calle San Benito 48 Madrid, Madrid, 28029 Spain3DforScience is a Global Scientific Communications helping pharmaceutical, biotechnology, medical device and healthcare companies to visualize and explain their science. Our mission is to provide illustrative content and visual aids for the medical, health and technology related industries through 3D animations, Virtual Reality and interactive production to enhance the clients’ health and marketing communications. Focused on helping and advising companies in the health and biotechnology sector, allowing them to explain technologies, research or new therapies and transmit them in an innovative and visual way to differentiate themselves from the competition or make more comprehensible our advances to institutions, clients, partners and society.

Paseo de la Castellana 141 Edificio Cuzco IV Planta 20 28046 Madrid SpainAccovion provides regulatory consulting, medical services, clinical management, and pharmacovigilance.

C/Santiago Grisolia 2, D132 Tres Cantos, Madrid PCM 28760 SpainAgrenvec supplies and produces recombinant proteins and monoclonal/polyclonal antibodies.

Madrid, Community of Madrid SpainAgrenvec supplies and produces recombinant proteins and monoclonal/polyclonal antibodies.

Parque Tecnologico Tecnobahia Puerto de Santa Maria, SpainAgroaxis sprouted as an innovating idea from the founder member, who owns a deep market insight thanks to more than 35 years experience in the biopharmaceutical field. The company was established in 2010 and just three years, the company is nominated as the ten top in the word as biosimilar`s with the support of the European Union, Public Administration, through founding aimed at the development of R&D SMEsCurrently, it also boasts its own Research Center, 3200 m2, located in the Parque Tecnologico Tecnobahia Puerto de Santa Maria (Spain). Additionally, it is working in laboratory situated in El Puerto de Santa María (Spain). Agroaxis is currently the only one company in Spain that is integrated from bench to production and commercialization of biosimilars, among other therapeutic proteins, through a plant based protein expression system. The vision of Agroaxis is to become the reference in the pharmaceutical sector regarding the production and commercialization of nutraceutics and CMO services. It aims at being a leading company in its area, both on the national and international scale, thanks to its commitment with the high quality standards of its products and services. The mission of the company is the research, development, production and distribution of pharmaceutic and biopharmaceutic products and services. It has specialized in the production of therapeutic proteins. To this aim, Agroaxis has developed highly competitive processes of molecular biology that are based on expression systems, industrial scale plant culture, extraction and purification of proteins., all this using plant biofactories. The values that integrate the Agroaxis culture are focused on directing the whole company to address the client´s requirements: leadership, integrity, flexibility and efficiency. Agroaxis´ staff is integrated by 8 people. 90% of them are exclusively devoted to R&D&I and everyone were hired through the INNCORPORA TU and INNCORPORA FPGS, programs, which are aimed at the recruitment of qualified staff.

Avenida de Manoteras 22 nave 116 Madrid, Comunidad de Madrid, 28050 SpainAilin is an end-to-end Diagnostics-as-a-Service platform that enables large-scale, out-of-clinic screening programs for disease awareness, early risk identification and real-world evidence (RWE) generation. The platform connects remote sample collection (e.g., capillary blood, urine, saliva), certified laboratories, AI-assisted medical reporting, HCP dashboards, patient engagement tools and anonymized data registries. Ailin is designed to support pharmaceutical companies, laboratories and healthcare stakeholders in deploying scalable screening initiatives, strengthening patient identification pathways and generating high-quality real-world data across countries.

45 Avenida de Alfonso XIII Madrid, Comunidad de Madrid, 28016 SpainAilin is an end-to-end Diagnostics-as-a-Service platform that enables large-scale, out-of-clinic screening programs for disease awareness, early risk identification and real-world evidence (RWE) generation. The platform connects remote sample collection (e.g., capillary blood, urine, saliva), certified laboratories, AI-assisted medical reporting, HCP dashboards, patient engagement tools and anonymized data registries. Ailin is designed to support pharmaceutical companies, laboratories and healthcare stakeholders in deploying scalable screening initiatives, strengthening patient identification pathways and generating high-quality real-world data across countries.

1 Calle del Marquesado de Santa Marta Madrid, Comunidad de Madrid, 28027 SpainAilin is an end-to-end Diagnostics-as-a-Service platform that enables large-scale, out-of-clinic screening programs for disease awareness, early risk identification and real-world evidence (RWE) generation. The platform connects remote sample collection (e.g., capillary blood, urine, saliva), certified laboratories, AI-assisted medical reporting, HCP dashboards, patient engagement tools and anonymized data registries. Ailin is designed to support pharmaceutical companies, laboratories and healthcare stakeholders in deploying scalable screening initiatives, strengthening patient identification pathways and generating high-quality real-world data across countries.

