R. Álvaro de Campos Nº18 1º Esq. 2675-225 ODIVELAS PortugalEstablished in 2002, the AgroFile is a leader in Portugal in conducting field trials for the biological evaluation of plant protection products as well as in the evaluation of various parameters of new seed varieties. With its main facilities located in the west and extensions / partnerships in Minho, Cova da Beira, Ribatejo, Alentejo and Algarve, Agrofile has the right conditions for an overall work at the national level, acting in all agricultural regions and hence all cultures and their problems. The peculiar Portuguese climate, conducive to the development of a range of insects and diseases in addition to a very diverse spontaneous flora, allows trials in obtaining reliable results, an important basis for building solid bilógicos dossiers and subsequent approval of products.

7 Rua Orfanato Escola Santa Isabel Rio de Mouro, Lisboa, 2635-047 Portugalhe passion for climate: how ARALAB was born In 1978, a 16 years old boy spent his summer holidays at his parents garden obsessed with creating a machine of hatching eggs with better performance than their own chickens. When the chicks were born healthy, and in half the time, we went to his father and said "Dad, I'm going to be the inventor of the world's best weathering machines". The little boy was João Araújo and 7 years later he founded ARALAB. The reference of quality in the Iberian Peninsula From 1985 to 2008 ARALAB consolidated itself as the partner of high precision climate with whom one can count, especially in Bio research, Pharmaceutical products and Testing segments for the industry. Aralab emerged as the market leader in Portugal and became a reference in Spain. World conquest The Iberian Peninsula was the beginning. In 2008, Joao and Eduardo invited their brother Alberto to lead the commercial department. The 3 brothers are together and the company they founded and named (Araújo + Lab) is no longer the small family business. It has projects in 32 countries and distributors in 5 continents. It is closer to the dream. And wants more.

Estrada da Quinta , 148 Manique de Baixo 2645 – 436 Alcabideche PortugalAzevedos offers manufacturing and development of pharmaceuticals.

Edifício ICAT, Campus da FCUL - Campo Grande 1749-016 Lisboa PORTUGALBioalvo offers HTS and drug research and development.

Av. Padre Cruz, 1649-016 LisbonThe National Health Institute Doutor Ricardo Jorge (INSA) is a public organization of the Ministry of Health, endowed with scientific, technical, administrative, financial and property of its own. Founded in 1899 by Ricardo Jorge (Porto, 1858 - Lisbon, 1939), as laboratory of the Portuguese Health System, INSA develops a triple role as State Laboratory in the Health Sector, National Reference Laboratory and National Health Observatory. INSA has operating units at its headquarters in Lisbon, two centers in Porto (Centre for Public Health Dr. Gonçalves Ferreira and Medical Center of Genetics Jacinto Magalhães) and Águas de Moura (Centre for Vectors and Infectious Diseases Dr. Francisco Cambournac). INSA is organized in technical and scientific terms, in six major departments: Food and Nutrition Department Infectious Diseases Department Epidemiology Department Human Genetics Departament Health Promotion and non Communicable Disease Prevention Environmental Health Department All operative units composing the departments develop multidisciplinary programmes in problem-areas of Public Health, namely performing R&D, health monitoring, training, laboratory external quality assessment and general health services. Led by a Board of Direction, composed by a president (Fernando de Almeida) and one other member (José Maria Albuquerque), INSA’s human resources sum over 600 people, more than half of them with a higher education degree, including 60 with a PhD or equivalent.

Avenida do Brasil Lisboa, P-1700-069 PortugalCBS Computational Biology Services offers computational biology and modeling services.

NOVA-CRU FCM/CEDOC – UNL Campo Mártires da Pátria, 130 1169-056 LISBOA PORTUGAL

Avenida Brasília, 1400-038 Lisbon, Portugal

Rua Fialho de Almeida N14 - 2 esq esc F2 Lisbon PortugalCirklo aims to offer a thorough solution for scientific facilities or shared resource laboratories. Our approach is based in 4 standpoints: 1) Optimization by having comprehensive resource booking schemes and products/service requisition flow control, automatized warnings, integrated mailing lists and comprehensive pricing settings 2) Accountability with financial reporting/invoicing, project based accounting, real vs schedulled usage and user access control 3) Monitoring so that managers know who and when, alarmistics, experimental conditions and safety 4) Quality control with incident tracking, service programming and reporting Nonetheless, our intention is to continue to to have a business model based on low structural costs against high service pricing, thus providing an affordable solution independently of the facility size.

