Essex, ON CanadaAmicus Biotech specializes in avian and mammalian antibody production.

9056 Ferris Sd. Rd. RR#1 Essex, Ontario N8M 2X5 CanadaAmicus Biotech specializes in avian and mammalian antibody production.

2355 Derry Road East,Unit #23,Mississauga, Ontario, Canada,L5S 1V6Anogen, trade name of Yes Biotech Laboratories, offers antibody detection, production, and conjugation services.

Toronto, ON CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

80 St. George Street Suite 615 Toronto, Ontario M5S 3H6 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

2395 Speakman Drive, Suite 2111 Mississauga, ON, L5K 1B3 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

755 Queensway E, Unit 24 Mississauga, ON, L4Y 4C5 CanadaAcanthus Research provides you with high-quality analytical standards and organic chemistry services. Primary Client Industries: Pharmaceutical, Biotechnology, Research Labs, and related industries. Our Products: • Stable isotope-labelled analogues • Metabolites including conjugates such as glucuronides • Degradation products and process impurities • Active pharmaceutical ingredients • Genotoxic impurities • Related substances for pharmacopeial updates

1600 Industrial Road Cambridge, ON, N3H 4W5 CanadaAdvanced Electrophoresis Solutions Ltd (AES) is a market leader for protein charge variant separation and characterization. AES has been working with leading biopharmaceutical research & producers answering their diversely urgent needs. AES has been providing critical reagents including a wide range of carrier ampholytes and pI markers supplied for essential lot release quality control (QC) of commercial therapeutic proteins, which saves millions of dollars for our customers for potential product disruption, exploration of replaced QC method, or file applications for revalidating SOPs to the regulatory agency. AES’s essential product: CEinfinite system is the only platform for high throughput reliable analytical iCIEF and both online iCIEF-MS coupling and off-line preparative iCIEF to do cross-verification and jointly conduct comprehensive and in-depth research on charge isomers.

380 Jamieson pkwy Unit 7&8 Cambridge, ON, N3C 4N4 CanadaAdvanced Electrophoresis Solutions Ltd (AES) is a market leader for protein charge variant separation and characterization. AES has been working with leading biopharmaceutical research & producers answering their diversely urgent needs. AES has been providing critical reagents including a wide range of carrier ampholytes and pI markers supplied for essential lot release quality control (QC) of commercial therapeutic proteins, which saves millions of dollars for our customers for potential product disruption, exploration of replaced QC method, or file applications for revalidating SOPs to the regulatory agency. AES’s essential product: CEinfinite system is the only platform for high throughput reliable analytical iCIEF and both online iCIEF-MS coupling and off-line preparative iCIEF to do cross-verification and jointly conduct comprehensive and in-depth research on charge isomers.

101 College Street, Suite 335 Toronto Ontario M5G 1L7 CanadaAIM Therapeutics offers development of treatments for asthma, bronchitis, spinal injuries, diabetes, restenosis, and other inflammatory conditions.

41 Bittern Street Ancaster, Ontario, L9G 4V5 CanadaActivation Laboratories offers protein testing, materials testing, chromatography, spectroscopy, biomarker discovery, and wet chemistry services.

610 University Avenue Room 9-715 Toronto, Ontario, M5G 2M9 CanadaAdela will provide an advanced blood test to detect multiple high-morbidity, high-mortality diseases before symptoms occur, and to enable management through the entire care continuum. Adela's ability to detect many diseases through a single platform with best-in-class performance sets it apart from other liquid biopsy companies.

Toronto, ON CanadaAccre Chemicals is a contract research organization of new drug discovery, pharmaceuticals, medicinal chemistry research, chemical libraries and custom chemical synthesis.

2640 Midland Avenue Toronto, Ontario M1S1R7 CanadaAccre Chemicals is a contract research organization of new drug discovery, pharmaceuticals, medicinal chemistry research, chemical libraries and custom chemical synthesis.

41 Bittern Street Ancaster, ON, Canada L9G 4V5The Actlabs Group of Companies provides contract analytical services covering all aspects of analysis from academic research applications to routine quality control functions. We provide our services to many fields, including Agriculture, Geochemical, Petroleum, Industrial Minerals, Forensic, Pharmaceutical & Clinical, Environmental & Occupational Health and Materials Testing areas.

1348 Sandhill Drive Hamilton, ON, L9G 4V5 CanadaAffinity Biologicals Inc. (Affinity) was founded in 1987 by the principals Hugh and Patricia Hoogendoorn. With a strong background in hemostasis research and a focus on reagent development, Affinity has become a primary manufacturer of more than 250 reagents and kits used in hemostasis and thrombosis research and diagnostics. Our product line includes: coagulation related antibodies, matched-pair antibody sets for ELISA, depleted/deficient plasmas, protease inhibitor deficient plasmas, the VisuLize™ line of complete ELISA kits and the VisuCon™ & VisuCal™ coagulation controls and calibration plasmas. All Affinity Biologicals products are manufactured in our Ancaster, ON (Canada) facility, products are sold direct in North America and world wide through a network of branded and private-label distributors.

10 Nugent Road Surrey Research Park Guidford, Surrey, GU2 7AF United KingdomANGLE is a world-leading liquid biopsy company with innovative circulating tumour cell (CTC) diagnostic solutions for use in research, drug development and clinical oncology using a simple blood sample. ANGLE's FDA cleared and patent protected circulating tumour cell (CTC) harvesting technology known as the Parsortix® PC1 System enables complete downstream analysis of the sample including whole cell imaging and proteomic analysis and full genomic and transcriptomic molecular analysis.

60 Leonard Avenue Toronto, ON, M5T0S8 CanadaAtuka provides contract research and consultancy services for the biopharmaceutical industry with world-leading expertise in Parkinson's disease and other neurological conditions. We combine cutting-edge pre-clinical rodent and primate efficacy testing including a comprehensive range of motor and non-motor assays (e.g. cognition and impulse control) with medicinal chemistry services, DMPK and in-vivo imaging in aiding the development of novel therapeutics and diagnostics.

Saint Catharines, ON CanadaBiolyse Pharma offers custom GMP aseptic sterile filling and produces Paclitaxel while conducting research and development of natural compounds for therapeutic applications.

59 Wellandvale rd. St. Catharines, Ontario L2S 3Y2 CanadaBiolyse Pharma offers custom GMP aseptic sterile filling and produces Paclitaxel while conducting research and development of natural compounds for therapeutic applications.

299 John Bowser Crescent Newmarket, Ontario L3Y 7N9 CanadaBiostatistiX offers solutions and platforms in support of profiling mechanism of actions of new chemical entities, biomarkers, and gene expression.

6790 Kitimat Road, Unit 4 Mississauga, Ontario L5N 5L9 CanadaBecquerel Laboratories offers elemental analysis using radioactivity to analyze radioactive and non-radioactive materials.

Hamilton, ON CanadaBay Area Genetic Laboratory (BAGL) is a fully licensed and accredited Canadian testing facility which provides research and clinical genetic testing throughout North America.

565 Sanatorium Road, Suite 205B, Sir William Osler Building Hamilton, ON L9C 7N4 CanadaBay Area Genetic Laboratory (BAGL) is a fully licensed and accredited Canadian testing facility which provides research and clinical genetic testing throughout North America.

100 College St Suite 322 Toronto, ON, M5G1L5 United StatesBioAspect SERVICES conducts efficacy and proof-of-principle studies in cellular, transgenic Drosophila, and rodent models of to identify health benefits of pharmaceutical, biotechnology, and nutraceutical products. BioAspect PRODUCTS supplies products for life science research including kits and assays, antibodies, proteins, human primary cells, benchtop lab equipment and many more.

100 College St., Suite 320, Toronto ON M5G1L5 CanadaBioAspect SERVICES conducts efficacy and proof-of-principle studies in cellular, transgenic Drosophila, and rodent models of to identify health benefits of pharmaceutical, biotechnology, and nutraceutical products. BioAspect PRODUCTS supplies products for life science research including kits and assays, antibodies, proteins, human primary cells, benchtop lab equipment and many more.

Waterloo, ON CanadaThe mission of BSI is to make a positive difference in proteomic research, primarily through professionally supported software and by providing committed international leadership through standards of excellence.

500-1919 Minnesota Court Mississauga, Ontario, L5N 0C9 CanadaMaxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

6740 Campobello Rd., Mississauga, ON L5N 2L8Maxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

4141 Sladeview Crescent, Unit 10, Mississauga, ON L5L 5T1 CanadaMaxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

32 Colonnade Road North, Unit 1000 Nepean, ON K2E 7J6 CanadaMaxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

4053 Meadowbrook Drive, Unit 101, London, ON N6L 1E8 CanadaMaxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

1060 Lorne St, Unit 7 Sudbury, ON P3C 1A5 CanadaMaxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

90 Frobisher Drive, Unit #2 Waterloo, ON N2V 2A1 CanadaMaxxam Analytics provides analytical services, assay development, spectrometry, and product-related services.

4 Third Ave Kitchener, Ontario, N2C1N6 CanadaWelcome to Biomatik - Quality Products & Services for Life Sciences and Drug Discovery! Offered Products: 31,000+ ELISA Kits, 14,000+ Antibodies, 17,000+ Proteins, 230+ Biochemicals. Offered Services: Gene Synthesis, Peptide Synthesis, Protein Expression & Purification, Antibody Production, and Antibody Sequencing Services.

5180 Orbitor Drive Unit 101 Mississauga, Ontario, L5W 5L9 CanadaBioCache Lab Solutions Inc. (BioCache) provides secure management of archived cells / tissues, fluids, genetic and other organic materials. BioCache also offers high resolution scanning and data management services related to these priceless biospecimens. BioCache also provides CRO services such as animal model development, imaging and pre-clinical studies or run preclinical studies in mouse / large animal models quickly and efficiently. BioCache can leverage the hospitals’ world leading expertise to give clients access to clinical samples for a range of biomarker analyses, in-vivo/ ex-vivo models of disease, sequencing, single cell-omics or genetic engineered mouse models of disease. All of this is further supported by secure cloud data storage capacity and remote accessibility. https://www.biocache.com/research-services Available services include: Pathology, immunohistochemistry, multiplex fluorescence with image analysis Patient derived preclincal models CLIA Laboratory diagnostic development Live animal imaging studies Analytical chemistry and metabolic profiling Sequencing and single cell-omics Slide scanning, and data storage/remote viewing Genetic engineered mouse models of disease

23 Woodlawn Road Toronto, ON L3P 7G7 CanadaAn Integrated Contract Chemistry Service Organisation Since 2010, Bellen Chemistry has been providing chemistry CRO/CDMO services as an integrated Contract Chemistry Service Organization. With years of accumulated technical advantages and experience in chemical synthesis of small molecule compounds, Bellen has built a one-stop-shop chemistry service platform, supporting big pharmas, biotech innovators and new drug development institutions for their research programs from discovery to commercial stage through comprehensive chemistry solutions. Our R&D, production, sales and operation team are based globally and at present, Bellen has nearly 1,000 employees worldwide, of which our technical team accounts for around 50%. Bellen is committed to continuing investing in innovation and state-of-the-art facilities to enable a one-stop-shop chemistry service platform, adding value to your project from library synthesis to API GMP manufactory. Our Key Services & Capabilities: - Key intermediates & RSMs (non-GMP & GMP) - cGMP APIs - Flow chemistry & Biocatalysis - Process development & optimisation - Process safety assessment - Early phase scale up - Late phase API & intermediates manufacturing - Solid Phase & Recrystallisation platforms (New for 2023) Watch our introductory video here: https://www.youtube.com/watch?v=6EoahD-c6WI

140 Columbia St W Suite 202 Waterloo, Ontario, N2L3K8 CanadaThe mission of Bioinformatics Solutions, Inc. (BSI) is to further life science research through the collaboration with pharmaceutical and biotechnology companies to offer advanced and innovative proteomic solutions. We focus our resources on providing solutions to computational biomedicine with machine learning and advanced algorithms to gain comprehensive knowledge from proteomics, genomics, and medicine. We believe our strongest asset is our ability to bring together the right people: pioneering scientists, award-winning researchers, technology innovators and intelligent developers to execute our mission.

1425 Strasburg Road Unit 1B Kitchener, ON, N2R 1H2 CanadaThe mission of Bioinformatics Solutions, Inc. (BSI) is to further life science research through the collaboration with pharmaceutical and biotechnology companies to offer advanced and innovative proteomic solutions. We focus our resources on providing solutions to computational biomedicine with machine learning and advanced algorithms to gain comprehensive knowledge from proteomics, genomics, and medicine. We believe our strongest asset is our ability to bring together the right people: pioneering scientists, award-winning researchers, technology innovators and intelligent developers to execute our mission.

20 Konrad Crescent Markham, ON, L3R 8T4 CanadaSince 2004, BioBasic Inc has been a trusted partner in the life sciences industry for supporting scientific research and innovation. As a direct manufacturer, we offer a wide selection of high-quality materials, reagents and services such as DNA Sequencing, Gene Synthesis, Protein expression & Purification, Peptide Synthesis and Antibody Production. We also have the industrial capacity to provide corresponding services in bulk as well as under GMP standards for certain products. Our team of scientists are also dedicated to providing personalized services through long-term partnerships and collaborations. With commitment to quality and customer satisfaction, BioBasic Inc has the expertise and experience to help you advance your research quickly and efficiently to meet your project goals.

20 Konrad Cres. Markham, ON, L3R 8T4 BermudaSince 2004, BioBasic Inc has been a trusted partner in the life sciences industry for supporting scientific research and innovation. As a direct manufacturer, we offer a wide selection of high-quality materials, reagents and services such as DNA Sequencing, Gene Synthesis, Protein expression & Purification, Peptide Synthesis and Antibody Production. We also have the industrial capacity to provide corresponding services in bulk as well as under GMP standards for certain products. Our team of scientists are also dedicated to providing personalized services through long-term partnerships and collaborations. With commitment to quality and customer satisfaction, BioBasic Inc has the expertise and experience to help you advance your research quickly and efficiently to meet your project goals.

501 Deerhurst Drive, Suite 102, Burlington, On l7l 5T1Canadian SHIELD Ethics Review Board was formed to expedite research at private practices in Canada and the USA. The administrative staff of Canadian SHIELD has extensive experience both within the pharmaceutical industry and at the research site. The Board Administrator understands the needs of study sponsors based on more than 18 years of drug development experience and has implemented streamlined procedures to minimize the administrative burden to both the sponsor and the Investigator.

Richmond Hill, ON CanadaClinetica provides program management, study design, vendor selection, clinical monitoring, and protocol development.

Clinetica Biosciences International, Inc. 95 Mural Street, Suite 600 Richmond Hill, ON L4B 3G2Clinetica provides program management, study design, vendor selection, clinical monitoring, and protocol development.

Ottawa, ON CanadaClaigan provides environmental compliance services.

Claigan Inc. 105 Schneider Road, Suite 211 Kanata, ON K2K 1Y3, CanadaClaigan provides environmental compliance services.

Ottawa, ON CanadaChemaphor offers health and wellness products for humans and animals as well as specialty chemicals

100 Sussex Drive, Ottawa, ON K1A 0R6 CanadaChemaphor offers health and wellness products for humans and animals as well as specialty chemicals

262 The Queensway N. RR#1, Keswick, ON L4P 3C8Carter Pharmaceutical Consulting provides solid oral dosage form development, manufacturing, consulting, process optimization, and training.

270 Adam Street, Belleville (Ontario) K8N 5S4The Thermal Comfort Specialists Thanks to its 400 technicians, estimators and technical advisors, Carmichael maintains an unrivaled national leadership position in thermal system technologies. Established in 1922, the company now boasts 21 regional service centres across Canada. A team dedicated to excellence Carmichael's comprehensive range of services are industry-leading. Driven by the desire to create tailored and optimal technical solutions, our team is indispensable from the conceptual stage through to completion. Our outstanding reputation stems primarily for one of our core strengths: preventative maintenance. Carmichael specialists understand your business and can meet all of your thermal system needs, from preventative maintenance, diagnostic and repair, to design and installation. Our versatility enables us to adapt our solutions to a variety of thermal applications in diverse industries and business environments. Family Culture and Global Vision For three generations, Carmichael has nurtured passionate engineers, technicians, systems designers, and technical advisors who are dedicated to excellence. Our thoroughly experienced and multi-technical team of professionals can attain your thermal objectives and respect your constraints with ease and efficiency. Our collective goal is to support our valued clients with the very best in maintenance, design and installation.

700 Collip Circle Suite 213 London, N6G 4X8 CanadaCritical Outcome Technologies provides disease-specific drug discovery, optimization, and pre-clinical development.

2851 Brighton Rd. Oakville, ON L6H 6C9 CANADACan-Am Instruments Ltd. is a Canadian distributor of industrial process controls and a leader in providing quality environmental and laboratory instrumentation. We are an ISO 9001:2008 certified company and have been serving our valuable clients for over 45 years. Our products include waste water samplers, open channel and closed pipe flow meters, magnetic flow meters, remote wireless communications, online water analyzers, viscometers, texture analyzers, tank level controls, alarm dialers, oil in water monitors and treatment equipment, gas detection systems and various other portable and online meters. We represent the following manufacturers: Brookfield Engineering Laboratories Inc, American Sigma (a div. of the Hach Company), Hach, Highland Tank (McTighe Separators), Barnett Engineering, Arjay Engineering, Enmet Canada, FMI, ACR, MJK, Barnant, Novasina, Telog, and others.

Mississauga, ON CanadaCacheSyn offers custom synthesis for specialty products as well as a wide-selection of catalog products.

5715 Coopers Ave., Unit 5 Mississauga, ON L4Z 2C7 CanadaCacheSyn offers custom synthesis for specialty products as well as a wide-selection of catalog products.

Toronto Medical Discovery Tower 9th Floor Rm 9-305 101 College Street Toronto, Ontario, Canada M5G 1L7Center for High-Throughput Structural Biology offers high throughput screening services.

Mississauga Ontario 52 CanadaChemi Pharmaceutical offers quality control testing, natural health products, stability studies, and method development.

250 College St Toronto, , ON , M5T 1L8 CanadaThe Centre for Addiction and Mental Health (CAMH) is the leading mental health and addictions research facility in Canada, and one of the largest in the world. Research at CAMH is an integrated part of the organization. We share CAMH’s vision, mission, and values. Our research program includes: • The Campbell Family Mental Health Research Institute, with a focus on brain science • Clinical research • The Institute for Mental Health Policy Research Affiliations As a teaching hospital, all CAMH scientists hold cross-appointments with the University of Toronto. CAMH is a designated WHO/PAHO Collaborating Centre in Addictions and Mental Health.

7600 Danbro Cres Mississauga Ontario L5N 6L6 CanadaCPL-Contract Pharmaceuticals offers method development, validation, chromatography, spectrophotometry, microbial testing, and stability studies.

600 University Ave., Room 6-423 Toronto, ON M5G 1X5 CanadaClinical Genomics Centre provides a broad range of services from upstream study design and grant writing support through to downstream data analysis including genomic analysis, NGS, and bioinformatics.

2255 Sheppard Ave. East Suite E—331 Toronto, Ontario, M2J 4Y1 CanadaCrossey Engineering Ltd. is a multi-disciplined consulting engineering firm that has been in existence since 1963. Our head office is located at 2255 Sheppard Avenue East in Toronto, Ontario. We also have branch offices in Ottawa. CEL is dedicated to ensuring that buildings function efficiently – over the short and long-term – while working within the clients’ budgets, timetables and aesthetic visions. CEL consistently helps clients achieve this by creating and adapting designs in the areas of Electrical, Mechanical, Telecommunications Infrastructure and Controls. We also provide Lighting (Consullux), Sustainability design (CEL Gruen) and Commissioning Services (VSC Group).

