Am Mittleren Moos 48 Augsburg, Bavaria, 86167 GermanyAnalytical Services in LC-MS/MS, GC-MS, SFC-MS/MS and Mass Spectrometric Non-Target Screening and Consultants in that field

Am Mittleren Moos 48 Augsburg, Bavaria, 86167 GermanyAnalytical Services in LC-MS/MS, GC-MS, SFC-MS/MS and Mass Spectrometric Non-Target Screening and Consultants in that field

Otto-Hahn-Str. 15 Dortmund 44227 GermanyInterMed Discovery provides screening samples, compounds, production facilities, and data systems.

Dortmund, NRW GermanyInterMed Discovery provides screening samples, compounds, production facilities, and data systems.

Am Klopferspitz 19 Martinsried, Planegg 82152 GermanyCompany Overview ibidi is a leading supplier for functional cell-based assays and advanced products for cellular microscopy. ibidi is located in Martinsried, Germany, close to Munich and the US headquarters, ibidi USA Inc., is located in Madison, Wisconsin. Our Mission The cell is the basic unit of biological organisms, including humans. Our technologies support researchers in the fields of biology, medicine, and pharmaceutics, allowing them to push their knowledge forward in the field of living cells. The increasing know how of cell function and design enables researchers to understand the mechanisms of illnesses, such as cancer and atherosclerosis, and therefore develop drugs in a targeted way. Our mission is to enable our customers to achieve outstanding success and breakthroughs in life sciences, pharma, biotechnology and medical diagnostics. We thereby are helping to make improvements in life possible. Our commitment to the markets and clients we serve drives our innovation and leadership in all areas where our assay technologies are required. Our customers are seen as partners whose invaluable feedback has a strong influence on our development of new solutions for their needs and problems. New product development at ibidi is handled by a close knit team of physicists, biologists and engineers. The exceptional talent, skill, and passion of our employees continue to be the key to ibidi’s excellence and success.

GermanyCompany Overview ibidi is a leading supplier for functional cell-based assays and advanced products for cellular microscopy. ibidi is located in Martinsried, Germany, close to Munich and the US headquarters, ibidi USA Inc., is located in Madison, Wisconsin. Our Mission The cell is the basic unit of biological organisms, including humans. Our technologies support researchers in the fields of biology, medicine, and pharmaceutics, allowing them to push their knowledge forward in the field of living cells. The increasing know how of cell function and design enables researchers to understand the mechanisms of illnesses, such as cancer and atherosclerosis, and therefore develop drugs in a targeted way. Our mission is to enable our customers to achieve outstanding success and breakthroughs in life sciences, pharma, biotechnology and medical diagnostics. We thereby are helping to make improvements in life possible. Our commitment to the markets and clients we serve drives our innovation and leadership in all areas where our assay technologies are required. Our customers are seen as partners whose invaluable feedback has a strong influence on our development of new solutions for their needs and problems. New product development at ibidi is handled by a close knit team of physicists, biologists and engineers. The exceptional talent, skill, and passion of our employees continue to be the key to ibidi’s excellence and success.

WolfenORGANICA Feinchemie offers custom synthesis of organic intermediates.

Bitterfeld-Wolfen, SA GermanyORGANICA Feinchemie offers custom synthesis of organic intermediates.

Koenigstrasse 4A Hamburg, HH, 22767 GermanyWe are AmpTec an internationally leading provider of RNA technology products, including synthetic long RNAs and DNAs, as well as functional mRNAs. We are committed to direct and flexible customer interactions with life science industries and academic research institutions around the world, including on-site technical support.

4A Königstraße Hamburg, HH, 22767 GermanyWe are AmpTec an internationally leading provider of RNA technology products, including synthetic long RNAs and DNAs, as well as functional mRNAs. We are committed to direct and flexible customer interactions with life science industries and academic research institutions around the world, including on-site technical support.

Hermannswerder Haus 17 Potsdam , 14473 GermanyAnalytiCon Discovery offers drug discovery services in the field of natural product ranging from the isolation/structure elucidation of natural products, their total synthesis and derivatization to target identification, assay development, screening and hit-to-lead optimization.

Hermannswerder Haus 17 14473 Potsdam , GermanyAnalytiCon Discovery offers drug discovery services in the field of natural product ranging from the isolation/structure elucidation of natural products, their total synthesis and derivatization to target identification, assay development, screening and hit-to-lead optimization.

Kirchstraße 19 II Berlin, Berlin, 10557 GermanyWe are a spin-off from Charité Berlin and the Technical University of Berlin and are developing AI algorithms for (histo)pathology.

Alt-Moabit 73/73A Berlin, Berlin, 10555 GermanyWe are a spin-off from Charité Berlin and the Technical University of Berlin and are developing AI algorithms for (histo)pathology.

Schumannstraße 17 Berlin, Berlin, 10117 GermanyWe are a spin-off from Charité Berlin and the Technical University of Berlin and are developing AI algorithms for (histo)pathology.

Schumannstraße 17 Berlin, 10117 GermanyWe are a spin-off from Charité Berlin and the Technical University of Berlin and are developing AI algorithms for (histo)pathology.

Gottfried-Hagen-Str. 60-62 Cologne, 51105 GermanyASAS is specialized in extractables/leachables analysis using high resolution LC-MS, structure elicidation and generation of reference standards, which are comerially not availabale like halogenated rubber oligomers.

Waltershofener Str. 17 79111 Freiburg, GermanyFounded in 1998, Aldevron is a recognized leader in contract development and manufacturing. Our custom services provide the basis for breakthroughs that enable clients to create the next generation of biological products. Our services include: • Plasmid DNA production meeting all quality standards from pre-clinical research through GMP. Our conserved process ensures consistency at all stages of development. • Therapeutic mRNA transcripts and gRNA for gene editing. We offer exceptional production flexibility and rapid turnaround times. • Protein design and manufacture that meet stringent quality and activity specifications. We support all quality grades, from research through GMP. • RG to GMP Cas9 nucleases, IVT enzymes for mRNA, and other enzymes tested for performance and evaluated by independent industry collaborators. Aldevron’s collaborative approach and commitment to quality allow us to meet precise client requirements and provide innovative solutions to advance science. Aldevron is headquartered in Fargo, North Dakota, and has additional facilities in Madison, Wisconsin.

Fritz-Hornschuch-Str. 9 Kulmbach, 95326 GermanyAxolabs is the leading Custom Research Organization for the discovery and preclinical drug development of oligonucleotide therapeutics and other nucleic acid medicines. Based on our world-leading know-how and 20 years of experience we provide high-end preclinical solutions tailored to our clients’ specific needs. As Axolabs is part of the LGC group Axolabs’ customers benefit from additional resources and expertise right across LGC, including a wide range of analytical services, leading capabilities in CMC, GMP and research-grade oligonucleotide manufacturing as well as custom synthesis of specialty phosphoramidites and solid supports.

Bahnhofstraße 86 Leipzig, 04158 GermanyAzenta Life Sciences provides unrivaled sample exploration and management solutions to help our customers accelerate discovery, development, and delivery to bring impactful breakthroughs and therapies to market faster. We are the global leader in automated compound management for drug discovery, biological storage, and sample processing solutions. Azenta understands the importance of sample integrity and provides a comprehensive range of solutions across our leading capabilities of genomic services, sample repository services (SRS), consumables and instruments, data management and informatics, sample sourcing, and automated ultra-cold storage.

Im Leuschnerpark 1b Griesheim, 64347 GermanyAzenta Life Sciences provides unrivaled sample exploration and management solutions to help our customers accelerate discovery, development, and delivery to bring impactful breakthroughs and therapies to market faster. We are the global leader in automated compound management for drug discovery, biological storage, and sample processing solutions. Azenta understands the importance of sample integrity and provides a comprehensive range of solutions across our leading capabilities of genomic services, sample repository services (SRS), consumables and instruments, data management and informatics, sample sourcing, and automated ultra-cold storage.

Osterfeldstraße 12-14 Hamburg, 22529 GermanyacCELLerate develops bioassays and provides assay ready Frozen Instant Cells. Frozen Instant Cells are cryopreserved at a highly functional state and are ready-to-use like a reagent. There is no need to expand or passage the cells before. By using assay ready Frozen Instant Cells, you will gain flexibility to schedule your experiments and increase the reproducibility and reliability of your bioassays. No matter if you are using cell based assays in high-throughput screening, toxicology assessment, clinical stage bioassays or post-marketing lot release.

Kirchstr. 1 15806 ZOSSEN GermanyAnagnosTec specializes in the development of novel MALDI-TOF mass spectrometrie techniques in the fields of biotechnology, clinical microbiology, industrial microbiology and food analysis.

Loerfeldstr. 20 58313 Herdecke, GermanyArdeypharm specializes in the development and production of microbial and herbal medicines.

GermanyABI Chem is a leading chemical provider of lab reagents, advanced intermediates, and contract chemical services. ABI Chem supports the Pharma, Biopharma, Agro, Specialty Chemical, Food, Nutritional and Nutraceutical industries. ABI Chem, through its worldwide representations, supports discovery of R&D and commercial manufactures through offering a wide range of products and reliable services.

Hermann Straße 46 ∙ Hamburg, 20095 GermanyFor 30 years, ACT successfully markets a growing number of raw materials of the highest, certified quality. Founded in 1985 in Hamburg by Dr. Ramin Ghaffari, ACT is now a larger company with internationally more than 60 employees. Our offices are located worldwide in the City of Hamburg as well as at 12 other locations. Successes are always achieved in the team, and every employee contributes with competence and initiative daily help. To globally operate successfully, we also have an international network of agents and strong partners for the important area of ​​logistics.

Darmstadt, HE GermanyAppliChem offers custom synthesis, cell culture media, reagent products and services.

Ottoweg 4 DE-64291 Darmstadt GermanyAppliChem offers custom synthesis, cell culture media, reagent products and services.

Munich, BY GermanyApceth offers GMP manufacturing services including cryopreservation, cell banking, stem cell expansion, cell products production, and quality control.

Max-Lebsche-Platz 30 Munich, D-81377 GermanyApceth offers GMP manufacturing services including cryopreservation, cell banking, stem cell expansion, cell products production, and quality control.

Am BioPark 11 Building 2 Regensburg, Bavaria, 93053 GermanyAssay.Works is a contract research organization (CRO) providing research services to pharmaceutical/biotech companies and academic organizations in form of fee-for-service work. Our mission is to accelerate our partner’s research programs by developing and executing predictive and scalable assays to quantify the bioactivity of novel chemical and biological entities. We combine scientific rigor with our domain expertise in laboratory automation, informatics, and industry best practices to turn challenging assays into quantitative, reproducible results. Our service portfolio includes Assay Development, Cell Line Engineering, Bioactivity Assessments, Quantitative Biology Applications, and High-Throughput Screening (HTS). Assay.Works builds on the 16-year legacy of a leading biopharma's HTS center where we provided assay, screening, and quantitative biology services for drug discovery programs across indications with high medical need.

Aroser Allee 68 Berlin, 13407 GermanyATLAS Biolabs offers expression profiling, SNP genotyping, karyotyping, DNA and RNA isolation, and bioinformatics services.

9B Joseph-Stelzmann-Straße c/o Max Planck Institute for biology of Ageing Köln, NRW, 50931 GermanyMax-Planck spin-off company performing target deconvolution by forward genetics. Unbiased identification of target structures at unmatched amino acid resolution mapping compound-target binding interfaces. Importantly our technology interrogates the entire genome including essential genes. Further applications of our platform technology include off-target identification and resistance prediction.

Eisackstr. 33 Berlin, 10827 GermanyAbovchem was founded by MedChem and CMC veterans to serve the Drug Discovery community. We are a part of BirdoTech Pharma Group and the platform of Catalog Reagent and Compound Management. We have ~160,000 building blocks in our catalog and offer a wide range of chemistry services from Discovery to CMC research and manufacturing. We strive to become your trusted chemistry partner. Our US office is located in sunny San Diego and we warehouse over 45k different research chemicals ready for next day delivery. The AbovChem vision is to help our clients realize maximum value, through our world-class innovation-driven drug discovery and manufacturing service platform. Our mission is to help you identify your next clinical candidates as soon as possible.

4 Rue Laurent Fries Illkirch-Graffenstaden, Grand Est, 67400 FranceAdvanced BioScience Laboratories, Inc (ABL) is an Institut Mérieux company ABL is a contract development and manufacturing organization (CDMO) specialized in developing and manufacturing viruses for vaccine candidates, gene, and cancer therapies. ABL's mission is to provide GMP viral vectors from early-stage clinical studies to commercialization, contributing to the success of its clients' immunotherapeutic innovations. ABL's CDMO services include bulk drug substance, fill/finish of drug product, process and assay development, and bioanalytical testing. ABL is a subsidiary of the Institut Mérieux and operates from various locations in Europe and the US. www.abl-biomanufacturing.com. ABL is also a contract research organization and leading global provider of immunology and biomarker analyses, offering expert laboratory & sample management services to advance promising candidates from discovery to the clinic. www.ablinc.com

Science Park 1 Saarbrücken, Saarland, 66123 GermanyAcross Barriers GmbH was set up with the aim to provide new technologies and services for the pharmaceutical, cosmetics and chemical industries in the research and development sector. In-vitro models of cell and tissue systems serve as the basis for the technology used simulating the transport of substances and formulations across biological barriers. In this process conclusions regarding permeability and absorption can be drawn. The clients of Across Barriers GmbH benefit from such studies in the following fields: - GLP and GMP certified. - Substances not suitable for development can be readily distinguished during the early phases and excluded at this point. - As a result time and financial costs accrued during the development of an active substance can be significantly lowered. - High-cost and ethically problematic animal experiments can also be reduced to a minimum. - In-vitro models permit the classification of formulations that can be administered via new forms, for example inhalation aerosols or transdermal application. In addition they allow mechanistic conclusions on the in-vivo behavior of substances. - Across Barriers has laboratories for biological and radioactive operations - Since 2003 the company has the permission to work with narcotics agents With the “in vitro bioequivalence” concept Across Barriers helps generic companies to avoid or reduce clinical studies Across Barriers supports its customer by answering a deficiency letter on the basis of in vitro studies Across Barriers is in the position to provide methods for classifying substances in accordance with the BCS guidelines regulated by the FDA, consequently offering the possibility of being released of in-vivo bio equivalence and in-vivo bioavailability studies. The use of tissue and cell cultures in the pre-clinic research consequently represents an intelligent and innovative step towards a faster, safer and less expensive development of modern active substances and formulations. Across Barriers develops and distributes validated models in order to secure an advantage in forward-looking technology for its clients.

1 Science Park Saarbrücken, SL, 66123 GermanyAcross Barriers GmbH was set up with the aim to provide new technologies and services for the pharmaceutical, cosmetics and chemical industries in the research and development sector. In-vitro models of cell and tissue systems serve as the basis for the technology used simulating the transport of substances and formulations across biological barriers. In this process conclusions regarding permeability and absorption can be drawn. The clients of Across Barriers GmbH benefit from such studies in the following fields: - GLP and GMP certified. - Substances not suitable for development can be readily distinguished during the early phases and excluded at this point. - As a result time and financial costs accrued during the development of an active substance can be significantly lowered. - High-cost and ethically problematic animal experiments can also be reduced to a minimum. - In-vitro models permit the classification of formulations that can be administered via new forms, for example inhalation aerosols or transdermal application. In addition they allow mechanistic conclusions on the in-vivo behavior of substances. - Across Barriers has laboratories for biological and radioactive operations - Since 2003 the company has the permission to work with narcotics agents With the “in vitro bioequivalence” concept Across Barriers helps generic companies to avoid or reduce clinical studies Across Barriers supports its customer by answering a deficiency letter on the basis of in vitro studies Across Barriers is in the position to provide methods for classifying substances in accordance with the BCS guidelines regulated by the FDA, consequently offering the possibility of being released of in-vivo bio equivalence and in-vivo bioavailability studies. The use of tissue and cell cultures in the pre-clinic research consequently represents an intelligent and innovative step towards a faster, safer and less expensive development of modern active substances and formulations. Across Barriers develops and distributes validated models in order to secure an advantage in forward-looking technology for its clients.

Planegger Str. 9a München, D-81241 GermanyAurigon is a preclinical CRO with offices in Munich and GLP-certified laboratories in Hungary. Aurigon possesses a spacious site for small and large animal testing (rodents, rabbits, dogs, minipig...) including in vitro laboratories close to the city borders of Budapest. Furthermore Aurigon maintains a well-equipped bioanalytical department in Budapest. The very heart of our company is our experienced and motivated staff, having up to 30 years of individual expertise. They are our excellent engine that enabled us to create a proven track record of more than 6000 studies, performed with a variety of test item classes (NCE, NBE, herbal extracts, vaccines, oligonucleotides…). In brief we are offering services in the field of: - Safety assessment: Safety pharmacology, hemocompatibility, in vivo toxicology, genotoxicity, Immunotoxicity. - ADME-PK: Pharmacokinetics, tissue distribution, metabolism studies, excretion studies. - Bioanalytics: bioanalytical method development and validation (ELISA, HPLC, LC-MS/MS…), quality control activities. - Pharmacodynamics: Glucose clamp test, glucose tolerance test and more models on request. For more detailed information about our broad service portfolio you may also visit our website (www.aurigon.eu).

Kopernikusstraße 6 Bergheim, 50126 GermanyA&M is focused in offering their expertise in bioanalytical and in vivo/in vitro ADME services.

Kopernikusstr. 25 Bergheim, NRW, 50126 GermanyA&M is focused in offering their expertise in bioanalytical and in vivo/in vitro ADME services.

BAV INSTITUTE Hygiene and Quality Assurance GmbH Hanns-Martin-Schleyer-Str. 25 77656 Offenburg

Bornbarch 16 22848 Norderstedt GermanyB.M.P. Pharma Trading offers delivery of raw materials to pharmaceutical, health-food and nutraceutical industries.

Norderstedt, SH GermanyB.M.P. Pharma Trading offers delivery of raw materials to pharmaceutical, health-food and nutraceutical industries.

Darmstädter Straße 34-36 64673 Zwingenberg GermanyTogether with strategic partners from the target industry, BRAIN has identified previously untapped, efficient enzymes, microbial producer organisms or natural substances from complex biological systems that can be put to industrial use. The company aims to replace classical chemical and industrial processes with novel and resource-saving processes, and to establish new processes and products.

Fraunhoferstrasse 13 D-82152 Martinsried GermanyBavarian Nordic focuses on developing product candidates to address cancer and infectious diseases by leveraging several core strengths: Revenue generating; consistent break even results Fully integrated R&D & manufacturing Two major pharma collaborations Differentiated pipeline in infectious diseases and oncology Approved discovery platform Through long-standing collaborations, including a collaboration with the U.S. government, Bavarian Nordic has developed a portfolio of vaccines for infectious diseases, including the non-replicating smallpox vaccine, IMVAMUNE®, which is stockpiled for emergency use by the United States and other governments. The vaccine is approved in the European Union (under the trade name IMVANEX®) and in Canada. Bavarian Nordic and its partner Janssen are developing an Ebola vaccine regimen, which has been fast-tracked, with the backing of worldwide health authorities, and a vaccine for the prevention and treatment of HPV. Additionally, in collaboration with the National Cancer Institute, Bavarian Nordic has developed a portfolio of active cancer immunotherapies, including PROSTVAC®, which is currently in Phase 3 clinical development for the treatment of advanced prostate cancer. The company has partnered with Bristol-Myers Squibb for the potential commercialization of PROSTVAC.

Halchtersche Strasse 33 D-38304 WolfenbuettelBIOBASE Biological Databases offers data collection and analysis, gene expression analysis, pathway modeling, and biological databases.

Building 56 Friedrich-Ebert-Strasse 75 51429 Bergisch Gladbach, GermanyWe know how it works! To know how something works is a high standard and we offer that to our customers. This understanding influences even the smallest of our actions. In the area of biocides (EU-biocide directive) we can offer years of experience in the development and testing of global brands. We are more than just a contract research organisation. We will help you to act in the right way at the right time. Our experience in project management puts you in a position to register your product successfully. We can advise you which active substances in which formulations have optimum efficacy against certain insect species without losing sight of issues like product safety and suitable packaging. We can show you exactly what works or doesn't.

Virchowstraße 10 c 78224 SingenOur laboratories are accredited according to DIN EN ISO / IEC 17025. A qualified team offers a broad range of investigations. These include microbiological, molecular biological and biochemical analysis of food, feed, consumer products, cosmetics, air, water and environmental samples. We also carry out hygiene inspections and -beratungen by all relevant institutions.

Tölzer Str. 12 Holzkirchen, 83607 Germanybioeq GmbH is a recently founded company which is located in Germany near Munich. The company is engaged in the development of biosimilar products. The products will be developed for global markets and will fulfil the standards of Europe, US and Japan.

Schelztorstraße 54-56 Esslingen, D – 73728 GermanyFor 15 years now, we at BioTeSys GmbH have been supporting companies in the fields of food, cosmetics and medical devices. With our longstanding expertise we check and secure your biological and chemical products and support you in questions related to bioactive ingredients. BioTeSys is a certified service provider w according to DIN ISO 9001:2008. BioTeSys offers chemical analysis, bioavailability studies, human studies, and in vitro assays to support analysis of biological functions of active ingredients.

Im Neuenheimer Feld 581 D-69120 Heidelberg GermanyBioCat GmbH, located in the Heidelberg Technology Park in close proximity to the German Cancer Research Center, is a privately held company founded in 2000 to market innovative products and services for life science research. BioCat offers a wide range of high-quality research reagents and instruments as well as cutting-edge technologies in the fields of genomics, proteomics and cell biology fueling science in academia as well as in pharma & biotech industry. We are committed to research and development to supply products with superior performance providing accurate, reliable and fast results. The products and services have been developed by our partners in Canada, Europe and the USA. Our experienced staff consists of Ph.D.-level scientists with a broad background in different life sciences disciplines to help you with any questions you may have about using our products in your research. At BioCat we are continuously striving to complement our product portfolio with novel products and technologies. When you are looking for a competent partner to sell your products to the life science research market in Germany, in Europe, or globally, please contact us.

Im Neuenheimer Feld 584 Heidelberg, 69120 GermanyBioCat GmbH, located in the Heidelberg Technology Park in close proximity to the German Cancer Research Center, is a privately held company founded in 2000 to market innovative products and services for life science research. BioCat offers a wide range of high-quality research reagents and instruments as well as cutting-edge technologies in the fields of genomics, proteomics and cell biology fueling science in academia as well as in pharma & biotech industry. We are committed to research and development to supply products with superior performance providing accurate, reliable and fast results. The products and services have been developed by our partners in Canada, Europe and the USA. Our experienced staff consists of Ph.D.-level scientists with a broad background in different life sciences disciplines to help you with any questions you may have about using our products in your research. At BioCat we are continuously striving to complement our product portfolio with novel products and technologies. When you are looking for a competent partner to sell your products to the life science research market in Germany, in Europe, or globally, please contact us.

An der Ziegelei 79 Sankt Augustin, 53757 GermanyBioSolveIT offers software to assist in structure-, ligand-, and fragment-based drug design. As your team of experts in computational chemistry we help your medicinal chemists excel. Access our medicinal chemistry expertise and industry leading software suite as a service, and accelerate your drug discovery. Working as an integrated part of your project team, we will use our decades of experience and deploy our proprietary solutions across the whole drug discovery process to help you achieve your goals. Do you have an in-house chemistry team looking for new inspiration, or an outsourced project team that needs support? Whether your needs are large or small, we would love to hear from you. Our solutions are tailored towards cracking the toughest nuts in small molecule discovery – from protein-protein interactions, overcoming toxicity and ADME issues, to understanding and visualizing selectivity - we will get you the answers you seek.

Ludwigshafen, RP GermanyBASF Competence Center Analytics offers chromatography, elemental analysis, spectroscopy, and physicochemical analysis services.