Calle del Marquesado de Santa Marta Madrid, Comunidad de Madrid, 28022 SpainAilin is an end-to-end Diagnostics-as-a-Service platform that enables large-scale, out-of-clinic screening programs for disease awareness, early risk identification and real-world evidence (RWE) generation. The platform connects remote sample collection (e.g., capillary blood, urine, saliva), certified laboratories, AI-assisted medical reporting, HCP dashboards, patient engagement tools and anonymized data registries. Ailin is designed to support pharmaceutical companies, laboratories and healthcare stakeholders in deploying scalable screening initiatives, strengthening patient identification pathways and generating high-quality real-world data across countries.

Carretera M-300 km 29,920 Apartado de Correos 37 28802 Alcalá de Henares (Madrid)Alcalà Farma provides the service of comprehensive development and manufacturing of a new product

Calle Santiago Grisolia 2 Edificio Qube Tres Cantos, Madrid, 28760 SpainOn Science works for companies and research centers that need a scientific or technical support service in cell culture. Our laboratory offers a 360º cell culture service, from routine culture work to development of the research or test idea.

C/ Henares, 16-18 Velilla de San Anton Madrid, 28891 SpainBeslan is a full service contract manufacturer of herbal, vitamin, mineral, and dietary supplements. Beslan SL offers a comprehensive package of nutritional and nutraceutical products and services.

Vía de las dos Castillas, 33 Atica 7-Edificio 7 PLANTA 3 28224 Pozuelo de Alarcón (Madrid) SpainCasen Fleet provides pharmaceutical products, improvement of current products, market studies and analysis of projects.

Don Pedro 7 - 3D Madrid, Madrid, 28005 SpainThe Spanish Pharmacoepidemiological Research Center (CEIFE) was created in 1994 as a research center in Madrid. Its aim is the realization of high - quality epidemiological studies on safety and effectiveness of drugs, using automated databases. The main sources of information are four medical databases: Clinical Practice Research Datalink and The Health Improvement Network, both in Britain BIFAP database and database Saskatchewan in Canada.

Calle Almte., 28 Calle Almte., 28, 28004 Madrid, EspañaThe Spanish Pharmacoepidemiological Research Center (CEIFE) was created in 1994 as a research center in Madrid. Its aim is the realization of high - quality epidemiological studies on safety and effectiveness of drugs, using automated databases. The main sources of information are four medical databases: Clinical Practice Research Datalink and The Health Improvement Network, both in Britain BIFAP database and database Saskatchewan in Canada.

Madrid, SpainCentro Nacional de Invest. Cardio. provides cytometry, proteomics, transgenesis, viral vectors, microscopy, and gene targeting.

C / Melchor Fernández Almagro, 3 Madrid, E-28029 SpainCentro Nacional de Investigaciones Oncologicas (CNIO) focuses on research in cancer and offers its facilities to provide cytogenetics, molecular diagnostics, histopathology, DNA sequencing, tumor banking, and DNA microarray services.

C/ Melchor Fernández Almagro 3 Madrid, Madrid, 28029 SpainThe National Cancer Research Centre (CNIO) was created in 1998 by the Institute of Health Carlos III, although it was founded by the Ministry of Health, the CNIO is integrated since the end of 2011 in the Ministry of Economy and Competitiveness . The CNIO is managed by a foundation, created simultaneously with the Center, whose name is that of the Carlos III National Center for Cancer Research Foundation. The Foundation has the status of state - owned foundation and is governed by a Board . Center corresponds develop scientific activity and is headed by a Director and assisted by a Scientific Advisory Committee The essential mission of the CNIO is to carry out research of excellence and to offer innovative technology in the field of cancer to the National Health System and to the National System of Science and Innovation. For this purpose, the strategic objectives of the CNIO are: To carry out an investigation to obtain new and more effective methods of diagnosis and treatment of oncological diseases. To transfer the scientific knowledge to the clinical practice, obtaining that the scientific advances repercuss as soon as possible on our sanitary system and, therefore, on the well-being of the patients. Transfer the technology developed in the CNIO to innovative companies. Establish a new and more effective management system in the European scientific field. The CNIO is one of the few European cancer centers that destines its resources to basic and applied research under an integrated approach, favoring the interaction of basic research programs with those of molecular diagnosis and discovery of new drugs, all supported by a Solid equipment infrastructure and technical services. The management system of the CNIO combines business flexibility, which derives from its founding nature, with the accounting rigor derived from its status as a state-owned foundation and from the control and justification of the public funds received.

