118 Eldridge Rd, Suite C Sugar Land, TX, 77478 United StatesAbbexa is based at the World renowned Cambridge Science Park, in Cambridge, UK. We are a supplier and distributor of biological tools for the life science, pharmaceutical development and biotechnology sectors. We provide the scientific community with primary antibodies, secondary antibodies, proteins, ELISA kits and enzymes as well as other kits and tools for use in research. Working with various laboratories across the World, we aim to develop relevant, high quality, tested products for the biomedical research market. Abbexa is a dedicated worldwide antibody supplier and protein supplier. Whether you are carrying out academic research, pharmaceutical research, disease research or other biological research, our monoclonal antibodies, polyclonal antibodies, proteins and biological reagents are designed to facilitate your research. We appreciate that sometimes it is hard to find the right antibody to match your needs, and we therefore offer a custom protein, peptide and antibody production pipeline. Abbexa is committed to providing scientists and researchers with the best customer experience and high quality products. We want to provide you with the best support available, which is why we guarantee customer satisfaction. If you are unhappy with the performance of your product we will offer you an immediate replacement or refund. Please have a look at our quality guarantee for further details. We are constantly striving to improve in everything we do, so please do get in touch with any comments regarding the website, service, products, or anything else.

9330 Kirby Drive Houston, TX, 77054 United StatesAbblis Chemicals LLC ( http://www.abblis.com ) is one of the leading manufacturers and suppliers of high-performance specialty organic chemicals and chemical intermediates products for the non-clinical research fields in the global market, with expertise in custom reagents design and synthesis. With a full mix of professionals in chemistry research, QA/QC, and trade business, we're confident to satisfy dependable and sustainable sourcing demands. Abblis has facilities all over world. We have laboratories in the United States and manufacturing bases both in the States and in China. We specialized in supplying Organic Chemicals and also own an enthusiastic, energetic and friendly technical and customer support team and management team with years of experience in the Organic Chemical Industry. We also keep increasing our custom synthesis capabilities and providing faster delivery for bulk chemicals and are aiming to provide the most innovative range of research reagents at the most competitive price. Our samples include Building Blocks, Organoborons, Organohalides, Organosilanes, Reduction, Oxidation, Catalysts, Protections, Chiral Auxiliaries, Condensation Agents and etc. Abblis insure good quality of our product by NMR, HPLC, GC and so on. Unlike the other providers, Abblis always does the HPLC via 3 different HPLC conditions which can minimize the probable error. For chiral compounds, we also provide the chiral HPLC spectrum which can give the ee% value directly! At the same time, we have established a stable relationship with customers within engaged in laboratory and development chemist, universities, research institutions and government agencies for years.

Houston, TX United StatesAcademy Biomedical Company supplies high quality antibodies for the atherosclerosis research community.

1417 Kress Street Houston, TX 77020-7422 USAAcademy Biomedical Company supplies high quality antibodies for the atherosclerosis research community.

10165 Harwin Drive Suite 150 Houston, TX 77036Accutest Research Laboratories offers clinical trials, method development, pharmacokinetic analysis, BA/BE studies, and herbal medicine screening.

Gruss 1st Floor Overview The Gruss Magnetic Resonance Research Center (MRRC) is a multidisciplinary and multimodality (MRI and MicroPet/SPECT/CT) based research facility within Einstein that is dedicated for clinical and basic research. The center supports both human MR Imaging and Spectroscopy and animal MRI PET/SPECT and CT research, including structural, functional, physiological, molecular, spectroscopy and chemical shift imaging. The center is staffed by professionals with MRI and uPET technical, image analysis, clinical and technological expertise. The facility includes patient interview, preparation and recovery facilities and a full range of patient stimulus and monitoring technology.

3509 Elgin Street, Suite 300 Houston, TX, 77004 United States*Please Direct all requests to our parent company Discovery Life Sciences.* AllCells is the CGT brand of Discovery Life Sciences Featured: - GMP-compliant Leukopaks, GMP Bone Marrow, Mobilized Leukopaks, as well as Cryopreserved Leukopak products - Integrated network of HLA-typed donor pools located across the United States, in accordance with IRB, FDA, and AABB - Extensive research-use products and services & class A and B cleanroom capabilities - Bulk (full pak) cell isolations for cell banking or matched samples pre-clinical screening options for early-stage pipeline development Founded in 1998, AllCells is the global leader in the procurement and customization of biologically relevant research and GMP-compliant products and donor management services to support a diversity of life sciences applications. AllCells’ FDA-registered facilities, robust quality framework and proven industry expertise afford the responsiveness, product diversity, quality and regulatory standards required by researchers in life sciences. Our donor facilities - located in California, Massachusetts, Alabama, and Texas - and GMP-compliant cleanroom are strategically located, enabling immediate processing and cryopreservation for unparalleled quality. AllCells provides flexible and scalable solutions to support dynamic, client-specific needs and timelines from inception to commercialization. AllCells – Quality Cells for Quality AllCells also provides Clinical Grade products for further manufacturing of allogeneic cell based therapies. Through our experience in GMP Allogeneic Clinical Grade collections, we have developed a proven approach to delivering the highest level of quality and compliance.

10450 Stancliff Road Suite 210 Houston, TX 77099ALS Global services support food and pharmaceutical quality assurance, environmental monitoring, mining and mineral exploration, commodity certification, equipment maintenance, and industrial operations.

12521 Gulf Freeway Houston, TX 77034 USAAM Biotechnologies develops DNA-based affinity agents called thioaptamers using unique chemistries and a proprietary bead-based selection process.

12521 Gulf Freeway, Houston, Texas 77034

10301 NW Freeway Ste. 408 Houston, Texas, 77092 United StatesAmerra is a dynamic medical communications company that develops 3D animation and innovative educational & training applications. We leverage the latest cutting-edge solutions to effectively communicate complex information, including device demonstrations, surgical techniques, and mechanisms of action (MoAs), to a broad range of audiences.

10301 NW Freeway Ste. 408 Houston, TX, 77092 United StatesAmerra is a dynamic medical communications company that develops 3D animation and innovative educational & training applications. We leverage the latest cutting-edge solutions to effectively communicate complex information, including device demonstrations, surgical techniques, and mechanisms of action (MoAs), to a broad range of audiences.

Houston, TX United StatesApexbio Technology LLC is a premier provider of small molecule inhibitors/activators, compound libraries, peptides and assay kits. We can also supply fluorescent dyes, various enzymes, modified nucleotides and further mRNA synthesis service for molecular biology research. With industry leading research/development/manufacturing abilities, we keep bringing advanced research reagents for scientists across the globe. For more product info, please visit www.apexbt.com

7505 Fannin Street, Suite 410 Houston, TX, 77054 United StatesApexbio Technology LLC is a premier provider of small molecule inhibitors/activators, compound libraries, peptides and assay kits. We can also supply fluorescent dyes, various enzymes, modified nucleotides and further mRNA synthesis service for molecular biology research. With industry leading research/development/manufacturing abilities, we keep bringing advanced research reagents for scientists across the globe. For more product info, please visit www.apexbt.com

7505 Fannin Street, Suite 410 Houston, Texas, 77054 United StatesApexbio Technology LLC is a premier provider of small molecule inhibitors/activators, compound libraries, peptides and assay kits. We can also supply fluorescent dyes, various enzymes, modified nucleotides and further mRNA synthesis service for molecular biology research. With industry leading research/development/manufacturing abilities, we keep bringing advanced research reagents for scientists across the globe. For more product info, please visit www.apexbt.com

9420 London Bridge Station Houston, TX 77054 USAApexbio Technology LLC is a premier provider of small molecule inhibitors/activators, compound libraries, peptides and assay kits. We can also supply fluorescent dyes, various enzymes, modified nucleotides and further mRNA synthesis service for molecular biology research. With industry leading research/development/manufacturing abilities, we keep bringing advanced research reagents for scientists across the globe. For more product info, please visit www.apexbt.com

2575 West Bellfort, Suite 190 Houston, TX 77054ApoCell offers biomarker, assay, microarray, antibody, cell analysis, and protein expression services.

Houston, TX United StatesApoCell offers biomarker, assay, microarray, antibody, cell analysis, and protein expression services.

10555 Turtlewood CT Houston,TX 77072 USAAQSIQ laboratory boasts the ability to issue (GB-CHINA) Laboratory certificates to companies and individuals exporting food and feed products to the Republic of CHINA. AQSIQ laboratory in 2002 became the first official laboratory to be approved by the China Food & Drug Administration to test for pesticide residues and Food Microbiology, this scope was broadened in 2009 to include testing and certification in the fields of nutrition, food supplements, and Food Chemistry Analysis. The benefit of AQSIQ laboratory ‘s scope of accreditation are more security: Exporters can now rest assured that their cargo will be accepted at china ports of entry because AQSIQ standards have been met, China consumers will have peace of mind knowing that their food products are safe and compliant with china food labeling standards, AQSIQ laboratory issued of test report with chinese version will be recognized in every port of China CIQ.

1415 S. Voss Road, Suite 110-465 United States Houston, TX, 77057 United StatesAqumin developed AlphaVision® for medical software, a unique data analysis solution that offers a better/faster way to analyze data without missing vital information or wasting time on dead ends. We provide large scale data aggregation using high-performance 3D visualization. Users are able to combine and re-arrange large, complex datasets from multiple sources in real-time for instant pattern recognition of complex relationships. Fast, interactive hypothesis testing answers questions in minutes instead of weeks. Installations of our software (in genomic oncology) show early success. We are currently partnering with large cancer research organizations on workflows that speed up their drug and treatment development to get them to patients them in less time. We are ready for rapid market expansion. Our mission is to make this game changing technology readily available to the medical/pharmaceutical industry for better and faster data analysis saving time and money in research and development. See Everything, Miss Nothing®

7255 Helix Park Ave Houston, TX, 77030 United StatesArtidis® is a pioneering clinical stage health technology company that aims to set the gold standard in tissue analysis and therapy optimization. By combining its AFM-based nanotechnology platform for rapid tissue analysis with a holistic data solution, Artidis® accelerates drug discovery, tissue engineering, and personalized treatment. Artidis® focuses its research and development efforts on solid tumors to enhance responses to chemo, immuno, and cell therapies, driving precision in cancer care. The company has offices in Basel (Switzerland), Barcelona (Spain), and Houston (Texas, US). Traditional AFM (atomic force microscopy) workflows are plagued by low usability, long measurement times, complex sample and tip preparation, manual calibration steps, and large user dependent variability of results, resulting in slow, error-prone processes. Artidis® transforms this experience, bringing next-level, precision AFM to any laboratory and setting a new standard for reliable, high throughput nanomechanical phenotyping.

25500 Westheimer Parkway Suite 7207 Katy, TX, 77494 United StatesAUC Solutions offers comprehensive consulting and CRO services for scientists studying nanoscale molecules in the solution phase by analytical ultracentrifugation to solve problems in biochemistry, biophysics, structural biology, material science, polymer science and related areas of physical sciences. We provide support to scientists worldwide to help with sample analysis, experimental design, protocol development, and data analysis of analytical ultracentrifugation experiments. Our products and services include unrivaled analysis software, high-performance computing infrastructure suitable for modeling AUC experiments. Through our laboratory we provide detailed hydrodynamic characterization for your nanoscale products, including pharmaceutical formulations, protein and nucleic acid systems, antibodies, nanoparticles and other colloidal materials in need of solution characterization. We work with your team to develop a sound analysis protocol and measurement plan to achieve a high-resolution characterization for your samples. We provide training, tutorials and hands-on workshops to decrease the learning curve for mastering arcane biophysical techniques and provide software to assist with high-resolution analysis and high-throughput processing.

2450 Holcombe Boulevard Suite X Houston, TX, 77021 United StatesBiobank and custom biospecimen procurement CRO collecting tissue, blood, biofluids, and other specimens from a wide variety of disease areas including oncology, ophthalmology, immunology, and normal controls. We maximize the impact of every patient's donation by focusing on delivering high-quality human biospecimens tailored to your project’s specific needs. Biospecimens that make a difference.

5500 NW Central Drive Houston , TX, 77092 United StatesAvance Biosciences is a premier Contract Research Organization (CRO) and Contract Testing Organization (CTO) providing CGMP/GLP-compliant analytical and bioanalytical solutions to advance the development and manufacturing of drugs and biologics. We can support your method development, pre-clinical and clinical studies, CMC testing, diagnostics development, and CLIA-certified testing needs. Leveraging expertise in genomics, cell biology, microbiology, immunoassays, and analytical chemistry, Avance Biosciences provides comprehensive services encompassing assay development, validation, and sample testing. Our comprehensive analytical and bioanalytical methods make use of advanced technologies to provide potency assays, on/off target testing, biodistribution assays, CAR-T and other cell therapy testing, cell bank testing, RNA therapeutics analysis, and more.

7030 Empire Central Dr Houston, TX, 77040 3214 United StatesAvance Biosciences is a premier Contract Research Organization (CRO) and Contract Testing Organization (CTO) providing CGMP/GLP-compliant analytical and bioanalytical solutions to advance the development and manufacturing of drugs and biologics. We can support your method development, pre-clinical and clinical studies, CMC testing, diagnostics development, and CLIA-certified testing needs. Leveraging expertise in genomics, cell biology, microbiology, immunoassays, and analytical chemistry, Avance Biosciences provides comprehensive services encompassing assay development, validation, and sample testing. Our comprehensive analytical and bioanalytical methods make use of advanced technologies to provide potency assays, on/off target testing, biodistribution assays, CAR-T and other cell therapy testing, cell bank testing, RNA therapeutics analysis, and more.

9770 W Little York Rd Houston, TX, 77040 United StatesAvance Biosciences is a premier Contract Research Organization (CRO) and Contract Testing Organization (CTO) providing CGMP/GLP-compliant analytical and bioanalytical solutions to advance the development and manufacturing of drugs and biologics. We can support your method development, pre-clinical and clinical studies, CMC testing, diagnostics development, and CLIA-certified testing needs. Leveraging expertise in genomics, cell biology, microbiology, immunoassays, and analytical chemistry, Avance Biosciences provides comprehensive services encompassing assay development, validation, and sample testing. Our comprehensive analytical and bioanalytical methods make use of advanced technologies to provide potency assays, on/off target testing, biodistribution assays, CAR-T and other cell therapy testing, cell bank testing, RNA therapeutics analysis, and more.

8619 Broadway St. Suite 100 Pearland, TX, 77584 United StatesBase Pair Biotechnologies, Inc. offers rapid discovery of high quality aptamer affinity ligands. Aptamers have been successfully employed in virtually every application where antibodies are typically used. Aptamers have a number of potential advantages over antibodies, however, in a variety of applications. For more information, please visit http://www.basepairbio.com/

One Baylor Plaza Taub Building, Suite T130 Houston, TX 77030The Bioengineering Core provides scientific instrumentation resources that catalyze the success of investigators by providing them with tools needed to design elegant experiments and ask truly cutting-edge research questions. BEC services include: Customized scientific instrumentation design Customized scientific instrumentation manufacture Customized electronics/optics design Customized electronics/optics manufacture 3D design and printing

Michael E. DeBakey Center One Baylor Plaza, Room 904G Houston, TX 77030The CDD is a resource for investigators in all Baylor College of Medicine departments and will complement efforts in the Department of Pharmacology, the Gulf Coast Consortia, and the Institute for Clinical and Translational Research as well as other departments and centers at Baylor College of Medicine. The CDD is integral to the Experimental Therapeutics initiative at BCM. The CDD includes a state-of-the-art screening facility to perform screening for a wide range of cell-based phenotypic and target-based biochemical assays in high-throughput or follow-up screens. This vital resource will work closely with BCM scientists to develop and perform primary screens. Once assays have been validated with small drug libraries, larger screens can be performed with the help of the Gulf Coast Consortia. Secondary validation assays and additional assays with newly synthesized analogs will also be performed in the center.

One Baylor Plaza Suite S104 Houston, TX 77030The Core for Advanced Magnetic Resonance Imaging (CAMRI) is a state-of-the-art resource for the Houston research community that makes possible advanced imaging studies of the function, physiology and anatomy of animals and humans. The center houses three cutting edge imaging systems: Two Siemens Magnetom Trio Scanners (3T) with VB 17 software One Siemens Magnetom Trio Scanner (3T) with 32 Channel capabilities Our systems are equipped for advanced high resolution structural imaging, diffusion tensor imaging (DTI), functional MRI, Arterial Spin Labeling (ASL) and single and multi-voxel magnetic resonance spectroscopy (MRS). They also contain auditory, visual and gustatory stimulation systems.

One Baylor Plaza Houston, TX 77030Baylor College of Medicine Dan L. Duncan Cancer Center offers histology, pathology, tissue acquisition and microarray services.

Alkek Research Building - R507/R551C Baylor College of Medicine One Baylor Plaza Houston, TX 77030Services Recombinant Protein Expression (Baculovirus System) & Hybridoma/Monoclonal Antibody Production

BCM-Alkek Building Room: N630 Houston, TX 77030The Genetically Engineered Mouse (GEM) Core serves as a central core facility for the generation, importation and storage of these mouse models. This saves valuable resources and allows investigators to focus their efforts on the molecular and physiologic analysis of their mouse models. Information provided on our site informs Baylor researchers about the services provided by the GEM core and how to contact the GEM Core to schedule these services.

Baylor College of Medicine One Baylor Plaza - Room 325E Houston, TX, 77030 United StatesBaylor College of Medicine Genomic and RNA Profiling Core or GARP (formerly the Microarray Core Facility) provides researchers access to state-of-the-art molecular profiling technology and services.

One Baylor Plaza Mail Stop BCM505 Houston, TX 77030The Human Stem Cell Core provides a wide range of products and services related to human pluripotent stem cell research, as well as hands-on training classes for basic and advanced stem cell culture techniques. The HSCC offers cost-effective solutions to generate and characterize novel induced pluripotent stem (iPS) cells for in vitro disease modeling, employing “zero-footprint” technologies such as Sendai virus-based and episomal vector-based reprogramming. We also offer customized research support for experimental design and validation assays.

Jones Building, Room 150E Baylor College of Medicine One Baylor Plaza Houston, TX 77030This is a unique proteomic service that provides antibody affinity purification of endogenous protein complexes and MS-based identification and analysis of the associated proteins. Suitable antibodies for immunoprecipitation of the desired protein complex and optimization of the cell line, culture conditions and methods for cell lysis and antibody affinity purification are provided as services. The complexes are isolated under conditions of cellular activation by appropriate signals as requested by the cancer center investigator. Services Isolation and Identification of Protein Complexes Identification of Post-Transcriptional Modifications Data Analysis

Alkek Center for Molecular Discovery First Floor, Jewish Building Baylor College of Medicine One Baylor Plaza - BCM107C-115C Houston, TX 77030The Metabolomics Core at Baylor College of Medicine is an analytical facility specializing in liquid chromatography hyphenated with mass spectrometry techniques. Its main role is to support investigators in their research in the study of metabolism, as well as understanding of the mechanisms of particular cancer states, which will ideally lead to earlier detection and better treatments. The core has established methods for targeted measurement of over 500 metabolites, metabolic flux, and drug metabolism and pharmacokinetics (DMPK) in diverse biological specimens using established protocols, methods and mass spectrometry as the primary platform. Procedurally, the core personnel perform extraction of metabolites from biological samples using a combination of aqueous and organic solvents, carry out the mass spectrometry analysis, and pre-process the mass spectral data. The entire process starting from sample preparation to mass spectrometry is monitored using spiked isotopic standards that have been characterized for their chromatographic behavior and fragmentation profile. Once the mass spectral data is obtained, various data analytics steps namely scaling, imputation and normalization are performed using Mass Hunter software and the resulting output is passed on to an in-house biostatistics pipeline, that then computes the data to determine metabolite levels, and define differential compounds. This Tier 1 level of data analysis is provided as part of routine Core service. Upon request, additional advanced Tier 2 level data analysis can be provided separately by our bioinformatics group. Tier 2 analysis can include pathway mapping using multiple enrichment methods that include Oncomine Concept Map (OCM), Ingenuity (IPA), Gene Set Analysis (GSA), and Network-based Gene Set Enrichment Analysis (NETGSEA). Tier 2 data analysis can also support integration of transcriptomic and proteomic data (if available with the investigator) with the metabolomics data.