Köpenicker Straße 325 D-12555 Berlin GermanyBioGenes offers customized monoclonal and polyclonal antibody development and production, immunoassay development/pre-validation and protein analytical services. BioGenes is a market leader in custom HCP antibody development and characterization (1D-/2D-gels and Western blots for coverage analysis), DIGE analysis, Host Cell Protein ELISA development, pre-validation and production of ready-to-use ELISA kits. BioGenes supplier their customers also with specific anti-idiotypic antibodies (pAb or mAb) as tools for pharmacokinetic and immunogenicity studies. Corresponding specific ELISAs can be developed and qualified as custom service too. Quality Policy BioGenes GmbH We are certified according to ISO 9001-2015. To ensure the long-term fulfillment of specific customer requirements for our products and services, our Quality Management System complies with each requirement and specification of the internationally accepted DIN EN ISO 9001 guidelines since 1999. We follow a constant process of improvement and are audited annually by an independent certification company to maintain our certification status. Our laboratory performance meets high quality requirements and is based on the following principles: • Standardized work which follows SOPs • Traceable documentation of manufacturing and analytical services according to data integrity principles • Release testing of products by QC • Risk-based approach in Quality Management Processes • Experienced and well-trained personnel • Using qualified equipment • Conducting frequent internal and customer audits • Deploying animals and materials from certified and qualified suppliers Furthermore, BioGenes ensures that all services where work is carried out with and on animals meet specific animal welfare regulation, including but not limited to the following: • German Guidelines: Tierschutzgesetz (TierSchG), engl. Animal Welfare Act of 18th May 2006 (BGBl. I S. 1206), last update from 20th December 2022 • German Guidelines: Tierschutz-Versuchstierverordnung (TierSchVersV), engl. Animal Welfare Ordinance on Experimental Animals of 01 August 2013 (BGBl. I S. 3125), last update from 11th August 2021 • European Union Guidelines: EU Directive 2010/63 of 09th November 2010 and the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes of 18th March 1986

Köpenicker Str. 325 House 212 Berlin, Berlin, 12555 GermanyBioGenes offers customized monoclonal and polyclonal antibody development and production, immunoassay development/pre-validation and protein analytical services. BioGenes is a market leader in custom HCP antibody development and characterization (1D-/2D-gels and Western blots for coverage analysis), DIGE analysis, Host Cell Protein ELISA development, pre-validation and production of ready-to-use ELISA kits. BioGenes supplier their customers also with specific anti-idiotypic antibodies (pAb or mAb) as tools for pharmacokinetic and immunogenicity studies. Corresponding specific ELISAs can be developed and qualified as custom service too. Quality Policy BioGenes GmbH We are certified according to ISO 9001-2015. To ensure the long-term fulfillment of specific customer requirements for our products and services, our Quality Management System complies with each requirement and specification of the internationally accepted DIN EN ISO 9001 guidelines since 1999. We follow a constant process of improvement and are audited annually by an independent certification company to maintain our certification status. Our laboratory performance meets high quality requirements and is based on the following principles: • Standardized work which follows SOPs • Traceable documentation of manufacturing and analytical services according to data integrity principles • Release testing of products by QC • Risk-based approach in Quality Management Processes • Experienced and well-trained personnel • Using qualified equipment • Conducting frequent internal and customer audits • Deploying animals and materials from certified and qualified suppliers Furthermore, BioGenes ensures that all services where work is carried out with and on animals meet specific animal welfare regulation, including but not limited to the following: • German Guidelines: Tierschutzgesetz (TierSchG), engl. Animal Welfare Act of 18th May 2006 (BGBl. I S. 1206), last update from 20th December 2022 • German Guidelines: Tierschutz-Versuchstierverordnung (TierSchVersV), engl. Animal Welfare Ordinance on Experimental Animals of 01 August 2013 (BGBl. I S. 3125), last update from 11th August 2021 • European Union Guidelines: EU Directive 2010/63 of 09th November 2010 and the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes of 18th March 1986

Notkestr. 85, Geb 48e User Office L108, Attn. Tobias Graewert Hamburg, 22607 GermanyBIOSAXS GmbH utilizes the expertise of the SAXS group of the EMBL Hamburg, a recognized centre of excellence in synchrotron solution X-ray scattering. Access to the world's most brilliant synchrotron allows us complete sample characterization using 10 μl volumes and dilute concentrations (as low as 0.1 mg/ml). Our 96-well plate reader as part of the robotic sample changer combined with the automated data analysis pipeline supports high throughput screening. With our in-line size exclusion chromatography set-up equipped with light scattering, UV-absorption and refractometric detectors we offer a multipronged characterization of the different fractions within a sample.

Notkestr. 85, Geb. 25a, Hamburg, 22607 GermanyBIOSAXS GmbH utilizes the expertise of the SAXS group of the EMBL Hamburg, a recognized centre of excellence in synchrotron solution X-ray scattering. Access to the world's most brilliant synchrotron allows us complete sample characterization using 10 μl volumes and dilute concentrations (as low as 0.1 mg/ml). Our 96-well plate reader as part of the robotic sample changer combined with the automated data analysis pipeline supports high throughput screening. With our in-line size exclusion chromatography set-up equipped with light scattering, UV-absorption and refractometric detectors we offer a multipronged characterization of the different fractions within a sample.

Am Klopferspitz 19 Planegg, Bavaria, 82152 GermanyBicoll is an expert in the field of plant small molecules backed up by strong medicinal chemistry. Our focus is to deliver breakthrough solutions in pharmaceuticals, cosmetics, nutraceuticals, and agriculture. Bicoll has the proprietary right to the Bicoll Plant Profiles™, which provides the fastest and the most successful method to discover lead compounds from initial screening to animal tests or products. Bicoll offers solutions to hit to lead for drug discovery pipeline from scientifically gathered and carefully processed plant species with outstanding knowledge in high tech natural product chemistry to validated experience in medicinal chemistry. Bicoll offers time- and cost-effective medicinal chemistry services that are based on international standards for research, communication, and intellectual property. Our management team consists of experts with international business practice and renowned scientific experience. We provide medicinal chemistry services to our partners as an outsourcing solution, on project and FTE (full-time employee) basis. This can be for a variety of steps – for example for compound optimization, or medicinal chemistry consulting, in which your project data will be operated on FFS (fee for service) basis. Our effective outsourcing offers are customized to your requirements, are handled according to international standards

Am Klopferspitz 19 Planegg, Bavaria, 82152 GermanyBicoll is an expert in the field of plant small molecules backed up by strong medicinal chemistry. Our focus is to deliver breakthrough solutions in pharmaceuticals, cosmetics, nutraceuticals, and agriculture. Bicoll has the proprietary right to the Bicoll Plant Profiles™, which provides the fastest and the most successful method to discover lead compounds from initial screening to animal tests or products. Bicoll offers solutions to hit to lead for drug discovery pipeline from scientifically gathered and carefully processed plant species with outstanding knowledge in high tech natural product chemistry to validated experience in medicinal chemistry. Bicoll offers time- and cost-effective medicinal chemistry services that are based on international standards for research, communication, and intellectual property. Our management team consists of experts with international business practice and renowned scientific experience. We provide medicinal chemistry services to our partners as an outsourcing solution, on project and FTE (full-time employee) basis. This can be for a variety of steps – for example for compound optimization, or medicinal chemistry consulting, in which your project data will be operated on FFS (fee for service) basis. Our effective outsourcing offers are customized to your requirements, are handled according to international standards

C/O Wilmington Trust SP GmbH Steinweg 3-5 Frankfurt am Main, 60313 GermanyBioIVT, formerly BioreclamationIVT, is a leading global provider of high-quality biological specimens and value-added services. We specialize in control and disease state samples including human and animal tissues, cell products, blood and other biofluids. Our unmatched portfolio of clinical specimens directly supports precision medicine research and the effort to improve patient outcomes by coupling comprehensive clinical data with donor samples. And as the world’s premier supplier of ADME-toxicology model systems, including hepatocytes and subcellular fractions, BioIVT enables scientists to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and the effects on disease processes. By combining our technical expertise, exceptional customer service, and unparalleled access to biological specimens, BioIVT serves the research community as a trusted partner in ELEVATING SCIENCE. For more information about our processes on the regulatory oversight of Human Biological Specimens (HBS), please visit our website, www.bioivt.com, for more information. Specific information related to our quality and ethical assurances can be found here: https://www.bioivt.com/about/quality-assurance/.

Ullsteinstr. 108 Berlin, 12109 GermanyBerlinAnalytix supports preclinical and clinical studies to investigate the biocompatibility and efficacy of medical devices, following ISO 10993-6. Our focus includes histological processing of your biopsies, the specific application of histochemical and immunohistochemical staining methods, as well as histological, histopathological, and histomorphometric analysis, all the way up to MDR submission and publication.

Greifswald, MV GermanyBiometec is engaged in the development, production and distribution of research products for infection biology especially CD14, LBP and antibodies. In addition biometec offers a variety of laboratory and immunbiological services for academic institutes as well as pharmaceutical and biotechnological companies.

Radebeulstr. 1, 79219 Staufen, GermanyBilcare Research provides clinical supplies and packaging.

Jena, Thuringia GermanyCyBio develops, produces, sells and services pipetting and plate handling products.

Goeschwitzer Strasse 40 07745 Jena GermanyCyBio develops, produces, sells and services pipetting and plate handling products.

Zur Schönen Aussicht 26 D-07551 Zöllnitz GermanyBioMedical Instruments provides manufacturing of pipettes, microinjection devices, and consumables.

Universitätsstr. 25 Bielefeld, 33615 GERMANYBIBITEC GmbH is GMP-certified and specializes in the production of recombinant proteins and monoclonal antibodies for use in clinical trials up to phase III using mammalian cells.

Bielefeld, NRW GermanyBIBITEC GmbH is GMP-certified and specializes in the production of recombinant proteins and monoclonal antibodies for use in clinical trials up to phase III using mammalian cells.

31 Südkampen Walsrode, 29664 Germany

Building Q 30 51368 Leverkusen GermanyBayer HealthCare specializes in animal health, pharmaceuticals, consumer care and medical care.

Robert-Rössle-Straße Building 85, Level A2 Berlin, Berlin, 13125 GermanyBIOSYNTAN GmbH was founded in 1997 as a scientific service company focused on custom synthesis of peptides. An ever increasing interest in modified peptides has prompted us to develop novel manufacturing methods for such compounds. Today, as one of the leading specialists in the synthesis of linear and cyclic peptides having unusual residues and modifications, we are able to offer you an extensive and comprehensive range of services. Our core area is the manufacturing of fluorescently labeled peptides for assay development and the synthesis of post-translational modified peptides.

Robert-Roessle-Strasse 10 Berlin, 13125 GermanyBIOSYNTAN GmbH was founded in 1997 as a scientific service company focused on custom synthesis of peptides. An ever increasing interest in modified peptides has prompted us to develop novel manufacturing methods for such compounds. Today, as one of the leading specialists in the synthesis of linear and cyclic peptides having unusual residues and modifications, we are able to offer you an extensive and comprehensive range of services. Our core area is the manufacturing of fluorescently labeled peptides for assay development and the synthesis of post-translational modified peptides.

Kupferstraße 6 04827 Machern / OT Gerichshain, GermanyAs a reliable partner, we offer you comprehensive solutions with our services in the divisions of ecotoxicology, field testing and agricultural analytics in connection with the admission/registration of your products and active substances. Whatever you want to outsource in these areas – we can provide you the security you require – thanks to our twenty years of experience – so that your project feels to be in good hands. An active cooperation is the driving force behind our actions. Our range of services extends from the search for intelligent solutions to the use of specific test methods and most modern techniques to quality assurance and the desired cooperation with the competent authorities. You can rely on a precise result.

Kupferstraße 6 Machern / OT Gerichshain, 04827 GermanyAs a reliable partner, we offer you comprehensive solutions with our services in the divisions of ecotoxicology, field testing and agricultural analytics in connection with the admission/registration of your products and active substances. Whatever you want to outsource in these areas – we can provide you the security you require – thanks to our twenty years of experience – so that your project feels to be in good hands. An active cooperation is the driving force behind our actions. Our range of services extends from the search for intelligent solutions to the use of specific test methods and most modern techniques to quality assurance and the desired cooperation with the competent authorities. You can rely on a precise result.

Schorndorfer Strasse 32 70734 Fellbach GermanyBiosyn manufactures and markets a number of generic pharmacuetical products and more specifically the biopharmaceutical product Keyhole limpet hemocyanin (KLH).

Czernyring 22 69115 Heidelberg GermanyBiopharm offers analytics, spectroscopy, physicochemical testing, chromatography, bioassays, and cell culture.

Trippstadter Str. 110, D-67663 Kaiserslautern, Germany. Kaiserslautern, Trippstadter , D-67663 GermanyA leading manufacturer and supplier with more than 80,000 compounds in stock, scale-up manufacture, and custom services. With a wide range of ISO-certified laboratory chemicals, from heterocycles, boron acids, amino acids, and metal catalysts to chiral compounds, BLDPharm is ready for worldwide shipping.

Hans-Bunte-Starße 6 Heidelberg, Baden-Würtemberg, 69123 GermanyBiomex GmbH is a leading European supplier of human specimen: blood, plasma and tissue. Our product range includes bulk plasma for production, patient blood samples, prospective sample collection, panels for QC and human tissue. We also offer a range of services such as external studies, validation studies and CE certifications. Currently we are able to source SARS-CoV-2 (COVID-19) convalescent serum and plasma samples, bulk plasma, as well as panels and positive swabs. We also opened a new business for human tissue with various types of human FFPE tissue blocks - constantly growing.

Siemensstrasse 38 Heidelberg, BW, 69123 GermanyBiomex GmbH is a leading European supplier of human specimen: blood, plasma and tissue. Our product range includes bulk plasma for production, patient blood samples, prospective sample collection, panels for QC and human tissue. We also offer a range of services such as external studies, validation studies and CE certifications. Currently we are able to source SARS-CoV-2 (COVID-19) convalescent serum and plasma samples, bulk plasma, as well as panels and positive swabs. We also opened a new business for human tissue with various types of human FFPE tissue blocks - constantly growing.

Wilhelm-Mauser-Straße 41-43 Köln, Deutschland, 50827 GermanyBiotrend offers products for immunology, radiochemistry research, custom synthesis, and antibody production.

Carl-Braun-Strasse 1 34212 Melsungen, GermanyB. Braun offers biocompatibility testing, ophthalmic studies, microbiology, safety pharmacology, pharmacokinetics, metabolism, and manufacturing services.

An der Goldgrube 12 D-55131 Mainz GermanyBioNTech – Developing Revolutionary Treatments Our mission is to develop first-to-the-market next generation disruptive immunotherapies to revolutionize the treatment of cancer and other diseases. BioNTech is a fully integrated biotech company with all building blocks of immunotherapies under one roof and lab bench to market capabilities.

An der Goldgrube 12 Mainz, D-55131 GermanyBioNTech – Developing Revolutionary Treatments Our mission is to develop first-to-the-market next generation disruptive immunotherapies to revolutionize the treatment of cancer and other diseases. BioNTech is a fully integrated biotech company with all building blocks of immunotherapies under one roof and lab bench to market capabilities.

Ruffiniallee 15a Gräfelfing, 82166 GermanyBamOmaB supply monoclonal antibodies and ELISA kits developed in the Department of Immunology of the University of Tuebingen.

BLS Preclinical Services eK Postfach 191913 14008 BerlinBLS offers in vivo pharmacokinetic/pharmacodynamic studies, disease model studies, medical device testing, and isolated organ perfusion testing services.

Brommerstrasse 19 70563 Stuttgart 70563 Stuttgart GermanyBioLux offers polyclonal antibodies, custom DNA, and peptides.

Leonorenstr. 2-6 Berlin, 12247 GermanyBiochrom manufactures and distributes the full range of products related to mammalian cell culturing technique: standard cell culture media, complete media tailored for particular cell types and cell lines, custom formulations and animal sera, such as Fetal Bovine Serum (FBS).

Berlin, Berlin GermanyBiochrom manufactures and distributes the full range of products related to mammalian cell culturing technique: standard cell culture media, complete media tailored for particular cell types and cell lines, custom formulations and animal sera, such as Fetal Bovine Serum (FBS).

Stuttgarter Straße 130 D-71332 Waiblingen GermanyBased in Waiblingen near Stuttgart, Germany, and employing 6,200 associates, the Bosch Packaging Technology division is one of the leading suppliers of process and packaging technology. At over 30 locations in more than 15 countries worldwide, a highly-qualified workforce develops and produces complete solutions for the pharmaceuticals, food, and confectionery industries. These solutions are complemented by a comprehensive after-sales service portfolio. A global service and sales network provides customers with local points of contact.

Stuttgarter Straße 130 Waiblingen , D-71332 GermanyBased in Waiblingen near Stuttgart, Germany, and employing 6,200 associates, the Bosch Packaging Technology division is one of the leading suppliers of process and packaging technology. At over 30 locations in more than 15 countries worldwide, a highly-qualified workforce develops and produces complete solutions for the pharmaceuticals, food, and confectionery industries. These solutions are complemented by a comprehensive after-sales service portfolio. A global service and sales network provides customers with local points of contact.

Maximilianstrasse 10 68165 Mannheim, GermanyBENEO specializes in the production and supply of inulin, oligofructose, functional carbohydrates, sweeteners, and pharmaceutical excipients.

Im Neuenheimer Feld 515 Heidelberg, D – 69120 GermanyBioassay GmbH offers efficacy and safety testing services with the use of in vivo rodent and in vitro models.

Heidelberg, BW GermanyBioassay GmbH offers efficacy and safety testing services with the use of in vivo rodent and in vitro models.

19 Bitterfelder Straße Berlin, Berlin, 12681 GermanyBLS is a privately held preclinical contract research organization located in Berlin, in the heart of an environment that is unique in Europe; research and development is taking place in five universities, three university of applied sciences and in more than 20 research institutes. Berlin-Brandenburg has 30 pharmaceutical, 215 biotech and 280 medical device companies. More info. BLS serves the in vivo preclinical research needs of several international industries. The success of BLS research is attributed to effective teamwork among its employees and its network, who are committed to assuring that the company is the best in its field. BLS offers a wide range of high quality preclinical researches in vivo. BLS staff have extensive experiences of designing large and specialezed in vivo studies where untraditional ways to tackle problems. BLS works flexibly and adapts the studies to customer's project needs. Thereby, BLS takes care of the creativity needed to identify new and robust models for the preclinical phase. BLS's experience from small and large projects within many different diseases makes possible a fast and effective delivery of data to customers. Mission BLS exists to provide comprehensive in vivo research that meets the requirements of pharmaceutical, biotechnology, and medical device companies as we partner to bring safer products to the world. Our goal is to ensure responsive service while providing high quality and on-time research that is tailored to our sponsor’s need to discover, develop, enhance products in a state-of-the-art environment.

16 Fritz-Kotz-Straße Wiehl, NRW, 51674 GermanyAt BGS Beta-Gamma-Service, we specialize in radiation crosslinking and sterilization.

Robert-Koch-Str. 2 Planegg, Bavaria, 82152 Planegg GermanyBiomax is a global provider of tailored software solutions for the life sciences (pharma, biotechnology, agro) and healthcare. The unique technological features of our core product, the BioXM™ Knowledge Management Environment, allow highly complex questions to be addressed quickly, reliably and cost effectively. Biomax enables users to master the complex process of learning and leveraging how living systems function, change and evolve. We facilitate building knowledge through fully digital data and information management, semantic integration of heterogeneous data and tools, and systematic learning based on scientific evidence.

Garmischer Str. 4/V Munich, Bavaria, 80339 GermanyBioVariance as premium provider for bioinformatics services generates insights into complex biomedical datasets that lead to testable hypotheses for our customers. We bring your data into the right context by linking DNA, RNA, proteins, metabolites & more with known biological interactions and phenotypes, generating insights to the big picture of human biology and pharmacology. We use this as fundament for our analyses helping our customers to advance projects quicker and more targeted. Our analytis capabilities are supported by biomedical software development capabilities so that we can implement our pipelines very efficiently and also deploy them to our customers

BioZ, Johann-Krane Weg 42 Münster, 48149 GermanyBiomarker Technologies (BMKGENE) GmbH is an industry-leading genomics service provider, with Europe headquarter in Germany. We deliver professional Next Generation and de novo sequencing solutions for genomics, transcriptomics, epigenomics and metagenomics, with unrivalled efficiency, data quality and continuous technical support using the latest Illumina, PacBio and Nanopore platforms. Our most popular services could be cost-effective with fast turnaround time.

Munich, GermanyBSL BioService Scientific Laboratories offers toxicity services, bioanalytical services, microbiology, immunoanalytics, quality control, and ADME studies.

Fahrenheitstr. 4 Bremen, 28359 GermanyBruker Daltonics develops and offers instruments to support mass spectrometry analysis.

Morgenbreede 1 Bielefeld, NRW, 33615 GermanyBiofidus is specialized in the structural and functional characterization of proteins, viral vectors and small molecules. With more than 800 completed projects and supporting several big pharma clients as well as more than 70 pharmaceutical SMEs, Biofidus has gained vast experience with a wide analytical portfolio and comprehensive study designs. Key technologies: Mass spectrometry | chromatography | capillary electrophoresis | surface plasmon resonance | cell-based assays | next generation sequencing Key modalities: mAbs | bispecifics/multispecifics | ADCs | fusion proteins | nanobodies |enzymes | AAVs | VLPs Services in complex protein studies: - Initial protein characterization - Clone selection / lead selection - Developability assessment - Impurity characterization - Forced degradation studies - Stability testing - Comparability studies - Biosimilarity studies - Process characterization - Setup, transfer and qualification of analytical methods Analytical focus for proteins: - Primary structure - Amino acid modifications (oxidation, deamidation, isoaspartate etc.) - Glycosylation - Charge heterogeneity - Size heterogeneity - Purity - Higher order structure - Bioactivity studies / functional analysis Analytical focus for viral vectors like AAVs: - Complete genome sequencing incl. genome integrity - (AAV) Particle characterization incl. full/empty ratio and capsid PTMs - Vector quantification - Process related impurities - Product related impurities Analytical focus for small molecules: - Spent media analysis (nutrients, waste metabolites, etc.) - Surfactants / excipients - Small molecule based APIs - Antibiotics

Bothestrasse 142 Heidelberg, 69126 GermanyBiobyte Solutions provides customized bioinformatics services and tools including expertise in data analysis, resource integration and biological database maintenance.

Herterichstrasse 1 D-81479 MünchenBene-Arzneimittel GmbH offers manufacturing of quality goods and pharmaceutical drugs.

Schaffhausen Str 2-34 D-12099 Berlin GermanyPW Beyvers GmbH is specialized in the manufacture, testing, bottling and packaging of liquid and semisolid dosage forms of medicines and cosmetics.

Hermannswerder 17, 14473 Potsdam, GermanyOur service lab focuses on molecular and microbiological analyses. The laboratory is located in Potsdam, near Berlin, and services both domestic and international customers. We offer services to monitor the microbiological quality of pharmaceuticals, cosmetics and food. We also examine the effectiveness of disinfectants and aseptic filling machines using bioindicators and sell spore suspensions.

Im Neuenheimer Feld 267 Ruprecht-Karls-Universität Heidelberg Heidelberg, D-69120 GermanyBioQuant is the Center for “Quantitative Analysis of Molecular and Cellular Biosystems” at Heidelberg University, offering their RNAi screening and tissue imaging and analysis facilities to support research.

Heidelberg, BW GermanyBioQuant is the Center for “Quantitative Analysis of Molecular and Cellular Biosystems” at Heidelberg University, offering their RNAi screening and tissue imaging and analysis facilities to support research.

Charité - Universitätsmedizin Berlin Campus Virchow-Klinikum Augustenburger Platz 1 (Südstraße 2) D-13353 Berlin GermanyBerlin-Brandenburg Center for Regenerative Therapies provides preclinical, clinical, and regulatory services.

Berlin, Berlin GermanyBerlin-Brandenburg Center for Regenerative Therapies provides preclinical, clinical, and regulatory services.

Koblenzer Str. 65 50968 Koeln GermanyBOLDER Arzneimittel specialize in the development and manufacture of pharmaceutical pastilles.

Cologne, NRW GermanyBOLDER Arzneimittel specialize in the development and manufacture of pharmaceutical pastilles.

Offenburg, Germany BMG LABTECH has been committed to producing microplate readers for more than twenty years. By focusing on the needs of the scientific community, the company’s innovative microplate readers have earned the company the reputation of being a technology leader in the field. BMG LABTECH has developed a wide range of dedicated and multi-mode microplate readers for life sciences applications and high-throughput screening. All BMG LABTECH microplate readers are "Made in Germany" and are conceived, developed, assembled, and tested entirely at our headquarters in Germany. Since our establishment in Offenburg, Germany in 1989, BMG LABTECH has expanded to offer a worldwide sales and support network with offices in the USA, UK, Australia, Japan and France. Our subsidiaries, regional offices and distributors are committed to bringing you innovative microplate reader technology with the quality and reliability you expect from a German company. Our staff includes engineers and scientists from the fields of biology, biochemistry, analytical chemistry, and physics.

Allmendgrün 8 Ortenberg, Baden-Württemberg, 77999 Germany BMG LABTECH has been committed to producing microplate readers for more than twenty years. By focusing on the needs of the scientific community, the company’s innovative microplate readers have earned the company the reputation of being a technology leader in the field. BMG LABTECH has developed a wide range of dedicated and multi-mode microplate readers for life sciences applications and high-throughput screening. All BMG LABTECH microplate readers are "Made in Germany" and are conceived, developed, assembled, and tested entirely at our headquarters in Germany. Since our establishment in Offenburg, Germany in 1989, BMG LABTECH has expanded to offer a worldwide sales and support network with offices in the USA, UK, Australia, Japan and France. Our subsidiaries, regional offices and distributors are committed to bringing you innovative microplate reader technology with the quality and reliability you expect from a German company. Our staff includes engineers and scientists from the fields of biology, biochemistry, analytical chemistry, and physics.

Flughafendamm 9a Bremen, 28199 GermanyBiolog Life Science Institute supplies nucleosides, nucleotides, and analogues in addition to custom synthesis services.

Goldschmidtsraße 5 Heidelberg, 69115 GermanyBAST offers pharmacometric analysis services. BAST helps its clients advance their drug development programs by providing mathematical modelling and data analysis solutions. By supplying fit-for-purpose quantitative consultancy services we enable our clients to make informed decisions and mitigate risks.

Im Neuenheimer Feld 582 Heidelberg, 69120 GermanyBAST offers pharmacometric analysis services. BAST helps its clients advance their drug development programs by providing mathematical modelling and data analysis solutions. By supplying fit-for-purpose quantitative consultancy services we enable our clients to make informed decisions and mitigate risks.

