526 South Main St suite 714.G Akron OH 44311 USAAlphelys offers tissue repository systems, preservation, pathology, cytogenetics, tissue arrays, and sample collection software.

100 Science Village 1381 Kinnear Road Columbus, OH 43212Applied Biomolecular Technologies offers genetic engineering and a range of protein services.

2887 Gilchrist Rd. Akron, OH 44305 USAAkron Rubber Development Laboratory offers analytical chemistry services including FTIR, HPLC, TLC, and UV spectroscopy analysis.

2851 Gilchrist Rd. Akron, Ohio 44305Akron Rubber Development Laboratory offers analytical chemistry services including FTIR, HPLC, TLC, and UV spectroscopy analysis.

300 Kenmore Blvd. Kenmore, Ohio 44301Akron Rubber Development Laboratory offers analytical chemistry services including FTIR, HPLC, TLC, and UV spectroscopy analysis.

434 W. Dussel Dr. Maumee, , OH , 43537 Well regarded as top performers for membrane protein structural biology, Anatrace products are chosen for their uniquely pure molecules – and the exacting chemistry behind them. From compounds designed to disrupt cell membranes to products that stabilize or solubilize unstable macromolecules and proteins, we’re always raising the bar.

434 W. Dussel Dr. Maumee, OH 43537 Well regarded as top performers for membrane protein structural biology, Anatrace products are chosen for their uniquely pure molecules – and the exacting chemistry behind them. From compounds designed to disrupt cell membranes to products that stabilize or solubilize unstable macromolecules and proteins, we’re always raising the bar.

6201 Trust Dr, Ste B Holland, OH, 43528 United States Well regarded as top performers for membrane protein structural biology, Anatrace products are chosen for their uniquely pure molecules – and the exacting chemistry behind them. From compounds designed to disrupt cell membranes to products that stabilize or solubilize unstable macromolecules and proteins, we’re always raising the bar.

2000 Old Byers Road Miamisburg, OH 45342

Abbott Nutrition 625 Cleveland Avenue Columbus, Ohio 43215Abbott Laboratories offers contract manufacturing and API synthesis services.

Solon, OH, 44139 United StatesAMRESCO supplies research products, including DNA and RNA reagents, buffers, detection kits, and labeling supplies.

AMRESCO Inc. 6681 Cochran Road Solon, OH 44139 USAAMRESCO supplies research products, including DNA and RNA reagents, buffers, detection kits, and labeling supplies.

3615 Superior Avenue, Suite 4407B Cleveland, OH 44114Analiza provides physicochemical services, including thermodynamic or kinetic solubility, Log D, pKA, crystallinity assessment (XRD), and fragment based screening.

12300 Kinsman Road, Suite F2 P.O. Box 304 Newbury, OH, 44065 United StatesTake advantage of our 10+ years of industrial and academic experience in surface and interface science Whether you have adhesion or printing problems, pigment or pharmaceutical powder dispersability issues, want to improve your emulsifiers, need to know how much surfactant is optimal to prevent denaturing during protein processing, just want some accurate surface energy values for your surfaces, or have any other surface/interface related problems - GIVE US A CALL We have the analytical tools and the expertise to study your problems, and find solutions. Most analytical work is complete in under two weeks - although long term contracts are also available for large projects. Confidentiality is always maintained, and the costs are very reasonable (basic price lists are provided under "Contract Laboratory Services" above) Surface chemistry seminars (at our site or yours) are also available, as are instrument training courses for many types of tensiometers and contact angle meters

1425 Plain City-Georgesville Rd BLDG JM-10 West Jefferson, OH, 43162 United StatesAmplifyBio’s safety, efficacy, and toxicology unit (ASET) was launched as a preclinical CRO that spun out of Battelle 2021 to be commercially focused and meet the needs of modern drug development with speed and agility. AmplifyBio brings decades of experience to accommodate a wide variety of GLP and non-GLP studies in all species and dose routes. Among the investments that AmplifyBio has made to empower preclinical assessments is building a new state-of-the-art analytical laboratory to include molecular and immunological assays that assess critical safety and efficacy indicators for cell and gene therapies during in vivo studies. Additional investments in digital pathology, capacity optimization, and real-time data solutions ensure that AmplifyBio is the most responsive, collaborative, problem-solving partner in the preclinical CRO marketplace. Clients have direct access to our experts throughout the study, including the Study Director, dedicated Program Manager, and Business Account Manager, allowing for consistent communication and nimble decision-making. AmplifyBio is aware of how critical timelines are in the drug development process and is proud to have established and maintained a 99% on-time reporting record for commercial clients.

Bowling Green, OH, 43403 United StatesThe Biology Greenhouse is located on the campus of Bowling Green State University in Bowling Green, Ohio. Frank Schemenauer is the Horticulturist in charge of these facilities. The greenhouse facility has four houses. Two of the greenhouses are used for research and class projects. The remaining two houses hold the teaching collections, which include a desert area and a tropical floor planting. The greenhouse is open for school tours K through 12. Visitation by the general public is welcome. Hours can change each semester, so anyone may call 1-419-372-2375 for information or to arrange visiting times.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403The Biology Greenhouse is located on the campus of Bowling Green State University in Bowling Green, Ohio. Frank Schemenauer is the Horticulturist in charge of these facilities. The greenhouse facility has four houses. Two of the greenhouses are used for research and class projects. The remaining two houses hold the teaching collections, which include a desert area and a tropical floor planting. The greenhouse is open for school tours K through 12. Visitation by the general public is welcome. Hours can change each semester, so anyone may call 1-419-372-2375 for information or to arrange visiting times.

Bowling Green, OH, 43403 United StatesThrough outreach into the community, as well as on campus, the mission of the Herpetology lab is to incorporate the core values of Bowling Green State University while promoting appreciation of biological diversity and the understanding and respect of organisms encountered through the field of Herpetology. Volunteer work in the lab, providing hands-on demonstrations and lectures comprise our effort in encouraging respect in peoples reaction to reptiles while educating as well. Research utilizing proper reptile husbandry is encouraged in the same manner that all student-designed research is encouraged in the Department of Biological Sciences at BGSU. The Herpetology lab is committed to the learning that comes from hands-on experience.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403Through outreach into the community, as well as on campus, the mission of the Herpetology lab is to incorporate the core values of Bowling Green State University while promoting appreciation of biological diversity and the understanding and respect of organisms encountered through the field of Herpetology. Volunteer work in the lab, providing hands-on demonstrations and lectures comprise our effort in encouraging respect in peoples reaction to reptiles while educating as well. Research utilizing proper reptile husbandry is encouraged in the same manner that all student-designed research is encouraged in the Department of Biological Sciences at BGSU. The Herpetology lab is committed to the learning that comes from hands-on experience.

Cleveland, OH United StatesBioInVision offers high-resolution, large field-of-view microscopic imaging, 3D reconstruction, and specialized image processing and analysis capabilities

781 Beta Dr. Ste E Cleveland, OH 44143 USABioInVision offers high-resolution, large field-of-view microscopic imaging, 3D reconstruction, and specialized image processing and analysis capabilities

300 Northfield Rd. Bedford OH 44146Ben Venue Laboratories offers lyophilized sterile products, process development, clinical material manufacturing, and commercial production.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403The Biology Department has two graduate computer labs in the Life Sciences Building. The labs provide over a dozen computers that include Dell PCs and Apple iMacs with wide screens suitable for bioinformatics, genomics, molecular modeling, and GPS mapping activities. Students find that these rooms are a quiet place to work where they have access to the internet and a dedicated laser printer. In addition to the computer rooms in the Life Sciences Building there are many additional computer facilities on campus. These include labs for classroom instruction, open labs, and high-end graphics and multimedia labs. Please consult the BGSU Information Technology Services for further details.

Bowling Green, OH, 43403 United StatesWelcome to our archive of 185+ digitized images. Note: Any image may be freely used for educational and noncommercial purposes, however, we do reserve all commercial rights.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403Welcome to our archive of 185+ digitized images. Note: Any image may be freely used for educational and noncommercial purposes, however, we do reserve all commercial rights.

4150 Tuller Rd., Ste 228 Dublin, OH 43017 USAbioWORLD offers antibody production, DNA/RNA synthesis, peptide synthesis, 2D gel analysis, cloning, protein expression, and library construction products and services.

217 Life Science Building Room 336 Bowling Green State University Bowling Green, Ohio 43403WELCOME! The Bowling Green State University Center for Aquatic Ecology offers an online resource for the public as well as students. Aquatic life identification resources with a focus on species found in Northwest Ohio can be found through this identification link. This page is the "Gateway" to a listing of over 185 species featuring digitized images, drawings and information on fish and other aquatic organisms. The information may be freely used for educational and noncommercial purposes, however, we reserve all commercial rights. A number of undergraduate and graduate students pursue research through the Aquatic Ecology Lab under Dr. Jeff Miner's oversight. The general focus of the Lab is the ecology of Lake Erie, but studies in other areas and disciplines are represented as well. Visit his web page for more information on the related research.

Bowling Green, OH, 43403 United StatesIn the marine lab, eight major phyla are represented in over 66 genera of marine life including sea anemones, corals, starfish, sea urchins, snails, crabs, lobsters, and algae as well as a wide variety of marine fish. The animals in the lab are maintained by students mainly for class study and research projects, but are also present for the appreciation of visitors and other students. Students interested in aquatic or marine biology are encouraged to get involved right away and maintain a tank in the marine laboratory on a volunteer basis. The students are then urged to take the closed systems course (Biology 370) to integrate the theory of animal management with marine research. Once this has been completed, the students are prepared for more aquatic or marine courses that may ultimately lead to summer internships at marine institutions. The most serious students may choose to conduct research with one of BGSU's researching faculty. Additional experience can be gained with field study during the summer at the Gulf Coast Research Laboratory in Mississippi or Stone Lab in Lake Erie. Both are affiliated with B.G.S.U. Additional field experience is available at other coastal labs and possibly on research cruises. The B.G.S.U. Marine Laboratory is located on the second floor of the Life Science building and is open to anyone wishing to view the animals or talk with the students. It is open during normal working hours and on weekends when arranged in advance. Large groups are welcome but are requested to call in advance so arrangements can be made for a tour.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403In the marine lab, eight major phyla are represented in over 66 genera of marine life including sea anemones, corals, starfish, sea urchins, snails, crabs, lobsters, and algae as well as a wide variety of marine fish. The animals in the lab are maintained by students mainly for class study and research projects, but are also present for the appreciation of visitors and other students. Students interested in aquatic or marine biology are encouraged to get involved right away and maintain a tank in the marine laboratory on a volunteer basis. The students are then urged to take the closed systems course (Biology 370) to integrate the theory of animal management with marine research. Once this has been completed, the students are prepared for more aquatic or marine courses that may ultimately lead to summer internships at marine institutions. The most serious students may choose to conduct research with one of BGSU's researching faculty. Additional experience can be gained with field study during the summer at the Gulf Coast Research Laboratory in Mississippi or Stone Lab in Lake Erie. Both are affiliated with B.G.S.U. Additional field experience is available at other coastal labs and possibly on research cruises. The B.G.S.U. Marine Laboratory is located on the second floor of the Life Science building and is open to anyone wishing to view the animals or talk with the students. It is open during normal working hours and on weekends when arranged in advance. Large groups are welcome but are requested to call in advance so arrangements can be made for a tour.

Bowling Green, OH, 43403 United StatesThe Herbarium at the Department of Biological Sciences contains over 20,000 specimans from Ohio and neighboring states. One of the highlights is the Mosely collection featuring numerous pre-1900 specimens documenting segments of the pre-settlement vegetation of northwest Ohio.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403The Herbarium at the Department of Biological Sciences contains over 20,000 specimans from Ohio and neighboring states. One of the highlights is the Mosely collection featuring numerous pre-1900 specimens documenting segments of the pre-settlement vegetation of northwest Ohio.

Bowling Green, OH, 43403 United StatesThe Microbiology Prep Room is located in room 531A Life Science Building at Bowling Green State University. The facility supports both undergraduate classes and research laboratories in the Biological Sciences Department. The Prep Room maintains records as required by the Ohio EPA for the storage, treatment, and disposal of Infectious waste. All infectious waste produced by the biology, chemistry and other departments on campus are treated here.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403The Microbiology Prep Room is located in room 531A Life Science Building at Bowling Green State University. The facility supports both undergraduate classes and research laboratories in the Biological Sciences Department. The Prep Room maintains records as required by the Ohio EPA for the storage, treatment, and disposal of Infectious waste. All infectious waste produced by the biology, chemistry and other departments on campus are treated here.

Bowling Green, OH, 43403 United StatesBowling Green State University is at the western end of Lake Erie, and in close proximity to remnant oak-savanna prairies (Oak Openings Region) and fragmented forest-agroecosytem complexes. The Biology department also has an Ecology Research Station, which is 15 enclosed acres with aquatic and terrestrial areas for research and teaching just north of the BG airport at 16750 Mercer Rd. Shown below are some additional pictures taken at the field station.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403Bowling Green State University is at the western end of Lake Erie, and in close proximity to remnant oak-savanna prairies (Oak Openings Region) and fragmented forest-agroecosytem complexes. The Biology department also has an Ecology Research Station, which is 15 enclosed acres with aquatic and terrestrial areas for research and teaching just north of the BG airport at 16750 Mercer Rd. Shown below are some additional pictures taken at the field station.

Bowling Green, OH, 43403 United StatesThe Scanning Electron Microscope (SEM) is used in many fields of science. A biologist might use it to study the tiniest structures of an insect, the geologist might use it to learn what chemicals are present in a rock, and the automobile engineer might use it to find tiny defects in a car part. SEM images are created using electrons instead of the photons of light we use to see the world around us. Electrons have a shorter wavelength than photons allowing much greater magnifications and resolution than with conventional light microscopy. n the SEM, the most common images are made by bombarding a specimen with a narrow beam of electrons and scanning that beam back and forth across the surface of the specimen. A Transmission Electron Microscope (TEM) is used if even higher magnifications are needed. A biologist might use it to study the membrane of an organelle. The chemist might use it to identify a crystalline substance. A crystalline structure can be determined by studying the patterns of electron diffraction made when the electron beam goes through an ultra-thin crystal.

217 Life Science Building Bowling Green State University Bowling Green, Ohio 43403The Scanning Electron Microscope (SEM) is used in many fields of science. A biologist might use it to study the tiniest structures of an insect, the geologist might use it to learn what chemicals are present in a rock, and the automobile engineer might use it to find tiny defects in a car part. SEM images are created using electrons instead of the photons of light we use to see the world around us. Electrons have a shorter wavelength than photons allowing much greater magnifications and resolution than with conventional light microscopy. n the SEM, the most common images are made by bombarding a specimen with a narrow beam of electrons and scanning that beam back and forth across the surface of the specimen. A Transmission Electron Microscope (TEM) is used if even higher magnifications are needed. A biologist might use it to study the membrane of an organelle. The chemist might use it to identify a crystalline substance. A crystalline structure can be determined by studying the patterns of electron diffraction made when the electron beam goes through an ultra-thin crystal.

Battelle 505 King Ave. Columbus, OH 43201-2693Battelle is a GLP-compliant, IND and BLA-enabling CRO. We provide services that can help move projects from in vitro to in vivo through clinical support. Specifically, our core capabilities are focused around our long-standing experience and expertise in cell-based and biochemical assay development, validation and analytical and bioanalytical sample screening, proteomics, compound synthesis, HTP next generation sequencing, in vivo efficacy, safety pharmacology, toxicology, inhalation toxicology (small and large species), ADME/PK, analytical chemistry, pathology. Battelle also has deep experience developing and manufacturing medical devices, and in conjunction with customer test articles is able to validate both the device and test article together.

10999 Reed Hartman Highway, Suite 304B,Cincinnati, OH 45242, USA. Cincinnati, Ohio, 45242 United StatesA leading manufacturer and supplier with more than 80,000 compounds in stock, scale-up manufacture, and custom services. With a wide range of ISO-certified laboratory chemicals, from heterocycles, boron acids, amino acids, and metal catalysts to chiral compounds, BLDPharm is ready for worldwide shipping.

IDA Business & Technology Park, Loughrea, Co Galway, IrelandChanelle offers services in manufacturing veterinary products as well as R&D, registration and sale of generic dossiers, contract manufacturing and contract packaging of human pharmaceuticals.

700 Children's Drive Columbus, OH, 43205 United StatesThe Biospecimen Core Resource (BCR) is a CAP-accredited laboratory and biorepository within the Biopathology Center (BPC) at Nationwide Children’s Hospital. The BCR supports multiple cancer genomics projects such as The Cancer Genome Atlas (TCGA), Cancer Driver Discovery Project (CDDP), HIV+ Tumor Molecular Characterization Project (HTMCP) and Burkitt Lymphoma Genome Sequencing Project (BLGSP), Therapeutically Applicable Research to Generate Effective Treatments (TARGET), Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials (ALCHEMIST) and Exceptional Responders (ER) Initiative.

10900 Euclid Avenue Cleveland, OH, 44106 United StatesThis core provides access to instrumentation to perform cell based assays and cell sorting. Trained users schedule time on instruments, then come to the facility and run their own samples. Core staff are on-site to help if difficulties arise. In special cases, samples can be run by Core staff by prior arrangement. The core operates on a cost recovery basis. Prior to access, users need to supply a valid account that will be charged at the end of the month of access. Sometimes it is more expedient or necessary to use other available Cytometry and Microscopy cores. We fully support this and cooperate with facilities for cytometry - Center for AIDS Research, Infectious Diseases, LRI Flow Cytometry Core, and microscopy - CWRU SOM Neurosciences and the Lerner Research Institute.

10900 Euclid Ave., Cleveland, Ohio 44106This core provides access to instrumentation to perform cell based assays and cell sorting. Trained users schedule time on instruments, then come to the facility and run their own samples. Core staff are on-site to help if difficulties arise. In special cases, samples can be run by Core staff by prior arrangement. The core operates on a cost recovery basis. Prior to access, users need to supply a valid account that will be charged at the end of the month of access. Sometimes it is more expedient or necessary to use other available Cytometry and Microscopy cores. We fully support this and cooperate with facilities for cytometry - Center for AIDS Research, Infectious Diseases, LRI Flow Cytometry Core, and microscopy - CWRU SOM Neurosciences and the Lerner Research Institute.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Molecular Biotechnology (MBT) Core offers consultation and services in the areas of customized peptide synthesis, peptide modification, purification and quality analysis. The Core also offers CD Spectroscopy and biomolecular interaction analysis and equilibrium and kinetic measurements using Biacore 3000 and Isothermal Titration Calorimetry. The MBT core provides a wide range of high quality services in areas of peptide synthesis, surface plasmon resonance and other biophysical technologies. The core has a microwave based peptide synthesizer (Liberty, CEM Inc.) and an Omega 396 multiple peptide synthesizer. Biomolecular interactions are quantified using Biacore 3000, while isothermal titration calometer (iTC 200) is used for measuring the thermodynamic parameters (kinetics. enthalpy, entropy and number of binding sites)of biomolecular interactions. Jasco 815 CD spectrophotometer is capable for analysis of secondary structure of proteins in solution and protein folding and confirmation changes. The Core also oversees the Storm 820 phosphor imager. Peptides Synthesis Surface Plasmon Resonance Isothermal Titration Calorimetry Circular Dichroism Spectroscopy Phosphor Imaging

9500 Euclid Avenue Cleveland, Ohio 44195The Molecular Biotechnology (MBT) Core offers consultation and services in the areas of customized peptide synthesis, peptide modification, purification and quality analysis. The Core also offers CD Spectroscopy and biomolecular interaction analysis and equilibrium and kinetic measurements using Biacore 3000 and Isothermal Titration Calorimetry. The MBT core provides a wide range of high quality services in areas of peptide synthesis, surface plasmon resonance and other biophysical technologies. The core has a microwave based peptide synthesizer (Liberty, CEM Inc.) and an Omega 396 multiple peptide synthesizer. Biomolecular interactions are quantified using Biacore 3000, while isothermal titration calometer (iTC 200) is used for measuring the thermodynamic parameters (kinetics. enthalpy, entropy and number of binding sites)of biomolecular interactions. Jasco 815 CD spectrophotometer is capable for analysis of secondary structure of proteins in solution and protein folding and confirmation changes. The Core also oversees the Storm 820 phosphor imager. Peptides Synthesis Surface Plasmon Resonance Isothermal Titration Calorimetry Circular Dichroism Spectroscopy Phosphor Imaging

10900 Euclid Avenue Cleveland, OH, 44106 United StatesThe Behavioral Measurement Core Facility (BMC) offers a full range of services to assist investigators interested in the use of rigorous, behavioral research methods for clinical, prevention and other cancer-related research. The BMC works with researchers at all stages of the research process to identify appropriate research strategies, implement behavioral data collection using custom-designed measurement tools or adapting existing measures of behavioral constructs to fit each investigator’s research question and unique hypotheses.

10900 Euclid Ave., Cleveland, Ohio 44106The Behavioral Measurement Core Facility (BMC) offers a full range of services to assist investigators interested in the use of rigorous, behavioral research methods for clinical, prevention and other cancer-related research. The BMC works with researchers at all stages of the research process to identify appropriate research strategies, implement behavioral data collection using custom-designed measurement tools or adapting existing measures of behavioral constructs to fit each investigator’s research question and unique hypotheses.

3333 Burnet Ave. Cincinnati, OH 45229-3039 USACincinnati Children's Hospital Medical Center Mouse Cytogenetics Core offers research investigators support for mouse classic karyotyping and molecular cytogenetic studies.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Vector Production Facility and Vector Core manufacturing of viral vectors in support of early phase clinical trials.

3333 Burnet Avenue Cincinnati, OH 45229-3039 USACincinnati Children's Translational Trials Development and Support Laboratory (TTDSL) offers assays for cellular and molecular testing in application of clinical and non clinical studies.

Cleveland, OH, 44106 United StatesThis CLIA - approved core provides small molecule analytical and pharmacokinetic data reduction services for non-cancer related clinical trials and pre-clinical studies. The core houses high performance liquid chromatographs with spectrophotometric, fluorimetric, and mass spectrometric detectors. This equipment facilitates selective, sensitive, and accurate quantitation of small molecules such as drugs, drug metabolites, and metabolic intermediates (done in conjunction with the Center for Inherited Disorders of Energy Metabolism at UHHC). The staff modifies methods from existing literature or develops new analytical methodology as required. They provide advice concerning optimal sampling schedules and collection - time sample treatment for clinical pharmacokinetics trials, and they carry out rigorous pharmacokinetics analysis and modeling of data from those trials. The core also can assist investigators by providing basic feasibility data for use in grant proposal preparation.

Cleveland, Ohio 44106This CLIA - approved core provides small molecule analytical and pharmacokinetic data reduction services for non-cancer related clinical trials and pre-clinical studies. The core houses high performance liquid chromatographs with spectrophotometric, fluorimetric, and mass spectrometric detectors. This equipment facilitates selective, sensitive, and accurate quantitation of small molecules such as drugs, drug metabolites, and metabolic intermediates (done in conjunction with the Center for Inherited Disorders of Energy Metabolism at UHHC). The staff modifies methods from existing literature or develops new analytical methodology as required. They provide advice concerning optimal sampling schedules and collection - time sample treatment for clinical pharmacokinetics trials, and they carry out rigorous pharmacokinetics analysis and modeling of data from those trials. The core also can assist investigators by providing basic feasibility data for use in grant proposal preparation.

Cleveland, OH, 44106 United StatesThe Immune Function Core Facility is dedicated to providing researchers with the necessary tools to successfully perform immunoassays. The Core provides access to equipment (flow cytometers, automated magnetic bead cell sorter, infrared imager and ELISA plate reader & washer) and technical support. The Cores services are available not only for CFAR members, but also for the rest of the CWRU research community. The Immune Function Core strives to make immunology research more efficient and affordable. Investigators may obtain protocols as well as access equipment to run Cytokine ELISA's, Elispot assays, cell selections/depletions, and flow based assays. Additionally, the Core technician can perform immune assays for investigators. These include ELISA, Elispot, cell selections/depletions and flow cytometry.