One Baylor Plaza - BCM227 Houston, TX 77030Advanced technologies are used at the Mouse ES Cell Core Facility to generate genetically engineered mice needed by researchers across the United States who are in pursuit of answers and cures for human disease. Our facility serves to assist investigators with projects that involve generating mutations in the germ line and somatic tissues of mice by performing homologous recombination in ES cells. The procedures for the manipulation of ES cells and the construction of mice are intensive and technically demanding and it is a goal of the core to make such experiments possible for investigators.

Children’s Nutrition Research Center 1100 Bates St., 1st Floor Houston, TX 77030The primary goal of the Mouse Metabolic Research Unit is to characterize mouse metabolic phenotypes. MMRU users currently have access to a Comprehensive Laboratory Animal Monitoring System (CLAMS, Columbus Instruments) for metabolic assessments, and the PIXImus and QMR instruments for indirectly estimating body composition; i.e., lean body mass, fat mass, and bone mineral content.

Ben Taub Basement – T001 Houston, TX 77030The Mouse Phenotyping Core is one of the most comprehensive Phenotyping Cores in the United States. We occupy a 3,400-square-foot space dedicated to enhance research at the Baylor College of Medicine. We provide investigators with state-of-the-art equipment for the identification and study of mouse models of human disease and drug studies. The core establishes protocols for the phenotyping of these mouse models. Promotion of educational opportunities for students and post docs is our mission. We also strive to generate collegiality between investigators and faculty/trainees from cores and centers. The MPC is located within an AALAC accredited animal facility on the main Baylor campus. The facility includes non-invasive testing and imaging equipment, a dedicated surgical suite, several surgical services, animal housing, administrative and technical staff offices, and a data analysis workstation area. We have a full-time director and two laboratory technicians on staff to assist you. The MPC is available to all investigators at Baylor and outside institutions and we stand to promote educational opportunities for students and post docs.

One Baylor Plaza Cullen Building (112 A, 114 A) Smith Building (S 403) Houston, TX 77030The Optical Imaging and Vital Microscopy Core provides cutting-edge imaging and image analysis tools for researchers in all branches of science and engineering. We strongly encourage interdisciplinary collaborations from Baylor College of Medicine community and from around the world.

Alkek Building for Biomedical Research 5th Floor, Suite R531E Baylor College of Medicine One Baylor Plaza Houston, TX 77030The Population Sciences Biorepository (PSB) was created to support a high-quality molecular epidemiology program in the Dan L. Duncan Cancer Center and across Baylor College of Medicine. We also serve as a scientific resource for investigators on biospecimen collection and storage methods in their efforts to discover etiologic risk factors and deliver personalized medicine. Our goal is to provide necessary risk factor and clinical data collection and a centralized, cost-effective facility for biospecimen processing and storage of biospecimens from large epidemiological and clinical studies. The PSB provides services for individually funded investigators as well as for clinical centers wishing to bank specimens prospectively from their patients for future research projects. The PSB clinical coordinators can assist with consenting, phlebotomy, and data collection, if needed. The PSB Laboratory provides full fractionation and aliquoting for blood and urine samples, as well as DNA extraction from whole blood, buffy coat, or saliva. Our team can consult with you to plan the data and specimen collection and storage needs for your projects. The PSB has an ongoing recruitment protocol that recruits patients with the diagnoses listed in the table below. If you would like to develop a project using these samples, please contact the PSB director to learn about availability and the process for accessing these specimens.

One Baylor Plaza, Jewish Building 130D Houston, TX 77030Service and Expertise Multiplex quantitative analyses using the suspension array system (Bio-plex from Bio-Rad) through Luminex xMAP bead technology. Assays include: Cytokines, adipokines, & growth factors Intracellular signaling pathways Protein phosphorylation Protein Profiling for Biomarker Discovery and Differential Expression Two dimensional liquid chromatography for patient serum/plasma samples, solid tumors, and cultured cells. Depletion of IgG and albumin from serum samples to enrich low abundant proteins.

One Baylor Plaza - Room N1409 Houston, TX 77030The Single Cell Genomics Core provides comprehensive services for DNA and RNA profiling on single or a small number of cells. The core is equipped with the C1 auto cell prep, HD Biomark, and Access Array platform. Combination of these platforms allows cost-effective and high throughput DNA and RNA profiling ranging from a set of genes to the entire genome.

2450 Holcombe Blvd Houston, TX, 77021 United StatesFor 45 years, Baylor Genetics has been the leading pioneer in genetic testing. We offer a full spectrum of cost-effective, genetic testing and provide clinically relevant solutions to our customers. Our team’s unmatched knowledge and experience deliver a combination of advanced technology and deep patient data sets that lead to more accurate interpretations.

2 Greenway Plaza, STE 910 Houston, TX 77046BCM Technologies’ (BCMT) investment strategy revolves around the concept that maximum returns from early stage life science investing will result from impeccable diligence and a solid understanding of the underlying science. BCMT likes to invest early and create substantial value by leveraging the experience of the team to guide the company through the start-up process and avoid common mistakes. Success at such an early stage requires constant rationalization of investments and extreme discipline to focus on the likely winners. “BCMT brings business acumen to company development: seasoned CEOs; venture capital; and management expertise to jump start opportunities for faculty.” –Dr. Paul Klotman, President and CEO of Baylor College of Medicine Company Creation BCMT is a true “early-stage investor” that provides seed capital to perform value creating proof-of-concept research and plays a major role in the structuring and development of the start-up company. The initial investment from BCMT is often made for the specific goal of validating the technology through highly focused research activities and initial investment frequently precedes recruitment of a management team. BCMT prefers to lead Seed and First rounds and will continue to co-invest in later rounds. Our Commitment With proven success in identifying, protecting and commercializing innovative technologies from academic institutions, pharmaceutical companies, and other sources, we seek unique technologies with solid intellectual property positions.

19901 Southwest Freeway Sugar Land, TX 77479-6538 USABioCentra offers custom peptide synthesis, antibody production, antigen design, and protein analysis services.

13313 Southwest Fwy Ste 192C Sugar Land, 77478 Texas USABioMeans offers custom DNA cloning, DNA preparation and DNA mutagenesis services.

7505 Fannin St Houston, TX, 77054 1913 United StatesBiostate: Cost-Effective RNA & Exome Sequencing at Scale Biostate is a multi-omics and artificial intelligence company specializing in high-throughput RNA Sequencing and next-generation Exome Sequencing to power discovery, translational research, and precision medicine. Built on patented wetlab chemistries (BIRT, PERD, MARE) and a global wetlab footprint, Biostate AI delivers large-scale, high-fidelity transcriptomic and genomic data at substantially reduced cost, enabling projects that were previously not feasible in terms of budget or scale. Our flagship Total RNA Sequencing service comprehensively captures both coding and non-coding RNA species, including lncRNA, miRNA, circRNA and enhancer RNA, going beyond traditional gene expression profiling that focuses only on mRNA. This chemistry is tightly integrated with Biostate’s AI platforms (OmicsWeb Copilot), providing end-to-end workflows from library prep and sequencing through interactive, AI-assisted bioinformatics for biomarker discovery, mechanism-of-action studies, drug response prediction, and disease stratification. In 2025, Biostate expanded its platform to Whole Exome Sequencing (WES), leveraging the same proven wetlab and automation stack that has delivered tens of thousands of RNA-seq libraries. The WES service is designed for research groups that need robust variant detection in coding regions, with >95% coverage at 30× (average ~100×), excellent performance on FFPE, dried blood spots, and other challenging or low-input DNA samples (≥10 ng), and seamless integration into K-Dense for AI-driven variant interpretation and cohort-level analyses. Key Services: Total RNA Sequencing - Whole-transcriptome profiling of coding and non-coding RNA - Suitable for discovery, mechanism-of-action, and AI model training RNA Sequencing (RNA-seq) / Gene Expression Analysis - Bulk RNA-seq for differential expression, pathway analysis, and longitudinal studies - Resequencing of existing cohorts to harmonize data for AI/ML pipelines Exome Sequencing / Whole Exome Sequencing (WES) - High-depth coding region interrogation for germline or somatic variant discovery - Optimized for challenging samples (FFPE, low-input, dried blood spots) Capabilities & Advantages: - Integrated omics + AI stack: sequencing, QC, and AI-driven analysis (OmicsWeb Copilot) - Patented chemistries enabling cost-efficient, large-scale RNA Sequencing and Exome Sequencing - Support for human and major preclinical species - Flexible project structures: pilot studies, grant-supported academic projects, and pharma-scale cohorts - Dedicated scientific support for study design, bioinformatics, and downstream interpretation

6919 Almeda Rd Houston, TX 77021Who We Are Bryan Laboratory, Inc. consists of a quality assurance/inspection group, metallurgical laboratory, materials testing laboratory, chemical laboratory, metallographic laboratory and a machine shop for specimen preparation. Each of these groups interact closely to support the needs of our clients. What We Do We provide clients with a comprehensive range of material testing services. Our state-of-the-art facilities metallurgical evaluations, as well as failure analysis of industrial equipment and products manufactured from ferrous and nonferrous alloys.

1111 Texas 6 Sugar Land, TX, 77478 United States

1111 HWY 6 South, Suite 150 Sugar Land, TX 77478

1110 NASA Parkway, Suite 502 Houston, TX 77058In 2011, NASA chose the Center for the Advancement of Science in Space (CASIS) to be the sole manager of the International Space Station U.S. National Laboratory. The mission of CASIS is to maximize use of this unparalleled platform for innovation, which can benefit all humankind and inspire a new generation to look to the stars. The organization has been awarded by NASA the responsibility of inciting the imagination of entrepreneurs and scientists alike, accelerating and facilitating space-based research as well as creating public awareness of National Lab research and making space science more accessible to the world. By carefully selecting research and funding projects, by connecting investors looking for opportunity to scientists with great ideas, and by making access to the station faster and easier, CASIS will drive scientific inquiry toward developing groundbreaking new technologies and products that will tangibly affect our lives.

5000 Gulf Freeway Building 4, Rm 118 Houston, Texas [TX], 77023 United StatesCellChorus provides high throughput, dynamic analysis of single cells. The company’s TIMING™ platform applies visual AI to evaluate cell activation, killing and movement as a function of time in order to maximize our understanding of cellular function, state and phenotype.

351 Columbia Memorial Prky., Ste. C-2 Kemah, TX, 77565-3234 United StatesCell Systems 3-D designs and engineers in vitro 3-D multitissue models from human, veterinary and insect primary cells. Because of the manditory State "stay-in-place" directive, Cell Systems-3D, LLC has suspended daily operation till at least May 15, 2020. All employee's are observing this stay-in- place directive, if we are able to resume operations on/about May 15, 2020 we will still non-operation for at 2 additional weeks to clean and prepare the laboratory for in vitro cell culture. As May 15, 2020 approaches, I will leave updated messages within this box. Michael Suderman, MSc. President & Chief Science Officer Cell Systems-3D, LLC

20320 Northwest Freeway Suite 700 Houston, TX 77065 USACenter for Clinical Studies offers clinical research services.

305 Almeda Genoa Road Houston, TX, 77047 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

305 Almeda Genoa Road Houston, Texas, 77047 United StatesFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

4106 Merrick Street Houston, TX, 77025 United StatesChiron Clinical Communications is a full‑suite medical communications agency specializing in strategic, scientific, and creative solutions for pharmaceutical and medical device companies. Our integrated team—spanning scientific strategy, medical writing, creative design, account management, and editorial services—delivers high‑impact medical affairs and commercial assets that educate, engage, and empower healthcare audiences. From scientific platforms and publication support to branding, launch materials, and omnichannel campaigns, we bring scientific rigor and creative excellence together to move brands forward with clarity and credibility.

6811 Hawkins St Manvel, TX, 77578 United StatesClinicaGen Bio LLC is a clinician-founded network of multispecialty practices dedicated to biospecimen research including custom prospective collection, scheduled diagnostic remnant retention and prototype R/D in-vitro diagnostic instrument hosting. We have taken the regulatory burden off the client by designing a unique biospecimen collection protocol with ICFs and waiver of informed consent for diagnostic remnants which all have current IRB approval. We have experienced clinical source facilities in 9 states ready to fulfill your collection request in Gynecology, Neurology, Psychiatry, Pulmonology, Internal/Family Medicine, Pediatrics, Dermatology, Podiatry, Cardiology, Endocrinology, Infections Disease/Immunology, Pain Management, or Ophthalmology. Our services are specific to fresh collections and do not include banked samples at this time. We also offer consulting services to industry and researchers which highlight US clinical operations as it relates to biospecimen collections to provide insight into timelines, patient populations, insurance considerations and other factors that influence studies.

23603 W. Fernhurst Dr., Unit 2201 Katy, TX, 77494 United States

11271 Richmond Avenue Suite H104, Houston, TX 77082, USA

Houston, TX, USAComsys provides IT staffing services.

Houston, TX United States

7707 Fannin St Ste.200 Houston, TX 77054 Houston, Texas, 77054 United StatesWe offer both catalog and customized Elisa Kits, Recombinant Proteins, and Antibodies, and also offer the following services. Recombinant Protein Expression Service Custom Antibody Production Service CUSABIO Therapeutic Antibody Discovery Service Stable Cell Line Development Service Peptide Synthesis Service Oligo Synthesis Services Gene Synthesis Services

7505 Fannin St., Ste 610, Room 7, Houston, TX, 77054 United StatesWe offer both catalog and customized Elisa Kits, Recombinant Proteins, and Antibodies, and also offer the following services. Recombinant Protein Expression Service Custom Antibody Production Service CUSABIO Therapeutic Antibody Discovery Service Stable Cell Line Development Service Peptide Synthesis Service Oligo Synthesis Services Gene Synthesis Services

7505 Fannin St Ste 610-322 Houston, TX, 77054 United StatesWe offer both catalog and customized Elisa Kits, Recombinant Proteins, and Antibodies, and also offer the following services. Recombinant Protein Expression Service Custom Antibody Production Service CUSABIO Therapeutic Antibody Discovery Service Stable Cell Line Development Service Peptide Synthesis Service Oligo Synthesis Services Gene Synthesis Services

7707 Fannin St Ste.200 Houston, TX 77054 Houston, TX, 77054 United StatesWe offer both catalog and customized Elisa Kits, Recombinant Proteins, and Antibodies, and also offer the following services. Recombinant Protein Expression Service Custom Antibody Production Service CUSABIO Therapeutic Antibody Discovery Service Stable Cell Line Development Service Peptide Synthesis Service Oligo Synthesis Services Gene Synthesis Services

7505 Fannin St Ste 610-322 Houston, Texas, 77054 United StatesWe offer both catalog and customized Elisa Kits, Recombinant Proteins, and Antibodies, and also offer the following services. Recombinant Protein Expression Service Custom Antibody Production Service CUSABIO Therapeutic Antibody Discovery Service Stable Cell Line Development Service Peptide Synthesis Service Oligo Synthesis Services Gene Synthesis Services

One Baylor Plaza Room 247E, MS BCM 280 Houston, TX, 77030 United States

6850 Wynnwood Ln. Houston, TX 77008 USADewalch Life Technologies provides a full range of molecular biology services, including (but not limited to) nucleic acid extraction and purification, DNA sequencing, cloning, and crop seed purity test for research projects.

2450 Holcombe Boulevard Suite BCMA Houston, TX, 77021 United StatesDiversigen is a fee-for-service company, providing CLIA/CAP certified and GLP compliant microbiome profiling services. From pre-project consulting, sample handling to the application of various sequencing/Bioinformatics pipelines and delivery of data analysis, we can help you make sense of the microbiome. Capabilities: -16S/ITS2/18S analysis -Metagenomics - Whole Genome Sequencing -Strain/Species qPCR development -MetaTranscriptomics – RNAseq -Virome analysis -Single Genome Sequencing

1 Baylor Plaza Houston, TX, 77030 United StatesDiversigen is a fee-for-service company, providing CLIA/CAP certified and GLP compliant microbiome profiling services. From pre-project consulting, sample handling to the application of various sequencing/Bioinformatics pipelines and delivery of data analysis, we can help you make sense of the microbiome. Capabilities: -16S/ITS2/18S analysis -Metagenomics - Whole Genome Sequencing -Strain/Species qPCR development -MetaTranscriptomics – RNAseq -Virome analysis -Single Genome Sequencing

9940 W. Sam Houston Pkwy S., Suite 310, Houston, Texas 77099

13201 Northwest Fwy. • Ste. 800 Houston, TX 77040e-Foods Imports is a Texas corporation that specializes in eliminating insects and microbial pathogens from fruits, vegetables, and other foods using the eBeam Pasteurization technology. This technology is able to add value to fresh fruits and vegetables, spices, seasonings, meats and shell eggs without the use of chemicals, antibiotics, and without leaving any residuals. The technology has been approved by the United States Food and Drug Administration (FDA) and USDA. Fruits processed by eBeam technology ripens slower, stays firmer and retains flavor qualities.

7505 Fannin St., Ste 200 Houston, Texas, 77054 United StatesEMPIRI provides valuable support for drug discovery companies through its E-Slice assay, a novel, 3D tumor tissue culture platform that maintains the complexity and integrity of individual cancer patient’s tumor outside of the body, providing the best model to empirically test which drugs are most effective for that patient. E-slice is unique in that it maintains the native tumor microenvironment - including immune cells - unique to each cancer to faithfully recapitulate patient therapeutic responses. It can be used to enhance both preclinical drug discovery and development efforts and clinical diagnosis. EMPIRI is also a trusted 10X Genomics Certified Service Provider, delivering end-to-end or a la carte single-cell sequencing services. Our services cover tissue dissociation, basic bioinformatics analysis, and everything in between, enabling us to provide high-quality single-cell RNA sequencing from samples such as 18-gauge biopsy cores obtained from clinical trial samples. Our expertise in single-cell sequencing has proven to be instrumental in maximizing the information gained during clinical trials and other important scientific research.

7505 Fannin St., Ste 200 Houston, TX, 77054 United StatesEMPIRI provides valuable support for drug discovery companies through its E-Slice assay, a novel, 3D tumor tissue culture platform that maintains the complexity and integrity of individual cancer patient’s tumor outside of the body, providing the best model to empirically test which drugs are most effective for that patient. E-slice is unique in that it maintains the native tumor microenvironment - including immune cells - unique to each cancer to faithfully recapitulate patient therapeutic responses. It can be used to enhance both preclinical drug discovery and development efforts and clinical diagnosis. EMPIRI is also a trusted 10X Genomics Certified Service Provider, delivering end-to-end or a la carte single-cell sequencing services. Our services cover tissue dissociation, basic bioinformatics analysis, and everything in between, enabling us to provide high-quality single-cell RNA sequencing from samples such as 18-gauge biopsy cores obtained from clinical trial samples. Our expertise in single-cell sequencing has proven to be instrumental in maximizing the information gained during clinical trials and other important scientific research.

1271 Rayford Bend Spring, TX, 77386 United StatesEPI Materials Testing Group is a multi-faceted materials testing and failure analysis laboratory. We have experience in a broad range of materials, from hard-facing and PCD inserts, to ferrous and non-ferrous alloys. EPI-MTG provides services from sample preparation, analytical testing, and wear/abrasion testing along with the capabilities, knowledge, and experience to get your job done.

13310 S. Gessner Road Missouri City, TX, 77489 United StatesEpoch Life Science offers nucleic acid purification, custom gene synthesis, protein expression, mutagenesis, and cloning services.

1306 FM-1092 Suite 407 Missouri City, TX 77459 USAEpoch Life Science offers nucleic acid purification, custom gene synthesis, protein expression, mutagenesis, and cloning services.