C/ Hermanos del Moral 13 (Bajo E Madrid, 28019 SpainCliniSciences is a European distributor of products & services from suppliers based all around the world. With a direct presence in 18 countries, CliniSciences serves customers through its own commercial and technical teams in Austria, Belgium, Denmark, Finland, France, Germany, Iceland, Ireland, Italy, the Netherlands, Norway, Poland, Portugal, Spain, Sweden, Switzerland, the United Kingdom, and the United States. Through these companies, CliniSciences offers a broad portfolio of life science reagents, instruments and services for research and diagnostic applications. Our product range includes reagents, antibodies, cells, assay kits, instruments, and a strong offering of human biological samples, including blood-derived products, tissues, primary cells, biofluids, DNA/RNA and other clinically relevant biospecimens. Our services include antibody development, peptide and protein synthesis, bulk manufacturing, humanization, custom production and other tailored solutions to support life science, biotech and diagnostic projects.

2 Calle Quintanavides Edificio Gorbea lll Madrid, Comunidad de Madrid, 28050 SpainCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

Plaza de Ramón y Cajal Madrid, Comunidad de Madrid, 28040 Spain

C/Santaigo Grisolía, 2 28760 Tres Cantos, Madrid SpainEnzymlogic is a world leader in the kinetic profiling of compounds to facilitate drug discovery. As experts in the generation and interpretation of kinetic data, we pride ourselves on a proven track record of successful partnerships with worldwide organizations of all sizes, supporting them on a routine basis during the early phases of drug discovery. We focus on the Hit to Lead (H2L) and Lead Optimization (LO) stages of drug discovery where our optimized kinetic profiling assays identify compounds with therapeutic potential that merit further progression into clinical trials. Our expertise in protein science and high-throughput screening enables drug hunters to speed up discovery decision-making, choosing the most promising molecules and eliminating under-performers, through a deeper understanding of the kinetics of compound-target interactions. We use exquisitely tuned assays to deliver accurate, robust and reproducible kinetic data of the highest quality that enhances the identification of compounds with the greatest therapeutic potential. The insight we provide facilitates the screening of compounds to iterate medicinal chemistry, understand pharmacokinetics/pharmacodynamics (PK/PD) disconnects and build better models to define therapeutic windows.

C/ General Ibáñez de Íbero, 1 28003 Madrid SpainEurodiagnóstico specializes in the distribution of ELISA reagents and kits for animal and human research and also in developing and manufacturing research products for molecular and cell biologists.

Paseo de la Castellana 177, 7ºD 1 28046 Madrid, SpainEurotrials, Scientific Consultants, is a privately owned company founded in Lisbon in 1995 by members of academia, medical community and pharmaceutical industry. It specializes in clinical research and scientific consultancy in the area of health and currently operates in Europe and Latin America. Eurotrials’ close collaboration with medical and regulatory institutions is an essential success factor that has been recognized by its partners, i.e. the pharmaceutical and international biotechnology industry, regulatory agencies, universities and clinical research centres., CROs and agro-food industry. The company’s success stands on pillars that have marked its personality since it was founded: creativity in finding solutions, unique technology, multidisciplinary expertise, solid experience and quality. It is qualified to participate in all the steps of any clinical, translational or epidemiological research project, from the initial research question to the final output. Eurotrials has a team of over 120 young, motivated employees and counts on diversity and interdisciplinarity to meet its customers’ needs. The team includes physicians, biologists, pharmacists, biostatisticians, sociologists, nutritionists, chemists, engineers, psychologists and mathematicians, among others.

Parque Científico de Madrid C/ Faraday 7 Madrid, Madrid, 28049 SpainEvoEnzyme designs engineered enzymes for the pharmaceutical, chemical and environmental industries through directed evolution. The company specializes in customized biocatalysis projects.

C/GRECIA 80-4 MADRID, MADRID, 28341 SpainEvoEnzyme designs engineered enzymes for the pharmaceutical, chemical and environmental industries through directed evolution. The company specializes in customized biocatalysis projects.

Madrid, Community of Madrid SpainFarmasierra offers services to mangage, distribute, promote, develop and optimize the production of medicinal products.

Carretera de Irún Km. 26,2000. 28700 San Sebastián de los Reyes Madrid SpainFarmasierra offers services to mangage, distribute, promote, develop and optimize the production of medicinal products.

Avda Reyes Católicos, 2 Madrid, 28040 SpainFundacion Jimenez Diaz focuses on research in therapeutic areas of cancer, cardiovascular disease, infectious disease, inflammatory disease, and metabolic diseases.