Lisbon, Lisbon PortugalCirklo aims to offer a thorough solution for scientific facilities or shared resource laboratories. Our approach is based in 4 standpoints: 1) Optimization by having comprehensive resource booking schemes and products/service requisition flow control, automatized warnings, integrated mailing lists and comprehensive pricing settings 2) Accountability with financial reporting/invoicing, project based accounting, real vs schedulled usage and user access control 3) Monitoring so that managers know who and when, alarmistics, experimental conditions and safety 4) Quality control with incident tracking, service programming and reporting Nonetheless, our intention is to continue to to have a business model based on low structural costs against high service pricing, thus providing an affordable solution independently of the facility size.

Rua Almada Negreiros, Lote 5, Loja14, Alverca Do Ribatejo, 2615-275 PortugalCliniSciences is a European distributor of products & services from suppliers based all around the world. With a direct presence in 18 countries, CliniSciences serves customers through its own commercial and technical teams in Austria, Belgium, Denmark, Finland, France, Germany, Iceland, Ireland, Italy, the Netherlands, Norway, Poland, Portugal, Spain, Sweden, Switzerland, the United Kingdom, and the United States. Through these companies, CliniSciences offers a broad portfolio of life science reagents, instruments and services for research and diagnostic applications. Our product range includes reagents, antibodies, cells, assay kits, instruments, and a strong offering of human biological samples, including blood-derived products, tissues, primary cells, biofluids, DNA/RNA and other clinically relevant biospecimens. Our services include antibody development, peptide and protein synthesis, bulk manufacturing, humanization, custom production and other tailored solutions to support life science, biotech and diagnostic projects.

Rua Pedro Nunes Nº.20 – 7º Esquerdo Frente 2780-142 Oeiras PortugalDeallus provides offerings to support strategy development and decision making in life-science organizations.

6 Praceta Progresso Clube Algueirão-Mem Martins, Lisboa, 2725-076 PortugalEndobios Biotech launched this year the ENDOBIOS E-CHEM® service, a technology that allows you to profile the rare bioactive natural products in your extracts through its chemistry (turnaround 4-6 weeks). Specifically, we profile the bioactive secondary natural products directly in extracts through specialized untargeted metabolomics and matching their chemical fingerprinting properties with multiple natural products-related databases. ENDOBIOS E-CHEM® is a cost-effective analytics tool aimed to find functional values in bioproducts, for monetization at higher productivity levels (applicable to commercialized products, R&D bioassets or biowaste). Yet, ENDOBIOS E-CHEM® is a multipurpose tool: it can co-detect toxic natural products (potential liabilities), supports quality control of batches/providers, supports regulatory entry in new markets, diagnoses counterfeit or adulterated bioproducts, and much more, as it is customer-tailored. ENDOBIOS E-CHEM® aims to provide a competitive hedge to its client’s bioresources – from plants to algae, bacteria and fungi -, with science-based value propositions applied to cosmetics, agro or health. Our flyer: https://endobios.com/wp-content/uploads/2021/10/E-CHEM.pdf

Rua Tierno Galvan Torre 3, Piso 16 Lisboa, 1070-274 PortugalEurotrials, Scientific Consultants, is a privately owned company founded in Lisbon in 1995 by members of academia, medical community and pharmaceutical industry. It specializes in clinical research and scientific consultancy in the area of health and currently operates in Europe and Latin America. Eurotrials’ close collaboration with medical and regulatory institutions is an essential success factor that has been recognized by its partners, i.e. the pharmaceutical and international biotechnology industry, regulatory agencies, universities and clinical research centres., CROs and agro-food industry. The company’s success stands on pillars that have marked its personality since it was founded: creativity in finding solutions, unique technology, multidisciplinary expertise, solid experience and quality. It is qualified to participate in all the steps of any clinical, translational or epidemiological research project, from the initial research question to the final output. Eurotrials has a team of over 120 young, motivated employees and counts on diversity and interdisciplinarity to meet its customers’ needs. The team includes physicians, biologists, pharmacists, biostatisticians, sociologists, nutritionists, chemists, engineers, psychologists and mathematicians, among others.