6387 Windfern Road Houston, TX 77040

410 Pierce Street, Ste 114 Houston, TX 77002Eureka Genomics offers nucleic acid detection, gene annotation, and sequencing services.

Deer Park, TX, USAExpertTox provides spectrometry, microscopy, DNA analysis, supplement analysis, and testing services.

Deer Park, TX United StatesExpertTox provides spectrometry, microscopy, DNA analysis, supplement analysis, and testing services.

The Woodlands, TX, USAExternal Pharma provides CNS indications for gene families, behavioral phenotyping, genetically modified mice lines, preclinical testing, and biomarkers.

1415 Hankamer st Pasadena, TX, 77506 United StatesEzerski Scientific provides a wide range of computational pipeline and platform design services for predictive analysis using ML/AI, bioinformatics, experimental deconvolution, MD simulation and more. We specialize in the following pharmaceutical applications: RNAi/oligonucleotide, proteins, ligand binding & small molecule, and custom algorithm development.

Houston, TX, USAFinoric specializes in manufacturing and distributing inorganic chemicals, flavors and fragrances, rare earth chemicals, and organic compounds.

9999 Veterans Memorial Drive Houston, TX 77038Fisher Scientific is dedicated to making the world healthier, cleaner, and safer, by providing laboratory essentials as well as solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. The Fisher Scientific channel is your one-stop shop for a variety of global product and service brands, offering a comprehensive selection of laboratory equipment, chemicals, instruments, biological products, and consumable supplies. With an extensive list of exclusive alliances with major manufacturers and our own Fisherbrand™ line of products, we provide easy access to the items that are most in demand—all from one source.

25043 West FM 1097 Montgomery, TX, 77356 United StatesFortis partners with diagnostics and life sciences companies to design, validate, and manufacture solutions to solve your complex development problems. At Fortis, we understand the impact scientific discovery has on society and how it affects people and human health. Therefore, we think about the effect your work has on the world every single day. Great products are everywhere. Yet, somewhere between the rapid advancement of science and technology, our industry lost something important. We lost the ease of connecting and the simplicity of getting the answers you need, when you need them. We are committed to developing reagents of the highest quality standards so your work continues with maximum integrity. But this is just our first step. Our products are backed by strong and knowledgeable customer and technical support. So, whether you prefer a digital self-service experience or connecting with us live, we promise reliable, responsive services to collaboratively support your success. It is our promise to ensure that every click, every purchase, and every interaction with Fortis brings you one step closer to discovery and brings us one step closer to a healthier world. Powered by our brands: Bethyl Laboratories, nanoComposix, Empirical Bioscience, Arista Biologicals, Abcore, iPOC

5401 Mitchelldale, Suite A-3 Houston, TX 77092

301 University Blvd. Galveston, Texas 77550Galveston National Laboratory offers in vivo imaging services.

Galveston, TX United StatesGalveston National Laboratory offers in vivo imaging services.

1445 North Loop West, Suite 820 Houston, TX 77008

Houston, TX USAGenetiVision offers DNA preparation, injection, and transgenic fly models.

16115 Park Row Suite 190 Houston, TX, 77079 United StatesGenome Explorations, a Tesis Biosciences company, offers CLIA and GLP certified clinical molecular research services including mRNA, miRNA expression, next generation sequencing services including; RNASeq/ Exon sequencing, de-novo whole genome, exome, transcriptome and targeted sequencing panels, Real-time PCR services including; SNPgenotyping, gene expression, copy number analysis. microarray services, liquid biopsies, cfDNA analyses, tumor profiling and more. Lab testing employing DMET and CytoScan arrays is also offered along with Ampliseq cancer gene sequencing. Genome Explorations also offers biomarker discovery services, pharmacogenomics and pharmacogenetics.

6621 Fannin Street Houston, TX, 77030 United StatesThe Heart Center Tissue Bank (HCTB) at Texas Children's Hospital is the largest pediatric tissue bank in the Texas Medical Center and houses a variety of tissue samples of patients with congenital heart defects. Our mission is to advance the research of congenital heart defects by fostering research collaborations with investigators not only within Texas Children’s Hospital, but globally. Heart Center Tissue Bank (HCTB) prospectively collects and banks surgical samples obtained from patients undergoing surgical treatment for congenital or acquired heart defects as an infrastructure for the advancement of basic and translational research in pediatrics.

6161 Savoy Drive Suite 1018 Houston, TX, 77036 United StatesHopstem provides human neural progenitor cells, cortical neurons, and motor neurons that are derived from iPSC, as well as human 3D brain organoids that are similar in size, shape, cell compositions, and structures, and are available in either 96 wells or 384 wells, which are ideal for toxicity and drug screening purposes. Hopstem also provides customized services including neurons differentiation, 3D organoids differentiation, and assays using MEA (Axion Bioscience) and high-content imaging system (PE Operetta). With our expertise in stem cell and CNS diseases, we could also work with you to customize and develop new readouts for your specific needs.

Houston, Texes United StatesAt Houston Methodist, our Advanced Cellular and Tissue Microscopy Core is staffed by experienced professionals who provide assistance with experimental design, specimen preparation, advanced microscope imaging techniques and complex imaging processing software for quantitative data analysis of cell biology and tissue pathology samples. We will help troubleshoot and optimize experiments to ensure the highest quality data is acquired. We specialize in various forms of wide-field imaging, high-resolution laser scanning confocal microscopy, living cell imaging systems and high-content screening systems.

Houston, Texas USAAt Houston Methodist, our Advanced Cellular and Tissue Microscopy Core is staffed by experienced professionals who provide assistance with experimental design, specimen preparation, advanced microscope imaging techniques and complex imaging processing software for quantitative data analysis of cell biology and tissue pathology samples. We will help troubleshoot and optimize experiments to ensure the highest quality data is acquired. We specialize in various forms of wide-field imaging, high-resolution laser scanning confocal microscopy, living cell imaging systems and high-content screening systems.

6565 Fannin Street Houston, TX 77030The experienced professionals in the Biomicrofluidics Core at Houston Methodist are experts in biomicrofluidic chip design and fabrication. The core creates custom designed microfluidic molds and chips, fabricates pre-made biomicrofluidic chips and provides consultation services for biomicrofluidics projects. Some of the pre-made chips include the V- and M-chips and chips that perform single-cell analysis and cell separation. Specialized Services The Biomicrofluidics Core offers several specialized services including consultation services for building your own microfluidic chips and fabrication of the following: Custom designed replica molds used for soft lithography Custom designed microfluidic PDMS/Glass chips Pre-made microfluidic chips: -V-chip -Single-cell analysis chip -Cell separation chip -Single-cell pipet tip Equipment OAI model 200 Mask Aligner Self-built UV exposure system Nikon Eclipse LV 100ND microscope Plasma Etch PE50 and Harrick plasma cleaners Thermoscientific Super-Nuova single-position digital stirring hotplates Dongda engraving machine Schmidt Tech holes puncher

6565 Fannin Street Houston, , TX , 77030 United StatesThe experienced professionals in the Biomicrofluidics Core at Houston Methodist are experts in biomicrofluidic chip design and fabrication. The core creates custom designed microfluidic molds and chips, fabricates pre-made biomicrofluidic chips and provides consultation services for biomicrofluidics projects. Some of the pre-made chips include the V- and M-chips and chips that perform single-cell analysis and cell separation. Specialized Services The Biomicrofluidics Core offers several specialized services including consultation services for building your own microfluidic chips and fabrication of the following: Custom designed replica molds used for soft lithography Custom designed microfluidic PDMS/Glass chips Pre-made microfluidic chips: -V-chip -Single-cell analysis chip -Cell separation chip -Single-cell pipet tip Equipment OAI model 200 Mask Aligner Self-built UV exposure system Nikon Eclipse LV 100ND microscope Plasma Etch PE50 and Harrick plasma cleaners Thermoscientific Super-Nuova single-position digital stirring hotplates Dongda engraving machine Schmidt Tech holes puncher

6565 Fannin Street Houston, , TX, 77030 United StatesThe experienced professionals in the Biomicrofluidics Core at Houston Methodist are experts in biomicrofluidic chip design and fabrication. The core creates custom designed microfluidic molds and chips, fabricates pre-made biomicrofluidic chips and provides consultation services for biomicrofluidics projects. Some of the pre-made chips include the V- and M-chips and chips that perform single-cell analysis and cell separation. Specialized Services The Biomicrofluidics Core offers several specialized services including consultation services for building your own microfluidic chips and fabrication of the following: Custom designed replica molds used for soft lithography Custom designed microfluidic PDMS/Glass chips Pre-made microfluidic chips: -V-chip -Single-cell analysis chip -Cell separation chip -Single-cell pipet tip Equipment OAI model 200 Mask Aligner Self-built UV exposure system Nikon Eclipse LV 100ND microscope Plasma Etch PE50 and Harrick plasma cleaners Thermoscientific Super-Nuova single-position digital stirring hotplates Dongda engraving machine Schmidt Tech holes puncher

6565 Fannin Street Houston,, TX, 77030 United StatesThe Biorepository Core at Houston Methodist is a large, general-purpose sample bank of solid tissue samples, blood, serum, plasma and other body fluids for use by Houston Methodist researchers and collaborators. We store solid tissue samples for various diseases, including cancers, and samples of blood, serum, plasma and other body fluids, in both in-house and off-site secure facilities. We also maintain legacy collections of cell lines, cells from diagnostic flow and HLA assays and extracted DNA samples. Besides our collection services, we offer processing and storage services that meet individual specific research protocols. We also maintain a database of basic clinical data elements for all samples in the repository and we provide round-the-clock monitoring of our storage facilities. In conjunction with the Research Pathology Core, we deliver paraffin embedding, immunohistochemical, hematoxylin and Eosin staining and pathology review services. All sample collection activities are conducted in a manner that ensures patient confidentiality, accurate pathologic annotation, and high ethical standards before, during, and after sample collection. Services: Collection, processing, and storage of samples per current global bio-banking standards Research protocol specific collection, shipping, and record keeping Maintenance of a database with basic clinical data elements for all samples Round-the-clock monitoring of freezers with adequate backup and disaster recovery protocols in place

6565 Fannin Street Houston, TX 77030The Biorepository Core at Houston Methodist is a large, general-purpose sample bank of solid tissue samples, blood, serum, plasma and other body fluids for use by Houston Methodist researchers and collaborators. We store solid tissue samples for various diseases, including cancers, and samples of blood, serum, plasma and other body fluids, in both in-house and off-site secure facilities. We also maintain legacy collections of cell lines, cells from diagnostic flow and HLA assays and extracted DNA samples. Besides our collection services, we offer processing and storage services that meet individual specific research protocols. We also maintain a database of basic clinical data elements for all samples in the repository and we provide round-the-clock monitoring of our storage facilities. In conjunction with the Research Pathology Core, we deliver paraffin embedding, immunohistochemical, hematoxylin and Eosin staining and pathology review services. All sample collection activities are conducted in a manner that ensures patient confidentiality, accurate pathologic annotation, and high ethical standards before, during, and after sample collection. Services: Collection, processing, and storage of samples per current global bio-banking standards Research protocol specific collection, shipping, and record keeping Maintenance of a database with basic clinical data elements for all samples Round-the-clock monitoring of freezers with adequate backup and disaster recovery protocols in place

6565 Fannin Street Houston,, TX, 77030 United StatesAt the Houston Methodist Biostatistics Core, we provide statistical analysis, data management and high performance computing services to internal and external research teams. Our core is a fee-for-service facility that consults on study design and analyses for grant- and contract-supported investigative research teams and clinical research groups. Our staff — who together hold more than 50 years experience in statistical analysis, mathematics, computation and data management — participate in grants, contracts, teaching and private consultations. We offer help in the areas of: Study design and conceptualization Data collection, storage/retrieval, and warehousing Sample size determination and statistical power Percentage points for discrete and continuous probability distributions (Binomial, Poisson, Standard Normal, Student’s t, F-ratio, Laplace, Skew-Normal, Logistic, etc.) Monte Carlo simulation and uncertainty analysis Inferential hypothesis testing Linear models (ANOVA, ANACOVA, MANOVA, and regression) Categorical modeling (log-linear, linear categorical, regression, and logistic regression) Univariate and multivariate regression modeling and diagnostics Survival and propensity scoring analysis Longitudinal data analysis (GLM, GEE, and RMANOVA) Bioinformatics (microarray QC, normalization, gene profile identification, cluster, and heat maps) Data mining

6565 Fannin Street Houston, TX 77030At the Houston Methodist Biostatistics Core, we provide statistical analysis, data management and high performance computing services to internal and external research teams. Our core is a fee-for-service facility that consults on study design and analyses for grant- and contract-supported investigative research teams and clinical research groups. Our staff — who together hold more than 50 years experience in statistical analysis, mathematics, computation and data management — participate in grants, contracts, teaching and private consultations. We offer help in the areas of: Study design and conceptualization Data collection, storage/retrieval, and warehousing Sample size determination and statistical power Percentage points for discrete and continuous probability distributions (Binomial, Poisson, Standard Normal, Student’s t, F-ratio, Laplace, Skew-Normal, Logistic, etc.) Monte Carlo simulation and uncertainty analysis Inferential hypothesis testing Linear models (ANOVA, ANACOVA, MANOVA, and regression) Categorical modeling (log-linear, linear categorical, regression, and logistic regression) Univariate and multivariate regression modeling and diagnostics Survival and propensity scoring analysis Longitudinal data analysis (GLM, GEE, and RMANOVA) Bioinformatics (microarray QC, normalization, gene profile identification, cluster, and heat maps) Data mining

6565 Fannin Street Houston, TX 77030At Houston Methodist’s Intravital Microscopy Core our expert and experienced research professionals master state-of-the-art imaging and image analysis tools to achieve in vivo advanced descriptive imaging and quantitative data analysis. The core is equipped with a single- and multi-photon confocal microscope with the fastest resonant scanner on the market, multiple laser sources and detectors that allows simultaneous image caption of four different fluorophores or contrast mechanisms, including second harmonic generation. Intravital Microscopy Image Core staff is able to provide custom designed experiment, training, creative imaging and image analysis solutions of various tissues and organs (including skin, liver, brain, spline, ear, intestine, muscle, pancreas, lymph nodes, and solid tumors). By implanting a window chamber (dorsal, abdominal and brain), the dynamics of therapeutic agents, micro- and nano-particles, and biological changes occurring locally can be observed in real-time for weeks. Moreover, to provide better statistic and take into account tissue heterogeneity, image or video acquisition can be iteratively automated over multiple fields of view and collected for short and long term (min-days).

6565 Fannin Street Houston,, TX, 77030 United StatesAt Houston Methodist’s Intravital Microscopy Core our expert and experienced research professionals master state-of-the-art imaging and image analysis tools to achieve in vivo advanced descriptive imaging and quantitative data analysis. The core is equipped with a single- and multi-photon confocal microscope with the fastest resonant scanner on the market, multiple laser sources and detectors that allows simultaneous image caption of four different fluorophores or contrast mechanisms, including second harmonic generation. Intravital Microscopy Image Core staff is able to provide custom designed experiment, training, creative imaging and image analysis solutions of various tissues and organs (including skin, liver, brain, spline, ear, intestine, muscle, pancreas, lymph nodes, and solid tumors). By implanting a window chamber (dorsal, abdominal and brain), the dynamics of therapeutic agents, micro- and nano-particles, and biological changes occurring locally can be observed in real-time for weeks. Moreover, to provide better statistic and take into account tissue heterogeneity, image or video acquisition can be iteratively automated over multiple fields of view and collected for short and long term (min-days).

10003 Woodloch Forest Drive The Woodlands, TX 77380 USAHuntsman is a global manufacturer and marketer of differentiated chemicals. Our operating companies manufacture products for a variety of global industries, including chemicals, plastics, automotive, aviation, textiles, footwear, paints and coatings, construction, technology, agriculture, health care, detergent, personal care, furniture, appliances and packaging. Originally known for pioneering innovations in packaging and, later, for rapid and integrated growth in petrochemicals, Huntsman has approximately 15,000 employees and operates from multiple locations worldwide. The Company had 2015 revenues of over $10 billion.

10003 Woodloch Forest Drive The Woodlands, , TX , 77380 United StatesHuntsman is a global manufacturer and marketer of differentiated chemicals. Our operating companies manufacture products for a variety of global industries, including chemicals, plastics, automotive, aviation, textiles, footwear, paints and coatings, construction, technology, agriculture, health care, detergent, personal care, furniture, appliances and packaging. Originally known for pioneering innovations in packaging and, later, for rapid and integrated growth in petrochemicals, Huntsman has approximately 15,000 employees and operates from multiple locations worldwide. The Company had 2015 revenues of over $10 billion.

10003 Woodloch Forest Drive The Woodlands, , TX, 77380 United StatesHuntsman is a global manufacturer and marketer of differentiated chemicals. Our operating companies manufacture products for a variety of global industries, including chemicals, plastics, automotive, aviation, textiles, footwear, paints and coatings, construction, technology, agriculture, health care, detergent, personal care, furniture, appliances and packaging. Originally known for pioneering innovations in packaging and, later, for rapid and integrated growth in petrochemicals, Huntsman has approximately 15,000 employees and operates from multiple locations worldwide. The Company had 2015 revenues of over $10 billion.

FM Rd 2917 P.O. Box 711 Alvin, TX 77512 USAHuntsman is a global manufacturer and marketer of differentiated chemicals. Our operating companies manufacture products for a variety of global industries, including chemicals, plastics, automotive, aviation, textiles, footwear, paints and coatings, construction, technology, agriculture, health care, detergent, personal care, furniture, appliances and packaging. Originally known for pioneering innovations in packaging and, later, for rapid and integrated growth in petrochemicals, Huntsman has approximately 15,000 employees and operates from multiple locations worldwide. The Company had 2015 revenues of over $10 billion.

8600 Gosling Road The Woodlands, TX 77381 USAHuntsman is a global manufacturer and marketer of differentiated chemicals. Our operating companies manufacture products for a variety of global industries, including chemicals, plastics, automotive, aviation, textiles, footwear, paints and coatings, construction, technology, agriculture, health care, detergent, personal care, furniture, appliances and packaging. Originally known for pioneering innovations in packaging and, later, for rapid and integrated growth in petrochemicals, Huntsman has approximately 15,000 employees and operates from multiple locations worldwide. The Company had 2015 revenues of over $10 billion.

2710 Reed Rd, Ste 160 Houston, TX, 77051 United StatesK2bio is a hybrid Contract Research Organization, offering our partners the option to conduct their own research studies in our bio-accelerator facility or contract our industry-experienced scientists to design and execute studies on their behalf. Our unique bench to commercialization model closes the gap between preclinical studies and clinical application. K2bio services includes GLP and non-GLP in vivo and in vitro support, analytical development, research and development support, and scale up for product commercialization, all tailored to client needs and goals. We offer a flexible suite of services to help our partners transition today’s scientific discovery into tomorrow’s therapies by creating efficiencies in early-stage development and navigating barriers to maximize productivity and minimize R&D spending.

4823 Katy Hockley Road Katy, Texas 77493Laboratory Mechanical Services is a specialty service company for laboratory and research facilities providing; design, construction, installation, and ongoing facility support of new and existing laboratories. The officers and employees of Laboratory Mechanical Services have many years of experience encompassing all aspects of the expertise to provide your laboratory’s specific requirements. We can provide planning and design services critical at the early stages of project conception which eliminates the need for costly changes during the construction phase. Services include but not limited to specialty plumbing, piping, acid, chemical and biological waste drain systems, instrument gas service tubing, exhaust systems, HVAC, laboratory furniture, remodels and renovations. Laboratory Mechanical Services provides the key elements of design, construction and installation for your laboratory in the Gulf Coast Region. Primary customers include refineries, chemical plants, universities, independent testing laboratories, hospitals, scientific manufacturers and general contractors. Safety is a major concern of the laboratory industry. Laboratory Mechanical Services recognizes that this industry desires to provide the highest level of security and safety for its clients. We can provide as a service to the industry, all necessary and required OSHA1910.1450, ANSI/AIHA Z9.5 mandated testing for the operation of fume exhaust equipment and NSF 49 for biological safety enclosures along with ASHRAE-110-1995 standard testing and certification of fume hoods. Our team has the training, expertise and equipment necessary to fulfill OSHA requirements for safety and will provide the testing and maintenance along with the records needed to document an ongoing safety effort.