2255 Sheppard Avenue East, Toronto, ON M2J, CACrossey Engineering Ltd. is a multi-disciplined consulting engineering firm that has been in existence since 1963. Our head office is located at 2255 Sheppard Avenue East in Toronto, Ontario. We also have branch offices in Ottawa. CEL is dedicated to ensuring that buildings function efficiently – over the short and long-term – while working within the clients’ budgets, timetables and aesthetic visions. CEL consistently helps clients achieve this by creating and adapting designs in the areas of Electrical, Mechanical, Telecommunications Infrastructure and Controls. We also provide Lighting (Consullux), Sustainability design (CEL Gruen) and Commissioning Services (VSC Group).

5295 John Lucas Drive Burlington, ON, L7L 6A8 CanadaNatrix Separations is a leading supplier of high performance, single use and multi-cycle disposable chromatography products to the life science, food, beverage and water markets.

Toronto, ON, Canada,CellaVision offers analyzers, review software, competency software, and blood smearing devices.

1980 Matheson Boulevard East Suite A Mississauga, Ontario L4W 5N3 CANADAClearstone Central Laboratories offers laboratory testing for clinical trials.

P.O Bag 1150 300 Laurier Blvd. Brockville, ON K6V 5W1 CanadaChromatographic Specialties provides gas and liquid chromatography consumables and instrumentation.

Toronto, ON CanadaCanadian Custom Packaging Company (CCP) offers custom product manufacturing, innovative product development, flexible manufacturing, competitive pricing, and strong customer support.

333 Rimrock Road Toronto, Ontario M3J 3J9 CanadaCanadian Custom Packaging Company (CCP) offers custom product manufacturing, innovative product development, flexible manufacturing, competitive pricing, and strong customer support.

6980 Creditview Rd, Mississauga, ON, L5N 8E2 CanadaCaldic is recognized as Canada’s leading food ingredient supplier, distributing a wide range of raw materials for the food and personal care market and specializing in the manufacture of antioxidants, release agents, bakery concentrates, dough conditioners and vitamin and mineral enrichment blends.

University Health Network - Toronto Western Hospital Division of Neurosurgery, 4W-423 399 Bathurst Street Toronto, Ontario M5T 2S8The Canadian Virtual Brain Tumour Bank (CVBTB) is a national brain tumour banking resource that serves to further clinical, molecular and translational research. Under sponsorship with Schering-Plough Canada and in association with the Canadian Brain Tumour Consortium (CBTC), the CVBTB was created to provide research and academic communities easier access to high quality samples across the country. An informative, user-friendly and easy-to-navigate website, the CVBTB links brain tumour sample holdings from established brain tumour banks in Canada. As a virtual bank, the CVBTB does not store actual brain tumour samples but rather acts as a central point of access allowing researchers to query specific brain tumour samples. Once queries are completed, the CVBTB helps to coordinate the delivery of samples between researchers and respective tumour banks. The CVBTB also acts as a brain tumour banking resource by providing assistance on standardized operating procedures on procedures such as tissue sample accrual, tissue sample storage, blood and lymphocyte processing and tissue sample delivery. Under the collaboration of neurooncologists, ethics advisors, neuropathologists and technicians, the CVBTB hopes to play a large role in furthering brain tumour research and to make an impact both on a national and global scale.

60 North Centre Rd. Box 27052 London, ON, N5X 3X5 CanadaCytognomix is a biotechnology company developing and selling patented software-based solutions and reagents for clinical genomics. Current products include mutation interpretation software, DNA probe reagents and companion software to detect chromosome abnormalities at the molecular level.

700 Collip Circle #150 London, Ontario N6G 4X8 CanadaCytognomix is a biotechnology company developing and selling patented software-based solutions and reagents for clinical genomics. Current products include mutation interpretation software, DNA probe reagents and companion software to detect chromosome abnormalities at the molecular level.

200 Elizabeth St Toronto, ON, M5G 2C4 Canada

134 Ner Israel Drive Vaughan, ON, L4J 9L1 Canada

200 Elizabeth Street Toronto, ON, M5G 2C4 Canada

220 Yonge Street Suite 211 Toronto, ON, M5B 2L7 CanadaCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

120 Carlton St. Suite 204 Toronto CanadaCanCog Technologies offers canine cognitive models, in vivo brain imaging, rodent neuropsychiatic models, human cognitive assessment, and neurobiological screens.

120 Carlton St -suite 204 Toronto Ontario M5A4K2 CanadaCanCog Technologies offers canine cognitive models, in vivo brain imaging, rodent neuropsychiatic models, human cognitive assessment, and neurobiological screens.

456 Sheppard Ave Pickering ON L1V 1E5 CanadaCorsidus provides ADME assays, toxicology, animal imaging, GLP drug preparation, radiolabeling, and spectrometry.

190 Harris St Rockwood, ON N0B 2K0CanBioPharma Consulting provides consultative support for nonclinical research, clinical pathology interpretation, and due diligence.

Oakville, ON CanadaCMX Research offers clinical research services including trial management, data management, patient recruitment, and regulatory submissions with expertise in urology and oncology studies.

416 North Service Road East, Level 2 Oakville, ON L6H 5R2 CanadaCMX Research offers clinical research services including trial management, data management, patient recruitment, and regulatory submissions with expertise in urology and oncology studies.

115 Skyway Ave Toronto, Ontario, M9W4Z4 CanadaCustom Biologics is Canada’s leading large molecule CRO providing custom bioassay design, validation and regulatory compliant testing. For over 10 years Custom Biologics has been designing, validating and implementing bioanalytical, ligand-binding, residual contamination and cell-based bioassays to support pre-clinical and clinical testing requirements of large and small molecules. We have extensive expertise in characterizing the functional properties of biologics, in particular biosimilars, as per ICH Q6B guidelines. A list of some of the biosimilars and supporting assays we are experienced with can be found here, http://custombiologics.com/biologics/biosimilars/ All work adheres to an exacting Quality Control System based on FDA 21 CFR, Parts 11 and 58 Guidelines.

2585 Meadowpine Blvd. Mississauga, ON L5N 8H9Custom Biologics is Canada’s leading large molecule CRO providing custom bioassay design, validation and regulatory compliant testing. For over 10 years Custom Biologics has been designing, validating and implementing bioanalytical, ligand-binding, residual contamination and cell-based bioassays to support pre-clinical and clinical testing requirements of large and small molecules. We have extensive expertise in characterizing the functional properties of biologics, in particular biosimilars, as per ICH Q6B guidelines. A list of some of the biosimilars and supporting assays we are experienced with can be found here, http://custombiologics.com/biologics/biosimilars/ All work adheres to an exacting Quality Control System based on FDA 21 CFR, Parts 11 and 58 Guidelines.

Mississauga, ON, CanadaCustom Biologics is Canada’s leading large molecule CRO providing custom bioassay design, validation and regulatory compliant testing. For over 10 years Custom Biologics has been designing, validating and implementing bioanalytical, ligand-binding, residual contamination and cell-based bioassays to support pre-clinical and clinical testing requirements of large and small molecules. We have extensive expertise in characterizing the functional properties of biologics, in particular biosimilars, as per ICH Q6B guidelines. A list of some of the biosimilars and supporting assays we are experienced with can be found here, http://custombiologics.com/biologics/biosimilars/ All work adheres to an exacting Quality Control System based on FDA 21 CFR, Parts 11 and 58 Guidelines.

Toronto, ON CanadaCENTUVA provides efficient and cost-effective MD and PhD contract services right across the industry. Our experienced team of MDs and PhDs work with Marketing/Sales and Medical Affairs departments across North America and Europe. We work on demand with pharmaceutical, medical device and medical diagnostics companies through a personalized approach. We offer several services including our award-winning Doctors Speaking With Doctors. See our service offer at www.centuva.com. Centuva’s unparalleled access to the medical community, expertise, value and credibility lets you target your markets, build ongoing dialogue and achieve your goals.

7398 Yonge St Thornhill, Ontario, L4J 8J2 CanadaConcinto is a Canadian consulting firm with global experience focused on education, R&D, and commercialization in life sciences. We founded Concinto to present a new approach toward education and commercialization. We believe that the education and commercialization practices should be designed and delivered based on new drivers in the healthcare ecosystem. At Concinto, we design evidence-based strategies to pinpoint business opportunities and efficiently deliver relevant services and communications. We also utilize our clinical research and product development expertise to introduce novel products in targeted therapeutic areas to address unmet needs. We help our clients to optimize their operations and services for the new digital economy. Concinto offers new commercialization strategies and online education and communications to keep companies competitive in this new environment. Concinto is an accredited continuing education provider by the Canadian Council on Continuing Education in Pharmacy (CCCEP).

7398 Yonge St Thornhill, Ontario, L4J 8J2 CanadaConcinto is a Canadian consulting firm with global experience focused on education, R&D, and commercialization in life sciences. We founded Concinto to present a new approach toward education and commercialization. We believe that the education and commercialization practices should be designed and delivered based on new drivers in the healthcare ecosystem. At Concinto, we design evidence-based strategies to pinpoint business opportunities and efficiently deliver relevant services and communications. We also utilize our clinical research and product development expertise to introduce novel products in targeted therapeutic areas to address unmet needs. We help our clients to optimize their operations and services for the new digital economy. Concinto offers new commercialization strategies and online education and communications to keep companies competitive in this new environment. Concinto is an accredited continuing education provider by the Canadian Council on Continuing Education in Pharmacy (CCCEP).

919 Fraser Drive Unit 11 Burlington, ON, L7L 4X8 CanadaCytodiagnostics supplies reagents and secondary antibodies while offering custom conjugation services for nanoparticles and dyes.

204-3228 South Service Rd Burlington, ON, L7N 3H8 CanadaThe Value & Evidence team (formerly Cornerstone Research Group) at EVERSANA, is a dynamic 100+-person team with small company DNA and large company opportunities. Our work is focused on identifying, demonstrating, and communicating the value of pharmaceutical, biotechnology, and medical device. We offer innovative health economic, health outcomes, market access and data analytic services. We pride ourselves on high-quality work that has been published in a wide range of peer-reviewed journals. Our reputation is for strategic thinking that results in high quality research that meets the needs of our clients, payers, and health technology assessment and regulatory agencies.

500 Palladium Drive Suite 3000 Ottawa, ON, K2V 1C2 CanadaDNA Genotek, a subsidiary of OraSure Technologies, Inc., focuses on providing high-quality biological sample collection products and end-to-end services for human genomics, microbiome and infectious disease applications. The Company's Oragene•Dx and ORAcollect•Dx product lines are the first and only FDA 510(k) cleared saliva-based DNA collection devices for in vitro diagnostic use. DNA Genotek also offers Research Use Only products to collect and preserve large amounts of DNA or RNA from multiple sample types. DNA Genotek markets its products worldwide and has a global customer base with thousands of customers in over 100 countries. DNA Genotek offers comprehensive services for both genomic and microbiome sample types including processing, sequencing and bioinformatics analysis. Through the acquisition of CoreBiome - a microbiome analysis company focused on accelerating discovery for customers in medical, pharmaceutical, agricultural and academic research - DNA Genotek offers comprehensive services for microbiome sample processing, sequencing, and bioinformatic analysis. CoreBiome offers microbial profiling of all sample types, including the complete line of DNA Genotek’s OMNIgene® collection devices as well as a broad range of high, medium and low microbial biomass sample types. Contact us today to learn more about our collection devices, laboratory and fulfillment services. https://dnagenotek.com

Oakville, ON Canadadsa consultants provides regulatory affair services for drugs, medical devices, natural health products and cosmetics.

1620 Tech Avenue Unit 3 Mississauga, ON L4W 5P4 CanadaDiteba Research Laboratories offers laboratory testing services including assay development and validation, quality control release testing, bioanalytical testing services, bioassays and feasibility testing.

1620 Tech Avenue Unit 3 Mississauga, ON L4W 5P4 CanadaDiteba Research Laboratories offers laboratory testing services including assay development and validation, quality control release testing, bioanalytical testing services, bioassays and feasibility testing.

288 Canterbury Dr Canada Waterloo, ON, N2K 3C1 CanadaWe are focused on building the best software. We work with clients to create a solution that best fits their company and customers. ENTERPRISE SOFTWARE We specialize in software development for scientific, healthcare and business applications. We translate your business requirements into solutions ranging from desktop to multi-tier client-server platforms. WEB APPLICATIONS We deliver full stack web applications that are rich in functionality, elegant and visually compelling. Our apps are designed to also work great on mobile and tablet devices. MOBILE DEVELOPMENT We develop mobile applications for the public or enterprise. Development using hybrid technologies offers the fastest and most affordable way to build solutions for multiple mobile platforms. PROCESS IMPROVEMENT We help your team improve processes to enhance flexibility, quality and confidence in the code. Implementing an Agile process can significantly reduce risks and time to initial revenue. PBPK MODELLING We provide interspecies and intraspecies (pediatric, renal/hepatic impairment) pharmacokinetic extrapolation. Dose determination in young patients for pediatric clinical trial planning is our specialty. PBPK TRAINING Our training emphasizes both the fundamental aspects of PBPK modeling, as well as application. Application examples include pediatric, other special populations (genetic, impairment), metabolite modeling and dynamic DDI prediction.

7 St. Thomas Street Suite 603 Toronto, Ontario, M5S 2B7 Canadadicentra is a full-service CRO serving the nutraceutical, dietary supplement, and functional food industries. Our research facility and welcoming clinic are located in Yorkville, downtown Toronto giving us unparalleled access to a large and diverse pool of research populations. Since our inception in 2002, we have completed over 18,000 projects and serviced over 1,200 companies internationally.

349 Wildcat Rd North York, ON, M3J 2S3 CanadaDalton Pharma Services, part of Seikagaku Corporation- Tokyo, Japan, is a leading cGMP Manufacturing Facility, providing integrated drug discovery services as well as pharmaceutical development and manufacturing services to the pharmaceutical and biotechnology industries. We are FDA Inspected and Health Canada approved and bring over 35 years of experience to every project. We can accelerate your Drug Discovery and Development Program by integrating process development, API manufacturing, and finish dose manufacturing all at a single location. We provide a full range of services from Discovery and Development to Manufacturing: cGMP Sterile Filling Services cGMP API Manufacturing Services API Process Development Formulation Development Services Custom Synthesis Flow Chemistry Conjugation Custom Peptide Synthesis cGMP Oligonucleotide Fill Contract Analytical Services Contract Research Services Medicinal Chemistry Services Polymorphic Screening Project Management

2820 Argentia Road Suite 8-9 Mississauga, ON, L4G 8H9 CanadaDalriada’s Turn-Key Drug Discovery model is specifically designed to provide ultimate support for semi-virtual lean biotechs developing small molecule therapies. We uniquely integrate internal R&D, end-to-end program management, business and IP support to unlock the most rapid and agile program execution and ultimately the fastest route to the clinic. ​ We focus on value building for each client and partner and conduct all programs with an R&D-to-milestone approach. Drawing experience from Pharma, Biotech, VC, and Academia, Dalriada’s team equally understands both the science and business needs, which allows for a seamless collaboration with the biotech client or a fully autonomous project execution.

4200 S Service Road Burlington, Ontario, L7L 4X5 CanadaElarex is a Canadian healthcare technology company commercializing its proprietary PT120 formulation technology which has proven to stabilize biologicals (including live vaccines!) so that they are as effective when stored at 40C as if they had been stored at -80C.

Zone 5, Southwestern Ontario, CanadaEcologistics Research Services (ERS) is an agricultural and horticultural contract research facility that conducts GLP (Good Laboratory Practice) and non-GLP studies for both public and private clients. Our goal is to provide the agricultural industry with a comprehensive range of friendly, precise, reliable and innovative research, consulting and development services.

98 Walker Drive Brampton, ON, L6T 4H6 Canada

6 Clark St. St. Catharines, Ontario L2R5G2 CanadaEntomogen offers environmental consulting, insect identification, tick identification, and viral testing for mosquito and tick borne diseases.

244 October Crescent London, Ontario, N6K 4W5 CanadaEndpoint Preclinical specializes in connecting CROs, pharma, medical device and academic labs with our network of Research Specialists for various project-based needs; including surgical procedures, data collection/analysis, report generation and in-lab training. Our experts include radiologists, former CRO directors/owners, sonographers, board certified veterinary cardiologists, emeritus professors, and more. Our model allows labs to access specialized services without the need for full-time staff, streamlining operations and reducing costs. Among our services, we offer: Remote echocardiography data analysis (handling up to 6000 scans annually). Remote radiological data review and interpretation from MRI, PET/CT, PET/MRI, etc. Pressure-Volume loop data collection/analysis, including equipment rental. GLP and non-GLP ECG analysis for discovery, efficacy, safety pharmacology, toxicology, and biostatistics. Over 25 different cardiovascular surgical procedures, including disease model development. Comprehensive training programs for surgical procedures, data collection, and analysis.

244 October Crescent London, Ontario, N6K 4W5 CanadaEndpoint Preclinical specializes in connecting CROs, pharma, medical device and academic labs with our network of Research Specialists for various project-based needs; including surgical procedures, data collection/analysis, report generation and in-lab training. Our experts include radiologists, former CRO directors/owners, sonographers, board certified veterinary cardiologists, emeritus professors, and more. Our model allows labs to access specialized services without the need for full-time staff, streamlining operations and reducing costs. Among our services, we offer: Remote echocardiography data analysis (handling up to 6000 scans annually). Remote radiological data review and interpretation from MRI, PET/CT, PET/MRI, etc. Pressure-Volume loop data collection/analysis, including equipment rental. GLP and non-GLP ECG analysis for discovery, efficacy, safety pharmacology, toxicology, and biostatistics. Over 25 different cardiovascular surgical procedures, including disease model development. Comprehensive training programs for surgical procedures, data collection, and analysis.

6800 Campobello Road Mississauga Ontario Canada L5N 2L8EBPI Environmental Bio-Detection Products offers Ames testing, genotoxicity testing, mutation analysis products and services.

Stiller Centre, 4M3 700 Collip Cir London, ON, N6G 4C4 CanadaExpert Synthesis Solutions (ESS) is a research and development company specializing in low volume, high value organic synthesis of complex small molecules.

2395 Speakman Drive Mississauga, ON, L5K 1B3 CanadaElement’s Health Sciences Division offers consulting and analytical testing solutions for the pharmaceutical, medical device and biotech industries. Our facilities operate under GLP/GMP. We provide a wide range of CMC development services and clinical manufacturing (Phase I & II) for IND/NDA/ANDA drug products, specializing in parenteral, topical and ophthalmic products. We have an established expertise in method development & validation, harmonized compendia testing, E&L programs for manufacturing equipment, transdermal, inhalation, injectable, and combination medical device products. Our goal is to offer comprehensive solutions tailored for successful product approvals. Our relationships are built on expertise, partnerships and trust.

2884 Portland Drive Oakville, ON , L6H 5W8 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, is a leading provider of Active Pharmaceutical Ingredient and Drug Product development and manufacturing services for complex small molecules, including highly potent compounds. As a campus style facility, we offer API and Drug Product Development services as a fully integrated solution or as stand-alone services.

2240 Speakman Drive Mississauga, Ontario, L5K 1A9 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, is a leading provider of Active Pharmaceutical Ingredient and Drug Product development and manufacturing services for complex small molecules, including highly potent compounds. As a campus style facility, we offer API and Drug Product Development services as a fully integrated solution or as stand-alone services.

2884 Portland Drive Oakville, ON, L6H 5W8 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, is a leading provider of Active Pharmaceutical Ingredient and Drug Product development and manufacturing services for complex small molecules, including highly potent compounds. As a campus style facility, we offer API and Drug Product Development services as a fully integrated solution or as stand-alone services.