Campo Grande Lisbon, 1749-016 PortugalThe mission of the Faculty of Sciences of the University of Lisbon is to expand the limits of scientific knowledge and technology, transfer this knowledge to society and promote the education of its students through the practice of research.

Rua João de Deus, nº 19 - Venda Nova 2700-487 Amadora PortugalGeneris Farmacêutica offers drug development and contract manufacturing for solid oral dosage forms.

Amadora, Lisbon PortugalGeneris Farmacêutica offers drug development and contract manufacturing for solid oral dosage forms.

Avenida Da República, Edf. Instalação Piloto Do Ibet, Quinta Do Marques Lisboa PortugalGenibet offers cell line development, process development, analytical development, and GMP production of recombinant proteins, DNA, viral, and cell products.

Rua da Quinta Grande Oeiras, Lisboa, 2780-156 PortugalIntroducing GIMM: Pioneering Research for Global Health GIMM (Gulbenkian Institute for Molecular Medicine) is a visionary merger between two esteemed institutions in Portugal: Instituto de Medicina Molecular João Lobo Antunes (iMM) and Instituto Gulbenkian de Ciência (IGC). Our mission is clear: to become a global leader in transdisciplinary research, unraveling life’s mysteries, and addressing global health challenges. Our Vision GIMM aims to pioneer groundbreaking research from fundamental discoveries to innovative healthcare solutions, with a profound impact on global health and wellbeing, fostering a vibrant scientific community that shapes the future of molecular medicine. GIMM will explore biology across scales, in space and time, from molecules to ecosystems, considering their interactions with the ever changing surrounding environments. Above all, we will always chase the thrill that is on the verge of discovery.

Avenida Professor Egas Moniz, Lisboa, Lisboa 1649-028, PTIntroducing GIMM: Pioneering Research for Global Health GIMM (Gulbenkian Institute for Molecular Medicine) is a visionary merger between two esteemed institutions in Portugal: Instituto de Medicina Molecular João Lobo Antunes (iMM) and Instituto Gulbenkian de Ciência (IGC). Our mission is clear: to become a global leader in transdisciplinary research, unraveling life’s mysteries, and addressing global health challenges. Our Vision GIMM aims to pioneer groundbreaking research from fundamental discoveries to innovative healthcare solutions, with a profound impact on global health and wellbeing, fostering a vibrant scientific community that shapes the future of molecular medicine. GIMM will explore biology across scales, in space and time, from molecules to ecosystems, considering their interactions with the ever changing surrounding environments. Above all, we will always chase the thrill that is on the verge of discovery.

2674-506 Loures PortugalHovione FarmaCiencia provides process chemistry, manufacturing, inhalation technologies, clinical supplies, and drug development.

Estrada de Alfragide Alfragide, Lisboa, 2610-011 PortugalHT has a team of 15 professionals, with wide experience in health sector, 85% of whom are health professionals. In addition to its internal workforce, HT has a network of more than one hundred healthcare professionals, distributed nationwide, which allows a rapid response at the local level. This team works, every day, to find the best solution corresponding to the demand for business with higher efficiency and profitability solutions, through the structure completely dedicated and committed to its customers and beneficiaries. Despite the organization's youthfulness, HT is a certified company ISO 9001:2015, ID 9108647776, by TUV. Human Talent operates as a service provider in healthcare industry, particularly in four key areas: • Design, implementation, and management of patient support programs for chronic illness and long-term therapy. • Project implementation and management, based on specialized outsourcing, with selection, recruitment, training, and project coordination of qualified teams. • Design and implementation of innovative promotional models, particularly in the areas of Digital Marketing. • Provide support in the field of Telemedicine, namely Teleassistance and Telemonitoring projects in partnership with Technological Companies

Barcarena, Lisboa, 2730-208 PortugalIBERFAR specializes in contract manufacturing, dedicated to the secondary pharmaceutical industry.

Rua de Moscavide Loja6D, Parque das Naçoes Lisbon, Portugal, 1990-160 PortugalThe INFOTOX is a consulting company specialized in the regulation of chemicals by providing technical support for the public and private sectors. Our services include technical support and independent advice in several areas: - Chemicals Regulation - Toxicology and Risk Assessment - Environmental health We conduct integrated, multidisciplinary and cost-effective risk assessments so our customers can meet their regulatory requirements and Product Management objectives.