Madrid, Community of Madrid SpainFundacion Jimenez Diaz focuses on research in therapeutic areas of cancer, cardiovascular disease, infectious disease, inflammatory disease, and metabolic diseases.

Ctra. Colmenar Viejo km 9,100 Madrid, Madrid, 28034 Spain

Urb. Monteprincipe/Facultad de Farmacia/USPCEU Boadilla del Monte, N/A, 28668 SpainCompany: Fundación Universitaria San Pablo CEU. Research centre: CEMBIO, Centre for Metabolomics and Bioanalysis. Faculty of Pharmacy. Madrid, Spain

6 Calle de San Emilio Madrid, Comunidad de Madrid, 28017 SpainWe, León Research, are a Spanish CRO, providing outsourcing services all over Europe for the Pharma Industry, Biotech companies, Medical Devices Manufacturers, Food Industry and other CROs, with a wide experience on clinical research, developing Phase I to IV clinical trials, medical devices, observational and food studies. As a full service Contract Research Organization, our solutions include all the activities from design, setting up and monitoring of clinical trials and research studies, up to the management of data, statistical analysis and medical writing, covering the whole process to introduce new medical devices and pharmacy products on the market. In Leon research, we promote intelligence and creativity as the two key factors on scientist research and we also believe that quality, in the framework of the GCP/ICH, as well as flexibility to adapt our services, are what warranties the success. We know better how to manage global studies, because by conducting local clinical trials, we can offer a better local knowledge which accelerates and facilitates the final result.

CALLE RONDA DE PONIENTE 6 TRES CANTOS, MADRID, 28760 SpainWorld leader in the field of telomere diagnostics, operating in more than 35 countries. High throughput (384-well format) and automated laboratory for measuring telomere length profiles in single cell resolution, telomerase activity, and ALT assays for aging, cancer, and regenerative medicine fields, with a spinning disk confocal microscopy (Revvity Opera Phenix HC). We offer a wide range of research services based on in vitro testing for a specific treatment and in vivo models, among others: - TAT: Our proprietary technology (HT-Q-FISH) for the analysis of the whole telomere length distribution (> 223 variables). With this technology, we are also capable of assessing ALT (Alternative Lengthening of Telomeres). - Q-TRAP assay: Quantitative determination of telomerase activity by qPCR. - hTERT expression: Quantification of the mRNA of the catalytic subunit of human telomerase. - RNAscope™: Detection of any mRNA within cells and tissues. Label and measure telomere length (TAT) in specific cellular populations. - Q-FISH (single cell resolution): Cellular senescence (b-gal), oxidative stress (ROS), mitochondrial assessments, DNA damage (H2AX) with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

Calle de Miguel Angel 11 Madrid, Madrid, 28010 SpainWorld leader in the field of telomere diagnostics, operating in more than 35 countries. High throughput (384-well format) and automated laboratory for measuring telomere length profiles in single cell resolution, telomerase activity, and ALT assays for aging, cancer, and regenerative medicine fields, with a spinning disk confocal microscopy (Revvity Opera Phenix HC). We offer a wide range of research services based on in vitro testing for a specific treatment and in vivo models, among others: - TAT: Our proprietary technology (HT-Q-FISH) for the analysis of the whole telomere length distribution (> 223 variables). With this technology, we are also capable of assessing ALT (Alternative Lengthening of Telomeres). - Q-TRAP assay: Quantitative determination of telomerase activity by qPCR. - hTERT expression: Quantification of the mRNA of the catalytic subunit of human telomerase. - RNAscope™: Detection of any mRNA within cells and tissues. Label and measure telomere length (TAT) in specific cellular populations. - Q-FISH (single cell resolution): Cellular senescence (b-gal), oxidative stress (ROS), mitochondrial assessments, DNA damage (H2AX) with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

Calle Faraday 7, Campus de Cantoblanco Parque Científico de Madrid Madrid, Madrid, 28049 SpainWorld leader in the field of telomere diagnostics, operating in more than 35 countries. High throughput (384-well format) and automated laboratory for measuring telomere length profiles in single cell resolution, telomerase activity, and ALT assays for aging, cancer, and regenerative medicine fields, with a spinning disk confocal microscopy (Revvity Opera Phenix HC). We offer a wide range of research services based on in vitro testing for a specific treatment and in vivo models, among others: - TAT: Our proprietary technology (HT-Q-FISH) for the analysis of the whole telomere length distribution (> 223 variables). With this technology, we are also capable of assessing ALT (Alternative Lengthening of Telomeres). - Q-TRAP assay: Quantitative determination of telomerase activity by qPCR. - hTERT expression: Quantification of the mRNA of the catalytic subunit of human telomerase. - RNAscope™: Detection of any mRNA within cells and tissues. Label and measure telomere length (TAT) in specific cellular populations. - Q-FISH (single cell resolution): Cellular senescence (b-gal), oxidative stress (ROS), mitochondrial assessments, DNA damage (H2AX) with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