2395 Speakman Drive Mississauga Ontario L5K1B3 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, is a leading provider of Active Pharmaceutical Ingredient and Drug Product development and manufacturing services for complex small molecules, including highly potent compounds. As a campus style facility, we offer API and Drug Product Development services as a fully integrated solution or as stand-alone services.

2395 Speakman Drive, suite 2001 Mississauga, Ontario, L5K1B3 CanadaEurofins CDMO Alphora Inc., operating as part of Eurofins CDMO, is a leading provider of Active Pharmaceutical Ingredient and Drug Product development and manufacturing services for complex small molecules, including highly potent compounds. As a campus style facility, we offer API and Drug Product Development services as a fully integrated solution or as stand-alone services.

555 University Avenue Toronto, Ontario, M5G 1X8 CanadaThe Hospital for Sick Children (SickKids), affiliated with the University of Toronto, is Canada's most research-intensive hospital and the largest centre dedicated to improving children's health in the country. As innovators in child health, SickKids improves the health of children by integrating care, research and teaching. With a staff that includes professionals from all disciplines of health care and research, SickKids provides the best in complex and specialized care by creating scientific and clinical advancements, sharing knowledge and expertise and championing the development of an accessible, comprehensive and sustainable child health system.

400 Britannia Road East. Unit 1 Mississauga, Ontario L4Z 1X9 CanadaHach Company manufactures and distributes analytical instruments and reagents used to test the quality of water and other liquids.

Burlington, Ontario, CanadaFermentas International, now part of Thermo Fisher Scientific, provides enzymes, DNA services, electrophoresis products, and reagents.

4975 Rideau Street, Suite 100 Industrial Park Quebec, Qc, Canada G2E 5H5Feldan Bio offers mammalian cell culture, cytotoxicity assay, recombinant proteins, antibodies, viruses, stem cells, permeability assay, chromatography and purification services.

PO Box 21422 Toronto, Ontario, M5T 0A1 CanadaFlowJEM technology was developed for research and development projects by microfluidic researchers and engineers like you. Our goal is to meet the demands for high quality, fast turnaround time and low cost. Work with us to develop your ideas into prototypes or transition your prototypes to volume production. FlowJEM's innovative manufacturing process allows us to prototype your designs in an economical way. This ensures that your vision is brought to life, unhindered by the limitations of standard designs offered by other companies. In the meanwhile, we provide versatile services and have access to multiple facilities, which can meet different needs.

80 Saint George Street Toronto, ON, M5S 3H4 CanadaFlowJEM technology was developed for research and development projects by microfluidic researchers and engineers like you. Our goal is to meet the demands for high quality, fast turnaround time and low cost. Work with us to develop your ideas into prototypes or transition your prototypes to volume production. FlowJEM's innovative manufacturing process allows us to prototype your designs in an economical way. This ensures that your vision is brought to life, unhindered by the limitations of standard designs offered by other companies. In the meanwhile, we provide versatile services and have access to multiple facilities, which can meet different needs.

3080 Yonge Street Suite 6100, Box 66 Toronto, Ontario, Canada M4N 3N1FujiFilm VisualSonics Inc. is a manufacturer of real-time, in vivo, high-resolution micro-imaging systems designed specifically for preclinical research and is a wholly owned subsidiary of SonoSite, Inc. VisualSonics’ imaging technologies allow researchers at pharmaceutical and biotechnology companies, hospitals and universities to conduct research in cardiovascular, cancer, neurobiology and developmental biology areas. The micro-imaging technologies support research applications that include genetic research, phenotypic studies and drug development. VisualSonics high-frequency micro-imaging and photoacoustic platforms combine high-resolution, real-time in vivo imaging with quantifiable data that have been published in over 850 scientific publications globally.

3080 Yonge Street Suite 6100, Box 66 Toronto, ON, M4N 3N1 CanadaFujiFilm VisualSonics Inc. is a manufacturer of real-time, in vivo, high-resolution micro-imaging systems designed specifically for preclinical research and is a wholly owned subsidiary of SonoSite, Inc. VisualSonics’ imaging technologies allow researchers at pharmaceutical and biotechnology companies, hospitals and universities to conduct research in cardiovascular, cancer, neurobiology and developmental biology areas. The micro-imaging technologies support research applications that include genetic research, phenotypic studies and drug development. VisualSonics high-frequency micro-imaging and photoacoustic platforms combine high-resolution, real-time in vivo imaging with quantifiable data that have been published in over 850 scientific publications globally.

2916 South Sheridan Way Oakville, ON, L6J 7J8 CanadaFor over 40 years we've been serving our clients by freeze drying food ingredients and other specialty products. Our customers include many of the world's leading food companies and other specialty processors. With our fully equipped laboratory we are able to help customers develop the products they need. We can also show you how freeze dried ingredients can have a very positive impact on your product's quality. WHY CHOOSE US Real people, real connections Our commitment to excellence in customer service is built into the way we manage our business. We connect with you on a person-to-person level giving you immediate access to expertise and solutions throughout our organization. We believe this approach makes our customer service the best in the industry. We listen to you Consult with us about your unique requirements for products and processes. We will work with you to create a solution including special formulations, custom pre-and post-drying services, and a variety of packaging requirements. Confidentiality is assured.

RR#3, 6570 1st Line West Garafraxa Fergus, ON N1M 2W4Gallus Immunotech offers peptide synthesis, antibody production, antibody purification, and antibody labeling services.

565 Edward Avenue Richmond Hill, ON, L4C 9W8 CanadaGeneral Ingredient is a supplier of nutritional raw materials to the nutraceutical, food additive, health and sports nutrition industries.

115 Midair Court Brampton, Ontario, L6T 5M3 CanadaGamma-Dynacare Medical Laboratories offers diagnostic assays and clinical trial services.

1456 Wallace Road, Unit 1 Oakville Ontario L6L 2Y2 CanadaGL Chemtec International is a contract manufacturing organization, specializing in the custom synthesis of complex molecules.

945 Princess St. Ste. 105 Kingston, Ontario, K7L 0E9 CanadaGreenCentre Canada offers unique chemistry Innovation Services to help companies meet their research needs and adds value across the entire development chain. We work collaboratively with our partners to de-risk early stage technologies and accelerate commercialization.

945 Princess St Kingston, ON, K7L CanadaGreenCentre Canada offers unique chemistry Innovation Services to help companies meet their research needs and adds value across the entire development chain. We work collaboratively with our partners to de-risk early stage technologies and accelerate commercialization.

2150 Islington Avenue, Suite 201 Toronto, Ontario M9P 3V4 CanadaHealthDiary is a technology partner in clinical research and health studies, offering patient diary solutions also known as electronic Patient Reported Outcomes (ePRO), Electronic Data Capture (EDC) and patient registries. HealthDiary is cloud based and designed to collect data, manage, and monitor multi-centre, multi-language studies.

2150 Islington Ave #201 Etobicoke, ON, M9P 3V4 CanadaHealthDiary is a technology partner in clinical research and health studies, offering patient diary solutions also known as electronic Patient Reported Outcomes (ePRO), Electronic Data Capture (EDC) and patient registries. HealthDiary is cloud based and designed to collect data, manage, and monitor multi-centre, multi-language studies.

Bowmanville, ON CanadaHolburn provides research consulting, clinical trial services, and management services.

1200 Main Street West Hamilton, ON, L8N 3Z5 CanadaHamilton Health Sciences is a family of seven unique hospitals, a cancer centre and an urgent care centre, serving more than 2.3 million residents of Hamilton and south central Ontario, Canada. Hamilton Health Sciences is the second largest hospital group in Ontario, and serves as a regional referral centre for cardiac, stroke, burns, trauma, neurosurgery, pediatrics, digestive diseases, high-risk obstetrics, cancer, orthopedics and rehabilitation services. With a staff of approximately 11,000, the hospital is the largest employer in the Hamilton region. As an academic teaching hospital with more than 1,100 beds and an affiliation with McMaster University and Mohawk College, Hamilton Health Sciences is committed to providing exemplary health care while advancing excellence in education and health research. The organization’s exceptional track record of inquiry and innovation has earned Hamilton Health Sciences recognition as one of the world’s leading health science research organizations. Staff of Hamilton Health Sciences share a commitment to providing the best possible care to our patients and their families. Guided by our values of respect, caring, innovation and accountability, Hamilton Health Sciences is focused on uniting the best health care has to offer and ensuring our patients have access to the type of care they need when they need it most. The breadth and scope of services offered by HHS, in combination with the hospital's focus on academics and research, make it an employer of choice for many people. Physicians, nurses and clinicians find it attractive to work in HHS' diverse environment where they can be part of a health care team focused on providing the best possible care to patients and their families. Non-medical professionals enjoy bringing their varied talents and skills to a field where priorities are driven by care, not profit.

1200 Main St. West Hamilton, Ontario, Canada L8N 3Z5Hamilton Health Sciences is a family of seven unique hospitals, a cancer centre and an urgent care centre, serving more than 2.3 million residents of Hamilton and south central Ontario, Canada. Hamilton Health Sciences is the second largest hospital group in Ontario, and serves as a regional referral centre for cardiac, stroke, burns, trauma, neurosurgery, pediatrics, digestive diseases, high-risk obstetrics, cancer, orthopedics and rehabilitation services. With a staff of approximately 11,000, the hospital is the largest employer in the Hamilton region. As an academic teaching hospital with more than 1,100 beds and an affiliation with McMaster University and Mohawk College, Hamilton Health Sciences is committed to providing exemplary health care while advancing excellence in education and health research. The organization’s exceptional track record of inquiry and innovation has earned Hamilton Health Sciences recognition as one of the world’s leading health science research organizations. Staff of Hamilton Health Sciences share a commitment to providing the best possible care to our patients and their families. Guided by our values of respect, caring, innovation and accountability, Hamilton Health Sciences is focused on uniting the best health care has to offer and ensuring our patients have access to the type of care they need when they need it most. The breadth and scope of services offered by HHS, in combination with the hospital's focus on academics and research, make it an employer of choice for many people. Physicians, nurses and clinicians find it attractive to work in HHS' diverse environment where they can be part of a health care team focused on providing the best possible care to patients and their families. Non-medical professionals enjoy bringing their varied talents and skills to a field where priorities are driven by care, not profit.

Toronto, ON, CanadaHealthGene Corp offers DNA extraction services, particularly for animals.

2175 Keele St. Toronto, ON M6M 3Z4 CanadaHealthGene Corp offers DNA extraction services, particularly for animals.

Toronto, ON CanadaHealthGene Corp offers DNA extraction services, particularly for animals.

Hamilton, ON CanadaHemostasis Reference Laboratory offers coagulation analysis, DNA analysis, cytokine screening, and blood screening tests.

30 Worcester Road Toronto, Ontario Canada M9W 5X2Intellipharmaceutics provides life cycle management and the enhancement of new chemical entities (NCEs).

Toronto, ON CanadaIntellipharmaceutics provides life cycle management and the enhancement of new chemical entities (NCEs).

188 Greenlees Drive Kingston, ON K7K 6P6 CanadaImproved Outcomes Software provides development, project management and data analysis services in the image guided surgery, bioinformatics and IT industries and sell software products.

101 College Street Toronto, ON, M5G 1L7 CanadaIn July 2005, Interface Biologics moved into Toronto’s acclaimed MaRS Innovation Centre---a collaborative facility dedicated to accelerating emerging technologies, located near the University of Toronto campus and seven specialty hospitals.

Head Office, University Research Park 100 Collip Circle, Unit 117 London, ON N6G 4X8 CanadaID Labs supplies antibodies and detection kits for flow cytometry, DNA purification kits, and proteins in addition to offering custom oligo synthesis.

53 Romano Crescent Woodbridge, ON L4N 7N2 CanadaInnovaTox provides pharmaceutical development and environmental health assessments.

Toronto, ON CanadaInnovaTox provides pharmaceutical development and environmental health assessments.

McMaster University Health Science Centre 4H31 1280 Main Street West Hamilton, Ontario L8S 4K1

Mississaga, Ontario, CanadaIBI Biosolutions offers ligand docking, in silico drug design, molecular modeling, epitope development, sequence analysis, biostatistics and cheminformatic services.

Burlington, Ontario, CanadaIMMCO Diagnostics provides histology, serology, genetics, assay development, and pathology.

288 Wildcat Road, Toronto, ON, M3J 2N5 CanadaIBL International offers reagents, antibodies, and assay kit products for purchase.

933 Jasper Crt Kingston, ON, K7P 2A4 CanadaJV AgroBiotech is a specialized Contract Research Organization (CRO) for plant biotechnology and a manufacturer of innovative products for lawn & garden, hydroponic and agriculture applications. JV AgroBiotech provides research services to conduct focussed research trials in greenhouses and small plots to evaluate efficacy of soil supplements, fertilizers, inoculants, seed treatments, PGRs and novel innovative products ready for market entry. Efficacy studies include evaluation of changes in plant growth and development, crop yield or adaptation to the environment.

110 Main Street 5 Huntsville, Ontario P1H 1K6Kriger Research Group International offers clinical monitoring, regulatory affairs, clinical trial management, quality assurance, data management, and phase II to phase IV clinical research services.

Suite 1440, One London Place 255 Queens Avenue, London ON Canada N6A 5R8KGK Synergize provides preclinical studies, clinical trials, in vivo and vitro services, and consulting.

101 MacIntosh Boulevard Concord, Ontario Canada L4K 4R5KIK Custom Products is a full service manufacturer of aerosols, liquids and solids

268 Grosvenor Street, London, Ontario, Canada N6A 4V2Lawson Imaging of the Lawson Health Research Institute is a recognized leader in non-invasive biomedical imaging with new developments in hybrid imaging platforms such as PET/CT, SPECT/CT and MR/PET currently being applied to the areas of cardiology, neurology (including mental health), metabolic disease and cancer. Newly-acquired cyclotron and radiochemistry facilities will provide key resources for this research. Also at the forefront of biomedical imaging are the emerging technologies of photoacoustic and optical imaging and optical spectroscopy as well as the investigation and therapeutic application of bioelectromagnetics. As a world leader using state-of-the-art imaging technology, our research is focused on the development of non-invasive capabilities and diagnostic imaging so that we can better understand the fundamental mechanisms of human biology and enhance the diagnosis, prevention and treatment of disease.

857 Grand Ave W Suites 104,106 Chatham, ON

955 Oliver Rd Thunder Bay, ON, P7B 5E1 CanadaDynamic, modern, and highly learner-centred, we acknowledge all of our students as valued leaders of tomorrow, whose education and success are most paramount to our institution. Both campuses in Thunder Bay and Orillia promise the total university experience: a blend of academic excellence and opportunity with a rich variety of social and recreational activities. We also promise excellence in research; Lakehead is the proud host to nine Canada Research Chairs and revolutionary facilities such as our world-renowned Paleo-DNA Laboratory and our Biorefining Research Institute.

170 Shields Ct., Unit 2 Markham, Ontario Canada L3R9T5

150 Research Lane, Unit 100 University of Guelph Research Park Centre Guelph, ON N1G 4T2 CanadaLipid Analytical Laboratories (LAL) offers analysis on various lipids and fatty acid components in biological materials.

1151 Richmond Street North London, ON, N6A 5B7, CANADAThe London Regional Genomics Centre is a Robarts Research Institute led initiative and has been established through generous support from the Robarts Research Institute, The Schulich School of Medicine and Dentistry at the University of Western Ontario, London Health Sciences Centre, Child Health Research Institute and The London Regional Cancer Program. The facility provides services on a fee-for-service/cost recovery basis and offers Affymetrix GeneChip technologies and NGS services on the Ion Torrent and MiSeq platforms.

620 Colborne St., Suite 301 London, Ontario, Canada N6B 3R9A critical component of brain tumour research To aid researchers, the Brain Tumour Tissue Bank provides brain tumour samples from patients and matches clinical data for neuro-oncology research conducted in Canada and around the world. The Brain Tumour Tissue Bank was founded in 1991 and is located in the London Health Sciences Centre in London, Ontario Interested researchers can review the information found here and can contact the tissue bank for information about what is currently available. In order to complete a request, an application must be completed. ""The BTTB is an outstanding and necessary resource for the Canadian Brain Tumour Community. It is only with ongoing support from the BTFC that it will continue to flourish. I will continue to use and support the BTTB on a cost recovery basis and recommend the tumour bank to other Canadian neuro-oncology researchers, especially those with few if any local options to procure brain tumour tissues."

Toronto, ON CanadaLallemand provides yeast and bacteria development and production services.

661 University Ave, Suite 1300 Toronto, Ontario, M5G 0B7 CanadaMediphage Bioceuticals is a spin-off from the University of Waterloo. Mediphage is a non-viral gene therapy company located at JLabs in Toronto, Canada. Our proprietary core technology, ministring DNA (msDNA), is a novel non-viral vector that is designed to overcome critical challenges facing viral gene therapies and leverage advancements of non-viral gene therapy technologies. Leveraging the versatility of our msDNA non-viral technology, we are developing innovative solutions to the challenges faced with genetic and infectious diseases that have limited, or no, treatment options available at present.

1A Dixie Avenue, Niagara-on-the-Lake ON L0S 1J0 CanadaLife Chemicals is a major producer and supplier of HTS compounds and a well-recognized provider of custom synthesis and computational chemistry services to pharmaceutical, biotech, crop science companies, and academic institutions across the globe. Developing its business development Life Chemicals has associated and headquartered a family of R&D chemical companies, namely I.F. Lab, Spoluka, Life Chemicals Inc., Life Chemicals USA (Woodbridge, CT), and Life Chemicals Europe (Munich, Germany), to operate as an integral whole where every single company is focused on its individual range of products and services and, at the same time, all are motivated by achieving their common goal. Today Life Chemicals is a fully integrated platform for early drug discovery, providing complete range of contract research and contract manufacturing services. Our broad experience in synthetic organic chemistry and up-to-date equipment ensure high quality services in custom synthesis of drug-like compounds and advanced Building Blocks in mg to multiKG quantities, design and synthesis of combinatorial libraries, route scouting and production scale-up. Our expertise in computational chemistry and employment of versatile in silico techniques, such as similarity and pharmacophore search, molecular descriptors analysis, docking screening and protein modeling, enable careful design of Fragment collections, Targeted and Focused libraries and customized sets of compounds. Our keen understanding of drug discovery process with computer-assisted approaches, our knowledge of medicinal chemistry and our solid scientific background supported with a powerful production infrastructure allow us to provide efficient solutions for R&D programs of our customers, including hit-to-lead and lead optimization, improvement of drug potency, selectivity and ADMET, development of QSAR models and medchem design.

20 Martin Ross Ave Toronto, Ontario, M3J 2K8 CanadaLGC is a global manufacturer and distributor of high-quality certified reference materials, research chemicals (TRC), genomics solutions, proficiency testing, and analytical testing services. We employ our 180 years of scientific heritage, cutting-edge expertise in measurement science and track record of innovation to progress research & development and improve outcomes across pharmaceuticals, diagnostics, food, environment, industry and consumer products. Our products and services stand out, producing to the highest quality, continually adapting to changing regulation, and providing expert support and documentation to help ensure the accuracy of your analytical results. LGC. Science for a safer world. We serve as the UK’s National Measurement Institute for chemical and bioanalytical measurements. Meet our brands: - TRC TRC offers 150,000+ research chemicals, with a large inventory readily available globally. Discover our wide range of bioactive small molecules, stable isotope labelled & controlled substances to advance your research. - AXIO Proficiency Testing AXIO Proficiency Testing is a global provider of proficiency testing schemes. We support over 13,000 laboratories, with over 2,700 proficiency tests, in over 165 countries worldwide, to meet their regulatory and accreditation requirements. - Dr Ehrenstorfer Dr Ehrenstorfer provides a comprehensive range of high-quality reference materials. Over 50% of the portfolio is accredited to ISO 17034, with 14,000+ reference materials available. - LGC Industrial LGC Industrial offers innovative & agile measurement tools for a safe global infrastructure. Combining VHG, ARMI, MBH & Paragon Scientific, we deliver a wide range of petrochemical, metal, mining, powder & physical reference materials. - Mikromol Mikromol offers a portfolio of 7,000+ high-quality accredited pharmaceutical API, impurity & excipient reference standards, >95% ready to ship alongside market leading COAs. We also provide RMs management services & custom manufacturing. - Clinical Diagnostics LGC Clinical Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions, biological and reagent component materials for the extended life sciences industry. - LGC Genomics LGC Genomics offers a custom DNA sequencing service. It is comprised of Biosearch Technologies & LGC Axolabs. i) Biosearch Technologies offers GMP and RUO Oligonucleotides, Molecular biology reagents, NGS kits and enzymes, Oligo synthesis reagents and instruments, PCR reagents and instruments, and sample prep reagents and instruments. ii) LGC Axolabs offers a unique services portfolio for the development of nucleic acid therapeutics and nucleic acid-based medicines.