Cleveland, Ohio 44106The Immune Function Core Facility is dedicated to providing researchers with the necessary tools to successfully perform immunoassays. The Core provides access to equipment (flow cytometers, automated magnetic bead cell sorter, infrared imager and ELISA plate reader & washer) and technical support. The Cores services are available not only for CFAR members, but also for the rest of the CWRU research community. The Immune Function Core strives to make immunology research more efficient and affordable. Investigators may obtain protocols as well as access equipment to run Cytokine ELISA's, Elispot assays, cell selections/depletions, and flow based assays. Additionally, the Core technician can perform immune assays for investigators. These include ELISA, Elispot, cell selections/depletions and flow cytometry.

11901 Mosteller Road Cincinnati, OH 45241

10900 Euclid Avenue Cleveland, OH, 44106 United StatesThe mission of the Biostatistics & Bioinfomatics Core Facility (BBCF) is to provide and coordinate statistical, bioinformatics, and clinical informatics research support to Case CCC members in the design, planning, conduct, analysis, and reporting of research studies. Core members also play a key role in protocol review and study monitoring in the Case CCC. Services Study Design and Protocol Development Review of Cancer Center Protocols Data and Study Monitoring Biostatistical and Bioinformatics Analysis and Reporting Database Development and Management Participation in Educational and Training Activities in the Case CCC

10900 Euclid Ave., Cleveland, Ohio 44106The mission of the Biostatistics & Bioinfomatics Core Facility (BBCF) is to provide and coordinate statistical, bioinformatics, and clinical informatics research support to Case CCC members in the design, planning, conduct, analysis, and reporting of research studies. Core members also play a key role in protocol review and study monitoring in the Case CCC. Services Study Design and Protocol Development Review of Cancer Center Protocols Data and Study Monitoring Biostatistical and Bioinformatics Analysis and Reporting Database Development and Management Participation in Educational and Training Activities in the Case CCC

9500 Euclid Avenue Cleveland, Ohio 44195The Laboratory Diagnostic Core offers investigators a large menu of automated clinical chemistry assays, elisa based testing, hematology and phlebotomy services. The LDC has maintained accreditation with the College of American Pathologists and CLIA for more than ten years. The Core has been a CDC Lipid Standardization Laboratory since 2001. The laboratory test menu includes assays for both human and animal samples. The Laboratory Diagnostic Core (LDC) has maintained CAP (College of AmericanPathologists) and CLIA (Clinical Laboratory Improvement Act) accreditations since 2001 and has maintained the required standards for the past 10 years. It is also a CDC Lipid Standardization lab. This program ensures that lipid measurements are accurate and comparable, particularly for clinical trials. The Laboratory Diagnostic Core offers investigators an extensive menu of automated clinical chemistry, immunology and hematology assays (over 200). Tests range from commercially available FDA approved methods to research grade ELISA’s.

974 Checkrein Av Columbus, OH 43229 USACelartia offers their proprietary cell culture system and high technology instruments to support biological research.

10900 Euclid Avenue Cleveland, OH, 44106 United States

10900 Euclid Ave., Cleveland, Ohio 44106

3333 Burnet Ave. MLC 5033 Cincinnati, OH 45229-3039 USACincinnati Children's Hospital Medical Center Imaging Research Center provides investigators at Cincinnati Children’s, the University of Cincinnati and other research institutions access to advanced analytical imaging and image post-processing methods.

3130 Highland Avenue Floor 2 Cincinnati, OH 45219Cardio Energetics Inc is a Marketing and Advertising company located in 3130 Highland Ave, Cincinnati, Ohio, United States.

9500 Euclid Avenue Cleveland, Ohio 44195The Flow Cytometry Core provides investigators with a resource for analytical and preparative studies of cells using flow cytometry. The Core offers FACS acquisition and analysis, cell sorting, and consultation for experimental design, interpretation and troubleshooting. Applications include immunophenotyping, intracellular staining, molecular and cellular probes such as Ca flux and GFP, CBA (Cytometric Bead Array), DNA cell cycle, TUNEL and Annexin V for apoptosis, sterile sorting for cloning and more. Both the LSRFortessa and Aria II have a green 561nm laser, which is optimal for detection of "mFruit" fluorescent proteins.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Animal Behavior Core offers behavioral phenotyping of rodent models.

Cleveland, OH, 44106 United StatesThe Light Microscopy Imaging Core Facilities on the Case Western campus are shared resources that offer a wide range of imaging services to the research community. Our facilities are committed to enhancing and expanding collaborative capabilities of research in northern Ohio. Imaging techniques available through the cores include: standard transmitted light microscopy: brightfield darkfield phase contrast interference contrast polarization fluorescence live-cell long term imaging confocal multi-photon deconvolution TIRF super resolution slide scanning (brightfield and fluorescence) Our range of instruments allows for most types of modern imaging techniques from basic widefield imaging to very high spatial and temporal resolution imaging of fixed and live cells, tissues or small organisms. Image processing and analysis capabilities include image: quantification co-localization analysis deconvolution 3D reconstruction stereology Those microscopes are often used for analyzing human and animal cells under pathological conditions such as cancer, neuronal degeneration, and metabolic disorders. By allowing high-resolution and dynamic analysis of biological tissues under pathological status, this core supports translational research. An additional application includes optimization of cell-based fluorescence assays for drug screening. Moreover, the slide scanning capability allows completely automated, high-throughput analysis of fixed human pathology specimens while the image processing capabilities allow unbiased comparison of samples from healthy and diseased tissues.

Cleveland, Ohio 44106The Light Microscopy Imaging Core Facilities on the Case Western campus are shared resources that offer a wide range of imaging services to the research community. Our facilities are committed to enhancing and expanding collaborative capabilities of research in northern Ohio. Imaging techniques available through the cores include: standard transmitted light microscopy: brightfield darkfield phase contrast interference contrast polarization fluorescence live-cell long term imaging confocal multi-photon deconvolution TIRF super resolution slide scanning (brightfield and fluorescence) Our range of instruments allows for most types of modern imaging techniques from basic widefield imaging to very high spatial and temporal resolution imaging of fixed and live cells, tissues or small organisms. Image processing and analysis capabilities include image: quantification co-localization analysis deconvolution 3D reconstruction stereology Those microscopes are often used for analyzing human and animal cells under pathological conditions such as cancer, neuronal degeneration, and metabolic disorders. By allowing high-resolution and dynamic analysis of biological tissues under pathological status, this core supports translational research. An additional application includes optimization of cell-based fluorescence assays for drug screening. Moreover, the slide scanning capability allows completely automated, high-throughput analysis of fixed human pathology specimens while the image processing capabilities allow unbiased comparison of samples from healthy and diseased tissues.

2103 Cornell Rd. 5537 WRB Cleveland, OH 44106-7288 USACase Western Reserve University Department of Pathology focuses on research in neuropathology and immunology with facilities in tissue procurement and histology.

Innovation Centre 2001 Polaris Parkway Columbus, OH 43240The Human Tissue Resource Network (HTRN) provides a variety of services to researchers and clinicians at The Ohio State University Wexner Medical Center as well as basic and translational outreach programs throughout the United States and Canada. Services include biospecimen and biofluid procurement and processing, biobanking, histology, tissue microarray (TMA), immunohistochemistry (IHC), fluorescent in situ hybridization (FISH), chromogenic in situ hybridization (CISH) and molecular testing, and virtual microscopy and digital image analysis. Three federally funded research programs are supported by the HTRN including the Collaborative (AKA Cooperative) Human Tissue Network (CHTN), the ALLIANCE for Clinical Trials and Oncology, and the OSU Comprehensive Cancer Center Total Cancer Care Program (TCCP) accompanied by corporate funding and department research programs. HTRN sections that help to support these programs include the Pathology Core Facility (PCF), Tissue Archive Service (TAS), Research Tissue Procurement Service (RTPS), Specialty Labs including digital imaging and laser capture microscopy, and biorepository services.

2109 Adelbert Road Cleveland, OH, 44106 United StatesThe Clinical Services Core (CSC) is a central resource designed to support each step in the development, conduct, and analysis of all human subject research projects originated from or supported by the Case CFAR. The Core has maintained and expanded a comprehensive and accessible Patient Care and Research Database and linked specimen repository that both facilitates clinical management and serves as a robust resource for research activities. The core provides researchers with access to patients pre-selected for interest and identified as eligible, through the Patient Care and Research Database, to participate in HIV clinical trials or other research studies. It maintains and provides access to a newly established database of over 800 HIV-negative volunteers in the Cleveland area who are interested in participating in HIV research. Assists CFAR researchers in planning and designing studies that use the PCRD and the specimen repository by helping investigators formulate research questions that take full advantage of the data and specimens available through the Core. The Core also coordinates the exchange of clinical and laboratory data with other institutions participating in collaborative projects designed to conduct research on HIV observational data. The Case CFAR is a founding member of two such collaborations, the CFAR Network of Integrated Clinical Systems (CNICS) and the North American AIDS Cohort Collaboration on Research and Design (NAACCORD). Lastly, the Core provides biostatistical and epidemiologic support and advice to Case CFAR investigators, and provides training and faculty development in epidemiology and biostatistics.

Room W200, Wood Building 2109 Adelbert Rd. Cleveland, Ohio 44106The Clinical Services Core (CSC) is a central resource designed to support each step in the development, conduct, and analysis of all human subject research projects originated from or supported by the Case CFAR. The Core has maintained and expanded a comprehensive and accessible Patient Care and Research Database and linked specimen repository that both facilitates clinical management and serves as a robust resource for research activities. The core provides researchers with access to patients pre-selected for interest and identified as eligible, through the Patient Care and Research Database, to participate in HIV clinical trials or other research studies. It maintains and provides access to a newly established database of over 800 HIV-negative volunteers in the Cleveland area who are interested in participating in HIV research. Assists CFAR researchers in planning and designing studies that use the PCRD and the specimen repository by helping investigators formulate research questions that take full advantage of the data and specimens available through the Core. The Core also coordinates the exchange of clinical and laboratory data with other institutions participating in collaborative projects designed to conduct research on HIV observational data. The Case CFAR is a founding member of two such collaborations, the CFAR Network of Integrated Clinical Systems (CNICS) and the North American AIDS Cohort Collaboration on Research and Design (NAACCORD). Lastly, the Core provides biostatistical and epidemiologic support and advice to Case CFAR investigators, and provides training and faculty development in epidemiology and biostatistics.

10900 Euclid Avenue Cleveland, OH, 44106 United StatesThe Tissue Resources Core facility is a specialized unit of the Human Tissue Procurement Facility (HTPF) that supports Cancer Center member researchers by acquiring, preserving, and distributing high quality human tissues and providing priority histology, immunohistochemistry, tissue microarray, and laser capture microdissection services for both human and animal tissues. Services are open to all Cancer Center members on an equal basis. Free parking is provided to members picking up samples who work off the CWRU/University Hospitals campus. Samples are for research purposes only and may not be used for clinical diagnosis or implantation into humans. Clinical information relating to the samples and donors are collected and maintained in a secure database. Samples and data are de-identified or de-linked before release to the researcher unless he/she has specific IRB approval to gain access to this information. Please note: Researchers must complete a formal application and have an IRB approval or exemption for the study to access human tissue from the Core.

10900 Euclid Ave., Cleveland, Ohio 44106The Tissue Resources Core facility is a specialized unit of the Human Tissue Procurement Facility (HTPF) that supports Cancer Center member researchers by acquiring, preserving, and distributing high quality human tissues and providing priority histology, immunohistochemistry, tissue microarray, and laser capture microdissection services for both human and animal tissues. Services are open to all Cancer Center members on an equal basis. Free parking is provided to members picking up samples who work off the CWRU/University Hospitals campus. Samples are for research purposes only and may not be used for clinical diagnosis or implantation into humans. Clinical information relating to the samples and donors are collected and maintained in a secure database. Samples and data are de-identified or de-linked before release to the researcher unless he/she has specific IRB approval to gain access to this information. Please note: Researchers must complete a formal application and have an IRB approval or exemption for the study to access human tissue from the Core.

7100 Euclid Avenue Cleveland, OH, 44103 United StatesThe Virology, Next Generation Sequencing and Imaging Core supports research on HIV and associated pathogens. The Core provides services in support of virology research that include creating and producing recombinant HIV and lentiviral vector stocks, support of shRNA library screens, high throughput, next-generation DNA sequencing (NGS) and access to biocontained, high resolution fluorescence microscopy.

7100 Euclid Ave., Suite 190, Cleveland, OHThe Virology, Next Generation Sequencing and Imaging Core supports research on HIV and associated pathogens. The Core provides services in support of virology research that include creating and producing recombinant HIV and lentiviral vector stocks, support of shRNA library screens, high throughput, next-generation DNA sequencing (NGS) and access to biocontained, high resolution fluorescence microscopy.

3333 Burnet Ave, ML-7013 Cincinnati, OH 45229-3039 USACincinnati Children's Hospital Medical Center Cell Processing Core and Cell Manipulations Laboratory offers a variety of human hematopoietic cells or other products to investigators for their research programs.

P.O. Box 1123 Dayton, Ohio 45401 USAChemineer is a supplier of mixing solutions and products to customers worldwide.

9500 Euclid Avenue Cleveland, Ohio 44195The Lerner Research Institute Computing Services group provides support for the desktop, server, and network-computing infrastructure of the Institute. The combined supported user base is greater than 1,000. Platforms supported include Windows 9x/NT/2000/XP, Windows Server 2000 and 2003, Macintosh OS 7 to 9 and Macintosh OS X, and the Unix variants SGI Irix, Sun Solaris, and Linux. The group provides support for shared network disk space and backup, various Internet communication and collaboration protocols, and application and print servers. It maintains domain name services for the /17 RFC 1918 IP allocation assigned to the Lerner Research Institute by the Cleveland Clinic Information Technology Division and administers the lerner.ad.cchs.net subdomain of Cleveland Clinic's Active Directory forest. The Desktop group provides custom support of the scientific computing workstations across the Macintosh and Windows platforms. The Windows Server team specializes in supporting the Windows Server environment, including domain controller, file, and print, and application services, and Windows and Unix backup. In cooperation with Unix and Desktop support, the Windows Server Team works to provide a collaborative cross-platform computing environment. Unix workstations and servers currently participate in a unified computing structure supported by a dedicated Unix administration team.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USAA service of the Clinical Translational Research Center’s Bionutrition Core, the Cincinnati Center for Nutrition Research and Analysis (CCNRA) offers data collection, coding and nutrition data analysis for both pediatric and adult clinical research studies.

1265 Ridge Road Ste. A Hinckley, OH 44233 USAClinical Research Management provides clinical research associates, clinical support, project management, and drug storage.

9500 Euclid Avenue Cleveland, Ohio 44195Medical Device Solutions or MDS was created at Cleveland Clinic to act as a bridge between clinical ideas and licensed medical devices. Our experience in medical device development can quickly and efficiently transform promising new device ideas into functional prototypes. For more information about MDS view MDS Brochure. Five technical specialty cores and a regional Nitinol Center form the integrated MDS team as listed below: BioRobotics and Mechanical Testing Core (BRMTC) is a fee-for-service facility providing a center of excellence for biomechanical testing of biological structures and biomaterials. BRMTC employ world class facilities to allow investigators to conduct high quality research of the mechanical properties of existing biological structures and constructs, as well as to quantify the potential for new technologies and clinical advancements. The Electronics facility is an electronic design, fabrication and repair laboratory that specializes in custom electronics, electro-mechanical systems, transducers and optics for biomedical applications. We have extensive experience in all aspects of medical research instrumentation. The Engineering & Design group consists of mechanical and biomedical engineers who focus on research and development related to new medical devices. This team uses state-of-the-art computer-aided design software, finiteelement analysis, rapid prototyping and computational fluid dynamic modeling when evaluating new medical devices. The Mechanical Prototype staff is highly skilled in a variety of fabrication, customization and repair services for mechanical devices and equipment. We are proficient in precision machining of metals and plastics, welding of structural and exotic metals, instrument refurbishing and mechanical repair. The Polymer Laboratory supports research and product development efforts where polymeric and biologic materials are required. The laboratory uses both synthetic and natural polymeric materials such as: Polyurethane Polyolefin Silicone Epoxies PVC & Natural Rubber A new regional Nitinol Commercialization Center is now a part of the MDS team. Nitinol is a relatively new alloy that is being incorporated into medical and commercial applications because of its extraordinary shape memory and superelastic properties. Nitinol’s medical device capabilities include: Quick lead times Able to build prototypes in small quantities and at a low price Heat Treatment, Lasercutting and Shapesetting advance features

11901 Mosteller Road Cincinnati, OH 45241CSZ Testing offers stability testing and accelerated aging services.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Lenti-shRNA Library Core gives investigators at Cincinnati Children’s and UC access to cutting-edge high-throughput screening (HTS), allowing for non-biased discovery of novel genes that affect biologic pathways of interest.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe objectives of the Polymer Core are to support research and product development efforts where polymeric and biologic materials are required. The Polymer Lab provides plastic, rubber, and biomaterial related services, including initial medical device design, prototyping, and evaluation, as well as routine technical service. Medical Device Design and Evaluation The Polymer Lab covers all areas of medical device development starting with the initial brainstorming session, device design, prototyping, and device testing including in vitro and in vivo. This lab has been intimately involved in the fabrication of the artificial heart and the ventricle assist device at Cleveland Clinic for the past 25 years. We also work on a wide variety of balloon, valve, catheter, cannula, stent, and prosthetic-related devices.

9500 Euclid Avenue Cleveland, Ohio 44195The objectives of the Polymer Core are to support research and product development efforts where polymeric and biologic materials are required. The Polymer Lab provides plastic, rubber, and biomaterial related services, including initial medical device design, prototyping, and evaluation, as well as routine technical service. Medical Device Design and Evaluation The Polymer Lab covers all areas of medical device development starting with the initial brainstorming session, device design, prototyping, and device testing including in vitro and in vivo. This lab has been intimately involved in the fabrication of the artificial heart and the ventricle assist device at Cleveland Clinic for the past 25 years. We also work on a wide variety of balloon, valve, catheter, cannula, stent, and prosthetic-related devices.

Cincinnati, OH United StatesCTI Clinical Trial and Consulting Services offers drug development, regulatory consulting, healthcare communications, and medical education services.

10123 Alliance Road Cincinnati, OH 45242 USACTI Clinical Trial and Consulting Services offers drug development, regulatory consulting, healthcare communications, and medical education services.

Cleveland, Ohio 44106The Clemson University Greenhouse Complex is a support facility for basic and applied plant research housed in the Biosystems Research Complex. The facility contains over 40,000 square feet of greenhouse space and a 16,000 square-foot headhouse. The greenhouse facility is comprised of two ranges of greenhouses each aligned along a central corridor. Together the ranges contain 24 greenhouse 4 bench zones measuring 36’ x 35', 8 greenhouse single bench zones measuring 12' x 35’, and 4 covered growing areas. The headhouse contains all of the support facilities for the greenhouse including a preparation area, demonstrGreenhouse Plantsation room, temperature-controlled storage rooms, general laboratory, level 3 containment laboratory, seven growth rooms, reach-in growth chambers, shop, pesticide and fertilizer storage and mixing areas, autoclaves, and emergency utility equipment.

Cleveland, OH United StatesCase Western Reserve University Department of Dermatology focuses on research for skin diseases.

11100 Euclid Avenue Lakeside 3500 Cleveland, OH 44106 USACase Western Reserve University Department of Dermatology focuses on research for skin diseases.

9500 Euclid Avenue Cleveland, Ohio 44195Immunohistochemistry (IHC) allows investigators to visualize the expression levels and distribution of specific cell or tissue antigens. Due to the variability among antibodies and techniques, IHC requires significant knowledge of basic histology, available immunological reagents, antigen retrieval techniques and immunohistochemical procedures. It can be time consuming and may require considerable titration and optimization of antibodies before research samples can be stained. It may also require experimentation with different antigen retrieval methods for paraffin tissues as well as experimentation with different fixatives for fresh frozen tissues. Capabilities overview Expert advice in the planning and evaluation of IHC experiments Immunohistochemical staining Immunofluorescence staining

20600 Sheldon Road Brook Park, Ohio 44142 USACetek provides environmental and energy-enhancing services & solutions.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Comprehensive Mouse and Cancer Core offers a number of services for researchers exploring cancer systems through animal models.

10900 Euclid Avenue Cleveland, OH, 44106 United StatesRadiopharmaceuticals are drugs that are labeled with a radioisotope and used in the field of nuclear medicine as tracers in the diagnosis and treatment of many diseases. Over the past decades, cutting-edge nuclear imaging techniques such as position emission tomography (PET) and single photon emission tomography (SPECT) have been developed and integrated into routine clinical practice. These advanced techniques are used in combination of trace amount of radiopharmaceuticals to image or visualize the body functions and physiologic processes at the molecular level. Unlike conventional studies in the field of radiology, nuclear imaging studies such as PET and SPECT generally depend on administration of a radiotracer or radiopharmaceutical that is specific for the targets to be imaged. As a result, a variety of radiopharmaceuticals have been developed. Among the radiopharmaceuticals that are widely used, only a few are made commercially available for PET imaging studies. Most of the radiopharmaceuticals, however, need to be custom-synthesized using an on site cyclotron. In fact, due to the short half-life of some radionuclides such as C-11 (t1/2 20 min), many radiolabelled radiopharmaceuticals must be synthesized immediately before imaging studies. For this reason, a state-of-the-art PET radiopharmaceutical core facility was established in 2006 to provide radiotracers to the research community for nuclear imaging research at Case and affiliated institutions. The facility is designed to provide critical support to biomedical research communities in response to the molecular imaging needs in their ongoing projects and also to provide guidance on forward-looking and cutting edge research programs.

Bolwell Building, Room SB109 10900 Euclid Ave., Cleveland, Ohio 44106Radiopharmaceuticals are drugs that are labeled with a radioisotope and used in the field of nuclear medicine as tracers in the diagnosis and treatment of many diseases. Over the past decades, cutting-edge nuclear imaging techniques such as position emission tomography (PET) and single photon emission tomography (SPECT) have been developed and integrated into routine clinical practice. These advanced techniques are used in combination of trace amount of radiopharmaceuticals to image or visualize the body functions and physiologic processes at the molecular level. Unlike conventional studies in the field of radiology, nuclear imaging studies such as PET and SPECT generally depend on administration of a radiotracer or radiopharmaceutical that is specific for the targets to be imaged. As a result, a variety of radiopharmaceuticals have been developed. Among the radiopharmaceuticals that are widely used, only a few are made commercially available for PET imaging studies. Most of the radiopharmaceuticals, however, need to be custom-synthesized using an on site cyclotron. In fact, due to the short half-life of some radionuclides such as C-11 (t1/2 20 min), many radiolabelled radiopharmaceuticals must be synthesized immediately before imaging studies. For this reason, a state-of-the-art PET radiopharmaceutical core facility was established in 2006 to provide radiotracers to the research community for nuclear imaging research at Case and affiliated institutions. The facility is designed to provide critical support to biomedical research communities in response to the molecular imaging needs in their ongoing projects and also to provide guidance on forward-looking and cutting edge research programs.

Research Core Services Cleveland Clinic, Mail Code NB21 9500 Euclid Avenue Cleveland, Ohio 44195The Glassware Core provides glassware washing and sterilization of all types of glassware and pipettes. The facility maintains a stock glassware in a common storage area. Glassware personnel collect glassware from laboratories daily and cabinets are replenished regularly. Autoclaving of materials is offered on a daily basis. The core can accommodate any special requests. The Glassware core maintains a stock of all types of sterile laboratory glassware and pipettes in the common storage area. This facility provides glass washing and sterilization to all investigators within the Lerner Research Institute.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Pathology Research Core provides technical support for routine morphology based techniques including tissue processing and embedding, routine and special histochemical staining, immunohistochemistry, in situ hybridization, and electron microscopy.

Cleveland, OH, 44106 United StatesThe Population Health and Outcomes Research Core uses population-based databases (e.g., Medicare and Medicaid administrative databases, Vital Records, the Surveillance, Epidemiology, and End Results (SEER) data) which represent rich sources of data, from “real world” settings, and offer an unparalleled opportunity to examine patterns of health care use, morbidity, mortality, and other process and outcomes measures in various subgroups of the population. In particular, where multiple treatment alternatives are available for a specific medical condition, these databases offer a unique opportunity to conduct comparative effectiveness research (CER) to identify the most effective treatment modality. The Population Health and Outcomes Research Core (PHORC) integrates and mobilizes a vast archive of population-based databases and provides expertise in working with them to conduct outcomes and disparities research. This includes a large computing capacity to create an infrastructure to respond to researchers’ needs in CER. This Laboratory collaborates with researchers at or outside of CWRU.