Winkl 4 Dietersburg, Germany, 84378 GermanyTailored solutions for biological products and business development *Biophyll Top Seller* Bovine Serum Albumin Human Serum Albumin Animal Sera Dextran Human Plasma -------------------------------------------------------------------------------------------------------------------------------------- Biophyll is an expert in sourcing, manufacturing and developing of biological products of animal, human, and plant origin to provide tailored product solutions for pharmaceutical, diagnostic, and scientific purposes. 1. Listen to the needs of our customers  Tailored solutions for product and business development  Individually designed transport logistics concepts  Contact to international authorities on customers’ behalf  Recommendation for best product and service for the best price  Market screening and independent supplier evaluation 2. Worldwide network  Access to new and rare biological products sourced worldwide  Entry into new markets 3. Support with regulatory affairs  Supply/Check of quality and traceability documentation  Regulatory support in import, export, and registration matters 4. Additional services  Supply chain financing  TRACES registered European warehousing

DIARECT AG, Bötzinger Straße 29 B, 5 Semple Street Freiburg, 79111 GermanyBBI Solutions has served the global diagnostics industry for over 50 years, as a leading developer and manufacturer of raw materials and finished test platforms for the in-vitro diagnostics market. Over the past 50 years, BBI has grown from a small specialist company, to a global business with manufacturing sites in five different countries, spanning three continents. Our product ranges include: Biological Raw Materials Antigens Enzymes Monoclonal Antibodies and Recombinant Fab Antibodies Serum & Plasma Products Depleted Serum Disease State Plasma Normal Serum and Patient Samples In addition, we manufacture world renowned labels for lateral flow, ELISA assay and biosensors, these include: Gold Nanoparticles Horseradish Peroxidase and Glucose Oxidase BBI Solutions also offers end to end Contract Development and manufacturing services, with a core focus on custom gold conjugation and lateral flow test manufacture. Innovative new projects include the integration of emerging technologies into our products, such as the Novarum Smartphone Reader. BBI Solutions is part of the BBI Group www.the-bbigroup.com

10 Lademannbogen Hamburg, HH, 22339 GermanyBioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

10 Lademannbogen Hamburg, HH, 22339 GermanyBioAgilytix is a leading contract research organization specializing in large molecule needs, enabling scientific innovators to develop and deliver game-changing biologic innovations through our expertise in cell-based assays, biomarkers, immunogenicity, and pharmacokinetics (PK). We work scientist to scientist as a collaborative CRO partner to deliver integrated bioanalytical solutions for your toughest assay needs. In fact, we excel in some of the most demanding areas of bioanalysis today, where extensive, expert-level skill is required.

Im Neuenheimer Feld 515 Heidelberg, 69120 GermanyBioMed X is an independent research institute located on the campus of the University of Heidelberg in Germany, with a world-wide network of partner locations. In addition to our challenge-based external innovation model, we offer contract research services in the field of T cell receptor profiling for immunology discovery. Our expertise is a critical and complex component of the human adaptive immune system: the T lymphocyte. We have developed a proprietary technology platform that allows us to functionally identify and map cognate epitopes of human T cell receptors (TCRs) at unprecedented speed and accuracy. As a result, we can profile patient-derived TCR repertoires against large libraries of putative target epitopes. What is unique about our new technology platform? Identification of the target epitope(s) of a given T cell receptor (TCR) is a major challenge. In contrast to antibodies, which bind directly to their target, T cells recognize processed peptide epitopes presented by class I and II HLA molecules. Most attempts described in the literature to make this interaction amenable to high-throughput screening are based on engineered variants of the T cell receptors and/or peptide:HLA complexes, or a priori knowledge of the epitope and/or presenting HLA allele, limiting their ability to fully catalog physiologically relevant TCR:target interactions. In contrast, our new technology platform more closely represents the physiological processes underlying antigen processing, presentation, and ligand-induced T-cell activation. Our patent-pending platform consists of three major components: 1. T Cell Reporter Construct Our reporter cassette is designed such that any exogenous TCR or chimeric antigen receptor (CAR) can be inserted into the system. Based on a highly sensitive and specific synthetic promoter, engagement of the inserted receptor produces a fluorescent signal with an unprecedented signal-to-noise ratio easily detected by flow cytometry and/or microscopy. At the same time, the activated T cells produce a secreted label that binds to the cognate antigen-presenting cell(s). 2. Antigen-Presenting Cell Construct As a starting point for this construct, we use immortalized antigen-presenting cells from the TCR-autologous donor or our biobank, which currently covers approximately 80% of the most frequent HLA alleles. Following transduction with our patent-pending minigene library construct, these cells process and present peptides from the encoded antigens efficiently and persistently on both class I and II HLA. As a unique feature, we have identified and overcome a size limitation constraint on cDNA-derived antigen processing. As a result, we reliably achieve epitope presentation from open reading frames up to 400 amino acids in length, enabling library design that can feasibly cover the entire human reference proteome. 3. Phenotypic Screening Platform Next-generation sequencing of enriched target antigens is a powerful readout for high-throughput screening, but can be time-consuming and noisy. For targeted applications in which this is undesirable, we have developed a combinatorial phenotypic screening approach that unambiguously identifies the cognate target(s) with up to 98% first-pass confidence. This enables quick and cost-efficient profiling of TCRs against relatively large antigen libraries. What are potential applications? Our platform is particularly useful in biomedical research and drug discovery in oncology (tumor vaccines, targeted cancer immunotherapy, CAR-T, and TCR-T cell therapy), autoimmunity (autoantigen discovery, targeted immune modulation, regulatory TCR-T cell therapy), and infectious diseases (vaccines, chronic infection). Its modular design additionally provides the platform with the flexibility to easily incorporate alternative antigen-presenting cells, scales of throughput, and multiplexing options. Whenever the specificity of a T cell response in patients is of interest, our technology can provide valuable new insights. How can we support your research and development? Our preferred business model is to perform customized research projects on a fee-for-service basis. At the end of a project, our customers acquire full ownership of the results at pre-defined terms without the obligation of royalty or milestone payments. Potential Applications: - Fast, robust TCR discovery and characterization - Validation of predicted TCR:epitope interactions - Functional epitope mapping - Chimeric antigen receptor (CAR) evaluation - Safety profiling of TCR therapies - De novo TCR ligand identification, minimal epitope resolution - Customized TCR-based drug discovery programs

Ramskamp 47 25337 Elmshorn GermanyBioCell Technology is in the business of researching, developing, branding, and distributing novel dietary ingredients which are supported by science to improve quality of life in addition to offering custom product formulation and contract manufacturing services.

Hennigsdorf, GermanyBrahms offers biomarkers research, assays, and clinical research.

Rheinstetten, GermanyBruker Biospin offers analytical magnetic resonance instruments including NMR, preclinical MRI and EPR.

Dransfelder Weg 6 Dransfeld, 37127 GermanyBioviotica Naturstoffe produces biological active Natural Products (NP) derived from bacteria and fungi which are delivered to an international market.

Kirschallee 7 Michendorf, 14552 GermanyBioCol specializes in the research, production and distribution of in vitro research products for molecular and cellular laboratory medicine.

Hemmelrather Weg 201 D-51377 Leverkusen GermanyBiofrontera is a biopharmaceutical company specializing on the development of drugs and medicinal cosmetics for the treatment of skin diseases and the regenerative care of damaged skin.

Daimlerstraße 5b Karlsruhe, D-76185 GermanyBioChem offers analytical chemistry, microbiology, and toxicology testing services.

Karlsruhe, BW GermanyBioChem offers analytical chemistry, microbiology, and toxicology testing services.

Hamburg, HH GermanyBioskin offers clinical trials, consulting, data management, transdermals, and in vivo testing.

Czernyring 22 69115 Heidelberg, GermanyBIOMEVA offers API synthesis, microbial fermentation, protein purification, cell banking, and manufacturing services.

47 Stresemannallee Frankfurt am Main, HE, 60596 GermanyConsultant for Bioimage and Data processing. Proficient in: Computational:, Automated image analysis, Image quantification, 3D reconstruction of whole organs, Bioinformatics / Promoter analysis, Advanced programing and scripting, Whole-brain 3D comparison, mRNA quantification, Biostatistics Microscopy: Confocal and Multi-photon, Whole Brain Imaging (tomography), Automated Slide Scanners, Tissue Clearing CLARITY and iDISCO, Second-Harmonic Microscopy, and Super-resolution STED and STORM Bench: Mouse genetics and management, In vivo reporter assays, Numerous cloning systems, Generating ISH probes, High-throughput FISH / CISH, IHC (Fluorescent & Chromogenic), Mouse perfusion and organ collection, Cell culture (immortal and primary)

Heinrich-Plett-Str. 40 Geb. AVZ 2, Rm. 3125-3132 Kassel, HE, 34132 GermanyBiaffin specializes in biomolecular interaction analysis using surface plasmon resonance (SPR, Biacore) and offers kinetic binding studies of antibody, protein, peptide, small molecule and nucleic acid interactions by SPR.

Scharnhorststr. 24 Berlin, 10115 GermanyBelyntic is a chemistry for healthcare company. With our proprietary Peptide Easy Clean (PEC) technology, we provide a new solution for the manufacturing of chemically synthesized peptides and peptide nucleic acids (PNA). The PEC technology enables parallel purification, seamless upscaling as well as the manufacturing of next level peptide or PNA drugs through our unique platform. We provide synthesis service for peptides in different scale and number, kits, bulk, project services and more.

Richard-Willstaetter-Str. 11 Located at the Federal Institute of Material Testing (BAM) Berlin, Berlin, 12489 GermanyBelyntic is a chemistry for healthcare company. With our proprietary Peptide Easy Clean (PEC) technology, we provide a new solution for the manufacturing of chemically synthesized peptides and peptide nucleic acids (PNA). The PEC technology enables parallel purification, seamless upscaling as well as the manufacturing of next level peptide or PNA drugs through our unique platform. We provide synthesis service for peptides in different scale and number, kits, bulk, project services and more.

Kochstrasse 4 Trier, RLP, 54290 GermanyDesign and Communication Studio

Kochstrasse 4 Treir, RLP, 54290 GermanyDesign and Communication Studio

Kochstrasse 4 Treir, RLP, 54290 GermanyDesign and Communication Studio

Serumweg 48 Eystrup, 27324 GermanyThe Behring Campus Eystrup is a research facility with a focus on animal immunology and antibody development. We are highly customer-oriented in the design of immunization studies. Here we can work with a wide range of species. You can choose the complete service, from antigen up to the purified antibody, or individual work packages. Our offer is equally extensive in the provision of biological products with a broad selection of species and individually scalable batches. In addition, we offer our customers the possibility to carry out their preclinical projects in small and large animals. From planning to implementation of e. g. pharmacokinetic studies or preclinical contract research, we are always your reliable partner. Our service is particularly characterized by its high flexibility. The location of the former Behringinstitut Eystrup looks back on a veterinary and immunological past full of tradition. To this day, we continue this tradition with modern technology and successfully realize a wide variety of customer orders. Please do not hesitate to contact us. We are looking forward to your projects.

Kaiser-Wilhelm-Allee 50 51368 Leverkusen, Germany 0214 301Bayer Technology Services offers process design/evaluation and specializes in process, materials, and manufacturing technologies.

Leverkusen, NRW GermanyBayer Technology Services offers process design/evaluation and specializes in process, materials, and manufacturing technologies.

Moritzburger Weg 67 Dresden, Saxony, 01109 GermanyBiotype’s contract development & manufacturing service (Custom Solutions) covers all challenges from the idea up to the realization of a marketable product. As a European Molecular Diagnostic company and a proven OEM supplier, we are committed to high-quality standards and are able to accommodate individualized product specifications for our international customers. For more information visit our Custom Solutions Service page: https://custom-solutions.biotype.de

Moritzburger Weg 67 Dresden, 01109 GermanyBiotype’s contract development & manufacturing service (Custom Solutions) covers all challenges from the idea up to the realization of a marketable product. As a European Molecular Diagnostic company and a proven OEM supplier, we are committed to high-quality standards and are able to accommodate individualized product specifications for our international customers. For more information visit our Custom Solutions Service page: https://custom-solutions.biotype.de

Moritzburger Weg 67 Dresden, 01109 GermanyBiotype’s contract development & manufacturing service (Custom Solutions) covers all challenges from the idea up to the realization of a marketable product. As a European Molecular Diagnostic company and a proven OEM supplier, we are committed to high-quality standards and are able to accommodate individualized product specifications for our international customers. For more information visit our Custom Solutions Service page: https://custom-solutions.biotype.de

Merck Group Frankfurter Strasse 250 Darmstadt, Germany, 64293 GermanyBioReliance® is a brand business within the wider Merck KGaA, Darmstadt, Germany group. There are six franchises with the brand offering a wide range of services to support the Life Science Market; 1) BioReliance® Biosafety Testing Services, which provides Biologics Safety Testing, Biomanufacturing Services (Mammalian Cell Bank), Viral Clearance Studies and Lot Release testing of clinical and commercial material (bulk harvest, Drug substance and Drug Product) 2) BioReliance® Product Characterization Services, which provide product and process characterization services including physicochemical assays, binding and potency assays 3) BioReliance® Validation Testing Services providing validation services for selecting, testing and validating filters, assemblies and single-use systems for drug manufacturing. Services include Extractables and leachables testing, Bacteria retention testing, Integrity testing, Compatibility testing & Patient safety evaluations 4) BioReliance® End to End Services providing manufacturing services to accelerate clinical drug development, scale your process and implement local production facilities, globally. 5) BioReliance® Viral Vector Manufacturing provide contract manufacturing services for virus and gene therapy molecules

Campus Neuried Anna-Sigmund-Str. 5 Neuried, 82061 GermanyBio-Rad's custom antibody generation services can provide you with sequence defined, well-characterized, and application tested, non-animal-derived antibodies. Our recombinant antibodies are selected from the fully synthetic, naïve Human Combinatorial Antibody Libraries (HuCAL®) using a proprietary method of phage display. Fab antibodies are dispatched in as little as 8 weeks. Our latest innovation introduces SpyTag technology to the platform, to build antibodies from modules by protein ligation, and perform site-directed conjugation.

Zeppelinstrasse 4 Puchheim, 82178 GermanyBio-Rad's custom antibody generation services can provide you with sequence defined, well-characterized, and application tested, non-animal-derived antibodies. Our recombinant antibodies are selected from the fully synthetic, naïve Human Combinatorial Antibody Libraries (HuCAL®) using a proprietary method of phage display. Fab antibodies are dispatched in as little as 8 weeks. Our latest innovation introduces SpyTag technology to the platform, to build antibodies from modules by protein ligation, and perform site-directed conjugation.

CAMECA GmbH Carl-von-Linde-Str. 42 D-85716 Unterschleissheim/Munich

Berlin, GermanyCaprotec Bioanalytics provides tailored functional isolation of proteins, targeted analysis of small molecule-protein interactions, and identification of on-/off- targets.

Mühlenstr.1 • D-83064 Raubling, GermanyChrombios offers FISH, cloned DNA mapping, karyotyping, cell line characterization and chromosome sorting services.

57 Heinz-Fangman-Straße Wuppertal, NRW, 42287 GermanyPriorities of the company are services in the fields of dermatology, oncology, allergy, aesthetic medicine and cosmetic medicine. Model our Company activity "Non Major sed Melior" (not more but better) is the leitmotif of our work. Following Principle define our Action: The health and safety of our patients and volunteers at the beginning of all our considerations The principles of the Declaration of Helsinki of the World Medical Association and the principles of "Good Clinical Practice" (GCP) are the basis of our activity Personal commitment to the interests of our patients and volunteers at its best medical trade is our goal We give sufficient time in clinical trials and in the treatment of our patients Treatments are carried out by a, the patient known doctor - no treatment by repeatedly changing doctors

Carl-Zeiss-Strasse 22 Oberkochen, 73447 GermanyZEISS is an internationally leading technology enterprise operating in the optics and optoelectronics industries. The ZEISS Group develops and distributes semiconductor manufacturing equipment, measuring technology, microscopes, medical technology, eyeglass lenses, camera and cine lenses, binoculars and planetarium technology. With its solutions, the company constantly advances the world of optics and helps shape technological progress. ZEISS is divided up into the four segments Semiconductor Manufacturing Technology, Research & Quality Technology, Medical Technology, and Vision Care/Consumer Products. ZEISS is represented in over 40 countries and operates more than 30 production sites, over 50 sales and service locations and about 25 research and development facilities. In fiscal year 2014/15 the company generated revenue approximating €4.5 billion with around 25,000 employees. Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. Carl Zeiss AG is the strategic management holding company that manages the ZEISS Group. The company is wholly owned by the Carl Zeiss Foundation (Carl-Zeiss-Stiftung).

Göschwitzer Str. 51-52 07745 Jena GermanyZEISS is an internationally leading technology enterprise operating in the optics and optoelectronics industries. The ZEISS Group develops and distributes semiconductor manufacturing equipment, measuring technology, microscopes, medical technology, eyeglass lenses, camera and cine lenses, binoculars and planetarium technology. With its solutions, the company constantly advances the world of optics and helps shape technological progress. ZEISS is divided up into the four segments Semiconductor Manufacturing Technology, Research & Quality Technology, Medical Technology, and Vision Care/Consumer Products. ZEISS is represented in over 40 countries and operates more than 30 production sites, over 50 sales and service locations and about 25 research and development facilities. In fiscal year 2014/15 the company generated revenue approximating €4.5 billion with around 25,000 employees. Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. Carl Zeiss AG is the strategic management holding company that manages the ZEISS Group. The company is wholly owned by the Carl Zeiss Foundation (Carl-Zeiss-Stiftung).

Cologne, NRW GermanyCEVEC Pharmaceuticals offers cell line expression and expression protein products and services.

Gottfried-Hagen-Str. 62 51105 Köln GermanyCEVEC Pharmaceuticals offers cell line expression and expression protein products and services.

Augustenburgerplatz 1 Berlin, 13353 GermanyCharité - Universitätsmedizin Berlin focuses on research in many therapeutic areas.

Georges-Koehler-Allee 103 Freiburg, 79110 Germany

Neuhauser Str. 47 Munich, D-80331 GermanyConreso offers clinical research services including data management, clinical trial monitoring, and medical writing services.

Gasstrasse, 6 22761 Hamburg, GermanyChiesi farmaceutici offers drug development, drug discovery, and clinical trials.

Building Q 18 Leverkusen, 51368 GermanyCurrenta offers analytical chemistry, elemental analysis, and microbiology testing services.

Planegg, BY GermanyconoGenetix biosciences provides development of new peptide therapeutics for the treatment of autoimmune diseases.

Am Klopferspitz 19 82152 Martinsried/Planegg GermanyconoGenetix biosciences provides development of new peptide therapeutics for the treatment of autoimmune diseases.

Walther Rathenau Str. 49 a Greifswald, 17489 Germany

Walther Rathenau Str. 49 a Greifswald, 17489 Germany

Ainring, BY, 83404 Germany Chondrometrics GmbH (CHM) provides consultation, image data post-processing and image analysis services, focusing on quantitative analysis of articular cartilage morphology and structure from MRI data.

Ainring, Germany Chondrometrics GmbH (CHM) provides consultation, image data post-processing and image analysis services, focusing on quantitative analysis of articular cartilage morphology and structure from MRI data.

Berlin, Berlin GermanyManaging Cyanobacteria - all services relating to biotechnology with cyanobacteria: natural products, strain development, cultivation, extraction, cyanotoxin bioreagents and standards, analytical services

Magnusstraße 11 D-12489 Berlin GermanyManaging Cyanobacteria - all services relating to biotechnology with cyanobacteria: natural products, strain development, cultivation, extraction, cyanotoxin bioreagents and standards, analytical services

Robert-Roessle-Str. 10 Building D80 Berlin, 13125 GermanyThe celares GmbH is a drug delivery company focusing on the chemical modification/conjugation, in particular PEGylation of small molecules, peptides and proteins. The celares GmbH offers customized conjugation solutions on a fee for service basis. Services include the synthesis of tailor-made small molecules, activated reagents and polymers, process development for conjugation and purification, and the development of analytical methods for full characterization of bioconjugates. The celares GmbH has a clean room class D facility for the manufacturing of 0.5 to 5 kg of small molecules and activated intermediates, as well as for the preparation of conjugated drugs. A GMP certificate is issued by the local authorities. In addition, celares has developed proprietary platform technologies, namely celaSYS, celaSTAR, and PaSmax®. The latter technology is particularly useful for the development of next generation ADCs, based on payload solubilization and multiplexing. Clients are international biotech and pharma companies.

10 Robert-Rössle-Straße Building D79 Berlin, Berlin, 13125 GermanyThe celares GmbH is a drug delivery company focusing on the chemical modification/conjugation, in particular PEGylation of small molecules, peptides and proteins. The celares GmbH offers customized conjugation solutions on a fee for service basis. Services include the synthesis of tailor-made small molecules, activated reagents and polymers, process development for conjugation and purification, and the development of analytical methods for full characterization of bioconjugates. The celares GmbH has a clean room class D facility for the manufacturing of 0.5 to 5 kg of small molecules and activated intermediates, as well as for the preparation of conjugated drugs. A GMP certificate is issued by the local authorities. In addition, celares has developed proprietary platform technologies, namely celaSYS, celaSTAR, and PaSmax®. The latter technology is particularly useful for the development of next generation ADCs, based on payload solubilization and multiplexing. Clients are international biotech and pharma companies.

Am Klopferspitz 19 Planegg-Martinsried, 82152 GermanyChromoTek offers innovative research reagents based on Camelid-antibodies: Nano-Traps® and Nano-Boosters for highly efficient immunoprecipitation and super-resolution imaging of fluorescent fusion proteins, Chromobodies® for live-cell HCA and F2H® assay for real-time protein-protein interaction analysis.

Bonn, GermanyCTL offers products and services for immune assays. These include a library of cryopreserved human PBMC with HLA-typed donors that have established T cell reactivity. We specialize in immune characterization through ELISPOT, providing ImmunoSpot analyzers, ImmunoSpot kits, hands-on wetlab training, consultation, and GLP contract research.

17 Neuendorfstraße Hennigsdorf, BB, 16761 GermanyCentral BioHub eases the human biospecimen acquisition process by connecting biomedical researchers to biospecimen suppliers across the globe. Established in 2017 by a group of highly motivated scientific enthusiasts, Central BioHub continues as the leading biospecimen provider for research and development. Our zealous service is highly appreciated in the world of biomedical research. We have a long track of records and expertise in catering to the research needs of renowned pharmaceutical, biotech companies, academic institutions, and research organizations worldwide. Our inventory is vast, with millions of human biological materials sourced from different countries of the world. Our samples are well-defined, clinically annotated, and properly preserved to yield an accurate research endpoint. Quality service and customer satisfaction are paramount for us. Therefore, we handle every human biosample with ultimate precision and strict adherence to all safety standards and IRB protocols. With the growing market trust in our brand, we are proud to have the largest availability of standardized human biospecimens on our website. Valuing customer time and patience, we help to accelerate your biomedical innovation with our online human biospecimen marketplace. Researchers across the globe can order biosamples from any device directly from our website. The specially designed web filters on the website provide you with the required information about the biosamples and you can place orders with the ease of a click. Moreover, all orders are processed immediately with a secure logistics system for the fastest door-to-door delivery within 4-7 days. We value and understand our potential customer presence across the world Our services operate globally & allow us to accept orders from all countries.

Finkenweg 12 D 35325 Mücke GermanyClinicalworks offers management of clinical trials from study design to expert reporting.

Burscheider Str. 515 Leverkusen, D-51381 GermanyCOSMOlogic offers computational chemistry consulting services in application of QSAR studies, quantum chemistry, and ionic fluid screening.

Berlin, GermanyChemical-Pharmaceutical Laboratory provides API manufacturing, purity services, dissolution testing, pharmacopoeial analysis, purification, and characterization.

Am Seerain 13 D 74927 Eschelbronn GermanyCE-Immundiagnostika provides custom polyclonal antibodies.

Schierbusch 1 D-33161 Hövelhof GermanyC. Hedenkamp specializes in manufacturing supplementary food products.

21 Feodor-Lynen-Straße Hannover, NDS, 30625 GermanyCultex® Laboratories GmbH offers clients professional consultation and planning support in projects focusing on the identification and characterization of the effects of harmful substances with inhalational pathways by using tailored in vitro techniques. Taking a collaborative approach, we address solutions to test the cytotoxic and genotoxic potential of airborne substances under laboratory conditions as well as in environmental and work areas using exposure techniques at the air-liquid interface (ALI) and cells of the human respiratory tract.

5 Langeler Ring Troisdorf, NRW, 53842 GermanyCellSystems has been a reliable partner for the Life Science Community for 20 years now. We offer highly sophisticated research products, including EU validated 3D in vitro skin models for research and toxicology assays that were developed and are produced at our onsite laboratories. Additionally, CellSystems offers a wide array of contract services. CellSystems provides stem cell services, skin models, angiogenesis models, reagents, and cytokines.

CellSystems® Biotechnologie Vertrieb GmbH Hummelsbergerstr. 11 D - 53562 St. Katharinen GermanyCellSystems has been a reliable partner for the Life Science Community for 20 years now. We offer highly sophisticated research products, including EU validated 3D in vitro skin models for research and toxicology assays that were developed and are produced at our onsite laboratories. Additionally, CellSystems offers a wide array of contract services. CellSystems provides stem cell services, skin models, angiogenesis models, reagents, and cytokines.

7-9 Wallenroder Straße Berlin, Berlin, 13435 Germany

Alfred-Nobelstr. 10 Monheim, 40789 GermanyCube Biotech is a privately-held company based in Monheim, Germany, with a fully-owned subsidiary in Wayne, PA. Cube Biotech was founded in 2012 by a group of experts in membrane protein biology and organic chemistry. With more than 45 years of experience shared among us, we provide: Excellence in membrane protein expression, purification, stabilization, and crystallization Expertise in the synthesis of standard and tailor-made affinity matrices High-quality products at reasonable pricing We offer full-range or single packages of membrane protein services from cloning to structure determination and are building long-term partnerships with pharmaceutical, biotech, and academic organizations. We produce most of our service consumables at our facilities in Germany and sell these quality products at reasonable pricing. In addition, we have partnerships with renowned suppliers. Whatever you find on our website follows the principle: "we use what we sell, and we sell what we use"! Because we use our own products on a daily basis, we are constantly optimizing our products, services, and application protocols.