Houston, TX United StatesLC Sciences is a global biotechnology company providing products and services to genomics and proteomics researchers across an array of markets for nucleic acid/protein analysis, biomarker-discovery and drug development. We offer proteomics, microarray, gene expression profiling, detection, and RNA / DNA sequencing services.

2575 West Bellfort StreetLC Sciences is a global biotechnology company providing products and services to genomics and proteomics researchers across an array of markets for nucleic acid/protein analysis, biomarker-discovery and drug development. We offer proteomics, microarray, gene expression profiling, detection, and RNA / DNA sequencing services.

1 Baylor Plz Breast Center Proteomics Lab 150E Houston, TX, 77030 3498 United StatesLocated at the heart of the Texas Medical Center, the largest medical complex in the world, Baylor College of Medicine focuses the efforts of faculty, staff and trainees on improving health through science, scholarship and innovation. This vision is realized through collaborative research initiatives in which basic, translational, and clinical researchers work together across disciplines and specialties to discover fundamental insights into human health and disease and to apply their discoveries to develop new diagnostic tools and treatments. Collectively the research engines on the TMC campus are number two in nation funding from the National Institutes of Health. Researchers collaborate across institutions creating a vast biomedical research ecosystem.

1 Baylor Plz Houston, TX, 77030 3498 United StatesLocated at the heart of the Texas Medical Center, the largest medical complex in the world, Baylor College of Medicine focuses the efforts of faculty, staff and trainees on improving health through science, scholarship and innovation. This vision is realized through collaborative research initiatives in which basic, translational, and clinical researchers work together across disciplines and specialties to discover fundamental insights into human health and disease and to apply their discoveries to develop new diagnostic tools and treatments. Collectively the research engines on the TMC campus are number two in nation funding from the National Institutes of Health. Researchers collaborate across institutions creating a vast biomedical research ecosystem.

8800 Technology Forest Place The Woodlands TX 77381-1160 USALexicon Pharmaceuticals provides gene knockout and human clinical trials.

8066 El Rio Street, Houston, TX, 77054 USALonza is one of the world’s largest contract development and manufacturing organizations (CDMOs) dedicated to serving the healthcare industry. Working across five continents, our colleagues work alongside pharma and biotech companies to turn their breakthrough innovations into viable therapies. We support our customers in bringing life-saving and life-enhancing treatments to patients worldwide with a combination of cutting-edge science, smart technology and lean manufacturing.

2 miles West of FM 2917 on FM 2004 Alvin, TX 77511 United StatesLyondellBasell (NYSE: LYB) is one of the world's largest plastics, chemical and refining companies and a member of the S&P 500. LyondellBasell manufactures products at 57 sites in 18 countries. LyondellBasell products and technologies are used to make items that improve the quality of life for people around the world including packaging, electronics, automotive parts, home furnishings, construction materials and biofuels.

2 miles West of FM 2917 on FM 2004 Alvin, TX, 77511 United StatesLyondellBasell (NYSE: LYB) is one of the world's largest plastics, chemical and refining companies and a member of the S&P 500. LyondellBasell manufactures products at 57 sites in 18 countries. LyondellBasell products and technologies are used to make items that improve the quality of life for people around the world including packaging, electronics, automotive parts, home furnishings, construction materials and biofuels.

1719 Park Forest Drive Katy, TX, 77450 United States Medical Mobile Service is your healthcare assistant to faster services. We provide on-site diagnostic services coming to you for lab service needs. We draw patients for clinical testing, providing shipping and processing services with after hour services. In addition, to taking vital signs. We assist small business, large collections, private companies, nursing homes, personal services, doctor offices and much more.

Houston, TX United StatesMedSource offers clinical monitoring, project management, regulatory affairs, clinical trial management, and quality assurance services.

11920 Westheimer Rd Houston, TX, 77077 6666 United StatesProspective Biospecimen Collection & Translational Research Partner Mercury Clinical Research, Inc. is a U.S.-based, multi-specialty clinical research organization specializing in prospective, IRB-governed biospecimen collection embedded within active therapeutic clinics. Our integrated site model enables customized sample procurement aligned with sponsor-specific protocols, inclusion criteria, and defined timepoints. Rather than relying on legacy stored inventories, we focus on protocol-driven, real-time sample collection, ensuring high-quality, clinically annotated specimens collected under controlled conditions with full chain-of-custody documentation.

1415 Highway 6 Sugar Land, TX, 77478-4952 United StatesProspective Biospecimen Collection & Translational Research Partner Mercury Clinical Research, Inc. is a U.S.-based, multi-specialty clinical research organization specializing in prospective, IRB-governed biospecimen collection embedded within active therapeutic clinics. Our integrated site model enables customized sample procurement aligned with sponsor-specific protocols, inclusion criteria, and defined timepoints. Rather than relying on legacy stored inventories, we focus on protocol-driven, real-time sample collection, ensuring high-quality, clinically annotated specimens collected under controlled conditions with full chain-of-custody documentation.

1328 S LOOP W SUITE 200 Houston, TX, 77054 United StatesProspective Biospecimen Collection & Translational Research Partner Mercury Clinical Research, Inc. is a U.S.-based, multi-specialty clinical research organization specializing in prospective, IRB-governed biospecimen collection embedded within active therapeutic clinics. Our integrated site model enables customized sample procurement aligned with sponsor-specific protocols, inclusion criteria, and defined timepoints. Rather than relying on legacy stored inventories, we focus on protocol-driven, real-time sample collection, ensuring high-quality, clinically annotated specimens collected under controlled conditions with full chain-of-custody documentation.

2 Greenway Plaza Houston, TX, 77046 United StatesMetanome provides solutions for sequencing, analysis, and consulting services geared toward the study of the microbiome of living organisms and environments.

2002 Holcombe Blvd Houston, TX 77030The Michael E. DeBakey VA Medical Center serves as the primary health care provider for almost 130,000 veterans in southeast Texas. Veterans from around the country are referred to the MEDVAMC for specialized diagnostic care, radiation therapy, surgery, and medical treatment including cardiovascular surgery, gastrointestinal endoscopy, nuclear medicine, ophthalmology, and treatment of spinal cord injury and diseases. The MEDVAMC is home to a Post-Traumatic Stress Disorder Clinic; Network Polytrauma Center; an award-winning Cardiac and General Surgery Program; Liver Transplant Center; VA Epilepsy and Cancer Centers of Excellence; VA Substance Abuse Disorder Quality Enhancement Research Initiative; Health Services Research & Development Center of Innovation; VA Rehabilitation Research of Excellence focusing on mild to moderate traumatic brain injury; Mental Illness Research, Education and Clinical Center; and one of the VA’s six Parkinson’s Disease Research, Education, and Clinical Centers. In late 2012, the MEDVAMC received official designation as a Kidney Transplant Center. Including the outpatient clinics in Beaumont, Conroe, Galveston, Houston, Katy, Lufkin, Richmond, Tomball and Texas City, MEDVAMC outpatient clinics log more than a million outpatient visits annually.

16225 Park Ten Place Suite 500 Houston, TX, 77084 United StatesMBP is a family-owned lab supply business that can help with consumables, reagents, custom oligos, and equipments. We also offer a revolutionary temperature/facility monitoring solution to help pharmaceutical companies maintain FDA and CDA 21 compliance.

MolecularMatch TMC X+ 2450 Holcombe Blvd Houston, TX, 77021 United StatesMolecularMatch is a clinical informatics company with expertise in precision oncology, immunotherapy and bioinformatics, combined with clinical insights empowering your solution. Leveraging technology licensed from the world’s #1 cancer center, M.D. Anderson, MolecularMatch has created unique proprietary treatment algorithms from world-leading physicians and scientists. Unlike other genomic service-oriented companies, MolecularMatch is a technology company first. Our proprietary technology delivers the deepest and broadest oncology genomic information in a biomedical ontology. We house a collaborative, self-learning tool with Natural Language Processing and machine learning capabilities. Specialties include: Clinical Trial Matching, Knowledge as a Service, Dynamic Reporting for Lab Reports, Somatic Assay Panel Development Support, Multi Variant Case Assessments, Physician Portals, EMR Integration for Decision Support, and Tumor Boards,

MolecularMatch TMC X+ 2450 Holcombe Blvd Houston, Texas, 77021 United StatesMolecularMatch is a clinical informatics company with expertise in precision oncology, immunotherapy and bioinformatics, combined with clinical insights empowering your solution. Leveraging technology licensed from the world’s #1 cancer center, M.D. Anderson, MolecularMatch has created unique proprietary treatment algorithms from world-leading physicians and scientists. Unlike other genomic service-oriented companies, MolecularMatch is a technology company first. Our proprietary technology delivers the deepest and broadest oncology genomic information in a biomedical ontology. We house a collaborative, self-learning tool with Natural Language Processing and machine learning capabilities. Specialties include: Clinical Trial Matching, Knowledge as a Service, Dynamic Reporting for Lab Reports, Somatic Assay Panel Development Support, Multi Variant Case Assessments, Physician Portals, EMR Integration for Decision Support, and Tumor Boards,

2450 Holcombe Blvd 1420 Houston, Texas, 77021 United StatesMS Pen Technologies, Inc. is commercializing the MasSpec Pen technology for rapid and direct chemical surface analysis.

2450 Holcombe Blvd 1420 Houston, TX, 77021 United StatesMS Pen Technologies, Inc. is commercializing the MasSpec Pen technology for rapid and direct chemical surface analysis.

7000 Fannin Street, Suite 2140 Houston, TX 77030 USANano3D Biosciences (n3D) specializes in developing systems for culturing cells in three-dimensions by magnetic levitation.

7000 Fannin St # 2140 Houston, TX, 77030 United StatesNano3D Biosciences (n3D) specializes in developing systems for culturing cells in three-dimensions by magnetic levitation.

555 Forge River Road, Suite 120 Webster, TX 77598NanoRacks is proudly democratizing the utilization of the low-earth orbit region of space. We are an entrepreneurial company that was the first to market its own hardware and services onboard the International Space Station. By providing a commercial pathway to using the Space Station, we have helped usher in a new chapter of the space frontier: making space just another place to do business. Our vision is to bring together three concepts as our driving force: low-cost, standardization of hardware, and understanding the customer. We like to believe that in space, small is the new big. Our customers include everyone from high schools to government space agencies, all who pay for our services on a commercial basis. The client base includes NASA, the German Space Agency, ESA, Planet Labs, Spire, biopharmaceutical firms, Urthecast and dozens of high schools and universities. We are thrilled that our customer base includes companies and organizations from Romania to Israel, from Peru to Saudi Arabia, as well as Vietnam, Japan, Canada and the UK, as well as a full range of government and private customers from the United States. Our services include Cubesat deployment, biopharm services, test platforms for advanced sensors for earth observation, research platforms for materials and educational research—wherever there is a need for space goods or services, NanoRacks seeks to be part of the commercial solution.

555 Forge River Road Webster, TX, 77598 United StatesNanoRacks is proudly democratizing the utilization of the low-earth orbit region of space. We are an entrepreneurial company that was the first to market its own hardware and services onboard the International Space Station. By providing a commercial pathway to using the Space Station, we have helped usher in a new chapter of the space frontier: making space just another place to do business. Our vision is to bring together three concepts as our driving force: low-cost, standardization of hardware, and understanding the customer. We like to believe that in space, small is the new big. Our customers include everyone from high schools to government space agencies, all who pay for our services on a commercial basis. The client base includes NASA, the German Space Agency, ESA, Planet Labs, Spire, biopharmaceutical firms, Urthecast and dozens of high schools and universities. We are thrilled that our customer base includes companies and organizations from Romania to Israel, from Peru to Saudi Arabia, as well as Vietnam, Japan, Canada and the UK, as well as a full range of government and private customers from the United States. Our services include Cubesat deployment, biopharm services, test platforms for advanced sensors for earth observation, research platforms for materials and educational research—wherever there is a need for space goods or services, NanoRacks seeks to be part of the commercial solution.

8285 El Rio St # 150, Houston, TX 77054Nanospectra Biosciences is a private company founded in 2002. Nanospectra has an exclusive license from Rice University to eleven issued US patents related to nanoshells and related commercial uses of these and other nanoparticles. While there are numerous therapeutic, diagnostic, and industrial commercial applications, Nanospectra is focused on the development of AuroLase® Therapy utilizing AuroShell® Particles (also referred to as nanoshells) for the precise, particle-based thermal ablation of solid tumors. Nanospectra commenced formal operations in 2002 to commercialize these applications. Nanospectra has an open Investigational Device Exemption (IDE) wtih the U.S. FDA to evaluate the safety and efficacy of AuroLase Therapy for the treatment of refractory or recurrent head and neck cancers. The use of AuroLase Therapy in other cancer types is under development. Nanoshells were developed in the laboratories of Naomi Halas, PhD, and Stanley C. Moore, Professor in Electrical and Computer Engineering and Professor of physics, chemistry, and Biomedical engineering at Rice University, in the 1990's. In collaboration with Jennifer West, PhD, and Isabel C. Cameron, Professor and Chair of Bioengineering of Rice University, a series of life science applications were envisioned which led to the formation of Nanospectra. Drs. Halas and West were named Inventors of the Year by the Texas Bar Assocation for one of their numerous patents licensed to Nanospectra.

2101 NASA Parkway Mail Code AT Houston, Texas 77058We actively promote partnerships between JSC’s researchers and industry, academia, and other government agencies.

5906 SYDNEY PARK LN SUGAR LAND, TX, 77479 United StatesIdentification and quantitation of peptide, protein, and glycoprotein biomarkers from various biologicals fluids : Plasma, Serum, Cell lysate, Saliva and Urine

7256 S. Sam Houston Pkwy W. Suite 300 Houston, TX, 77085 United StatesAccelerate Precision Oncology with a Trusted Biopharma Partner NeoGenomics empowers biopharma innovators to advance precision therapies from discovery through commercialization. Our integrated multi-modal testing, biomarker expertise, and real-world data insights help de-risk development, accelerate critical milestones, and bring transformative therapies to patients faster. Trusted by 300+ biopharma partners, including 85% of the top 20 • End-to-end multi-modal testing services through CAP-accredited and CLIA-certified laboratories in the United States and the United Kingdom. • Comprehensive, validated off-the-shelf assays and integrated data analysis. • Advanced customization for your program’s needs. • Experience across 25+ oncology indications, including solid, hematologic, and rare cancers. • Complimentary scientific consultation and strategic biomarker guidance. • Beyond lab data - de-risk your biomarker strategy with multi-modal real-world data and accelerate your timeline with qualified, timely patient insights and alerts. Core Capabilities Histopathology • Spatial Analysis • Genomics • Flow Cytometry • FISH & Cytogenetics • Multi-Modal Real-World Evidence

2575 West Bellfort St., Suite 2001 Houston, TX 77054Accelerate Precision Oncology with a Trusted Biopharma Partner NeoGenomics empowers biopharma innovators to advance precision therapies from discovery through commercialization. Our integrated multi-modal testing, biomarker expertise, and real-world data insights help de-risk development, accelerate critical milestones, and bring transformative therapies to patients faster. Trusted by 300+ biopharma partners, including 85% of the top 20 • End-to-end multi-modal testing services through CAP-accredited and CLIA-certified laboratories in the United States and the United Kingdom. • Comprehensive, validated off-the-shelf assays and integrated data analysis. • Advanced customization for your program’s needs. • Experience across 25+ oncology indications, including solid, hematologic, and rare cancers. • Complimentary scientific consultation and strategic biomarker guidance. • Beyond lab data - de-risk your biomarker strategy with multi-modal real-world data and accelerate your timeline with qualified, timely patient insights and alerts. Core Capabilities Histopathology • Spatial Analysis • Genomics • Flow Cytometry • FISH & Cytogenetics • Multi-Modal Real-World Evidence

13131 Dairy Ashford Road, Suite 225NETL provides carbon management, chemical reaction engineering, computational research, materials performance, and environmental science.

1775 N. Loop 336 W., Conroe, TX 77301Nova Biologicals provides services for water, medical device, pharmaceutical, nutraceutical, and food industries.

Conroe, TX United StatesNova Biologicals provides services for water, medical device, pharmaceutical, nutraceutical, and food industries.

800 Town And Country Blvd Ste 500 Houston, TX, 77024 4552 United StatesTalent Groups is a leading IT and Professional Staffing firm specializing in contract staffing, direct hire, executive search, and managed solutions. We unite the power of a national team of seasoned, client-facing personnel, localized delivery, and a global delivery center of experienced recruiters to help identify talent faster. Talent Group’s onshore delivery teams, combined with our recruiting center in Hyderabad, India, provides a vast, efficient, and streamlined recruiting service model that identifies highly qualified IT, Engineering, & Life Sciences professionals. At Talent Groups, our goal is to be your relationship-driven, one-stop partner for all your talent needs. We’ve carefully built out our teams, networks, and services to meet you exactly where you are in your journey. Whether you need one high impact hire to lead your organization, or a dozen proven professionals to step in and see a project through from start to finish; we are here for you and equipped to get the job done. We offer the geographic scale, industry expertise, and full-service client delivery model of a large staffing firm on a focused and personal basis to a broad range of clients. You need the best and brightest talent working for you to see your projects through from start to finish and hiring top talent can be a tall task on your own. No matter your location, the size of your organization, or your specific talent needs; we have the capabilities to help overcome that challenge. Building Tomorrow with Today’s Talent For more information, visit www.talentgroups.com.

800 Town and Country Blvd Ste 500 Houston, TX, 77024-4563 United StatesTalent Groups is a leading IT and Professional Staffing firm specializing in contract staffing, direct hire, executive search, and managed solutions. We unite the power of a national team of seasoned, client-facing personnel, localized delivery, and a global delivery center of experienced recruiters to help identify talent faster. Talent Group’s onshore delivery teams, combined with our recruiting center in Hyderabad, India, provides a vast, efficient, and streamlined recruiting service model that identifies highly qualified IT, Engineering, & Life Sciences professionals. At Talent Groups, our goal is to be your relationship-driven, one-stop partner for all your talent needs. We’ve carefully built out our teams, networks, and services to meet you exactly where you are in your journey. Whether you need one high impact hire to lead your organization, or a dozen proven professionals to step in and see a project through from start to finish; we are here for you and equipped to get the job done. We offer the geographic scale, industry expertise, and full-service client delivery model of a large staffing firm on a focused and personal basis to a broad range of clients. You need the best and brightest talent working for you to see your projects through from start to finish and hiring top talent can be a tall task on your own. No matter your location, the size of your organization, or your specific talent needs; we have the capabilities to help overcome that challenge. Building Tomorrow with Today’s Talent For more information, visit www.talentgroups.com.

9801 Bay Area Blvd. - Pasadena, , TX, 77507 United StatesGuided by innovation and sustainability, Oxiteno is a Brazilian chemical company that operates worldwide, leading manufacturer of surfactants and specialty chemicals. Present in nine countries in the Americas, Europe and Asia, Oxiteno has 12 industrial units located in Brazil, United States, Mexico, Uruguay and Venezuela and sales offices in Argentina, Belgium, Brazil, China, Colombia, United States, Mexico Uruguay and Venezuela. To believe in the future, envision business opportunities and develop solutions that contribute to people's quality of life and to the sustainable evolution of society and the world. This is the essence of our business which drives the development of technologies that meet the needs of our clients in different markets, such as Agrochemicals, Home Care and I&I, Oil & Gas, Paints & Coatings, Personal Care, among others. Business ethics and respect for people guide the way we operate and relate with all our stakeholders.