Cleveland, Ohio 44106The Population Health and Outcomes Research Core uses population-based databases (e.g., Medicare and Medicaid administrative databases, Vital Records, the Surveillance, Epidemiology, and End Results (SEER) data) which represent rich sources of data, from “real world” settings, and offer an unparalleled opportunity to examine patterns of health care use, morbidity, mortality, and other process and outcomes measures in various subgroups of the population. In particular, where multiple treatment alternatives are available for a specific medical condition, these databases offer a unique opportunity to conduct comparative effectiveness research (CER) to identify the most effective treatment modality. The Population Health and Outcomes Research Core (PHORC) integrates and mobilizes a vast archive of population-based databases and provides expertise in working with them to conduct outcomes and disparities research. This includes a large computing capacity to create an infrastructure to respond to researchers’ needs in CER. This Laboratory collaborates with researchers at or outside of CWRU.

2121 Euclid Avenue Cleveland, OH, 44115 United States

2121 Euclid Avenue, Cleveland, OH 44115-2214

11100 Euclid Avenue Lakeside 3500 Cleveland, OH 44106 USACase Western Reserve University Department of Otolaryngology focuses on research areas of molecular otology, hearing loss, hair regeneration, auditory proteomics, and tissue engineering.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Genetic Variation and Gene Discovery Core offers next generation DNA sequencing, conventional (Sanger) sequencing, whole genome genotyping, genome methylation analysis, and DNA extraction services.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center BioBank Core provides access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USAThe PSCF is dedicated to providing high quality, well characterized, and reliably archived human embryonic and induced pluripotent stem cells for distribution to researchers.

10900 Euclid Avenue Cleveland, OH, 44106 United StatesThe Gene Expression & Genotyping Facility (GEGF) facilitates implementation of high throughput genetic technologies for the research conducted by members of the Case community.

10900 Euclid Ave., Cleveland, Ohio 44106The Gene Expression & Genotyping Facility (GEGF) facilitates implementation of high throughput genetic technologies for the research conducted by members of the Case community.

9500 Euclid Avenue Cleveland, Ohio 44195BioRobotics and Mechanical Testing Core (BRMTC) is a center of excellence for biomechanical testing of biological structures and biomaterials. Our Mission is to employ world class facilities to allow investigators to conduct high quality research of the mechanical properties of existing biological structures and constructs, as well as to quantify the potential for new technologies and clinical advancements.

Cincinnati, OH United StatesWe aim to promote world-class biomedical research by ensuring availability of the highest quality biospecimens to meet researchers’ needs. We provide access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research. These services are available to researchers at Cincinnati Children’s Hospital Medical Center, surrounding academic centers and beyond. We are also home to the Better Outcomes for Children (BofC) biorepository. BofC is an institution-wide initiative to collect and store leftover clinical samples for research use. The Cincinnati Biobank offers sample collection, processing, storage and distribution services for investigator developed sample collections. We perform specialized banking and processing, as well as bulk processing and storage. Cincinnati Biobank personnel have experience planning and executing sample collection protocols based on the latest biospecimen research and evidence-based methodology.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Digital Imaging Microscopy Core is part of the LRI Imaging Core. It is home to a wide range of high quality microscope imaging instruments — from excellent basic equipment to the most advanced imaging technologies. Experienced staff members are ready to help with the planning of imaging experiments, use of the microscopes, and the processing and analysis of data. In addition, the Core provides several computer workstations with imaging software.

9500 Euclid Avenue Cleveland, Ohio 44195The Digital Imaging Microscopy Core is part of the LRI Imaging Core. It is home to a wide range of high quality microscope imaging instruments — from excellent basic equipment to the most advanced imaging technologies. Experienced staff members are ready to help with the planning of imaging experiments, use of the microscopes, and the processing and analysis of data. In addition, the Core provides several computer workstations with imaging software.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Lerner Research Institute's Proteomics and Metabolomics Laboratory uses advanced mass spectrometry methods for the sequencing of proteins and the analysis of small molecules. The goal of the core is to help investigators with the qualitative and quantitative characterization of proteins and small molecules in biological matrices such as plasma/serum, urine, tissues, cell lines, along with other biological materials. The Proteomics applications include the identification of protein from gel bands or in-solution, identification and quantitation of post-translational modifications, and the global quantitative analysis of proteomes. The Metabolomics applications include both targeted and untargeted quantitative analysis of metabolites.

9500 Euclid Avenue Cleveland, Ohio 44195The Lerner Research Institute's Proteomics and Metabolomics Laboratory uses advanced mass spectrometry methods for the sequencing of proteins and the analysis of small molecules. The goal of the core is to help investigators with the qualitative and quantitative characterization of proteins and small molecules in biological matrices such as plasma/serum, urine, tissues, cell lines, along with other biological materials. The Proteomics applications include the identification of protein from gel bands or in-solution, identification and quantitation of post-translational modifications, and the global quantitative analysis of proteomes. The Metabolomics applications include both targeted and untargeted quantitative analysis of metabolites.

3200 Vine Street Cincinnati, OH, 45220 United StatesMission Honor America's Veterans by providing exceptional health care that improves their health and well-being. Vision We will continue to be the benchmark of excellence and value in health care and benefits by providing exemplary services that are both patient centered and evidence based. This care will be delivered by engaged, collaborative teams in an integrated environment that supports learning, discovery and continuous improvement. It will emphasize prevention and population health and contribute to the nation's well-being through education, research and service in National emergencies. Highlights Cincinnati VAMC consists of 2 divisions located in Cincinnati, Ohio and Fort Thomas, Kentucky. Provides services to 17 counties in Ohio, Kentucky, and Indiana. Cincinnati VAMC has an active affiliation with the University of Cincinnati College of Medicine. Referral site for neurosurgery. PTSD Residential Programs for Men & Women. PTSD/Traumatic Brain Injury Residential Program. Iraq/Afghanistan Clinic Veterans Mobile Health Unit

3200 Vine Street Cincinnati, OH 45220Mission Honor America's Veterans by providing exceptional health care that improves their health and well-being. Vision We will continue to be the benchmark of excellence and value in health care and benefits by providing exemplary services that are both patient centered and evidence based. This care will be delivered by engaged, collaborative teams in an integrated environment that supports learning, discovery and continuous improvement. It will emphasize prevention and population health and contribute to the nation's well-being through education, research and service in National emergencies. Highlights Cincinnati VAMC consists of 2 divisions located in Cincinnati, Ohio and Fort Thomas, Kentucky. Provides services to 17 counties in Ohio, Kentucky, and Indiana. Cincinnati VAMC has an active affiliation with the University of Cincinnati College of Medicine. Referral site for neurosurgery. PTSD Residential Programs for Men & Women. PTSD/Traumatic Brain Injury Residential Program. Iraq/Afghanistan Clinic Veterans Mobile Health Unit

38259 Kingston Drive North Ridgeville, OH, 44039 United Statescosmetictranslation.com offers unique professional translation services exclusively to the cosmetic industry. Our collaborative team approach combines the skills of outstanding, certified translators with an in-depth knowledge of cosmetics – products, advertising, marketing, sales and technology. The result is superbly accurate translations that convey the true spirit of the original cosmetic copy. Our cosmetic translation specialties include . . . • Product Labels • Web Sites • Advertising Copy • Scientific Papers • Sales Literature • Patents • Brochures & Catalogs • Regulatory Documents Knowledge of language alone won’t do the job: We also speak cosmetics! Our translators are highly educated, dedicated professionals with a love for the nuance of language and a commitment to excellence. In addition, they are backed by a thorough understanding of cosmetic products including skincare, haircare, deodorant, fragrance, shaving and pigmented products. We have more than 40 years of experience in cosmetics in areas ranging from cosmetic product formulation and regulatory requirements to the creation of marketing strategies and advertising copy…and apply this knowledge to every cosmetic translation we perform. High quality, fair rates and responsive service. Our simple but ambitious goal is to be accepted as a member of the team by each of our clients.

2103 Cornell Road Cleveland, OH, 44106 United StatesThe Computational Biology Core is a collaborative and/or fee for service facility within the ICB aimed at providing computational and analytical support for a variety of research questions. Modern high-throughput experiments generate massive amounts of data that must be processed and checked extensively for quality control. The ICB Computational Biology Core supports these experiments with standardized and custom pipelines for data processing and analysis of next-generation sequencing data.

Wolstein Research Building 2103 Cornell Road, Suite 2533 Cleveland, Ohio 44106-7295The Computational Biology Core is a collaborative and/or fee for service facility within the ICB aimed at providing computational and analytical support for a variety of research questions. Modern high-throughput experiments generate massive amounts of data that must be processed and checked extensively for quality control. The ICB Computational Biology Core supports these experiments with standardized and custom pipelines for data processing and analysis of next-generation sequencing data.

Cleveland, OH, 44106 United StatesLocated on the 8th floor of the BRB, The Bioanalyte Core utilizes quantitative and qualitative assays to measure bioanalytes such as cytokines, lipid metabolites, inflammatory markers. The analysis includes measuring soluble production of the bioanalyte, how it is expressed at the gene level, and the potential functionality of the marker. We have measured analytes on tissue/cellular extracts, serum/plasma, brochoalveolar lavage fluid, cerebrospinal fluid, entrometrial fluid, tears, amniotic fluid, and cell culture supernatants. The source of sample evaluated has come from mice, rats, rabbits, humans, and monkeys. Our Core is unique in that it is investigator friendly, working with clients on sample management, volume, appropriate process, and ultimately the best technical methods that optimizes the potential for success. We also have extensive experience in the development of assays not commercially available in any of the formats listed on the Core Supplies page. The interactions between the Core and the investigators is intially through the Core Director who has been doing these types of studies for several years and is diplomat certified by the American Board of Medical Laboratory Immunologists. This certification provides the infastructure for clinical translation with CLIA approved methodologies ans statistical analysis. Further, with our extensive volume we provide for our investigators the option to purchase reagents through our Core at a significant discount relative to buying from the company directly. Finally, we seek to offer these services for anaylsis of samples, but also to provide instruction of basic immunological and cellular techniques associated with these procedures and sample procurement.

Cleveland, Ohio 44106Located on the 8th floor of the BRB, The Bioanalyte Core utilizes quantitative and qualitative assays to measure bioanalytes such as cytokines, lipid metabolites, inflammatory markers. The analysis includes measuring soluble production of the bioanalyte, how it is expressed at the gene level, and the potential functionality of the marker. We have measured analytes on tissue/cellular extracts, serum/plasma, brochoalveolar lavage fluid, cerebrospinal fluid, entrometrial fluid, tears, amniotic fluid, and cell culture supernatants. The source of sample evaluated has come from mice, rats, rabbits, humans, and monkeys. Our Core is unique in that it is investigator friendly, working with clients on sample management, volume, appropriate process, and ultimately the best technical methods that optimizes the potential for success. We also have extensive experience in the development of assays not commercially available in any of the formats listed on the Core Supplies page. The interactions between the Core and the investigators is intially through the Core Director who has been doing these types of studies for several years and is diplomat certified by the American Board of Medical Laboratory Immunologists. This certification provides the infastructure for clinical translation with CLIA approved methodologies ans statistical analysis. Further, with our extensive volume we provide for our investigators the option to purchase reagents through our Core at a significant discount relative to buying from the company directly. Finally, we seek to offer these services for anaylsis of samples, but also to provide instruction of basic immunological and cellular techniques associated with these procedures and sample procurement.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Laser Capture Microdissection Core offers the ability to directly extract single cells from any tissue section, providing a pure cell population for subsequent quantitative analysis.

1801 East 101st Street Cleveland, OH, 44106 United StatesThe SMDD Core enables high-throughput screening of small-molecule libraries ('drug screening'). We have the automation equipment, libraries, and experienced personnel to support a wide range of assay development projects, including target-based/biochemical and cell-based/phenotypic assays.

1801 E. 101st Street, Cleveland Center for Membrane and Structural BiologyThe SMDD Core enables high-throughput screening of small-molecule libraries ('drug screening'). We have the automation equipment, libraries, and experienced personnel to support a wide range of assay development projects, including target-based/biochemical and cell-based/phenotypic assays.

3341 Warrensville Center Rd # 101 Shaker Heights, OH 44122Chemilan provides chemical synthesis, chemical manufacturing, APIs, and screening libraries.

Shaker Heights, OH United StatesChemilan provides chemical synthesis, chemical manufacturing, APIs, and screening libraries.

Cleveland, OH, 44106 United StatesThis core previously functioned under the Virology, Proteomics and Microbial Pathogenesis Core but has emerged into its own core. Dr. Chance is Director of Center for Proteomics and Bioinformatics, and acts as Proteomics and Systems Biology Core Director for the CFAR. He has a long-standing track record in quantitative mass spectrometry; his laboratory invented mass spectrometry based protein foot printing, a well-known and popular quantitative proteomics technology for examining protein structure.

Cleveland, Ohio 44106This core previously functioned under the Virology, Proteomics and Microbial Pathogenesis Core but has emerged into its own core. Dr. Chance is Director of Center for Proteomics and Bioinformatics, and acts as Proteomics and Systems Biology Core Director for the CFAR. He has a long-standing track record in quantitative mass spectrometry; his laboratory invented mass spectrometry based protein foot printing, a well-known and popular quantitative proteomics technology for examining protein structure.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Cardiovascular Imaging Core provides a wide range of imaging techniques to investigators at Cincinnati Children’s, and offers consulting services ranging from educational seminars to assistance with grant and industry funding support.

Columbus, OH United StatesChemical Abstracts Service provides patent search services.

2540 Olentangy River Road Columbus, OH 43202 U.S.A.Chemical Abstracts Service provides patent search services.

Monroe, OH United StatesCeltein Biosciences offers contract manufacturing and consulting in the areas of ELISA & cellular assay development, recombinant protein production and antibody development. Additionally, we consult & contract in the areas of gene cloning, plasmid generation and optimized protein expression.

6 Belmont Lane Monroe, OH 45050Celtein Biosciences offers contract manufacturing and consulting in the areas of ELISA & cellular assay development, recombinant protein production and antibody development. Additionally, we consult & contract in the areas of gene cloning, plasmid generation and optimized protein expression.

10900 Euclid Avenue Cleveland, OH, 44106 United StatesThe Hematopoietic Biorepository and Cellular Therapy Core serves as a resource for procurement, processing, storage, banking, analysis, and distribution of cells derived from clinical-grade production, human blood, bone marrow, and umbilical cords. The core is comprised of two components: A human hematopoietic biorepository and support services to facilitate basic hematopoietic research A clinical Cellular Therapy Lab that manufactures clinical-grade cell products for investigational and standard of care therapies

10900 Euclid Ave., Cleveland, Ohio 44106The Hematopoietic Biorepository and Cellular Therapy Core serves as a resource for procurement, processing, storage, banking, analysis, and distribution of cells derived from clinical-grade production, human blood, bone marrow, and umbilical cords. The core is comprised of two components: A human hematopoietic biorepository and support services to facilitate basic hematopoietic research A clinical Cellular Therapy Lab that manufactures clinical-grade cell products for investigational and standard of care therapies

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Gene Expression Microarray Core offers expression level analysis of thousands of genes in parallel.

9500 Euclid Avenue Cleveland, Ohio 44195This division of the Imaging Core offers a full array of histology services meeting the highest standards. Complete histology work — from cassetting of fixed specimens to the finished slides Highly skilled staff with broad experience Consultation and help with planning histology experiments Paraffin and frozen sectioning Standard and special stains

Cleveland, OH, 44106 United StatesThe CTSC BERD comprises experts in epidemiology and biostatistics across the CTSC's Partner Institutions. They provide a shared infrastructure of epidemiological and biostatistical resources to support CTSC researchers in three key areas: Development of optimal study designs and statistical analysis plans for study protocols: BERD experts provide free support for the development of research protocols submitted to funding agencies. Support typically includes development of an appropriate study design, statistical analysis plan, and corresponding budget for statistical support. When an investigator requests protocol development support, a BERD member will contact the investigator to discuss the availability of BERD support within 48 hours of the request. Requests made less than 4 weeks in advance of a deadline are not guaranteed to receive BERD support. Development of novel study designs and statistical methods that can be applied to translational research: BERD experts in statistical modeling, medical imaging, health outcomes research, informatics, statistical genetics, and genomics develop collaborative relationships with CTSC researchers interested in developing novel methodologies or statistical analysis tools. These collaborations often address problems that lack off-the-shelf solutions and accelerate movement along the 'discovery pathway' from laboratory to improved human health. Educating and mentoring early stage investigators (basic scientists, clinicians, epidemiologists, and biostatisticians) in study design and statistical analysis: Through a variety of seminars, workshops, and courses, BERD experts educate early stage investigators in topics ranging from study design to statistical analysis. BERD experts also mentor early stage investigators both informally (via office hours) and formally (by serving as advisors on thesis committees or named mentors on career development awards).

Cleveland, Ohio 44106The CTSC BERD comprises experts in epidemiology and biostatistics across the CTSC's Partner Institutions. They provide a shared infrastructure of epidemiological and biostatistical resources to support CTSC researchers in three key areas: Development of optimal study designs and statistical analysis plans for study protocols: BERD experts provide free support for the development of research protocols submitted to funding agencies. Support typically includes development of an appropriate study design, statistical analysis plan, and corresponding budget for statistical support. When an investigator requests protocol development support, a BERD member will contact the investigator to discuss the availability of BERD support within 48 hours of the request. Requests made less than 4 weeks in advance of a deadline are not guaranteed to receive BERD support. Development of novel study designs and statistical methods that can be applied to translational research: BERD experts in statistical modeling, medical imaging, health outcomes research, informatics, statistical genetics, and genomics develop collaborative relationships with CTSC researchers interested in developing novel methodologies or statistical analysis tools. These collaborations often address problems that lack off-the-shelf solutions and accelerate movement along the 'discovery pathway' from laboratory to improved human health. Educating and mentoring early stage investigators (basic scientists, clinicians, epidemiologists, and biostatisticians) in study design and statistical analysis: Through a variety of seminars, workshops, and courses, BERD experts educate early stage investigators in topics ranging from study design to statistical analysis. BERD experts also mentor early stage investigators both informally (via office hours) and formally (by serving as advisors on thesis committees or named mentors on career development awards).

Cleveland Clinic 9500 S Euclid Avenue, Room NE5-253 Cleveland, OH 44195Welcome to the Genomics Core of Cleveland Clinic’s Lerner Research Institute (LRI)! Our mission is to provide easy access to state-of-the-art DNA and RNA services to Cleveland Clinic’s investigators and to both external academic and commercial users. The Genomics Core uses cutting-edge genomics technology to generate top-quality data with a rapid turn-around time and an affordable cost. We offer a wide range of services, including capillary sequencing and genotyping, Illumina microarray-based gene expression profiling and genotyping, and next-generation sequencing (NGS). Our lab is equipped with the renowned Illumina MiSeq desktop sequencer and the Illumina HiSeq2500, which enable rapid and effective targeted and whole genome analyses. We prepare and normalize libraries for RNA-seq, miRNA-seq, DNA-Seq, ChIP-seq, targeted exome sequencing, amplicon sequencing, bacterial 16S metagenomics and whole genome sequencing. Other services include DNA/RNA QC on an Agilent Technologies Bioanalyzer, shearing of DNA and chromatin with Covaris technology, and microarray data analysis support. We also collaborate with the Genomic Medicine Biorepository to extract DNA and RNA for our users.

Cincinnati, OH United StatesCamargo Pharmaceutical Services offers CMC services, phase I-IV clinical services, pharmacokinetics, and consultation.

10151 Carver Road Suite 200 Cincinnati, Ohio 45242-4760 USACamargo Pharmaceutical Services offers CMC services, phase I-IV clinical services, pharmacokinetics, and consultation.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Genomic Medicine Biorepository (GMB), established in 2005, is a full-service processing and banking laboratory, which operates under the direction of Dr. Charis Eng, MD, PhD, Chair of the Genomic Medicine Institute (GMI). The GMB serves as the foundation for evidence-based research for the GMI, the Cleveland Clinic, and our collaborators. Our biorepository has received, catalogued, processed, and banked in excess of 90,000 specimens from more than 10,000 patients. These samples are of numerous tissue types from patients and their family members located all over the world. The GMB has managed specimens that have resulted in more than 300 original peer-reviewed articles and greater than $25 million total direct costs in extramural funding over the last 7 years. Samples received by the GMB are processed into a wide range of biomaterials using standardized laboratory techniques and quality control practices. Our services include the isolation of DNA and RNA for genetic studies, isolation of plasma or extraction of protein for proteomic studies, creation of immortalized cell lines from blood lymphocytes for biochemical research, and more. All sample information is entered into a laboratory information management system database (Labmatrix) for cataloguing, coding, and storage as well as integration of additional research data. The GMB works closely with investigators and is committed to meet their comprehensive study goals.

12150 Best Place Cincinnati, Ohio 45241-1569 USACelsus Laboratories manufacture derivatives of crude heparin and pursue the development of related complex carbohydrates for unmet medical and biomedical needs.

9500 Euclid Avenue Cleveland, Ohio 44195Cleveland Clinic’s Clinical Research Unit (CRU) provides an environment to conduct high-quality, compliant clinical research. The unit provides both inpatient and outpatient settings for research participants involved in studies by investigators. The CRU is located on the 5th floor of the M building at Desk M51 on the main campus. The 6,825 square-foot unit includes examination and procedure rooms, a processing laboratory, specialized research equipment, a conference room, and more. Our trained nursing and laboratory staff provide a safe, controlled environment for investigators to conduct state-of-the-art patient-oriented research studies. Who we serve: The CRU supports all levels of investigators including those in training. We encourage investigators who have research project funding from the NIH or other Federal agencies, foundations, industries or other peer-reviewed sources to apply to use the resources of the Clinical Research Unit. (Pilot projects are also considered eligible if there is a plan to seek extramural funding). Caregiver’s Achievement: The entire M51 CRU Team was selected as a 2013 Team Caregiver Awardee! This institution-wide recognition shows the reach we have for great research support we provide.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThis division of the Imaging Core provides investigators with a full range of electron microscopy services — from expert advice to sample preparation and observation in high quality instruments. Some experiments require a greater resolving power (or "higher magnification") than is possible with light (photon)-based microscopes. Since the wavelengths of electrons are much shorter than those of visible light, the EM makes it possible to examine the ultrastructure of biological materials (such as microorganisms and cells), a variety of large molecules, medical biopsy samples, as well as metals and the characteristics of various surfaces. Electron Microscopy services comprise both transmission and scanning electron microscopy (TEM and SEM). TEM services include normal processing of samples, thick or ultra-thin sectioning, staining, and image acquisition in the microscope. Sub-cellular localization of antigens by immunogold labeling can also be performed. SEM services include assistance with sample preparation, training in the use of the microscope, and elemental microanalysis.

9500 Euclid Avenue Cleveland, Ohio 44195This division of the Imaging Core provides investigators with a full range of electron microscopy services — from expert advice to sample preparation and observation in high quality instruments. Some experiments require a greater resolving power (or "higher magnification") than is possible with light (photon)-based microscopes. Since the wavelengths of electrons are much shorter than those of visible light, the EM makes it possible to examine the ultrastructure of biological materials (such as microorganisms and cells), a variety of large molecules, medical biopsy samples, as well as metals and the characteristics of various surfaces. Electron Microscopy services comprise both transmission and scanning electron microscopy (TEM and SEM). TEM services include normal processing of samples, thick or ultra-thin sectioning, staining, and image acquisition in the microscope. Sub-cellular localization of antigens by immunogold labeling can also be performed. SEM services include assistance with sample preparation, training in the use of the microscope, and elemental microanalysis.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesDo you have questions about IRB applications? Do you need advice on how to write consent forms? The Translational Research Core offers the services of a Clinical Research Coach. We can help with IRB questions including webkit. We are also experienced in not only writing consents but in contacts for contacting subjects. We can also coach on how to approach your research subjects. These services provided by the Translational Research Core are free of charge. The Translational Research Core offers services including consultations with a Clinical Research Coach, phlebotomy and access to pre-clinical animal operating theaters. Most of these capabilities are offered free of charge. For further description and contact information please see the "services" section of this page.