Monheim, GermanyCube Biotech is a privately-held company based in Monheim, Germany, with a fully-owned subsidiary in Wayne, PA. Cube Biotech was founded in 2012 by a group of experts in membrane protein biology and organic chemistry. With more than 45 years of experience shared among us, we provide: Excellence in membrane protein expression, purification, stabilization, and crystallization Expertise in the synthesis of standard and tailor-made affinity matrices High-quality products at reasonable pricing We offer full-range or single packages of membrane protein services from cloning to structure determination and are building long-term partnerships with pharmaceutical, biotech, and academic organizations. We produce most of our service consumables at our facilities in Germany and sell these quality products at reasonable pricing. In addition, we have partnerships with renowned suppliers. Whatever you find on our website follows the principle: "we use what we sell, and we sell what we use"! Because we use our own products on a daily basis, we are constantly optimizing our products, services, and application protocols.

Creative-Campus-Allee 12 Monheim am Rhein, NRW, 40789 GermanyCube Biotech is a privately-held company based in Monheim, Germany, with a fully-owned subsidiary in Wayne, PA. Cube Biotech was founded in 2012 by a group of experts in membrane protein biology and organic chemistry. With more than 45 years of experience shared among us, we provide: Excellence in membrane protein expression, purification, stabilization, and crystallization Expertise in the synthesis of standard and tailor-made affinity matrices High-quality products at reasonable pricing We offer full-range or single packages of membrane protein services from cloning to structure determination and are building long-term partnerships with pharmaceutical, biotech, and academic organizations. We produce most of our service consumables at our facilities in Germany and sell these quality products at reasonable pricing. In addition, we have partnerships with renowned suppliers. Whatever you find on our website follows the principle: "we use what we sell, and we sell what we use"! Because we use our own products on a daily basis, we are constantly optimizing our products, services, and application protocols.

Creative-Campus-Allee 12 Monheim am Rhein, NRW, 40789 GermanyCube Biotech is a privately-held company based in Monheim, Germany, with a fully-owned subsidiary in Wayne, PA. Cube Biotech was founded in 2012 by a group of experts in membrane protein biology and organic chemistry. With more than 45 years of experience shared among us, we provide: Excellence in membrane protein expression, purification, stabilization, and crystallization Expertise in the synthesis of standard and tailor-made affinity matrices High-quality products at reasonable pricing We offer full-range or single packages of membrane protein services from cloning to structure determination and are building long-term partnerships with pharmaceutical, biotech, and academic organizations. We produce most of our service consumables at our facilities in Germany and sell these quality products at reasonable pricing. In addition, we have partnerships with renowned suppliers. Whatever you find on our website follows the principle: "we use what we sell, and we sell what we use"! Because we use our own products on a daily basis, we are constantly optimizing our products, services, and application protocols.

Frankfurt, HE, 60528 GermanyCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

Am Klopferspitz 19a Martinsried, 82152 GermanyCRELUX provides collaborative drug discovery programs and specialized discovery services to pharma-, biotech- and chemical companies as well as academic and research institutes. This comprises high quality recombinant proteins (PRIME PROTEIN), protein crystallography services (XPRESS, XPEDITE and XPERT), as well as biophysical analysis and screening (INTRACT). In addition, Crelux_HitS provide FBDD and DEL screening services

Am Klopferspitz 19a 82152 Martinsried GermanyCRELUX provides collaborative drug discovery programs and specialized discovery services to pharma-, biotech- and chemical companies as well as academic and research institutes. This comprises high quality recombinant proteins (PRIME PROTEIN), protein crystallography services (XPRESS, XPEDITE and XPERT), as well as biophysical analysis and screening (INTRACT). In addition, Crelux_HitS provide FBDD and DEL screening services

Notkestr. 85 Building 48E EMBL User Office, Attn. (David Ruiz / Janis Müller CrystalsFirst) Hamburg, Hamburg, 22607 GermanyCrystalsFirst (CF) is an expert in scaling applications of X-ray crystallography that unlock chemical matter for challenging targets in drug discovery. The company’s proprietary technology SmartSoak® is utilized for stabilization of protein crystals and for design of high-performance soaking systems. The resulting systems are suited for small molecule soakings and crystal-based fragment screening campaigns for efficient hit identification.

Marbacher Weg 6 Marburg, Hessen, 35037 GermanyCrystalsFirst (CF) is an expert in scaling applications of X-ray crystallography that unlock chemical matter for challenging targets in drug discovery. The company’s proprietary technology SmartSoak® is utilized for stabilization of protein crystals and for design of high-performance soaking systems. The resulting systems are suited for small molecule soakings and crystal-based fragment screening campaigns for efficient hit identification.

Marbacher Weg 6 c/o Philipps-Universität Marburg Marburg, Hessen, 35037 GermanyCrystalsFirst (CF) is an expert in scaling applications of X-ray crystallography that unlock chemical matter for challenging targets in drug discovery. The company’s proprietary technology SmartSoak® is utilized for stabilization of protein crystals and for design of high-performance soaking systems. The resulting systems are suited for small molecule soakings and crystal-based fragment screening campaigns for efficient hit identification.

Annastraße 27 c/o Life Science Factory Göttingen, 37075 GermanyCrystalsFirst (CF) is an expert in scaling applications of X-ray crystallography that unlock chemical matter for challenging targets in drug discovery. The company’s proprietary technology SmartSoak® is utilized for stabilization of protein crystals and for design of high-performance soaking systems. The resulting systems are suited for small molecule soakings and crystal-based fragment screening campaigns for efficient hit identification.

Hans-Adolf-Krebs-Weg 9, Göttingen, 37077 GermanyFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Gottfried-Hagen-Strasse 20 Köln, 51105 GermanyFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Am Flughafen 12-14 Freiburgh Breisgau , 79108 GermanyFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Max-Planck-Strasse 15A Erkrath, 40699 GermanyFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Sandhofer Weg 7 Sulzfeld, Deutschland, D-97633 GermanyFor over 75 years, Charles River has provided essential products and services to help pharmaceutical and biotechnology companies, government agencies, and leading academic institutions around the globe, helping to accelerate their research and drug development efforts. With over 90 sites globally, we’re ready to tackle your product’s most unique challenges. Our focus on timeliness and accuracy in every stage of drug development means you can count on us to deliver reliable results – every step of the way. Visit our website to learn more about our portfolio and how we can support your research. www.criver.com

Schulberg 17 75175 PforzheimCIP Chemisches Institut Pforzheim GmbH is an independent, privately owned analytical laboratory. CIP arose from the fusion of two local laboratories in 2005. The services we offer include a wide range of physical, chemical, physical-chemical and microbiological analyses of different kind of samples, e.g. water, waste water and soil. In cooperation with our partners we offer a wide range of GLP studies associated with the approval of plant protection agents and chemicals. Over 30 years of experience and our comprehensive and efficient quality system (according to GLP and DIN EN ISO/IEC 17025) are the basis for various confirmations of competence, certifications, accreditations and notifications. Furthermore we act as partner in national internation R & D projects.

Kantstrasse 2 33790 Halle/Westfalen GermanyCentral Glass Germany is dedicated to process development, upscaling and production of active ingredients and intermediates for the pharmaceutical and cosmetics industry.

Bad Schmiedeberg, SA GermanyColep offers manufacturing for cosmetics, personal care, beauty, homecare and consumer healthcare products as well as a supplier of tinplate and plastic packaging.

Kemberger Straße 3 06905 Bad Schmiedeberg GermanyColep offers manufacturing for cosmetics, personal care, beauty, homecare and consumer healthcare products as well as a supplier of tinplate and plastic packaging.

Feldkirchen-Westerham, BY GermanyC.P.M. offers the production and packaging of ointments, creams and gels.

Frühlingstrasse 7 83620 Feldkirchen-Westerham GermanyC.P.M. offers the production and packaging of ointments, creams and gels.

Universitätsklinikum Würzburg and German Center for Heart Failure WürzburgThe goal of this project is the creation of an extensive biomaterials bank. Materials (blood, serum, plasma, DNA) from all patients who participate in studies in the network will be collected for this purpose. The objective is a consistently high quality standard for the processing, storage and management of all samples. The biomaterials bank is an investment in the future by the network. It enables the competence network and the research community in general to acquire new scientific knowledge about the development, progression and prognosis of the different forms of heart failure.

Andernach, GermanyClinical Research Services Andernach offers spectrometry, ELISAs, and pharmacodynamic models.

Poststr. 3 Dortmund, NRW, 44137 Germanysynthesis labs, production, analytics

1 Im Mühlenbruch Königswinter, NRW, 53639 GermanyA health-economics and value-based healthcare consultancy focused on medical devices, medical technologies, diagnostics and pharmaceuticals. Coreva Scientific can help you turn your product data into market value. We specialize in de novo model development, value dossier creation, meta-analysis, and real-world data collection tools.

10 Heerweg Tübingen, BW, 72070 GermanyIn our modern laboratory, we offer chromatographic analyses as a service to our customers, specializing particularly in the analyses of peptides, amino acid derivatives and other chiral substances: • Determination of enantiomeric purity of amino acids and amino acid derivatives • Reliable determination of enantiomeric purity of peptides via GC-MS • Most efficient amino acid analysis via enantiomer labelling • Determination of traces of amino acids as contaminants • Sequencing of peptides and elucidation of by-products via LC-MSn • Determination of Molecular weight and Identification of Side Products • Determination of identity, content and purity by HPLC • Analyses for product control of fine chemicals o water content o solvent residues o acetate and trifluoro acetate determination (via GC or IC) o anions (via IC) Substance-specific validation can be performed to verify that no matrix effects falsify/influence the results.

An Der Bahn 5 Norderstedt, 22844 GermanyTHE NEW GENERATION FOR LIVE CELL SHIPMENTS Cellbox - a fully conditioned portable CO2 incubator for the transport of biological material under laboratory conditions. Cellbox Solutions is a young technology company developing and marketing innovative logistics solutions for the BioMedTech, Pharmaceutical and Academic sectors.

Paul-Ehrlich-Str. 23 D-72076 Tübingen, BW, 72076 GermanyCeMeT GmbH is a service provider for metagenomic analysis.

Andresenstraße 1a Bitterfeld-Wolfen, 06766 GermanyChiroBlock offers custom R&D on - and the synthesis of - new compounds on scales < 100 kg. This includes chemical reagents, building blocks, reference standards, and impurities. With our three business lines: - MoleculeFactory - ReDesignFactory - SupplyChainFactory we address all needs regarding customer specific, exclusive compounds: - the first time / one time synthesis of entirely new molecules - the development / optimisation, entire "re-design" of synthesis routes and - the QM regulated regular supply of intermediates / special chemicals for the customer's supply chain. The main advantages of ChiroBlock's services are the innovative contract options that cover regulations for ChiroBlock to cover all chemical risks even for R&D related projects.

1 Andresenstraße Bitterfeld-Wolfen, SA, 06766 GermanyChiroBlock offers custom R&D on - and the synthesis of - new compounds on scales < 100 kg. This includes chemical reagents, building blocks, reference standards, and impurities. With our three business lines: - MoleculeFactory - ReDesignFactory - SupplyChainFactory we address all needs regarding customer specific, exclusive compounds: - the first time / one time synthesis of entirely new molecules - the development / optimisation, entire "re-design" of synthesis routes and - the QM regulated regular supply of intermediates / special chemicals for the customer's supply chain. The main advantages of ChiroBlock's services are the innovative contract options that cover regulations for ChiroBlock to cover all chemical risks even for R&D related projects.

Adalbert-Zoellner-Str. 1 Marktredwitz, Bavaria, 95615 GermanyCfm Oskar Tropitzsch GmbH assists the chemical, pharmaceutical and biotechnological industry in sourcing and producing chemical specialties. The core of our work is to supply the product which our customer is looking for - with the right documentation, the correct quantity from mg to mt and proper quality and this not only for a one shot business but to support projects from RnD state up to commercial production. To achieve these challenging goals Cfm Oskar Tropitzsch GmbH uses its excellent knowhow and worldwide network of qualified suppliers.

Altenhöferallee 3 FIZ Frankfurt, Hessen, 60438 GermanyWe want to speed up your drug discovery project by quickly and accurately characterizing your small molecule inhibitor in living cells using the NanoBRET technology. Let’s illuminate science together!

Frankfurt Innovation Center (FIZ) Altenhöferallee 3 Frankfurt, Hessen, 60438 GermanyWe want to speed up your drug discovery project by quickly and accurately characterizing your small molecule inhibitor in living cells using the NanoBRET technology. Let’s illuminate science together!

Ganghoferstraße 47 Maisach, Gernlinden, D-82216 GermanyWe have over 50 years of experience making high performance release agents, die lubricants, tire paints, purge compounds and ancillary products related to molding, casting and forming operations. Our expertise goes well beyond just the products that we develop and manufacture, it reaches into the production processes of the industries that we serve. Our seasoned professionals help our customers to produce higher quality parts, more efficiently and at lower overall cost.

Engesserstr. 4b Freiburg im Breisgau 79108 GermanyChemCon offers analytical services, chromatography, manufacturing, custom synthesis, microbiological testing, process development, and scale up.

Justus-von-Liebig-Strasse 14 Eppelheim, 69214 GermanyCLS Cell Lines Service offers cell lines, stem cells, and contamination assay products and services.

Trakehner Str. 3 Frankfurt a.M. 60487 GermanyChemetall offers lithium, cesium, organometallic chemistry, special metals, and metal sulfides for chemical processes.

Luckenwalde, BB GermanyChiracon specializes and supplies chiral building blocks, raw materials, and intermediates for API production and development.

Stieffring 14 Berlin, 13627 GermanyCPL SACHSE offers API production, chemical development, analytical development, stability testing, regulatory, and project management services.

Otto-von-Guericke-Straße 1 53757 Sankt Augustin / Bonn GermanyDolorgiet offers production of pharmaceutical drugs in therapeutic area with specialty in areas of stomach / intestines, rheumatism / pain, CNS and in the OTC sector.

Werner-von-Siemens Str. 3 D-93128 Regenstauf / Germany

Weißensberg, BY, 88138 GermanyCandor Bioscience offers assay development, quality management, biomarker analysis, and media.

Weissensberg, GermanyCandor Bioscience offers assay development, quality management, biomarker analysis, and media.

Tübingen, BW GermanyCeCo Labs specializes in bacterial cell walls and offers cell wall fragment products, isolation, and analysis services.

Waldhäuser Straße 70/8 Tübingen, 72076 GermanyCeCo Labs specializes in bacterial cell walls and offers cell wall fragment products, isolation, and analysis services.

CLS Cell Lines Service GmbH Dr. Eckener-Strasse 8 69214 Eppelheim Germany

Paul-Ehrlich-Straße 23 Tübingen, 72076 GermanyCeGaT, Center for Genomics and Transcriptomics, is a service provider for DNA and RNA sequencing of humans, animals, plants, and microorganisms.

4 Sauerbruchweg Sauerbruchweg 4 Berlin, Berlin, 10117 GermanyCharité Research Organisation is a Contract Research Organisation focused on helping its clients move development projects from First Time In Human to Proof of Concept as quickly and efficiently as possible. Based in Berlin, at the very heart of Europe, CRO was founded in collaboration with Charité - Universitätsmedizin Berlin. Charité Research Organisation: 1. is a Qualified Phase I and POC unit with 70+ beds for hospitalisation and large out-patient facilities; 2. has approximately 200 dedicated staff, including board certified physicians, nurses, lab technicians, pharmacists, PMs, QMs, data entry staff, independent QA and own recruitment team; 3. conducted more than 367 First Time in Human, Phase 1 and POC projects since 2006 in the therapy areas of rheumatology, dermatology, gastroenterology, endocrinology, pulmonology, cardiology, neurology, psychiatry, infectious diseases and ophthalmology; 4. is specialised for the study types of First Time in Human, Phase 1 and POC, which Includes biosimilar studies, imaging, medical device and methodology studies, blood and tissue sampling studies, pre-screening studies; 5. provides a unique environment with access to accredited safety lab, ISO certified biomarker labs, imaging facilities and licensed GMP pharmacy, key opinion leaders from the Charité University Hospital and relevant patient populations.

Charitéplatz 1 - 10117 Berlin (Mitte) - GermanyCharité Research Organisation is a Contract Research Organisation focused on helping its clients move development projects from First Time In Human to Proof of Concept as quickly and efficiently as possible. Based in Berlin, at the very heart of Europe, CRO was founded in collaboration with Charité - Universitätsmedizin Berlin. Charité Research Organisation: 1. is a Qualified Phase I and POC unit with 70+ beds for hospitalisation and large out-patient facilities; 2. has approximately 200 dedicated staff, including board certified physicians, nurses, lab technicians, pharmacists, PMs, QMs, data entry staff, independent QA and own recruitment team; 3. conducted more than 367 First Time in Human, Phase 1 and POC projects since 2006 in the therapy areas of rheumatology, dermatology, gastroenterology, endocrinology, pulmonology, cardiology, neurology, psychiatry, infectious diseases and ophthalmology; 4. is specialised for the study types of First Time in Human, Phase 1 and POC, which Includes biosimilar studies, imaging, medical device and methodology studies, blood and tissue sampling studies, pre-screening studies; 5. provides a unique environment with access to accredited safety lab, ISO certified biomarker labs, imaging facilities and licensed GMP pharmacy, key opinion leaders from the Charité University Hospital and relevant patient populations.

Karl-Heinz-Beckurts-Straße 13 Jülich, 52428 Germany, EuropeCelonic provides production of biologics, scale up, cultivation, assays, toxicity testing, and cell line development.

Juelich, GermanyCelonic provides production of biologics, scale up, cultivation, assays, toxicity testing, and cell line development.

Sand 14 Tübingen, 72070 GermanyComputomics offers bioinformatics services to support genomics, transcriptomics, genome variant discovery, and epigenetic variance.

Kanzlerstr. 4 Düsseldorf, NRW, 40472 GermanyConstructure is an engineering and scientific consulting firm with headquarters in Ratingen, Germany, serving clients in the medical, pharmaceutical and industrial construction field. Services include product certification and regulatory consulting, product testing, engineering design and R&D support, as well as inspection, failure analysis, decomissioning and recalls.

Balcke-Duerr-Allee 1 Ratingen, NRW, 40882 GermanyConstructure is an engineering and scientific consulting firm with headquarters in Ratingen, Germany, serving clients in the medical, pharmaceutical and industrial construction field. Services include product certification and regulatory consulting, product testing, engineering design and R&D support, as well as inspection, failure analysis, decomissioning and recalls.

Balcke-Duerr-Allee 1 Ratingen, 40882 GermanyConstructure is an engineering and scientific consulting firm with headquarters in Ratingen, Germany, serving clients in the medical, pharmaceutical and industrial construction field. Services include product certification and regulatory consulting, product testing, engineering design and R&D support, as well as inspection, failure analysis, decomissioning and recalls.

Brandstuecken 23 Hamburg, 22549 GermanyConstructure is an engineering and scientific consulting firm with headquarters in Ratingen, Germany, serving clients in the medical, pharmaceutical and industrial construction field. Services include product certification and regulatory consulting, product testing, engineering design and R&D support, as well as inspection, failure analysis, decomissioning and recalls.

Robert-Rössle-Str. 10 Bldg. 79 Berlin, 13125 GermanyCELLphenomics GmbH is a state-of-the-art in vitro service provider aimed at offering high-quality, reasonable priced cell culture models complementing classical in vivo assays using patient-derived 3D cell cultures. We view ourselves as partners with our customers, our employees, our scientific community and our environment. Our mission is to help the biotech and pharma industries create innovative testings of novel anti-cancer drugs. We are committed to help oncologists and their patients make informed choices to improve quality of lives. We aim to become a recognized brand name in the field of preclinical testing, capitalizing on the sustained interest in alternatives to animal testing.

Cellbricks GmbH c/o Bayer CoLaborator (S141) Müllerstr.178 Berlin, Brandenburg, 13353 GermanyCellbricks is a 3D Bioprinting company based in Berlin. Our mission is to replicate human tissue at scale so that researchers and doctors can provide patients with better treatments and clinical outcomes. Our vision is a future where the biofabrication of organs and human tissue is common medical practice so humans can enjoy longer and healthier lives, and where the sophistication of in vitro models accurately recapitulates native tissues and systems.

Gustav-Meyer-Allee 25 Berlin, Brandenburg, 13355 GermanyCellbricks is a 3D Bioprinting company based in Berlin. Our mission is to replicate human tissue at scale so that researchers and doctors can provide patients with better treatments and clinical outcomes. Our vision is a future where the biofabrication of organs and human tissue is common medical practice so humans can enjoy longer and healthier lives, and where the sophistication of in vitro models accurately recapitulates native tissues and systems.

c/o CoLaborator (S141) Muellerstrasse 178 Berlin, 13353 GermanyCellbricks is a 3D Bioprinting company based in Berlin. Our mission is to replicate human tissue at scale so that researchers and doctors can provide patients with better treatments and clinical outcomes. Our vision is a future where the biofabrication of organs and human tissue is common medical practice so humans can enjoy longer and healthier lives, and where the sophistication of in vitro models accurately recapitulates native tissues and systems.

Otto-Hahn-Strasse, Plankstadt, 68723 GermanyCordenPharma is an expert Contract Manufacturing partner helping leading pharmaceutical and biotechnology companies link their requirements for product success with their patients’ healthier lives. Formed as a pharmaceutical branch of International Chemical Investors Group in 2006, CordenPharma provides specialised technologies that are ideal for the development and manufacturing of oral, sterile, highly potent and antibiotic pharmaceutical Drug Products, their Active Pharmaceutical Ingredients, and associated Global Supply Chain and Packaging Services. Full-Service CMO for a Global Market As a full-Service CMO we are committed to bringing inspired global service and flexible solutions spanning the entire pharmaceutical product continuum. Your pharmaceutical development projects will benefit from a legacy of expertise through our: Big Pharma / Biotech calibre facilities with stringent quality systems and standards Proven track record of success in small and large-scale API and Drug Product cGMP Contract manufacturing and Development Network of global cGMP manufacturing facilities with combined capabilities and successful track record of inspections by all relevant Health Authorities Dedicated project managers supported by a project team to ensure consistent coordination, communication and alignment of progress throughout all project phases With multiple cGMP compliant facilities across Europe and the United States, CordenPharma is the flexible, efficient, and cost-effective solution for all of your contract manufacturing needs.

Weimar, Thuringia GermanyCentic Biotec offers synthesis services for genes, oligonucleotides, siRNA, peptides, and custom antibodies.

Moskauer Straße 67 Weimar, D-99427 GermanyCentic Biotec offers synthesis services for genes, oligonucleotides, siRNA, peptides, and custom antibodies.

Repräsentanz Lilienweg 28 Wessling, Munich D - 82234 GermanyCONFARMA offers physicochemical tests, microbiological, hygiene related, galenical and biological/toxicological investigations and consulting services.

Fontanestr. 84-90 15366 Neuenhagen GermanyCooperative Clinical Drug Research and Development (CCDRD) offers toxicokinetic and pharmacokinetic analysis, bioanalysis, and clinical trial services.

Remscheid, NRW GermanyChemCollect offers custom synthesis and lead optimization.

Westen 44 D-42855 Remscheid, GermanyChemCollect offers custom synthesis and lead optimization.

Rüppurrer Str 92 Karlsruhe, D-76137 GermanyChemPur provides over 3500 metals and compounds, inorganic specialty chemicals, elements, nano-powder, and over 65,000 organic intermediates.

Gartenweg 14 Wandlitz OT Basdorf, Berlin D-16348 GermanyConsulting in Drug Design offers QSAR services.

60 Gottlieb-Keim-Straße Bayreuth, BY, 95448 GermanyCytox leads biosafety testing of medical devices, cosmetics, textiles, paints and consumer products through. Since 2001, we serve customers with regard to the toxicological questions about your products. All tests are based on the standard series for determining the biocompatibility according to ISO and ASTM and to REACH requirements performed.

Schillingallee 68 Rostock, 18057 GermanyCentogene is a worldwide leader in the field of genetic diagnostic testing for rare hereditary diseases, with a broad test portfolio covering over genes, biochemical tests, biomarker and clinical whole exome sequencing and whole genome sequencing. Centogene’s mission is to support medical professionals with in-depth medical expertise to diagnose early and safe the reason for the patients’ burden. Analyzing samples from all over the world allows Centogene to constantly expand its unique portfolio resulting in the largest systematic documentation of the genetic results, named CentoMD®. This mutation database integrates genetic and clinical information, enabling the highest quality, knowledge-based genetic testing and biomarker development. In addition to offering diagnostic services for individual patients, Centogene is a pivotal partner to some of the most respected names in the industry.

Meyerhofstrasse 1 Heidelberg, 69117 GermanyCellzome's in house drug discovery focuses on epigenetic and signal transduction (kinase) drug targets in inflammation and cancer, but it can also be applied in other disease indications.

Pirk, BY, 92712 GermanyConstantia Hueck Foils specializing in packaging food, processed meat, pharma products, and labeling.

Pirkmühle 14-16 D-92712 Pirk GermanyConstantia Hueck Foils specializing in packaging food, processed meat, pharma products, and labeling.

Hertzstrasse 7 D-50859 Cologne, GermanyCato Research provides clinical trials, regulatory services, pharmacovigilance, CMC, and quality assurance.

Staufenstrasse 4 60323 Frankfurt am Main, GermanyCato Research provides clinical trials, regulatory services, pharmacovigilance, CMC, and quality assurance.

Joachim-Jungius-Str. 9 18059 Rostock GermanyCytocentrics AG provides cutting-edge solutions to assist drug screening of ion channel targets, especially in early drug profiling and safety pharmacology

Fraunhoferstr. 18 b Martinsried, 82152 GermanyCoriolis is a globally operating service provider and one of the world leaders in formulation research and development of (bio)pharmaceutical drugs and vaccines. As a family-owned and independent company with an interdisciplinary team of highly skilled scientists and an expert scientific advisory board, we provide cutting-edge services and tailor-made solutions for our customers. Founded in 2008, Coriolis is the expert in the development of liquid formulations,development of formulation and process for freeze-dried products, as well as analytical services including GMP (Good Manufacturing Practice) and release analysis. We have supported the successful development of many drug products and our scientists are eager to apply their experience on a large range of molecules (including proteins, peptides, monoclonal antibodies, RNA/DNA carrier systems, virus-like particles, viruses, bacteria and vaccines) to your project.