70 EastBeaver Creek Road #39, Richmond Hill, Toronto Ontario, Canada L4B 3B2Molcan Corporation is involved in design, research, development and production of fine chemicals, API related compounds, impurities, intermediates, metabolites, internal standards etc. using chemical synthesis and bio-fermentation processes. Our strengths in microbial fermentation, organic synthesis and natural products chemistry allow us to bring thousands of niche molecules from laboratory to the market place in relatively short period of time. Our R&D and production facilities are well equipped with modern instrumentation and over 100,000 L of reactor capacity which are supported with experienced scientific, engineering and quality assurance teams. Our clients include research-based multinational pharmaceutical companies, biotech companies, generic pharmaceutical manufacturers, natural health products and nutraceutical manufacturers, government and independent testing laboratories, universities and research institutions, cosmetic formulators, contract research organizations and contract manufacturers, etc. Our products are supplied for R&D or industrial use, not intended for human or animal use, unless otherwise mentioned.

6303 Airport Road, Suite 500 Mississauga, ON L4V 1R8 CANADAMerge Healthcare specializes in clinical systems and offers cloud-based solutions for imaging and data analytics.

615 Kumpf Drive Waterloo, ON N2V 1K8 CanadaMaplesoft’s core technologies include the world’s most advanced symbolic computation engine and revolutionary physical modeling techniques. Combined together, these technologies enable the creation of cutting-edge tools for design, modeling, and high-performance simulation.

ON CanadaMediprobe provides study design, case report forms, clinical trials, pharmacokinetic trials and ships plasma samples.

645 Windermere Road London, Ontario Canada N5X 2P1Mediprobe provides study design, case report forms, clinical trials, pharmacokinetic trials and ships plasma samples.

1151 Gorham Street, Unit #8 Newmarket, Ontario Canada L3Y 8Y1McCarthy Consulting Services provides consulting for drugs, biologics, medical devices, foods and cosmetics.

265 Watline AvenueMicrobix Biosystems provides antigens, adenovirus solutions, and contract manufacturing.

Mississauga, ON CanadaMicrobix Biosystems provides antigens, adenovirus solutions, and contract manufacturing.

101 Holiday Inn Drive / #21905 Hespeler Cambridge, ON N3C 0E6

100 College Street, University of Toronto Toronto, ON M5G 1L5, CAMitacs is a national, not-for-profit organization that has designed and delivered research and training programs in Canada for 15 years. Working with 60 universities, thousands of companies, and both federal and provincial governments, we build partnerships that support industrial and social innovation in Canada. Mitacs was founded in 1999 as a Canadian Network of Centres of Excellence, dedicated to supporting applied and industrial research in mathematical sciences and associated disciplines. In 2003, we launched a research internship program designed to increase deployment of highly educated graduates into the private sector. Open to all disciplines since 2007, Mitacs has expanded in response to industrial and university needs, including programs in R&D management, professional skills development, and international research training. Fully independent since 2011, Mitacs remains committed to its core vision of supporting research-based innovation and continues to work closely with its partners in industry, academia, and government. From aerospace systems to childhood literacy rates, Mitacs-funded research helps to strengthen connections, improve economic performance, and create jobs. Over the past 15 years, we have supported more than 10,000 research internships, trained more than 19,000 student and postdoc career-skills participants, and supported more than 1,300 international research collaborations.

109 Railside Road, Suite 305, Toronto, Ontario M3A 1B2, CANADAMightex Systems, with operations based in Toronto, Canada, and in the Silicon Valley, California, is a leading supplier of photonic products and services for a broad spectrum of applications including industrial imaging, bio-photonic solutions, LED illumination, machine vision, life & health sciences, and industrial test & measurement etc. OEM Services: With a world-class OEM design team, Mightex offers a broad range of customized solutions in order to meet individual customer’s unique requirements. At Mightex, our mission is to provide you - our customers - with high quality solution at low cost and in a timely fashion. Our engineering team will partner with you to create “total solutions” to fit your requirements.

1241 Railside Road, Suite 305 Toronto, Ontario, M3A 1B2 CanadaMightex Systems, with operations based in Toronto, Canada, and in the Silicon Valley, California, is a leading supplier of photonic products and services for a broad spectrum of applications including industrial imaging, bio-photonic solutions, LED illumination, machine vision, life & health sciences, and industrial test & measurement etc. OEM Services: With a world-class OEM design team, Mightex offers a broad range of customized solutions in order to meet individual customer’s unique requirements. At Mightex, our mission is to provide you - our customers - with high quality solution at low cost and in a timely fashion. Our engineering team will partner with you to create “total solutions” to fit your requirements.

789 Don Mills Road, Suite 802, Toronto, Ontario M3C 1T5 CanadaWith over 35 years of quality service, McDougall Scientific is one of the most experienced Clinical Research Organizations around. McDougall's core services in statistics and data management, both paper-based and Electronic Data Capture (EDC), have established well-defined business processes within the company. All processes are supported by a robust Quality Master Plan, Standard Operating Procedures (SOPs), and a validated computing infrastructure. McDougall's strict adherence to its best practices over 25+ years has transferred to an expanding suite of services that now includes hosted document management services.

789 Don Mills Road, Suite 802 Toronto, Ontario , M3C 1T5 CanadaWith over 35 years of quality service, McDougall Scientific is one of the most experienced Clinical Research Organizations around. McDougall's core services in statistics and data management, both paper-based and Electronic Data Capture (EDC), have established well-defined business processes within the company. All processes are supported by a robust Quality Master Plan, Standard Operating Procedures (SOPs), and a validated computing infrastructure. McDougall's strict adherence to its best practices over 25+ years has transferred to an expanding suite of services that now includes hosted document management services.

500-180 King St. S. Canada Waterloo, ON, N2J 1P8 CanadaMetricwire helps organizations generate proprietary real-world data on individual behaviors and symptoms to identify unmet needs, fuel treatment innovation and drive value-based decisions. Top-ten pharmaceutical companies, CROs and leading academic centers of excellence across the globe use the Metricwire Software Platform to deploy real-world evidence programs and gather real-time intelligence. Our technology empowers domain experts to better understand human behaviour and create positive change in the lives of others where it matters most.

283 Duke Street West Kitchener, ON, N2H 3X7 CanadaMetricwire helps organizations generate proprietary real-world data on individual behaviors and symptoms to identify unmet needs, fuel treatment innovation and drive value-based decisions. Top-ten pharmaceutical companies, CROs and leading academic centers of excellence across the globe use the Metricwire Software Platform to deploy real-world evidence programs and gather real-time intelligence. Our technology empowers domain experts to better understand human behaviour and create positive change in the lives of others where it matters most.

100 Allstate Parkway Markham, ON, L3R 6H3 CanadaOPKO Health, Inc. is a multi-national pharmaceutical and diagnostics company that aims to establish industry-leading positions in large and rapidly growing medical markets by leveraging our discovery, development, and commercialization expertise and our novel and proprietary technologies.

120 Research Lane, Suite 203 University of Guelph Research Park Guelph, ON N1G 0B4 CanadaNutrasource Diagnostics Inc. (NDI) is a contract research organization and regulatory consulting firm specializing in regulatory consulting, clinical trials and product analytics.

Guelph, ON CanadaNutrasource Diagnostics Inc. (NDI) is a contract research organization and regulatory consulting firm specializing in regulatory consulting, clinical trials and product analytics.

661 University Avenue Suite 1300 Toronto, ON, M5G 1M1 Canada

661 University Avenue, Suite 1300 Canada Toronto, ON, M5G 1M1 Canada

5 York Street, Unit # 3 London, Ontario, N6A 1A1 CanadaNeoVentures provides research services related to the discovery and application of aptamers for diagnostic and therapeutic uses.

3430 Schmon Parkway Thorold, Ontario L2V 4Y6 CanadaNorgen Biotek provides researchers with innovative kits for Molecular Diagnostics (MDx), Sample Collection/Preservation [from Urine, Stool, Plasma/Serum/Blood, Saliva] and microRNA/RNA/DNA/Protein Purification/Clean-Up (spin-column/96-well). Our kits feature exceptional quality, ease-of-use and sensitivity. Norgen Biotek provides researchers with the tools to address any sample preservation and preparation challenge.

Thorold, ON CanadaNorgen Biotek provides researchers with innovative kits for Molecular Diagnostics (MDx), Sample Collection/Preservation [from Urine, Stool, Plasma/Serum/Blood, Saliva] and microRNA/RNA/DNA/Protein Purification/Clean-Up (spin-column/96-well). Our kits feature exceptional quality, ease-of-use and sensitivity. Norgen Biotek provides researchers with the tools to address any sample preservation and preparation challenge.

2181 Yonge Street, Suite 801 Toronto, Ontario M4S 3H7 CanadaNeuroImage offers brain imaging, molecular imaging, biomarker development, animal models of disease, and image analysis services.

Toronto, ON CanadaNeuroImage offers brain imaging, molecular imaging, biomarker development, animal models of disease, and image analysis services.

70 Little Creek Road Mississauga, ON, L5R 3E3 CanadaNormin Health was founded by Dr. Wendong Chen in 2012. Since then, Normin Health started the first observational study using hospital data to assess treatment outcomes and hospital costs associated with first-line and second-line chemotherapies in patients with non-squamous non-small cell lung cancer. With the huge success of this very first project, Normin Health has built up a highly specialized team to conduct real-world studies and develop health economic models to meet the evidence needs of developing market access strategies, supporting reimbursement submissions, and supporting commercial promotions. Normin Health has provided services to many international pharmaceutical and medical devices companies. These companies include Eli Lilly, Xian Janssen, BMS, Novartis Oncology, Gilead, Celgene, J &J, and BD. Normin Health has been highly recognized by these clients for professionalism, innovation, and quality. Normin Health is also actively developing new business to better meet market access needs. These new businesses include the development of mobile phone APP communication tool for better communications of the clinical and economic values of medical products and the development of patient follow-up mobile phone APP to fill the current real-world data gaps.

2000 Ellesmere Road Unit 16 Scarborough, Ontario, M1H2W4 Canada

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaWe are a core facility of the University of Ottawa and the Ottawa Hospital Research Institute. We provide advice on bioinformatics research design, conduct bioinformatics analysis, provide data warehousing services, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters, methodological text, etc.) Our areas of greatest expertise are: High-throughput sequencing Microarrays Genomic sequence/motif analysis Integration of multiple data sources Network analysis We have experience with many other types of bioinformatics, and/or can refer you to other local experts, depending on your needs. We can also help to arrange for the analysis of your biological samples with local core facilities such as StemCore, the Proteomics Resource Center, or the OHRI Mass Spectrometry Core Facility.

Toronto, ON CanadaOntario Cancer Biomarker Network (OCBN) focuses on discovery and development on novel biomarkers for human diseases in addition to offering mass spectrometry, immunoassays, and other assay services to support proteomics, genomics, clinical oncology, and drug development.

Ontario Institute for Cancer Research MaRS Centre 661 University Avenue, Suite 510 Toronto, Ontario, Canada M5G 0A3The Ontario Tumour Bank (OTB) provides a viable solution for cancer researchers who often face challenges in obtaining the quality and number of biospecimens required for their studies. In doing so, OTB accelerates cancer research for the development of better patient diagnostics and therapies. Vision Scientific and technological advances in genomics, proteomics, and bioinformatics are providing new insight into the cause and treatment of cancer. The analysis of human tumours offers academic and industry researchers a window into the molecular and genetic world of cancer. Through the analysis of tumours, researchers have learned about the molecular makeup of tumours, discovered biomarkers that are characteristic of tumours and identified genes responsible for specific cancers. This knowledge creates exciting possibilities for the creation of new diagnostic and prognostic tools and for the identification of targets for new drug therapies. In order for the potential of the genomics revolution to be realized, research scientists and clinicians must analyze the molecular makeup of large numbers of human tumour tissues. Although researchers can use models of the disease such as cell lines and animal tumours, at some point it becomes essential to study human tissues to understand how a disease like cancer develops in humans. Thus, researchers require access to collections of well-preserved and well-characterized tumour tissue accompanied by high-quality clinical data. Biospecimens are the key to the development and testing of next-generation diagnostics and treatments. OTB makes this type of research possible by providing the materials needed to drive high-impact studies.

Critical Care Wing, 3rd floor, room W3132 501 Smyth Road Ottawa, Ontario , K1H 8L6 CanadaThe Ottawa Hospital Research Institute’s Clinical Research Lab, located in CCW3132, is a central processing site for biological samples obtained from subjects enrolled in clinical research studies. This central processing site ensures the highest degree of consistency and reliability. The dedicated research technicians ensure that all equipment is maintained and all necessary documentation related to equipment and samples is readily available for your study. Services available includes phlebotomy, DNA/RNA/Protein/PBMC extraction, centrifugation, separation, application of a variety of commercial kits, storage (+4°C, -20°C, -80°C or -196°), shipping and much more. Test results are limited to research use; testing to guide clinical decisions must be performed through a Certified Medical Lab.

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaPluripotent stem cells are capable of differentiating into all the cells of the embryo proper and adult organism. Induced pluripotent stem cells (iPSCs) are created by reprogramming mature adult cells (such as skin cells). They offer a unique opportunity to dissect early human development, generate models of disease, and develop cellular or drug therapeutics that target a disease or target specific patients with a disease (i.e., personalized medicine). Thus, iPSCs are important tools in Regenerative/ Translational/ Personalized Medicine.

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaNondestructive visualization of virtual slices through objects The Ottawa Hospital Research Institute’s Micro CT Core Facility uses the Bruker Skyscan 1272 to produce extremely high resolution X-ray images. The system can nondestructively visualize up to 209 Megapixel virtual slices through objects. More than 2600 slices can be reconstructed after a single scan using new16Mp and 11Mp X-ray detectors in up to three offset positions. Due to phase-contrast enhancement, object details as small as 0.35um can be detected. In order to use the Facility you will need to follow these three below: Book Training time by contacting Shumei Zhong. Provide a cost center from The Ottawa Hospital or the University of Ottawa for ongoing charges. Use our online calendar to book your acquisition and analysis time ( details and access information will be provided at the time of training).

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaThe Ottawa Virus Manufacturing Facility (OVMF), supported by the Mulcahy Family is a Contract Manufacturing Organization located in the Ottawa Hospital Research Institute. The OVMF specializes in the production of Biosafety Level 2 (BSL-2) viruses for human clinical trials. Together, our highly qualified team has over 50 years of collective experience in Process Development and GMP manufacturing. We have successfully undergone GMP audits to FDA and European standards and have manufactured several oncolytic rhabdoviruses and poxviruses for clinical trials currently ongoing or completed in Canada, the United States and Europe. Our facility GMP facility. The OVMF has a validated Grade B GMP-compliant manufacturing facility specifically designed to manufacture BSL-2 pathogens. The facility has both gowning and de-gowning airlocks for proper personnel flow and validated cleaning procedures to maintain compliance with ISO 5 standards. The 37 m2 GMP facility houses a RollerCell 40 (RC40) incubator permitting the simultaneous production from 40 extended roller bottles with a combined cell growth surface area of 170,000 cm2. Process development and assay development suites. To facilitate the continuous improvement of our manufacturing process, we have a dedicated Process Development (PD) suite that contains all equipment necessary to undertake full-scale or scaled-down engineering runs. Complimentary to our GMP manufacturing core, our facility also houses a dedicated and access controlled QC/GLP testing lab. Here, we perform biochemical, potency, and identity assays that are qualified for release and characterization testing of process development samples, clinical drug products, and clinical samples. All assay development, SOP development, execution, and validation are in accordance with ICH Q2 guidelines as appropriate for early phase clinical trials, ensuring quality results for analytical procedures. Execution of all validated assays involves controlled, reference standard banks used in parallel with assay samples. All equipment is qualified for use (IQ/OQ or PQ) and calibrated. All critical equipment, including fridges, freezers, and incubators are monitored 24/7. Meeting client needs. We place a high value on the management of our academic and industry client projects, and the relationship with our clients. The OVMF has a team of dedicated project managers, and provides project management services to all of our clients as part of our offering. Project managers are responsible for ensuring all client project milestones are met, and lines of communication are clear, and streamlined. Competitive advantage: Over 50 years of collective experience manufacturing BSL-2 Poxviruses and Rhabdoviruses viruses for human clinical trials. In-house suite and staff dedicated to assay and process development. Manufacturing processes and facilities compliant with requirements of aseptic production. Onsite development and execution of validated SOPs for clinical sample processing.

501 Smyth Road Ottawa, Ontario, K1H 8L6 CanadaGenvira Biosciences at the Ottawa Hospital Research Institute specializes in designing, constructing and characterizing customized DNA and RNA viruses for gene therapy, vaccination and cancer immunotherapy. We have extensive experience in engineering both pre-clinical and clinical grade products, leading up to IND applications and clinical trials. Our mission is to provide high quality viral vectors in a timely and cost-effective manner for the scientific community. A unique advantage for Genvira’s service is that vectors engineered can be transferred seamlessly to the Ottawa Hospital Research Institute’s viral manufacturing facility for GMP-quality production, providing our clients an end-to-end solution to quickly bring novel biologics to clinics.

Room W5256 Critical Care Wing (Mailbox 511) 501 Smyth Road Ottawa, Ontario, K1H 8L6 CanadaIdentification of proteins from polyacrylamide gels, protein solutions, dried proteins, or protein digests is provided as a core service.

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaThe Cell Therapy Manufacturing Facility at the Ottawa Hospital Research Institute is designed to manufacture state-of-the-art stem and progenitor cell-based therapies for the treatment of acutely or chronically ill patients at The Ottawa Hospital. The facility is a founding member of CellCAN, the Canadian-wide network of cell manufacturing facilities. Through CellCAN, facility members actively participate in the design and execution of multi-center cell-therapy trials as well as the dissemination and implementation of Canadian regulatory guidelines. The facility is currently the primary manufacturing site for three Health Canada authorized clinical trials: Enhanced Angiogenic Cell Therapy – Acute Myocardial Infarction (ENACT-AMI) trial is a phase IIb, double-blind, randomized placebo-controlled trial of genetically transfected autologous endothelial progenitor cells in patients who have experienced a myocardial infarction. Cellular Immunotherapy for Septic Shock (CISS) is a phase I dose escalation safety trial of allogeneic mesenchymal stem cell (MSC) obtained from healthy bone marrow donors for the treatment of septic shock Mesenchymal Stem Cell Therapy for Canadian Multiple Sclerosis Patients (MESCAMS) is a phase I/II "proof-of-principle" study to examine the feasibility, safety and potential benefit of autologous MSC therapy for inflammatory forms of multiple sclerosis (MS). This is a randomized, double-blind, sham-controlled crossover trial using autologous MSCs to treat MS. To facilitate the clinical trials, two suites, each with two processing rooms, have been designed and built for cGMP processing which incorporates uniquely designed isolator technology to speed work-flow, limit costs, and increase product safety. The cell manufacturing facilities is operated under the auspices of a qualified director, with personnel trained in aseptic technique.