9500 Euclid Avenue Cleveland, Ohio 44195Do you have questions about IRB applications? Do you need advice on how to write consent forms? The Translational Research Core offers the services of a Clinical Research Coach. We can help with IRB questions including webkit. We are also experienced in not only writing consents but in contacts for contacting subjects. We can also coach on how to approach your research subjects. These services provided by the Translational Research Core are free of charge. The Translational Research Core offers services including consultations with a Clinical Research Coach, phlebotomy and access to pre-clinical animal operating theaters. Most of these capabilities are offered free of charge. For further description and contact information please see the "services" section of this page.

Cleveland, OH, 44106 United StatesA core group of clinical research technical leaders, informaticists, information technology specialists, and others from each of the five CTSC Partner Institutions provide and manage shared IT and informatics resources that make effective implementation of the entire program possible. These include a wide array of services, such as computerized tools, systems, underlying connectivity, and computer security required to support the multi-faceted clinical and translational research undertaking. This Core Resource is focused on short-, mid-, and long-term goals to serve the administrative needs of the CTSC, to improve and expand investigator and research data management support, and to develop and manage federated data repository and information sharing research portals across local institutions and nationally. A sampling of the comprehensive services they provide: The CTSC public website, listservs, teleconference serves, meeting scheduling, web demonstrations, online survey development Technical evaluations and recommendations for research projects, research data management support, connections to free or low-cost or highly customized research application and database systems, and assistance finding IT and informatics tools or expertise across the national clinical and translational science initiative. Access to various local systems, data, knowledge and experts in: electronic medical records systems (EpiCare at Cleveland Clinic and MetroHealth), clinical trial management systems (Velos and Oncore), biospecimen repositories Cooperative policy and data sharing agreement among the partner institutions Referrals to outside research organizations (i.e. NIH, NCRR, caBIG), standards development organization (i.e. CDISC, HL7), or professional associations (i.e. AMIA, HIMSS, Clinical Research Forum).

Cleveland, Ohio 44106A core group of clinical research technical leaders, informaticists, information technology specialists, and others from each of the five CTSC Partner Institutions provide and manage shared IT and informatics resources that make effective implementation of the entire program possible. These include a wide array of services, such as computerized tools, systems, underlying connectivity, and computer security required to support the multi-faceted clinical and translational research undertaking. This Core Resource is focused on short-, mid-, and long-term goals to serve the administrative needs of the CTSC, to improve and expand investigator and research data management support, and to develop and manage federated data repository and information sharing research portals across local institutions and nationally. A sampling of the comprehensive services they provide: The CTSC public website, listservs, teleconference serves, meeting scheduling, web demonstrations, online survey development Technical evaluations and recommendations for research projects, research data management support, connections to free or low-cost or highly customized research application and database systems, and assistance finding IT and informatics tools or expertise across the national clinical and translational science initiative. Access to various local systems, data, knowledge and experts in: electronic medical records systems (EpiCare at Cleveland Clinic and MetroHealth), clinical trial management systems (Velos and Oncore), biospecimen repositories Cooperative policy and data sharing agreement among the partner institutions Referrals to outside research organizations (i.e. NIH, NCRR, caBIG), standards development organization (i.e. CDISC, HL7), or professional associations (i.e. AMIA, HIMSS, Clinical Research Forum).

3333 Burnet Ave. MLC 7013 Cincinnati, OH 45229-3039 USACincinnati Children's Hospital Medical Center Humanized Mouse Resource Core is a comprehensive resource facility that provides a full range of xenograft mouse strains and services.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Media preparation lab offers a wide variety of quality controlled media at economical prices. Media is prepared in large batches ranging from 50L-250L from commercially produced powders. All of our products go through a strict QC program . Custom plates and media are offered by request and are usually available within 1-3 days. All other orders placed on-line can be picked up on the next business day. The Media Core services are very convenient and cost-effective.

9500 Euclid Avenue Cleveland, Ohio 44195The Media preparation lab offers a wide variety of quality controlled media at economical prices. Media is prepared in large batches ranging from 50L-250L from commercially produced powders. All of our products go through a strict QC program . Custom plates and media are offered by request and are usually available within 1-3 days. All other orders placed on-line can be picked up on the next business day. The Media Core services are very convenient and cost-effective.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Research Flow Cytometry Core is a shared resource laboratory serving the Cincinnati Children’s research communities and surrounding institutions by providing a central location for flow cytometry instrumentation, training and education.

9500 Euclid Avenue Cleveland, Ohio 44195The MDS Engineering Core team consists of mechanical, biomedical and materials engineers who focus on research and development related to new medical devices. We have over eight decades of combined engineering experience from a variety of backgrounds. Our team uses state-of-the-art tools to complement our experience, including Computer Aided Design, Digital Anatomic Reconstruction and Rapid Prototyping (see Services for more information). We have the unique position of having access to Cleveland Clinic physicians and surgeons and the support and infrastructure of the Cleveland Clinic, while at the same time having the operational flexibility of a small business .

10900 Euclid Ave., LC4960 Wood Bldg. W200 Cleveland, OH 44106 USACase Western Reserve University Center for Aids Research offers their core facilities to provide clinical, immunology, virology, microbial pathogenesis, and proteomic services.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Electronics Core is a fee-for-service electronics design, development and repair facility located on the first floor of the Lerner Research Institute at Cleveland Clinic. We specialize in proof-of-concept design and prototyping, and early stage development of medical devices and laboratory research instrumentation. We have the facilities and personnel to turn concepts into fully functional prototypes with most or all of the work performed in-house. This includes system design, schematic capture, printed circuit board layout, board fabrication, assembly and testing. Each member of our team of engineering professionals has more than 20 years of experience solving complex problems and creating intellectual property for our clients. Our collocation with the world class physicians, scientists and facilities of the Cleveland Clinic provides a unique advantage.

9500 Euclid Avenue Cleveland, Ohio 44195The Electronics Core is a fee-for-service electronics design, development and repair facility located on the first floor of the Lerner Research Institute at Cleveland Clinic. We specialize in proof-of-concept design and prototyping, and early stage development of medical devices and laboratory research instrumentation. We have the facilities and personnel to turn concepts into fully functional prototypes with most or all of the work performed in-house. This includes system design, schematic capture, printed circuit board layout, board fabrication, assembly and testing. Each member of our team of engineering professionals has more than 20 years of experience solving complex problems and creating intellectual property for our clients. Our collocation with the world class physicians, scientists and facilities of the Cleveland Clinic provides a unique advantage.

Cleveland, OH, 44106 United StatesA distinguishing characteristic and highlight of the CWRU CFAR is the strong emphasis it places on international biomedical research, with a particular focus on developing countries. The longstanding 25+ year research relationship between CWRU, primarily represented by the CWRU CFAR and the CWRU TBRU, the government of Uganda and Makerere University has led to the development of an extensive research infrastructure in Uganda. CWRU was one of the first US academic institutions to integrate a research approach involving teaching, training, and employment. Currently over 200 Ugandan scientists and health care professionals are actively involved in our collaborative programs. A major limitation to new initiatives in the developing world is the lack of state-of-the-art laboratory facilities on site. The Case CFAR has fostered seminal studies on TB and HIV/AIDS by providing a state-of-the-art laboratories and facilities for clinical virology and molecular biology in Uganda. All the research laboratories Virology/Molecular Biology, Immunology, Mycobacterial, and STD laboratories are directed on site by Ugandans, all of whom have received advanced degrees from CWRU through the Fogarty AIDS Training Program. The specific objectives of the Uganda Laboratory Core To provide comprehensive laboratory services to facilitate HIV/AIDS-related research projects of CFAR investigators To advertise these services, process requests, and coordinate research-based assays through the Uganda Laboratory Core To provide a mechanism for training of Ugandan scientists in collaboration with CWRU and Fogarty AIDS Training Grant

Cleveland, Ohio 44106A distinguishing characteristic and highlight of the CWRU CFAR is the strong emphasis it places on international biomedical research, with a particular focus on developing countries. The longstanding 25+ year research relationship between CWRU, primarily represented by the CWRU CFAR and the CWRU TBRU, the government of Uganda and Makerere University has led to the development of an extensive research infrastructure in Uganda. CWRU was one of the first US academic institutions to integrate a research approach involving teaching, training, and employment. Currently over 200 Ugandan scientists and health care professionals are actively involved in our collaborative programs. A major limitation to new initiatives in the developing world is the lack of state-of-the-art laboratory facilities on site. The Case CFAR has fostered seminal studies on TB and HIV/AIDS by providing a state-of-the-art laboratories and facilities for clinical virology and molecular biology in Uganda. All the research laboratories Virology/Molecular Biology, Immunology, Mycobacterial, and STD laboratories are directed on site by Ugandans, all of whom have received advanced degrees from CWRU through the Fogarty AIDS Training Program. The specific objectives of the Uganda Laboratory Core To provide comprehensive laboratory services to facilitate HIV/AIDS-related research projects of CFAR investigators To advertise these services, process requests, and coordinate research-based assays through the Uganda Laboratory Core To provide a mechanism for training of Ugandan scientists in collaboration with CWRU and Fogarty AIDS Training Grant

6701 Carnegie Avenue Cleveland, OH, 44103 United StatesAid clinicians in identifying risk and reducing cardiovascular events.

Cleveland, OH, 44106 United StatesThe CRUS provides highly experienced staff and dedicated research facilities for the conduct of clinical and translational studies. The focus of the CRUS is to provide safe, controlled and supportive research environments for adult and pediatric projects. Facilities are associated with each of the 3 CTSC partner institutions — The Cleveland Clinic, MetroHealth and University Hospitals -- and are available to both junior and senior investigators. Research resources are customized to meet investigator needs and include: Facilities: inpatient, outpatient and community-based; Staffing: research-trained nurses, bionutritionists, lab personnel and study coordination staff offer facility-based or deployable services; Services include: Bionutrition: anthropometrics (neonatal specialty), metabolic kitchen, dietary recall using NDSR Lab: sample processing & shipping, research analytical services Informatics: REDCap database development, Explorys training Fee-for-service study coordinator services The CRUS administrators at each of the 3 institutions collaborate with their respective institutions' Research Administration office to support investigators and their teams through the entire research process – project start-up through completion.

Cleveland, Ohio 44106The CRUS provides highly experienced staff and dedicated research facilities for the conduct of clinical and translational studies. The focus of the CRUS is to provide safe, controlled and supportive research environments for adult and pediatric projects. Facilities are associated with each of the 3 CTSC partner institutions — The Cleveland Clinic, MetroHealth and University Hospitals -- and are available to both junior and senior investigators. Research resources are customized to meet investigator needs and include: Facilities: inpatient, outpatient and community-based; Staffing: research-trained nurses, bionutritionists, lab personnel and study coordination staff offer facility-based or deployable services; Services include: Bionutrition: anthropometrics (neonatal specialty), metabolic kitchen, dietary recall using NDSR Lab: sample processing & shipping, research analytical services Informatics: REDCap database development, Explorys training Fee-for-service study coordinator services The CRUS administrators at each of the 3 institutions collaborate with their respective institutions' Research Administration office to support investigators and their teams through the entire research process – project start-up through completion.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Pyrosequencing Lab for Genomic and Epigenomic Research offers pyrosequencing to facilitate the study of epigenetic regulation mechanisms underlying normal development and disease pathogenesis.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe Mechanical Prototype staff is highly skilled in a variety of fabrication, customization and repair services for mechanical devices and equipment. We are proficient in precision machining of metals and plastics, welding of structural and exotic metals, instrument refurbishing and mechanical repair. Our personnel can work from concept sketches to design and fabricate new devices, test research fixtures and equipment. Documentation of the newly created part or device is also available through two-or three-dimensional computer-aided design (CAD) drawings. We also use SolidWorks and AutoCAD software. CAD drawings can be converted into computer-aided manufacturing (CAM) programs that are directly fed into the Computer Numerical Control (CNC) machines or Rapid Prototyping machines to fabricate the desired parts.

9500 Euclid Avenue Cleveland, Ohio 44195The Mechanical Prototype staff is highly skilled in a variety of fabrication, customization and repair services for mechanical devices and equipment. We are proficient in precision machining of metals and plastics, welding of structural and exotic metals, instrument refurbishing and mechanical repair. Our personnel can work from concept sketches to design and fabricate new devices, test research fixtures and equipment. Documentation of the newly created part or device is also available through two-or three-dimensional computer-aided design (CAD) drawings. We also use SolidWorks and AutoCAD software. CAD drawings can be converted into computer-aided manufacturing (CAM) programs that are directly fed into the Computer Numerical Control (CNC) machines or Rapid Prototyping machines to fabricate the desired parts.

Cincinnati, OH United StatesCincinnati Children's Hospital Medical Center Confocal Imaging Core provides single-photon and multi-photon laser scanning confocal imaging.

3333 Burnet Avenue Cincinnati, OH 45229-3026 USACincinnati Children's Hospital Medical Center Confocal Imaging Core provides single-photon and multi-photon laser scanning confocal imaging.

9500 Euclid Avenue Cleveland, OH, 44195 United StatesThe MSC is a core facility providing the use of high throughput screening technology (HTS), as well as expertise and reagents, necessary for the screening of the library of small molecules for biologically active compounds in a variety of readout systems. design & adjustment of readout systems; set-up and optimization of screening conditions and protocols; screening of diversified libraries of chemicals; data processing; assistance in designing program for chemically optimized lead compounds The MSC is a core facility providing the use of high throughput screening technology (HTS), as well as expertise and reagents, necessary for the screening of the library of small molecules for biologically active compounds in a variety of readout systems. The MSC can provide help with the adjustment of readout systems for both cell-based and biochemical assays and establishment of screening conditions based on a pilot small-scale screening. If successful, the established system is used for a full-scale library screening in 96 well format followed by generation of the database with the results. High throughput technology is not limited to drug discovery but can be used by any researcher to quickly conduct hundreds of thousands of biochemical, genetic or pharmacological tests. The Core is open for researchers at CCF and other biomedical research centers in the Cleveland area. shRNA Sigma mission shRNA clones

9500 Euclid Avenue Cleveland, Ohio 44195The MSC is a core facility providing the use of high throughput screening technology (HTS), as well as expertise and reagents, necessary for the screening of the library of small molecules for biologically active compounds in a variety of readout systems. design & adjustment of readout systems; set-up and optimization of screening conditions and protocols; screening of diversified libraries of chemicals; data processing; assistance in designing program for chemically optimized lead compounds The MSC is a core facility providing the use of high throughput screening technology (HTS), as well as expertise and reagents, necessary for the screening of the library of small molecules for biologically active compounds in a variety of readout systems. The MSC can provide help with the adjustment of readout systems for both cell-based and biochemical assays and establishment of screening conditions based on a pilot small-scale screening. If successful, the established system is used for a full-scale library screening in 96 well format followed by generation of the database with the results. High throughput technology is not limited to drug discovery but can be used by any researcher to quickly conduct hundreds of thousands of biochemical, genetic or pharmacological tests. The Core is open for researchers at CCF and other biomedical research centers in the Cleveland area. shRNA Sigma mission shRNA clones

9500 Euclid Avenue Cleveland, OH, 44195 United StatesCell culture work will be offered on an individual contractual basis. This will be an agreement between Cell Services personnel and the Researcher. At that time a plan will be drawn up, giving lead-time and estimated cost for the cell service. As part of our quality control program we have a Mycoplasma and Quarantine facility. The core will test for and eradicate mycoplasma from cell cultures. All cell culture is performed in a sterile environment employing aseptic techniques. The Cell Culture Core provides Cell Banking to Investigators. The Core has the capacity to freeze and store 10,000 vials. Any cells we receive for culturing will be quarantined until tested and found to be free from mycoplasma. The core has the following equipment Walk in warm room Walk in cold room Spinner apparatus to accommodate 20+L of cells in suspension Roller bottle machine to accommodate the culture of 200+ roller bottles Mycoplasma and Quarantine facilities Automated countess cell counter ELISA reader

9500 Euclid Avenue Cleveland, Ohio 44195Cell culture work will be offered on an individual contractual basis. This will be an agreement between Cell Services personnel and the Researcher. At that time a plan will be drawn up, giving lead-time and estimated cost for the cell service. As part of our quality control program we have a Mycoplasma and Quarantine facility. The core will test for and eradicate mycoplasma from cell cultures. All cell culture is performed in a sterile environment employing aseptic techniques. The Cell Culture Core provides Cell Banking to Investigators. The Core has the capacity to freeze and store 10,000 vials. Any cells we receive for culturing will be quarantined until tested and found to be free from mycoplasma. The core has the following equipment Walk in warm room Walk in cold room Spinner apparatus to accommodate 20+L of cells in suspension Roller bottle machine to accommodate the culture of 200+ roller bottles Mycoplasma and Quarantine facilities Automated countess cell counter ELISA reader

11100 Euclid Avenue Cleveland, Ohio 44106-5065Case Comprehensive Cancer Center provides antibody, imaging, gene expession, genotyping, sequencing, cytometry, xenograft, histology, proteomics, and hybridoma services.

681 W. Waterloo Rd. Akron, OH 44314We take pride in our ability to work closely and collaboratively with companies both large and small to manage their juice and packaging needs. Our growing list of well-respected customers is proof of our dedication to quality, competitive pricing and knowledgeable customer service.

9500 Euclid Avenue Cleveland, OH 44195 USACleveland Clinic focuses on research and offers its facilities to provide contract services.

Cincinnati, OH United StatesCincinnati Children's Hospital Medical Center offers its research cores to support studies in many areas of interest including animal behavior, in vivo imaging, gene expression, transgenic animals, pathology, viral vectors, DNA sequencing, and protein characterization.

3333 Burnet Avenue Cincinnati, OH 45229-3039 USACincinnati Children's Hospital Medical Center offers its research cores to support studies in many areas of interest including animal behavior, in vivo imaging, gene expression, transgenic animals, pathology, viral vectors, DNA sequencing, and protein characterization.

9500 Euclid Avenue, Mailstop NC10, Cleveland, OH 44195The Center for Cardiovascular Diagnostics and Prevention offers analysis of whole blood CBCs as a core service. Testing is performed on a multi-species capable Advia 120 Hematology analyzer. The following tests are available: Complete Blood Count (CBC) CBC plus white cell differential counts (CBC/Diff) Absolute and percent Reticulocyte Count (Retic)* CBC/Diff plus retic (CBC/diff/retic)* CBC/retic

OH, 44233 United StatesClinicalRM is a full service Contract Research Organization (CRO) specializing in support of clinical research, clinical trial services for biologics, drugs, and devices.

ClinicalRM, Inc. 1265 Ridge Road Ste. A Hinckley, OH 44233ClinicalRM is a full service Contract Research Organization (CRO) specializing in support of clinical research, clinical trial services for biologics, drugs, and devices.

11100 Euclid Avenue Lakeside 3500 Cleveland, OH 44106 USACase Western Reserve University Transgenic & Targeting Facility offers transgenic animal models, vector construction, and cryopreservation services.

Columbus, OH United StatesThe Clinical Trials Office Shared Resource provides a centralized resource of comprehensive management services for the OSUCCC investigators to conduct successful clinical trials in a methodologically sound, expedient and cost-effective manner.

300 W. 10th Ave. Columbus, OH 43210The Clinical Trials Office Shared Resource provides a centralized resource of comprehensive management services for the OSUCCC investigators to conduct successful clinical trials in a methodologically sound, expedient and cost-effective manner.

1055 east State Street, Suite 100 Athens OH 45701Diagnostic Hybrids offers primary hepatocytes, specimen collection, multi-virus cell culture amplification, cell lines, and virus detection.

7000 Cardinal Place United States Dublin, OH, 43017 United StatesCardinal Health HEOR Oncology Team is uniquely equipped to offer AZ a comprehensive solution that engages our full service capabilities, including the in-house experience and expertise of our HEOR team, Chief Medical Officers, Clinical Oncology Nurse and Oncology Staff to conduct HEOR studies. We differentiates ourselves from other competitors by leveraging our Oncology Provider Network, Oncology Practice Network, conducting retrospective Claims and EMR studies, EMR linked to Claims studies, Claims and Physician Case Report Form studies, literature reviews, Patient Reported Outcomes and Physician Case Report Form (chart review/chart abstraction) studies.

1117 Broadview Avenue Columbus, OH, 43212 United StatesCALDEZ Consulting assists companies by bringing new products & services to market, assisting with prospect engagement, penetrating existing markets for additional untapped growth, expanding into new client segments, and exploring new channels of potential prosperity. We can assist with any stage of the sales process, from lead generation to contract negotiation.

20521 Chagrin Blvd Shaker Heights, OH, 44122 United StatesCTL offers products and services for immune assays. These include a library of cryopreserved human PBMC with HLA-typed donors that have established T cell reactivity. We specialize in immune characterization through ELISPOT, providing ImmunoSpot analyzers, ImmunoSpot kits, hands-on wetlab training, consultation, and GLP contract research.

14656 Neo Parkway Garfield Heights, OH, 44128 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

640 North Elizabeth Street Spencerville, Ohio, 45887 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

14656 Neo Parkway Cleveland, Ohio, 44128 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

1407 George Road Ashland, Ohio, 44805 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Athens, OH, 45701 United StatesDiagnostic Hybrids offers primary hepatocytes, specimen collection, multi-virus cell culture amplification, cell lines, and virus detection.

5900 Landerbrook Drive, Suite 170 Mayfield Heights, OH 44124 USADATATRAK is the leader of unified eClinical technologies and related services for the clinical trials industry. Using the DATATRAK ONE multi-product, cloud-based clinical research platform, DATATRAK’s Clinical and Consulting Services group assists clients in conducting Phase I-IV drug and device studies in multiple languages throughout the world.

1381 Dairy Lane P.O. Box 87 Orrville, OH 44667Dairy Enterprises Incorporated (DEI) is the company that brings you popular brands like SMITH’S, Ruggles and Yomazing! An industry leader in quality and innovation, DEI is dedicated to providing both our customers and consumers with the best products available and manufactured by our family of dairies: Smith Dairy, Wayne Dairy and Pacific Valley Dairy. This attention extends to food service, private label and contract packaging opportunities.

West Chester, Ohio, USADiaPharma offers antibodies, proteins, enzymes, coagulation, fibrinolysis, apoptosis, hepatology products and services.

West Chester, OH, 44699 United StatesDiaPharma offers antibodies, proteins, enzymes, coagulation, fibrinolysis, apoptosis, hepatology products and services.

1476 Manning Parkway Powell, OH, 43065 United StatesAsk us about our cell and gene therapy products, including both research and clinical use Discovery Leukopaks. Discovery Life Sciences are the Biospecimen & Biomarker Specialists™. We have the world’s largest biospecimen inventory and procurement network with preeminent multi-omic service laboratories to accelerate precision medicine programs in oncology, immuno-oncology, immunology, inflammation, infectious diseases, and beyond. We are pleased to announce ReachBio is now a part of Discovery Life Sciences. Our biobanks include more than 10 million biospecimens and we have hundreds of clinical sites (Discovery Partners®) that allow researchers to build bespoke study cohorts and seamlessly interrogate them using our CLIA certified, GLP-compliant service laboratories, including our world-renowned Genomic Sequencing and bioinformatics laboratory, HudsonAlpha Discovery, our expert IHC services laboratory that developed the pembrolizumab PD-L1 IHC companion diagnostic prototype, our Proteomic Services labs that offer Olink, Luminex, Seer Proteograph and Mass Spec protein profiling, and our Cell Biology laboratory provides extensive Flow cytometry and single cell RNASeq services with GMP-compliant leukapheresis products for cell therapy development and manufacturing. We also offer clinical flow cytometry services for analysis of trial samples. We are committed to quality and integrity with ISO 13485, GMP- and GCLP-compliant and CLIA-certified labs, stringent IRB and Ethics Committee compliance, and all required approvals and certifications. Navigating US and international personal data protection, drug development and diagnostic development regulations is one of our core competencies.

440 West Prospect Street Painesville, OH, 44077 United StatesEagle Laboratory Glass Company, LLC is a family owned and operated glass blowing company just outside of Cleveland, OH. We specialize in the fabrication and repair of borosilicate (often referred to as "Pyrex") lab glass. After 47 years of business, we have the skilled workers and the facilities to complete all orders quickly and expertly. Whether you need something as simple as a dozen test tubes or as involved as a totally custom never-before-produced design, we are the glass shop for you.