9801 Bay Area Blvd. - Pasadena, , TX , 77507 United StatesGuided by innovation and sustainability, Oxiteno is a Brazilian chemical company that operates worldwide, leading manufacturer of surfactants and specialty chemicals. Present in nine countries in the Americas, Europe and Asia, Oxiteno has 12 industrial units located in Brazil, United States, Mexico, Uruguay and Venezuela and sales offices in Argentina, Belgium, Brazil, China, Colombia, United States, Mexico Uruguay and Venezuela. To believe in the future, envision business opportunities and develop solutions that contribute to people's quality of life and to the sustainable evolution of society and the world. This is the essence of our business which drives the development of technologies that meet the needs of our clients in different markets, such as Agrochemicals, Home Care and I&I, Oil & Gas, Paints & Coatings, Personal Care, among others. Business ethics and respect for people guide the way we operate and relate with all our stakeholders.

9801 Bay Area Blvd. - Pasadena, TX 77507Guided by innovation and sustainability, Oxiteno is a Brazilian chemical company that operates worldwide, leading manufacturer of surfactants and specialty chemicals. Present in nine countries in the Americas, Europe and Asia, Oxiteno has 12 industrial units located in Brazil, United States, Mexico, Uruguay and Venezuela and sales offices in Argentina, Belgium, Brazil, China, Colombia, United States, Mexico Uruguay and Venezuela. To believe in the future, envision business opportunities and develop solutions that contribute to people's quality of life and to the sustainable evolution of society and the world. This is the essence of our business which drives the development of technologies that meet the needs of our clients in different markets, such as Agrochemicals, Home Care and I&I, Oil & Gas, Paints & Coatings, Personal Care, among others. Business ethics and respect for people guide the way we operate and relate with all our stakeholders.

1322 Space Park Dr. Suite B190 Houston, TX, 77058 United StatesPace® Life Sciences is an integrated CDMO, GMP laboratory, and pharma services partner supporting pharmaceutical, biopharmaceutical, medical device, and advanced therapy programs from development through commercialization. Our U.S. network combines scientific expertise, regulated laboratory infrastructure, clinical supply support, and operational services to help clients advance programs, maintain compliance, and support critical lab and manufacturing environments. Core capabilities include: -CMC development, preformulation, formulation, process development, and clinical trial materials support -GMP analytical testing, method development and validation, release testing, stability, microbiology, and product characterization -Support for small molecules, biologics, gene therapies, oligonucleotides, RNA, ADCs, combination products, medical devices, and complex drug products -Regulatory consulting, GxP consulting, quality systems support, and compliance readiness -Pharma services including technical field services, instrumentation support, facility qualification, lab relocation, cleanroom support, and scientific/regulatory staffing

9310 Kirby Drive Suite 900 Houston, Texas, 77054 United StatesPackGene is a world-leading CDMO company focus on providing end-to-end gene therapy solutions. Founded in 2014, PackGene now has offices in Houston (US) and Zurich (CH). PackGene provides economical, reliable, and scalable AAV viral vector, plasmid DNA, and mRNA production to support programs from early-stage drug discovery, preclinical development to IND enabling and clinical studies. Our proprietary π-Alpha™ 293 AAV High-yield Platform uses uniquely designed RC plasmid in the triple-plasmid transfection system to increase AAV production by 3 to 8 fold. PackGene's mission is to accelerate gene therapy product development by providing an integrated one-stop solution including plasmid, viral vector, fill-finish and QC analytical services for the gene therapy industry.

9310 Kirby Drive Suite 900 Houston, TX, 77054 United StatesPackGene is a world-leading CDMO company focus on providing end-to-end gene therapy solutions. Founded in 2014, PackGene now has offices in Houston (US) and Zurich (CH). PackGene provides economical, reliable, and scalable AAV viral vector, plasmid DNA, and mRNA production to support programs from early-stage drug discovery, preclinical development to IND enabling and clinical studies. Our proprietary π-Alpha™ 293 AAV High-yield Platform uses uniquely designed RC plasmid in the triple-plasmid transfection system to increase AAV production by 3 to 8 fold. PackGene's mission is to accelerate gene therapy product development by providing an integrated one-stop solution including plasmid, viral vector, fill-finish and QC analytical services for the gene therapy industry.

Unit 1104,, Level 11, Uptown 2At Parexel, speeding life-changing medicines to market begins by engaging patients With Heart™ With more than 24,000 life science professionals in 49 countries across six continents, Parexel’s people are the engine that drives clinical trial delivery, outcomes, and new medicines forward. We have made significant investment in our operations infrastructure to ensure consistent, predictable delivery all around the world as clinical research complexity continues to rise. Our trial execution framework integrates the latest innovations to efficiently manage increased research complexity, reach more patients while driving faster results for our customers and better outcomes for patients. And around the world, we’re investing today to develop a talent pool ready to deliver your next big breakthrough. The integration of clinical operations excellence and unparalleled regulatory consulting strength gives us an advantage when tackling the most complex trials in oncology, cell and gene therapies, rare diseases, and central nervous system disorders. We have a proven track record of strong performance in these areas, along with immunology, inflammation, and many more. We apply clinical operations and regulatory expertise to design clinical trials that help life-saving medicines reach patients sooner. From Phase I to Phase IV, global life sciences professionals work in partnership with biopharmaceutical sponsors to create trial experiences that are easier for patients to participate in and can serve as a viable care option for patients across a range of disease areas. Our depth of industry knowledge and strong track record gained over the past 40 years is moving the industry forward and advancing clinical research in healthcare’s most complex areas while our innovation ecosystem offers solutions throughout the product lifecycle – optimising data quality, creating better clinical trial experiences, and improving operational efficiencies – with the goal of driving better results for our customers and outcomes for patients. With the people, insight, and operational excellence to support a thriving R&D community, Parexel works With HeartTM to treat patients with dignity and learn from their experiences, so every trial makes a difference. In 2021, Parexel was acquired by EQT and Goldman Sachs Asset Management. We are headquartered in Raleigh, North Carolina, and employ 20,815 professionals in 49 countries. We are united by a core value that we believe influences every aspect of our work: We Care. We care about our people, our customers, our sites, and our partners.

Houston, TX United StatesPeptibody provides antibody and peptide synthesis services.

2750 Holly Hall St, Suite 1017Peptibody provides antibody and peptide synthesis services.

450 N. Sam Houston Parkway E.,Pharm-Olam International offers clinical research services such as project management, data management, regulatory, quality assurance, and pharmacovigilance.

3400 Research Forest DrivePower 3 offers products for early disease detection and disease research.

The Woodlands, TX United StatesPower 3 offers products for early disease detection and disease research.

P.O. Box 519 - Prairie View, , Texas , 77446 United StatesPrairie View A&M University is the second-oldest public institution of higher education in Texas. Offering baccalaureate degrees in 50 academic majors, 37 masters degrees and four doctoral degrees, this Historically Black University has an established reputation for producing thousands of African American engineers, nurses and educators. The University has been dedicated to fulfilling its land-grant mission of achieving excellence in teaching, research and service since 1876.

P.O. Box 519 - Prairie View, Texas 77446Prairie View A&M University is the second-oldest public institution of higher education in Texas. Offering baccalaureate degrees in 50 academic majors, 37 masters degrees and four doctoral degrees, this Historically Black University has an established reputation for producing thousands of African American engineers, nurses and educators. The University has been dedicated to fulfilling its land-grant mission of achieving excellence in teaching, research and service since 1876.

2575 West Bellfort Street Suite 190 Houston , TX, 77054 United StatesPrecision for Medicine is a global CRO with integrated specialty and central lab services, purpose-built for the complexities of modern drug development. Our model unites clinical trial execution, advanced laboratory capabilities, and data intelligence to accelerate breakthroughs from concept to commercialization. At the heart of this continuum are our ethically sourced, clinically annotated biospecimens—the critical entry point for discovery. With thousands of IRB-approved samples, Precision offers researchers access to a diverse and deeply characterized inventory of samples. Human Biological Samples: • Tissue: Over 3 million FFPE blocks and fresh or frozen tissues from healthy and diseased subjects, all pathologist-verified and ready for downstream applications like RNAseq, IHC, and molecular profiling. • Blood and Biofluids: Whole blood, plasma, serum, CSF, saliva, urine, and other biofluids collected from healthy and diseased subjects, including both clinically consented and remnant samples. • Viable Cells and Liquid Biopsy Kits: Including PBMCs, BMMCs, and dissociated tumor cells, with full kitting, logistics, and profiling services. • Matched Tissue and Blood Sets: Fresh, frozen, and FFPE tumor tissues paired with plasma, serum, or whole blood from the same subject, enabling integrated omics research, biomarker correlation, and immuno-oncology studies. • Custom Prospective Collections: Tailored to your research protocols, including rare disease cohorts, longitudinal samples, and fresh tissue for immune profiling, supported by Precision’s global clinical network. Lab Services Include: • Flow Cytometry & Cell-Based Assays: High-parameter flow cytometry, Immune cell profiling and functional assays, Rare cell detection and sorting • Genomics & Molecular Biology: qPCR, ddPCR, and NGS-based assays, Gene expression and mutation analysis, Epigenetic profiling • Proteomics & Biomarker Analysis: ELISA, multiplex immunoassays (Luminex, MSD), Western blotting and protein quantification, Custom biomarker development and validation • Immunology & Immuno-Oncology: Cytokine and chemokine profiling, T-cell activation and proliferation assays, Immunophenotyping and checkpoint analysis • Histology & Tissue-Based Services: FFPE tissue sectioning and staining, IHC/IF assay development and scoring, Digital pathology and image analysis • Bioanalytical & PK/PD Services: LC-MS/MS and ligand-binding assays, Pharmacokinetic and pharmacodynamic studies, Method development and validation under GLP/GCLP • Custom Assay Development: Fit-for-purpose assay design, Analytical validation and optimization, Regulatory support for clinical applications

6655 Travis St. Suite 840 Houston, TX, 77030 United StatesPRISM GENOMIC provides Next Generation Sequencing services to researchers at Texas Medical Center, in Houston and nationwide. We are committed to achieving a high level of customer satisfaction. We understand that your project is unique with its particular objectives and its own challenges. Regardless of size or complexity, each project will receive a personalized attention from us.

6655 Travis Street Houston, TX, 77030 United StatesPRISM GENOMIC provides Next Generation Sequencing services to researchers at Texas Medical Center, in Houston and nationwide. We are committed to achieving a high level of customer satisfaction. We understand that your project is unique with its particular objectives and its own challenges. Regardless of size or complexity, each project will receive a personalized attention from us.

3400 Bissonnet, Suite 130 Houston, TX 77005

Suite 200, 11700 Katy Fwy. Houston, TX 77079

9701 Richmond Avenue, Suite 222 Houston, Texas 77042Radiomedix,Inc. is a privately held biotechnology company founded in 2006 to develop and commercialize technology and products which will enable on-site and on-demand access to Positron Emission Tomography (“PET”). RadioMedix is developing its own chelation technology and new imaging conjugates, GlucoMedix and OncoMedix, which have the potential to significantly improve diagnosis and treatment monitoring for a variety of cancers. RadioMedix’s automated SmartMedixTM system, coupled with a small generator producing a PET isotope such as Gallium-68 (68Ga), will permit users to generate and label PET radiotracers on-site. It will significantly reduce cost of radiosynthesis that can be performed without the need for costly cyclotron facilities. RadioMedix is the exclusive distributor of all TRASIS and ITG radiopharmaceutical synthesizers in United States. RadioMedix also provides all the after sale service, installation and technical support for both TRASIS and ITG products in USA.

461 This Way StreetRD Clinical Research (RDCR) performs clinical research services.

PO Box 850 Montgomery , TX, 77365-0850 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

14408 W Sylvanfield Drive Houston, TX, 77014 United StatesScientist.com is the world’s largest marketplace for medical research. We help pharmaceutical scientists discover life-saving medicines in less time and at lower cost. Our mission is to make it possible to cure all human disease by 2050. By connecting scientists and enabling them to exchange ideas and transact seamlessly online, Scientist.com is speeding up and reducing the cost of medical research. We were founded in 2007, launched our first research outsourcing marketplace in 2008 and built our first enterprise marketplace for Pfizer in 2009. Today, we operate enterprise marketplaces for 24 of the world’s top 30 pharmaceutical companies, 100+ biotechnology companies and the US National Institutes of Health (NIH).

BioScience Research Collaborative (BRC) Rice University 6500 Main Street, MS-650 Houston, TX 77030-1402The BioScience Research Collaborative is an innovative space where scientists and educators from Rice University and other Texas Medical Center institutions work together to perform leading research that benefits human medicine and health. CindyFarachCarsonMore than just a building, it is an interdisciplinary, interinstitutional catalyst for new and better ways to collaborate, explore, learn and lead. As Scientific Director of the BRC and Vice Provost for Translational Bioscience, a primary focus for Dr. M. Cindy Farach-Carson is to build interdisciplinary research collaborations in the broad spectrum of biomedical and health research and education, and to assist faculty with establishing multidisciplinary translational research programs. Additional responsibilities include assisting with space planning, working closely with the Director of Operations and the Vice Provost for Research, to develop building programs that facilitate the scientific enterprise and bring vibrancy to the building’s activities.

6100 Main MS-550 Houston, TX, 77005 United States

9009 New Trails Drive The Woodlands, TX, 77381 United StatesRigaku offers services for electron diffraction crystallography exclusively. Rigaku is furthermore a market-leading manufacturer of instruments for electron diffraction crystallography and x-ray crystallography, x-ray diffraction, x-ray spectrometry, semiconductor metrology, automation, and cryogenics.

Rigaku Americas Corporation 9009 New Trails Drive The Woodlands, Texas, 77381 United StatesRigaku offers services for electron diffraction crystallography exclusively. Rigaku is furthermore a market-leading manufacturer of instruments for electron diffraction crystallography and x-ray crystallography, x-ray diffraction, x-ray spectrometry, semiconductor metrology, automation, and cryogenics.

Rigaku Americas Corporation 9009 New Trails Drive The Woodlands, TX, 77381 United StatesRigaku offers services for electron diffraction crystallography exclusively. Rigaku is furthermore a market-leading manufacturer of instruments for electron diffraction crystallography and x-ray crystallography, x-ray diffraction, x-ray spectrometry, semiconductor metrology, automation, and cryogenics.

9009 New Trails Drive The Woodlands The Woodlands TX 77381 USARigaku offers services for electron diffraction crystallography exclusively. Rigaku is furthermore a market-leading manufacturer of instruments for electron diffraction crystallography and x-ray crystallography, x-ray diffraction, x-ray spectrometry, semiconductor metrology, automation, and cryogenics.

155 Gibbs St, Suite 430Schrodinger provides visualization / simulation scientific software as well as Technology / Modeling services for Life sciences and Materials science customers globally.

2626 South Loop West, Suite 225 Houston, TX 77054 USASelleckBio, a Selleck Chemicals company, supplies high-performance life-science products. We have over 8,000 products which consist of inhibitors, antibodies, RNAis, proteins and peptides which focus on signaling pathways such as MAPK, PI3K/Akt, and apoptosis etc.

14408 W Sylvanfield Drive Houston, TX, 77014 United StatesSelleck Chemicals is one of the world's leading suppliers of biochemical products and services. We offer a diverse, well-curated and data-rich catalog of over 6000 small molecule inhibitors and modulators for multiple cell signaling pathways including MAPK, PI3K/Akt/mTOR, Apoptosis, Angiogenesis, and JAK/STAT, among others. In addition, we also provide a variety of screening libraries for High Throughput Screening and High Content Screening to advance drug discovery and systems biology research. All the inhibitors are well classified, so you can directly choose inhibitors according to signaling pathways or research areas listed in our company website. We boast a global operations network and overnight delivery on all in-stock items. Selleck Chemicals has established long-term and stable relationships with more than 10,000 customers from pharmaceutical and biotech companies to universities and research institutions. We have headquarters in the United States, Asia, Europe, and 38 distributors worldwide. We help the scientists of today deliver on the technologies of tomorrow. Put your research on the fast track with Selleck Chemicals. We look forward to supporting you!

2626 South Loop West, Suite 225, Houston, TX 77054 USASelleck Chemicals is one of the world's leading suppliers of biochemical products and services. We offer a diverse, well-curated and data-rich catalog of over 6000 small molecule inhibitors and modulators for multiple cell signaling pathways including MAPK, PI3K/Akt/mTOR, Apoptosis, Angiogenesis, and JAK/STAT, among others. In addition, we also provide a variety of screening libraries for High Throughput Screening and High Content Screening to advance drug discovery and systems biology research. All the inhibitors are well classified, so you can directly choose inhibitors according to signaling pathways or research areas listed in our company website. We boast a global operations network and overnight delivery on all in-stock items. Selleck Chemicals has established long-term and stable relationships with more than 10,000 customers from pharmaceutical and biotech companies to universities and research institutions. We have headquarters in the United States, Asia, Europe, and 38 distributors worldwide. We help the scientists of today deliver on the technologies of tomorrow. Put your research on the fast track with Selleck Chemicals. We look forward to supporting you!

900 Georgia Ave OGC Corporate Deer Park, TX, 77536 United StatesSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. As a global contract research organization, our global Health Science team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. In an ever-changing world, with technological change reaching breakneck speed, SGS helps navigate the sometimes complex process to successfully deliver high quality, safe and medical devices to market. SGS boasts a wealth of global health science expertise. We will support you every step of the way as you deliver first-class, fully compliant biopharmaceutical, pharmaceutical and medical device products. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs.

10410 Corporate Drive SUGAR LAND, TX, 77478 United StatesEstablished in 2021 in Texas, USA, GenoBioTX is committed to advancing life science research and drug discovery through cutting-edge model organisms, gene editing, and life-decoding technologies. As a subsidiary of Shanghai Model Organisms Center, we uphold the same high standards and credentials in delivering high-quality animal models and research services. Our Expertise: We specialize in developing genetically modified animal models, including: Humanized Mouse Models (e.g., immune checkpoint gene humanized models for antibody drug efficacy studies), Knockout, Knock-in, Transgenic, and Conditional Knockout Models Our Services: Customized Mouse Model Generation – Tailored genetic modifications to meet specific research needs CDX (Cell-Derived Xenograft) and PDX (Patient-Derived Xenograft) Mouse Models Phenotyping & Genotyping Services – Comprehensive analysis of genetic models PK/PD Study Services – Pharmacokinetics and pharmacodynamics research support Animal Breeding & Genotyping – Reliable colony management for long-term studies By leveraging our expertise, GenoBioTX aims to empower researchers with innovative tools for preclinical research and therapeutic development.

6420 Levit Green Blvd Ste 288 Houston, TX, 77021 United StatesSino Biological is a global leader in recombinant protein and antibody production and CRO services for life sciences research and drug development. Its facilities include the Center for Bioprocessing (C4B) in Houston, Texas, which specializes in mammalian cell-based protein and antibody production, and SignalChem Biotech (SCB) in Vancouver, Canada, focusing on kinase-related reagents, stable cell line development, and therapeutic discovery. With a U.S. office providing localized support, Sino Biological ensures innovative, high-quality solutions for global academic and industrial clients.

10101 Southwest Fwy Suite 100 Houston, TX, 77074 1126 United StatesSino Biological is a global leader in recombinant protein and antibody production and CRO services for life sciences research and drug development. Its facilities include the Center for Bioprocessing (C4B) in Houston, Texas, which specializes in mammalian cell-based protein and antibody production, and SignalChem Biotech (SCB) in Vancouver, Canada, focusing on kinase-related reagents, stable cell line development, and therapeutic discovery. With a U.S. office providing localized support, Sino Biological ensures innovative, high-quality solutions for global academic and industrial clients.

1770 Saint James Place, Suite 414 Houston, TX 77056 USASmart Imaging Technologies develops image analysis software and offers image analysis services.