501 Smyth Rd, Room 4136 (mailbox 223) Ottawa, ON, K1H 8L6 CanadaThe Clinical Investigation Unit (CIU) is 12-bed clinical research facility, with an integrated Pharmacokinetics (PK) Lab, located at the General Campus of The Ottawa Hospital. The CIU has extensive experience in the design and conduct of clinical and pharmacokinetic studies in all phases of drug development from Phase I to Phase IV, including bioequivalence studies, drug-drug and drug-food interaction studies. The CIU can also provide private accommodations for short-term or prolonged overnight stays with experienced research nurses and physicians available to provide 24-hour monitoring of study participants. The CIU also operates an on-site laboratory for handling, pre-analytical processing, storage and shipment of specimens for any sample processing needs. The CIU operates according to Good Clinical Practices (GCP) and Standard Operating Procedures (SOP) which are maintained and updated on a regular basis. Furthermore, all studies are conducted according to the International Conference on Harmonization (ICH) guidelines and the principles set forth in the Declaration of Helsinki. The CIU is also well integrated with other Ottawa Hospital Research Institute support services to enable virtually any complex study design.

Room 5132, CCW 501 Smyth Road Ottawa, Ontario K1H 8L6 CanadaStemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI), and is a core facility of the University of Ottawa. StemCore Laboratories is developing a world-class infrastructure for genomics, bioinformatics, and proteomics, and is capable of facilitating large-scale scientific research and biotechnology projects.

155 College Street, Suite 424 Toronto, ON M5T, CAPOPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE The Institute for Clinical Evaluative Sciences (ICES) leads cutting-edge studies that evaluate health care delivery and outcomes. ICES researchers access a vast and secure array of Ontario’s health-related data, including population-based health surveys, anonymous patient records, as well as clinical and administrative databases. ICES goes to great lengths to protect privacy and is recognized as an international leader in maintaining the privacy and security of health information. WORLD-CLASS RESEARCH TEAMS ICES is a community of research, data and clinical experts. Many ICES scientists are internationally recognized and a number of them are practicing clinicians who understand the everyday challenges of health care delivery. They lead multidisciplinary teams that include expert statisticians and epidemiologists, as well as specialists in knowledge translation and information security, privacy and information technology. The diversity within these teams and their expertise at using ICES’ outstanding array of linked datasets is the foundation of the innovative approach to research at ICES. IMPACT ICES research results in an evidence base that is published as atlases, investigative reports and peer-reviewed papers, and is used to guide decision-making and inform changes in health care policy and delivery. Many ICES reports are undertaken to answer specific questions (known as Applied Health Research Questions) posed by health system stakeholders and policy-makers. ICES research and reports influence the design, implementation and evaluation of health policy and the delivery of health care. ICES studies and reports are highly regarded in Canada and abroad. INDEPENDENCE ICES is an independent not-for-profit corporation, and takes pride in its international reputation as a trusted, impartial and credible source of high quality health and health services research and evidence. ICES receives core funding from the Ontario Ministry of Health and Long-Term Care. ICES faculty and staff have highly successful track records competing for peer-reviewed grants from federal agencies, such as the Canadian Institutes of Health Research, and from provincial as well as international funding bodies.

G1 06, 2075 Bayview Avenue Toronto, Ontario , M4N 3M5 CanadaPOPULATION-BASED HEALTH RESEARCH THAT MAKES A DIFFERENCE The Institute for Clinical Evaluative Sciences (ICES) leads cutting-edge studies that evaluate health care delivery and outcomes. ICES researchers access a vast and secure array of Ontario’s health-related data, including population-based health surveys, anonymous patient records, as well as clinical and administrative databases. ICES goes to great lengths to protect privacy and is recognized as an international leader in maintaining the privacy and security of health information. WORLD-CLASS RESEARCH TEAMS ICES is a community of research, data and clinical experts. Many ICES scientists are internationally recognized and a number of them are practicing clinicians who understand the everyday challenges of health care delivery. They lead multidisciplinary teams that include expert statisticians and epidemiologists, as well as specialists in knowledge translation and information security, privacy and information technology. The diversity within these teams and their expertise at using ICES’ outstanding array of linked datasets is the foundation of the innovative approach to research at ICES. IMPACT ICES research results in an evidence base that is published as atlases, investigative reports and peer-reviewed papers, and is used to guide decision-making and inform changes in health care policy and delivery. Many ICES reports are undertaken to answer specific questions (known as Applied Health Research Questions) posed by health system stakeholders and policy-makers. ICES research and reports influence the design, implementation and evaluation of health policy and the delivery of health care. ICES studies and reports are highly regarded in Canada and abroad. INDEPENDENCE ICES is an independent not-for-profit corporation, and takes pride in its international reputation as a trusted, impartial and credible source of high quality health and health services research and evidence. ICES receives core funding from the Ontario Ministry of Health and Long-Term Care. ICES faculty and staff have highly successful track records competing for peer-reviewed grants from federal agencies, such as the Canadian Institutes of Health Research, and from provincial as well as international funding bodies.

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaThe Ottawa Hospital Research Institute has grown rapidly to become one of the largest and most important hospital-based research institutions in Canada and with this growth comes the development of our new Biorepository . The facility is located in the Loeb building at the Civic Campus, of The Ottawa Hospital (map) and officially opened in January 2012 with the transfer of 86,000 samples from the pilot phase of the Ontario Health Study. Along with the Ontario Institute for Cancer Research (OICR), the Ontario Agency for Health Protection and Promotion (OAHPP), and the Lunenfeld-Tanenbaum Research Institute (LTRI), the Ottawa Hospital Research Institute Biorepository is currently facilitating the Ontario Health Study (OHS), a major ongoing research study that is investigating risk factors associated with disease, by processing, accessioning and storing all of its biospecimens. One of the major goals of the Biorepository is to make a state-of-the-art facility available to researchers at The Ottawa Hospital and to help promote the safe handling, receipt, storage, inventory control, packaging and distribution for all sample types, The Ottawa Hospital Research Institute Biorepository is an extremely valuable resource for researchers and has the capability to track and store hundreds of thousands of biological samples in vapour-phase liquid nitrogen. Facility The Ottawa Hospital Research Institute Biorepository is a large-scale operation with a 1,200 square foot facility located in the basement of the Loeb building of The Ottawa Hospital’s Civic Campus. The facility is currently outfitted with six top-of-the-line cryogenic freezers, each with a 90,000 sample capacity. These high-efficiency vapour storage freezers are monitored to ensure temperature and liquid nitrogen levels are maintained within specified parameters. The Biorepository also utilizes a Laboratory Information Management System (LIMS), BioBank, which enables staff to archive, trace, and manage sample and laboratory information. This ensures complete traceability on samples and associated information.

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaInvestigator-driven clinical research is a key element in modern health care systems to improve the prevention, diagnosis and treatment of disease, bringing tremendous benefits to patients and society. OMC exists to promote and facilitate methodological excellence in clinical research at The Ottawa Hospital, one of the largest hospitals in Canada. Created in 2006, OMC is an initiative of the Ottawa Hospital Research Institute centred within the Clinical Epidemiology Program. Ottawa Methods Center scientists are internationally recognized for their contributions to clinical trial methodology, knowledge synthesis, data management and statistics. The availability of the OMC to provide expertise and support to health professionals and researchers at all stages of a research project has been instrumental in the recognition of The Ottawa Hospital as one of the leading centers for clinical research in Canada. The OMC supports over 50 positions (scientists, and research support staff; both funded and affiliated) and operates primarily on a fee for service basis.

501 Smyth Box 511 Ottawa , ON , K1H 8L6 CanadaFlow cytometry is the science of examining physical and chemical properties of live cells, beads or other biological particles as they pass in a fluid stream through a measuring apparatus. This apparatus, known as a flow cytometer, uses laser excitation and signal detection to measure parameters such as size, shape, DNA content, surface receptors, enzyme activity, membrane permeability and calcium flux. Some flow cytometers, called sorters, are equipped to separate and collect cells or beads of interest. High-performance flow cytometers and high-speed cell sorters have applications in cancer and HIV research, drug discovery, stem cell and gene therapy. The Ottawa Hospital Research Institute Flow Cytometry Facility, located at the General Campus of the Ottawa Hospital, was established in 1998 and now includes three flow cytometers, two of which have sorting capabilities. We offer the sorting precision required for the isolation of rare cell populations with high purity and yield, up to 20 000 events per second. As well as sorting, flow cytometers allow the simultaneous analysis of a variety of light scatter and fluorescence parameters on single cells.

OTAVA Ltd. 400 Applewood Crescent, Unit 100 Vaughan, Ontario, L4K 0C3 CANADAOTAVA offers: Synthesis of high-quality small organic compounds for HTS, chemical building blocks and intermedieates Full range of custom synthesis and hit-to-lead optimization services Rational design of inhibitors of protein kinases and other drug targets Wide selection of target-focused libraries, design on request option Molecular modeling/computational chemistry services Development of novel fluorescent probes

400 Applewood Crescent, Unit 100 Concord, ON, L4K 0C3 CanadaOTAVA offers: Synthesis of high-quality small organic compounds for HTS, chemical building blocks and intermedieates Full range of custom synthesis and hit-to-lead optimization services Rational design of inhibitors of protein kinases and other drug targets Wide selection of target-focused libraries, design on request option Molecular modeling/computational chemistry services Development of novel fluorescent probes

2 Chelsea Lane Brampton, Ontario L6T 3Y4 CanadaPHARMCO-AAPER is a manufacturer of Pure and Denatured Ethanol, High Purity Chemicals and Sterile Solvents.

Toronto, ON CanadaPathMatrix developed a software platform for modeling of normal physiology and disease pathophysiology in support of virtual screening, disease model simulation, in silico predictions, and signal transduction pathway studies.

3760 14th Avenue Suite 201 Markham, Ontario L3R 3T7 CanadaPharmEng is a full service consulting form for pharmacutical, medical device and biotechnology industries.

Markham, ON CanadaPharmEng is a full service consulting form for pharmacutical, medical device and biotechnology industries.

Mississauga, ON CanadaPharmachem Access offers CMC consulting, process analytical technology, regulatory affair, technology transfer, and process design.

160 College Street, Room 1204, Toronto, Ontario, M5S 3E1 Canada

4770 Sheppard Avenue EastPharma Medica Research offers phase I bioequivalence studies and phase II clinical trials as well as bioanalysis, custom organic molecule synthesis of drug metabolites, and biostatistics.

6100 Belgrave RoadPharma Medica Research offers phase I bioequivalence studies and phase II clinical trials as well as bioanalysis, custom organic molecule synthesis of drug metabolites, and biostatistics.

130 Colonnade Road A.L. 6501H Ottawa, Ontario, K1A 0K9 CanadaFor Our Health - as Canada’s leading public health infectious disease laboratory, the National Microbiology Laboratory (NML) is responsible for the identification, control and prevention of infectious diseases. The NML is located at the Canadian Science Centre for Human and Animal Health in Winnipeg, the first facility in the world to have high containment laboratories for human and animal health in one building. It is recognized as a leader in an elite group of centres around the world, equipped with laboratories ranging from biosafety level 2 to level 4 designed to accommodate the most basic to the most deadly infectious organisms. The NML is Canada's main infectious disease public health laboratory with responsibility for reference microbiology and quality assurance, laboratory surveillance for infectious diseases, emergency outbreak preparedness and response, training, and research and development. The information contained in this website is intended to provide reference information for public health professionals and the general public on the various programs and activities undertaken by the Public Health Agency of Canada’s National Microbiology Laboratory.

365 Madawaska Blvd. Arnprior, ON, K7S 0C9Pillar5 Pharma manufactures and packages oral solid and sterile opthalmic products.

100 Collip Circle, Suite 215 London, Ontario N6G 4X8 CanadaPolyAnalytik specializes in size exclusion, gel permeation, and gel filtration chromatography services to support analysis of macromolecules.

111 Consumers Drive Whitby, Ontario L1N 5Z5 CanadaPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

2100 Syntex Court Mississauga, Ontario L5N 7K9 CanadaPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

269 Castlehill Close London, Ontario, N6G 0K4 CanadaPrecision Proteomics is a biotechnology company commercializing a novel platform for the development of next-generation precision medicines. Precision was created to apply cutting-edge proteomics to the development and clinical utilization of therapeutics. Precision’s technology can systematically and quantitatively profile activations of key signal pathways that drive pathogenesis and the development of resistance to therapy. The company is actively building research and development partnerships with biopharmaceutical companies globally in respect of approved and emerging therapies, and will at the same time advance proprietary programs based on its discovery of novel therapeutic targets in certain cancers with high unmet need.

SDRI107A; Dental Sci, Dock#15 1151 Richmond St London, Ontario, N6A 5C1 CanadaPrecision Proteomics is a biotechnology company commercializing a novel platform for the development of next-generation precision medicines. Precision was created to apply cutting-edge proteomics to the development and clinical utilization of therapeutics. Precision’s technology can systematically and quantitatively profile activations of key signal pathways that drive pathogenesis and the development of resistance to therapy. The company is actively building research and development partnerships with biopharmaceutical companies globally in respect of approved and emerging therapies, and will at the same time advance proprietary programs based on its discovery of novel therapeutic targets in certain cancers with high unmet need.

1400 Western Road Suite G22 London, ON, N6G 2V4 CanadaPrecision Proteomics is a biotechnology company commercializing a novel platform for the development of next-generation precision medicines. Precision was created to apply cutting-edge proteomics to the development and clinical utilization of therapeutics. Precision’s technology can systematically and quantitatively profile activations of key signal pathways that drive pathogenesis and the development of resistance to therapy. The company is actively building research and development partnerships with biopharmaceutical companies globally in respect of approved and emerging therapies, and will at the same time advance proprietary programs based on its discovery of novel therapeutic targets in certain cancers with high unmet need.

999 Collip Circle London, Ontario, N6G 0J3 CanadaPrecision Proteomics is a biotechnology company commercializing a novel platform for the development of next-generation precision medicines. Precision was created to apply cutting-edge proteomics to the development and clinical utilization of therapeutics. Precision’s technology can systematically and quantitatively profile activations of key signal pathways that drive pathogenesis and the development of resistance to therapy. The company is actively building research and development partnerships with biopharmaceutical companies globally in respect of approved and emerging therapies, and will at the same time advance proprietary programs based on its discovery of novel therapeutic targets in certain cancers with high unmet need.

428-192 Spadina Ave. Toronto, ON, ON, M5T 2C2 CanadaPrivate AI helps Detect, anonymize, and replace 50+ entities of personal information on premise, in 52 languages with better accuracy than Big Tech.

428-192 Spadina Ave. Toronto, ON, ON, M5T 2C2 CanadaPrivate AI helps Detect, anonymize, and replace 50+ entities of personal information on premise, in 52 languages with better accuracy than Big Tech.

1348 Sandhill Dr. Ancaster, ON, L4G3Z9 CanadaPrecision BioLogic is a privately-held company that develops, manufactures and markets specialized products used by medical professionals and researchers around the globe to diagnose coagulation disorders. Precision BioLogic also has several active initiatives with pharmaceutical partners who seek to ensure that the diagnostic implications for their novel therapeutic agents have been well characterized.

110 Industrial Parkway North, Aurora Aurora, Ontario, L4G 3H4 CanadaPiramal Pharma Solutions is a Global Contract Research Development and Manufacturing Organization (CRDMO), offering end-to-end drug discovery, development and manufacturing services through our global network of 14 sites located in India, UK & North America (Canada & USA). With 350+ FTE’s the Ahmedabad, India based small molecule discovery services division has been in business since 2003 and our capabilities include: - Custom Synthesis of individual compounds, building blocks, scaffolds, focused libraries (40 to 100 compounds), reference standards, impurities & metabolites - DMPK & In-Vitro Biology - Route Scouting leveraging our global process chemistry expertise across US, Canada & India - Non-GMP scale up (up to 5kg) - Analytical services including method development (non-GMP), mg to gm scale separation of Chiral/ Achiral compounds We work on both FTE and Fee Based models. Through our global network in India and North America we offer small molecule intermediates, API development and GMP manufacturing. Our formulations capabilities include oral solids, liquids and Lyophilized product development and GMP manufacturing. We also offer specialized capabilities including antibody drug conjugation (ADC), High Potent API (HPAPI's) and Peptides GMP development and manufacturing .

2 county court Suite 400 Brampton, Ontario, L6W 3W8 CanadaPharmaffiliates has achieved global recognition within a very short span of time. We have established strategic international partnerships with the leading companies in healthcare to support our vision. We are USFDA accepted facility, ISO 9001:2008 & ISO 17025:2005 and ISO Guide 34 providing World Class Analytical Testing Services around the globe. Precision analytical technologies are required to assess production quality and to determine trace level impurities which may present a risk to human health or the environment. These technologies are often highly specialized analytical instruments which can only be operated by scientists who have industry application experience. We strive to work with the best in the industry. We have already set a benchmark by developing, validating and submitting over 400 methods to European and US Authorities. We empower clients ranging from emerging biotech to Top Global Pharma companies to reach confident clinical decisions that ultimately serve to improve patient lives. We are in collaboration with the best in the industry like Glenmark Pharmaceuticals, Orion, Specifar, Genepharm, Pharos , Pharmasol, Teva, DSM, Ranbaxy, Dr Reddy’s, Cipla, Zydus, Torrent, Alembic etc. to name a few. Presently we are offering a comprehensive range of analytical services using our network of state-of-the art laboratories our analytical capabilities are complemented by extensive services, e.g.: Analytical Method Development Method Validation, Method Transfer, Method Verification Stability studies Regulatory services (DMF filling, Dossier Preparation) Package Testing Product Testing Quality Assurance Quality Control USP Testing Analytical Reagents Compendial Testing Elemental Analysis Heavy Metals Analysis Technologies are calibrated to your deposit, and methods and detection limits are reviewed and validated regularly to ensure that data quality objectives are being met and maintained. Our QA/QC protocol is the backbone of the service, controlling methodology, data management and reporting, quality control and governance activities.

4673 Downey Road Guelph, Ontario N1H 6J3Quorum Technologies Inc. is a private, Canadian owned enterprise located in Guelph, Ontario. The company develops and integrates scientific instruments and is the leading provider of technologies to support Digital Pathology, Telepathology and the Life Sciences community with over 100 of these installations across the country. Quorum dedicates over 30 years of experience integrating microscope components to meet the goals of the scientific community and holds over half a dozen patents with several others in process. Through a variety of technology transfer relationships with Canadian universities, Quorum is helping to bring new innovative technologies to market for use in preclinical research, drug development and personalized medicine.

145 Konrad Crescent, Suite 11 Markham, Ontario L3R 9T9 CanadaQuality Compliance Laboratories (QCL) offers quality control testing, stability studies, method development/validation, and microbiological testing services.

100 Perth Drive, Rm. 4242 London, Ontario, Canada N6A 5K8The Molecular Pathology core facility at Robarts includes a full spectrum of state-of-the-art histopathology equipment and expertise. The facility enables investigators to study fresh, frozen or paraffin-processed tissues and analyze sections using various histological stains and molecular probes. In addition, micro-isolation of discrete cells within tissue sections can be accomplished using laser capture microscopy.