Av. República - Quinta do Marquês 2784-505 Oeiras PortugalThe Analytical Services Unit (ASU) is a joint department of Instituto de Biologia Experimental e Tecnológica (IBET) and Instituto de Tecnologia Química e Biológica (ITQB-UNL) under the executive management of IBET. Services include analytical development, validation and testing of chemicals and biologicals as well as quality control and batch release of experimental and human medicines under Good Manufacturing Practices (GMP)

Oeiras, Lisbon PortugalThe Analytical Services Unit (ASU) is a joint department of Instituto de Biologia Experimental e Tecnológica (IBET) and Instituto de Tecnologia Química e Biológica (ITQB-UNL) under the executive management of IBET. Services include analytical development, validation and testing of chemicals and biologicals as well as quality control and batch release of experimental and human medicines under Good Manufacturing Practices (GMP)

Ponds Park Building 5, Tower C, Level 3 2740-298 Porto Salvo PortugalJaba Recordati specializes in therapeutic medications, manufacturing of medical devices and prescription and non prescription drugs.

Avenida Prof. Gama Pinto nº 2 Complexo Interdisciplinar da Universidade de Lisboa, Salas 2.12 – 2.14 Lisboa, Lisboa, 1649-003 PortugalNIMGenetics provides advanced Genomics, Transcriptomics, Bioinformatics and cell line characterization services leveraging NGS, Single-cell and arrayCGH technologies and expertise to support Biopharma Industry, CROs and Academic Researchers. With the recent purchase of Gene Predictis SA in Switzerland, we also include molecular microbiology analyses, polygenic risk scores development, genotyping platform & possibility to design custom genotyping arrays and validated based on our DNAtek, in vitro diagnostics development and pharmacogenetics At NIMGenetics, we pride ourselves on the Speed, Competitive Pricing and Tailored R&D Services we can offer our partners. Furthermore, NIMGenetics becomes the first human genetic diagnosis company in the world to be certified as a B Corp, thus accrediting its generation of positive social and environmental impact through its activity. We integrate the most modern technologies with an internally developed pipeline for genomic analysis, applying our own bioinformatics tools, Artificial Intelligence (AI), Machine Learning (ML) and a large proprietary genetic database. In addition, NIMGenetics’ Clinical Relationships, in Leading Hospitals and Clinics, as well as our Repository of Clinical Genomics Data, makes us an especially interesting partner to support R&D projects from the Earliest Discovery and Preclinical Stages to Clinical Trials and Companion Diagnostics (CDx). NIMGenetics offers Research and Development Support Services such as: Whole-Genome and Exome Sequencing, Gene Expression (RNASeq, Single Cell and Methylation Profiling), DNA-Encoded Chemical Libraries, Genomics for Cell and Gene Therapy, Optical Genome Mapping, CRISPR Off-target Effects, Viral Vector Integration Analysis, Bioinformatics Analysis, a growing Genomics Database of under-represented populations from the Iberian Peninsula and Latin America, and tailor-made R&D Consultancy projects. We support researchers in Oncology, Rare Diseases, Regenerative Medicine, Neurodevelopmental and Neurodegenerative Diseases, Gynecology and Reproductive Medicine, GastrointestinaI, Microbiome and a wealth of other Research Areas.

Estrada do Paço do LumiarNZYTech offers site directed mutagenesis, gene cloning and subcloning, gene synthesis, plasmid DNA preparation, protein production, and oligo synthesis services.

Campo Grande, 286 R/C Dto - 1700-096 Lisboa, PortugalPhD Trials is a Portuguese Contract Research Organization engaged into the clinical assessment of safety and efficacy of products for topical application (cosmetics, chemicals or food products). We are a multidisciplinary team of specialists boasting more than 15 years of experience in the scientific support to the national and international industry. We are the solution to the new challenge of cosmetic industry.

Alameda da Universidade Lisboa, Lisboa, 1649-014 PortugalPhD Trials is a Portuguese Contract Research Organization engaged into the clinical assessment of safety and efficacy of products for topical application (cosmetics, chemicals or food products). We are a multidisciplinary team of specialists boasting more than 15 years of experience in the scientific support to the national and international industry. We are the solution to the new challenge of cosmetic industry.