Rigaer Str. 1 Bremen, 28217 GermanyChimera Biotec - your GLP-certifed CRO for excellence in immunoassay development, validation and bioanalysis since 2000. Your study needs define our assays! We tailor your customized assay to your study or use already available kits. Our laboratory is GLP-certified and offers immunoassay services under the regulation of your choice (GLP/GCP/exploratory) with compliance to FDA, EMA and ICH. We provide ultra sensitive sample testing for all phases of drug development - from discovery to preclinical and clinical studies. Applications: - Biomarker - PK/PD - ADA/Immunogenicity - nAb assays Available Plattforms: - Immuno-PCR (Imperacer®) - Simoa® (Quanterix) - MSD™ (Meso Scale Discovery) - ELISA Send us a request today!

Emil-Figge-Strasse 76A Dortmund, 44227 GermanyChimera Biotec - your GLP-certifed CRO for excellence in immunoassay development, validation and bioanalysis since 2000. Your study needs define our assays! We tailor your customized assay to your study or use already available kits. Our laboratory is GLP-certified and offers immunoassay services under the regulation of your choice (GLP/GCP/exploratory) with compliance to FDA, EMA and ICH. We provide ultra sensitive sample testing for all phases of drug development - from discovery to preclinical and clinical studies. Applications: - Biomarker - PK/PD - ADA/Immunogenicity - nAb assays Available Plattforms: - Immuno-PCR (Imperacer®) - Simoa® (Quanterix) - MSD™ (Meso Scale Discovery) - ELISA Send us a request today!

Mascheroder Weg 1b 38124 Braunschweig GermanyDSMZ provides identification services, cell lines, virus testing, electron microscopy, serology, chemotaxonomy, and ribotyping.

Marktplatz 5 31840 Hessisch Oldendorf GermanyDreluso Pharmazeutika offers manufacturing of herbal and homeopathic remedies, medical devices, food supplements, dietetic foods and spirits.

61 Brunnenstraße Alfter, NRW, 53347 GermanyDerma Consult GmbH, founded in 1990, is an independent contract research organization specialized in the dermatological testing of cosmetics, cosmetic ingredients, toiletries and pharmaceuticals. The range of services includes product safety and efficacy determination using a wide range of bioengineering methods. For a listing please consult the services page.

Handwerkstrasse 15 70565 StuttgartDEKRA Assurance Services is an entity of DEKRA SE. Since it was founded 90 years ago, DEKRA has been a pioneer in matters of safety. Building on this basis, we have ushered in a new phase of company development with our strategic program "Vision 2025" and we have set ourselves an ambitious goal to be achieved by 2025: we will be the global partner for a safe world. With this ambition, we are combining innovative services that make a contribution to sustainability in business and in society. Together with leading institutions, research facilities and corporate partners, we are working on solutions for current and future challenges. Our social responsibility is not limited to our services which offer greater safety to our customers, but also includes our employees, suppliers and other stakeholders, too. The topics of occupational safety and human rights are afforded a high degree of attention here. In the environmental domain, our services play an instrumental part in protecting the environment and conserving resources. We also take advantage of this expertise internally, such as in 2015 when we further enhanced the organizational structure of our environmental management. Centrally managed efficiency-boosting measures are enabling us to cut costs and at the same time make a sustainable contribution to the environment.

Handwerkstrasse 15 Stuttgart, 70565 GermanyDEKRA Assurance Services is an entity of DEKRA SE. Since it was founded 90 years ago, DEKRA has been a pioneer in matters of safety. Building on this basis, we have ushered in a new phase of company development with our strategic program "Vision 2025" and we have set ourselves an ambitious goal to be achieved by 2025: we will be the global partner for a safe world. With this ambition, we are combining innovative services that make a contribution to sustainability in business and in society. Together with leading institutions, research facilities and corporate partners, we are working on solutions for current and future challenges. Our social responsibility is not limited to our services which offer greater safety to our customers, but also includes our employees, suppliers and other stakeholders, too. The topics of occupational safety and human rights are afforded a high degree of attention here. In the environmental domain, our services play an instrumental part in protecting the environment and conserving resources. We also take advantage of this expertise internally, such as in 2015 when we further enhanced the organizational structure of our environmental management. Centrally managed efficiency-boosting measures are enabling us to cut costs and at the same time make a sustainable contribution to the environment.

Marie-Curie-Str. 7 Goettingen, 37079 GermanyDeveloGen offers in vivo and in vitro pharmacology services including assay development, target identification, target validation, high throughput screening, and animal models for efficacy studies.

45 Ave François Clément MONDORF, 5612 Luxembourg

Tatzberg 47 Dresden, Saxony, 01307 GermanydenovoMATRIX designs and produces biomaterials which enable cell manufacturing in higher quality, quantity and safety.

Tatzberg 47 Dresden, Saxony, 01307 GermanydenovoMATRIX designs and produces biomaterials which enable cell manufacturing in higher quality, quantity and safety.

St. Petersburger Str. 2 Dresden, 01069 GermanyFounded in 1997 and based in Dresden, Germany, the DKMS Life Science Lab became part of the DKMS Group in 2001. As the world’s leading HLA typing laboratory, our lab carries out typing according to the latest scientific standards and has achieved numerous milestones. We always strive to develop new and innovative processes. With the adaption of the NGS (Next Generation Sequencing) method, for example, we have been able to increase the number of processed samples to well over one million per year! At the same time, this has significantly reduced the typing costs per sample.

Sample Receipt - Clinical Laboratory St. Petersburger Str. 2 Dresden, 01069 GermanyFounded in 1997 and based in Dresden, Germany, the DKMS Life Science Lab became part of the DKMS Group in 2001. As the world’s leading HLA typing laboratory, our lab carries out typing according to the latest scientific standards and has achieved numerous milestones. We always strive to develop new and innovative processes. With the adaption of the NGS (Next Generation Sequencing) method, for example, we have been able to increase the number of processed samples to well over one million per year! At the same time, this has significantly reduced the typing costs per sample.

Probeneingang/ Sample Receipt St. Petersburger Str. 2 Dresden, 01069 GermanyFounded in 1997 and based in Dresden, Germany, the DKMS Life Science Lab became part of the DKMS Group in 2001. As the world’s leading HLA typing laboratory, our lab carries out typing according to the latest scientific standards and has achieved numerous milestones. We always strive to develop new and innovative processes. With the adaption of the NGS (Next Generation Sequencing) method, for example, we have been able to increase the number of processed samples to well over one million per year! At the same time, this has significantly reduced the typing costs per sample.

Sample Receipt - HD Laboratory St. Petersburger Str. 2 Dresden, 01069 GermanyFounded in 1997 and based in Dresden, Germany, the DKMS Life Science Lab became part of the DKMS Group in 2001. As the world’s leading HLA typing laboratory, our lab carries out typing according to the latest scientific standards and has achieved numerous milestones. We always strive to develop new and innovative processes. With the adaption of the NGS (Next Generation Sequencing) method, for example, we have been able to increase the number of processed samples to well over one million per year! At the same time, this has significantly reduced the typing costs per sample.

Riedstraße Darmstadt, HE, 64295 GermanyDöhler offers quality assurance services. These include analyses of your products in our laboratories and specialist advice from our technical field service, always giving you an independent perspective in all issues relating to quality assurance in production.

Oskar-von-Miller-Straße 10 D-86956 Oberbayern, GermanyDartsch Scientific provides contract research, pharmacological screening, and biocompatibility testing.

Warburgstr. 45 Hamburg, 20354 GermanyDianova supplies antibodies, immnoassays, and other products for molecular biology.

Hamburg, HH GermanyDianova supplies antibodies, immnoassays, and other products for molecular biology.

PO Box D-96045 Bamberg GermanyDr. R. Pfleger offers manufacturing of ointments, suppositories, tablets and granules.

DLD Diagnostika GmbH Adlerhorst 15 Hamburg D-22459 GermanyDLD Diagnostika provides in-vitro diagnosis.

Hamburg, HH GermanyDLD Diagnostika provides in-vitro diagnosis.

44 Alfred-Herrhausen-Straße Witten, NRW, 58455 GermanySince 1990 DermaTronnier has been working as an independent institute in the field of experimental dermatology at the University Witten/Herdecke. We examine influences on human skin using state-of-the-art testing devices and methods. The great demands we place on our scientific work apply to both basic and contract research.

Wethouder Beversstraat 185 Enschede, 7543 BK NetherlandsGMP XRPD and SAXS Characterization of Pharmaceuticals. DANNALAB is an independent CRO that specializes in physico-chemical studies of pharmaceuticals. Our core expertise relates to X-Ray Powder Diffraction (XRPD) and Small Angle X-Ray Scattering (SAXS). At DANNALAB we use XRPD to identify the polymorphic type and crystallinity of an active pharmaceutical ingredient (API) in its pure form, as well as in formulation or dosage forms. We support our customers during research, pre-formulation and formulation stages. Among our services, we offer GMP method development and validation for identification and quantification. The methods we offer are developed according to USP <941>, Ph.Eur. <2.9.33> and ICH guidelines. For quality control during the batch release we offer affordable cGMP XRPD with a turnaround time of 3 to 6 days. Our facility and procedures are compliant with the cGMP quality system. We use SAXS to study internal structure of drug delivery systems - such as lyposomes and nanoparticulates. We also use SAXS to study the higher-order structure of biologics, their aggregation pathways, and their stability patterns. To ensure effective and safe intellectual property management, we offer a range of services related to pharmaceutical patents.

Winzerlaer Str. 2 Jena, Thuringia, 07745 GermanyDynamic42 GmbH has developed human, three-dimensional physiological organ models in a biochip. We are a contract research organization and we are testing new drugs as well as novel dosage forms of drugs (i.e. nanoparticles). In addition, we are developing customized biochip-based assays and organ models (disease and infection models) for further studies.

BIOPARC 850 Boulevard Sébastien Brant ILLKIRCH-STRASBOURG FranceDomain Therapeutics NA (DTNA) Inc. specializes in G Protein-Coupled Receptor (GPCR) and Receptor Tyrosine Kinase (RTK) signaling and function. Our BRET-based bioSensAllTM biosensor technology allows for detailed and broad-spectrum signaling profiling of GPCRs, RTKs and their ligands, while leaving these receptors untagged. This technology revolves primarily around the real-time monitoring of receptor proximal events immediately linked to the transmembrane receptor activity, namely heterotrimeric G protein activation and β-arrestin coupling for the GPCRs, and SH2-domain proteins for the RTKs. The GPCR assay brings the unique capacity to quantify the engagement of 14 distinct heterotrimeric G protein subtypes as well as both non-visual β-arrestin isoforms. The RTK assay gives the possibility to follow the recruitment of various SH2-domain proteins and study the complete trafficking of these receptors. Both assays provide a complete and detailed fingerprint of any GPCR / RTK ligand and allow to study the impact of receptor mutations on their signaling. This data is particularly valuable in a screen / early drug development program to select and optimally design your lead compound. Domain Therapeutics applies a multi-string corporate strategy to grow its business through: validation of its technologies through collaborative partnerships with Pharma/Biotechs, generation of an internal pipeline of 1st in class drug candidates for high unmet needs in CNS and oncology, valuation of its preclinical assets through spin-out vehicles, financed by leading investment funds or supported by development-only companies.

Bgm.-Schlosser-Str. 6 A Augsburg, 86199 GermanyDr. Ehrenstorfer offers high purity analytical standards used as reference materials in residue analysis and environmental analysis such as pesticides, metabolites, PAH, PBB, PCB, and explosives

Augsburg, BY GermanyDr. Ehrenstorfer offers high purity analytical standards used as reference materials in residue analysis and environmental analysis such as pesticides, metabolites, PAH, PBB, PCB, and explosives

GermanyThe current initiative suggests to establish the " Danubian Biobank foundation for public utility in molecular medicine of aging disorders " that networks and expands all biobanking activities and the core scientific competences of the Danubian universities, teaching hospitals and rehabilitation clinics between Ulm and Budapest and of associated collaborating regional centers in the field of non-cancer aging disorders. In this context we will address 1. vascular disease (e.g. stroke, myocardial infarction, peripheral artery disease, arterial thrombosis, kidney failure), 2. metabolic disease (e.g. obesity, metabolic syndrome), and 3. neurodegenerative disorders (e.g. dementia, parkinsonism).

Munzinger Straße 5a D - 79111 Freiburg GermanyOur objective is to support our customers in the pharmaceutical industry in their efforts to develop effective and safe products by providing biostatistical and data management services of the highest quality. We are committed to giving both the society and our customers careful, reliable and competent management of clinical data, scientifically correct and accepted analysis, and comprehensive and concise reporting of the results from clinical studies. We aim to achieve this objective in working together with qualified people in a stimulating, open and cooperative environment, promoting the professional and personal development of our employees, and offering attractive, safe and healthy workplaces.

37 Engelstraße Münster, NRW, 48143 GermanyResults you can rely on – by a team that takes a personal interest in your success. ‘Taking your success personally’ – a statement to which we are committed. In our opinion, the dermatological expertise that you will find in abundance at Dermatest is by itself not enough to satisfy your needs. We do not simply want to do our job well; we want our work to lead to measurable results for you, our clients. This goal is firmly rooted in our personal commitment – something you cannot fail to notice when you work with us.

187 Klever Straße Goch, NRW, 47574 GermanyDFE Pharma specializes in manufacturing excipients.

Lise Meitner Strasse 2 D-24145 Kiel–Wellsee GermanyDemeditec Diagnostics GmbH is your expert for diagnostic laboratory products in routine and research

Inhoffenstraße 7B 38124 Braunschweig GERMANY

Germaniastrasse 7 Kassel, 34119 GermanyAsk us about our cell and gene therapy products, including both research and clinical use Discovery Leukopaks. Discovery Life Sciences are the Biospecimen & Biomarker Specialists™. We have the world’s largest biospecimen inventory and procurement network with preeminent multi-omic service laboratories to accelerate precision medicine programs in oncology, immuno-oncology, immunology, inflammation, infectious diseases, and beyond. We are pleased to announce ReachBio is now a part of Discovery Life Sciences. Our biobanks include more than 10 million biospecimens and we have hundreds of clinical sites (Discovery Partners®) that allow researchers to build bespoke study cohorts and seamlessly interrogate them using our CLIA certified, GLP-compliant service laboratories, including our world-renowned Genomic Sequencing and bioinformatics laboratory, HudsonAlpha Discovery, our expert IHC services laboratory that developed the pembrolizumab PD-L1 IHC companion diagnostic prototype, our Proteomic Services labs that offer Olink, Luminex, Seer Proteograph and Mass Spec protein profiling, and our Cell Biology laboratory providing extensive Flow cytometry and single cell RNASeq services with GMP-compliant leukapheresis products for cell therapy development and manufacturing. We are committed to quality and integrity with ISO 13485, GMP- and GCLP-compliant and CLIA-certified labs, stringent IRB and Ethics Committee compliance, and all required approvals and certifications. Navigating US and international personal data protection, drug development and diagnostic development regulations is one of our core competencies.

Wippertstr. 2 Freiburg, 79100 GermanyDallmann Consultancy specializes in monoclonal antibodies,a nd immunogenicity risk assessment and offers consulting services to support regulatory and development strategy.

Eichendorffstrasse 37 60320 Frankfurt am Main GermanyDeutsche Lanolin Gesellschaft is entirely specialised in trading with lanolin and its derivatives.

Nattermannallee 1 D - 50829 Köln (Cologne) GermanyDirevo provides tailor-made, biology- based solutions for partners in several sectors of the biomass conversion industry.

Cologne, NRW GermanyDirevo provides tailor-made, biology- based solutions for partners in several sectors of the biomass conversion industry.

Bötzinger Strasse 29 B 79111 Freiburg GermanyDiarect provides custom proteins, gene design, bacterial expression, purification, stabilization products, and immunoassay substrates.

Perchtinger Straße 8/10 München, 81379 GermanyDynamic Biosensors is a provider of instruments, consumables, and services in the field of analytical systems for the characterization of biomolecules and molecular interactions. Our headquarter is located in Martinsried south of Munich, a vital center of Europe‘s biotechnology industry. Dynamic Biosensors commercializes switchSENSE® technology, a groundbreaking platform technology for the analysis of biomolecules with applications in R&D and drug development.

Lochhamerstr. 15 Martinsried, 82152 GermanyDynamic Biosensors is a provider of instruments, consumables, and services in the field of analytical systems for the characterization of biomolecules and molecular interactions. Our headquarter is located in Martinsried south of Munich, a vital center of Europe‘s biotechnology industry. Dynamic Biosensors commercializes switchSENSE® technology, a groundbreaking platform technology for the analysis of biomolecules with applications in R&D and drug development.

Ernsbergerstr. 5a 81241 Munich, GermanyDojindo Molecular Technologies offers assay kits and reagents for cell analysis, Mitochondrial research, Autophagy, protein analysis, oxidative stress detection, and surface modification studies.

1A Erna-Scheffler-Straße Köln, NRW, 51103 GermanyDr. Notghi Contract Research GmbH is a service provider for large, medium and small-sized companies in the pharmaceutical, generics and biotechnology industries. We support and advise you in the conduct and management of national and international projects. The company was founded in 1999 by Dr. Arman Notghi, has its headquarters in Berlin and since 01.08.2015 a second location in Cologne. Dr. Notghi Contract Research GmbH has enjoyed continuous and stable growth thanks to the confidence placed in us by our longstanding customers and the dedication of our employees. We are a competent and reliable partner for both large and small organizations with projects or studies of all levels of complexity. With over 90 specialized employees available across Europe for our clients, we are able to cover a wide range of fields in clinical research. After 10 years, Dr. Notghi Contract Research GmbH can proudly look back on more than 300 clinical research studies and projects that were successfully accomplished. This is a solid foundation from which the company intends to develop into the future. We are there when our clients need us whatever the circumstances. Make use of the expertise, experience and flexibility we offer you.

Venloer Str. 47-5350672 Cologne, GermanyDr. Oestreich + Partner provides software solutions, data capture, biometrics, and product safety.

Alfredstrasse 98 D-45131 Essen GermanyDiagenics provides in vitro diagnostics and marketing for their cardiology, neurology, and gynecology products and research.

Roentgenstrasse 3 Regensburg, D-93055 GermanyDavids Biotechnologie offers antibody production and purification, cell based assays, and peptide synthesis services.

8 Lilly-Reich-Straße Hildesheim, NDS, 31137 GermanyA small and flexible team of highly qualified specialists, we are expert in various fields of the plant protection and biocide sector. Our company has been operating successfully since 1995, skillfully communicating with authorities and laboratories. With wide ranging, flexible, cost-effective and highly targeted services DHD-Consulting GmbH will help you in specific questions or through the whole procedure for speedy and efficient registration of your product. We provide a comprehensive regulatory affairs management for your company, satisfying all your registration needs.

Dynamostr. 19 68165 Mannheim GermanyWe have been an independent service provider for the chemical and pharmaceutical industries since 1996, with currently over 400 employees at sites within the EU, Asia and the USA. The outstanding technical qualification of our experts and their international language competence serves as a guarantee for our deep understanding of your products. In addition to German and English, they speak many other European languages, as well as Arabic, Chinese, Japanese and Thai.

Im Neuenheimer Feld 280 D-69120 HeidelbergDKFZ German Cancer Research Center provides antibody, proteomic, genomic, and sequencing services.

Hahnstrasse 70, 60528 Frankfurt, GermanyEcron Acunova offers bioanalytical testing, pharmcokinetic and pharmacodynamic screening, LCMS/MS, and HPLC services.

Kleine Präsidentenstr. 1 10178 BerlinEpigenomics offers DNA methylation, biomarker, and molecular diagnostic services.

Berlin, Berlin GermanyEpigenomics offers DNA methylation, biomarker, and molecular diagnostic services.

6C Im Mediapark Köln, NRW, 50670 GermanyEastHORN Clinical Services is one of the leading CROs in Europe. EastHORN offers phase I-IV clinical research services specialized in rescue studies. Our services also include regulatory affairs, medical writing, pharmacovigilance, and data management.

1 Meyerhofstraße Heidelberg, BW, 69117 GermanyThe Advanced Light Microscopy Facility (ALMF) offers a collection of state-of-the-art light microscopy equipment and image processing tools.

Anzinger Str. 7a Ebersberg, D-85560 GermanyEurofins Medigenomix offers genotyping, DNA/RNA extraction, biomarker analysis, pharmacogenomics, and expression analysis services.

Nürnberger Strasse 12 90537 FEUCHT GermanyExcella manufactures products for Home Care & Industrial, Cosmetics, Pharmaceuticals and Food.

Feucht, BY GermanyExcella manufactures products for Home Care & Industrial, Cosmetics, Pharmaceuticals and Food.

Inselwiesenstraße 10 c/o Mrs. Melanie Melcher-Mourgas Heilbronn, 74076 GermanyEvidentic offers original EU manufactured and licensed drugs, repackaged as research consumables. These clinical-grade molecules and therapeutic antibodies can be used for R&D and for early drug development projects. As a sourcing specialist and licensed pharmaceutical wholesaler, we source medicines from drug manufacturers, repackage the original drugs into commonly used laboratory test tubes. Now, scientists and drug developers can purchase original clinical-grade molecules more easily. Biosimilar developers have another advantage: they can get different batches of the same original drug, which isn't usually available simultaneously on the market. Our business model allows access to these biological molecules in a simple, easy, and cost-effective manner when compared with the purchase of entire vials.

Raffaelstraße 4 D-30177 Hannover, GermanyEBRC is a privately-owned consulting organisation based in Hannover, Germany, providing consulting services with a focus on chemical, biocidal and agrochemical industries. Specialised scientific experience is available in all key discisplines relevant for product safety with respect to human health and environment. Task force management and coordination of industry consortia is another important aspect of our work.

Industriepark Höchst Gebäude D610 Frankfurt, Hessen, 65926 GermanyEUROAPI delivers as CDMO small molecules APIs, Oligonucleotides & Peptides and Ionizable Lipids for LNPs for R&D, clinical phases and commercial batches. Our TIDES & small molecule platform in Frankfurt is responsible for small non-GMP batches in R&D projects and doing process development and analytical development from small scale to large GMP batches supporting clinical phases 1/2/3. We also do chemical conjugations like GalNac, peptides, PEG, sugars, or small molecules.

Industriepark Höchst Gebäude D610 Frankfurt, Hessen, 65926 GermanyEUROAPI delivers as CDMO small molecules APIs, Oligonucleotides & Peptides and Ionizable Lipids for LNPs for R&D, clinical phases and commercial batches. Our TIDES & small molecule platform in Frankfurt is responsible for small non-GMP batches in R&D projects and doing process development and analytical development from small scale to large GMP batches supporting clinical phases 1/2/3. We also do chemical conjugations like GalNac, peptides, PEG, sugars, or small molecules.

Robert-Rössle-Str. 10 D-13125 BerlinFounded in 1993 with a strong focus in organic synthesis, biomolecular modification and purification, emp BIOTECH provides quality reagents and services for the life science community. We manufacture fine chemicals, DNA synthesis reagents, tools for molecular biology, chromatography media and related products. In addition, we provide contract organic synthesis, protein and nucleic acid labeling, peptide synthesis, consulting and analytical services. Furthermore, we have an ongoing interest in the fields of non-radioactive detection systems, synthetic organic and polymer chemistries and purification services. Our novel detection platforms combine non-enzymatic chemiluminescence signal amplification and fluorescence enhancement strategies, both supported by synthetic innovations.

Robert-Rössle-Str. 10 Berlin, D-13125 United StatesFounded in 1993 with a strong focus in organic synthesis, biomolecular modification and purification, emp BIOTECH provides quality reagents and services for the life science community. We manufacture fine chemicals, DNA synthesis reagents, tools for molecular biology, chromatography media and related products. In addition, we provide contract organic synthesis, protein and nucleic acid labeling, peptide synthesis, consulting and analytical services. Furthermore, we have an ongoing interest in the fields of non-radioactive detection systems, synthetic organic and polymer chemistries and purification services. Our novel detection platforms combine non-enzymatic chemiluminescence signal amplification and fluorescence enhancement strategies, both supported by synthetic innovations.

Experimentelle & Diagnostische Immunologie Aspenhaustrasse 25 D-72770 Reutlingen GermanyExperimental & Diagnostic Immunology provides cell biology, cell culture systems, immunoassays, test models, and immunology.

Reutlingen, BW GermanyExperimental & Diagnostic Immunology provides cell biology, cell culture systems, immunoassays, test models, and immunology.

Industrie Center Obernburg D - 63784 Obernburg

Lichtenbergstraße 8 Garching bei München, 85748 GermanyeADMET develops and markets innovative IT solutions for the prediction of important properties of chemicals and drugs, especially physical and ("drug-like") characteristics.

Garching, BY, 85748 GermanyeADMET develops and markets innovative IT solutions for the prediction of important properties of chemicals and drugs, especially physical and ("drug-like") characteristics.

European ScreeningPort GmbH Schnackenburgallee 114 D-22525 HamburgEuropean ScreeningPort (ESP) is a public-private partnership that offers small molecule screening services.

