing comprehensive customer support and services.

54 Rue de Londres Paris, Île-de-France, 75008 FranceTox by Design is a leading European toxicological expertise company specializing in impurity risk assessments. Our services cover a wide range of pharmaceutical sectors, including APIs, cosmetics and medical devices. Our expert team thoroughly reviews all ICH and EMA requirements to ensure your products and manufacturing processes align with the latest industry standards. We have extensive access to tox literature and validated in-silico solutions in order to provide our clients with the most relevant information to support the research, development, and validation of their products. We take pride in recruiting top-of-the-class, European registered toxicologists who deliver outstanding service. Learn more at our website www.toxby.design and get a quotation today to see how your company can benefit from our toxicology and regulatory compliance expertise.

54 rue de Londres 75008 PARIS, IDF, 75008 FranceTox by Design is a leading European toxicological expertise company specializing in impurity risk assessments. Our services cover a wide range of pharmaceutical sectors, including APIs, cosmetics and medical devices. Our expert team thoroughly reviews all ICH and EMA requirements to ensure your products and manufacturing processes align with the latest industry standards. We have extensive access to tox literature and validated in-silico solutions in order to provide our clients with the most relevant information to support the research, development, and validation of their products. We take pride in recruiting top-of-the-class, European registered toxicologists who deliver outstanding service. Learn more at our website www.toxby.design and get a quotation today to see how your company can benefit from our toxicology and regulatory compliance expertise.

2-4, rue Jean Baptiste HuetTransgenic Rabbit Models offers transgenic rabbit models for the study of atherosclerosis, ophtalmology, hypertrophic myopathies, diabetes, obesity, hemostasis, respiratory diseases, AIDS, and cancer.

Tour Franklin 92042 Paris La Défense Cedex FranceUnipex distributes specialty products including API, excipients, and other formulations.

55 avenue de ParisUniversity of Versailles Saint Quentin en Yvelines (UVSQ) focuses on research with laboratories for cellular biology, microbiology, pathology, oncology, and pharmacology.

42 Boulevard Jourdan Paris, Île-de-France, 75014 FrancePreclinical Services in Large and Small Animal Models

42 BOULEVARD JOURDAN PARIS, 75014 FrancePreclinical Services in Large and Small Animal Models

11 grand chemin de Bligny Fontenay-lès-Briis, 91640 FrancePreclinical Services in Large and Small Animal Models

Évry, Île-de-France FranceWatchFrog offers in vivo drug efficacy evaluation, high throughput screening, eco-toxicological screening, and target validation services.

Pépinière Genopole Entreprises 4 rue Pierre Fontaine 91000 Evry FranceWatchFrog offers in vivo drug efficacy evaluation, high throughput screening, eco-toxicological screening, and target validation services.

4 rue Pierre Fontaine Evry-Courcouronnes, 91000 FranceXenTech is an oncology preclinical CRO specializing in Patient-Derived tumor Xenografts (PDX). We test anticancer drug activity in our PDXs and identify drug response biomarkers. Cell lines derived from our PDX are available for in vitro assays and we also offer Immuno-Oncology PDX (syngeneic and PBMC humanized models) to test I/O checkpoints and combinations with existing or emerging therapies. Our expertise : World-renowned Breast PDX collection, extensively pubished and characterized for all DDR aspects (HRD scores, RAD51 scores, PARP inhibitor responses,...). Special PDX range (Match-R) focusing on Acquired Resistance to the LATEST targeted Therapies (osimetinib, dabrafenib, trametinib, erdafitinib,...) A large collection of Prostate PD models (cRPCs, ...)

1-3 Impasse Alexis Trinquet Évry-Courcouronnes, Île-de-France, 91000 FranceXenTech is an oncology preclinical CRO specializing in Patient-Derived tumor Xenografts (PDX). We test anticancer drug activity in our PDXs and identify drug response biomarkers. Cell lines derived from our PDX are available for in vitro assays and we also offer Immuno-Oncology PDX (syngeneic and PBMC humanized models) to test I/O checkpoints and combinations with existing or emerging therapies. Our expertise : World-renowned Breast PDX collection, extensively pubished and characterized for all DDR aspects (HRD scores, RAD51 scores, PARP inhibitor responses,...). Special PDX range (Match-R) focusing on Acquired Resistance to the LATEST targeted Therapies (osimetinib, dabrafenib, trametinib, erdafitinib,...) A large collection of Prostate PD models (cRPCs, ...)