calle General Martinez Campos, 46 Madrid, Madrid, 28010 SpainWorld leader in the field of telomere diagnostics, operating in more than 35 countries. High throughput (384-well format) and automated laboratory for measuring telomere length profiles in single cell resolution, telomerase activity, and ALT assays for aging, cancer, and regenerative medicine fields, with a spinning disk confocal microscopy (Revvity Opera Phenix HC). We offer a wide range of research services based on in vitro testing for a specific treatment and in vivo models, among others: - TAT: Our proprietary technology (HT-Q-FISH) for the analysis of the whole telomere length distribution (> 223 variables). With this technology, we are also capable of assessing ALT (Alternative Lengthening of Telomeres). - Q-TRAP assay: Quantitative determination of telomerase activity by qPCR. - hTERT expression: Quantification of the mRNA of the catalytic subunit of human telomerase. - RNAscope™: Detection of any mRNA within cells and tissues. Label and measure telomere length (TAT) in specific cellular populations. - Q-FISH (single cell resolution): Cellular senescence (b-gal), oxidative stress (ROS), mitochondrial assessments, DNA damage (H2AX) with confocal microscopy. - AlphaLISA®: Quantify from large macromolecular complexes to small molecules with high sensitivity and robustness. - EliSpot: measure cell secretions (cytokines, antibodies, granzyme…) at a single cell level. Ideal for compound screening.

C/ Las Norias 92, Planta 2ª Edificio Nuestra Señora del Pilar Madrid, 28221 SpainLinical is a public, mid-sized Contract Research Organization headquartered in Japan with a significant presence across all major markets including North America, Europe, and Asia-Pacific. Linical provides the full spectrum of drug development services from early stage to large-scale, multinational studies. Our areas of focus include Phase I-IV studies in oncology, neurology & psychiatry, immunology & vaccine, and endocrinology & metabolic diseases.

Solana nº 26 28850 Torrejón de Ardoz Madrid - SpainMedinsa develops, produces, manufactures, packages and distributes solid oral dosage form pharmaceuticals.

Address: #250 D,Metropolis Healthcare offers clinical research services as well as pathology testing, DNA extraction, and specimen archival.

Madrid, Community of Madrid SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Parque científico de Madrid - C/Faraday, 7 (Campus de Cantoblanco) Madrid, 28049 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Calle Anabel Segura 16 Edificio Vega Norte - Ed. 3 1ª planta Alcobendas, Madrid, 28108 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

c/ Faraday 7 Madrid, Madrid, 28049 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Avenida Isla Graciosa 3 San Sebastian del los Reyes, Madrid, 28703 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Calle Faraday 7 Parque Científico de Madrid Madrid, Madrid, 28049 SpainNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Calle del Doctor Fleming, 51 - 1 Madrid, Madrid, 28036 SpainOXON Epidemiology is a European-based, full-service Contract Research Organization (CRO) combining advanced scientific expertise with global operational capability to deliver Real-World Evidence (RWE) and RWE-driven clinical research solutions. We support pharmaceutical and medical device companies with strategic, scientific, and executional services across the full product lifecycle—from early-phase development through post-marketing. Our offerings include observational studies (field, database, and hybrid), pragmatic trials, disease/product registries, evidence synthesis (systematic reviews, meta-analyses), and full-phase clinical trials (I–IV). We address needs in safety, clinical effectiveness, HEOR, market access, and regulatory compliance. What sets OXON apart is our highly experienced, multidisciplinary team—epidemiologists, statisticians, health economists, clinicians, and qualitative researchers—combined with strong academic partnerships (e.g., London School of Hygiene & Tropical Medicine) and global collaborators. With MSAs in place with top-20 pharmaceutical companies and a publication record including 11 articles in The Lancet, we are trusted to deliver high-quality, cost-effective RWE worldwide. Our scale and structure allow for flexibility, senior team involvement, and client-focused delivery. We operate across Europe, LATAM, Asia, and North America, and are committed to scientific excellence, transparency, and impact on patient and public health.