Imaging Research Laboratories, Robarts Research Institute The University of Western Ontario, 1151 Richmond St. North London, Ontario, N6A 5B7 CanadaWe are developing innovations for medical imaging, a field that has revolutionized medicine this century. During the last three decades, medical imaging has advanced beyond film-based x-rays to sophisticated computerized imaging techniques like digital subtraction angiography (DSA), computed tomography (CT) and magnetic resonance imaging (MRI). Our group consists of 13 principal investigators and 19 associated principal investigators.

100 Perth Drive London, Ontario Canada N6A 5K8Robarts Clinical Trials offers clinical research services including study design, project management, safety management, and data management.

London, ON CanadaRobarts Clinical Trials offers clinical research services including study design, project management, safety management, and data management.

Markham, ON CanadaRIMAX Research offers phase I-IV clinical research services including clinical trial management, project management, first in human studies, bioavailibility/bioequivalence studies, pharmacokinetics/pharmacodynamics, and drug interaction studies in the therapeutic areas of cardiology, dermatology, endocrinology, neurology, respiratory, and urology.

2680 Matheson Blvd. East, Suite 102 Mississauga, ON L4W 0A5 CanadaRidgewood Research is a Canadian company dedicated to providing high tech services in the areas of research and development for the pharmaceutical, food, cosmetics, and other R&D establishments.

1151 Richmond St. N., London, Ontario, CanadaThe Robarts Research Institute Neurobehavioral Core Facility (NCF) was established to provide Western University and the external research community with access to equipment, software and services for the performance of behavioral experiments in mouse models.

661 University Avenue Suite 1300 Toronto, ON, M5G 1M1 CanadaVariantFind™ is a division of Ranomics that solely focuses on applying the Ranomics' Multisite Saturation Mutagenesis technology to generating comprehensive variant libraries. We are committed to providing top quality variant libraries at competitive costs with quick turn-around time.

661 University Ave Toronto, Ontario, Canada M5G 1M1 Suite 1300 Toronto, ON, M5G 1M1 CanadaVariantFind™ is a division of Ranomics that solely focuses on applying the Ranomics' Multisite Saturation Mutagenesis technology to generating comprehensive variant libraries. We are committed to providing top quality variant libraries at competitive costs with quick turn-around time.

137 Glasgow Street Unit 450 Kitchener, ON, N2G 4X8 CanadaRapid Novor specializes in mass spectrometry-based proteomics, protein sequencing, antibody discovery, peptide mapping, HDX-MS epitope mapping, SPR binding kinetics, and characterization. Our team is dedicated to developing antibody protein sequencing and characterization technologies that supercharge worldwide research. You provide: monoclonal antibody sample (>0.1mg, >80% pure) or affinity purified polyclonal antibody sample. These requirements are not set in stone, please let us know about your project! We deliver: full sequence of heavy and light chains; Full sequence coverage by LC-MS/MS; Comprehensive report and Raw LC-MS/MS data and other notable observations. We guarantee at least 5X coverage of the CDRs, average 30X coverage for 100% of the sequence. We also offer species agnostic polyclonal antibody sequencing & discovery.

Unit 1504 88 Corporate Drive Toronto, ON, M1H 3G6 CanadaScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

555 University Avenue Toronto, Ontario Canada M5G 1X8

4174 Dundas Street West Suite 300SciAn Services offers phase I-IV clinical research services including trial management, site management, data management, consulting, and regulatory support.

Cra 100 # 5-169 Oficina 602STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

36 Meteor Drive Toronto, ON, M9W 1A4 CanadaSQI Diagnostics supports better healthcare through faster, more accurate multiplexing technology.Specifically, we help generate more comprehensive data from single tests, using an automated process that also reduces experimental variables and handling errors. Associated services significantly reduce the time and cost of assay development. We believe you already have the ingenuity to dramatically improve quality of life. Our job is to provide the tools and services that will progress those ideas to market faster.

Toronto, ON CanadaSimBioSys offers computational chemistry services including molecular docking (flexible ligand docking & fast pre-docking), pharmacophore modelling, 3D database search, de novo design and 3D visualizations techniques.

135 Queen's Plate Drive Unit 520SimBioSys offers computational chemistry services including molecular docking (flexible ligand docking & fast pre-docking), pharmacophore modelling, 3D database search, de novo design and 3D visualizations techniques.

ON CanadaStiris Research offers comprehensive study management solutions for phase I to phase IV clinical research.

4575 Blakie Road 2nd Floor London, Ontario, Canada N6L 1P8Stiris Research offers comprehensive study management solutions for phase I to phase IV clinical research.

2838 Bovaird Drive WestSunOpta provides natural products for sale as well as product formulation, custom ingredient, and quality control services.

50 Viceroy Road Unit 7 Concord, Ontario, L4K 3A7 CanadaSynthose is a premier manufacturer of carbohydrates and glycoconjugates. We specialize in the synthesis of natural glycosides, drug metabolites, orthogonally protected building blocks, and the stable labelling of sugars. We currently have a catalogue of over 900 chemicals, and we are releasing new products each week in line with the latest research of our customers. With thousands of available intermediates and over ten years in development of synthetic routes towards sugars, our scientific team can quickly deliver the compound you need for your project.

Technology Building, Suite 702BSequenom sells genetic analysis products that can be used for DNA methylation analysis, SNP genotyping, gene expression analysis, rare mutation profiling, methylation analysis and quantitative gene expression.

999 Collip Circle London, ON, N6G 0J3 CanadaA consulting and search laboratory specializing in the analysis and characterization of surfaces and material.

477 Richmond St West Unit 306 Toronto, ON, M5V 3E7 CanadaSelf Care Catalysts is a patient-centered digital therapeutics, intelligence and analytics company deriving value from patient-centered real world evidence to inform clinical care, product life cycle management and behavior change interventions. Self Cate Catalysts promotes the Health Storylines platform that enables patient - centered digital trials, patient reported outcomes generated in real world, real time, over time.

100 Sussex Drive Suite 1120B Ottawa, ON, K1A0R6 CanadaSussex Research is a leading global specialist carbohydrate synthesis including GalNAc, Glycan, Glycopeptide and Glycoconjugate synthesis. The company excels at the discovery and development of molecules that explore and exploit glycobiology or incorporate glycotechnology. Our unique carbohydrate product portfolio and synthetic capabilities enable researchers across a variety of scientific disciplines to readily explore and exploit novel molecules in order to enhance the therapeutic potential of lead molecules or advance drug development. We have enabled application of complex carbohydrate systems for drug discovery, drug delivery, drug targeting, carbohydrate-based vaccine development, immunotherapy, therapeutic enhancement, monoclonal antibody development and diagnostic/bio-analytical assay development. Sussex Research offers a portfolio of diverse carbohydrate-based products and custom synthesis, as well as non-GLP analytical and bioanalytical services.

100 Sussex Drive, Suite 1120G Ottawa Ontario K1A 0R6 CanadaSussex Research is a leading global specialist carbohydrate synthesis including GalNAc, Glycan, Glycopeptide and Glycoconjugate synthesis. The company excels at the discovery and development of molecules that explore and exploit glycobiology or incorporate glycotechnology. Our unique carbohydrate product portfolio and synthetic capabilities enable researchers across a variety of scientific disciplines to readily explore and exploit novel molecules in order to enhance the therapeutic potential of lead molecules or advance drug development. We have enabled application of complex carbohydrate systems for drug discovery, drug delivery, drug targeting, carbohydrate-based vaccine development, immunotherapy, therapeutic enhancement, monoclonal antibody development and diagnostic/bio-analytical assay development. Sussex Research offers a portfolio of diverse carbohydrate-based products and custom synthesis, as well as non-GLP analytical and bioanalytical services.

145 Konrad Crescent Markham, ON, L3R 9T9 CanadaSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

6490 Vipond Drive Mississauga ,0N Canada L5T 1W8SGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

1380 Rodick Road Markham Toronto, ONTARIO, L3R 4G5 CanadaWe’re here to be the solutions partner to biomedical researchers. Providing reliable and repeatable insights that transform scientific discoveries into better outcomes. Improving operating systems through more focused, methodical and consistent processes and an emphasis on quality. Delivering important value to our customers and their research.

110 Cumberland St., Suite 406 Toronto, ON, M5R 3V5 CanadaConvenient, reliable and cost effective research and development services the life scientists trust and rely on.

3850 Finch Ave E #306 Scarborough, ON, M1T 3T6 CanadaConvenient, reliable and cost effective research and development services the life scientists trust and rely on.

48 George Street Aurora Ontario L4G 2S2 CanadaTorealis offers management of various stages of clinical research and pharmaceutical development.

Aurora, ON CanadaTorealis offers management of various stages of clinical research and pharmaceutical development.

2-70 Villarboit CrescentTLC PharmaChem specializes in custom synthesis of complex organic chemicals for biomedical and pharmaceutical research.

Brockville, CanadaTrillium Health Care Products manufactures high quality OTC and Prescription products and services for the pharmaceutical industry

Brockville, ON CanadaTrillium Health Care Products manufactures high quality OTC and Prescription products and services for the pharmaceutical industry

330 Nantucket Boulevard Toronto, ON M1P 2P4 CanadaTekran® was founded in Toronto, Canada in 1989 to develop custom analytical instrumentation for environmental analysis. Our first analyzer, the Tekran® 2537, was introduced in 1993 and is now widely accepted as the gold standard for automated ambient air analysis of mercury. Tekran® continues to expand and improve our product lines, which are focused exclusively on instruments and systems for mercury measurement. We now offer systems for ambient air mercury speciation monitoring, automated analysis of total mercury and methyl mercury in environmental samples, total mercury in natural gas, and mercury continuous emission monitoring of coal-fired power plants and other industrial emission sources. We also offer a wide range of secondary equipment to support our main product lines.

330 Nantucket Boulevard Toronto, ON, M1P 2P4 CanadaTekran® was founded in Toronto, Canada in 1989 to develop custom analytical instrumentation for environmental analysis. Our first analyzer, the Tekran® 2537, was introduced in 1993 and is now widely accepted as the gold standard for automated ambient air analysis of mercury. Tekran® continues to expand and improve our product lines, which are focused exclusively on instruments and systems for mercury measurement. We now offer systems for ambient air mercury speciation monitoring, automated analysis of total mercury and methyl mercury in environmental samples, total mercury in natural gas, and mercury continuous emission monitoring of coal-fired power plants and other industrial emission sources. We also offer a wide range of secondary equipment to support our main product lines.

Mississauga,The Clinical Trial Company offers clinical research services including project management, regulatory affairs, clinical and preclinical studies, and safety/efficacy studies with expertise in gene therapy, cardiology, hematology, dermatology, urology, oncology, endocrinology, immunology, respiratory, CNS, and ophthalmology.

686 Bay Street, Room 139800 Toronto, Ontario M5G 0A4, CanadaTCAG at The Hospital for Sick Children Biobanking and Databasing Facility provides DNA extraction from lymphoblasts, fibroblasts and other cell types, archiving of white cell pellets, preparation and immortalization of cell lines, and comprehensive databasing and tracking of samples and/or cell lines within the facility.

Toronto, ON CanadaThe Centre for Applied Genomics at The Hospital for Sick Children offers microarray, cytogenomic, biobanking, and sequencing services.

60 St. Clair Avenue East, Suite 702Trial Management Group offers phase II-IV clinical research services for many therapeutic areas.

399 Bathurst Street Toronto, ON , M5T 2S8 CanadaToronto Western Hospital is located in the vibrant heart of the downtown communities of South Annex, College, Queen and King Street West. It is a 272-bed academic health science centre dedicated to delivering exceptional patient care, providing a breadth of services from emergency care to sophisticated brain surgery. As a world leader in neuroscience, TWH is constantly pushing the boundaries of research, offering pioneering treatments and using state-of-the-art technology. The hospital also has a strong community focus, providing innovative programs for and information to children, seniors, diabetes patients and many multicultural groups. With expertise in musculoskeletal health and arthritis, the hospital's programs also include orthopaedics, rheumatology and the hand program as well as a busy Emergency Department that sees more than 60,000 patients yearly.

96 Skyway Avenue Toronto, ON, M9W 4Y9 CanadaTrillium Therapeutics Inc. (TTI) is a privately-owned biopharmaceutical company with two main areas of focus: cytoprotection and immune regulation. The Company's cytoprotection programs are based upon a recombinant form of heparin-binding epidermal growth factor-like growth factor (HB-EGF).

1280 Main Street West Hamilton, ON, L8S 4L8 CanadaTo provide a variety of spectroscopic techniques for sample analyses, and is made available to the Department, the University, and other academic, government,or industrial laboratories.

200 Elizabeth Street Toronto, ON , M5G 2C4 CanadaToronto General Hospital (TGH) is one of Toronto’s oldest hospitals, dating back to 1819 when the Loyal and Patriotic Society of Upper Canada organized a trust fund to support the construction and maintenance of a hospital in the provincial capital, the Town of York. Construction began in 1820 and the General Hospital of the Town of York was opened for patients in June 1829 at Simcoe and King Streets. As Toronto General, it expanded to Gerrard and Sumach in 1856 and then to College Street in 1913. The College Street location has since become the MaRS building, while Toronto General has spread out south along University Avenue. Among its world firsts, TGH performed the world’s first successful single lung transplant in 1983, followed by the first double-lung transplant in 1986. In 1950, the first external heart pacemaker was used in an open-heart resuscitation. And in 1922, insulin was developed and saw its first clinical use in the treatment of diabetes on a young patient at TGH.​​​

2655 North Sheridan Way Suite 120 Mississauga, ON L5K 2P8 CanadaTheorem Clinical Research offers full service clinical research solutions including DM, biostatistics, programming including CDISC, PM, clinical operations, and regulatory affairs.

2585 Meadowpine BoulevardTherapure Biopharma provides biomanufacturing solutions and drug development.

686 Bay Street, Room 139800 Toronto, Ontario M5G 0A4, CanadaTCAG at The Hospital for Sick Children Microarray Analysis and Gene Expression Facility offers a comprehensive set of microarray based services to researchers in the academic, commercial and pharmaceutical communities.

Toronto, ON CanadaTCAG at The Hospital for Sick Children Microarray Analysis and Gene Expression Facility offers a comprehensive set of microarray based services to researchers in the academic, commercial and pharmaceutical communities.

25 Orde St. Toronto, Ontario, M5T 3H7 CanadaThe strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide: - Custom services for the generation of genetically engineered mouse models - Mouse holding and technical services for preclinical in vivo research projects - Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation - Biorepository services to archive, acquire, and distribute mouse models

25 Orde StreetThe strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide: - Custom services for the generation of genetically engineered mouse models - Mouse holding and technical services for preclinical in vivo research projects - Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation - Biorepository services to archive, acquire, and distribute mouse models

25 Orde Street Toronto, ON, M5T 3H7 CanadaThe strength of TCP is our collective expertise and unique ability to design, generate, hold, analyze, archive, and distribute a critical mass of mouse models under one roof. We provide: - Custom services for the generation of genetically engineered mouse models - Mouse holding and technical services for preclinical in vivo research projects - Comprehensive or disease-specific phenotyping, host response analysis to in vivo immunological challenges and pathology services for research, and drug discovery and evaluation - Biorepository services to archive, acquire, and distribute mouse models

D-Mark Biosciences 35 Grand Marshall Drive Toronto, ON M1B 5W9 CanadaTransomic offers next generation genomic tools and genomic services to life science researchers. We have whole genome arrayed CRISPR, shRNA, and cDNA libraries all in house. All clones are sequence verified. Custom offerings: • CRISPR and shRNA screening pools delivered as ready to us high titer lentiviral particles. Screening pools are created from our in-house libraries or we can custom synthesize oligo pools and clone into large selections of lentiviral vectors. All screening pools go through NGS to ensure equal representation. • Custom screening services including NGS and analysis • Gene synthesis and cloning into a large selection of lentiviral vectors • Stable cell line production • Lentiviral packaging services • 96-well DNA prep services

515 Legget Drive Suite 204 Kanata, ONTARIO, K2K 3G4 CanadaWith over 25 years of experience in medical research and writing, Thera-Business is positioned as a preferred partner across the pharmaceutical, medical device, and government sectors. The company’s services include: FDA submissions (i.e., 510Ks; INDs, PMAs, NDSs, SEs, CSRs, PSURs, and IBs); systematic reviews/ meta-analyses; RWE/HEOR/clinical study design and execution; survey design, post-market surveillance; study protocols (i.e., synopses and amendments); and EU MDR/IVDR implementation. Thera-Business is distinguished by its world-class team of experts with unparalleled clinical, technical, and writing skills. Ranging from the simplest to highly complex, we have an extensive track record of successfully completing projects accurately, efficiently, on-time, and according to predefined budgets. Our broad range of services build from a foundational collaboration with each client that responds to their specific needs and ensures the successful execution of projects. Our demonstrated history of excellence empowers clients to adeptly and successfully navigate the intricate challenges of the regulatory landscape.

P.O. Box 248 Fergus Ontario, N1M 2W8 CanadaTranspharmation provides translational pre-clinical and clinical pharmacology services to the pharmaceutical and biotechnology industry, with the aim of better understanding potential new medicines as they transition into the clinic.

200 University Avenue West Waterloo, ON, N2L 3G5 CanadaUniversity of Waterloo Central Animal Facility specializes in animal studies with capabilities in surgery, necropsy, antibody production, and behavioral research.

D'Iorio Hall Room 124 Ottawa, ON, K1N 6N5 CanadaLocated in D’Iorio Hall, the JLH Facility provides mass spectrometry services to the Chemistry Department, users from the University of Ottawa and beyond.

136 Jean-Jacques Lussier, Room 2041 Ottawa, Ontario, K1N 6N5 CanadaThe Core Facility provides flow cytometry and cell sorting services to the entire University of Ottawa research community as well as to others in the Ottawa area. A skilled staff provides help with sorting, data acquisition, data analysis, and consultation for experiment design. Training is available to enable investigators and their staff to run the analytical cytometers themselves at reduced cost. A major part of our mission is to teach this technology to investigators, students, and staff. Please do not hesitate to contact us if you have any questions about flow cytometry, you want to know how to use it in your research, how to design experiments, prepare samples, or how to analyze your data.

136 Jean-Jacques-Lussier Private, Ottawa, ON K1N 9A8, CAThe Core Facility provides flow cytometry and cell sorting services to the entire University of Ottawa research community as well as to others in the Ottawa area. A skilled staff provides help with sorting, data acquisition, data analysis, and consultation for experiment design. Training is available to enable investigators and their staff to run the analytical cytometers themselves at reduced cost. A major part of our mission is to teach this technology to investigators, students, and staff. Please do not hesitate to contact us if you have any questions about flow cytometry, you want to know how to use it in your research, how to design experiments, prepare samples, or how to analyze your data.

25 Templeton Street Advanced Research Complex Ottawa, ON, K1N 6N5 CanadaThe internationally known G.G. Hatch Stable Isotope Laboratory operates on a cost-recovery basis, serving the H, C, N, O and S stable isotope analysis needs of the uOttawa community as a whole, as well as those of other University, Government and Private Agencies around the world. We have now successfully moved into the brand new Advanced Research Complex, into a brand new custom space. We are happy to announce that we are back up and running. Please take note of our new address: 25 Templeton Street, Room 426. Contact us to arrange a visit and/or a tour of our new facility.

25 Templeton Street, Ottawa, ON K1N, CAThe internationally known G.G. Hatch Stable Isotope Laboratory operates on a cost-recovery basis, serving the H, C, N, O and S stable isotope analysis needs of the uOttawa community as a whole, as well as those of other University, Government and Private Agencies around the world. We have now successfully moved into the brand new Advanced Research Complex, into a brand new custom space. We are happy to announce that we are back up and running. Please take note of our new address: 25 Templeton Street, Room 426. Contact us to arrange a visit and/or a tour of our new facility.