4, rue Pierre Fontaine Evry, F 91000 FranceXenTech is an oncology preclinical CRO specializing in Patient-Derived tumor Xenografts (PDX). We test anticancer drug activity in our PDXs and identify drug response biomarkers. Cell lines derived from our PDX are available for in vitro assays and we also offer Immuno-Oncology PDX (syngeneic and PBMC humanized models) to test I/O checkpoints and combinations with existing or emerging therapies. Our expertise : World-renowned Breast PDX collection, extensively pubished and characterized for all DDR aspects (HRD scores, RAD51 scores, PARP inhibitor responses,...). Special PDX range (Match-R) focusing on Acquired Resistance to the LATEST targeted Therapies (osimetinib, dabrafenib, trametinib, erdafitinib,...) A large collection of Prostate PD models (cRPCs, ...)

101, rue de Sèvres Lot 1674 Paris, 75279 CEDEX 06 FranceYOLARX Consultants is a privately-owned company that has successfully provided services in pharmacoepidemiology for almost 20 years. Since its inception in 2006, YOLARX has evolved into a boutique research organization with a North American headquarter in Montreal (Canada) and a European headquarter in Paris (France). A staff of 15 provides services in pharmacoepidemiology, data science, therapeutic risk management and pharmacovigilance, to a global client base of large, medium, and small pharmaceutical companies. YOLARX has conducted projects in all therapeutic areas, including rare diseases, across all regions – critical and literature reviews (systematic, rapid/targeted, scoping, umbrella), data landscaping, feasibility assessment, data analysis, post-authorization safety studies. Our proprietary Yolarx SLRTM platform increases the efficiency of the literature reviews we conduct by leveraging AI technology, including natural language processing, for the selection of sources and data extraction. Our proprietary RWD Tracker© platform is a unique AI-powered online library of real-world data (RWD) sources. For each data landscaping project, YOLARX leads the industry in creating a knowledge base of data sources that is customized to our client’s business needs. Our reputation is derived from well-established values: Quality, Innovation, Commitment, Respect, Collaboration, Responsibility & Reliability. The academic appointments and affiliations held by the members of our organization enhance the credibility of our work and are testimony of the high standards to which we adhere. For additional information about our company and our services, please visit our website at: www.yolarx.com.

101 Rue de Sèvres Lot 1674 Paris, Île-de-France, 75007 FranceYOLARX Consultants is a privately-owned company that has successfully provided services in pharmacoepidemiology for almost 20 years. Since its inception in 2006, YOLARX has evolved into a boutique research organization with a North American headquarter in Montreal (Canada) and a European headquarter in Paris (France). A staff of 15 provides services in pharmacoepidemiology, data science, therapeutic risk management and pharmacovigilance, to a global client base of large, medium, and small pharmaceutical companies. YOLARX has conducted projects in all therapeutic areas, including rare diseases, across all regions – critical and literature reviews (systematic, rapid/targeted, scoping, umbrella), data landscaping, feasibility assessment, data analysis, post-authorization safety studies. Our proprietary Yolarx SLRTM platform increases the efficiency of the literature reviews we conduct by leveraging AI technology, including natural language processing, for the selection of sources and data extraction. Our proprietary RWD Tracker© platform is a unique AI-powered online library of real-world data (RWD) sources. For each data landscaping project, YOLARX leads the industry in creating a knowledge base of data sources that is customized to our client’s business needs. Our reputation is derived from well-established values: Quality, Innovation, Commitment, Respect, Collaboration, Responsibility & Reliability. The academic appointments and affiliations held by the members of our organization enhance the credibility of our work and are testimony of the high standards to which we adhere. For additional information about our company and our services, please visit our website at: www.yolarx.com.

101, rue de Sèvres Lot 1674 Paris, 75279 CEDEX 6 FranceYOLARX Consultants is a privately-owned company that has successfully provided services in pharmacoepidemiology for almost 20 years. Since its inception in 2006, YOLARX has evolved into a boutique research organization with a North American headquarter in Montreal (Canada) and a European headquarter in Paris (France). A staff of 15 provides services in pharmacoepidemiology, data science, therapeutic risk management and pharmacovigilance, to a global client base of large, medium, and small pharmaceutical companies. YOLARX has conducted projects in all therapeutic areas, including rare diseases, across all regions – critical and literature reviews (systematic, rapid/targeted, scoping, umbrella), data landscaping, feasibility assessment, data analysis, post-authorization safety studies. Our proprietary Yolarx SLRTM platform increases the efficiency of the literature reviews we conduct by leveraging AI technology, including natural language processing, for the selection of sources and data extraction. Our proprietary RWD Tracker© platform is a unique AI-powered online library of real-world data (RWD) sources. For each data landscaping project, YOLARX leads the industry in creating a knowledge base of data sources that is customized to our client’s business needs. Our reputation is derived from well-established values: Quality, Innovation, Commitment, Respect, Collaboration, Responsibility & Reliability. The academic appointments and affiliations held by the members of our organization enhance the credibility of our work and are testimony of the high standards to which we adhere. For additional information about our company and our services, please visit our website at: www.yolarx.com.