C/ Faraday, 7 28049 Madrid, SpainSince our inception over twenty years ago, we have focused on developing a technical, administrative, and human resources infrastructure with a single purpose: to provide integrated quality, productivity and compliance services to highly-regulated manufacturers throughout the globe. To meet the needs of the times, we have integrated our services to make certain that all the compliance, risk-management, knowledge-management, and workforce needs of our global partners are addressed in ways that provide the desired operational and compliance result.

Ronda de Poniente 16, 1º A-F. Tres Cantos. 28760 Spain.ProAlt offers innovative proteins and antibodies and research services (CRO): protein expression, antibodies generation and recombinant antibodies production.

C / Ronda de Poniente, 16 - 1º AF Business Park EURONOVA Tres Cantos, Madrid, 28760 SpainProAlt offers innovative proteins and antibodies and research services (CRO): protein expression, antibodies generation and recombinant antibodies production.

Calle de Alfonso XII, 62 3rd floor, Office 3055 Madrid, Madrid, 28014 SpainTransforming imaging data into actionable predictions We design pioneering tools that unlock imaging data to improve patient outcomes. From clinical research to personalized care. Healthcare providers, biopharma companies, research and academic institutions and RWE specialists partner with Quibim to power up the imaging portion of their business, accelerating the arrival of precision medicine. Our unique multi-scale ways of seeing problems can guide decision-making at every stage in the drug development program. Quibim can reveal a full suite of novel imaging biomarkers from existing and new patient datasets to enhance the power of multi-omics: deeply analyze disease mechanisms, find the right candidates for clinical studies, stratify patients with different risks, predict patient outcomes and drug response and monitor treatment progress using a tissue-agnostic approach. As a global leader in medical imaging analysis and processing, our best-in-class software medical devices and solutions extract objective and highly accurate information versus traditional methods, using the latest AI technology. We have advanced image harmonization techniques generating a standardized image quality that minimizes variability across equipment manufacturers and acquisition protocols. Quibim has access to large scale databases and can analyze any image modality and any tissue from thousands of consecutive patients. *Please note that we do not analyze pathological images.

Madrid, Community of Madrid SpainQuosPharma specializes in organic synthesis of API and offers expertise in synthesis design, process optimization, structural determination, derivative preparation, impurity preparation, compound characterization, and NMR.

C/Faraday, 7 Madrid, 28049 SpainQuosPharma specializes in organic synthesis of API and offers expertise in synthesis design, process optimization, structural determination, derivative preparation, impurity preparation, compound characterization, and NMR.

avenida de la comunidad valenciana Madrid, Madrid, 28760 SpainA Consultant and Business Development for: 1. DNA synthesis services a. Design and synthesize complex, long and highly variable sequences. 2. NGS space a. Service for WGS, RNAseq, Plasmid, antibody, variants, etc.. 3. RNA therapeutics a. Design, synthesis, market, regulatory landscape 4. Molecular Biology: a. Animal models, b. Gene Expression, c. Design of Experiments, d. Technical writing,

Avenida de la Comunidad Valenciana 17, P6-4B Tres Cantos, Comunidad de Madrid, 28760 SpainA Consultant and Business Development for: 1. DNA synthesis services a. Design and synthesize complex, long and highly variable sequences. 2. NGS space a. Service for WGS, RNAseq, Plasmid, antibody, variants, etc.. 3. RNA therapeutics a. Design, synthesis, market, regulatory landscape 4. Molecular Biology: a. Animal models, b. Gene Expression, c. Design of Experiments, d. Technical writing,

Hospital General Universitario Gregorio Maranon de MadridThe HIV Biobank was created in 2004 as a bank of biological samples, whose mission is to contribute to the advancement of scientific knowledge in HIV infection. To achieve this goal, HIV Biobank samples performs a regulated storage conditions to ensure their usefulness and future investigations that may arise as you advance knowledge of this disease.

Julián Camarillo, 35 Madrid, 28037 SpainRovi Contract Manufacturing (RoviCM) offers contract manufacturing services including aseptic filling, terminal sterilization, and safety device assembly.

Madrid, Community of Madrid SpainRovi Contract Manufacturing (RoviCM) offers contract manufacturing services including aseptic filling, terminal sterilization, and safety device assembly.

52 Calle de Claudio Coello 28001 Madrid, Comunidad de Madrid, 28001 SpainWe have a deep understanding of how government operates, the dynamics of large corporations, and the needs of startups. This knowledge is based on a team of highly regarded professionals, supported by a management team with extensive and distinguished experience in both the public and private sectors. Thanks to this, we are able to serve large organizations in various areas of innovation.