Alfred-Nobel-Str. 10 40789 Monheim am Rheinevoxx technologies is an industrial biotech company focusing on the development and production of industrial enzymes and development of oligosaccharides and polysaccharides to be primarily used in food applications. We are specifically targeting ingredients that offer consumer health benefits. evoxx has a team of about 40 scientists and technicians and two sites in Germany, Monheim am Rhein and Potsdam. Monheim am Rhein The Monheim site is the headquarters of former evocatal GmbH, which was founded in 2006 by Dr. Thorsten Eggert and two Professors as a spin-off of the Institute for Molecular Enzyme Technology at the University of Düsseldorf in the Forschungszentrum Jülich (Research Center Jülich). Since then, the company has been active in scientific networks, headed international collaboration projects and has built a solid business in the development, production and sales of enzymes. evocatal was one of the founding members of Germany’s Industrial Association of White Biotechnology (IWBio), Cluster Industrial Biotechnology (CLIB2021) and supports Cluster CleanTech NRW. Potsdam The industrial biotech company aevotis GmbH, located on the Biotech Campus Hermannswerder in Potsdam, Germany was founded in 2009 by Martina Döring and Dr. Volker Landschütze. The founding shareholders held management positions in Bayer BioScience GmbH Potsdam and have more than 25 years hands-on experience in business development and R&D in the field of biotechnology. Both founders are well versed in the management of complex, global and cross-industry projects and over the years, have built up a global network of contacts in science and industry. The company is developing innovative, proprietary carbohydrate products for application in down-stream industries based a technology and patent portfolio exclusively licensed in from Bayer.

Alfred-Nobel-Str. 10 Monheim am Rhein, 40789 Germanyevoxx technologies is an industrial biotech company focusing on the development and production of industrial enzymes and development of oligosaccharides and polysaccharides to be primarily used in food applications. We are specifically targeting ingredients that offer consumer health benefits. evoxx has a team of about 40 scientists and technicians and two sites in Germany, Monheim am Rhein and Potsdam. Monheim am Rhein The Monheim site is the headquarters of former evocatal GmbH, which was founded in 2006 by Dr. Thorsten Eggert and two Professors as a spin-off of the Institute for Molecular Enzyme Technology at the University of Düsseldorf in the Forschungszentrum Jülich (Research Center Jülich). Since then, the company has been active in scientific networks, headed international collaboration projects and has built a solid business in the development, production and sales of enzymes. evocatal was one of the founding members of Germany’s Industrial Association of White Biotechnology (IWBio), Cluster Industrial Biotechnology (CLIB2021) and supports Cluster CleanTech NRW. Potsdam The industrial biotech company aevotis GmbH, located on the Biotech Campus Hermannswerder in Potsdam, Germany was founded in 2009 by Martina Döring and Dr. Volker Landschütze. The founding shareholders held management positions in Bayer BioScience GmbH Potsdam and have more than 25 years hands-on experience in business development and R&D in the field of biotechnology. Both founders are well versed in the management of complex, global and cross-industry projects and over the years, have built up a global network of contacts in science and industry. The company is developing innovative, proprietary carbohydrate products for application in down-stream industries based a technology and patent portfolio exclusively licensed in from Bayer.

1 Zum Grauen Stein Wiesbaden, HE, 65201 GermanyScientific Consultant - Experienced Bioinformatician synthesizes knowledge from experiments, big data mining, computation and experience Quickly identify needs and their solutions Deliver reliable, high quality bioinformatics from basic data handling to most sophisticated mining & visualization. Implement efficient computational and experimental pipelines to get a job done Help wet-labs improve processes, quality and turnaround Provide preclinical and clinical statistics support Manage projects, studies, collaborations and resources Deliver toward goals and ensure knowledge transfer Respond quickly and allow maximal flexibility Understand biopharma discovery & development Combine in-depth technology expertise with therapeutic area knowledge

Hambierich 34 Saterland, Niedersachsen, 26683 GermanyesqLABS is a consulting firm and research organization that offers software and biosimulation solutions to aid decision-making in the life sciences industry. At esqLABS we specialize in developing advanced simulation models for the pharmaceutical, chemical, crop and healthcare industries. Our PBK and multi-scale organism-level QSP models are designed to predict the effects of chemicals and biologics on different populations and species, supporting research and development by assessing pharmacokinetics, efficacy, and safety. We pride ourselves on our commitment to integrity and excellence in everything we do. We also offer custom-tailored, open-source solutions and actively contribute to the open systems pharmacology community through our involvement in the software development for the OSP Suite (www.open-systems-pharmacology.org with PK-Sim and MoBi and R tools), ensuring that our approach is always transparent, flexible, and open.

Altensteinstrasse 40 Berlin, Berlin, 14195 GermanyExazyme provides AI services for speeding up protein engineering by an order of magnitude

Oespeler Kirchweg 10 Dortmund, Deutschland, 44379 GermanyEcocyte provides xenopus oocytes, heterologous expression, and in vitro electrophysiology.

Industriepark Höchst, G837 Frankfurt am Main, 65926 GermanyThe main activities of the Company include: •Organic synthesis of Screening Compounds, Building Blocks, and Fragments •R&D services (custom synthesis, compound library design, hit follow-up support, and lead optimization) to support the research programs conducted by pharmaceutical and biotech companies, drug discovery centers, academic institutions and other research organizations worldwide.

Im Stadtwald, Geb. A1 Saarbrücken, 66123 GermanyElexoPharm offers medicinal chemistry in support of hit identification, hit to lead, and lead optimization services.

Saarbrücken, SL GermanyElexoPharm offers medicinal chemistry in support of hit identification, hit to lead, and lead optimization services.

Allerheiligenstraße 12 77728 Oppenau GermanyEtol offers manufacturing of both pharmaceutical and cosmetic products as well as medical devices.

Oppenau, BW GermanyEtol offers manufacturing of both pharmaceutical and cosmetic products as well as medical devices.

Idar-Oberstein, RP GermanyEufets provides assay development, analytical services, non-clinical studies, manufacturing, retroviral vector stocks, immunohistochemistry, and biological services.

Attilastraße 5a Donaustauf, 93093 GermanyESy-Labs as an innovative start up is specialised in Electrifying Synthesis for the production of organic fine and specialty chemicals as well as inorganic resources with a reduced amount of chemicals up to 90%. Founded in August 2018 by Prof. Waldvogel (CTO) and Dr. Gärtner (CEO), the company connects the production of renewable energy and chemical conversion. Based on that, ESy-Labs offers consulting, custom electrosynthesis and process development, which is supported by a design of experiment (DoE) concept for process optimisation and scale up, to provide the technology electrosynthesis tailored to suit a market need and cost-efficient for customers. Therefore, ESy-Labs can provide electrosyntheses from the g-scale to the low ton-scale per year, being supplemented by integrated biotechnological and chemical catalytic process steps. Additionally, ESy-Labs offers metabolite synthesis via oxidative electrosynthesis for studies of APIs.

An der Irler Höhe 3a Regensburg, 93055 GermanyESy-Labs as an innovative start up is specialised in Electrifying Synthesis for the production of organic fine and specialty chemicals as well as inorganic resources with a reduced amount of chemicals up to 90%. Founded in August 2018 by Prof. Waldvogel (CTO) and Dr. Gärtner (CEO), the company connects the production of renewable energy and chemical conversion. Based on that, ESy-Labs offers consulting, custom electrosynthesis and process development, which is supported by a design of experiment (DoE) concept for process optimisation and scale up, to provide the technology electrosynthesis tailored to suit a market need and cost-efficient for customers. Therefore, ESy-Labs can provide electrosyntheses from the g-scale to the low ton-scale per year, being supplemented by integrated biotechnological and chemical catalytic process steps. Additionally, ESy-Labs offers metabolite synthesis via oxidative electrosynthesis for studies of APIs.

Siemensstraße 7 Regensburg, 93055 GermanyESy-Labs as an innovative start up is specialised in Electrifying Synthesis for the production of organic fine and specialty chemicals as well as inorganic resources with a reduced amount of chemicals up to 90%. Founded in August 2018 by Prof. Waldvogel (CTO) and Dr. Gärtner (CEO), the company connects the production of renewable energy and chemical conversion. Based on that, ESy-Labs offers consulting, custom electrosynthesis and process development, which is supported by a design of experiment (DoE) concept for process optimisation and scale up, to provide the technology electrosynthesis tailored to suit a market need and cost-efficient for customers. Therefore, ESy-Labs can provide electrosyntheses from the g-scale to the low ton-scale per year, being supplemented by integrated biotechnological and chemical catalytic process steps. Additionally, ESy-Labs offers metabolite synthesis via oxidative electrosynthesis for studies of APIs.

Helmholtzstrasse 22 Science Park I D-89081 Ulm, GermanyEurofins EAG Materials Science, LLC has a long history, dating back to the birth of the company in 1978 in California, as Charles Evans & Associates. Over the years we have expanded from a single location offering SIMS only to having over 200 employees offering over 30 different services via 14 locations in 8 different countries. The original focus of the company was supporting semiconductor manufacturing but now we also work with multiple further industries beyond semiconductors, including: solar/PV, lighting, photonics, energy storage, aerospace & defense, medical devices, raw materials, glass, polymers and plastics and consumer products. EAG's analytical expertise is what enables us to help our clients to meet their goals. Our on-demand analytical testing services can help streamline R&D, solve urgent problems during manufacturing and help resolve materials related issues in the global supply chain, both within and between organizations.

Essen, GermanyEvonik provides custom synthesis and chemicals for a wide variety of fields.

Essen, NRW GermanyEvonik provides custom synthesis and chemicals for a wide variety of fields.

Mendelstraße 17 Münster, NRW, 48149 GermanyA pioneer in functional phenomics, evorion biotechnologies offers a proprietary multiparametric platform to characterize thousands of cell-cell interactions at single-cell resolution. Current single-cell multi-omics technologies are an invaluable tool for biological research and precision medicine but fail to directly link a single cell's multi-omics data to changes in its functional phenotype over time. This is where our innovative chip-based technology excels. For the first time, researchers can simultaneously analyze multiple phenotypes (cellular functions, intracellular protein expression, surface, and secreted protein profiles) and the cellular interactions of thousands of cellular interactions in a highly parallelized manner. They can then couple those insights directly to each cell’s underlying genetic and transcriptional makeup, merging functional phenotypes with multi-omics data. Our technologies and services are designed to comprehensively analyze biological systems over time and space, and at the resolution of the smallest unit of life. We aim to improve human health by answering unresolved questions with high-end tools and services that reveal novel single-cell mechanistic insights in the field of cell-based therapies, oncology, infectious disease, immunology, and regenerative medicine. Partnering with academia and industry, we enable the research breakthroughs today that will translate to the therapies of tomorrow.

Meyerhofstraße 1 Heidelberg 69117 GermanyEuropean Molecular Biology Laboratory (EMBL) provides protein production, spectrometry, microarrays, microscopes, genomics, and bioinformatics.

Frankfurt Biotechnology Innovation Centre, Altenhoeferallee 3 Frankfurt am Main, D 60438 GermanyErgomed provides clinical consulting, regulatory affairs, data management, and disease expertise.

Gottfried-Hagen-Strasse 20 Köln, 51105 GermanyFAST. We produce and analyse DNA & RNA. Eurofins Genomics is part of the Eurofins Group, with facilities in Europe, the USA and Asia. We are an internationally leading provider of DNA sequencing services, genotyping services, DNA synthesis products and bioinformatics services. COMPLETE. We support you from research to application. With our assistance, you will master any challenge along your value chain. We combine outstanding expertise with state-of-the-art instruments, methods and technologies. We support standard and challenging research projects, as well as complex strategies for large interdisciplinary companies. RELIABLE. We work with academics, pharma, food, diagnostics, agriculture and biotechnology. Our highly automated and lean-optimised lab processes allow us to deliver highly-reliable results. This is documented by the ISO 17025 and ISO 13485 accreditation, as well as the GLP, GCP and cGMP certifications. Reach for the stars. We are glad to assist you!

c/o Julia Bottlang Jakob-Stadler-Platz 7 Constance, 78467 GermanyFAST. We produce and analyse DNA & RNA. Eurofins Genomics is part of the Eurofins Group, with facilities in Europe, the USA and Asia. We are an internationally leading provider of DNA sequencing services, genotyping services, DNA synthesis products and bioinformatics services. COMPLETE. We support you from research to application. With our assistance, you will master any challenge along your value chain. We combine outstanding expertise with state-of-the-art instruments, methods and technologies. We support standard and challenging research projects, as well as complex strategies for large interdisciplinary companies. RELIABLE. We work with academics, pharma, food, diagnostics, agriculture and biotechnology. Our highly automated and lean-optimised lab processes allow us to deliver highly-reliable results. This is documented by the ISO 17025 and ISO 13485 accreditation, as well as the GLP, GCP and cGMP certifications. Reach for the stars. We are glad to assist you!

Jakob-Stadler-Platz 7 Konstanz, 78467 GermanyFAST. We produce and analyse DNA & RNA. Eurofins Genomics is part of the Eurofins Group, with facilities in Europe, the USA and Asia. We are an internationally leading provider of DNA sequencing services, genotyping services, DNA synthesis products and bioinformatics services. COMPLETE. We support you from research to application. With our assistance, you will master any challenge along your value chain. We combine outstanding expertise with state-of-the-art instruments, methods and technologies. We support standard and challenging research projects, as well as complex strategies for large interdisciplinary companies. RELIABLE. We work with academics, pharma, food, diagnostics, agriculture and biotechnology. Our highly automated and lean-optimised lab processes allow us to deliver highly-reliable results. This is documented by the ISO 17025 and ISO 13485 accreditation, as well as the GLP, GCP and cGMP certifications. Reach for the stars. We are glad to assist you!

Anzinger Str. 7a Ebersberg, 85560 GermanyFAST. We produce and analyse DNA & RNA. Eurofins Genomics is part of the Eurofins Group, with facilities in Europe, the USA and Asia. We are an internationally leading provider of DNA sequencing services, genotyping services, DNA synthesis products and bioinformatics services. COMPLETE. We support you from research to application. With our assistance, you will master any challenge along your value chain. We combine outstanding expertise with state-of-the-art instruments, methods and technologies. We support standard and challenging research projects, as well as complex strategies for large interdisciplinary companies. RELIABLE. We work with academics, pharma, food, diagnostics, agriculture and biotechnology. Our highly automated and lean-optimised lab processes allow us to deliver highly-reliable results. This is documented by the ISO 17025 and ISO 13485 accreditation, as well as the GLP, GCP and cGMP certifications. Reach for the stars. We are glad to assist you!

Behringstrasse 6 / 8 Planegg, 82152 GermanyWith more than 30 years of experience and thousands of GMP/GLP studies per year Eurofins BioPharma Product Testing Munich GmbH supports its clients especially in the fields of toxicology, bioassays, microbiology, biocompatibility, immunoanalytical and bioanalytical studies. We cover the whole range from standardized test to special requirements and tailor-made studies. We are certified in accordance with GLP (Good Laboratory Practice) and GMP (Good Manufacturing Practice) and have been accredited with DIN EN ISO 17025 for the testing of medical devices. We are listed by the World Health Organization (WHO) and have been audited successfully by the FDA. In addition our preferred partner BSL BIOSERVICE in Munich received full accreditation by AAALAC (Association for the Assessment and Accreditation of Laboratory Animal Care).

Robert-Koch-Str. 3A - Haus 2 Planegg, 82152 GermanyWith more than 30 years of experience and thousands of GMP/GLP studies per year Eurofins BioPharma Product Testing Munich GmbH supports its clients especially in the fields of toxicology, bioassays, microbiology, biocompatibility, immunoanalytical and bioanalytical studies. We cover the whole range from standardized test to special requirements and tailor-made studies. We are certified in accordance with GLP (Good Laboratory Practice) and GMP (Good Manufacturing Practice) and have been accredited with DIN EN ISO 17025 for the testing of medical devices. We are listed by the World Health Organization (WHO) and have been audited successfully by the FDA. In addition our preferred partner BSL BIOSERVICE in Munich received full accreditation by AAALAC (Association for the Assessment and Accreditation of Laboratory Animal Care).

6 Behringstraße Planegg, BY, 82152 GermanyWith more than 30 years of experience and thousands of GMP/GLP studies per year Eurofins BioPharma Product Testing Munich GmbH supports its clients especially in the fields of toxicology, bioassays, microbiology, biocompatibility, immunoanalytical and bioanalytical studies. We cover the whole range from standardized test to special requirements and tailor-made studies. We are certified in accordance with GLP (Good Laboratory Practice) and GMP (Good Manufacturing Practice) and have been accredited with DIN EN ISO 17025 for the testing of medical devices. We are listed by the World Health Organization (WHO) and have been audited successfully by the FDA. In addition our preferred partner BSL BIOSERVICE in Munich received full accreditation by AAALAC (Association for the Assessment and Accreditation of Laboratory Animal Care).

10 Bruktererstraße Bottrop, NRW, 46238 GermanyEurosweet 's main line of business is the production and processing of raw materials as well as trade with products for the food industry.

Paul-Thomas-Strasse 56, 40599 Düsseldorf, GermanyThomas Emery (Snr) started a tallow and candle business in 1840. A decade later, The Emery Candle Company offered customers sturdier, whiter, dripless candles made of stearic acid. Soon, the expanded product line also included elaine oil (oleic acid) and sweetwater (glycerine). By 1872, the company was involved in fatty acid exploration while growing an existing product line that included elaine oil (oleic acid) and sweetwater (glycerine). Click here to find more. Today, 174 years later, Emery Oleochemicals is a name synonymous with the production of high quality, natural-based chemicals commonly made from natural oils and fats. Our business is increasingly focused in high-value derivatives. Through our six dedicated business units , we have the ability to provide you with customisable, high-performance, market-based solutions. Backed by an extensive distribution network covering over 50 countries globally, Emery Oleochemicals applies its philosophy, Creating Value with our wide-ranging product portfolio for use in the home and personal care, construction, automotive, lubricants, packaging, food and beverage, pharmaceuticals, textiles, electrical and electronics, furniture and bedding, and agriculture industries. Headquartered in Shah Alam, Malaysia,our manufacturing facilities and sales and marketing offices are located in Asia Pacific, Europe and North America. We are backed by a diverse workforce of more than 1,000 people and an extensive distribution network covering over 50 countries globally.

Helmut-Neynaber Str.49, 27612 Loxstedt, GermanyThomas Emery (Snr) started a tallow and candle business in 1840. A decade later, The Emery Candle Company offered customers sturdier, whiter, dripless candles made of stearic acid. Soon, the expanded product line also included elaine oil (oleic acid) and sweetwater (glycerine). By 1872, the company was involved in fatty acid exploration while growing an existing product line that included elaine oil (oleic acid) and sweetwater (glycerine). Click here to find more. Today, 174 years later, Emery Oleochemicals is a name synonymous with the production of high quality, natural-based chemicals commonly made from natural oils and fats. Our business is increasingly focused in high-value derivatives. Through our six dedicated business units , we have the ability to provide you with customisable, high-performance, market-based solutions. Backed by an extensive distribution network covering over 50 countries globally, Emery Oleochemicals applies its philosophy, Creating Value with our wide-ranging product portfolio for use in the home and personal care, construction, automotive, lubricants, packaging, food and beverage, pharmaceuticals, textiles, electrical and electronics, furniture and bedding, and agriculture industries. Headquartered in Shah Alam, Malaysia,our manufacturing facilities and sales and marketing offices are located in Asia Pacific, Europe and North America. We are backed by a diverse workforce of more than 1,000 people and an extensive distribution network covering over 50 countries globally.

Lübeck, SH GermanyEUROIMMUN provides reagents for medical laboratory diagnostics including test systems, antibodies, and ELISA services.

Seekamp 31 Lübeck, D-23560 GermanyEUROIMMUN provides reagents for medical laboratory diagnostics including test systems, antibodies, and ELISA services.

Parc d'innovation Pole API, 300 bld Sébastien Brant 67412 Illkirch cedex FranceEpiGex is dedicated to serving the life science community by providing innovative tools for proteomics and epigenetics. EpiGex holds an innovative technology named Epigenome DiscoveryTM, which allows to efficiently decipher complex protein interaction networks. Our company is also committed to the continual development of innovative solutions for epigenetic applications. EpiGex offers a wide range of services, including cell line constructs, customized antibody and peptide synthesis. Epigex gathers people that have more than 20 years experience in molecular biology and biochemistry. Our company is located in the Alsace region with a unique concentration of international life sciences & healthcare players.

49A Walther-Rathenau-Straße Greifswald, MV, 17489 GermanyThe focus of Enzymicals is to provide integrated solutions for biocatalytic applications. Dedicated to design, develop and implement cost-effective, sustainable and scalable chemo-biocatalytic routes. Enzymicals offers a recognized expertise in the application of enzymatic processes for the synthesis of complex chemicals up to industrial scale.

Rudower Chaussee 29 Berlin, 12489 GermanyCount different immune cell types in archived specimens with PCR. Use our products to count immune cells in samples for which flow cytometry cannot be used. E.g. dried blood, archived/frozen blood, PBMC, buffy coat, tissue, or liquor. Epimune is an ISO 13485 certified molecular diagnostic company that develops and commercializes tests for immune cell quantification.

Robert-Rössle-Str. 10 Erwin-Negelein-Haus (D79) Berlin, 13125 Germanyengine protein arrays are a powerful tool for high throughput and multiplexed protein analysis. Explore thousands of protein interactions in one step! - investigate highly complex autoantibody profiles - discover biomarkers for disease diagnosis, therapy monitoring, etc. - determine antibody specificity and cross-reactivity - perform epitope mapping of antibodies - identify protein-protein interactions for analysis of metabolic or regulatory pathways engine Protein Array Service - Your Question. Our Service. Your Result! We support you in biomarker discovery and the determination of antibody specificity. 1. Send us 50 µl sample (e.g. serum, CSF, cell supernatant)! 2. We analyze in house e.g. • auto-antibody profiles • protein interactions • disease-related protein modifications like citrullination, phosphorylation, carbamylation 3. Receive your evaluated results • Analysis of interactions • Antigen identification • Scientific report • Raw data • Including technical discussion 4. Identify your recognized antigens directly!

Neuendorfstraße 17 Hennigsdorf, 16761 Germanyengine protein arrays are a powerful tool for high throughput and multiplexed protein analysis. Explore thousands of protein interactions in one step! - investigate highly complex autoantibody profiles - discover biomarkers for disease diagnosis, therapy monitoring, etc. - determine antibody specificity and cross-reactivity - perform epitope mapping of antibodies - identify protein-protein interactions for analysis of metabolic or regulatory pathways engine Protein Array Service - Your Question. Our Service. Your Result! We support you in biomarker discovery and the determination of antibody specificity. 1. Send us 50 µl sample (e.g. serum, CSF, cell supernatant)! 2. We analyze in house e.g. • auto-antibody profiles • protein interactions • disease-related protein modifications like citrullination, phosphorylation, carbamylation 3. Receive your evaluated results • Analysis of interactions • Antigen identification • Scientific report • Raw data • Including technical discussion 4. Identify your recognized antigens directly!

Boxbergring 107 Heidelberg, 69126 GermanyEMBLEM, established in 1999, identifies, protects and commercializes the intellectual property developed in the EMBL world, from EMBL alumni and from non-EMBL third parties. EMBLEM currently manages a portfolio of more than 400 granted patents and patent applications, and, over term, has created more than 25 spin-out companies. EMBLEM facilitates and accelerates the transfer of innovative technology from basic research to industry by working closely with industrial partners spanning the biotech, IT and mechanical/electrical engineering markets and currently has more than 400 licensees of EMBL technologies. For more information, please visit https://www.embl-em.de

Notkestrasse 85, Building 15 CSSB (c/o DESY) Hamburg, Hamburg, 22607 GermanyEMBLEM, established in 1999, identifies, protects and commercializes the intellectual property developed in the EMBL world, from EMBL alumni and from non-EMBL third parties. EMBLEM currently manages a portfolio of more than 400 granted patents and patent applications, and, over term, has created more than 25 spin-out companies. EMBLEM facilitates and accelerates the transfer of innovative technology from basic research to industry by working closely with industrial partners spanning the biotech, IT and mechanical/electrical engineering markets and currently has more than 400 licensees of EMBL technologies. For more information, please visit https://www.embl-em.de

Robert-Rössle-Str. 10 13125 Berlin-Buch, GermanyBased on more than 25 years of experience, EPO is providing customized oncology and immuno-oncology services for the preclinical development of novel anti-cancer drugs. Our portfolio includes more than 600 well characterized patient derived xenograft (PDX) models as well as a broad variety of cell-line derived xenografts (CDX) for studies in immuno-deficient, syngeneic or humanized mouse strains. EPO is offering services such as in vivo imaging for our orthotopic and metastasis models, flow cytometry and experimental pathology services including autopsy, histopathology and immunohistochemistry. Our team of highly trained scientists is offering advice for optimized study designs to ensure the best possible outcome for our clients.

Barkhausenweg 1 22339 Hamburg GermanyEppendorf provides laboratory supplies, such as pipettes, centrifuges, and microcentrifuge tubes.

Walsrode, GermanyThe ERA Consulting Group provides biopharmaceutical consulting relating to quality, nonclinical, and clinical aspects.

65439 Flörsheim am Main, DeutschlandECT Oekotoxikologie GmbH is a privately owned enterprise that was founded in 1993. In compliance with Good Laboratory Practice (GLP), we perform standardised ecotoxicological tests in the laboratory as well as at semi-field and field level. Established test systems cover the aquatic (pelagic and benthic) and terrestrial environment and also include dung organisms. In addition to performing standardised tests, we modify existing or develop new methods to improve the characterisation of environmental risks caused by chemicals and contaminated matrices such as waste. This activity has in many cases contributed to the establishment of new international guidelines. The results of our experimental and desk-based studies are used in the environmental risk assessment of industrial chemicals, biocides, pharmaceuticals, plant protection products, wastes and genetically modified organisms. Through constant involvement in (inter-) national research projects and cooperation with universities, ECT keeps up with the state of the art in the field of ecotoxicology. Based on broad scientific expertise we develop strategies to solve problems that may arise during marketing authorisation, notification or classification of chemical substances. Since 1993, ECT has been growing constantly and employs currently about 30 permanent staff. All staff members hold a degree from a university or a technical (high) school. In addition, we host each year several undergraduate and graduate students, who often conduct their thesis work with us. Our laboratory and office space covers now more than 1500 m² and includes an isotope laboratory.