4955 Spring Grove Avenue Cincinnati, OH, 45232 United States

5138 Susetta Avenue Northwest Canton, OH, 44709 United StatesExCyte is the world’s leading flow cytometry training company. Whether you are a core manger looking to keep your users on the cutting edge, or a business professional looking to enter into this rapidly growing market, ExCyte can help. We have the information and experience you need. ExCyte is currently booking beginner and advanced flow cytometry courses around the world. Click on the Calendar box above to see where we will be next.

9140 Ravenna Road Unit #3 Twinsburg, OH 44087, USAExpo Technologies provides consultancy, engineering solutions, on-site services and training programs.

3650 Harris Rd Hamilton, OH, 45013 United StatesEquitech-Bio Inc. provides serum and plasma products, specialty reagents, antisera, custom antibodies, FBS, BSA, Albumins, IgG, IgY. Human Blood Products are produced by our sister company Equitech Enterprises, Inc. which is FDA Approved.

4900 Este Avenue, 45232 Cincinnati, Ohio, USAThomas Emery (Snr) started a tallow and candle business in 1840. A decade later, The Emery Candle Company offered customers sturdier, whiter, dripless candles made of stearic acid. Soon, the expanded product line also included elaine oil (oleic acid) and sweetwater (glycerine). By 1872, the company was involved in fatty acid exploration while growing an existing product line that included elaine oil (oleic acid) and sweetwater (glycerine). Click here to find more. Today, 174 years later, Emery Oleochemicals is a name synonymous with the production of high quality, natural-based chemicals commonly made from natural oils and fats. Our business is increasingly focused in high-value derivatives. Through our six dedicated business units , we have the ability to provide you with customisable, high-performance, market-based solutions. Backed by an extensive distribution network covering over 50 countries globally, Emery Oleochemicals applies its philosophy, Creating Value with our wide-ranging product portfolio for use in the home and personal care, construction, automotive, lubricants, packaging, food and beverage, pharmaceuticals, textiles, electrical and electronics, furniture and bedding, and agriculture industries. Headquartered in Shah Alam, Malaysia,our manufacturing facilities and sales and marketing offices are located in Asia Pacific, Europe and North America. We are backed by a diverse workforce of more than 1,000 people and an extensive distribution network covering over 50 countries globally.

2775 Henkle Dr. Lebanon, OH 45036 USAE-BEAM Services, Inc. is a leading supplier of contract electron beam processing services, with more than 450kW of installed accelerator capacity -- enough to process nearly one billion pounds of material annually.

2775 Henkle Drive Lebanon, OH, 45036 United StatesE-BEAM Services, Inc. is a leading supplier of contract electron beam processing services, with more than 450kW of installed accelerator capacity -- enough to process nearly one billion pounds of material annually.

1507 Chambers Road Suite 301 Columbus, OH, 43212 United StatesExoNanoRNA provides RNA/DNA/modified oligo synthesis, custom RNA nanoparticles, RNA aptamers, RNA therapeutics, RNA targeting vectors, exosomes, exosome loading, exosome purification, exosome surface functionalization

6700 Euclid Ave, Suite 101 - EVERSIGHT Suite 101 Cleveland, OH, 44103 United StatesEversight restores sight and prevents blindness through donation, transplantation and research. The eye bank network provides 8,000+ surgical grafts for transplant and 3,000+ ocular tissues for eye and vision research annually. Eversight research experts procure, process, preserve and distribute human ocular tissue with medical records to meet specific research needs. The Eversight Center for Vision and Eye Banking Research in Cleveland offers in-house R&D services that enable Eversight to serve as a CRO, conducting projects for external partners. Capabilities include: •Ex-vivo drug testing •Specular microscopy, light and fluorescence microscopy •Slit lamp and OCT imaging •Histology •Tissue dissection •RNA/DNA/protein isolation and quantification Operating in Arizona, Connecticut, Illinois, Michigan, New Jersey, Ohio and South Korea, Eversight works with surgeons, researchers, academic medical centers and eye banks worldwide.

3701 Port Union Road Fairfield, OH, 45014 United StatesElement’s Health Sciences Division offers consulting and analytical testing solutions for the pharmaceutical, medical device and biotech industries. Our facilities operate under GLP/GMP. We provide a wide range of CMC development services and clinical manufacturing (Phase I & II) for IND/NDA/ANDA drug products, specializing in parenteral, topical and ophthalmic products. We have an established expertise in method development & validation, harmonized compendia testing, E&L programs for manufacturing equipment, transdermal, inhalation, injectable, and combination medical device products. Our goal is to offer comprehensive solutions tailored for successful product approvals. Our relationships are built on expertise, partnerships and trust.

Enamine LLC 2940 Glendale Milford Road #410, Cincinnati, OH, 45241 United StatesThe main activities of the Company include: •Organic synthesis of Screening Compounds, Building Blocks, and Fragments •R&D services (custom synthesis, compound library design, hit follow-up support, and lead optimization) to support the research programs conducted by pharmaceutical and biotech companies, drug discovery centers, academic institutions and other research organizations worldwide.

11200 S.W. 8 Street, MARC 430 Miami, FL 33199-0001FIU’s Animal Care Facility is registered as a research facility with the United States Department of Agriculture (USDA) in accordance with the Animal Welfare Act and Regulations. The FIU Animal facility is inspected by the USDA to ensure that all activities involving research animals are in compliance with all applicable laws and regulations.

11811 Shaker Blvd, Suite 330 Cleveland, OH 44120 USAFertility Solutions offers sperm analysis products and services.

Cleveland, OH United StatesFertility Solutions offers sperm analysis products and services.

Toledo, OH United StatesFIBIO Drug Discovery is both a drug discovery company and contract service provider. The company offers comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, therapeutic antibody discovery, in vivo pharmacology, as well as other research and development services.

347 S. College Ste B Oxford, OH 45056 USAGerard Biotech supplies genomic DNA isolation and plasmid preparation kits.

Oxford, OH, 45056 United StatesGerard Biotech supplies genomic DNA isolation and plasmid preparation kits.

4354 Ferguson Drive Cincinnati, Ohio, 45245 United StatesStreamline workflow efficiencies and processes, eliminate errors and provide the best patient care with healthcare solutions from General Data. With our broad range of resources, including solutions for histology, positive patient identification, mobility, and printer fleet management, hospital staff can use these technologies to do what they do best: deliver optimal outcomes and the best possible care.

Bellevue, OH, USA 44811Welcome to GIS Ag Maps. The main purpose is to show and provide information in order that GIS and remote sensing can be applied for different purposes (there is a focus on crop agriculture). An emphasis is on applying Landsat imagery, yield maps, LiDAR-based elevation data and derived layers, as well as free GIS software.

7100 Euclid Avenue Suite 160 Cleveland, OH 44103 USAGenSyn Technologies provides custom particle engineering services to improve bioavailability and expand delivery system options of small molecule APIs.

5386 Majestic Parkway Bedford Heights, OH, 44146 United StatesGojira Fine Chemicals is a privately owned chemical/biochemical company specializing in global sourcing from qualified vendors and having traceable, transparent and sustainable processes.

8740 Montgomery Road Cincinnati, OH 45236 USAGenetica DNA Laboratories is one of the largest providers of paternity DNA tests, immigration DNA tests, adoption DNA tests, family relationship DNA tests, and identity DNA tests to the general public as well as to healthcare, legal professionals and embassies throughout the United States and worldwide.

Cincinnati, OH United StatesGenetica DNA Laboratories is one of the largest providers of paternity DNA tests, immigration DNA tests, adoption DNA tests, family relationship DNA tests, and identity DNA tests to the general public as well as to healthcare, legal professionals and embassies throughout the United States and worldwide.

Powell, OH, 43065 United StatesGFS Chemicals offers bulk chemicals and other laboratory reagents.

1350 Euclid Ave, Suite 1500 Cleveland, OH 44115

5700 Darrow Road, Suite 110 Hudson, OH 44236 United States

1476 Manning Pkwy Powell, OH, 43065 United StatesGnome Diagnostics (GnomeDX) is the Biomarker Analysis Company. It provides histopathology and molecular biology services for preclinical and clinical trials research and development in its CLIA-certified lab environment. Gnome is expert at performing 'difficult' studies for biotech and pharmaceutical clients, including immunohistochemistry (IHC) in situ hydridization (ISH) and multi-color co-expression studies

1476 Manniun Pkwy Powell, OH, 43065 United StatesGnome Diagnostics (GnomeDX) is the Biomarker Analysis Company. It provides histopathology and molecular biology services for preclinical and clinical trials research and development in its CLIA-certified lab environment. Gnome is expert at performing 'difficult' studies for biotech and pharmaceutical clients, including immunohistochemistry (IHC) in situ hydridization (ISH) and multi-color co-expression studies

5880 Innovation Drive Dublin, OH, 43016 United StatesFrom strategic planning, business process consulting, project implementation and support, we can integrate and build the right technology solutions for your organization.

Miamiville, OH United StatesHill Top Research provides safety testing, efficacy testing, microbiology, and clinical services.

6450 Castle Drive Mason, OH, 45040 United StatesStageBio provides necropsy, histology, veterinary pathology evaluation, immunohistochemistry, neuropathology, medical device, morphometry, whole slide scanning and archiving outsourcing support to the drug discovery companies. We work with a variety of species including: hamsters, mice, rats, ferrets, guinea pigs, rabbits, dogs, pigs, sheep and non-human primates.

6450 Castle Drive Mason, OH, 45040 United StatesStageBio provides necropsy, histology, veterinary pathology evaluation, immunohistochemistry, neuropathology, medical device, morphometry, whole slide scanning and archiving outsourcing support to the drug discovery companies. We work with a variety of species including: hamsters, mice, rats, ferrets, guinea pigs, rabbits, dogs, pigs, sheep and non-human primates.

107 Fallenoak Ct Loveland, OH 45140 USAIntegrated BioScience Solutions assists early to mid-stage biotechnology companies with the commercialization of their technologies by providing a full range of development services including early stage business and regulatory planning, and clinical trial implementation.

Loveland, OH United StatesIntegrated BioScience Solutions assists early to mid-stage biotechnology companies with the commercialization of their technologies by providing a full range of development services including early stage business and regulatory planning, and clinical trial implementation.

25 Whitney Drive • Milford, OH USA 45150Interplex Medical provides independent engineering and contract manufacturing of medical devices

5516 East Galbraith Road Cincinnati, OH 45236 USAIncelligen offers peptide synthesis, protein production, gene synthesis, in vivo PK, and hERG services.

Cincinnati, OH United StatesIncelligen offers peptide synthesis, protein production, gene synthesis, in vivo PK, and hERG services.

10000 Cedar Avenue Mailstop #18 Cleveland, OH 44106 USAImageIQ offers visual and data analysis through customized imaging analytics, software engineering and biomedical expertise.

777 Lena Drive Aurora, Ohio, 44202 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

5155 Financial Way Suite 17 Mason, Ohio, 45040 United StatesInnoSIGN offers its OncoSIGNal technology to gain insight into the functional activity of cellular signaling pathways. mRNA levels transcribed from direct target genes regulated by the pathway transcription factors are translated into pathway activity scores for the ER, AR, PI3K, MAPK, Hedgehog, TGFß, Notch, Wnt, NF-kB and JAK-STAT1/2 pathways, resulting in a quantitative characterization of the cell molecular phenotype. OncoSIGNal is available for clinical use in breast cancer as a lab-developed test through InnoSIGN's CLIA laboratory in Mason (OH), for research use through labs in the EU and US as a comprehensive testing service, or as a distributed PCR test for use in a customer laboratory. The analysis can also be run from RNA-seq data for various cancer and cell types. InnoSIGN utilizes its extensive database with more than 100,000 pathway activity profiles to support drug and diagnostics development. OncoSIGNal Products & Services for Research-Use-Only OncoSIGNal Test (G7) ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß pathways Compatible with FFPE samples from human origin RT-qPCR testing plates including quality checks on sample input and correct plate filling Result overview in dedicated OncoSIGNal Report Allows for in-house testing using standard laboratory equipment Developed under ISO13485 OncoSIGNal Service Testing ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß and/or Wnt, NF-kB and JAK-STAT1/2 pathways Compatible with FFPE tissue samples and RNA extracted from cell lines and tissue of human origin Extensive quality checks on samples, laboratory process and results Result overview in dedicated OncoSIGNal Report ISO13485 certified OncoSIGNal Data Service ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß and/or Wnt, NF-kB and JAK-STAT1/2 pathways Analysis of full transcriptome RNA sequencing data Compatible with FASTQ data files Extensive quality checks on samples and results Result overview in dedicated OncoSIGNal Report OncoSIGNal Laboratory Developed Test for clinical use Available in the US as LDT for breast cancer via InnoSIGN's CLIA laboratory (Mason, Ohio) ER, AR, PI3K, MAPK, Hedgehog, Notch and TGFß pathways Sample type: FFPE tissue Indication of tumor-driving pathways Guiding therapy decisions

5155 Financial Way Suite 17 Mason, Ohio, 45040 United StatesInnoSIGN offers its OncoSIGNal technology to gain insight into the functional activity of cellular signaling pathways. mRNA levels transcribed from direct target genes regulated by the pathway transcription factors are translated into pathway activity scores for the ER, AR, PI3K, MAPK, Hedgehog, TGFß, Notch, Wnt, NF-kB and JAK-STAT1/2 pathways, resulting in a quantitative characterization of the cell molecular phenotype. OncoSIGNal is available for clinical use in breast cancer as a lab-developed test through InnoSIGN's CLIA laboratory in Mason (OH), for research use through labs in the EU and US as a comprehensive testing service, or as a distributed PCR test for use in a customer laboratory. The analysis can also be run from RNA-seq data for various cancer and cell types. InnoSIGN utilizes its extensive database with more than 100,000 pathway activity profiles to support drug and diagnostics development. OncoSIGNal Products & Services for Research-Use-Only OncoSIGNal Test (G7) ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß pathways Compatible with FFPE samples from human origin RT-qPCR testing plates including quality checks on sample input and correct plate filling Result overview in dedicated OncoSIGNal Report Allows for in-house testing using standard laboratory equipment Developed under ISO13485 OncoSIGNal Service Testing ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß and/or Wnt, NF-kB and JAK-STAT1/2 pathways Compatible with FFPE tissue samples and RNA extracted from cell lines and tissue of human origin Extensive quality checks on samples, laboratory process and results Result overview in dedicated OncoSIGNal Report ISO13485 certified OncoSIGNal Data Service ER, AR, PI3K, MAPK, Hedgehog, Notch, TGFß and/or Wnt, NF-kB and JAK-STAT1/2 pathways Analysis of full transcriptome RNA sequencing data Compatible with FASTQ data files Extensive quality checks on samples and results Result overview in dedicated OncoSIGNal Report OncoSIGNal Laboratory Developed Test for clinical use Available in the US as LDT for breast cancer via InnoSIGN's CLIA laboratory (Mason, Ohio) ER, AR, PI3K, MAPK, Hedgehog, Notch and TGFß pathways Sample type: FFPE tissue Indication of tumor-driving pathways Guiding therapy decisions

7552 G St. Clair Avenue Mentor, OH 44060-5201

1200 University Esplanade, Kent, Ohio 44242

P. O. Box 181 Aurora, OH 44202 USAKarl Industries supplies over 1200 chemicals and offers custom synthesis and contract research services.

103 College Rd, Gambier, OH 43022Kenyon College is a private liberal arts college in Gambier, Ohio, United States, founded in 1824 by Philander Chase. It is the oldest private college in Ohio and is affiliated with the Episcopal Church.

103 College Rd Gambier, Ohio, 43022 United StatesKenyon College is a private liberal arts college in Gambier, Ohio, United States, founded in 1824 by Philander Chase. It is the oldest private college in Ohio and is affiliated with the Episcopal Church.

3838 S 700 E # 202Lifetree Research provides kinetic studies, first-in-man dose studies, bioavailability, drug-drug interactions, and quality assurance.

10760 West County Road 18 Fostoria, OH

168 East Ridge Road, Industrial Center, # 202, Linwood, PA 19061.USALouston offers API and custom synthesis services.

10701 East Boulevard Cleveland, OH 44106Louis Stokes Cleveland VA Medical Center offers a full range of primary, secondary and tertiary care services to an eligible Veteran population covering 24 counties in Northeast Ohio. Care is provided to more than 110,000 Veterans each year through an inpatient tertiary care facility (Wade Park), 13 Multi-Specialty Clinics, Vet Centers, and numerous community-based contract nursing homes. The medical center actively supports affiliation agreements, intra-agency agreements, medical education and research, training programs and broad-based research initiatives. Patient care services provided by the Louis Stokes Cleveland VA Medical Center are based on our mission, vision and values and we are committed to delivering the highest quality and safest health care to our Nation’s Veterans. We are aprt of the newly integrated VISN10 includes 10 medical centers and the independent Columbus, OH Ambulatory Care clinic and a network of 58 Community Based Outpatient Clinics. the independent Columbus, OH Ambulatory Care clinic and a network of 58 Community Based Outpatient Clinics.”

10701 East Boulevard Cleveland, OH, 44106 United StatesLouis Stokes Cleveland VA Medical Center offers a full range of primary, secondary and tertiary care services to an eligible Veteran population covering 24 counties in Northeast Ohio. Care is provided to more than 110,000 Veterans each year through an inpatient tertiary care facility (Wade Park), 13 Multi-Specialty Clinics, Vet Centers, and numerous community-based contract nursing homes. The medical center actively supports affiliation agreements, intra-agency agreements, medical education and research, training programs and broad-based research initiatives. Patient care services provided by the Louis Stokes Cleveland VA Medical Center are based on our mission, vision and values and we are committed to delivering the highest quality and safest health care to our Nation’s Veterans. We are aprt of the newly integrated VISN10 includes 10 medical centers and the independent Columbus, OH Ambulatory Care clinic and a network of 58 Community Based Outpatient Clinics. the independent Columbus, OH Ambulatory Care clinic and a network of 58 Community Based Outpatient Clinics.”

705 Front Street Toledo OH 43605 USALexaMed provides sterilty testing, microbial identifications, wet chemistry, elemental analysis, and method development.

247 East 9th Avenue Columbus, OH, 43201 United StatesWe can provide assistance with every part of the research life cycle including the location of hard-to-find materials and samples, 21cfr11 data management via selected ELN and LIMS software solutions, and the formation of strategic alliances to help your organization grow. We can also assist you with the recruitment of CLIA certified CROs, immunohistopathology & genomic labs and other research service providers that can help you complete key studies.

1393 Dublin Road,Leadscope a chemoinformatics data-mining and predictive platform. As a suite of tools, researchers have integrated access to chemistry-based data mining, visualization, and advanced informatics techniques (prediction tools,scaffold generators, etc.). The platform, coupled with our content databases, is a comprehensive in silico discovery solution.

29400 Lakeland Boulevard Wickliffe, OH, 44092 United States

2910 Harvard Avenue, Cleveland, OH 44105 USAMcGean offers specialty chemicals, inorganic intermediates, and manufacturing services.

Cleveland, OH United StatesMcGean offers specialty chemicals, inorganic intermediates, and manufacturing services.

7855 Division Drive Mentor, OH 44060 USAMerge Healthcare specializes in clinical systems and offers cloud-based solutions for imaging and data analytics.

501 East High Street | Oxford, Ohio 45056Miami University is committed to the ethical use of animals in research, teaching, and testing. All interactions with and provisions for the care of animals by Miami personnel or on property controlled by the university must be approved by the Institutional Animal Care and Use Committee (IACUC). In compliance with federal regulations, the IACUC members are appointed by the University President and are charged with assuring that Miami is in compliance with all applicable provisions of Public Health Service Policy, the Animal Welfare Act, and other relevant Federal statutes and regulations.

501 East High Street Oxford, , Ohio , 45056 United StatesMiami University is committed to the ethical use of animals in research, teaching, and testing. All interactions with and provisions for the care of animals by Miami personnel or on property controlled by the university must be approved by the Institutional Animal Care and Use Committee (IACUC). In compliance with federal regulations, the IACUC members are appointed by the University President and are charged with assuring that Miami is in compliance with all applicable provisions of Public Health Service Policy, the Animal Welfare Act, and other relevant Federal statutes and regulations.

3471 River Hills Drive Cincinnati, OH 45244 USAMeridian Bioscience provides diagnostic products, reagents, proficiency testing materials, and quality assurance.

1900 Polaris Parkway, Columbus, OH 43240Mettler Toledo Rainin provides pipettes, tips, accessories and calibration services.

2400 E. River Rd. Dayton, OH 45439

1280 Main Street WestMcMaster University focuses on research with facilities for microbiology, genomics, and gene therapy.

Miami University Oxford, Ohio 45056The Instrumentation Laboratory is a technological partner to teaching and research throughout Miami University by its support of instrumentation and laboratory equipment. This partnership is achieved through competent staff, suitably equipped facilities, and the array of services available to both faculty and students. Instrumentation Laboratory services are maintenance and repair of instruments, laboratory apparatus, and glassware; consultation and training on laboratory equipment; and design and construction of specialized apparatus. Facilities are the electrical and electronic laboratory, the mechanical laboratory and machine shop, and the welding shop. Multidisciplinary access to an inventory of major analytical instruments is provided. Services Maintenance and repair- The Instrumentation Laboratory provides routine and preventative maintenance and repair for instruments and laboratory apparatus. Consultation and Training- The Instrumentation Laboratory consults with faculty and students on a wide range of technical issues related to research, such as equipment purchase, instrument selection, and design. We train in user maintenance of instruments, and safety procedures. Design and Construction of Specialized Apparatus- The Instrumentation Laboratory staff has the engineering and technological skills to design and construct many types of instruments, apparatus, and accessories. Complex glassware, mechanisms from well drilling rigs to miniature sample cell manifolds, and amplifiers, filters, timers, computer interfaces, and software have been designed and built by the Instrumentation Laboratory. The IL is now offers design and support of projects using the LabVIEW System Design Software. Instrument Accessibility- The Instrumentation Laboratory provides interdisciplinary access to major research instruments located in the science departments. Specialized instruments important to two or more research groups are made accessible to all researchers by inclusion on the Instrumentation Laboratory's Equipment List. Questions- If you have questions about any of these services, please contact the Instrumentation Lab.

4750 Wesley Avenue, Suite Q, Cincinnati, Ohio 45212, USAMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

4685 Forest Avenue, Suite B, Cincinnati, Ohio 45212, USAMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

4620 Wesley Avenue, Cincinnati, Ohio 45212, USAMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

5375 Medpace WayMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

5375 Medpace Way Cincinnati, OH, 45227 United StatesMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

3814 West Street Suite 220 Cincinnati, OH, 45227 United StatesMabtech develops and offers ELISpot, FluoroSpot and ELISA kits, kit components and reagents, ELISpot and FluoroSpot readers and Contract Lab Services.

23811 Chagrin Boulevard Cleveland, OH, 44122 United StatesMultiCASE Inc. is a pioneer in developing computer programs for assessing toxicological and pharmacological potential of chemicals and pharmaceuticals. Research and development is central to us in developing innovative QSAR methodologies and software solutions. The company has maintained strong academic ties in the areas of computational, medicinal, and environmental chemistry.

23811 Chagrin Blvd Suite 305 Beachwood, OH, 44122 United StatesMultiCASE Inc. is a pioneer in developing computer programs for assessing toxicological and pharmacological potential of chemicals and pharmaceuticals. Research and development is central to us in developing innovative QSAR methodologies and software solutions. The company has maintained strong academic ties in the areas of computational, medicinal, and environmental chemistry.

29525 Fountain Pkwy.MP Biomedicals is dedicated to giving scientists and researchers innovative, quality tools and superior service to aid them in their quest for ground-breaking discovery and turning the hope for life-changing solutions into a reality. The company manufactures and sells more than 55,000 products and is one of the only companies in the industry to offer a comprehensive line of life science, fine chemical and diagnostic products. MP Biomedicals is a world-wide corporation, with ISO-certified and FDA-approved manufacturing and distribution facilities throughout the globe and headquartered in Southern California. A vast network of global distributors and satellite facilities and offices throughout Europe, Asia, Australia and the Americas assures customers top quality products delivered when and where needed. No matter how dynamic the evolution of the life science and biotechnology markets, we remain committed to supporting our customers in their efforts to make new discoveries. From basic research, through scale-up, to full-scale production and diagnostic testing, MP Biomedicals serves every industry need – from specialized areas of research to supplying large scale quantities of fine chemicals. Our customers partner with us because they want a long-time player and reliable colleague in the fields of life science research and diagnostics. MP Biomedicals will never rest in our odyssey to remain at the forefront of discovery in the ever-changing biomedical industry.