3 Calle Valle de Alcudia Las Rozas de Madrid, Comunidad de Madrid, 28232 SpainSeprotec is a global language solutions partner supporting regulated industries with translation, localization, interpreting, and multilingual content services. We help organizations manage complex international communication needs across life sciences, healthcare, legal, IP, and corporate environments, with a strong focus on quality, compliance, and scalability.

C/ Melchor Fernández Almagro, 3, E-28029 MadridThe CNIO Biobank is a cross-service platform for CNIO researchers and the general research community oriented towards the promotion of biomedical research in cancer and related diseases.

Avda. Ramón y Cajal, 103STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

Calle Torres Quevedo 15 Alcobendas, Madrid, 28108 SpainSynthelia Organics SL is a CRO focused on five pillars: - MedChem servicies - Development and optimization of synthetic routes of advanced intermediate / large-scale intermediates to speed up drug development in medical chemistry. - GMP like synthesis of compounds for preclinical assays. - Flow chemistry services ranging from the development of small-scale routes to the construction of production equipment. - Synthesis of gold nanoparticles functionalized with RNA.

C/Faraday, nº7, Lab. 2.05 España Madrid, Madrid, 28049 SpainSynthelia Organics SL is a CRO focused on five pillars: - MedChem servicies - Development and optimization of synthetic routes of advanced intermediate / large-scale intermediates to speed up drug development in medical chemistry. - GMP like synthesis of compounds for preclinical assays. - Flow chemistry services ranging from the development of small-scale routes to the construction of production equipment. - Synthesis of gold nanoparticles functionalized with RNA.

AVENIDA SUR AEROPUERTO BARAJAS 34, PLANTA 1, OFICINA 1 MADRID, MADRID, 28042 SpainWe accompany you in the integration and interpretation of data to improve decision making. We process clinical, image, genetic and personal data using Artificial Intelligence to improve healthcare and ultimately our lives. The quality and quantity of our data allows us to reduce bias and consequently provide more efficient and personalized responses to your needs.

Santibáñez de Béjar 3Telstar Life Science Solutions designs, manufactures, sell and support of high technology equipment solutions for the pharmaceutical, biotech and related industries

C/ Faraday 7 Madrid, Madrid, 28049 SpainThe Genomics Unit offers centralized research services and expert consultation in the vast fields of genomics and genetics. Our services span a wide range of applications, from conventional methods to the latest genomic technologies, helping to uncover biological complexities, identify therapeutic targets, and discover prognostic biomarkers. These advanced technologies can analyze entire genomes and their functions, revealing a full spectrum of structural and functional characteristics. Our facility works with state-of-the-art Next Generation Sequencing (NGS) systems, including the Illumina MiSeq, NextSeq, NovaSeq 6000 and NovaSeq X Plus Sequencing Systems. For single-cell approach with use the 10X Genomics Chromium X that allow us to work with fixed cells. Leveraging the advanced speed and throughput capabilities of these platforms, researchers can expedite their studies by conducting large-scale sequencing projects. We provide comprehensive analyses of nucleic acids purified from various sources such as snap-frozen tissues, FFPE samples, cell cultures, organoids, plasma, blood, stool, and a wide diversity of enviroments samples (soil, water, air). Our services are offered in both single-end and paired-end sequencing modes: Genome Sequencing: Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), and targeted enrichment sequencing. Transcriptome Sequencing: Total RNA-Seq and mRNA-Seq. Small Non-Coding RNA Analysis: miRNA-Seq. Genome-wide DNA Methylation Analysis: Methyl-Seq/BS-Seq and methylation array profiling. Single-Cell Genomic Applications: scRNA-Seq and Multiome. Spatial Transcriptomics. Genome-wide Location Analysis of Nucleic Acid-Protein Interactions: ChIP-Seq. At the Genomic Facility, we continually establish new protocols to handle challenging samples, including those with low input or poor quality (low RIN/DIN numbers) and metagenomic samples. In addition to our standard services, we offer customized solutions to meet your specific research needs.

Avenida de Madrid, 11Univ. of Granada Tissue Engineering Research Group focuses on histology research for therapeutic areas.