Meyerhofstr. 1, 69117 Heidelberg, GermanyThe Advanced Light Microscopy Facility (ALMF) offers a collection of state-of-the-art light microscopy equipment and image processing tools. The facility was set up as a cooperation between EMBL and industry to improve communication between users and producers of high-end microscopy technology. The ALMF supports in-house scientists and visitors in using light microscopy methods for their research. The ALMF also regularly organises in-house and international courses to teach basic and advanced light microscopy methods. Major projects and accomplishments The ALMF currently manages 20 advanced microscope systems and 10 high-content microscopes from leading industrial companies. Several workstations for image analysis are provided. More than 50 visitors per year come to carry out their own experiments in the ALMF or to evaluate microscopy equipment. The ALMF was the seed for the European Light Microscopy Initiative (ELMI) that establishes links between core facilities, users and industry throughout Europe. A number of Proof-of-Concept studies have been hosted in the framework of Eurobioimaging. 5 genome wide screens were supported by the ALMF. Usage of the facility has exceeded 50,000 hours per year. Services provided Project planning, sample preparation, microscope selection and use, image processing and visualization. Support of advanced microscopy techniques e.g. FRAP, FRET, FCS, laser nanosurgery and super-resolution. Developing accessory software and microscopy equipment, co-developments with industrial partners, pre-evaluation of commercial equipment. Supporting all aspects of automated microscopy and high-throughput microscopy projects, including RNAi technology. Image and data analysis for light microscopy

Meyerhofstr. 1 Heidelberg, 69117 GermanyThe Advanced Light Microscopy Facility (ALMF) offers a collection of state-of-the-art light microscopy equipment and image processing tools. The facility was set up as a cooperation between EMBL and industry to improve communication between users and producers of high-end microscopy technology. The ALMF supports in-house scientists and visitors in using light microscopy methods for their research. The ALMF also regularly organises in-house and international courses to teach basic and advanced light microscopy methods. Major projects and accomplishments The ALMF currently manages 20 advanced microscope systems and 10 high-content microscopes from leading industrial companies. Several workstations for image analysis are provided. More than 50 visitors per year come to carry out their own experiments in the ALMF or to evaluate microscopy equipment. The ALMF was the seed for the European Light Microscopy Initiative (ELMI) that establishes links between core facilities, users and industry throughout Europe. A number of Proof-of-Concept studies have been hosted in the framework of Eurobioimaging. 5 genome wide screens were supported by the ALMF. Usage of the facility has exceeded 50,000 hours per year. Services provided Project planning, sample preparation, microscope selection and use, image processing and visualization. Support of advanced microscopy techniques e.g. FRAP, FRET, FCS, laser nanosurgery and super-resolution. Developing accessory software and microscopy equipment, co-developments with industrial partners, pre-evaluation of commercial equipment. Supporting all aspects of automated microscopy and high-throughput microscopy projects, including RNAi technology. Image and data analysis for light microscopy

Robert-Rössle-Str. 10 13125 Berlin - GermanyCompound analysis supported by validated Accelerator Mass Spectrometry technologies for exploring the PK and metabolism of drug candidates directly in humans, both prior to and as part of Phase I, II & III clinical trials

Merowingerplatz 1a Düsseldorf, 40225 Germanyevocatal develops and produces enzymes and fine chemicals.

Sindelfinger Str. 3 D-72070 Tuebingen GermanyEMC Microcollections offers lead structure optimisation, biochemicals, peptides, siderophores, and organic compound collections.

Neusser Str. 39 Düsseldorf, NRW, 40219 GermanyEnzymaster provides a one-stop solution for the development and commercialization of innovative and sustainable enzyme catalysis technologies. With our proprietary BioEngine® platform and long-term experience, we offer R&D services combined with the establishment of complete technology transfer packages and manufacturing collaborations to fine chemical, pharmaceutical, and other industries. Our portfolio includes: • Enzyme panel screening • Customized enzyme kits • Smart engineering of enzymes • Process development • Enzyme preparation by fermentation • Biocatalytic manufacturing

7-9 Mühlenhof Hilden, NRW, 40721 GermanyEnzymaster provides a one-stop solution for the development and commercialization of innovative and sustainable enzyme catalysis technologies. With our proprietary BioEngine® platform and long-term experience, we offer R&D services combined with the establishment of complete technology transfer packages and manufacturing collaborations to fine chemical, pharmaceutical, and other industries. Our portfolio includes: • Enzyme panel screening • Customized enzyme kits • Smart engineering of enzymes • Process development • Enzyme preparation by fermentation • Biocatalytic manufacturing

Eurofins Genomics Anzinger Str. 7a 85560 Ebersberg GermanyEurofins Genomics is a world leader in genomic-based products and services including DNA sequencing, DNA synthesis, and qPCR for both academic and industrial research purposes. In addition to the research sector, Eurofins serves the molecular diagnostic and clinical diagnostic industries with reagents and testing services. Clinical and qPCR testing includes COVID-19 testing, from both patient samples and wastewater. In summary, the company’s strengths are its strong customer orientation, fast service, and high quality.

Altenhöferallee 3 D-60438 Frankfurt am Main. GermanyEvolvus offers expertise in informatics, in vitro screening, medicinal chemistry, and clinical research services.

Großhaderner Steet 9 BioMedical Center Planegg, Bavaria, 82152 GermanyEpiQMAx offers a service for the detection and quantification of proteins and epigenetic modifications. Our workflow is suited for pharmaceutical companies, clinics and individual labs.

Hamburg, HH GermanyEvotec is a leader in the discovery and development of novel small molecule drugs

Am Kugelfang 39 Fürstenfeldbruck, Bavaria, 82256 GermanyOur focus is the synthesis of special oligoribonucleotides for selected pro- jects in IVD-diagnostics, epigenomics, TRIMER-technology and many more, following quality standards which you would appreciate and expect in your own lab. The guidelines for the synthesis standards can be defined by our customers themselves. Through our validated technology platform, our experienced interdisciplinary team and our resolute attitude towards the highest quality in our products we offer tangible advantages to our customers and partners.

Am Klopferspitz 19 Planegg/Martinsried, Bavaria, 82152 GermanyOur focus is the synthesis of special oligoribonucleotides for selected pro- jects in IVD-diagnostics, epigenomics, TRIMER-technology and many more, following quality standards which you would appreciate and expect in your own lab. The guidelines for the synthesis standards can be defined by our customers themselves. Through our validated technology platform, our experienced interdisciplinary team and our resolute attitude towards the highest quality in our products we offer tangible advantages to our customers and partners.

14 Arnimallee Berlin, Berlin, 14195 GermanyWe offer a variety of international degrees in Mathematics, Computer Science and Bioinformatics. Interdisciplinary studies benefit from walking distance to the departments of Physics, Chemistry, Biology, Biochemistry, and the Zuse-Institute Berlin. Our excellence in teaching and research is strongly integrated with the Berlin Mathematical School and the DFG research center Matheon.

Heimeranstrasse 35 80339 Munich GermanyFGK Clinical Research is a full service contract research organization offering clinical development and consulting services.

Oberursel, GermanyFresenius Kabi Product Partnering offers formulation, aseptic filling, quality control, API synthesis and manufacturing services

Bad Homburg, GermanyFresenius Kabi Product Partnering offers formulation, aseptic filling, quality control, API synthesis and manufacturing services

Borkenberg 14 61440 Oberursel GermanyFresenius Kabi Product Partnering offers formulation, aseptic filling, quality control, API synthesis and manufacturing services

Else-Kröner-Strasse 1 61352 Bad Homburg v.d.H. GermanyFresenius Kabi Product Partnering offers formulation, aseptic filling, quality control, API synthesis and manufacturing services

Bad Homburg, HE GermanyFresenius Kabi Product Partnering offers formulation, aseptic filling, quality control, API synthesis and manufacturing services

Konrad-Adenauer-Straße 53754 Sankt Augustin GermanyFraunhofer Institute for Algorithms and Scientific Computing (SCAI) provides products and applications for simulation engineering, bioinformatics, virtual material design, and other related areas.

Jena, Fürstengraben 1, 07737 GermanyThe Friedrich Schiller University in Jena, founded in 1558, with its 21,000 students distributed over ten different faculties leaves its mark on the image of the town. Students of either the university or the university of applied sciences make one quarter of the inhabitants of Jena. So, it is all right to say: There is no university in Jena, Jena is a university! Approximately 340 professors and 6,400 members of staff work at university and university hospital, the latter of which keeps developing into one of the most modern hospitals in Germany. The university puts emphasis on intensely taking care of its students, and works on creating a "Students' Paradise in Jena. (www.studentenparadies.uni-jena.de) Special programmes support students from abroad. When it comes to teaching, Jena University combines tradition and innovation: Apart from medicine, physics, psychology, business studies and economics, or sports, bio and social sciences - all of which are highly ranked - the so-called "smaller subjects", like for instance caucasiology, Romanian or Indo-Germanic studies, are sustained. The wide range of opportunities for studying at Thuringia's only classical university shapes its appearance as well as its attitude: to act without limits - interdisciplinarily and internationally. Therefore, a clear research profile has been established and will be further developed. Jena University's current research profile is composed of five priority research areas: Optics, Photonics and Photonic Technologies Innovative Materials and Technologies Dynamics of Complex Biological Systems Laboratory of the Enlightenment Individuals and Social Change They are completed by three academic cross-sections: Analysis and Management of Complex Systems; Cultural Contexts of Ageing; Europe's Origin: Culture and Religion in the Ancient World and the Middle Ages Up-and-coming young scientists are well prepared for their careers since they are supported by the Jena Graduate Academy. With that, the important topic of "child care" appears on the university's agenda. As one of the founders of the "Jena Alliance for Family", Jena University stands for the compatibility of having children and studying. For this, it has received the Total E-Quality Award. The Friedrich Schiller University is also internationally well-renowned: It is integrated into important networks, like the Coimbra Group, and cooperates with more than 100 universities or academic institutions worldwide. With almost 300 partners within Europe a vivid exchange of students and teachers is taking place. In 2008 Jena has been awarded the title Germany's "City of Sciences". 2008's events were strongly affected by the university's activities. And, in the future, the university wants to sustain a strong influence on teaching, research and culture, nationally and internationally.

Grillparzerstr. 16, 81675 Munich, GermanyFlavine specializes in sourcing of Active Pharmaceutical Ingredients and Pharmaceutical Intermediates within human and animal health.

45 Schwarzenberger Weg Melsungen, HE, 34212 GermanyFaubel & Co. Nachf. GmbH specialize in product labeling.

Gildenstraße 38 48157 Münster GermanyWELCOME Preliminary Statement - Importance of Microirrigation: Since the 70’s, micro irrigation as a technology has matured into a reliable water and fertilization management system for crop production. The usage of micro irrigation is increasing, especially in arid and semi-arid regions as an effective water conservation measure. The micro irrigated area grew from 1.1 million ha in 1986 to about 3.0 million ha in 2000. Micro irrigation today: more than 70 countries covering an area of over 6 million ha. The challenge for 2050 is how to feed 9 billion people without consuming more water. Think smart and apply high efficiency fertilizers to enhance productivity with optimal nutrient supply. VISION "The goal" of the fertigation center of competence is to develop further and deeper knowledge in the defined areas, and to connect with the key participants in order to focus on practical challenges, customers needs & alliances.

Neuss, GermanyFocus Clinical provides phase I-II clinical studies, biomarker research, immune monitoring, immunology, and late clinical pharmacology studies.

Nordstrasse 7 D-66780 Rehlingen, GermanyAfrican Copal Bark CO2-se extract,Ajowain Fruit CO2-se extract (organic), DE-ÖKO-013,Allspice Berries CO2-to extract (organic), Jamaica-Type, DE-ÖKO-013,Allspice Berries CO2-to extract, Jamaica-Type,Amaranth Seed CO2-to extract (organic), DE-ÖKO-013,Angelica Root CO2-se extract,Antimicrobial Blend,Arnica Flower CO2-to extract (organic), 4 % Sesquiterpene lactones, DE-ÖKO-013,Arnica Flower CO2-to extract, 4 % Sesquiterpene lactones,Balm Leaf CO2-se extract (organic), DE-ÖKO-013,Balm Leaf CO2-to extract,Balm Leaf CO2-to extract (organic), DE-ÖKO-013,Basil Leaf CO2-se extract,Black Cumin CO2-to extract (organic), DE-ÖKO-013,Borage Seed CO2-to extract,Borage Seed CO2-to extract (organic), DE-ÖKO-013,Butter CO2-se extract, Cryst. Type,Butter CO2-se extract, Dist. Type,Calamus Root CO2-se extract,Camomile Flower CO2-se extract (integr),Camomile Flower CO2-to extract (integr),Camomile Flower CO2-to extract (organic), DE-ÖKO-013,Caraway CO2-se extract,Caraway CO2-se extract (organic), DE-ÖKO-013,Cardamom CO2-se extract,Cardamom CO2-se extract (organic), DE-ÖKO-013,Cardamom CO2-to extract,Cardamom CO2-to extract (organic), DE-ÖKO-013,Carrot CO2-to extract (organic), with sunflower oil, DE-ÖKO-013,Carrot Seed CO2-se extract,Carrot-Jojoba CO2-to extract (organic), DE-ÖKO-013,Celery Seed CO2-to extract,Chia Seed (Spanish Sage) CO2-to extract (organic), DE-ÖKO-013,Chili CO2-to extract (organic), 3,1 % Capsaicinoids, DE-ÖKO-013,Chili CO2-to extract, 10 % Capsaicinoids,Chili CO2-to extract, 5 % Capsaicinoids,Cinnamon Bark Burmanii CO2-to extract (organic), DE-ÖKO-013,Cinnamon Bark Cassia CO2-to extract,Cinnamon Bark Ceylanicum CO2-se extract,Cinnamon Bark Ceylanicum CO2-se extract (organic), DE-ÖKO-013,Clove Bud CO2-se extract,Clove Bud CO2-se extract (organic), DE-ÖKO-013,Coconut CO2-se extract (organic) DE-ÖKO-013,Coffee CO2-to extract,Coffee CO2-to extract (organic), DE-ÖKO-013,Coriander CO2-se extract,Coriander CO2-to extract (organic), DE-ÖKO-013,Coriander CO2-to extract, 25 % Essent. Oil,Cumin Seed CO2-to extract (organic), DE-ÖKO-013,Curcuma Longa CO2-to extract,Curcuma Longa CO2-to extract (organic), DE-ÖKO-013,Curcuma Xanthorrhiza CO2-se extract,Curcuma Xanthorrhiza CO2-se extract (organic), DE-ÖKO-013,Curcuma Xanthorrhiza CO2-to extract (organic), DE-ÖKO-013,Dill Seed CO2-se extract, Carvone Type,Dill Seed CO2-se extract, Dillapiol Type,Evening Primrose Seed CO2-to extract (organic), DE-ÖKO-013,Fennel CO2-se extract, Bitter Type,Fenugreek Seed CO2-to extract (organic), DE-ÖKO-013,Feverfew CO2-to extract,Flavoxan 14, Rosemary Antioxidant formulation,Flavoxan 25, Rosemary Antioxidant formulation,Frankincense Carteri CO2-se extract,Frankincense Serrata CO2-se extract,Galangal Root CO2-to extract (organic), DE-ÖKO-013,Galbanum CO2-se extract,Garlic CO2-to extract D/E = 50:1,Ginger CO2-extract, powder, 20 % Gingerols,Ginger CO2-se extract,Ginger CO2-to extract,Ginger CO2-to extract (organic), DE-ÖKO-013,Ginger Hot Flavor CO2-to extract,GlucodOX™ Liquid, Guggul-MCT810,Gromwell Root CO2-to extract, standardised and deodorised,Hazelnut CO2-se extract,Hazelnut CO2-se extract (organic), DE-ÖKO-013,Hazelnut CO2-se extract alcohol soluble,Hop CO2-se extract,Hop CO2-to extract,Hop CO2-to extract, flavor reduced, standardised,Juniper Berries CO2-se extract,Kava-Kava Root CO2-to extract, 60 % Kavapyrones,Kiwi Seed CO2-to extract,Lavender Flower CO2-se extract,Lemon Myrtle CO2-se extract (organic), DE-ÖKO-013,Licorice root CO2-to extract with MCT Oil, Variety Uralensis,Lovage Root CO2-se extract,Lovage Root CO2-to extract,Mace CO2-se extract,Mango Ginger CO2-to extract,Marigold CO2-to extract, < 0,1 % Carotenoides, (NOP-organic cert. by CERES),Marigold Flower CO2-to extract (integr),Marigold Flower CO2-to extract (integr), < 0,1 % Carotenoides,Marigold Flower CO2-to extract (organic), DE-ÖKO-013,Marjoram Leaf CO2-se extract,Massoia Bark CO2-se extract,Millet Seed CO2-to extract (organic), DE-ÖKO-013,Musk Seed CO2-se extract,Myrrh CO2-se extract,Nutmeg CO2-se extract (organic), DE-ÖKO-013,Oregano Leaf CO2-se extract (organic), Phenol Type, DE-ÖKO-013,Oregano Leaf CO2-se extract, Terpineol Type,Oregano Leaf CO2-to extract (organic), Phenol Type, DE-ÖKO-013,Oregano Leaf CO2-to extract, Phenol Type,Orris Root CO2-se extract,Orris Root CO2-se extract, 1 % Irone,Orris Root CO2-se extract, 3 % Irones,Paprika CO2-to extract (organic), 40000 C.U., DE-ÖKO-013,Paprika extract, 80000 C.U.,Paprika extract, water dispersible, 40000 C.U.,Parsley Seed CO2-se extract,Peanut CO2-se extract,Peppermint Leaf CO2-se extract,Pomegranate Seed CO2-to extract,Pomegranate Seed CO2-to extract (organic), DE-ÖKO-013,Raspberry Seeds CO2-to extract, (NOP-organic cert. by CERES),Rhatany Root CO2-to extract, standardised,Rosehip CO2-to extract (organic), DE-ÖKO-013,Rosehip Seed CO2-to extract (organic), DE-ÖKO-013,Rosemary Antioxidant extract (organic), 14 % Diterpene Phenols, DE-ÖKO-013,Rosemary Antioxidant extract (organic), 25 % Diterpene Phenols, DE-ÖKO-013,Rosemary Antioxidant extract, 14 % Diterpene Phenols,Rosemary Antioxidant extract, 25 % Diterpene Phenols,Rosemary Antioxidant extract, powder (organic), 25 % Diterpene Phenols, DE-ÖKO-013,Rosemary Antioxidant extract, powder, 25 % Diterpene Phenols,Rosemary Antioxidant extract, water dispersible, 14 % Diterpene Phenols,Rosemary CO2-se extract,Rosemary CO2-se-plus extract,Rosemary CO2-se-plus extract (organic), DE-ÖKO-013,Rosemary CO2-to extract (organic), Camphor Type, DE-ÖKO-013,Sage Antioxidant extract, 25 % Diterpene phenols,Sage Antioxidant extract, 35 % Diterpene Phenols,Sage Officinalis CO2-se extract,Sage Triloba (syn. Fruticosa) CO2-se extract,Sage Triloba (syn. Fruticosa) CO2-se extract (organic), DE-ÖKO-013,Sage Triloba (syn. Fruticosa) CO2-to extract,Sage Triloba (syn. Fruticosa) CO2-to extract, 5 % Oleanolic/Ursolic acid,Sawpalmetto Berries CO2-to extract,Schisandra Fruit CO2-to extract, Variety Chinensis,Schisandra Fruit CO2-to extract, Variety Sphenanthera,Seabuckthorn Berries CO2-to extract,Seabuckthorn Berries CO2-to extract (organic), DE-ÖKO-013,Seabuckthorn Berries CO2-to extract (organic), DE-ÖKO-013,Seabuckthorn Berries CO2-to extract, (NOP-organic cert. by CERES),Seabuckthorn Pulp CO2-to extract,Seabuckthorn Pulp CO2-to extract (organic), DE-ÖKO-013,Seabuckthorn Pulp CO2-to extract (organic), semi-solid lipids, DE-ÖKO-013,Seabuckthorn Pulp CO2-to extract, < 0,1 % Carotenoides,Seabuckthorn Pulp CO2-to extract, semi-solid lipids,Seabuckthorn Seed CO2-to extract,Soy Germ CO2-to extract (organic), DE-ÖKO-013,St. John's Wort CO2-to extract,St. John's Wort CO2-to extract, 10 % Hyperforins,Star anise CO2-se extract,Star anise CO2-se extract (organic), DE-ÖKO-013,Tagetes Flower CO2-to extract,Thyme CO2-se extract,Thyme CO2-to extract,Usnea Lichen CO2-to extract, water dispersible, 4 % Usnic Acids,Vanilla Planifolia CO2-HA-extract, 2 % Vanillin,Vanilla Planifolia CO2-to extract (organic), 12 % Vanillin, DE-ÖKO-013,Vanilla Planifolia CO2-to extract (organic), 26 % Vanillin, DE-ÖKO-013,Vanilla Planifolia CO2-to extract (organic), 95 % Vanillin, DE-ÖKO-013,Vanilla Planifolia CO2-to extract, 12 % Vanillin,Vanilla Planifolia CO2-to extract, 26 % Vanillin,Vanilla Planifolia CO2-to extract, 95 % Vanillin,Vanilla Tahitensis CO2-to extract,Vanilla Tahitensis CO2-to extract, 60 % origin Tahiti,Wheat bran CO2-to extract (organic), DE-ÖKO-013,

63 Thielallee Berlin, Berlin, 14195 GermanyThe mission of the core facility at the Institute of Chemistry and Biochemistry is to provide investigators with state-of-the-art instrumentation along with human expertise to support their research.

Goerzallee 305 b Berlin, 14167 GermanyFormula GmbH develops medicinal products and clinical supplies as well as offers pharmaceutical and analytical development services.

Berlin, Berlin GermanyFormula GmbH develops medicinal products and clinical supplies as well as offers pharmaceutical and analytical development services.

Waldhäuserstrasse 64 D-72076 TübingenFlyion provides screening, assay development, cell lines, electrophysiology, compound profiling, and safety pharmacology.

Tübingen, BW GermanyFlyion provides screening, assay development, cell lines, electrophysiology, compound profiling, and safety pharmacology.

Pottkamp 8 31515 Wunstorf GermanyThe headquarters of Field Research Support is in Wunstorf near Hanover. This site combines a central location with diverse soil types, a wide variety of agronomic and specialty crops and close to JKI in Braunschweig for the registration of their products. The Polish branch of Field Research Support is located in Koscian, south of Poznan and also provides a wide range of agricultural and specialty crops. In cooperation with selected cooperators Field Research Support organizes complete European studies including the preparation of biological dossier for the smooth registration of their pesticides.

Fraunhoferstraße 15 Martinsried, 82152 GermanyFormycon offers formulation development, protein analysis, and manufacturing services.

Fraunhofer Institute of Toxicology and Experimental Medicine (ITEM) Nikolai-Fuchs-Straße 1 30625 Hannover GermanyThe Fraunhofer ITEM offers contract research in the area of human health, with an emphasis on the respiratory tract as a target organ. The focus is on toxicity testing, pre-clinical registration studies, early-phase clinical trials, and chemical risk assessment. Many different test systems are available, including in-vitro, ex-vivo, and in-vivo models. Research activities and services offered range from studies in the areas of occupational and environmental toxicology and consumer protection to pre-clinical and clinical drug research and development, including also GMP process development and manufacturing of biopharmaceuticals for clinical trials. All studies can be performed in compliance with GXP regulations. The Fraunhofer-Gesellschaft is the leading organization for applied research in Europe. Its research activities are conducted by 66 institutes and research units at locations throughout Germany. The Fraunhofer-Gesellschaft employs a staff of nearly 24,000, who work with an annual research budget totaling more than 2 billion euros. Of this sum, around 1.7 billion euros is generated through contract research. More than 70 percent of the Fraunhofer-Gesellschaft’s contract research revenue is derived from contracts with industry and from publicly financed research projects. International collaborations with excellent research partners and innovative companies around the world ensure direct access to regions of the greatest importance to present and future scientific progress and economic development.

2 Floriansbogen Neuried, BY, 82061 GermanyFRIZ Biochem GmbH, founded in Oct. 2004, is a privately held biotech company located in Neuried near Munich. The company initially focused on the development of advanced electronic biochips and gradually integrated the complete workflow of molecular diagnostics in its development efforts. FRIZ Biochem offers novel, highly innovative and broadly applicable molecular diagnostics solutions (instruments, analytical techniques, chemistries, sample preparation etc.) with special emphasis on Point-of-Care applications. FRIZ Biochem meets the challenge of providing a combination of simplification and improved information in a time-frame where the result affects medical intervention. FRIZ Biochem has mainly academic staff with expertise for complex technology development ranging from bioinformatics/software via physics and chemistry to biology and diagnostics. As part of an informal network of renowned research institutes, clinical research organisations, hospitals as well as biotech and pharmaceutical companies it has succeeded in realising a complex interdisciplinary development. Dithiol phosphoreamidite (DTPA) Direct electrical detection of molecular recognition processes forced us to establish a proprietary anchoring of molecular probes on metal surfaces via DTPA (dithiolphosphoreamidite, US7601848, EP1626952). DTPA / DTPA CPG are a disulfide-containing phosphoramidite / solid support to modify synthetic DNA or RNA with multiple thiol groups. These synthons have been developed to improve the attachment of oligonucleotides but also proteins or other molecules to Au, AuNO, Ag, AgNP and other thiol reactive surfaces. The dithiol can be inserted into an oligonucleotide at any position. Download DTPA-flyer DTPA anchoring chemistry allows full control over thermo- and biostability as well as (mixed) loading density for individual application specifications. This DTPA anchoring chemistry allows to provide easily customizable nanoparticle building kits with unique yet individually adjustable physico-chemical properties. Ordering information Nanoparticle Synthesis FRIZ Biochem offers Gold Nanoparticles, users can easily customise to their specific needs and applications. The Au-NP Configurator is an internet based building set providing a variety of configuration options, like: size; anchoring chemistry; density; no of docking oligos; distal modification. Use our Au-NP Configurator to create your own customised Gold Nanoparticles! ... for customised live cell RNA Detection ... or easily develope your own tumor targeting and/or agent transport - with Distal Modifications ... or any functionalisation mixture as well as fully customised functional nano-particle modification Oligonucleotide Synthesis Highest quality multiple modified oligonucleotides are used for FRIZ Biochem's DNA -microarrays. Research & development experience in the synthesis of multiple modified probes enables FRIZ Biochem to offer customers superior reliable technologies & services to optimise their scientific endeavours. A wide variety of modifications can be incorporated into an oligonucleotide at the time of synthesis. When possible, this is done using a modified solid support (CPG) for 3'-modifications or a specialised phosphoramidite reagent for internal and 5'-modifications. Certain modifications are not available as a modified-CPG or phosphoramidite and must be attached to the oligo after synthesis using NHS Ester chemistry. NHS Esters react with free primary amines and result in stable, covalent attachment. A primary amine is therefore added to the oligo during synthesis to permit reaction with the desired NHS Ester. Catalog prices for modifications and prices for standard synthesis are found here.