Solon, OH, 44139 United StatesMP Biomedicals is dedicated to giving scientists and researchers innovative, quality tools and superior service to aid them in their quest for ground-breaking discovery and turning the hope for life-changing solutions into a reality. The company manufactures and sells more than 55,000 products and is one of the only companies in the industry to offer a comprehensive line of life science, fine chemical and diagnostic products. MP Biomedicals is a world-wide corporation, with ISO-certified and FDA-approved manufacturing and distribution facilities throughout the globe and headquartered in Southern California. A vast network of global distributors and satellite facilities and offices throughout Europe, Asia, Australia and the Americas assures customers top quality products delivered when and where needed. No matter how dynamic the evolution of the life science and biotechnology markets, we remain committed to supporting our customers in their efforts to make new discoveries. From basic research, through scale-up, to full-scale production and diagnostic testing, MP Biomedicals serves every industry need – from specialized areas of research to supplying large scale quantities of fine chemicals. Our customers partner with us because they want a long-time player and reliable colleague in the fields of life science research and diagnostics. MP Biomedicals will never rest in our odyssey to remain at the forefront of discovery in the ever-changing biomedical industry.

1381 Kinnear Road Columbus, OH, 43212 United StatesWe provide RNA nanoparticles, customized RNA oligoes and modified RNA oligonucleotides as research reagent for research use. We are the only one in the world to supply high-quality RNA nanoparticles as a commercial product for pre-clinical use. Our team has experienced scientists to efficiently coordinate a multidisciplinary effort to transit bio-nanotechnology, especially RNA nanotechnology from the bench to the clinic. RNA nanotechnology allows integration of multiple functional RNA modules into on nanoparticle, of which the scaffold, ligand, therapeutic molecule, and regulator can be composed mainly of RNA. We research and develop a broad range of innovative products in the primary area of RNA nanotechnology based platform for next generation targeted drug delivery and disease diagnosis.

1275 Kinnear Road Columbus, OH, 43212 United StatesWe provide RNA nanoparticles, customized RNA oligoes and modified RNA oligonucleotides as research reagent for research use. We are the only one in the world to supply high-quality RNA nanoparticles as a commercial product for pre-clinical use. Our team has experienced scientists to efficiently coordinate a multidisciplinary effort to transit bio-nanotechnology, especially RNA nanotechnology from the bench to the clinic. RNA nanotechnology allows integration of multiple functional RNA modules into on nanoparticle, of which the scaffold, ligand, therapeutic molecule, and regulator can be composed mainly of RNA. We research and develop a broad range of innovative products in the primary area of RNA nanotechnology based platform for next generation targeted drug delivery and disease diagnosis.

1275 Kinnear Rd Suite 284 Columbus, OH, 43212 United StatesWe provide RNA nanoparticles, customized RNA oligoes and modified RNA oligonucleotides as research reagent for research use. We are the only one in the world to supply high-quality RNA nanoparticles as a commercial product for pre-clinical use. Our team has experienced scientists to efficiently coordinate a multidisciplinary effort to transit bio-nanotechnology, especially RNA nanotechnology from the bench to the clinic. RNA nanotechnology allows integration of multiple functional RNA modules into on nanoparticle, of which the scaffold, ligand, therapeutic molecule, and regulator can be composed mainly of RNA. We research and develop a broad range of innovative products in the primary area of RNA nanotechnology based platform for next generation targeted drug delivery and disease diagnosis.

Unit 1702-1705New Brunswick Scientific offers optimization, cell expertise, computer-controlled strategies, and media formulation.

700 Children's DriveNationwide Children's Hospital's research Institute is one of the nation's ten largest free-standing pediatric research centers and works to enhance the health of children by engaging in high-quality, cutting-edge research.

580 N. 4th Street Suite 270 Columbus, OH USA 43215Novella Clinical offers clinical research resourcing in investigator recruitment and phase I-IV clinical monitoring, data management, pharmacovigilance, and regulatory consultation services.

4209 St. Rt. 44, PO Box 95 Rootstown, Ohio 44272The Comparative Medicine Unit (CMU) is a centralized 41,000-square-foot secured facility located on the University campus. It provides animal care services in support of the research and teaching programs at Northeast Ohio Medical University. The facility can accommodate a broad range of laboratory animal species in a safe and secure environment. A disaster plan has been developed to assure appropriate animal care during emergencies. The institution has an Animal Welfare Assurance on file with the Office of Laboratory Animal Welfare (OLAW) and is registered as a research facility with the United States Department of Agriculture (USDA). The CMU participates in the highly regarded voluntary accreditation program offered by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International. The CMU has been fully accredited by AAALAC since 1982. The CMU was again awarded Continued FULL accreditation status by AAALAC, International on June 9, 2014. Mission Statement The mission of the CMU is to provide the highest standards of animal care and related services in keeping with the Animal Welfare Act regulations, the Public Health Service Policy on Humane Care and Use of Laboratory Animals, the National Research Council’s Guide for the Care and Use of Laboratory Animals, and commonly accepted principles of humane animal care and use. Each member of the CMU staff adheres to these standards in support of the research and teaching missions of Northeast Ohio Medical University and its consortium-related institutions: by delivering CMU services using a cooperative, collegial and professional team approach; with due consideration for animal welfare and research and teaching integrity; and with an ongoing commitment to continuing education.

4209 St. Rt. 44, PO Box 95 Rootstown, Ohio, 44272 United StatesThe Comparative Medicine Unit (CMU) is a centralized 41,000-square-foot secured facility located on the University campus. It provides animal care services in support of the research and teaching programs at Northeast Ohio Medical University. The facility can accommodate a broad range of laboratory animal species in a safe and secure environment. A disaster plan has been developed to assure appropriate animal care during emergencies. The institution has an Animal Welfare Assurance on file with the Office of Laboratory Animal Welfare (OLAW) and is registered as a research facility with the United States Department of Agriculture (USDA). The CMU participates in the highly regarded voluntary accreditation program offered by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International. The CMU has been fully accredited by AAALAC since 1982. The CMU was again awarded Continued FULL accreditation status by AAALAC, International on June 9, 2014. Mission Statement The mission of the CMU is to provide the highest standards of animal care and related services in keeping with the Animal Welfare Act regulations, the Public Health Service Policy on Humane Care and Use of Laboratory Animals, the National Research Council’s Guide for the Care and Use of Laboratory Animals, and commonly accepted principles of humane animal care and use. Each member of the CMU staff adheres to these standards in support of the research and teaching missions of Northeast Ohio Medical University and its consortium-related institutions: by delivering CMU services using a cooperative, collegial and professional team approach; with due consideration for animal welfare and research and teaching integrity; and with an ongoing commitment to continuing education.

4209 St. Rt. 44, PO Box 95 Rootstown, Ohio 44272The Viral Core facility of the Department of Integrative Medical Sciences is an important biotechnological and knowledge resource for the Department’s investigators and their collaborators who request assistance in the use of viral gene expression vectors. The primary function of the core is to construct and purify viral vectors for basic research studies in tissue culture and animal experimentation. The services provided by the core facility include construction of new adenovirus vectors, large scale purification, quantification of adenovirus gene vectors and long term storage. The facility will also assist in bacterial cell transformation, plasmid isolation and large scale purification if needed. Quality control performed by the Viral Core will determine the accurate quantity (plaque assay when available) and purity of the vector generated. Some sequencing assistance of the final virus gene constructs can be provided by the facility’s ability to outsource to a reliable sequencing service. Although the Viral Core facility is limited to adenovirus constructs at this time, expansion of the core’s ability to use adeno-associated viruses, retroviruses and retroviral lentiviruses may occur depending upon the need of our investigators. The core facility will assist the investigator in biosafety issues and requirements of the Northeast Ohio Medical University (NEOMED) Institutional Biosafety Committee for review of their proposed work. The core facility is also available for consultation on experiments requiring gene transfer and expression.

4209 St. Rt. 44, PO Box 95 Rootstown, OH, 44272 United StatesThe Viral Core facility of the Department of Integrative Medical Sciences is an important biotechnological and knowledge resource for the Department’s investigators and their collaborators who request assistance in the use of viral gene expression vectors. The primary function of the core is to construct and purify viral vectors for basic research studies in tissue culture and animal experimentation. The services provided by the core facility include construction of new adenovirus vectors, large scale purification, quantification of adenovirus gene vectors and long term storage. The facility will also assist in bacterial cell transformation, plasmid isolation and large scale purification if needed. Quality control performed by the Viral Core will determine the accurate quantity (plaque assay when available) and purity of the vector generated. Some sequencing assistance of the final virus gene constructs can be provided by the facility’s ability to outsource to a reliable sequencing service. Although the Viral Core facility is limited to adenovirus constructs at this time, expansion of the core’s ability to use adeno-associated viruses, retroviruses and retroviral lentiviruses may occur depending upon the need of our investigators. The core facility will assist the investigator in biosafety issues and requirements of the Northeast Ohio Medical University (NEOMED) Institutional Biosafety Committee for review of their proposed work. The core facility is also available for consultation on experiments requiring gene transfer and expression.

4209 St. Rt. 44, PO Box 95 Rootstown, Ohio 44272The Department of Integrative Medical Sciences offers an Echo Core Laboratory well equipped with the latest technology available for any small animal study that requires echocardiographic assessment. Investigators have access to state-of-the-art instruments, including the VisualSonics Vevo 770 micro-imaging system, capable of delivering the highest quality 2-D ultrasound images, contrast imaging, tissue Doppler and Doppler blood flow. Also in our facility is the Siemens Sequoia system used for perfusion imaging. Our machines, complete with versatile software packages, allow for easy image acquisition and assist investigators in developing customized protocols for imaging of various organ systems. Our facility is also equipped with other useful instruments such as pressure transducer catheters (Millar) and data acquisition systems (ADInstruments) that make other hemodynamic assessments, such as pressure/volume measurements possible. Several current studies being conducted in our facility include structural/functional studies following myocardial infarction, ischemia/reperfusion models and myocardial perfusion (contrast) imaging. Also located within our echo facility are surgical platforms and dissecting microscopes to facilitate the use of the applications.

4209 St. Rt. 44, PO Box 95 Rootstown, OH, 44272 United StatesThe Department of Integrative Medical Sciences offers an Echo Core Laboratory well equipped with the latest technology available for any small animal study that requires echocardiographic assessment. Investigators have access to state-of-the-art instruments, including the VisualSonics Vevo 770 micro-imaging system, capable of delivering the highest quality 2-D ultrasound images, contrast imaging, tissue Doppler and Doppler blood flow. Also in our facility is the Siemens Sequoia system used for perfusion imaging. Our machines, complete with versatile software packages, allow for easy image acquisition and assist investigators in developing customized protocols for imaging of various organ systems. Our facility is also equipped with other useful instruments such as pressure transducer catheters (Millar) and data acquisition systems (ADInstruments) that make other hemodynamic assessments, such as pressure/volume measurements possible. Several current studies being conducted in our facility include structural/functional studies following myocardial infarction, ischemia/reperfusion models and myocardial perfusion (contrast) imaging. Also located within our echo facility are surgical platforms and dissecting microscopes to facilitate the use of the applications.

1655 E. 28th StreetNeuroInDx offers microarray experimental design, transcriptome analysis, RNA preparation/labeling/amplification, and flow sorting services.

Columbus, OH United StatesNitAn Biotech offers transgenic animal generation with knock out or over expression, gene delivery viral vectors, recombinant proteins with gene modifications, protein expression, purification and characterization services.

Crystal Glen Office Center, Suite 356Nagase provides resins, enzymes, antibodies, screening, gene expression, and silicone materials.

4209 SR 44., PO Box 95, Rootstown, Ohio 44272NEOMED is a state supported institution of higher education. It's mission, through education, research and service, improves the health, economy and quality of life of the diverse communities of Northeast Ohio.

North Cliff Consultants, Inc. 3747 Warsaw Avenue Cincinnati, Ohio 45205North Cliff Consultants,Inc. was founded in 1986 to provide independent contract testing services for manufacturers and retailers involved in the personal care, over-the-counter, food, fragrance, and household product markets. We operate two facilities in the Greater Cincinnati Metropolitan Area with a total of 25,000 square feet of testing space. Our Clinical Studies group provides safety and efficacy testing of cosmetic and personal care products. The Sensory Studies group provides consumer testing of all types of food and beverage products, home air freshener products and household products.

4251 Lyons Rd. Miamisburg, OH 45342At NicQuid®, we make fantastic e-liquid. Period. Great care and artistry is a part of our flavor creation process. Our team of experts spend months testing each flavor and hand select each high quality ingredient. We allow for extensive steep (saturation over time) variances, before taking a new creation forward for final review and acceptance to our eliquid line, as well as many other rigorous tests. Our mission is to deliver a product that is unrivaled in the marketplace, with unmatched quality and flavor, and to obtain and maintain the highest level of industry standards. We are one of the only elqiuid companies that completely manufactures all of our eliquid in an ISO Class 7 / FED STD 209E Class 10,000 Clean Room. We have achieved and produced a four collection line of eliquid that tastes as delicious on day thirty as it did on day one, while still delivering the full-bodied vape and throat hit you love. We will not rush numerous new flavors to market just to increase our catalog. Every offering is hand crafted to meet our (and your) exceedingly high standards. NicQuid® places special emphasis on making exciting, bold, and flavorful e-liquid creations, we put an equal amount of care and consideration into the components and facility used in delivering a product that is pure, clean and secure - expenses that will never be spared. Rest assured that when you purchase a NicQuid® e-liquid, you are getting the best. Simply put, e-liquid is our passion. NicQuid® is also a proud founding memeber of AEMSA - "The first and only Manufacturers' trade association completely dedicated to creating responsible and sustainable standards for the safe manufacturing of "e-liquids" used in electronic cigarettes. AEMSA is an all-volunteer organization, formed by American manufacturers of e-liquids, to promote safety and responsibility through self-regulation." AEMSA Mission: "We readily acknowledge and respect that liquid nicotine can be an ingredient of concern and, as such, requires responsible and professional handling and distribution. We also acknowledge and respect the other three ingredients are available in various categories in their individual quality and application. Further, we acknowledge and respect the entire process of handling and combining these ingredients, for consumption by consumers, deserves professionalism. AEMSA Standards demand high quality ingredients and accuracy in content.

4251 Lyons Rd. Miamisburg, , OH , 45342 United StatesAt NicQuid®, we make fantastic e-liquid. Period. Great care and artistry is a part of our flavor creation process. Our team of experts spend months testing each flavor and hand select each high quality ingredient. We allow for extensive steep (saturation over time) variances, before taking a new creation forward for final review and acceptance to our eliquid line, as well as many other rigorous tests. Our mission is to deliver a product that is unrivaled in the marketplace, with unmatched quality and flavor, and to obtain and maintain the highest level of industry standards. We are one of the only elqiuid companies that completely manufactures all of our eliquid in an ISO Class 7 / FED STD 209E Class 10,000 Clean Room. We have achieved and produced a four collection line of eliquid that tastes as delicious on day thirty as it did on day one, while still delivering the full-bodied vape and throat hit you love. We will not rush numerous new flavors to market just to increase our catalog. Every offering is hand crafted to meet our (and your) exceedingly high standards. NicQuid® places special emphasis on making exciting, bold, and flavorful e-liquid creations, we put an equal amount of care and consideration into the components and facility used in delivering a product that is pure, clean and secure - expenses that will never be spared. Rest assured that when you purchase a NicQuid® e-liquid, you are getting the best. Simply put, e-liquid is our passion. NicQuid® is also a proud founding memeber of AEMSA - "The first and only Manufacturers' trade association completely dedicated to creating responsible and sustainable standards for the safe manufacturing of "e-liquids" used in electronic cigarettes. AEMSA is an all-volunteer organization, formed by American manufacturers of e-liquids, to promote safety and responsibility through self-regulation." AEMSA Mission: "We readily acknowledge and respect that liquid nicotine can be an ingredient of concern and, as such, requires responsible and professional handling and distribution. We also acknowledge and respect the other three ingredients are available in various categories in their individual quality and application. Further, we acknowledge and respect the entire process of handling and combining these ingredients, for consumption by consumers, deserves professionalism. AEMSA Standards demand high quality ingredients and accuracy in content.

11000 Cedar Ave. Cleveland, OH 44106 USANeo Proteomics offer a wide range of mass spectrometry, biophysics, and structural biology services including: peptide mapping, epitope mapping, glycosylation analysis, PTM analysis, quantitative proteomic and phosphoproteomics, structural mass spectrometry, crystallization trials, synchrotron data collection and structural solution. Epitope Mapping and Protein-Drug binding: Neo specializes in advanced epitope mapping and protein structure assessment using covalent-labeling mass spectrometry (CL-MS). These approaches can establish IP protection for novel biotechnology products as well as define structure parameters important for regulatory filings in the case of both innovator and biosimilars products. CL-MS precisely defines drug and epitope binding sites and provides detailed structural characterization of protein-drug complexes. Specifically CL-MS (often called protein footprinting) provides a high resolution and sensitive readout of the amino acid side chain environment (e.g. solvent accessibility) for virtually all amino acids in a protein of interest. Crystallography: Neo has advanced capabilities for macromolecular crystallography services at advanced synchrotron sources. Services from crystallization trials to data collection to structural solution are available including rapid turnaround.

11000 Cedar Ave United States Cleveland, Ohio, 44106-4988 United StatesNeo Proteomics offer a wide range of mass spectrometry, biophysics, and structural biology services including: peptide mapping, epitope mapping, glycosylation analysis, PTM analysis, quantitative proteomic and phosphoproteomics, structural mass spectrometry, crystallization trials, synchrotron data collection and structural solution. Epitope Mapping and Protein-Drug binding: Neo specializes in advanced epitope mapping and protein structure assessment using covalent-labeling mass spectrometry (CL-MS). These approaches can establish IP protection for novel biotechnology products as well as define structure parameters important for regulatory filings in the case of both innovator and biosimilars products. CL-MS precisely defines drug and epitope binding sites and provides detailed structural characterization of protein-drug complexes. Specifically CL-MS (often called protein footprinting) provides a high resolution and sensitive readout of the amino acid side chain environment (e.g. solvent accessibility) for virtually all amino acids in a protein of interest. Crystallography: Neo has advanced capabilities for macromolecular crystallography services at advanced synchrotron sources. Services from crystallization trials to data collection to structural solution are available including rapid turnaround.

4450 Cranwood ParkwayNSL Analytical Services offers inorganic trace element analysis, microscopy evaulation, polymer, purity and composite testing services.

6750 Wales Road Northwood, OH, 43619 United StatesNAMSA is a Medical Research Organization (MRO), accelerating product development through integrated laboratory, clinical and consulting services. Driven by our regulatory expertise, NAMSA’s MRO® Approach plays an important role in translational research, applying a unique combination of disciplines—consulting, preclinical, toxicology, microbiology, chemistry, clinical and quality—to move client’s products through the development process, and continue to provide support through commercialization to post-market requirements, anywhere in the world.

9100 S Hills Blvd #300 Broadview Heights, OH, 44147 United StatesNelson Labs®, a Sotera Health company, is an industry-leading, global provider of laboratory testing and expert advisory services. We perform over 800 rigorous microbiological and analytical laboratory tests across the medical device, pharmaceutical, protective barriers, and tissue industries. We know that every test matters and requires solutions to complex problems to improve patient outcomes and minimize client risk. We are a business unit of Sotera Health (Nasdaq: SHC), along with Nordion® and Sterigenics®. Together we are a leading global provider of mission-critical sterilization and lab-testing and advisory services for the healthcare industry and touch the lives of more than 190 million people around the world each year.

9100 S Hills Blvd #300 Broadview Heights, OH, 44147 United StatesNelson Labs®, a Sotera Health company, is an industry-leading, global provider of laboratory testing and expert advisory services. We perform over 800 rigorous microbiological and analytical laboratory tests across the medical device, pharmaceutical, protective barriers, and tissue industries. We know that every test matters and requires solutions to complex problems to improve patient outcomes and minimize client risk. We are a business unit of Sotera Health (Nasdaq: SHC), along with Nordion® and Sterigenics®. Together we are a leading global provider of mission-critical sterilization and lab-testing and advisory services for the healthcare industry and touch the lives of more than 190 million people around the world each year.

27070 Miles RoadOakwood Laboratories offers API products and manufacturing services.

7670 First Place Suite A Oakwood Village, OH, 44146-6714 United StatesOakwood Laboratories offers API products and manufacturing services.

710-223 Jackson ST WOlinax offers bulk APIs, intermediates, fine chemicals, stable isotopes, and PEGylation services.

110 Arps HallOhio State University College of Education and Human Ecology focuses on research.

1305 Kinnear Rd Suite 100 Columbus, OH 43212CEMAS is one of the largest concentrations of electron and ion beam analytical microscopy instruments in any North American institution. This includes two aberration corrected scanning transmission electron microscopes (S/TEM). One instrument is optimized for high spatial resolution imaging and analysis with the capability to provide sub-angstrom resolution, while the second instrument is designed for investigation of soft materials and biomaterials with the ultimate in chemical analysis capabilities as well as high resolution imaging performance. CEMAS is housed in a custom-designed environment located on West Campus. This facility provides a world-class environment for five transmission electron microscopes (TEM), three scanning electron microscopes (SEM) and two dual-beam focused ion beam (FIB) instruments. Sample preparation laboratories for life sciences, physical sciences and engineering are provided with full technical support. The provision of comprehensive computer facilities for data processing and image simulation allows academic and industrial users to carry out their entire microscopy and analysis program at CEMAS. A support team of technical, research, administrative and academic staff based at CEMAS provides comprehensive support to all users through a variety of mechanisms from contract research to collaborative projects. The imaging and analytical facilities are complimented by extensive sample preparation facilities. As well as FIB prep for TEM, there are tools for cutting, grinding, trepanning and ion milling samples. For SEM preparation there are carbon and gold sputter coaters, which can also be used for replica techniques. The preparation equipment covers a wide range of techniques to handle the large variety of samples that are brought into the facility. It is planned to develop procedures for cryo-preparation of samples for soft material and biomaterial applications. We have ambitious plans to expand the facility to include new instrumentation for which we are currently seeking funds, and to extend our capabilities further into soft and biological materials. We have designed the new environment with this in mind, and potentially have space to accommodate up to four aberration corrected instruments.

510 Porter Hall Athens, Ohio 45701The Ohio University Genomics Facility was established in 2007 by funds secured through a NSF award to Drs. Sarah Wyatt & Morgan Vis for major instrumentation. The Ohio University Genomics Facility has been instrumental in increasing the researcher’s potential by providing services like DNA sequencing, fragment analysis, RNA, DNA, protein and cell cytometry services through various equipment. Various new equipment and software have been added since 2007. All the data generated by the Genomics Facility has furthered the research of many students, postdoctoral fellows/technicians and PI’s working in different areas of science at Ohio University. The facility has also been instrumental in implementing teaching modules and a laboratory techniques course in the area of genomics to various programs like Biomedical Engineering, Forensic Science, and Cell and Molecular Biology. Apart from this, the Genomics Facility director provides tours, lectures and out reach activities to train undergraduate and graduate students. The facility has served as an important educational focal point for genomics science. With the increasing importance of genomics in various sciences, the Ohio University Genomics Facility has been a meeting place for various disciplines like Chemical Engineering, Civil Engineering, Biology, Chemistry and Biochemistry, Forensic Science, Psychology, Computer Science and Medical Sciences. The facility has been extensively supported by the OU researchers, Office of Vice President for Research, College of Arts & Sciences and Dept of Environmental and Plant biology

510 Porter Hall Anthens, Ohio, 45701 United StatesThe Ohio University Genomics Facility was established in 2007 by funds secured through a NSF award to Drs. Sarah Wyatt & Morgan Vis for major instrumentation. The Ohio University Genomics Facility has been instrumental in increasing the researcher’s potential by providing services like DNA sequencing, fragment analysis, RNA, DNA, protein and cell cytometry services through various equipment. Various new equipment and software have been added since 2007. All the data generated by the Genomics Facility has furthered the research of many students, postdoctoral fellows/technicians and PI’s working in different areas of science at Ohio University. The facility has also been instrumental in implementing teaching modules and a laboratory techniques course in the area of genomics to various programs like Biomedical Engineering, Forensic Science, and Cell and Molecular Biology. Apart from this, the Genomics Facility director provides tours, lectures and out reach activities to train undergraduate and graduate students. The facility has served as an important educational focal point for genomics science. With the increasing importance of genomics in various sciences, the Ohio University Genomics Facility has been a meeting place for various disciplines like Chemical Engineering, Civil Engineering, Biology, Chemistry and Biochemistry, Forensic Science, Psychology, Computer Science and Medical Sciences. The facility has been extensively supported by the OU researchers, Office of Vice President for Research, College of Arts & Sciences and Dept of Environmental and Plant biology

195 W Olentangy St Suite O Powell, OH, 43065 United StatesOhio Peptide offers custom peptide synthesis and catalog peptides.