Houston, TX United StatesSolvay Chemicals specializes in fluorine, peroxygen, and sodium based chemicals.

3333 Richmond Avenue Houston, TX 77098 USASolvay Chemicals specializes in fluorine, peroxygen, and sodium based chemicals.

1311 W Parkwood Ave Friendswood Texas 77546 USASongwon is the second largest manufacturer of polymer stabilizers in the world. Our vision is to be Salient in Additives and become the supplier of choice for polymer additives through our continued commitment to providing better quality, better service and better value to our customers. We are firmly focused on delivering growth by anticipating the needs and desires of our customers and by aspiring to be a leading example in additives technology development.

2450 Holcombe Blvd, Suite J Houston, Texas, 77021 United StatesSpanios is a Therapeutic Research Organization (TRO)/Contract Research Organization (CRO) that builds unique TME-rich Patient Derived Organoids (PDOs)/Tumoroids (PDT's) for rare and common cancers to be used for a variety of testing purposes including human efficacy testing. Spanios provides a range of services to its clients in academia, traditional biotech, and in-silico pharma to hasten the pace of their research by adding the human dimension to their data. Our COMPASS Platforms are both solid tumor indication and therapeutic modality agnostic. Ask us how Spanios can help with your research and drug validation. We have customized the work based on your specific research needs. Spanios is located by the Texas Medical Center & MD Anderson in Houston, TX, USA. Our current cancer organoid models include Breast, Gastric & Esophageal, Sarcoma, Cholangiocarcinoma, Pancreatic, Ovarian, Glioblastoma, Neuroendocrine, Bladder & Gallbladder cancers, and they can be generated for any solid tumor indication. They are fully characterized and stable and can be used to perform long-term longitudinal studies with complex dosing regimens and combination therapies.

2450 Holcombe Blvd, Suite J Houston, TX, 77021 United StatesSpanios is a Therapeutic Research Organization (TRO)/Contract Research Organization (CRO) that builds unique TME-rich Patient Derived Organoids (PDOs)/Tumoroids (PDT's) for rare and common cancers to be used for a variety of testing purposes including human efficacy testing. Spanios provides a range of services to its clients in academia, traditional biotech, and in-silico pharma to hasten the pace of their research by adding the human dimension to their data. Our COMPASS Platforms are both solid tumor indication and therapeutic modality agnostic. Ask us how Spanios can help with your research and drug validation. We have customized the work based on your specific research needs. Spanios is located by the Texas Medical Center & MD Anderson in Houston, TX, USA. Our current cancer organoid models include Breast, Gastric & Esophageal, Sarcoma, Cholangiocarcinoma, Pancreatic, Ovarian, Glioblastoma, Neuroendocrine, Bladder & Gallbladder cancers, and they can be generated for any solid tumor indication. They are fully characterized and stable and can be used to perform long-term longitudinal studies with complex dosing regimens and combination therapies.

15525 County Road 48 Rosharon, TX, 77583 United StatesSpecialty Glass, Inc. is dedicated to producing glassware that is consistent with regulatory requirements for glass apparatus used for testing in research and development labs according to scientific methods (ASTM). In addition to producing an excellent line of standard products, our skilled glassblowers take pride in their ability to develop prototypes for new lab glass designs and to repair damaged laboratory and scientific glassware efficiently and cost effectively.

One Baylor Plaza, N1210 MS BCM600 Houston, TX, 77030 United StatesStemMed provides state-of-the-art pre-clinical drug testing services using a large panel of patient-derived xenograft (PDX) models of breast and pancreatic cancers. Breast cancer PDX models were developed from an ethnically diverse patient population, and represent all clinically-defined subtypes, including estrogen receptor positive (ER+), HER2+, and “triple-negative” cancers.

7000 Fannin St., Suite 210 Houston, TX 77030StemMed provides state-of-the-art pre-clinical drug testing services using a large panel of patient-derived xenograft (PDX) models of breast and pancreatic cancers. Breast cancer PDX models were developed from an ethnically diverse patient population, and represent all clinically-defined subtypes, including estrogen receptor positive (ER+), HER2+, and “triple-negative” cancers.

12852 Park One Drive Sugar Land Texas 77478 USAStillmeadow offers toxicity studies, animal studies, batch analysis, preliminary analysis, and physical property determination.

12852 Park 1 Dr, Sugar Land, TX 77478STILLMEADOW, Inc. is an independent contract research facility focused on the professional evaluation of sponsors' products. Since 1975, we have expanded into a full service lab certified in the areas of mammalian and environmental toxicology, animal health, entomology, analytical services, and in vitro studies. STILLMEADOW, Inc. is AAALAC Accredited and certified with the National Environmental Laboratory Accreditation Program (NELAP.) We were certified by the Japanese Ministry of Agriculture, Forestry and Fisheries (MAFF) in 1992. In addition, key members of our staff are members of the Society of Quality Assurance, the Chemical Producers and Distributors Association, and the Society of Toxicology.

8044 El RioSynthecon specializes in the design and manufacture of 3D cell culture systems.

2450 Holcombe Blvd Suite 1640-A Houston, TX, 77021 2039 United StatesSystemic Bio's mission is to accelerate drug discovery and development with human-relevant data from bioprinted tissues. We provide services for drug-induced liver injury (DILI) and drug-induced vascular injury (DIVI) assessment of multi-modality therapeutics using our proprietary h-VIOS platform, which combines bioprinted vascularized tissues with microfluidics to enable complex healthy and diseased tissue modeling. We also work with partners to build custom complex tissue models of interest or generate human-relevant databases for in silico model training.

5000 Gulf Freeway Bld 5 Houston, TX, 77023 United States

7900 Fannin, #1030 Houston, TX 77054

Houston, TX United StatesTexas Children’s Cancer Center and Hematology Center offers cytogenetics, genomics, proteomics, and flow cytometry services.

6770 Bertner AvenueTexas Heart Institute focuses on cardiovascular research with emphasis on pathology, electrophysiology, stem cell, transplant, and heart assist devices.

2450 Holcombe Boulevard Houston, TX, 77021 United StatesThe Texas Medical Center (TMC)—the largest medical complex in the world—is at the forefront of advancing life sciences. As home to the brightest minds in medicine, TMC nurtures cross-institutional collaboration, creativity, and innovation. Because together, we can push the limits of what’s possible.

23501 Cinco Ranch Blvd. Suite H210 Katy, TX, 77494 United StatesToxStrategies is a multidisciplinary scientific consulting firm that strives to develop innovative solutions to address the scientific, technical, and regulatory challenges confronting our clients. We have a reputation for applying sound science in all that we do, for thinking outside-of-the-box, and for tailoring our approach to meet the specific needs of our clients, whether that need be for a rapid response or a comprehensive analysis. Our Epidemiology group focuses on pharmaceuticals, medical devices, and environmental chemicals. Our scientists aid clients in the conduct, evaluation, and interpretation of epidemiological studies. Our research frequently results in peer-reviewed publications and presentations at scientific conferences, as well as being used in numerous regulatory documents in the US and Europe.

23501 Cinco Ranch Blvd. Suite H210 Katy, Texas, 77494 United StatesToxStrategies is a multidisciplinary scientific consulting firm that strives to develop innovative solutions to address the scientific, technical, and regulatory challenges confronting our clients. We have a reputation for applying sound science in all that we do, for thinking outside-of-the-box, and for tailoring our approach to meet the specific needs of our clients, whether that need be for a rapid response or a comprehensive analysis. Our Epidemiology group focuses on pharmaceuticals, medical devices, and environmental chemicals. Our scientists aid clients in the conduct, evaluation, and interpretation of epidemiological studies. Our research frequently results in peer-reviewed publications and presentations at scientific conferences, as well as being used in numerous regulatory documents in the US and Europe.

23501 Cinco Ranch Boulevard Suite B226 Katy, TX, 77494 United StatesToxStrategies is a multidisciplinary scientific consulting firm that strives to develop innovative solutions to address the scientific, technical, and regulatory challenges confronting our clients. We have a reputation for applying sound science in all that we do, for thinking outside-of-the-box, and for tailoring our approach to meet the specific needs of our clients, whether that need be for a rapid response or a comprehensive analysis. Our Epidemiology group focuses on pharmaceuticals, medical devices, and environmental chemicals. Our scientists aid clients in the conduct, evaluation, and interpretation of epidemiological studies. Our research frequently results in peer-reviewed publications and presentations at scientific conferences, as well as being used in numerous regulatory documents in the US and Europe.

1122 Forest Knoll LaneTriumpharma offers clinical research, stability testing, bioanalytical testing, in situ/in vivo/in vitro permeability studies, and toxicity services.

5829 W. Sam Houston Pkwy N. Suite 1105 Houston, TX 77041Turf Feeding Systems is a leader in packaged fertigation systems for irrigated landscapes, sports fields, golf courses, resorts and agriculture sites across the US and around the world. We have over 28 years of experience building the best fertigation systems with the highest quality and longest service life at the best price. We offer more than the best fertigation systems. We can help any customer achieve high quality landscapes or crops, while reducing water and costs. We can implement Sustainability and Water Efficiency into any irrigated area to reduce water use up to 50%, reduce fertilizer and chemical use 60%, while improving the overall quality or crop production. We are sharply focused on Sustainability, Water Efficiency and Soil Health. Our fertigation systems are the tools needed to achieve these benefits. Our systems are installed on thousands of sites, including some of the top golf courses in the world, 5-star resorts, municipal parks, sports fields and agriculture areas across the US, Asia, Pacific Rim, Europe, Middle East, Africa and South America. Let us help you implement Sustainability and Water Efficiency into your property or project.

Dept of Neurobiology and Anatomy | The University of Texas Medical School at Houston | 6431 Fannin St - Suite MSB 7.046 | Houston, TX 77030 USA

1825 Pressler Street Houston, TX, 77030 United States

1825 Pressler Street Houston, TX, 77030 United States

1825 Pressler Street Houston, TX, 77030 United States

Houston, TX United StatesUniversity of Texas M.D. Anderson Cancer Center offers epigenetics, genomics, proteomics, sequencing, and image analysis services.

1515 Holcombe BlvdUniversity of Texas M.D. Anderson Cancer Center offers epigenetics, genomics, proteomics, sequencing, and image analysis services.

4800 Calhoun RoadUniversity of Houston Health and Human Performance focuses on research.

The Woodlands, TX United StatesUS Oncology, acquired by McKesson, focuses on clinical research in the field of oncology.

10101 Woodloch ForestUS Oncology, acquired by McKesson, focuses on clinical research in the field of oncology.

3302 Twing Leaf Lane Houston, TX, 77084 United States

Houston, TX USATo enhance the understanding of oncogenic pathways and drive the development of new cancer therapies through provision of protein production, biophysical characterization, and structural biology resources. How can the core for biomolecular structure and function impact your work? We can provide you with pure protein that is ready for assay development in your laboratory or biophysical assays within ours. We have state of the art biophysical instrumentation to answer questions such as: What is the oligomerization state of my protein? What is the affinity of a small molecule for my protein How does phosphorylation of my target protein affect protein-complex formation? Does my protein form a complex with another protein as suggested by Co-IP? What is the 3-dimensional structure of my protein? These are just example questions that can be thoroughly investigated in our group. Please do not hesitate to contact us and see if we can assist you with your specific question.

Houston, TX, 77030 United StatesTo enhance the understanding of oncogenic pathways and drive the development of new cancer therapies through provision of protein production, biophysical characterization, and structural biology resources. How can the core for biomolecular structure and function impact your work? We can provide you with pure protein that is ready for assay development in your laboratory or biophysical assays within ours. We have state of the art biophysical instrumentation to answer questions such as: What is the oligomerization state of my protein? What is the affinity of a small molecule for my protein How does phosphorylation of my target protein affect protein-complex formation? Does my protein form a complex with another protein as suggested by Co-IP? What is the 3-dimensional structure of my protein? These are just example questions that can be thoroughly investigated in our group. Please do not hesitate to contact us and see if we can assist you with your specific question.

1155 Pressler St. Houston, TX 77030-3721 The Bionutrition Research Core was established in 2015 as a strategic initiative of the Duncan Family Institute for Cancer Prevention and Risk Assessment, which is housed in the Division of Cancer Prevention and Population Sciences. The mission of the Bionutrition Research Core is to assist investigators who examine the role of diet in cancer prevention and progression to conduct state-of-the-art nutritional science research by establishing best dietary practices and by providing the resources necessary to plan and conduct human feeding studies. With guidance from MD Anderson’s Clinical Nutrition department and our multi-disciplinary steering committee, we provide services to examine both the direct and indirect links between diet and cancer risk and disease along the cancer continuum in clinical, community and survivorship populations.

1155 Pressler St. Houston, , TX , 77030-3721 United States The Bionutrition Research Core was established in 2015 as a strategic initiative of the Duncan Family Institute for Cancer Prevention and Risk Assessment, which is housed in the Division of Cancer Prevention and Population Sciences. The mission of the Bionutrition Research Core is to assist investigators who examine the role of diet in cancer prevention and progression to conduct state-of-the-art nutritional science research by establishing best dietary practices and by providing the resources necessary to plan and conduct human feeding studies. With guidance from MD Anderson’s Clinical Nutrition department and our multi-disciplinary steering committee, we provide services to examine both the direct and indirect links between diet and cancer risk and disease along the cancer continuum in clinical, community and survivorship populations.

1155 Pressler St. Houston, , TX, 77030-3721 United States The Bionutrition Research Core was established in 2015 as a strategic initiative of the Duncan Family Institute for Cancer Prevention and Risk Assessment, which is housed in the Division of Cancer Prevention and Population Sciences. The mission of the Bionutrition Research Core is to assist investigators who examine the role of diet in cancer prevention and progression to conduct state-of-the-art nutritional science research by establishing best dietary practices and by providing the resources necessary to plan and conduct human feeding studies. With guidance from MD Anderson’s Clinical Nutrition department and our multi-disciplinary steering committee, we provide services to examine both the direct and indirect links between diet and cancer risk and disease along the cancer continuum in clinical, community and survivorship populations.

1515 Holcombe Boulevard Houston, TX, 77030 United StatesThe Biospecimen Extraction Resource (BER) provides a centralized laboratory for standardized, high-quality DNA, RNA and protein extraction from blood, tissues, saliva, cells, or other patient-derived biospecimens. Additional services include DNA gel electrophoresis, Picogreen DNA quantitation, real-time PCR DNA quantitation, and whole blood processing for lymphocytes and plasma. Our facility is utilized by both lab-based investigators who want fast turn-around time for standardized and high-quality extractions or whole blood processing and non-lab-based investigators (majority are clinicians) who are in great need of the service of sample processing. High quality of DNA/RNA products is the foundation of successful cancer research such as analysis of genetic alterations, gene expression profiling and next generation sequencing. We work very closely with the Sequencing and Microarray Facility (SMF) and the DNA/RNA samples extracted from us can be submitted directly from our core to SMF across the hallway.

Houston, TX USAThe Bone Histomorphometry Core Laboratory provides histomorphometric analyses of non-decalcified bone specimens, including processing mouse bone specimens for non-decalcified histology and performing static and dynamic histomorphometric analyses of mouse bone specimens. The service is performed on a subsidized fee-for-service basis. The function of the Bone Histomorphometry core is to perform histomorphometric analyses of non-decalcified bone specimens. Processing mouse bone specimen for non-decalcified histology. Fixed and partially dehydrated mouse skeleton is provided by project investigators to the Core. These samples are embedded in plastic medium, sectioned and stained. Contact Michael Starbuck, mwstarbu@mdanderson.org, for more information on the protocol for proper sample preparation. Performing static and dynamic histomorphometric analyses of mouse bone specimen. Using the Osteomeasure analytic system and the Bioquant Osteo II system, static parameters such as bone volume, trabecular number and cell counts as well as dynamic parameters of bone formation such as mineral apposition rates are quantified on non-decalcified bone sections. The core provides investigators with the data and will help them in evaluating their biological relevance. About Bone Histomorphometry Core Laboratory Purpose To provide the faculty affiliated with the Bone Disease Program of Texas with high quality bone histomorphometry processing; analysis of the skeleton of genetically modified mice and tumor-bearing bones, and micro-CT analysis of bone specimens.

Houston, TX, 77030 United StatesThe Bone Histomorphometry Core Laboratory provides histomorphometric analyses of non-decalcified bone specimens, including processing mouse bone specimens for non-decalcified histology and performing static and dynamic histomorphometric analyses of mouse bone specimens. The service is performed on a subsidized fee-for-service basis. The function of the Bone Histomorphometry core is to perform histomorphometric analyses of non-decalcified bone specimens. Processing mouse bone specimen for non-decalcified histology. Fixed and partially dehydrated mouse skeleton is provided by project investigators to the Core. These samples are embedded in plastic medium, sectioned and stained. Contact Michael Starbuck, mwstarbu@mdanderson.org, for more information on the protocol for proper sample preparation. Performing static and dynamic histomorphometric analyses of mouse bone specimen. Using the Osteomeasure analytic system and the Bioquant Osteo II system, static parameters such as bone volume, trabecular number and cell counts as well as dynamic parameters of bone formation such as mineral apposition rates are quantified on non-decalcified bone sections. The core provides investigators with the data and will help them in evaluating their biological relevance. About Bone Histomorphometry Core Laboratory Purpose To provide the faculty affiliated with the Bone Disease Program of Texas with high quality bone histomorphometry processing; analysis of the skeleton of genetically modified mice and tumor-bearing bones, and micro-CT analysis of bone specimens.

Translational Molecular Pathology LSP9.4127 2130 W Holcombe Blvd HT 77030

6565 MD Anderson Blvd. Room Z4.2040 Houston, , TX , 77030 United StatesBetween 18% and 36% of cell lines are either misidentified or cross-contaminated (list of misidentified cell lines). A recent notice from NIH requires cell line validation for grant applications to be considered of the highest quality. Journals such as Science, Nature and PNAS also require cell line validation for publication. Cell lines that have been extensively characterized at the DNA, RNA and protein levels will allow investigators to choose the correct cell line for their research. Pre-characterized cell lines will decrease the cost to researchers since this will eliminate repeat analysis. Thus, cell line validation is a critical issue for both scientific publications and grant applications.

6565 MD Anderson Blvd. Room Z4.2040 Houston, , TX, 77030 United StatesBetween 18% and 36% of cell lines are either misidentified or cross-contaminated (list of misidentified cell lines). A recent notice from NIH requires cell line validation for grant applications to be considered of the highest quality. Journals such as Science, Nature and PNAS also require cell line validation for publication. Cell lines that have been extensively characterized at the DNA, RNA and protein levels will allow investigators to choose the correct cell line for their research. Pre-characterized cell lines will decrease the cost to researchers since this will eliminate repeat analysis. Thus, cell line validation is a critical issue for both scientific publications and grant applications.

6565 MD Anderson Blvd. Room Z4.2040 Houston, TX 77030Between 18% and 36% of cell lines are either misidentified or cross-contaminated (list of misidentified cell lines). A recent notice from NIH requires cell line validation for grant applications to be considered of the highest quality. Journals such as Science, Nature and PNAS also require cell line validation for publication. Cell lines that have been extensively characterized at the DNA, RNA and protein levels will allow investigators to choose the correct cell line for their research. Pre-characterized cell lines will decrease the cost to researchers since this will eliminate repeat analysis. Thus, cell line validation is a critical issue for both scientific publications and grant applications.

Clinical Research Building Houston, TX, 77030 United StatesThe DNA Methylation Analysis Facility is funded by the Center for Cancer Epigenetics and provides services related to the analysis of DNA methylation for researchers across all MD Anderson campuses and in the Texas Medical Center. Services include: consultation with investigators to chose the best method of analysis; sample preparation, assay design and processing of the most used methods to study DNA methylation, both gene-specific and genome-wide (PyroMeth, RRBS and Methyl-Seq); developing and maintaining a library of commonly used assays to measure global DNA methylation (LINE, Alu) and common gene-specific tests (p16, e-cadherin, MLH1, p15 and others). The core is located at the Clinical Research Building of the MD Anderson Cancer Center in Houston. We are fully equipped for molecular biology research and have a Qiagen Pyrosequencing machine.