2075 Bayview Avenue, M7 122 Toronto, ON, M4N 3M5 CanadaThe capacity to create novel devices is a cornerstone of medical innovation. In Sunnybrook Research Institute's device development laboratory—Canada's first of this scope based in a hospital—scientists and engineers are designing and producing complex medical devices under highly controlled conditions. The overarching aim is to design more effective and safer ways to detect disease, deliver therapy and guide interventions. Devices are then tested for proof of principle and, if successful, clinically, in collaboration with other researchers and clinicians. Ultimately, our aim is to commercialize the devices we invent, so we can move them into the medical marketplace to benefit patients. Main goals are as follows: To accelerate development of clinically relevant medical devices for large-scale or orphan applications To design, fabricate, test and validate candidate devices efficiently To create a centre of expertise for teaching skills related to device development, preclinical testing and validation To provide facilities and expertise that enable commercialization of new devices

20 Marie Curie room 319 Ottawa, Ontario, K1N 6N5 CanadaThe Core Molecular Biology and Genomics Laboratory provides services in genomics and molecular biology, serves as a research training site and provides access to advanced molecular biology/genomics equipment. Services DNA Sequencing Droplet Digital PCR

20 Marie-Curie Private, Ottawa, ON K1N 9B4, CAThe Core Molecular Biology and Genomics Laboratory provides services in genomics and molecular biology, serves as a research training site and provides access to advanced molecular biology/genomics equipment. Services DNA Sequencing Droplet Digital PCR

Toronto, ON CanadaUniversity of Toronto Service Crystallography Laboratory offers X-ray crystallography services.

Dept. of Chemistry, University of TorontoUniversity of Toronto Service Crystallography Laboratory offers X-ray crystallography services.

2075 Bayview Avenue, M7 109 Toronto, ON, M4N 3M5 CanadaThe advanced machine shop is part of the device development lab within the Centre for Research in Image-Guided Therapeutics at Sunnybrook Research Institute. It is a state-of-the-art facility equipped for the design, fabrication and testing of medical devices. It specializes in the manufacture of magnetic resonance imaging-compatible devices, prototypes, custom-made parts and catheter-based devices, and in 3-D computer-assisted design. The technicians within the facility are capable of working from drawings, hand sketches or ideas in one's head, and can help transform a concept into a working prototype. Materials used in the facility include aluminum, stainless steel, plastics, brass, wood and exotic materials. The facility is equipped with a computer numerical controlled lathe and mill, five-axis waterjet cutter, rapid prototypers (stereolithography and fused deposition modeling technology in a variety of materials), manual lathes, manual mills, hydraulic shear, bender, table saw, router and bead blaster. The machines and services of technicians are available to users within Sunnybrook Research Institute, the hospital, external academic institutions and industrial clients at competitive rates. In addition to fabricating parts, the facility performs testing and characterization of medical imaging systems in partnership with Sunnybrook Research Institute scientists.

University of Ottawa Ottawa, Ontario, K1N 6N5 CanadaWe are a core facility of the University of Ottawa and the Ottawa Hospital Research Institute. We provide advice on bioinformatics research design, conduct bioinformatics analysis, provide data warehousing services, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters, methodological text, etc.) Our areas of greatest expertise are: > High-throughput sequencing, > Microarrays, > Genomic sequence/motif analysis > Integration of multiple data sources > Network analysis We have experience with many other types of bioinformatics, and/or can refer you to other local experts, depending on your needs. We can also help to arrange for the analysis of your biological samples with local core facilities such as StemCore, the Proteomics Resource Center, or the OHRI Mass Spectrometry Core Facility.

Toronto, ON CanadaUniv. of Toronto Department of Anesthesia focuses on research.

London, ON CanadaUniversity of Western Ontario focuses on research and offers contract services through its facilities and partnered institutions.

2075 Bayview Avenue, A3 38 Toronto, ON, M4N 3M5 CanadaThe antibody core facility purifies by affinity chromatography antibodies specific for cell differentiation markers, signalling and tagging molecules of various species. We conjugate these antibodies to various fluorochromes (fluorescein, allophycocyanin, phycoerythrin, and up to 20 different Alexa Fluor dyes), to biotin, and to microbeads for cell surface multicolour immunofluorescence, immunohistochemistry, functional assays and biochemical analyses. Following purification and conjugation of an antibody, the optimal titer for various applications is determined. Aside from antibodies, the facility also produces other reagents needed for various molecular biology techniques. Please contact Philippe Poussier for more information.

Room 4510 451 Smyth Road Canada Ottawa, ON, K1N 8M5 CanadaThis facility contains a Singer ROTOR HAD, a compact benchtop robot for easy, ultra-fast manipulation of high density arrays of yeast. It also contains imaging equipment and a spectrometer for automated growth curve analysis, to allow for functional and chemical genomic yeast screening of mutant collections.

Unit 10 - 1085 Bellamy Road NorthUnited Bioscience Canada Corporation (UBCC) is a high quality provider of Hyaluronic Acid using an exclusive fermentation technology as opposed to traditional methods of production.

Faculty of Medicine Ottawa, ON, K1N 6N5 CanadaThe Containment Level 3 (CL3) Laboratory Core Facility is a major infrastructure initiative of the University of Ottawa offering sophisticated laboratory space for research on infectious agents of Risk Group 3. In view of promoting collaborative partnership, this biocontainment laboratory is available not only to uOttawa Investigators, but also to external research groups. State-of-the-art engineering controls, design and rigorous standard operating procedures allow for optimal safety of laboratory personnel, the community and the environment. Divided in two individually controlled suites of 165 m² each, it has the capacity of accommodating several research groups simultaneously.

Biosciences Complex 30 Marie-Curie Ottawa, ON, K1N 6N5 CanadaThe High-Throughput Facility is an integral part of the Centre for Catalysis Research and Innovation. The workflows within the facility were specifically designed to run a large number of reactions on very small scale in a fully-automated fashion - therefore minimizing cost, time and experimental error. Such an approach enables the user to screen a whole array of reaction conditions and narrow it down to a few potential hits in a fraction of the time and at a fraction of the cost that it would take through traditional research methods. The High-Throughput Facility encourages external academic users and collaborators; please contact us for more information.

20 Marie-Curie Ottawa, ON, K1N 6N5 CanadaLANSET is a research and training facility that supports analyses of a wide range of natural and synthetic environmental compounds. In addition to providing analytical support to CAREG, this laboratory also serves the broader Canadian and international scientific community. Guidelines for sample submission LANSET occupies one entire floor of CAREG (14 rooms), has a state-of-the-art extraction laboratory, consisting of an ultra-trace clean lab with controlled atmosphere, a state-of-the-art analytical facility which includes a wide range of mass spectrometers, including Inductively-Coupled Plasma Mass Spectrometry, triple-MS, and Time-of-Flight accurate mass capabilities. These instruments are used mainly to identify natural products and environmental contaminants in plants and environmental samples. The LANSET facility is accredited for mercury analysis by the Canadian Association for Environmental Analytical Laboratories, and specializes in radiometric analysis of natural isotopes including lead-210 and radium-226 for dating sediment and peat cores for use in paleoenvironmental reconstructions. The facility is further enhanced with sample handling, storage and tracking facilities, greenhouses, environmental growth cabinets, and herbarium. In recognition of these contributions to the broader scientific community, LANSET was awarded the status of ‘University of Ottawa Research Facility’ in 2006.

451 Smyth road, Room 4206 Ottawa, ON, K1N 8M5 CanadaWelcome to the Flow Cytometry & Virometry (FCV) Core Facility at the University of Ottawa. Our facility is located on the 4th floor in Roger Guindon Hall, room 4206. We offer high-speed cell sorting services, magnetic cell separation, bench top flow cytometry analysis as well as training, and support to the research community.

Roger Guindon Hall 451 Smyth Road Ottawa, ON, K1N 8M5 CanadaWelcome to the Proteomics Resource Centre of the Ottawa Institute of Systems Biology (OISB). Our proteomic core facility has a complete series of state-of-the art mass spectrometers. We offer the research community a complete array of proteomic services from protein and post translational modification (PTM) identification to large scale quantitative proteomics. We also participate in research collaborations. Contact Dr. Zhibin Ning for a quote for services and more information.

130 Louis Pasteur Pvt. Ottawa, ON , K1N 6N5 CanadaThe Laboratory for Physiology and Genetics of Aquatic Organisms is a core facility designed for in vivo experiments on a variety of fish and amphibian species, including zebrafish, brown ghost knifefish, gulf toadfish, goldfish, rainbow trout and other amphibian species, such as the western clawed frog and the leopard frog. The Laboratory is located in D’Iorio Hall of the Faculty of Science and comprises 15 rooms over an approximate area of 500 m². It has its own water treatment facility for dechloramination, sterilization, ionic strength and temperature adjustments. The objectives of the Laboratory are to provide state-of-the-art core facilities for: 1. The breeding and maintenance of healthy aquatic organisms. 2. Laboratory space for in vivo physiological and genetic experimentation. 3. Training and support for all users. The facility is primarily used by members of the Faculty of Science, University of Ottawa, and serves over 100 students, research trainees and scientists. Users of the Laboratory for Physiology and Genetics of Aquatic Organisms perform cutting edge experiments in the fields of cellular and molecular biology, comparative physiology, developmental biology, endocrinology, neurobiology and behaviour, and genetics.

2075 Bayview Avenue, C7 35c Toronto, ON, M4N 3M5 CanadaThe quality, speed and cost of generating and analyzing genomic data is increasingly crucial to researchers as they seek to develop personalized treatments for complex diseases like cancer and heart disease. The genomics core facility at Sunnybrook Research Institute (SRI), under the directorship of Dr. Arun Seth, makes cutting-edge genomics research not only possible, but also affordable. The genomics core facility is a centralized resource equipped with a range of next-generation instruments. Next-generation DNA sequencing: SOLiD 5500XL Ion Torrent Personal Genome Machine Nucleic acid quantification: Digital Droplet PCR system Real-time PCR system We deliver cost-effective and high-quality services and are continually updating and expanding our services to keep up with advances in technology and its applications. Our facility is open to the SRI community as well as to investigators from external institutions. We also provide opportunities for SRI research fellows, graduate students and residents to gain experience and training. We encourage collaborative opportunities with investigators on research projects and support investigators' grant applications.

Faculty of Medicine Ottawa, ON, K1N 8M5 CanadaThe mouse is a powerful mammalian biological model system due in large part to our ability to manipulate the murine genome. Indeed, transgenic and embryonic stem cell (ES cell) strategies can now be used to effect the introduction of precise, preplanned, genetic alterations of essentially any nature in the mouse genome. This allows for the precise modeling of many human disorders as well as the generation of exquisite biological models for any number of research objectives. Transgenic and ES cell-based murine models are de rigor in many areas of the biological sciences, and ready access this technology is essential to a robust and competitive research program. The Transgenic Mouse Core Facility strives to provide open access services to support these methodologies, with a mandate is to deliver transgenic and ES cell based mouse models for the University of Ottawa and associated research institutes. The facility will also provide ancillary methodologies, including embryo cryopreservation and rederivation, for more efficient management of resources.

10 Marie Curie Private Ottawa, Ontario, K1N 6N5 Canada

10 Marie-Curie Private, Ottawa, ON K1N 9A4, CA

2355 Derry Road East Mississauga, ON, L5S 1V6 CanadaUQSI is a US based international team of Pharmaceutical Consultants providing a wide range of consulting services to Pharmaceutical, Biotechnology and Active Pharmaceutical Ingredients (APIs) Industry. Our team of professionals can provide operational assistance in Quality functions, Commissioning & Qualification, Validation, cGMP Compliance, Regulatory Affairs, design and construction supervision for new plants. Our team is well experienced to meet your immediate and long term requirements of skilled biotech and pharma science trained, experienced staff.

Faculty of Medicine Ottawa, ON, K1N 6N5 CanadaThe Faculty of Medicine's 'Common Equipment and Technical Core Facility' was established to optimize technical resources and common 'shared' equipment within the Departments of BMI and CMM. The Core Facility encompasses infrastructure and technical services from both of these departments in an attempt to meet the research needs of investigators and students. It is operated by a team of 4 Technical Officers who are committed to providing quality technical assistance to faculty members and research personnel. In addition, the technical staff aims to manage and maintain the common equipment at its optimal level of performance. Most laboratories do not own the type of equipment that constitute the basic framework of the Core Facility, therefore, operating and maintaining a Common Equipment Core with 'shared' equipment that is in a state of operational readiness and peak performance is essential to the efficiency and success of every principal investigator and his/her laboratory members. Researchers therefore, depend and rely on the optimal functionality of these common scientific instruments. The equipment provided by the Core Facility allows research personnel the opportunity to use a wide variety of equipment that is well maintained, eliminating the need to purchase and maintain these pieces within individual labs. The 'Common Equipment and Technical Core Facility' can be separated into two distinctive categories: The Technical Core Services which refer to technical assistance and services provided by the technical staff.

Room 1311, Roger Guindon Hall (RGH) 451 Smyth Road Ottawa, ON, K1H 8M5 CanadaThe Behavioral Core facility was established in 2009 and provides a state-of-the-art facility equipped to serve as a time-efficient and cost-effective service for researchers in need of mouse behavioral analyses. The Behavioral Core is located within the Animal Care Vivarium at Roger Guindon Hall. The equipment enables a full battery of assays relevant to learning and memory, social behavior, sensory gating, motor function, as well as anxiety and depression. The Behavioral Core provides facilities and assistance to the research community at the University of Ottawa, its affiliated Research Institutes, as well as researchers across the Ottawa community. The Core, in collaboration with the Animal Care Committee and ACVS, can provide researchers with help in the design, execution, analysis, presentation, and interpretation of data resulting from use of the Core's facilities.

2075 Bayview Avenue, M7 231 Toronto, ON, M4N 3M5 CanadaThe High-Content Cellular Analysis (HiCCA) lab at Sunnybrook Research Institute (SRI) is a hub for automation and fluorescence applications. Directed by Dr. David Andrews, the HiCCA lab provides platforms for high-throughput and high-content investigations of in vitro model systems, and features custom-designed instrumentation and cutting-edge technologies unique to SRI. The HiCCA lab provides the tools and expertise necessary for research programs at the level of a screen, cell or molecule. Services include high-throughput confocal and widefield microscopy, fluorescence spectrophotometry, and robotics for automated workflows. Solutions offered may be full service or else involve various degrees of collaborative effort, tailored to the needs of each specific project. User training for select instrumentation is available.

25 Templeton St, Room 350 Ottawa, ON, K1N 6N5 CanadaPhotonics embraces the science and technology of light: its interaction with matter and the technology for its generation, manipulation, transmission and detection. Photonics research is revolutionising our lives like the preceding electronic and digital revolutions. Applications of photonics are diverse from communications and entertainment systems in homes to uses in biology, quantum computation, medicine, environmental sensing, green technologies and many other aspects of our everyday lives. Examples include the near-instantaneous transmission around the globe of voice, video and data on lightwaves, laser scanners reading bar codes on everything such as goods in a supermarket to luggage in airports, and surgeons utilizing lasers in surgery rather than scalpels. Despite the ubiquitous penetration of photonics, challenges remain, be they at the level of applications where, for example, improvements are continuously sought to optical telecommunications equipment, solar cells, and optical biosensors; or at the level of fundamentals where, for example, greater understanding is sought on how light interacts with matter at extreme time and spatial scales or on how quantum states of light can be formed and utilised. To meet such challenges, the University of Ottawa established the world-class Centre for Research in Photonics (CRPuO) founded on strengths within our Faculties of Engineering and Science.

25 Templeton Street, Ottawa, ON K1N, CAPhotonics embraces the science and technology of light: its interaction with matter and the technology for its generation, manipulation, transmission and detection. Photonics research is revolutionising our lives like the preceding electronic and digital revolutions. Applications of photonics are diverse from communications and entertainment systems in homes to uses in biology, quantum computation, medicine, environmental sensing, green technologies and many other aspects of our everyday lives. Examples include the near-instantaneous transmission around the globe of voice, video and data on lightwaves, laser scanners reading bar codes on everything such as goods in a supermarket to luggage in airports, and surgeons utilizing lasers in surgery rather than scalpels. Despite the ubiquitous penetration of photonics, challenges remain, be they at the level of applications where, for example, improvements are continuously sought to optical telecommunications equipment, solar cells, and optical biosensors; or at the level of fundamentals where, for example, greater understanding is sought on how light interacts with matter at extreme time and spatial scales or on how quantum states of light can be formed and utilised. To meet such challenges, the University of Ottawa established the world-class Centre for Research in Photonics (CRPuO) founded on strengths within our Faculties of Engineering and Science.

RGN 3171 451 Smyth Road Ottawa, ON , K1H 8M5 CanadaThe Cell Biology & Image Acquisition (CB&IA) Core Facility provides state-of-the-art advanced microscopes, image analysis tools, and technical support to facilitate your microscopy research. We offer consultations to determine the most appropriate microscope for your specific needs and the proper design of your experimental set-up. In addition, we provide comprehensive training and follow-up sessions for all first-time users, ensuring optimal use of the imaging systems. The CBIA Core Facility is located within Roger Guindon Hall at the University of Ottawa. Facility resources are available to all uOttawa principal investigators, as well as adjunct investigators at other institutions.

2075 Bayview Avenue, M7 301 Toronto, ON, M4N 3M5 CanadaThe Centre for Flow Cytometry and Microscopy at Sunnybrook Research Institute (SRI) houses two BD multilaser, digital, high-velocity cell sorters. We offer the following services: cell sorting cell analysis user training for the flow cytometer benchtop analyzers user training for the widefield and confocal microscopes Work is performed on a fee-for-service basis, and is available to internal and external users.

University of Toronto 160 College Street, Room 230 Toronto, Ontario, M5S 3E1 CanadaIn the late 90s, there was no human genome sequence, no wide-spread stem cell technologies, and DNA sequencing was slow and expensive. However, University of Toronto Professors Cecil Yip and James Friesen foresaw that new genomic technologies would open up massive progress in biomedical research. Anticipating the growing need for interdisciplinary approaches, they envisioned a research institute where all boundaries in research could be lifted. Thanks to an investment from the Government of Canada, the province of Ontario, private sector companies and Terrence J. Donnelly, a philanthropist with a vision, that revolutionary idea materialized into a world-renowned institute for biomedical research – the Donnelly Centre. On November 5, 2005 the Donnelly Centre for Cellular and Biomolecular Research opened its doors to world-class researchers in biology, computer science, engineering, chemistry and pharmacy under one joint roof, where they could feed off each other’s expertise and creativity to decipher the biology behind the world's most devastating diseases.

160 College Street Toronto, ON, M5S 3E2 CanadaIn the late 90s, there was no human genome sequence, no wide-spread stem cell technologies, and DNA sequencing was slow and expensive. However, University of Toronto Professors Cecil Yip and James Friesen foresaw that new genomic technologies would open up massive progress in biomedical research. Anticipating the growing need for interdisciplinary approaches, they envisioned a research institute where all boundaries in research could be lifted. Thanks to an investment from the Government of Canada, the province of Ontario, private sector companies and Terrence J. Donnelly, a philanthropist with a vision, that revolutionary idea materialized into a world-renowned institute for biomedical research – the Donnelly Centre. On November 5, 2005 the Donnelly Centre for Cellular and Biomolecular Research opened its doors to world-class researchers in biology, computer science, engineering, chemistry and pharmacy under one joint roof, where they could feed off each other’s expertise and creativity to decipher the biology behind the world's most devastating diseases.