Radar Hill Trail Athens, OH, 45701 United StatesSamples are collected by clinical research nurses from patients who agreed to participate in the biorepository and samples are coded with their UMA chart number. Whole blood is transported by Biorepository personnel from UMA to the Biorepository at the Edison Biotechnology Institute. Upon arrival at the Biorepository, samples are bar coded to protect patient identity, entered into a commercial inventory database (Freezerworks® by Dataworks Development), and immediately processed.

420 West 12th Avenue Columbus, OH, 43210 United StatesThe Leukemia Tissue Bank Shared Resource (LTBSR) helps scientists translate basic research to the clinical setting by providing central collection, processing and storage of tissue samples from patients with leukemia, myeloma or lymphoma enrolled on Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James) protocols. These samples are available to investigators at Ohio State and to outside collaborators who study the cellular and molecular properties of these diseases. The ability to examine tumor cells from patients is an essential part of determining the causes of cancer and developing new and effective treatments.

460 W. 12th Ave. 2nd Floor BRT283 Biomedical Research Tower Columbus, OH, USAOhio State University Nucleic Acid Shared Resource (NASR) provides instrumentation and expertise for DNA sequencing, genotyping, real-time PCR, RNA/DNA extraction, imaging and DNA synthesis support.

1082 Biomedical Research TowerOhio State University Human Cancer Genetics Program focuses on gene discovery, epigenetics, genomics, and proteomics research.

236 Irvine Hall Athens, OH 45701Our mission is to provide the best possible environment for clinical research – one that fosters the creation of new knowledge in health care and protects the safety and well-being of study participants who put their trust in our hands. Our vision is to be nationally recognized as one of the leading clinical trial facilities associated with a medical school. We operate under the guiding principles of respect for all people, unwavering adherence to the highest ethical standards and a deep sense of interdisciplinary collaboration to further the advancement of healthcare.

236 Irvine Hall Anthens, OH, 45701 United StatesOur mission is to provide the best possible environment for clinical research – one that fosters the creation of new knowledge in health care and protects the safety and well-being of study participants who put their trust in our hands. Our vision is to be nationally recognized as one of the leading clinical trial facilities associated with a medical school. We operate under the guiding principles of respect for all people, unwavering adherence to the highest ethical standards and a deep sense of interdisciplinary collaboration to further the advancement of healthcare.

525 SOUTH MAIN STREET ADA, OH 45810Ohio Northern University is an independent, comprehensive University located in the scenic village of Ada, Ohio. The University comprises five colleges: Arts & Sciences, Business Administration, Engineering, Pharmacy and Law. Since our inception in 1871, we’ve been devoted to developing students who are ready to immerse themselves and progress to the next level
 in everything they do. ONU has a rich history of academic excellence, and we’re always evolving to meet society’s ever-changing needs. We’ve most recently been recognized for teaching quality, high graduation rates, commitment to volunteer service and, most impressively, providing a high return on investment for our graduates.

525 SOUTH MAIN STREET ADA, , OH , 45810 United StatesOhio Northern University is an independent, comprehensive University located in the scenic village of Ada, Ohio. The University comprises five colleges: Arts & Sciences, Business Administration, Engineering, Pharmacy and Law. Since our inception in 1871, we’ve been devoted to developing students who are ready to immerse themselves and progress to the next level
 in everything they do. ONU has a rich history of academic excellence, and we’re always evolving to meet society’s ever-changing needs. We’ve most recently been recognized for teaching quality, high graduation rates, commitment to volunteer service and, most impressively, providing a high return on investment for our graduates.

101 N. Professor St., Oberlin, OH 44074The College of Arts and Sciences offers a rich and balanced curriculum in the humanities, social sciences, and natural sciences. We welcome young passionate intellectuals who are eager to help make the local community and the world a better place.

101 N. Professor St., Oberlin , OH , 44074 United StatesThe College of Arts and Sciences offers a rich and balanced curriculum in the humanities, social sciences, and natural sciences. We welcome young passionate intellectuals who are eager to help make the local community and the world a better place.

E337 Scott Laboratory 201 West 19th Avenue Columbus, Ohio 43210The Trace Element Research Laboratory (TERL) has world-class capabilities for elemental chemical measurements for an incredibly wide variety of applications in earth, environmental, chemical, biological, medical and materials sciences. Superb expertise and state of the art inductively coupled plasma based optical emission and mass spectrometry instruments are available. Most of the elements in the periodic table (other than C, N, O, F and noble gas elements) can be measured at concentrations from major (%) to ultratrace (part per trillion). Measurements can be made on solution samples, solids following digestion or, using laser ablation sampling, directly on solids. Available Instrumentation Inductively Coupled Plasma Optical Emission Spectrometers (ICP-OES) for elemental analysis of solutions (to ng/mL) or solids following dissolution PerkinElmer Optima 3000DV ICP-OES PerkinElmer Optima 4300DV ICP-OES Inductively Coupled Plasma Mass Spectrometer (ICP-MS) for elemental analysis of solutions (to pg/mL concentrations), solids following dissolution, or solids sampled by laser ablation (4 to 200 um spot size) and then carried into the ICP-MS in a flowing AR gas PerkinElmer Sciex ELAN 6000 ICP-MS PerkinElmer Sciex ELAN 6100 DRCplus ICP-MS with Dynamic Reaction Cell ThermoFinnigan Element 2 ICP-Sector Field MS New Wave Research UP-193 Laser Ablation with beam homogenized 193 nm laser

E337 Scott Laboratory 201 West 19th Avenue Columbus, OH, 43210 United StatesThe Trace Element Research Laboratory (TERL) has world-class capabilities for elemental chemical measurements for an incredibly wide variety of applications in earth, environmental, chemical, biological, medical and materials sciences. Superb expertise and state of the art inductively coupled plasma based optical emission and mass spectrometry instruments are available. Most of the elements in the periodic table (other than C, N, O, F and noble gas elements) can be measured at concentrations from major (%) to ultratrace (part per trillion). Measurements can be made on solution samples, solids following digestion or, using laser ablation sampling, directly on solids. Available Instrumentation Inductively Coupled Plasma Optical Emission Spectrometers (ICP-OES) for elemental analysis of solutions (to ng/mL) or solids following dissolution PerkinElmer Optima 3000DV ICP-OES PerkinElmer Optima 4300DV ICP-OES Inductively Coupled Plasma Mass Spectrometer (ICP-MS) for elemental analysis of solutions (to pg/mL concentrations), solids following dissolution, or solids sampled by laser ablation (4 to 200 um spot size) and then carried into the ICP-MS in a flowing AR gas PerkinElmer Sciex ELAN 6000 ICP-MS PerkinElmer Sciex ELAN 6100 DRCplus ICP-MS with Dynamic Reaction Cell ThermoFinnigan Element 2 ICP-Sector Field MS New Wave Research UP-193 Laser Ablation with beam homogenized 193 nm laser

526 South Main Street United States Akron, OH, 44311 United StatesOur high-throughput and robust technology uses a robotic platform and aqueous polymeric system to generate biologically relevant 3D tumor models. These tumor models can be conveniently maintained, drug tested, and analyzed in the microplate they are formed. Our novel aqueous polymeric system ensures the rapid (within 2 days) formation of a single consistently-sized 3D culture per microplate well for precise analysis of drug response. We provide cancer drug screening services on biologically relevant tumor models generated with our technology in 96-,384-, and 1536- microplate formats.

526 S. Main Street, Suite 818 United States Akron, OH, 44311 United StatesOur high-throughput and robust technology uses a robotic platform and aqueous polymeric system to generate biologically relevant 3D tumor models. These tumor models can be conveniently maintained, drug tested, and analyzed in the microplate they are formed. Our novel aqueous polymeric system ensures the rapid (within 2 days) formation of a single consistently-sized 3D culture per microplate well for precise analysis of drug response. We provide cancer drug screening services on biologically relevant tumor models generated with our technology in 96-,384-, and 1536- microplate formats.

1244 James Cancer HospitalOhio State University Comprehensive Cancer Center Molecular Cytogenetics Shared Resource provides tissue culture, fluorescence in situ hybridization, and spectral karyotyping services.

Columbus, OH United StatesOhio State University Comprehensive Cancer Center Molecular Cytogenetics Shared Resource provides tissue culture, fluorescence in situ hybridization, and spectral karyotyping services.

484 West 12th Avenue Columbus, OH, 43210 United States

Biomedical Research Tower 460 W. 12th Ave. Room 250 Columbus, OH 43210

4293 Mulhauser Rd, Fairfield, OH 45014Orchem Corporation is the leading minority-owned specialty chemical manufacturer in the United States, with extensive expertise in proprietary product formulation, contract manufacturing and distribution services while also providing cleaning and sanitizing solutions to the food, beverage, dairy processing, institutional, healthcare, general industrial, residential, and commercial markets. Orchem manufactures a wide range of hard surface cleaners and sanitizers, laundry detergents, and industrial process chemicals, incorporating the latest blends of surfactant and synthetic chemistry. Additionally, Orchem is capable of providing full turnkey private label manufacturing, distribution, and market support to entrepreneurial candidates looking for an opportunity to start their own business.

526 S. Main Street Akron OH 44311 USAPolyInsight offers validation tests, certification, and determination of material structure.

1476 Manning Parkway Powell, Ohio, 43065 United StatesPhylogeny provides histology and functional genomic services including ISH and FISH. Our scientists specialize in working with you to design cost effective in situ hybridizations to help you answer your most complicated gene expression questions.

8921 Brecksville Rd.,PharmaZell provides APIs, intermediates, custom synthesis, analytical and regulatory services, and pharmaceutical development.

530 University Ave, Mail Box # 203PrognosDX Health focuses on developing novel, semi-quantitative and quantitative laboratory products based on global histone modification patterns.

Columbus, OH United StatesPrologue Research offers clinical research services such as phase I-IV clinical trial management, site monitoring, pharmacovigilance, data management, biostatistics, regulatory compliance and quality assurance.

Sharon Woods Innovation Center 11530 Reed Hartman Highway Cincinnati, OH 45241Our purpose is to deliver solutions and create value for our customers and suppliers, both internally to P&G and externally. We have a long history of investing and operating in the oleochemicals industry, going back to the early 1800s when P&G began using stearic acid in its candles and re-selling olein (red oil) as a co-product. Since 1837 we have taken a comprehensive approach to the business, focusing on delivering these key points of difference.

Sharon Woods Innovation Center 11530 Reed Hartman Highway Cincinnati, 45241 United StatesOur purpose is to deliver solutions and create value for our customers and suppliers, both internally to P&G and externally. We have a long history of investing and operating in the oleochemicals industry, going back to the early 1800s when P&G began using stearic acid in its candles and re-selling olein (red oil) as a co-product. Since 1837 we have taken a comprehensive approach to the business, focusing on delivering these key points of difference.

44 Denver RoadPrecision Medical Products manufactures and packages medical devices to support medical, surgical, dental, and pharmaceutical product applications.

3182 Beekman Street Cincinnati, OH 45242 USAProteios offers raw materials production, protein purification, protein characterization, assay development, and conjugation services.

Cincinnati, OH United StatesProteios offers raw materials production, protein purification, protein characterization, assay development, and conjugation services.

1946 North 13th Street, Suite 301 Toledo, Ohio 43604Established in Toledo, Ohio in 1946, Pathology Laboratories, Inc. (PathLabs) fostered a reputation among the area's private medical practitioners as a provider of prompt, reliable and convenient laboratory testing services. Its status as a key partner in the delivery of quality medical care to the community was advanced in 1970 when PathLabs became the first independent medical laboratory in Ohio to seek and attain accreditation by the College of American Pathologists - the preeminent laboratory certifying body in the nation. Over the ensuing decades, PathLabs continued its tradition of uncompromising quality, personal service and overall excellence to become the dominant full-service independent medical laboratory in northwest Ohio and southeast Michigan. Since 2004, we have rapidly expanded our operations to other areas of Ohio including Cleveland, Columbus and Lima and their surrounding communities. Committed to a formal yet dynamic quality assurance program, PathLabs regularly monitors key quality indicators. Significant variations from established performance thresholds are examined and corrective measures implemented, as needed. An extensive regulatory compliance program and compliance review committee have also been formed to assure PathLabs' conformity with all applicable federal, state and local laws and guidelines governing the laboratory industry. PathLabs employs a contingent of 200+ well-trained personnel working in various administrative, managerial, technical, marketing and support positions. A professional group, consisting of six (6) pathologists, is contracted to provide anatomic and clinical pathology services and medical directorship in all markets currently serviced by PathLabs. Members of the group are also available 24 hours a day for physician consultation.

1946 North 13th Street, Suite 301 Toledo, OH, 43604 United StatesEstablished in Toledo, Ohio in 1946, Pathology Laboratories, Inc. (PathLabs) fostered a reputation among the area's private medical practitioners as a provider of prompt, reliable and convenient laboratory testing services. Its status as a key partner in the delivery of quality medical care to the community was advanced in 1970 when PathLabs became the first independent medical laboratory in Ohio to seek and attain accreditation by the College of American Pathologists - the preeminent laboratory certifying body in the nation. Over the ensuing decades, PathLabs continued its tradition of uncompromising quality, personal service and overall excellence to become the dominant full-service independent medical laboratory in northwest Ohio and southeast Michigan. Since 2004, we have rapidly expanded our operations to other areas of Ohio including Cleveland, Columbus and Lima and their surrounding communities. Committed to a formal yet dynamic quality assurance program, PathLabs regularly monitors key quality indicators. Significant variations from established performance thresholds are examined and corrective measures implemented, as needed. An extensive regulatory compliance program and compliance review committee have also been formed to assure PathLabs' conformity with all applicable federal, state and local laws and guidelines governing the laboratory industry. PathLabs employs a contingent of 200+ well-trained personnel working in various administrative, managerial, technical, marketing and support positions. A professional group, consisting of six (6) pathologists, is contracted to provide anatomic and clinical pathology services and medical directorship in all markets currently serviced by PathLabs. Members of the group are also available 24 hours a day for physician consultation.

622 Main Street Genoa,Ohio 43430Pearson & Pearson works with multiple flavor development companies from across the US. After 16 years of industry knowledge we can quickly brief the development companies on our clients concept, ideas and goals. This allows us to secure a US approved formula that is shelf stable and ready of the market.

Room 1406 & 1407, 14F, Tower AParexel provides bioequivalence studies as well as clinical services across Phase I to Phase III of drug development including dose escalation, drug-drug interaction, biomarkers, first-in-man studies, ADME, imaging, and clinical research services.

2110 East Galbraith Road Cincinnati, OH 45237-1625 USAPatheon is the leading publicly listed provider of drug development and manufacturing services to global pharmaceutical, biotechnology and specialty pharmaceutical companies.

3 Innovation Way, Suite 240QPS provides bioanalytical LC/MS/MS services, immunoanalytical services, biomarker discovery services, and in vitro and in vivo ADME services.

1700 Highland Road Twinsburg, Ohio 44087Qure Medical’s expertise lies in providing medical components requiring the highest levels of quality and process repeatability for a blue-chip customer base consisting of more than 20 of the top 30 medical device companies. Uniquely positioned with key locations across the globe, Qure offers a full suite of products to existing customers and new prospects: Internal compounding and proprietary material formulations FDA-Registered Drug Master Files (DMFs) Unmatched offering of products and processes Polyisoprene, organic and silicone polymers technology LIM, HCR (transfer) and extrusion processing technology Overmolding, subassembly, full assembly and distribution capabilities Vertically integrated to “punch above our weight class” Full-service engineering support, coupled with state-of-the-art manufacturing facilities and global collaboration Expert tooling design assistance, construction and maintenance for high and low volume output Proprietary process technologies, including advanced automation and inspection for more flexibility and control ISO 13485 certification and FDA registered product manufacturing capabilities Class 7 and 8 Cleanroom manufacturing, including facilities in China and the United Kingdom

1700 Highland Road Twinsburg, , Ohio , 44087 United StatesQure Medical’s expertise lies in providing medical components requiring the highest levels of quality and process repeatability for a blue-chip customer base consisting of more than 20 of the top 30 medical device companies. Uniquely positioned with key locations across the globe, Qure offers a full suite of products to existing customers and new prospects: Internal compounding and proprietary material formulations FDA-Registered Drug Master Files (DMFs) Unmatched offering of products and processes Polyisoprene, organic and silicone polymers technology LIM, HCR (transfer) and extrusion processing technology Overmolding, subassembly, full assembly and distribution capabilities Vertically integrated to “punch above our weight class” Full-service engineering support, coupled with state-of-the-art manufacturing facilities and global collaboration Expert tooling design assistance, construction and maintenance for high and low volume output Proprietary process technologies, including advanced automation and inspection for more flexibility and control ISO 13485 certification and FDA registered product manufacturing capabilities Class 7 and 8 Cleanroom manufacturing, including facilities in China and the United Kingdom

1400 Harrison Ave Cincinnati, OH, 45214 United StatesQ Laboratories provides microbiological services, analytical chemistry, and research and development.

6456 Fiesta Drive Columbus OH 43235 USAQTest Labs offers DMPK, pharmacology, and evaluation of therapeutics in mammals. QTest Labs is a CRO that specializes in efficacy, cardiovascular safety, and risk assessment of a pharmaceutical or medical device. Our aim is to minimize lead-time and cardiovascular risk, while increasing mechanistic understanding of the test article or device. We bring state-of-the-art science and technology to establish both drug safety and efficacy in a cost effective, expeditious manner, linking discovery, and pre-clinical trials to make drugs and devices safer for tomorrow. The response of a test article/device is mediated by it's complex interactions with different physiological systems. QTest thoroughly explores these interactions providing a clear and complete understanding of your products affects and liabilities. We utilize a series of models to expand the range of cardiovascular information that can be assessed on test articles. These models also ensure that studies are more comprehensive and economical. Understand your product completely! While others design limited studies based solely on regulatory guidelines and a fixed set of assessment tools, QTest Labs understands that truly predictive efficacy and safety testing must go beyond these constraints. By combining our unique, patent-pending paradigm, world renowned group of scientists, and state-of-the-art facilities, QTest Labs is positioned to offer clients services customized to meet their knowledge needs in a way that no others can. We deliver seamless, cost-effective and accurate results, establishing the safety and efficacy of your test article, helping you better understand your product. Our Scientists include DVM cardiologists, a board certified anesthesiologist specializing in pain, and a biomedical engineer, who have worked for years in cardiovascular physiology, pharmacology, and toxicology and have over 750 publications in peer-reviewed journals. Two board-certified veterinary cardiologists, with experience in drug development and testing, supervise experiments and data analysis. A certified quality assurance officer audits all data for critical studies. Experiments are conducted according to excellent laboratory practices by personnel experienced in cardiovascular physiology (including electrophysiology) and pharmacology. We bring state-of-the-art science and technology to establish both drug safety and efficacy in a cost effective, expeditious manner.

5067 New State Road Plymouth, OH, 44865 United StatesRyerson Chinchilla was formed in 1988 when its founders, Rich and Jan Ryerson purchased their first chinchilla's. After several yearsof growth we started to make our own cages and cage supplies. Also we were buying in truckload quanities, Traditional Chinchilla Feed, pine shavings Hidden Valley Hay cubes, Blue Cloud and Blue Sparkle dust bath. Now Ryerson Chinchilla uses the internet for 90% of our supply orders. We now can supply many ranchers throughtout the US with high quality chinchilla supplies at a reasonable cost.

Room 2308-2318Research Pharmaceutical Services offers manufacturing, formulation, regulatory affairs, quality assurance, molecular modeling, and clinical management.

1275 Olentangy River RoadRadiant Research offers phase I-IV clinical research services including project management, quality assurance, biostatistics, and clinical monitoring with expertise in dermatology, endocrinology, infectious disease, and metabolism.

11500 Northlake Drive, Suite 320Radiant Research offers phase I-IV clinical research services including project management, quality assurance, biostatistics, and clinical monitoring with expertise in dermatology, endocrinology, infectious disease, and metabolism.

7528 Auburn Road Concord, OH 44077 USADiscovery and development services to support your drug candidates from lead identification through IND and NDA submission. Capabilities include PK and metabolism screening, medicinal chemistry, IND-enabling toxicology, API process chemistry and cGMP manufacturing and scale-up.

OH United StatesDiscovery and development services to support your drug candidates from lead identification through IND and NDA submission. Capabilities include PK and metabolism screening, medicinal chemistry, IND-enabling toxicology, API process chemistry and cGMP manufacturing and scale-up.

10000 Cedar Avenue Cleveland, OH, 44106 United StatesRenovo Neural offers in vitro cell-based assays, an Augmented Cuprizone mouse models of multiple sclerosis, neurohistology, Immunohistochemistry, digital image analysis, and 3D electron microscopy services.

1038 Jaeger Street Columbus, OH, 43206 United StatesRemo Contract Research Organization (Remo CRO) offers full depth and breadth: preclinical, regulatory, and clinical service capabilities Consultation to strengthen your internal team Laboratory work on an array of preclinical cell and animal models Clinical trials support as needed through trial design, site selection, patient recruitment Sponsors get a customized services with a dedicated partner in Remo CRO Preclinical Service Line: Remo CRO Preclinical Services offers a full line of testing for efficacy and safety of your lead compound. We offer a wide range of experimental and disease models ranging from cell cultures to whole animal models and alternative species modelsWe incorporate bioinformatics with our Preclinical Development programs to identify ideal patient populations and minimize late-stage drug development failure. Our expert team is involved in every stage of your preclinical drug development from advising on experimental design to a comprehensive final report with raw data and full statistical analysis and interpretation. We offer Medical Writing (Clinical Research Protocols, Study Related Documents), Regulatory Document Assessment, Auditing & Compliance Overview, QC, Pharmacovigilance, Biostatistics. PRE-IND: Before initiating time-consuming non-clinical studies and establishing a clinical trial design, discuss plans with the FDA (and EMA) in a pre-IND meeting. Get FDA feedback on proposed IND studies and initial data. Remo CRO can arrange the pre-IND meeting, prepare the documentation package, and guide you to ask the right questions. IND: An IND application requests FDA authorization to administer an investigational drug or biologic to humans. It typically includes structure and composition of the candidate, manufacturing specifications, analytical evaluations, proposed safety studies, and the clinical study design. Remo CRO can ready your entire data and documentation package for an IND submission.

1038 Jaeger ST United States Columbus, Ohio, 43206 United StatesRemo Contract Research Organization (Remo CRO) offers full depth and breadth: preclinical, regulatory, and clinical service capabilities Consultation to strengthen your internal team Laboratory work on an array of preclinical cell and animal models Clinical trials support as needed through trial design, site selection, patient recruitment Sponsors get a customized services with a dedicated partner in Remo CRO Preclinical Service Line: Remo CRO Preclinical Services offers a full line of testing for efficacy and safety of your lead compound. We offer a wide range of experimental and disease models ranging from cell cultures to whole animal models and alternative species modelsWe incorporate bioinformatics with our Preclinical Development programs to identify ideal patient populations and minimize late-stage drug development failure. Our expert team is involved in every stage of your preclinical drug development from advising on experimental design to a comprehensive final report with raw data and full statistical analysis and interpretation. We offer Medical Writing (Clinical Research Protocols, Study Related Documents), Regulatory Document Assessment, Auditing & Compliance Overview, QC, Pharmacovigilance, Biostatistics. PRE-IND: Before initiating time-consuming non-clinical studies and establishing a clinical trial design, discuss plans with the FDA (and EMA) in a pre-IND meeting. Get FDA feedback on proposed IND studies and initial data. Remo CRO can arrange the pre-IND meeting, prepare the documentation package, and guide you to ask the right questions. IND: An IND application requests FDA authorization to administer an investigational drug or biologic to humans. It typically includes structure and composition of the candidate, manufacturing specifications, analytical evaluations, proposed safety studies, and the clinical study design. Remo CRO can ready your entire data and documentation package for an IND submission.