Houston, TX USAThe DNA Methylation Analysis Facility is funded by the Center for Cancer Epigenetics and provides services related to the analysis of DNA methylation for researchers across all MD Anderson campuses and in the Texas Medical Center. Services include: consultation with investigators to chose the best method of analysis; sample preparation, assay design and processing of the most used methods to study DNA methylation, both gene-specific and genome-wide (PyroMeth, RRBS and Methyl-Seq); developing and maintaining a library of commonly used assays to measure global DNA methylation (LINE, Alu) and common gene-specific tests (p16, e-cadherin, MLH1, p15 and others). The core is located at the Clinical Research Building of the MD Anderson Cancer Center in Houston. We are fully equipped for molecular biology research and have a Qiagen Pyrosequencing machine.

Houston TX 77030 USAThe Flow Cytometry and Cellular Imaging (FCCI) Core Facility was established in 1982 with the goal of providing the large community of investigators at MD Anderson with access to state-of-the-art cell analysis technology. The Core has expanded the number of technologies offered and in use by cancer center members. The FCCI Core includes two separate labs at the north and south campus. Institutional needs for flow cytometry services were carefully evaluated in 2008 and a decision was made to transition the operation of the South Campus Flow Cytometry and Cell Sorting Facility to a CCSG core to provide the sufficient capacity to support the institution's investigators. Both the North and South Campus facilities are open to the entire MD Anderson research community.

Houston, TX, 77030 United StatesThe purpose of the Genetically Engineered Mouse Facility (GEMF) is to provide technologically advanced and efficient mouse mutation resources to faculty members at the institution. Modifications to the genome utilizing direct DNA injection and ES cell mutagenesis, cryopreservation, in vitro fertilization and rederivation of mouse lines are all technologies supported by the facility. The facility is fully equipped with the latest instrumentation and staffed with highly skilled personnel trained specifically for the production of mutant mice.

Houston, TX USA 77030The purpose of the Genetically Engineered Mouse Facility (GEMF) is to provide technologically advanced and efficient mouse mutation resources to faculty members at the institution. Modifications to the genome utilizing direct DNA injection and ES cell mutagenesis, cryopreservation, in vitro fertilization and rederivation of mouse lines are all technologies supported by the facility. The facility is fully equipped with the latest instrumentation and staffed with highly skilled personnel trained specifically for the production of mutant mice.

1515 Holcombe Boulevard Houston, TX, 77030 United StatesThe purpose of the Gynecologic Cancer Translational Research Tissue Bank is to provide investigators with primary human tissue for research projects relating to gynecologic cancer. Priority for samples is given to the MD Anderson scientific community.

1515 Holcombe Blvd., Unit 173, Houston, , TX,, 77030 United StatesThe High Resolution Electron Microscopy Facility (HREMF) provides a resource to the scientific community at MD Anderson for high resolution imaging of cells, tissues, organs or polymers containing cancer agents. The facility is located at the Smith Research Building (South Campus) and houses a JEOL JEM-1010 transmission electron microscope (TEM), a JEOL JSM-5900 scanning electron microscope (SEM) equipped with a backscattered electron detector, a Bal-Tec Technotrade coating system, a Leica Ultramicrotome, Leica Ultrostainer and other ancillary accessories needed to prepare samples for SEM and TEM. A technologist with histological training is available to assist researchers in defining their specific needs related to SEM and TEM. Both electron microscopes are equipped with digital cameras. The facility operates on a charge-back basis only for processing of samples and the number of microscope hours used to examine samples with technical assistance.

1515 Holcombe Blvd., Unit 173, Houston, TX, 77030The High Resolution Electron Microscopy Facility (HREMF) provides a resource to the scientific community at MD Anderson for high resolution imaging of cells, tissues, organs or polymers containing cancer agents. The facility is located at the Smith Research Building (South Campus) and houses a JEOL JEM-1010 transmission electron microscope (TEM), a JEOL JSM-5900 scanning electron microscope (SEM) equipped with a backscattered electron detector, a Bal-Tec Technotrade coating system, a Leica Ultramicrotome, Leica Ultrostainer and other ancillary accessories needed to prepare samples for SEM and TEM. A technologist with histological training is available to assist researchers in defining their specific needs related to SEM and TEM. Both electron microscopes are equipped with digital cameras. The facility operates on a charge-back basis only for processing of samples and the number of microscope hours used to examine samples with technical assistance.

7455 Fannin St., Unit 902, Houston, , TX, , 77030 United StatesWe specialize in advanced fluorescence microscopy modes such as super-resolution, confocal and dynamic microscopy and provide the instrument access, training, expertise and collaboration to researchers in MD Anderson's Center for Cancer Immunology Research (CCIR), as well as to external users.

MD Anderson South Campus Research Building 1 Room 4.3123 7455 Fannin Street Houston, TX 77054We specialize in advanced fluorescence microscopy modes such as super-resolution, confocal and dynamic microscopy and provide the instrument access, training, expertise and collaboration to researchers in MD Anderson's Center for Cancer Immunology Research (CCIR), as well as to external users.

Houston, TX, 77030 United StatesThe T. C. Hsu Molecular Cytogenetics Facility (MCF) is funded by the Center for Genetics and Genomics (CGG). Guillermina Lozano, Ph.D. is the Director and Asha S. Multani, Ph.D. is the Co-Director of the facility. The MCF is administered through theDepartment of Genetics. This facility offers Conventional as well as Molecular Cytogenetic services including cell line authentication, species identification, karyotyping, analysis of genomic instability, fluorescence in situ hybridization and Spectral Karyotyping. One of the key expertise of our facility is to validate the origin of cell lines. Approximately 20-30% of all cell lines used in biomedical research are contaminated. Many top tier journals have begun to request proof of cell line authentication from investigators. Unlike other methods, chromosomal analysis is able to unambiguously identify cells from all common mammalian species and can also differentiate between cells from the same species. This analysis can therefore identify intra-species and inter-species cell line contaminations.

Houston TX 77030 USAThe T. C. Hsu Molecular Cytogenetics Facility (MCF) is funded by the Center for Genetics and Genomics (CGG). Guillermina Lozano, Ph.D. is the Director and Asha S. Multani, Ph.D. is the Co-Director of the facility. The MCF is administered through theDepartment of Genetics. This facility offers Conventional as well as Molecular Cytogenetic services including cell line authentication, species identification, karyotyping, analysis of genomic instability, fluorescence in situ hybridization and Spectral Karyotyping. One of the key expertise of our facility is to validate the origin of cell lines. Approximately 20-30% of all cell lines used in biomedical research are contaminated. Many top tier journals have begun to request proof of cell line authentication from investigators. Unlike other methods, chromosomal analysis is able to unambiguously identify cells from all common mammalian species and can also differentiate between cells from the same species. This analysis can therefore identify intra-species and inter-species cell line contaminations.

6565 MD Anderson Blvd. Room Z3.4023 Houston, Texas 77030The Molecular Diagnostics Laboratory is a CLIA-certified clinical diagnostic facility specializing in oncologic molecular testing. We provide a full roster of testing for leukemia, lymphoma and a variety of other malignancies. Our laboratory can analyze samples from patients at MD Anderson Cancer Center as well as serve as a referral laboratory for other hospitals and clinics.

6565 MD Anderson Blvd. Room Z3.4023 Houston, , Texas , 77030 United StatesThe Molecular Diagnostics Laboratory is a CLIA-certified clinical diagnostic facility specializing in oncologic molecular testing. We provide a full roster of testing for leukemia, lymphoma and a variety of other malignancies. Our laboratory can analyze samples from patients at MD Anderson Cancer Center as well as serve as a referral laboratory for other hospitals and clinics.

South Campus Research Building I (SCRB I) 7455 Fannin Street, Unit 902 Houston, , TX, 77054 United StatesThe Monoclonal Antibody Facility (MABF) provides custom monoclonal antibody production and purification to researchers at MD Anderson and beyond. The main focus of the facility is to produce high-affinity antibodies in a high-throughput and effective manner, while concentrating on quality of product and service, as well as saving time and money for potential users.

South Campus Research Building I (SCRB I) 7455 Fannin Street, Unit 902 Houston, , TX , 77054 United StatesThe Monoclonal Antibody Facility (MABF) provides custom monoclonal antibody production and purification to researchers at MD Anderson and beyond. The main focus of the facility is to produce high-affinity antibodies in a high-throughput and effective manner, while concentrating on quality of product and service, as well as saving time and money for potential users.

South Campus Research Building I (SCRB I) 7455 Fannin Street, Unit 902 Houston, TX 77054The Monoclonal Antibody Facility (MABF) provides custom monoclonal antibody production and purification to researchers at MD Anderson and beyond. The main focus of the facility is to produce high-affinity antibodies in a high-throughput and effective manner, while concentrating on quality of product and service, as well as saving time and money for potential users.

1901 East Road, Room 4SCR1.1335. Houston, , TX, , 77054 United StatesThe NMR facility houses two state-of-the-art spectrometers for use in the determination of the structure of small molecules and biological macromolecules, reaction kinetics, macromolecule dynamics, metabolism, etc. Samples are analyzed either by individual users or by Kumaralal K. Kaluarachchi, Ph.D., the facility manager.

1901 East Road, Houston, TX, 77054, Room 4SCR1.1335.The NMR facility houses two state-of-the-art spectrometers for use in the determination of the structure of small molecules and biological macromolecules, reaction kinetics, macromolecule dynamics, metabolism, etc. Samples are analyzed either by individual users or by Kumaralal K. Kaluarachchi, Ph.D., the facility manager.

Houston , TX, 77030 United StatesThe Nucleic Acid Core Facility provides the following services: Genomic DNA extraction from mouse tails and tissues and PCR-based genetic testing DNA extraction from peripheral blood leukocytes MSI testing PCR and fragment analysis of DNA RNA, DNA and protein extraction DNA and RNA extraction from solid tissues cDNA PCR for submission to DNA sequencing core

Houston TX 77030 USAThe Nucleic Acid Core Facility provides the following services: Genomic DNA extraction from mouse tails and tissues and PCR-based genetic testing DNA extraction from peripheral blood leukocytes MSI testing PCR and fragment analysis of DNA RNA, DNA and protein extraction DNA and RNA extraction from solid tissues cDNA PCR for submission to DNA sequencing core

Department of Hematopathology, Unit 072 Attn: Outside Services, room R4.2317A 1515 Holcombe Blvd. Houston, , Texas , 77030-4009 United StatesDiagnostic Testing For diagnostic consultations only, please complete the Hematopathology Consultation Request Form (pdf). Both glass slides and a representative paraffin block are encouraged. (Consultation requests consisting of slides and blocks only should be sent to R4.2317A.) Laboratory Testing For laboratory testing of samples, please complete Hematopathology Outside Services Test Requisition (pdf). Send the Outside Services Test Requisition along with the samples to the appropriate lab; the address is indicated on the instruction form attached to the requisition.

Department of Hematopathology, Unit 072 Attn: Outside Services, room R4.2317A 1515 Holcombe Blvd. Houston, Texas 77030-4009Diagnostic Testing For diagnostic consultations only, please complete the Hematopathology Consultation Request Form (pdf). Both glass slides and a representative paraffin block are encouraged. (Consultation requests consisting of slides and blocks only should be sent to R4.2317A.) Laboratory Testing For laboratory testing of samples, please complete Hematopathology Outside Services Test Requisition (pdf). Send the Outside Services Test Requisition along with the samples to the appropriate lab; the address is indicated on the instruction form attached to the requisition.

1515 Holcombe Blvd., Unit 1330, Houston, , TX, , 77030 United StatesThe Patient-Reported Outcomes, Survey & Population Research (PROSPR) Shared Resource provides researchers with access to state-of-the-art patient-reported outcome (PRO), quality of life, psychological and behavioral questionnaires and assessment methods. Our services include assisting investigators in identifying existing measures, developing new measures and designing data collection strategies and conducting psychometric analysis. The PROSPR Shared Resource will also develop databases for the questionnaire data entry, participant tracking databases and computer- and web-based assessments. We also provide fitness and body composition assessments including VO2 max testing, accelerometers to measure activity, including the ability to lease accelerometers for a study, anthropometric measurements, physical functioning tests, strength assessments using the Biodex system, DXA scans, and venous blood draws. The PROSPR Shared Resource maintains a library of existing questionnaires, along with information pertaining to their reliability, validity and scoring. The PROSPR Shared Resource also provides assessment services related to energy balance research, focusing on both body composition and assessment of physical fitness and exercise behavior.

1515 Holcombe Blvd., Unit 1330, Houston, TX, 77030.The Patient-Reported Outcomes, Survey & Population Research (PROSPR) Shared Resource provides researchers with access to state-of-the-art patient-reported outcome (PRO), quality of life, psychological and behavioral questionnaires and assessment methods. Our services include assisting investigators in identifying existing measures, developing new measures and designing data collection strategies and conducting psychometric analysis. The PROSPR Shared Resource will also develop databases for the questionnaire data entry, participant tracking databases and computer- and web-based assessments. We also provide fitness and body composition assessments including VO2 max testing, accelerometers to measure activity, including the ability to lease accelerometers for a study, anthropometric measurements, physical functioning tests, strength assessments using the Biodex system, DXA scans, and venous blood draws. The PROSPR Shared Resource maintains a library of existing questionnaires, along with information pertaining to their reliability, validity and scoring. The PROSPR Shared Resource also provides assessment services related to energy balance research, focusing on both body composition and assessment of physical fitness and exercise behavior.

Houston, TX, 77030 United StatesThe Pharmaceutical Science Facility provides MD Anderson investigators and Texas Medical Center researchers access to state-of-the-art bioanalytical support to advance their clinical and preclinical projects. We focus on quantification of small molecules in biologic and non-biologic matrices (i.e., plasma, serum, whole blood, tissues, cell culture media, buffer solutions, aqueous and organic solutions or extracts). For analysis of proteins and very large molecules, please refer to the Proteomics Core Facility.

Houston, TX 77030 USAThe Pharmaceutical Science Facility provides MD Anderson investigators and Texas Medical Center researchers access to state-of-the-art bioanalytical support to advance their clinical and preclinical projects. We focus on quantification of small molecules in biologic and non-biologic matrices (i.e., plasma, serum, whole blood, tissues, cell culture media, buffer solutions, aqueous and organic solutions or extracts). For analysis of proteins and very large molecules, please refer to the Proteomics Core Facility.

Department of Systems Biology, Unit 950 Room 2SCR3.3123 7435 Fannin St. Houston, TX 77054The Proteomics and Metabolomics Facility provides state-of-the-art mass spectrometry analysis of proteins and metabolites for both basic and clinical cancer research. We strive to serve all internal and external investigators by providing access to mass-spectrometry based proteomics and metabolomics technologies and services.

Department of Systems Biology, Unit 950 Room 2SCR3.3123 7435 Fannin St. Houston, TX, 77054 United StatesThe Proteomics and Metabolomics Facility provides state-of-the-art mass spectrometry analysis of proteins and metabolites for both basic and clinical cancer research. We strive to serve all internal and external investigators by providing access to mass-spectrometry based proteomics and metabolomics technologies and services.

8060 El Rio St., ERD 1.200 Houston, , TX, 77054-4186 United StatesMailed Thermoluminescent Dosimeters (TLD) for Quality Assurance Radiation Therapy Machine Output Checks The MD Anderson Radiation Dosimetry Services (RDS) provides independent peer reviews of beam output for radiation dose delivery systems. Specifically, we provide output checks for external beam radiation therapy machines including: megavoltage photon (2 - 25 MV) electron (4 - 20 MeV) orthovoltage (1.9 mm Al - 3 mm Cu HVL) Cobalt-60 Absorbed Dose in Blood Irradiators Thermoluminescent dosimeters (TLD) are available by mail to check the absorbed dose to the blood in irradiators used by blood banks. Packets of dosimeters are supplied; these can be placed at various locations to monitor the range of dose throughout the canister for a typical irradiation. These measurements are an independent check of the calibration of the blood irradiator as provided by the manufacturer. Radiation Dosimetry Services also offers checks of: total body dosimetry total skin dosimetry

8060 El Rio St., ERD 1.200 Houston, , TX , 77054-4186 United StatesMailed Thermoluminescent Dosimeters (TLD) for Quality Assurance Radiation Therapy Machine Output Checks The MD Anderson Radiation Dosimetry Services (RDS) provides independent peer reviews of beam output for radiation dose delivery systems. Specifically, we provide output checks for external beam radiation therapy machines including: megavoltage photon (2 - 25 MV) electron (4 - 20 MeV) orthovoltage (1.9 mm Al - 3 mm Cu HVL) Cobalt-60 Absorbed Dose in Blood Irradiators Thermoluminescent dosimeters (TLD) are available by mail to check the absorbed dose to the blood in irradiators used by blood banks. Packets of dosimeters are supplied; these can be placed at various locations to monitor the range of dose throughout the canister for a typical irradiation. These measurements are an independent check of the calibration of the blood irradiator as provided by the manufacturer. Radiation Dosimetry Services also offers checks of: total body dosimetry total skin dosimetry

8060 El Rio St., ERD 1.200 Houston, TX 77054-4186Mailed Thermoluminescent Dosimeters (TLD) for Quality Assurance Radiation Therapy Machine Output Checks The MD Anderson Radiation Dosimetry Services (RDS) provides independent peer reviews of beam output for radiation dose delivery systems. Specifically, we provide output checks for external beam radiation therapy machines including: megavoltage photon (2 - 25 MV) electron (4 - 20 MeV) orthovoltage (1.9 mm Al - 3 mm Cu HVL) Cobalt-60 Absorbed Dose in Blood Irradiators Thermoluminescent dosimeters (TLD) are available by mail to check the absorbed dose to the blood in irradiators used by blood banks. Packets of dosimeters are supplied; these can be placed at various locations to monitor the range of dose throughout the canister for a typical irradiation. These measurements are an independent check of the calibration of the blood irradiator as provided by the manufacturer. Radiation Dosimetry Services also offers checks of: total body dosimetry total skin dosimetry

6565 MD Anderson Blvd. Room Z4.2040 Houston, , TX , 77030 United StatesOur Mission The RPPA Core provides investigators with a powerful, high‐throughput, quantitative, cost‐effective technology for functional proteomics studies. Furthermore, we provide centralized, standardized and quality-controlled services to investigators not only throughout MD Anderson, but around the world, as well as to several national consortia, including TCGA, CCLE and ICBP. Our Method RPPA represents an antibody‐based functional proteomic analysis for both tumor tissue and cultured cells. RPPA characterizes the basal protein expression and modification levels, growth factor‐ or ligand‐induced effects, and time‐resolved responses appropriate for systems biology analysis. It provides information to integrate the consequence of genetic aberrations in cancer, to validate therapeutic targets, to demonstrate on‐ and off‐target activity of drugs, and to evaluate drug pharmacodynamics.

6565 MD Anderson Blvd. Room Z4.2040 Houston, TX 77030Our Mission The RPPA Core provides investigators with a powerful, high‐throughput, quantitative, cost‐effective technology for functional proteomics studies. Furthermore, we provide centralized, standardized and quality-controlled services to investigators not only throughout MD Anderson, but around the world, as well as to several national consortia, including TCGA, CCLE and ICBP. Our Method RPPA represents an antibody‐based functional proteomic analysis for both tumor tissue and cultured cells. RPPA characterizes the basal protein expression and modification levels, growth factor‐ or ligand‐induced effects, and time‐resolved responses appropriate for systems biology analysis. It provides information to integrate the consequence of genetic aberrations in cancer, to validate therapeutic targets, to demonstrate on‐ and off‐target activity of drugs, and to evaluate drug pharmacodynamics.