2075 Bayview Avenue Toronto, ON, M4N 3M5 CanadaIn this facility, research teams are making new biological agents for cell-based therapies and vaccines that target dysfunctional immune systems, heart disease and cancer. Having immediate access to this strictly controlled environment ensures that quality is built into each step of the cell design and manufacturing process. This guarantees that products developed in the lab are safe, pure and effective for clinical testing. Building this lab will help move preclinical findings—such as the landmark discovery by Dr. Juan Carlos Zúñiga-Pflücker of how to generate stem cells in the lab, and coax them into becoming mature T cells, toward rebuilding damaged immune systems—faster and more efficiently to the clinic. Sunnybrook Research Institute is at the forefront of inventing methods and technologies to generate new cell types from stem cells or other stem-cell-like cells, and to re-educate cells. With this facility, we are taking it up a significant notch; our biological scientists, who are developing preclinical models, are working with clinicians-scientists, who can test the efficacy of these models in patients. Similarly, imaging scientists who have developed ways to track and evaluate the efficacy of these cells in preclinical models are interacting with clinician-scientists to track and evaluate the efficacy of these cell therapies in patients. In each case, the cGMP lab is an essential step in the translational research process.

451 Smyth Road Ottawa, ON , K1H 8M5 CanadaThe Cell Biology & Image Acquisition (CB&IA) Core Facility provides state-of-the-art advanced microscopes, image analysis tools, and technical support to facilitate your microscopy research. We offer consultations to determine the most appropriate microscope for your specific needs and the proper design of your experimental set-up. In addition, we provide comprehensive training and follow-up sessions for all first-time users, ensuring optimal use of the imaging systems. The CBIA Core Facility is located within Roger Guindon Hall at the University of Ottawa. Facility resources are available to all uOttawa principal investigators, as well as adjunct investigators at other institutions.

2075 Bayview Avenue, S4 408 Toronto, ON, M4N 3M5 CanadaThe histology facility at Sunnybrook Research Institute (SRI) is a full-service support lab that provides histology services for SRI researchers and external customers. It is equipped with an automated tissue processor, autostainer, embedding station, motorized microtome, cryomicrotome and vibratome. It offers paraffin services to the SRI community as well as to investigators from external institutions. Services include the following: processing decalcification paraffin embedding sectioning routine staining special staining cryosectioning vibratoming

2075 Bayview Avenue, M6 603 Toronto, ON, M4N 3M5 CanadaSunnybrook Research Institute’s Toshiba Aquilion One computed tomography (CT) scanner is a state-of-the-art imaging system used to evaluate structure and function within the human body and animal models. Research at this facility involves development of the basic physics and engineering underlying CT technology, and includes clinically motivated imaging studies involving volunteers and preclinical studies that enhance knowledge toward improving health care. The facility accommodates a wide variety of scientific projects, usually performed in collaboration with SRI investigators. It operates on a cost-recovery basis through the collection of user fees. Research at this facility is predominately conducted by researchers in Physical Sciences and their collaborators. There are also a smaller number of CT users who use the facility independent of Physical Sciences collaborations, or in their role as support personnel in the labs of collaborating scientists. Users must meet the CT research operator training requirements.

Faculty of Medicine Ottawa, ON, K1N 8M5 CanadaPre-clinical Imaging Welcome to the pre-clinical imaging facility, sponsored in part by funding from the Canadian Foundation for Innovation. This state-of-the-art imaging facility includes MRI, optical, and ultrasound imaging equipment.

Toronto, ON, M5S 3G9 CanadaThe Institute of Biomaterials & Biomedical Engineering (IBBME) at the University of Toronto is a unique, multidisciplinary research unit where investigators from engineering, medicine and dentistry collaborate to find innovative solutions for the world’s most pressing health-care challenges.

17-689 Warden Ave Toronto, Ontario, M1L 4R6 CanadauFluidix produces microfluidic devices. We provide large volume manufacturing of Microfluidic chips as well as custom fabrication of low-medium volume microfluidic platforms. Microfluidics technology is used to process nano-micro litere amount of fluid inside microchannels in the microfluidic device.

101 College Street, Suite 150 Heritage Building, MaRS Centre Toronto, Ontario, M5G 1L7 CanadaUHN Research is Canada's largest research hospital with a proud history of innovative research and discoveries. UHN Research enterprise is rooted in a robust and efficient infrastructure that has enabled the organization to achieve worldwide recognition. Through a comprehensive suite of services, UHN Research is enabling academic, clinical, and industry clients to access UHN Research's integrated resources, state-of-the-art instruments, and innovative technologies to support a multitude of research studies.

101 College Street, Suite 150 Heritage Building, MaRS Centre Toronto, Ontario, M5G 1L7 CanadaUHN Research is Canada's largest research hospital with a proud history of innovative research and discoveries. UHN Research enterprise is rooted in a robust and efficient infrastructure that has enabled the organization to achieve worldwide recognition. Through a comprehensive suite of services, UHN Research is enabling academic, clinical, and industry clients to access UHN Research's integrated resources, state-of-the-art instruments, and innovative technologies to support a multitude of research studies.

190 Elizabeth Street R Frasier Elliot Building Toronto, ON, M5G 2C4 CanadaUHN Research is Canada's largest research hospital with a proud history of innovative research and discoveries. UHN Research enterprise is rooted in a robust and efficient infrastructure that has enabled the organization to achieve worldwide recognition. Through a comprehensive suite of services, UHN Research is enabling academic, clinical, and industry clients to access UHN Research's integrated resources, state-of-the-art instruments, and innovative technologies to support a multitude of research studies.

Medical Science Building 1 King's College Circle, Room 1239 Toronto, Ontario, M5S 1A8 CanadaThe Microscopy Imaging Laboratory (MIL) is a core imaging service in the Temerty Faculty of Medicine at the University of Toronto providing electron microscopy and fluorescence microscopy imaging capabilities to students and scientists in basic, medical and industrial research. The MIL maintains a complete lab for the preparation of TEM and SEM samples including fixation, resin embedding, thin sectioning, critical point drying and gold sputter coating. The thin sectioning lab is equipped with an RMC MT7000 and two Reichert Ultracut E ultra-microtomes. A server/workstation lab is equipped with BitPlane, AutoQuant and Zen image analysis software. Operation of the unit is on a fee for service basis. Users can take advantage of full service (all work carried out by staff in the unit) or may be trained to use the equipment themselves on an hourly or annual contract fee basis.

2255 St. Laurent BlvdVinCro Clinical Management Services offers clinical research services including trial management, regulatory affairs, data management, medical monitoring, and biostatistics.

993 Princess Street, Suite 113, Kingston, ON K7M 1H3 CanadaVitaPharma offers a wide range of custom solutions for the life sciences industry. We have the ability to create limitless custom formulations, produced exclusively for your company, blended to your precise specifications or industry standards.

14, 45 Dalkeith Dr. Brantford, ON N3P 1M1 CanadaVibrant Pharma offers a full range of services in custom organic synthesis, process development, route scouting and selection, building blocks, kinase focused libraries, heterocyclic building blocks, nucleosides and nucleoside phosphoramidites, prodrug synthesis, polymorph screening and stability studies of API and intermediates.

120 Carlton Street, Toronto, ON M5A 4K2, CACanCog is a contract research organization providing non-invasive research and development services in the companion animal market. For over 10 years, the world’s leading veterinary medicine and pet food developers have trusted CanCog scientists to help guide and conduct innovative research, from early proof-of-concept evaluations through to planning and executing full scale clinical studies. CanCog research services help generate the scientific evidence needed to support product claims and regulatory submissions. CanCog scientists and veterinarians are leading experts in the field of cognition and general behavior, anxiety, aging and life-span development. Cancog is also uniquely equipped to evaluate products for osteoarthritis, cancer and metabolic disorders, and can empower studies with state-of-the-art imaging capabilities including MRI, PET/CT and DEXA. CanCog's mission is to help evaluate and develop innovative products which improve the quality of life of companion dogs and cats. We invite you to learn more about how CanCog services can help you successfully develop your next product.

1909 Maple Manor Road ON, N0B CanadaIn 1989 Vaughn Agricultural Research Services Ltd. (VARS) began operations to provide independent research services to the crop protection industry. Since then, we have conducted trials for over forty Canadian and international companies. These trials have contributed to the successful registration and launch of over fifty new active ingredients into the extensive Canadian market. We have grown by providing and increasing our range of precise, reliable and innovative research and development services. These services are designed to meet strict controls and guidelines, employing the latest technologies and scientific advances. Why? Because you don’t need registration problems. You need solutions - Solutions that Register™.

585 University Avenue Toronto, ON USAVeritas Therapeutics specializes in commercialization for the Toronto Transplant Institute and offers scientific development for immunology, biodevelopment, protein expression/purification, analytical chemistry, autoimmune disease, and animal models of disease.

61 Stonehenge Crescent Toronto, ON, M1G 2P5 Canada

102, 334Donalnds Avenue, Toronto, ON M4J3R9, Canada Canada Toronto, ON, M4J3R9 Canada

350 Tweedsmuir Avenue Ottawa, Ontario, K1Z 5N4 CanadaVirica has developed a library of Viral Sensitizers (VSE™) that help to reduce these antiviral defenses during production. VSEs alter cellular signaling and dampen antiviral defenses. This unlocks the potential for higher yields, consistent scaleup, and improved critical quality attributes (CQAs) based on application. VSEs are patented small molecules, including known drugs and novel synthetic compounds, that transiently attenuate antiviral pathways in cells thus enhancing virus production. VSEs are a simple additive introduced at time of infection or transfection and leaves no residual trace after purification.

1125 Colonel dr Ottawa, Ontario, K1S 5B6 CanadaVirica has developed a library of Viral Sensitizers (VSE™) that help to reduce these antiviral defenses during production. VSEs alter cellular signaling and dampen antiviral defenses. This unlocks the potential for higher yields, consistent scaleup, and improved critical quality attributes (CQAs) based on application. VSEs are patented small molecules, including known drugs and novel synthetic compounds, that transiently attenuate antiviral pathways in cells thus enhancing virus production. VSEs are a simple additive introduced at time of infection or transfection and leaves no residual trace after purification.

ON CanadaWadjet Consulting provides consulting for drug research compliance, quality, and regulatory services.

2 Bloor Street West Suite 700 Toronto M4W 3R1In working with WilsonHCG as your recruitment outsourcing company, expect a full-service recruitment process experience like no other.

610 Ford Drive, Suite 101, Oakville, Ontario, Canada L6J 7W4White Owl Global Services provides consulting services for the pharmaceutical, biotechnology and nutritional health industries.

1151 Richmond Street London, Ontario, N6A 3K7 CanadaAnimal Research at Western University and its affiliates is regulated by the University Council on Animal Care (UCAC) and its working group, the Animal Care Committee (ACC). These groups are supported by the Animal Care and Veterinary Services department of Western who supplies veterinarians, animal care technicians, managers and office staff to service and facilitate Western's research community throughout London in ethically-sound and ground-breaking research using animals. ACVS is dedicated to moving safe and ethical animal research forward for Western and its affiliates by offering the following services: Managing three on-campus facilities Animal Use Protocol processing for the ACC Mandated Animal User Training Institutional-and-affiliate-wide research support Facilitation and Support for Western's Animal Research Database Management Software, eSirius

4-77 Auriga Dr, Ottawa, ON, K2E 7Z7n the past 23 years, we have developed strong relationships with manufacturers of raw materials from Europe, India, China, US, South America and Japan. We can source and provide hard to find ingredients at cost effective prices. We differentiate from others by emphasising on professional service and quality products, and by focusing on value creation for our customers. Our portfolio of high quality Nutraceuticals Ingredients consists of Botanical Extracts and Powders, Specialty Ingredients, Amino Acids and Derivatives, Minerals, Vitamins, Sweeteners, Proteins, Enzymes and Blends, Vitamins and Blends, Excipients, Essential and Carrier Oils. We also stock substantial quantities of Whey Protein Concentrate, Whey Protein Isolate, Creatine Monohydrate, L-Glutamine and Branched Chain Amino Acids. In the over the counter (OTC) and prescription (Rx) segments we represent many active pharmaceutical ingredient (API) manufacturers from India, China, and Taiwan as well as Western and Eastern Europe. In addition to the products listed on our site, we can source a wide range of specialized materials and formulations through our international network of suppliers. We act as a one stop shop by providing non-ingredient sourcing solutions such as packaging items, ranging from HDPE and PET packers and jars, to liquid and powder flavours. Our distribution network covers entire North America through a network of 8 warehouses in Quebec, Ontario, Manitoba, British Columbia, New Jersey, Denver and Chicago. Our distributed operations enable us to deliver smallest to the largest orders efficiently and cost effectively.

4520 Dixie Road Mississauga ON L4W 1N2 CanadaAllied Research International provides clinical trials, early/late stage development, regulatory affairs, and bioanalytical techniques.

Toronto, ON CanadaApplied Molecular Profiling Laboratory offers cytomics, genomics, pharmcokinetic and xenograft services.

610 University Ave, 7-624 Toronto, ON, Canada M5G 2M9Applied Molecular Profiling Laboratory offers cytomics, genomics, pharmcokinetic and xenograft services.

37 Merganser Drive, Guelph ON, N1C 1E2, CanadaArthroteq is a small pre-clinical research and histology services provider with a focus on bone and joint disease, inflammation, and neuropathic pain. Our expertise and services include research study design; protocol development; validation studies; PK&PD studies; efficacy studies for osteoarthritis, osteoporosis, tendon/ligament repair, cartilage repair, and bone (spinal fusion, critical size defect, ectopic, etc.).

Glencameron Road 81 Thornhill, Ontario L3T 1N8 CanadaAlanza is a manufacturer of products for the pharmaceutical, biopharmaceutical, and biotechnology industries.

120 Carlton Street, Suite 408 Toronto, Ontario, Canada M5A 4K2Attix Pharmaceuticals offers supply of raw materials and specializes in the development and manufacturing of nutraceutical products.

22 McCurdy Road Guelph, ON N1G 4Z9 CanadaArking Pharma Scientific is a leading Active Pharmaceutical Ingredients (APIs) and intermediates manufacturing and services company.

700 Bay street, Suite 1100 Toronto Ontario M5G 1Z6 CanadaACGT offers DNA synthesis, DNA sequencing and DNA analysis services.

20 Cutten Place Guelph Ontario N1G 4Z7Founded in 1980 by Irish biochemist and entrepreneur Dr. Pearse Lyons, Alltech is a leading global biotechnology company whose mission is to improve the health and performance of people, animals and plants through natural nutrition and scientific innovation. We pursue this mission guided by what we call the ACE principle, our promise that in doing business we have a positive impact on the Animal, the Consumer and the Environment. Animal Health Our core business improves animal health and performance by adding nutritional value to feed, naturally, through Alltech’s innovative use of yeast fermentation, enzyme technology, algae and nutrigenomics, which studies the impact of nutrition at the genetic level. Our technologies and support programs enable farmers to realize greater efficiency, profitability and sustainability on their farms. Alltech Crop Science Our Alltech Crop Science division complements our animal nutrition business by focusing on improving the health of crops. Our technologies enable us to improve the productivity of the field, in terms of yield quality and quantity, and to enhance nutrition beginning with the soil and the seed. Human Health We believe scientific innovation in animal and crop sciences is part of a much more important story, that of human health. Healthier animals and crops, nurtured naturally through Alltech’s nutritional solutions, affect human well-being. For example, fruits, vegetables and animal proteins have become less nutrient-rich in the past half-century. From fish to oranges, you need to eat more today to get the same nutritional value. Our work within animal and crop sciences is restoring value and also exploring ways to naturally enrich foods through improving the animal diet or crop produced. For example, laying hens fed a diet rich in Alltech’s algae produce eggs enriched with DHA omega-3, an essential nutrient for human cognitive development and health at all ages.

480 University Avenue Suite 910 Toronto Ontario M5G 1V2 CanadaAxela Biosensors offers a unique portfolio of next generation, commercial stage, multiplex tools that provide enhanced analysis of proteins, DNA and RNA.

2224 Walker Rd., #300 Windsor, Ontario N8W 5L7Windsor Clinical Research Inc. (WCR Inc.) is an independent research site focused on the conduct of human clinical trials in dermatology. We are dedicated to providing our sponsors with timely recruitment and completion of trials in state of the art professional facilities with qualified, caring staff. We have a broad range of experience in phase II – IV clinical trials for conditions including acne, alopecia, actinic keratoses, atopic eczema, rosacea, herpes, leg ulcers, and psoriasis. Led by an internationally recognized physician with extensive experience in protocol development and clinical trials, Windsor Clinical Research partners with sponsors to implement and complete trials efficiently to advance development of their products. Our staff are GCP and HazMat certified. We take pride in the quality of our work and continuously strive to assist remarkable companies that create outstanding products, treatments and services to improve patient health and quality of life.

2224 Walker Rd, Windsor, , ON , N8W 5L7 CanadaWindsor Clinical Research Inc. (WCR Inc.) is an independent research site focused on the conduct of human clinical trials in dermatology. We are dedicated to providing our sponsors with timely recruitment and completion of trials in state of the art professional facilities with qualified, caring staff. We have a broad range of experience in phase II – IV clinical trials for conditions including acne, alopecia, actinic keratoses, atopic eczema, rosacea, herpes, leg ulcers, and psoriasis. Led by an internationally recognized physician with extensive experience in protocol development and clinical trials, Windsor Clinical Research partners with sponsors to implement and complete trials efficiently to advance development of their products. Our staff are GCP and HazMat certified. We take pride in the quality of our work and continuously strive to assist remarkable companies that create outstanding products, treatments and services to improve patient health and quality of life.

400 Iroquois Shore Road Oakville, ON, L6H 1M5 CanadaWellSpring Pharma Services (www.wellspringcmo.com) provides turn-key services for small to mid-sized pharmaceutical companies to manufacture and package their solid, semi-solid, and non-sterile liquid products at our cGMP, FDA and HC inspected facility based near Toronto. We offer fast, flexible, and concierge manufacturing services from late clinical to commercial scale.

50 Ronson DriveAxela provides automated microarray system for hybridation, detection, reporting, and multiplex test services.

CAN-AM Cryoservices 1057 Main St. W. Suite 102 Hamilton, Ontario, L8S 1B7

ReproMed 56 Aberfoyle Crescent Suite 300 Toronto, Ontario, M8X 2W4

Outreach Health Services 16945 Leslie Street Unit #8 Newmarket, Ontario L3Y 9A2

101 College St, Ste 700 Toronto, Ontario, M5G 1L7 CanadaYCharOS Inc. is a Canadian, public interest, open science company with the mission of characterizing commercially available reagent antibodies for every human protein.

175 Longwood Rd South Hamilton, Ontario, L8P 0A1 CanadaYordas Group is a leading provider of scientific, environmental, human health, global regulatory, sustainability and product stewardship consulting services. Yordas has a solid and internationally recognised reputation as a provider of training, advice and services to ensure compliance across the globe, with regional representation and service providers in Europe, the Americas and Asia Pacific.

49 National Pine Dr. Toronto, ON L6A 3M3 CanadaZL Interpharm specializes in anesthetics, vaccines, fluorochemicals, disinfection, and water purification products.

829 Covehead Crescent Ottawa, ON K1V 1M3 Canada3D Healthcare Consulting (3DHC) specializes in healthcare education.

316 Edgeley Blvd Concord, Ontario Canada, L4K 3Y3A&K Petrochem is one of the leading suppliers in the chemical distribution business across Canada and has represented many major manufacturers around the world since 1971.

Toronto, ON, CanadaAmbit offers kinase profiling and assay development services.

2125 Ambassador Drive Windsor, Ontario N9C 3R5 CanadaAccucaps offers pilot development, full-scale production, and soft-gelatin capsule manufacturing.

11B Nicholas Beaver Rd. RR3 Guelph, ON N1H 6H9, CanadaAquaTox Testing & Consulting offers toxicity testing, ligand modelling, metal speciation, and tests for biodegradability and microbial respiration.