411 Hackensack Ave. Ste.901, 5080 Tuttle Crossing Blvd Suite 400 Dublin, OH, 43016 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

1900 Polaris Parkway Columbus, OH, 43240 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

PO Box 888 Dublin, OH, 43017 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

1390 Neubrecht Rd. Lima, OH, 45801 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

508 Park Place Cincinnati, OH, 45244 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

10999 Reed Hartman Highway Suite 304B Cincinnati, OH, 45242 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

759 Wessel Drive Fairfield, OH, 45014 United StatesWe provide complete clinical services solution for animal health companies developing new animal feed, drug, biologic and medical device products. SAHCRO was formed to exploit the animal health clinical experience of the staff’s of STATKING Consulting, Inc. and Animal Care Centers, Inc. both located in Fairfield, OH. Both staffs had been doing studies with some of the largest animal health companies in the United States. SAHCRO was formed to leverage this experience for small to mid size animal health companies who are seeking outside funding for their product development projects (venture cap funding, foundation funding, crowd funding, government funding, large animal health company funding). SAHCRO staff work with these companies to bring their products to regulatory approval by providing services such as site services, clinical trial management, biostatistics, clinical data management, and clinical study monitoring, all under strict SOPs for process execution. In addition, unlike other CROs, we provide strategic consulting services in statistics, regulatory and veterinary medicine as the product progresses through the regulatory pathway. Our goals for this company are the following: Provide All Deliverables in the Agreed Upon Timelines Provide Quality Work Products and Deliverables Provide Fair and Affordable Pricing for CRO Services

4791 W 150 th St Cleveland, OH, 44135 United StatesWithin a year of its founding in 1989, ScottCare launched its first telemetry system for cardiopulmonary rehabilitation. ScottCare quickly became a market leader by continually improving its telemetry platform. This innovation paved the way for new product development and service in these markets: Cardiopulmonary rehabilitation Diagnostic cardiology Electronic data integration Cardiac monitoring services Our mission to facilitate improved patient care and clinical outcomes while reducing the overall cost of healthcare is accomplished by providing high-quality devices, software, data integration and clinical labor services that aid hospitals and cardiology practices in the diagnosis and management of cardiovascular disease worldwide. ScottCare has been in business for more than a quarter of a century; we are a division of Scott Fetzer, which is a diversified manufacturer and marketer of high-quality products for the home, family and industry comprising more than 20 businesses. You can count on ScottCare to be here today and well into the future to support your continually evolving needs.

P.O. Box 15027 Cincinnati OH 45215 USASolvay/Girindus offers preclinical to phase II services, process research, cGMP pilot plants, and radiosynthesis.

103 Morgan Lane, Suite#104Symphony Pharma Life Sciences offers custom research and manufacturing services including FFS custom synthesis, API development, and compound analysis in addition to building blocks, intermediates, and impurity products for sale.

6000 Poston Road Athens, OH , 45701 United StatesStirling Ultracold is a developer and manufacturer of a new generation of energy-saving, environmentally-friendly ultra-low temperature freezers which operate over a range of -86°C to -20°C. The product line includes an upright 27.5 cu.ft. cabinet (780 liter), plus a 3.7 cu.ft. (105 liter) undercounter ultra-low freezer and a portable 0.9 cu.ft. (25 liter) ultra-low freezer.

8741 Apalachee Dr Cincinnati, OH. 45249, USAStrategic Regulatory Consulting offers consulting services in drugs, medical devices and biologics.

525 East Market Street Akron, Ohio, 44304 United StatesSumma Center for Pre-clinical Research and Skills Training (PRST) The Summa Center for Pre-clinical Research and Skills Training is staffed with a team of professionals that: Support the development and conduct of pre-clinical research studies using animals Support the development and conduct of educational programs that are focused upon experimental and applied surgery, using both animate and inanimate models Education Programs The skills lab hosts a range of skills programs including laparoscopic training, suture/knot tying training, endoscopy and microsurgery training. The PRST is a regional testing site for the Fundamentals in Laparoscopic Surgery. The PRST also provides full service support for industry sponsored education programs. These support services include OR video feed, access to classrooms, video/computer support, catering, animate labs, and wet lab space. Research Programs The PRST also supports the development and conduct of applied surgical research projects using animal models. The PRST staff is experienced with laboratory animal management, husbandry and surgical techniques. The staff welcomes the opportunity to discuss your research needs. Facilities & Equipment The PRST is an AAALAC accredited and USDA registered research facility and features two fully equipped aseptic surgery suites, a microsurgery suite, a training and education suite and all necessary ancillary support rooms. Specialized equipment that is available includes inhalation anesthesia, electro-surgery units, microsurgery scope, ultrasound, EKG and physiologic parameter monitors, 5 high definition laparoscopic surgery towers with HD video capture. The lab also features digital photography/video systems along with a computerized data/image collection and analysis system.

413 Northland Blvd Cincinnati, OH 45240-3210 USASiloam Biosciences has developed the novel Optimiser™ microfluidic microplate as a solution for rapid, ultra-sensitive, and cost effective immunoassays in the lifesciences research sector.

9435 Waterstone Boulevard Suite 100 Cincinnati, OH 45249Synchrogenix partners with pharmaceutical and biotech companies to develop submission documents for global regulatory agencies. Since 1986, our core competency at Synchrogenix has been regulatory writing for the pharmaceutical and biotech industry. Focusing on this crucial aspect of the drug development process has allowed us to hone our unique methodology and build a team of regulatory writers who are experts and thought leaders in the field. Rather than vertically specializing in a functional area, as a CRO, CMO, or contract lab might, Synchrogenix horizontally bridges all functional areas within drug development. Our strength is integrating with key stakeholders to create submission documents that are comprehensive, concise, and clear, as well as consistent within and across the entire submission. Synchrogenix breaks through silos, uniting many single elements into one story…your story. Synchrogenix is a leader in the regulatory writing field with a singular focus of authoring and editing regulatory documentation. We know that we are only as good as the documents that we produce. Therefore we are dedicated to the following ideals: Nurturing our writers and editors to increase their knowledge of drug and biological development, and to ensure they are comfortably challenged in their careers. Remaining immersed in global pharmaceutical, biotech, device, and diagnostics regulatory documentation requirements, to understand and anticipate our clients’ needs. Ensuring that we utilize technologies and safety systems that offer the level of sophistication that is vital to our clients. By merging our cross-functional expertise with our writing experience, we deliver documents that not only support clients’ strategic messaging, but also enhance their marketability. We provide many of the benefits of in-house writers—including the experience and perspective of industry insiders—without increased overhead or struggles with fluctuating workloads.

3333 Burnet Ave., MC7009 Cincinnati, OH 45229 USASeven Hills Bioreagents, a venture of Cincinnati Children's Research Foundation, supplies adenoviral vectors, antibodies, cell lines, and peptides.

5960 Heisley Road

5708 E. Schaaf Road Independence, Ohio 44131

759 Wessel Drive, Suite 6STATKING Consulting offers phase I-IV clinical research services including clinical data management, study monitoring, trial management, and feasibility studies.

3570 Pleasant Ave Hamilton, OH, 45015 United StatesSTATKING Consulting offers phase I-IV clinical research services including clinical data management, study monitoring, trial management, and feasibility studies.

4401 Dayton-Xenia Rd. Dayton, OH, 45432 United StatesSoBran BioScience supports drug discovery and medical research with high quality technical support for laboratory research projects and professional and responsible animal care programs.

4401 Dayton-Xenia Road Dayton, OH 45432 USASoBran BioScience supports drug discovery and medical research with high quality technical support for laboratory research projects and professional and responsible animal care programs.

Central ParkwayThe Institute of Human Genetics offers genomic, microscopy, and sequencing services.

10498 Montgomery Road, Montgomery, OH 45242, USA Partner in Innovation and Medical Education doctor and patient Innovation and Medical Education are the focus of the TriHealth Minimally Invasive Training Center (MITC). We partner with clinicians and sponsors in the pursuit of advancing surgical techniques and quality improvement- both in technique and device advancements. Our facility hosts two daVinci Robots that can be used for training courses. These courses take place within our newly renovated lab which helps to cultivate creative ideas, innovation and education. The TriHealth MITC is designed exclusively for healthcare practitioners and medical industry professionals to participate in and/or conduct educational, hands-on training courses to advance the quality of patient care through new medical research, techniques and/or device development assistance. Our goal is to help facilitate the learning of sound surgical techniques while helping sponsors and clinicians expound new ones. We continue to explore the use of innovative technologies and strategies. The TriHealth Hatton Research Institute is a well-known leader, counting among its resources leading-edge research, product development assistance, translational outcomes and quality improvement.

10498 Montgomery Road Suite A Cincinnati, OH, 45242 United StatesA Partner in Innovation and Medical Education doctor and patient Innovation and Medical Education are the focus of the TriHealth Minimally Invasive Training Center (MITC). We partner with clinicians and sponsors in the pursuit of advancing surgical techniques and quality improvement- both in technique and device advancements. Our facility hosts two daVinci Robots that can be used for training courses. These courses take place within our newly renovated lab which helps to cultivate creative ideas, innovation and education. The TriHealth MITC is designed exclusively for healthcare practitioners and medical industry professionals to participate in and/or conduct educational, hands-on training courses to advance the quality of patient care through new medical research, techniques and/or device development assistance. Our goal is to help facilitate the learning of sound surgical techniques while helping sponsors and clinicians expound new ones. We continue to explore the use of innovative technologies and strategies. The TriHealth Hatton Research Institute is a well-known leader, counting among its resources leading-edge research, product development assistance, translational outcomes and quality improvement.

20 S Third Street Columbus, OH 43215At Truven Health Analytics™, our purpose is to make healthcare better — lower costs, improved quality, better results. Simple words. Yet remarkably complex concepts. But that's not stopping us. Or our customers. Every day, we get to work with smart, passionate professionals, from every facet of the industry, as they manage change and implement strategies that will achieve exactly those outcomes. Our customers are healthcare payers and providers. In both the private and public sectors. They're researchers and suppliers. Regulators. Movers and shakers in each piece and part of the healthcare world. With this broad view of healthcare, we're able to see when new challenges are just beginning to emerge. And that's when we begin working on new solutions. Data. We're driven by it. Known for our exacting collection and secure management of data, we've worked with clinical evidence, claims, clinical, and other healthcare data for more than 40 years. We know the challenges to watch for, what to do about them — and how to recognize new ones. Like finding new ways to measure risk for providers who take on more of it, and payers who contract for it. Or integrating data to deliver the solutions today's converging healthcare interests demand. Analytics. Because data alone is just numbers and letters. The need for reliable insights from data demands proven analytics. Our methodologies and algorithms are uniformly trusted across the industry to deliver critical information that leads to confident decisions. Coupled with flexible reporting, integration, and consulting services, our sophisticated analytics enable our customers to make their part of healthcare better, faster. Domain expertise. We have it. We really have walked in our customers' shoes. We've worked in their environments. That level of understanding, plus our leading data management capabilities and advanced analytics, are why our customers turn to us as their partner to deliver quality, reduce costs, and yield greater value in healthcare.

1901 Research Blvd.The McConnell Group provides sci med products, life science services, training, and staffing.

2870 Salt Springs Road Youngstown, OH, 44509 United StatesWelcome to Tri-State Labs Inc. (TSL) along with its division Environmental Control Labs (EC Labs). The leaders in environmental services. Our services are not limited to the tri-state area but we also accept analytical work from anywhere in the United States and are actively pursuing international business. TSL also handles forensic science work and is judicially recognized for expert testimony.

Strongsville Research Center 16651 Sprague Rd. Strongsville OH 44136 USATechDirect Analytical Services provides material characterization, rheology, spectroscopy, thermal analysis, and particle size analysis.

Strongsville, OH United StatesTechDirect Analytical Services provides material characterization, rheology, spectroscopy, thermal analysis, and particle size analysis.

3600 Gantz Road, Grove City, OH 43123-1895Tosoh offers ceramic materials, fine chemicals, fluoro compounds, organic intermediates, and polymer products and services.

4520 Willow Parkway Cleveland, Oh 44125

122 Broad Blvd Cuyahoga Falls, OH, 44221 United StatesChemistry consultant

77 Milford Drive Hudson, OH, 44236 United StatesTaazaa is a Ohio Corporation with expertise in Custom Application Development (desktop & web), Mobile Apps (native and cross-platform), Product Engineering, and Managed & Cloud Hosting Taazaa holds a competitive advantage in offering a broad range of services based on successful execution of product development in logistics, healthcare, retail and more. Taazaa is valued by our partners for delivering quality development, in a timely lifecycle, at a very competitive price point.

77 Milford Dr. #251 United States Hudson, OH, 44236 United StatesTaazaa is a Ohio Corporation with expertise in Custom Application Development (desktop & web), Mobile Apps (native and cross-platform), Product Engineering, and Managed & Cloud Hosting Taazaa holds a competitive advantage in offering a broad range of services based on successful execution of product development in logistics, healthcare, retail and more. Taazaa is valued by our partners for delivering quality development, in a timely lifecycle, at a very competitive price point.

3125 Eden Avenue Cincinnati, OH, 45219 United StatesUniversity of Cincinnati Center for Biological Microscopy (CBM) provides equipment, consultation, training, or labor for transmission electron microscopy, confocal microscopy, widefield light microscopy, live cell microscopy, image analysis, and digital macroscopic imaging.

Cardiovascular Research Center Room 4944 231 Albert Sabin Way Cincinnti, OH, 45267 United StatesThe mission of the Inhalation Core Facility is to provide a controlled exposure system to mimic both first hand cigarette smoke exposure and second hand smoke exposure using a whole body exposure system. In addition, we can provide individual mouse organs, serum, and cigarette smoke extract.

Medical Sciences Building Room 253 231 Albert Sabin Way – ML 0769 Cincinnati, OH, 45267-0769 United StatesThe Participant Recruitment and Clinical Research Service Center is a unique resource provided by the University Of Cincinnati Department Of Emergency Medicine to support research conducted across the Academic Health Center. The Center is staffed by a team of clinical research coordinators (CRC) and clinical study assistants (CSA). Together, they provide a centralized, coordinated approach to screening and recruiting patients for research participation, collecting and processing specimen samples and data, and entering data into clinical trial databases.

300 College Park Dayton, OH, 45469 United StatesAt the University of Dayton, we learn by doing, because doing transforms education. Whether it's breaking ground on campus to do groundbreaking work with GE Aviation, staying ahead of the economic curve by opening an institute in China or increasing our global foothold by reducing our local footprint, we're rolling up our sleeves and taking action to create a better tomorrow.

Department of Otolaryngology, Head and Neck SurgeryTübingen Hearing Research Center (THRC) of the University of Tübingen focuses on research in otology.

Toledo, OH United StatesUniversity of Toledo focuses on research and offers its flow cytometry, microarray, microscopy, and clinical facilities to support the research community.

Akron, OH

11100 Euclid Ave Cleveland, OH, 44106 United StatesThe history of University Hospitals Cleveland Medical Center is linked to the history of Cleveland. Founded in 1866, we were nurtured and supported by Cleveland’s great industrial families of the late 19th and early 20th centuries – the same families that played key roles in the development of the city’s noted civic and cultural institutions, including the Cleveland Museum of Art, The Cleveland Orchestra, and The Cleveland Foundation. Among the forward-looking thinkers in our early history was industrialist Samuel Mather, who served as a trustee for an astounding 47 years, including 32 years as chairman. In 1891, Mather visited the fledgling Johns Hopkins hospital and medical school. He returned to Cleveland convinced of the value of an academic medical mission joined with patient care. He understood the synergy created in an academic medical center that brings together the power of healing, teaching and discovery, and he recognized that the future of great medicine lay in the academic medical center model. This vision for University Hospitals led in 1895 to our formal ties with what is now the Case Western Reserve University School of Medicine. As an affiliate of the medical school, we grew to become one of the nation’s great centers of academic medicine and the region’s leading provider of high quality health care. To the people of Greater Cleveland, we came to exemplify hope, mercy and humanity.

240 Albert Sabin Way, Location S, Suite 2.500 Cincinnati, OH, 45229 United StatesThe Center for Clinical and Translational Science and Training (CCTST) was established by the UC College of Medicine in October 2005. The CCTST is directed by James Heubi, MD, Professor of Pediatrics and Associate Dean for Clinical and Translational Research, with support from the program directors and staff. Centrally located on the 2nd floor of the CCHMC ‘S’ Building, the CCTST serves UC, its Academic Health Center partners and the Community by: Providing consultation to investigators on research design and implementation through Research Central Providing support for young investigators (faculty and fellows) in clinical and translational research through help in preparing career development awards (e.g., K23; timeline) Assisting young faculty in careers in clinical and translational research Assisting faculty in preparing large multidisciplinary, multi-school, and multi-institutional grants Helping individual divisions and departments to prepare proposals for T32 and similar training grants Spearheading efforts to write institutional training grants Coordinating clinical and translational research Coordinating the MS in Clinical and Translational Research Training Program. A Certificate in Clinical and Translational Research is also offered.

2033 Mowry RoadUniversity of Florida ICBR provide proteomic, genomic, bioinformatics, cellomic services.

CampusUniversidade Federal de Santa Catarina (UFSC) focuses on research.

2120 E. Galbraith Rd. Cincinnati, OH, 45237 United StatesMission: Our mission is to advance medical and biological research by providing the scientific community with standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders. We specialize in the immunological aspects of Type I diabetes, measurement of various glucose and lipid metabolism parameters relevant to Type II diabetes as well as diabetic complications such as heart disease and obesity. The University of Cincinnati Mouse Metabolic Phenotyping Center is a comprehensive resource for the phenotypic characterization of mouse models pertaining to the study of diabetes and its complications. The Center is one of multiple Mouse Metabolic Phenotyping Centers supported by the National Institutes of Health (NIDDK). Our mission is to advance medical and biological research by providing the scientific community with standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders. We specialize in the immunological aspects of Type I diabetes, measurement of various glucose and lipid metabolism parameters relevant to Type II diabetes as well as diabetic complications such as heart disease and obesity.

Medical Science Building Room 1153D 231 Albert Sabin Way Cincinnati, OH, 45267-0529 United StatesThe University of Cincinnati Cancer Institute’s Tumor Bank is a strictly organized and structured operation that provides researchers access to thousands of human specimens—malignant and paired normal tissues, blood, saliva and urine—as well as associated clinical data. Patients who choose to donate their tissue or other biospecimens offer researchers at the UC Cancer Institute a tremendous gift. Our goal is to preserve those samples with best-practice standards and deliver it to researchers with the most promising ideas. The Tumor Bank operates under rigid standards for collecting, processing, storing and distributing biospecimens to ensure that there is no separation between procedures on paper and realities at the research bench. The Tumor Bank Scientific Research Committee reviews requests for samples. Access is granted based on scientific merit and quality to ensure samples are utilized effectively, with respect to the patients who donated them.

9261 Ravenna Rd., Ste B7 Twinsburg, OH 44087US Materials Group provides products for blood and urine collection.

11297 Grooms Rd Blue Ash, OH, 45242-1428 United StatesUpstream360 is the Product Communication Agency. We specialize in product innovation, product concept development, and product story development. We turn science and technologies into compelling product communication assets for use with consumers, patients, scientists, and medical professionals. A curiously-nerdy mixture of scientists, strategists, innovators, and creatives, we partner with the worlds leading CPG and Pharma companies to simplify the complex and explain the product science in a surprisingly obvious way. From static illustration and copywriting to mechanism/mode of action video and animation production, we can help with all your Product Communication needs.

735 Hollibaugh Avenue,VDM Biochemicals provides drug design, virtual screening, custom synthesis, chemicals, and specialty products.

5933 summit St Sylvania, Ohio, 43560 United StatesWe are a human organ and tissue supply company. Based in the US. We work with ethical and FDA approved organ and tissue procurement agencies to supply quality organs and tissues to researchers. These are typically organs and tissues that are not used for transplant at the time of procurement, but are transplant quality and make great research and or education specimens. Large and continuous volumes available. Recovery, packaging and transport can be tailored to meet your needs. Organs, Tissues, Placenta, Umbilical cord, body fluids, vessels, Bone marrow, etc. The possibilities are limitless. We work with you to meet your needs.

2215 International Parkway North Canton, OH 44720 United StatesWacker offers contract manufacturing, biologic analysis, and quality control/assurance services.

10860 Kenwood Road Cincinnati, Ohio 45242Wolf Group provides consumer panels, sensory evaluation, quality control, product matching, fundraising services, and concept testing.

6954 Cornell Road Suite 200 Cincinnati OH 45252 USAAdvanced Testing Laboratory offers analytical chemistry, microbiology, enurinomental testing, consulting, and engineering testing.

Broadway Street Toledo, OH United StatesAdvanced Clinical Diagnostics Labs provides microorganisms, tissue culture/cell lines, cell-based assay systems, antibody services, toxicology, and device testing.

1021 BROADWAY Toledo OH 43609-2505Advanced Clinical Diagnostics Labs provides microorganisms, tissue culture/cell lines, cell-based assay systems, antibody services, toxicology, and device testing.

Wright-Patterson AFB, OH, AFRLThe Air Force Research Laboratory (AFRL) is the Air Force's only organization wholly dedicated to leading the discovery, development, and integration of warfighting technologies for our air, space and cyberspace forces. We trace our roots to the vision of airpower pioneers who understood science as the key to air supremacy. The passionate commitment of AFRL people, to realize this vision, has helped create the world's best air, space and cyberspace force.

Mentor, OH, 44060 United StatesAmerican Polymer Standards Corporation (APSC) is an independent contract laboratory specializing in molecular weight distribution analysis by various determination methods. Methods used are Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC); Multi-Angle Laser Light Scattering (MALLS) and Vapor Pressure Osmometry (VPO).

8680 Tyler Blvd. Mentor, OH 44060 USAAmerican Polymer Standards Corporation (APSC) is an independent contract laboratory specializing in molecular weight distribution analysis by various determination methods. Methods used are Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC); Multi-Angle Laser Light Scattering (MALLS) and Vapor Pressure Osmometry (VPO).

Columbus, OH United StatesApplied Laboratories Inc specializes in manufacturing and packaging.

845 Center Drive Vandalia OH 45377 USAAptalis provides controlled drug release, dosage form, bioavailability enhancement, and drug targeting.

422 W. Guthrie Street, Upper Sandusky, OH 43351Wannemacher Packaging Spray Drying’s One Source – One Solution concept offers all this – and more – to you: More than 30 years of contract manufacturing experience in the spray drying process with an emphasis on food products. Kosher, FDA and Department of Agriculture certifications. Coulter modified three-stage drying tower produces 750 pounds per hour. Consistently high yield averages at 98% (above industry standard) 24 hour production schedule, seven days per week. We can process your pre-mixed liquid or we can custom-blend your liquid for you. Continuous in-house testing to insure your product’s consistency. The finest inventory control, warehousing and distribution systems available to track, store and ship your product. Our Upper Sandusky plant location in Western Ohio is within 600 miles of 60% of the nations population.

Albany, OH, 45710 United StatesWetzel Chemistry Consulting provides consulting for compound design, IP protection, CMC management, and infrastructure design.

1425 Glenoak Dr. Tallmadge, OH 44278

Cincinnati, OH United StatesAusio Pharmaceuticals offers clinical studies and preclinical testing.

Cincinnati, OH, USAAusio Pharmaceuticals offers clinical studies and preclinical testing.

214 W. Bowery St. Akron , OH 44308

6560 Gove Court Mason OH 45040 USAAniara offers diagnostic and research reagents, as well as screening tools.

501 West 1st Avenue Columbus, OH 43215 USAABITEC Corporation combines synthesis and analytical expertise in organic compounds with a high quality manufacturing operation to offer a wide range of exceptional ingredients its customers.