Calle de Santiago Grisolia 2 Tres Cantos, Madrid, 28760 SpainVivia offers pharmacological profiling and CDx/biomarker discovery services in patient samples to provide key information for drug development. We partner with drug developers throughout every stage of drug research and development with our proprietary PharmaFlow Technology Platform, from target discovery to biomarker discovery and companion diagnostic in clinical trials. We are working with more than 20 pharmaceutical and biotechnology companies worlwide to enable precision medicine driven therapies. PharmaFlow PM is a precision medicine platform to personalize the treatment of patients suffering Hematological Malignances. PharmaFlow PM generates clinically predictive data: patients predicted sensitive in 1st line show 92% CR at induction and 75% OS at 3-years* Vivia enables early identification of drug resistant clones to unleash targeted molecular biomarker discovery programs, uncovering the molecular basis of resistance of your drug. Vivia offers unique, state of the art, native environment immune-oncology and microenvironment assays. PharmaFlow PM CDx can deliver over 90% compelete remisión (CR) on your drug’s clinical trial. 92% CR 92% 75% OS 75% * Results from observational clinical trial with Pethema in Spain in 123 AML patients treated with first line Cytarabine and Idarubicin. Publication ready for early issuance. Vivia offers to its partners proprietary Native Environment Assays in patient’s whole bone marrow, assessing the drug activity in the native tumor microenvironment: Assays include state of the art immune-oncology (IO drugs, CAR-T), and microenvironment assays (BCR inhibtiors) Key deliveries of PharmaFlow PM for your drug development: Direct impact in ROI over 90% CR in clinical trials as CDx Identification of early molecular biomarkers of efficacy/resistance Better understanding of MOA & interpatient variability of response Best combos to incrase market share & overcome resistance in clinical trials Market positioning vs. SOC and competitive drugs Vivia can also enable fast deployment of Investigator Sponsored Trials with its European KOL network, where PharmaFlow PM would be used as CDx.

2 Calle de Santiago Grisolía Tres Cantos, Comunidad de Madrid, 28760 SpainVivia offers pharmacological profiling and CDx/biomarker discovery services in patient samples to provide key information for drug development. We partner with drug developers throughout every stage of drug research and development with our proprietary PharmaFlow Technology Platform, from target discovery to biomarker discovery and companion diagnostic in clinical trials. We are working with more than 20 pharmaceutical and biotechnology companies worlwide to enable precision medicine driven therapies. PharmaFlow PM is a precision medicine platform to personalize the treatment of patients suffering Hematological Malignances. PharmaFlow PM generates clinically predictive data: patients predicted sensitive in 1st line show 92% CR at induction and 75% OS at 3-years* Vivia enables early identification of drug resistant clones to unleash targeted molecular biomarker discovery programs, uncovering the molecular basis of resistance of your drug. Vivia offers unique, state of the art, native environment immune-oncology and microenvironment assays. PharmaFlow PM CDx can deliver over 90% compelete remisión (CR) on your drug’s clinical trial. 92% CR 92% 75% OS 75% * Results from observational clinical trial with Pethema in Spain in 123 AML patients treated with first line Cytarabine and Idarubicin. Publication ready for early issuance. Vivia offers to its partners proprietary Native Environment Assays in patient’s whole bone marrow, assessing the drug activity in the native tumor microenvironment: Assays include state of the art immune-oncology (IO drugs, CAR-T), and microenvironment assays (BCR inhibtiors) Key deliveries of PharmaFlow PM for your drug development: Direct impact in ROI over 90% CR in clinical trials as CDx Identification of early molecular biomarkers of efficacy/resistance Better understanding of MOA & interpatient variability of response Best combos to incrase market share & overcome resistance in clinical trials Market positioning vs. SOC and competitive drugs Vivia can also enable fast deployment of Investigator Sponsored Trials with its European KOL network, where PharmaFlow PM would be used as CDx.

C/Cerro de la Carrasqueta 63Zeptosens offers protein microarray profiling for biomarker discovery and validation, cell based screening, selectivity profiling and toxicology assessment.

Ronda de Valdecarrizo 41º B Tres Cantos 28760 SpainZF BioLabs offers genomic, toxicity and safety assay, and bioassay services using zebrafish as an alternative model of study.

Tres Cantos, Community of Madrid, 28760 SpainZF BioLabs offers genomic, toxicity and safety assay, and bioassay services using zebrafish as an alternative model of study.

Calle Gran Via 62, 4ºIzq – 28013 MadridZurko Research , since 2005, is offering to its clients a high-level technical support in the development of biotechnological solutions in the areas of health, food and agriculture and environment. But in the recent years, the company has adapted its strategy development according to the trends of current market needs in the sectors of health and personal care. Strong of its consulting experience in biotechnology, Zurko Research has decided to design and develop new added-value services for the healthcare industry and cosmetics. To this purpose the company has decided to create a specific department called Zurko Cosmetics and services aimed at testing cosmetic ingredients and products. The department consists of experts in pharmacy and cosmetic biotechnology with great experience in trial development both in vitro live.