6565 MD Anderson Blvd. Room Z4.2040 Houston, , TX, 77030 United StatesOur Mission The RPPA Core provides investigators with a powerful, high‐throughput, quantitative, cost‐effective technology for functional proteomics studies. Furthermore, we provide centralized, standardized and quality-controlled services to investigators not only throughout MD Anderson, but around the world, as well as to several national consortia, including TCGA, CCLE and ICBP. Our Method RPPA represents an antibody‐based functional proteomic analysis for both tumor tissue and cultured cells. RPPA characterizes the basal protein expression and modification levels, growth factor‐ or ligand‐induced effects, and time‐resolved responses appropriate for systems biology analysis. It provides information to integrate the consequence of genetic aberrations in cancer, to validate therapeutic targets, to demonstrate on‐ and off‐target activity of drugs, and to evaluate drug pharmacodynamics.

Houston TX 77030 USAThe CCSG-supported Genomics Facility (GF) and the DNA Analysis Facility (DAF) have consolidated their activities to form a comprehensive institutional genomics shared resource: the Sequencing and Microarray Facility (SMF). The consolidated facility has combined the expertise of two existing facilities to provide investigators with sequencing, microarray and other SMF services. Sequencing services include: Next generation sequencing Sanger DNA sequencing Gene resequencing Microarray Services Target preparation, hybridization and imaging on the following platforms: Affymetrix Illumina Other SMF Services Sample quality check (DNA and RNA) Fluorescent fragment analysis Taqman-based gene expression analysis Project Consultation In addition to the standard services, the SMF provides custom services tailored to the individual needs of the investigator. Custom services include: Project design and technology consultations, Assay design and optimization and Assistance with result interpretation.

Houston, TX, 77030 United StatesThe CCSG-supported Genomics Facility (GF) and the DNA Analysis Facility (DAF) have consolidated their activities to form a comprehensive institutional genomics shared resource: the Sequencing and Microarray Facility (SMF). The consolidated facility has combined the expertise of two existing facilities to provide investigators with sequencing, microarray and other SMF services. Sequencing services include: Next generation sequencing Sanger DNA sequencing Gene resequencing Microarray Services Target preparation, hybridization and imaging on the following platforms: Affymetrix Illumina Other SMF Services Sample quality check (DNA and RNA) Fluorescent fragment analysis Taqman-based gene expression analysis Project Consultation In addition to the standard services, the SMF provides custom services tailored to the individual needs of the investigator. Custom services include: Project design and technology consultations, Assay design and optimization and Assistance with result interpretation.

Department of Experimental Therapeutics -- Unit 1950 The University of Texas MD Anderson Cancer Center P.O. Box 301429 Houston, TX 77230-1429The Sequencing and Non-coding RNA Program, a service of the Center for Targeted Therapy, offers MD Anderson investigators cutting-edge, emerging technology and expertise in functional genomics for the discovery of new non-coding RNAs (ncRNA) and expression profiling for known ncRNAs to further their cancer research. Primary Services SOLiD™ System/Ion Proton A “next generation” genome sequencing technology platform that provides broad applications for various forms of genome sequencing; gene expression, epigenetic and transcriptome profiling; and small RNA discovery. Applications include: whole genome sequencing; targeted genome re-sequencing; whole transcriptome, small RNA and mRNA expression sequencing and profiling; de novo sequencing; ChIP-sequencing; and epigenetic methylation sequencing and profiling. No other institution, at this time, is utilizing this technology as a service for its scientists. ncRNA/miRNA Expression Array Profiling Conducted on in-house microarray platforms and has the capacity to profile up to approximately 48 samples per week. The program’s director, Chang-gong Liu, Ph.D., developed the first-ever ncRNA/miRNA microarray platform. Full-service support for all Affymetrix GeneChip® microarray technology including genome-wide mRNA expression profiling, SNP genotyping and ChIP-on-Chip, to name but a few. Turnaround time is approximately three-to-five days. Support gene expression quantitation and the detection of SNPs utilizing the Applied Biosystems Fast Real-Time PCR System with a turnaround time of approximately two-to-three hours. Within one hour, the program can provide quantification and analysis of DNA, RNA, proteins and cells with the Agilent 2100 Bioanalyzer and the Thermo Scientific NanoDrop™ 1000 Spectrophotometer.

Department of Experimental Therapeutics -- Unit 1950 Houston, , TX, 77230-1429 United StatesThe Sequencing and Non-coding RNA Program, a service of the Center for Targeted Therapy, offers MD Anderson investigators cutting-edge, emerging technology and expertise in functional genomics for the discovery of new non-coding RNAs (ncRNA) and expression profiling for known ncRNAs to further their cancer research. Primary Services SOLiD™ System/Ion Proton A “next generation” genome sequencing technology platform that provides broad applications for various forms of genome sequencing; gene expression, epigenetic and transcriptome profiling; and small RNA discovery. Applications include: whole genome sequencing; targeted genome re-sequencing; whole transcriptome, small RNA and mRNA expression sequencing and profiling; de novo sequencing; ChIP-sequencing; and epigenetic methylation sequencing and profiling. No other institution, at this time, is utilizing this technology as a service for its scientists. ncRNA/miRNA Expression Array Profiling Conducted on in-house microarray platforms and has the capacity to profile up to approximately 48 samples per week. The program’s director, Chang-gong Liu, Ph.D., developed the first-ever ncRNA/miRNA microarray platform. Full-service support for all Affymetrix GeneChip® microarray technology including genome-wide mRNA expression profiling, SNP genotyping and ChIP-on-Chip, to name but a few. Turnaround time is approximately three-to-five days. Support gene expression quantitation and the detection of SNPs utilizing the Applied Biosystems Fast Real-Time PCR System with a turnaround time of approximately two-to-three hours. Within one hour, the program can provide quantification and analysis of DNA, RNA, proteins and cells with the Agilent 2100 Bioanalyzer and the Thermo Scientific NanoDrop™ 1000 Spectrophotometer.

Department of Experimental Therapeutics -- Unit 1950 Houston, , TX , 77230-1429 United StatesThe Sequencing and Non-coding RNA Program, a service of the Center for Targeted Therapy, offers MD Anderson investigators cutting-edge, emerging technology and expertise in functional genomics for the discovery of new non-coding RNAs (ncRNA) and expression profiling for known ncRNAs to further their cancer research. Primary Services SOLiD™ System/Ion Proton A “next generation” genome sequencing technology platform that provides broad applications for various forms of genome sequencing; gene expression, epigenetic and transcriptome profiling; and small RNA discovery. Applications include: whole genome sequencing; targeted genome re-sequencing; whole transcriptome, small RNA and mRNA expression sequencing and profiling; de novo sequencing; ChIP-sequencing; and epigenetic methylation sequencing and profiling. No other institution, at this time, is utilizing this technology as a service for its scientists. ncRNA/miRNA Expression Array Profiling Conducted on in-house microarray platforms and has the capacity to profile up to approximately 48 samples per week. The program’s director, Chang-gong Liu, Ph.D., developed the first-ever ncRNA/miRNA microarray platform. Full-service support for all Affymetrix GeneChip® microarray technology including genome-wide mRNA expression profiling, SNP genotyping and ChIP-on-Chip, to name but a few. Turnaround time is approximately three-to-five days. Support gene expression quantitation and the detection of SNPs utilizing the Applied Biosystems Fast Real-Time PCR System with a turnaround time of approximately two-to-three hours. Within one hour, the program can provide quantification and analysis of DNA, RNA, proteins and cells with the Agilent 2100 Bioanalyzer and the Thermo Scientific NanoDrop™ 1000 Spectrophotometer.

Houston TX 77030 USAAll investigators interested in performing a High Throughput or a High content siRNA screen will be invited to a preliminary meeting with the staff of the screening service. During this meeting all essential details regarding the screen will be discussed including cell lines, assay design, standard operating procedure of a screen, time line, cost and cell culture models. We currently have the capability of performing high throughput screens in utilizing both 2D monolayer cell culture models and 3D spheroid cell culture models.

Houston , TX, 77030 United StatesAll investigators interested in performing a High Throughput or a High content siRNA screen will be invited to a preliminary meeting with the staff of the screening service. During this meeting all essential details regarding the screen will be discussed including cell lines, assay design, standard operating procedure of a screen, time line, cost and cell culture models. We currently have the capability of performing high throughput screens in utilizing both 2D monolayer cell culture models and 3D spheroid cell culture models.

Department of Imaging Physics 1515 Holcombe Boulevard -- Unit 56 Houston, , Texas , 77030-4009 United StatesThe Small Animal Imaging Facility (SAIF) is a core MD Anderson research resource. It was established in 2001, became part of and is partially funded by the Cancer Center Support Grant (CA16672, PI – DePinho). The SAIF team provides comprehensive imaging support services for MD Anderson cancer investigators, including: Assistance in experimental design Developing specialty equipment and innovative procedures for imaging Preparing animals for studies, inducing and maintaining appropriate anesthesia and immobilization of animals during imaging Processing and interpreting data for publication or grant preparation

Department of Imaging Physics 1515 Holcombe Boulevard -- Unit 56 Houston, Texas 77030-4009The Small Animal Imaging Facility (SAIF) is a core MD Anderson research resource. It was established in 2001, became part of and is partially funded by the Cancer Center Support Grant (CA16672, PI – DePinho). The SAIF team provides comprehensive imaging support services for MD Anderson cancer investigators, including: Assistance in experimental design Developing specialty equipment and innovative procedures for imaging Preparing animals for studies, inducing and maintaining appropriate anesthesia and immobilization of animals during imaging Processing and interpreting data for publication or grant preparation

1515 Holcombe Blvd., Box 448 Houston, , TX, 77030 United StatesThe functions of the Tissue Resources and Pathology Core facilities are to facilitate acquisition, preservation, analysis and utilization by researchers of clinical samples. The SPOREs listed below have specific information about their Cores and/or contact information.

1515 Holcombe Blvd., Box 448 Houston, , TX , 77030 United StatesThe functions of the Tissue Resources and Pathology Core facilities are to facilitate acquisition, preservation, analysis and utilization by researchers of clinical samples. The SPOREs listed below have specific information about their Cores and/or contact information.

1515 Holcombe Blvd., Box 448 Houston, TX 77030The functions of the Tissue Resources and Pathology Core facilities are to facilitate acquisition, preservation, analysis and utilization by researchers of clinical samples. The SPOREs listed below have specific information about their Cores and/or contact information.

1000 East James Street Baytown, TX, 77520 United StatesAccess diverse, multi-therapeutic human biospecimens—without the delays of traditional clinical trials. From infectious diseases to Alzheimer’s and beyond, Vexillum provides ready-to-ship inventory and rapid, customized collection programs. IRB-approved, globally scalable, and built for speed—so your research timelines stay on track. Vexillum, LLC, a subsidiary of KUR Research, is a trusted biospecimen partner to pharmaceutical, biotechnology, and diagnostic organizations seeking speed, reliability, and flexibility. Our multi-therapeutic biobank spans infectious diseases, neurodegenerative disorders (including Alzheimer’s disease), and a broad range of specialty indications—delivering timely access to high-quality, research-ready human samples. Core Capabilities: Rapid access to diverse biospecimens across multiple disease areas Prospective collection programs with fast startup timelines Broad specimen types: whole blood, serum, plasma, saliva, nasal and nasopharyngeal swabs, vaginal swabs, urine, and more Sourcing of healthy controls and hard-to-find patient populations Scalable site network including urgent care centers and private practices Vexillum currently holds numerous *infectious disease* biospecimens including *SARS-CoV-2*, *Influenza A*, and *Influenza B*. Our diverse site list allows us to easily collect *healthy control* samples for all your *research and development* needs. Not finding what you need in our banked specimens? Vexillum can easily begin a *biospecimen collection* to accommodate your specific needs. Our collection sites are *IRB approved* and ready to collect immediately. Vexillum protocol allows for the collection of various *Human Biospecimens* including *saliva*, *whole blood*, *serum*, *plasma*, *vaginal swabs*, *anterior nasal swabs*, *nasopharyngeal swabs*, *urine* and many more. A key demonstration of our execution capabilities includes the successful prospective collection of 1,000 donors with suspected acute upper respiratory infections within just 90 days. This was accomplished through a hybrid recruitment model integrating all-comers enrollment with targeted enrichment via standard-of-care rapid antigen testing, across KUR-affiliated urgent care centers and multidisciplinary private practices. What sets Vexillum apart? Speed and execution. We eliminate the bottlenecks of traditional procurement by offering both ready-to-ship banked specimens and fully customizable prospective collections through our pre-qualified, IRB-approved site network. All samples available for purchase are collected by trained and delegated clinical research staff utilizing an *IRB approved* protocol for specimen procurement. Each donor signs *IRB approved Informed Consent* prior to donation. Let us know how we can support your *research*, Vexillum is *making progress possible*.

Deison Technology Park (Headquarters) 10130 Deison Park Blvd. Conroe, Texas, 77303 United StatesPlasmid DNA (pDNA) Manufacturing - In as Little as 7 Days VGXI is a leader in plasmid DNA contract manufacturing, with 20+ years of experience providing high quality products to biomedical researchers worldwide. We support clients that develop DNA vaccines, immunotherapies, cell therapies, and gene therapies. VGXI’s manufacturing process and quality controls are coupled to a continuous, low-shear AIRMIX® patented lysis technology, and optimized purification processes that provide highly supercoiled plasmid and exceptional purity. VGXI’s portfolio includes high quality plasmid for preclinical research, Highly Documented (HD) plasmid as a critical raw material for GMP viral vector production or pharm/tox studies, cGMP plasmid DNA for clinical through commercial supply, and custom services. Benefits: - Available slots for immediate and near-term manufacturing from newly established manufacturing capacity - Best-in-class quality and regulatory expertise from vertically integrated and qualified systems - Custom scales and yield optimizations to meet your most challenging program

Deison Technology Park (Headquarters) 10130 Deison Park Blvd. Conroe, TX, 77303 United StatesPlasmid DNA (pDNA) Manufacturing - In as Little as 7 Days VGXI is a leader in plasmid DNA contract manufacturing, with 20+ years of experience providing high quality products to biomedical researchers worldwide. We support clients that develop DNA vaccines, immunotherapies, cell therapies, and gene therapies. VGXI’s manufacturing process and quality controls are coupled to a continuous, low-shear AIRMIX® patented lysis technology, and optimized purification processes that provide highly supercoiled plasmid and exceptional purity. VGXI’s portfolio includes high quality plasmid for preclinical research, Highly Documented (HD) plasmid as a critical raw material for GMP viral vector production or pharm/tox studies, cGMP plasmid DNA for clinical through commercial supply, and custom services. Benefits: - Available slots for immediate and near-term manufacturing from newly established manufacturing capacity - Best-in-class quality and regulatory expertise from vertically integrated and qualified systems - Custom scales and yield optimizations to meet your most challenging program

2700 Research Forest Drive,Plasmid DNA (pDNA) Manufacturing - In as Little as 7 Days VGXI is a leader in plasmid DNA contract manufacturing, with 20+ years of experience providing high quality products to biomedical researchers worldwide. We support clients that develop DNA vaccines, immunotherapies, cell therapies, and gene therapies. VGXI’s manufacturing process and quality controls are coupled to a continuous, low-shear AIRMIX® patented lysis technology, and optimized purification processes that provide highly supercoiled plasmid and exceptional purity. VGXI’s portfolio includes high quality plasmid for preclinical research, Highly Documented (HD) plasmid as a critical raw material for GMP viral vector production or pharm/tox studies, cGMP plasmid DNA for clinical through commercial supply, and custom services. Benefits: - Available slots for immediate and near-term manufacturing from newly established manufacturing capacity - Best-in-class quality and regulatory expertise from vertically integrated and qualified systems - Custom scales and yield optimizations to meet your most challenging program

8300 Cypress Creek Parkway Suite 100 Houston, TX, 77070 United StatesAt Virovek, our mission is to provide our customers with the best AAV products on the market for their research and development projects. Our team is dedicated to providing exceptional customer service. All of our experienced personnel are here to help you achieve your goals of gene expression in a timeliness manner. When you are ready to move on to the next clinical stage, we can provide GLP grade products and offer our licensing options available for GMP-grade high titer to guarantee a high-capacity production with our novel patented BAC-to-AAV technology. This technology has been used by our customers and partners in clinical trials across the world and in FDA-approved gene therapies in the United States. AAV PRODUCTION: We offer a variety of custom-made adeno-associated virus (AAV) production in our patented baculovirus systems at 1E+13 to 1E+17vg/ml scale in a variety of serotypes: AAV1, 2, 3A/B, 4, 5, 6, 7, 8, 9, PHP.eB, rh10, 2.7m8, DJ, MYO, 2.retro, and other genetically modified capsids. We can transform your own engineered capsids into our Bac-to-AAV system and deliver similar yields to the WT counterparts. VIRAL VECTOR PRODUCTION: Virovek offers AAV productions perform by the traditional method, triple plasmid transfection in HEK293, at your request. Virovek provides other viral vector productions, such as Lentivirus, Adenovirus, and Baculovirus. All viral vector productions can be delivered within 2-5 weeks. ADDITONAL SERVICES: We offer vector design and construction, gene synthesis, DNA miniprep/maxiprep, and a variety of quality control assay services for your convenience. Some quality control assays we provide detect Full and Empty viral ratios, Endotoxin Levels, Osmolarity, Aggregation, Infectivity titer, Capsid titer, dPCR titer, sterility, and more. AAV STANDARD CONTROLS: Virovek can provide pre-made AAV you can use as controls in your study. We have CMV-GFP, CMV-mCherry, CMV-Luciferase (firefly), CMV-LacZ, CAG-GFP, hSYN-GFP, CMV-Cre, CMV-Cre-P2A-GFP, empty capsids, and more that are packaged in a variety of serotypes mentioned above. These products can be delivered to you within 1-5 business days. info@virovek.com | www.virovek.com Virovek is BSL-2 certified GLP compliant facility and all services are performed in Houston, TX, United States.

16403 Marrat Ct Tomball, TX, 77377 8438 United StatesVPrep Corp specializes in providing expert consulting and precision elemental analysis testing services tailored for industries utilizing X-ray Fluorescence (XRF) and Optical Emission Spectroscopy (OES) technologies. Our services support manufacturers, laboratories, and quality assurance teams in achieving accurate, reliable results. Consulting Services: Method development and optimization for XRF/OES applications Calibration standards guidance and implementation Regulatory compliance support (e.g., ASTM, ISO, RoHS) Troubleshooting and technical support for instrument performance Staff training and operational best practices Elemental Analysis Testing Services: High-precision material composition analysis Sample testing using industry-leading XRF instrumentation Trace element detection and quantification Rapid turnaround for industrial and R&D applications Data interpretation and reporting tailored to client needs

16403 Marrat Ct TOMBALL, TX, 77377 United StatesVPrep Corp specializes in providing expert consulting and precision elemental analysis testing services tailored for industries utilizing X-ray Fluorescence (XRF) and Optical Emission Spectroscopy (OES) technologies. Our services support manufacturers, laboratories, and quality assurance teams in achieving accurate, reliable results. Consulting Services: Method development and optimization for XRF/OES applications Calibration standards guidance and implementation Regulatory compliance support (e.g., ASTM, ISO, RoHS) Troubleshooting and technical support for instrument performance Staff training and operational best practices Elemental Analysis Testing Services: High-precision material composition analysis Sample testing using industry-leading XRF instrumentation Trace element detection and quantification Rapid turnaround for industrial and R&D applications Data interpretation and reporting tailored to client needs

7505 Fannin Street Houston, TX, 77054 United StatesWatsonbio s dedicated to provide worldwide life science researchers with superior quality service. We provide a comprehensive portfolio of custom services, including recombinant protein, antibody, stable cell lines services. Instead of a provider of services, we are a partner who can be relied on and who will work with you to design customized solutions for your project, to advance your research, and to accelerate your results.

1220 Capitol CourtWisconsin National Primate Research Center focuses on research of regenerative medicine, reproduction, immunology, virology, aging, and metabolic diseases.