Rua Consiglieri Pedroso n.º123 edificio K 2.º piso Barcarena, Barcarena, 2734-501 PortugalRodon Biologics, CRO/CDMO based in Lisbon, Portugal, has more than 20 years experience in protein recombinant production and process development. Rodon is a spin-off of Biotecnol, operating in Portugal since 1996, dedicated to bioprocess development, upstream and downstream processes. Our customized and costumer-centric services include: protein production, analytical metod development, cell-based assays, cell line and process development. All projects are executed under a quality system. We are dedicated to build a flexible and close relationship with every company who works with us, since we believe it’s the only way to reach success for both parts.

Rua Martens Ferrão Lisboa, Lisboa, 1050-159 PortugalSICGEN antibodies is a biotechnology company specialized in the development and production of antibodies for research in life and health sciences. By taking full advantage of cutting-edge technologies SICGEN is committed to becoming a global provider of polyclonal antibodies and antibody-related products and services of the highest quality and at competitive prices. SICGEN continuously strive to develop new antibody-related products and services for applications in industry and research. Currently SICGEN produces custom polyclonal antibodies for leading national and international institutions, including universities, research institutes, pharmaceutical manufacturers and biotechnology distributors worldwide.

Avenida Professor Doutor Cavaco Silva, Edifício Tecnologia1.2, nº 21, Porto Salvo, Lisboa, 2740-257 PortugalSmartFreez delivers Cryoprocessing systems for optimal performance and time-to-market, ensuring safe and reliable biotherapeutics across the globe. SmartFreez develops innovative cryopreservation solutions for the biopharmaceutical industry, specializing in freezing and thawing systems for sensitive biologics like proteins, cell-based therapies, and viral vectors. With expertise in scientific research and advanced computational tools, including CFD-based simulations, we offer lab instruments, scale-down models, and scalable manufacturing solutions. Our technologies enhance the stability, viability, and yield of biologics, streamlining R&D and production contributing to significant cost reductions. Our trustworthy and flexible technology, empower scientific teams on their cryopreservation challenges while providing a costumizable and customer support-centric approach.

Madan Parque, Rua dos Inventores Salas 2.18 e 2.19 Caparica , 2825-182 PortugalSTAB VIDA supplies oligos, probes and offers Sanger DNA sequencing, NextGen Sequencing, Bacteria/Yeast identification and Paternity testing

Madan Parque, Rua dos Inventores Salas 2.18 e 2.19 Monte de Caparica, Setúbal 2825-182 PortugalSTAB VIDA supplies oligos, probes and offers Sanger DNA sequencing, NextGen Sequencing, Bacteria/Yeast identification and Paternity testing

Av. Antonio Serpa, n°32, 4C Lisboa, 1050-027 Portugaltebubio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

Edifício da BPU do iBET Av. da República Quinta do Marquês, Oeiras , 2780-157 PortugalVibalogics is a global contract development and manufacturing organization (CDMO) offering process and analytical development, manufacturing, testing, and fill-finish services to innovators developing revolutionary virotherapy products. We are an ambitious partner with a vision of leading the virotherapy CDMO market by pioneering efficient, economically viable, and GMP compliant manufacture of complex oncolytic viruses, viral vector gene therapies and vaccines, by enabling our customers to deliver transformational products to patients worldwide. Our industry-leading viral expertise supports your successful progress along the way and helps mitigate challenges frequently seen in this emerging segment of industry, and our comprehensive services support both clinical- and commercial-capability from initial technical transfer, GMP drug substance and drug product manufacture, to quality control batch release facilitating overall speed and security of our customer’s product supply chain. Partner with us and you will experience a transparent and consultative partnership. Our ethos of flexibility and open communication provides our customers with the resourceful and adaptable strategies they need to ensure projects are completed successfully, on budget and on time. Following an impressive track record in virotherapy manufacturing, in April 2022, Vibalogics was acquired by Recipharm AB, a leading Global CDMO. The acquisition of Vibalogics will expand Recipharm’s global business offering along with the company’s additional acquisitions which include GenIbet Biopharmaceuticals S.A. (Oeiras, Portugal) and Arranta Bio (Watertown, MA). Together, the companies will extend their services to the ATMP (advanced therapy medicinal products) market, through a robust end-to-end offering with capabilities spanning development, GMP drug substance and drug product manufacture, sterile fill & finish, and analytical and quality control testing.