Floriansbogen 2-4 Neuried, Bavaria, 82061 GermanyFRIZ Biochem GmbH, founded in Oct. 2004, is a privately held biotech company located in Neuried near Munich. The company initially focused on the development of advanced electronic biochips and gradually integrated the complete workflow of molecular diagnostics in its development efforts. FRIZ Biochem offers novel, highly innovative and broadly applicable molecular diagnostics solutions (instruments, analytical techniques, chemistries, sample preparation etc.) with special emphasis on Point-of-Care applications. FRIZ Biochem meets the challenge of providing a combination of simplification and improved information in a time-frame where the result affects medical intervention. FRIZ Biochem has mainly academic staff with expertise for complex technology development ranging from bioinformatics/software via physics and chemistry to biology and diagnostics. As part of an informal network of renowned research institutes, clinical research organisations, hospitals as well as biotech and pharmaceutical companies it has succeeded in realising a complex interdisciplinary development. Dithiol phosphoreamidite (DTPA) Direct electrical detection of molecular recognition processes forced us to establish a proprietary anchoring of molecular probes on metal surfaces via DTPA (dithiolphosphoreamidite, US7601848, EP1626952). DTPA / DTPA CPG are a disulfide-containing phosphoramidite / solid support to modify synthetic DNA or RNA with multiple thiol groups. These synthons have been developed to improve the attachment of oligonucleotides but also proteins or other molecules to Au, AuNO, Ag, AgNP and other thiol reactive surfaces. The dithiol can be inserted into an oligonucleotide at any position. Download DTPA-flyer DTPA anchoring chemistry allows full control over thermo- and biostability as well as (mixed) loading density for individual application specifications. This DTPA anchoring chemistry allows to provide easily customizable nanoparticle building kits with unique yet individually adjustable physico-chemical properties. Ordering information Nanoparticle Synthesis FRIZ Biochem offers Gold Nanoparticles, users can easily customise to their specific needs and applications. The Au-NP Configurator is an internet based building set providing a variety of configuration options, like: size; anchoring chemistry; density; no of docking oligos; distal modification. Use our Au-NP Configurator to create your own customised Gold Nanoparticles! ... for customised live cell RNA Detection ... or easily develope your own tumor targeting and/or agent transport - with Distal Modifications ... or any functionalisation mixture as well as fully customised functional nano-particle modification Oligonucleotide Synthesis Highest quality multiple modified oligonucleotides are used for FRIZ Biochem's DNA -microarrays. Research & development experience in the synthesis of multiple modified probes enables FRIZ Biochem to offer customers superior reliable technologies & services to optimise their scientific endeavours. A wide variety of modifications can be incorporated into an oligonucleotide at the time of synthesis. When possible, this is done using a modified solid support (CPG) for 3'-modifications or a specialised phosphoramidite reagent for internal and 5'-modifications. Certain modifications are not available as a modified-CPG or phosphoramidite and must be attached to the oligo after synthesis using NHS Ester chemistry. NHS Esters react with free primary amines and result in stable, covalent attachment. A primary amine is therefore added to the oligo during synthesis to permit reaction with the desired NHS Ester. Catalog prices for modifications and prices for standard synthesis are found here.

GBA Gesellschaft mbH for Bioanalysis Goldtschmidtstraße 5 21073 HamburgToday the GBA Laboratory Group is represented at 10 different locations throughout Germany. In approximately 15,000 m2 of laboratory space, 430 highly-qualified employees work for GBA, over 35% of whom have an academic background. With the targeted deployment of scientific competencies in the fields of chemistry, biology, bioengineering, chemical engineering, and food chemistry, you are always guaranteed consistently high quality. Our comprehensive analysis services and the personalized consulting provided by our project managers are both specially tailored to your individual demands. We place a high value on dialogue with our customers and on transparency throughout the entire process. Additionally, your individual contact person at the GBA Laboratory Group knows the status of your samples at any given moment and can provide you with a quick overview. Using efficient operational methods, the GBA Laboratory Group shortens the analysis time of your projects. Our modern laboratories work with state-of-the-art technology. The combination of our staff's long-term experience and the latest technology guarantees a comprehensive portfolio of analytical methods in every field, as well as the highest level of quality when processing your orders.

Erich-Martens-Straße 26-32 32257 Bünde GermanyGerresheimer manufactures high quality specialty products made of glass and plastic.

Im Neuenheimer Feld 518 69120 Heidelberg, GermanyGraffinity offers fragment based drug discovery and lead development including technologies in chemical microarrays, fragment screening, SPR label free imaging of protein ligand interactions, and computational chemistry.

Heidelberg, BW GermanyGraffinity offers fragment based drug discovery and lead development including technologies in chemical microarrays, fragment screening, SPR label free imaging of protein ligand interactions, and computational chemistry.

Kirchenstraße 6 Schwabhausen, 85247 GermanyGramsch Laboratories supplies and manufactures polyclonal and monoclonal antisera, peptides, and conjugates.

Schwabhausen, BY, 85247 GermanyGramsch Laboratories supplies and manufactures polyclonal and monoclonal antisera, peptides, and conjugates.

Raiffeisenring 2 68789 St. Leon - Rot, GermanyGeneArchitects offers custom DNA synthesis, linear arrays, and PCR.

Rot an der Rot, BW GermanyGeneArchitects offers custom DNA synthesis, linear arrays, and PCR.

Niederhoechstaedter-Str.62 D-61476 KRONBERG, GermanyGenaxis Biotechnology offers custom oligonucleotide synthesis, DNA sequencing, fluorescence in situ hybridization, antibody production, and peptide antibody production.

Am Exer 10b Wolfenbüttel, D-38302 GermanygeneXplain provides a comprehensive platform for bioinformatic, cheminformatic and systems biological tools.

Anzinger Str. 7a Ebersberg, 85560 GermanyEurofins Genomics – The DNA Universe FAST. We produce and analyse DNA & RNA COMPLETE. We support from research to application RELIABLE. We work with pharma, food, diagnostics, agriculture & biotechnology Reach for the stars. We are glad to assist you! Learn more at eurofinsgenomics.com

GATC Biotech AG European Custom Sequencing Centre Gottfried-Hagen-Straße 20 51105 Cologne GermanyEurofins Genomics – The DNA Universe FAST. We produce and analyse DNA & RNA COMPLETE. We support from research to application RELIABLE. We work with pharma, food, diagnostics, agriculture & biotechnology Reach for the stars. We are glad to assist you! Learn more at eurofinsgenomics.com

Jakob-Stadler Platz 7 Constance, 78467 GermanyEurofins Genomics – The DNA Universe FAST. We produce and analyse DNA & RNA COMPLETE. We support from research to application RELIABLE. We work with pharma, food, diagnostics, agriculture & biotechnology Reach for the stars. We are glad to assist you! Learn more at eurofinsgenomics.com

23 Parkstraße Berlin, Berlin, 13187 GermanyAnalytical service lab offering high level experience in free radical research for cosmetic, pharmaceutical and food industry. Electron Spin Resonance (ESR) spectroscopy- based methodologies aim to characterize both raw materials or finished goods regarding the free radical status or their capacity to prevent or neutralize free radical damage in products or biological samples.

Planegg, Martinsried, GermanyGenPharmTox offers analysis and risk assessment of drugs and chemicals in the area of ADME-Tox.

Leipziger Str. 44, 39120 Magdeburg, GermanyglyXera is a Max Planck Society spin-off, specialized in high-throughput glycoanalysis. glyXera provides a fast and reliable glycoanalysis utilizing a “real” high-throughput system (method/software/database) with superior performance and capacity compared to the glycoanalysis tools available up to now. We offer our clients a sophisticated technology platform and our expertise with respect to glycoanalytical services, tailored to the specific needs of academia, clinics, pharmaceutical and food industries. We guide you for better decisions and help you to perform better and faster during discovery phase, R&D, (clinical) trials and approval of your innovative products (biopharmaceuticals, vaccines, food additives, functional food, etc.), and QA/QC in your production stages. Standard operating procedures (SOP) and a comprehensive quality management system ensure reproducible analyses on highest levels and guarantees transparency through all processes. Our clients include leading pharmaceutical, biotechnology and food companies throughout the world

44 Leipziger Straße Magdeburg, SA, 39120 GermanyglyXera is a Max Planck Society spin-off, specialized in high-throughput glycoanalysis. glyXera provides a fast and reliable glycoanalysis utilizing a “real” high-throughput system (method/software/database) with superior performance and capacity compared to the glycoanalysis tools available up to now. We offer our clients a sophisticated technology platform and our expertise with respect to glycoanalytical services, tailored to the specific needs of academia, clinics, pharmaceutical and food industries. We guide you for better decisions and help you to perform better and faster during discovery phase, R&D, (clinical) trials and approval of your innovative products (biopharmaceuticals, vaccines, food additives, functional food, etc.), and QA/QC in your production stages. Standard operating procedures (SOP) and a comprehensive quality management system ensure reproducible analyses on highest levels and guarantees transparency through all processes. Our clients include leading pharmaceutical, biotechnology and food companies throughout the world

Zielstattstr. 44 München, 81379 GermanyAt Granzer Regulatory Consulting & Services, we provide our clients unique and tailor-made support with European and US regulatory requirements. We offer expert guidance and know-how to optimise the time to market for your products. We have successfully delivered on this promise for nearly 10 years, for more than 250 clients in Europe, North America, Japan, Australia, and Asia. We perform over 150 Scientific Advice meetings per year and in the past two years have filed four complete fully electronic submissions to the EMA. Our mission is to ensure that patients get access to good medicines without unnecessary delay. We employ a staff of experienced consultants who have previous involvement with small and big pharma. We also have access to an established network of specialist consultants with additional and complementary expertise, so that we are able to provide you with know-how unmatched in Europe.

G&P Biosciences 2978 Scott Blvd Santa Clara, CA 95054G&P Biosciences is a Gene and Protein Company dedicated to delivering the finest recombinant DNA/protein products & services to the Life Sciences, Biopharmaceutical and Biomedical Research communities. The Company was founded and is being managed by a team of scientists and experts with extensive knowledge and experience in academic and industrial biotechnologies.

Gera, Thuringia GermanyG&P Biosciences is a Gene and Protein Company dedicated to delivering the finest recombinant DNA/protein products & services to the Life Sciences, Biopharmaceutical and Biomedical Research communities. The Company was founded and is being managed by a team of scientists and experts with extensive knowledge and experience in academic and industrial biotechnologies.

Floriansbogen 2 Neuried, 82061 GermanyGeneWake provides biomarker and gene analysis in the field of oncology.

Feodor-Lynen-Str. 35 Hannover, 30625 GermanyGlycoThera specializes in protein glycosylation mapping, carbohydrate analysis, and protein quality analysis.

Gewerbestrasse 3 78359 Orsingen–Nenzingen GermanyBEHIND EVERY SOLUTION ARE VALUES THAT HELPED US ARRIVE THERE.

Insilico Biotechnology AG Nobelstrasse 15 70569 Stuttgart GermanyInsilico Biotechnology provides strain design, metabolism studies, flux distribution studies, profiling, and design of novel biotechnological processes.

Zeughausmarkt 33 Hamburg, HH, 20459 GermanyStartup offering data science as a service with a focus on machine learning and artificial intelligence. Supports cloud environments and on-premise development.

Hohe Bleichen 21 Hamburg, Hamburg, 20354 GermanyStartup offering data science as a service with a focus on machine learning and artificial intelligence. Supports cloud environments and on-premise development.

Binzen, GermanyGlatt offers pelletization, drug layering/coating, granulation, tablet creation, and processing of products into dosage form.

Werner-Habig-Straße 1, Oelde, Germany 59302GEA Westfalia Separator Group provides separators, decanters, plant construction, and separation technology.

Fidazhofen 16, 88214 Ravensburg, GermanyGxPi offers compliance auditing, training, and consulting services.

Beim Wiesental 22 D-88400 Biberach GermanyGenaxxon BioScience offer amino acid analysis, genomics, protein services, and antibodies.

Ulm, BW GermanyGenaxxon BioScience offer amino acid analysis, genomics, protein services, and antibodies.

Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Building 25B, 5th floor Goethe-University Frankfurt Theodor-Stern-Kai 7 Frankfurt am Main, Hessen, 60590 GermanyGenome Biologics is leaders in therapeutic target discovery and RNA-targeted therapies in Cardiovascular Disease. We have developed a seamless integrated platform that directly couples the output of complex AI-driven human disease genetic analysis – GENIMAPS – to the capacity to model the disease heterogeneity– directly in ex vivo patient-derived heart tissue TrueCardium AND in small and large animals with our patented GENISYST technology. Through application of our integrated technologies – we are Increasing the physiological accuracy and relevance of preclinical drug development and at the same time reducing discovery time and cost. As a platform output, we have developed a rich therapeutic pipeline for Heart Failure, CHIP, Cardiotoxicity and rare disease. We aim to initiate Phase 1 studies with our lead compound in 2022.

GermanyWe develop and apply methods for the model-based description of biological systems, using a data-driven approach by integrating information on multiple scales ranging from single-cell time series to large-scale omics.

Arthur-Scheunert-Allee 114-116 14558 Nuthetal GermanyThe mission of the German Institute of Human Nutrition (DIfE) is to conduct experimental and clinical research in the field of nutrition and health, with the aim of understanding the molecular basis of nutrition-dependent diseases, and of developing new strategies for prevention, treatment, and nutritional recommendations. Scientists at the DIfE pursue these scientific goals by interdisciplinary cooperation comprising a broad spectrum of experimental and epidemiological methods. A particular focus of the institute is research on the most important diseases at present, i.e., obesity, diabetes, and cancer, whose development may involve nutrition-dependent factors. DIfE is an independent foundation and member of the Leibniz Association, an alliance of scientific institutions.

Arthur-Scheunert-Allee 114-116 Nuthetal, 14558 GermanyThe mission of the German Institute of Human Nutrition (DIfE) is to conduct experimental and clinical research in the field of nutrition and health, with the aim of understanding the molecular basis of nutrition-dependent diseases, and of developing new strategies for prevention, treatment, and nutritional recommendations. Scientists at the DIfE pursue these scientific goals by interdisciplinary cooperation comprising a broad spectrum of experimental and epidemiological methods. A particular focus of the institute is research on the most important diseases at present, i.e., obesity, diabetes, and cancer, whose development may involve nutrition-dependent factors. DIfE is an independent foundation and member of the Leibniz Association, an alliance of scientific institutions.

Am Gewerbering 4 / 6 83533 Edling / GermanyGoerlich Pharma offers the production and filling of solid or liquid formulations as well as packaging.

39 Angelhofweg 69259 GermanyGenotype offers DNA services, gene synthesis, and library services.

Hubertusstr. 20 67065 Ludwigshafen am Rhein Deutschland / GermanyGeneON offers DNA markers, polymerases, purification, and PCR products and services.

Max-Planck-Strasse 1 Geesthacht, D - 21502 GermanyGALAB Technologies offers analytical services, contract research services and proprietary tools (AffiSep, AffiSpin, GlycoCleave) for the Health Care, Food and Biopharmaceutical Industry.

Heidelberg, GermanyGlycotope GmbH provides protein services, structural characterization, analytical services, custom assays, profiling, and cytogenetics.

Czerny-Ring 22 Heidelberg, 69115 Germany, EuropeGlycotope GmbH provides protein services, structural characterization, analytical services, custom assays, profiling, and cytogenetics.

Robert-Roessle-Str. 10 13125 Berlin GermanyGlycotope GmbH provides protein services, structural characterization, analytical services, custom assays, profiling, and cytogenetics.

Nuremberg, BY GermanyGfK is one of the world’s leading market research companies, a full-service institute, which regards itself as a supplier of knowledge. GfK is the trusted source of relevant market and consumer information that enables its clients to make smarter decisions. More than 13,000 market research experts combine their passion with GfK’s long-standing data science experience. This allows GfK to deliver vital global insights matched with local market intelligence from more than 100 countries. By using innovative technologies and data sciences, GfK turns big data into smart data, enabling its clients to improve their competitive edge and enrich consumers' experiences and choices.

Im Neuenheimer Feld 584 Heidelberg, Baden-Württemberg, 69120 GermanyGen- H offers all types of DNA constructs to develop transgenic animal models. Our second field of expertise is the modification and strain engineering in E.coli.

Hinter den Hofen 24 21769 Lamstedt GermanyGAB Consulting is a leading consulting company offering comprehensive registration services for the chemical industry in Europe and overseas. We meet your needs by providing competent and flexible regulatory and scientific expertise to ensure that your product gets registered. Our full range of services includes initial data gap analyses and dossier preparation, as well as risk assessments, expert statements and dossier defence. Our project managers and senior specialists are always available to help you and solve any issues with authorities’ requests or to answer any general questions you may have. Our goal is that you can sell your product as soon as possible.

Hans-Böckler-Allee 20 Hannover, 30173 GermanyGirindus offers their expertise in oligonucleotide and small molecule API radiolabeling, manufacturing, and scale up.

Hanover, NDS GermanyGirindus offers their expertise in oligonucleotide and small molecule API radiolabeling, manufacturing, and scale up.

Germany

Rischerstr. 12 D-69123 Wieblingen GermanyGerbu is a distributor of adjuvants, research kits, and products for Dojindo, Fischer, and Nacalai.

Freiburg, GermanyGreenovation Biotech provides cell line production, efficacy and performance optimization, and glycoprotein prototypes.

Weipertstr. 8-10 D-74076 Heilbron GermanyGreenovation Biotech provides cell line production, efficacy and performance optimization, and glycoprotein prototypes.

Heilbronn, BW GermanyGreenovation Biotech provides cell line production, efficacy and performance optimization, and glycoprotein prototypes.

9 Leibnizstraße Neu-Ulm, BY, 89231 Germany

11B Fraunhoferstraße Planegg, BY, 82152 Germany

11B Fraunhoferstraße Planegg, BY, 82152 Germany

4 Am Haag Gräfelfing, BY, 82166 Germany

Fraunhofer Straße 11a Martinsried, 82152 Germany

Ernst-Abbe-Straße 40 Ulm, 89079 Germany

2 route de remich Luxembourg Ellange, Choose a State, 5690 LuxembourgGeneCust offers gene synthesis, cloning, DNA array, peptide synthesis, and adenovirus services.

Landsteinerstr. 1 Leipzig, Saxony, 04103 GermanyHaema AG is active in the field of blood plasma and whole blood collection and operates a number of donation centres in Germany. Haema is mainly collecting plasma for fractionation and further manufacture into plasma-derived medicinal products. Haema is further collecting whole blood and other blood components such as leukopaks as well as blood-derived products as raw materials for research and development as well as diagnostic purposes. Haema is partner of the Grifols group. Grifols is a pharmaceutical and biotherapeutics group that develops, manufactures, and distributes plasma-derived medicinal products for the treatment of blood and immune diseases. Human plasma for fractiona-tion is a key raw material for Grifols.

Waltershofener Str.17 79111 Freiburg GermanyAntibody discovery against any target Genovac offers the world’s most advanced antibody discovery solutions. Our innovative immunization technologies combined with our advanced hybridoma and Berkeley Lights Beacon platform provides success against the most challenging targets. We partner with all leading transgenic animal companies and offer everything from cDNA synthesis to antibody sequencing.

9 Hafenstraße Tornesch, SH, 25436 GermanyHanns G. Werner GmbH + Co. KG is a medium-sized, family-owned company, specialized on dragées.

Plant 1 Bahnhofstrasse 74 429 Sulzbach-Laufen GermanyHolopack Verpackungstechnik provides contract filling services.

Hohenzollernring 38 Koln, D-5067 GermanyElisa kits, antibodies, proteins and peptides for life science research - these are some of the topics with which Hölzel Diagnostika has been successfully working for years. The trading company based in Cologne was founded in 1993 by the diploma biologist Veit Hölzel. Since then, the Hölzel Diagnostika team, consisting of biologists as well as IT, sales and marketing experts, is working daily to provide suitable products for industrial and pharmaceutical companies as well as universities and laboratories from the worldwide range. A wide product range, a worldwide customer base and a lot of experience are the results of this work. Benefit from this long-standing know-how and select the Elisa kits, ELIspots, proteins, peptides, genes, inhibitors and array assays suitable for you from around three million products from well-known and international manufacturers. Hölzel Diagnostika ensures that you receive your desired product - quickly, safely and at a fair price. Service @ Hölzel Individual advice and support by your personal contact at Hölzel. As soon as you have decided on a product, even if we do not have it in our assortment, we will gladly take over the entire process. This includes the order, the dispatch and the customs processing as well as the after sales service. For product questions, we can help you with our comprehensive network. Through our close cooperation with more than 150 manufacturers worldwide, we are in direct contact with the expert teams. If required manufacturer products are no longer produced, we will find the suitable alternative for you. Monthly changing exclusive discounts on the products our manufacturers. Procurement of test kits, burr checks and additional material possible.

Xantener Straße 1 P.O.Box 10 17 63 45417 Mülheim an der RuhrHARKE offers chemicals, polymers, solubility and bioavailability products and services.

Carl-Neuberg-Str. 1 30625 HannoverHannover Medical School focuses on research in anatomy, biochemistry, pathology, genetics, pharmacology, and toxicology.

Central Airport Berlin-Tempelhof Hangar VI 12101 Berlin GermanyHybrid Organ offers primary cell isolation from human organs, cell regeneration, and expansion services.

Max-Lebsche-Platz 31 München, 81377 GermanyThe Helmholtz Zentrum München - German Research Center for Environmental Health, the Ludwig-Maximilians-Universität with its University Hospital and the Asklepios Fachkliniken München-Gauting recently established one of the largest translational centers for chronic lung diseases worldwide. The Helmholtz Zentrum München is an expert in bridging fundamental experimental research and applied medical research. The Ludwig-Maximilians-Universität is one of the Top-Level-Universities of the German Excellence Initiative, its medical faculty provides excellent results in the area of pulmonary research and medical treatment. The Asklepios Fachkliniken München-Gauting is one of the leading hospitals in Germany that is specialized in lung diseases. The research in the CPC is focused on chronic lung diseases. CPC-scientists integrate methods of molecular and cell biology, pharmacology, molecular pathology and clinical medicine in order to develop new diagnostical tools and therapies for chronic lung diseases.

Düsseldorf, GermanyLooking back on nearly 140 years of success, Henkel’s vision is to become a global leader in brands and technologies. Henkel holds globally leading market positions both in the consumer and industrial sector today and is well known for brands such as Persil, Schwarzkopf and Loctite. The company is organized into three globally operating business units: Laundry & Home Care, Beauty Care and Adhesive Technologies. The Dax-30 company is headquartered in Düsseldorf, Germany, and proud of its almost 50,000 employees from more than 120 nations worldwide. Henkel is globally active and has as strong presence in emerging markets

Inhoffenstraße 7 Braunschweig 38124 GermanyHelmholtz Centre for Infection Research provides cell-based screening, biological services, and mouse genetic studies.

9 Josef-Engert-Straße Regensburg, BY, 93053 GermanyHEPA cult was founded as a spin-off of the University Hospital Regensburg into being in the year of 2002. The founding team has developed a technology platform for the isolation and preservation of human liver cells and established. From this knowledge base of the company a number of innovative products and services for the research-based pharmaceutical industry and publicly funded research institutions are generated. Human liver cells for Applied Sciences and Pharmaceutical Research hepa cult provides in vitro to systems that are derived from human liver tissue. The liver is the central Verstoffwechslungsorgan for drugs. Only with cells from the human liver, the effect of a drug on humans can be tested satisfactorily. Hepa cult is a supplier and service provider for the pharmaceutical industry and the scientific community. Hepa cult permits in some areas the abandonment of animal testing, reduced the risk of new drugs and provides research high-quality, state-of-the-art models. Innovative technologies protect the donor material HEPA cult used preservation techniques which do not adversely affect the quality of the material. hepa cult wants long term humane through constant technological improvements liver cells as in vitro model under provide standardized and validated conditions for scientific use. Regenerative medicine and new therapies hepa cult seeks to gradually open up new fields of application for its proprietary technologies. Here the developed know-how is transferred to other body tissues and body organs. Hepa cult works in research projects with partners on innovative concepts for a regeneration of liver tissue and to novel therapeutic strategies, for. Example, in the field of Gastro Tere Logie, Hepatology, virology and transplantation medicine.

Marchioninistraße 25 81377 Munich

Hameln, Lower Saxony, GermanyHameln provides custom development, biological studies, clinical trials, and GLP services

Im Neuenheimer Feld 583 Heidelberg GermanyHummingbird offers full support for successful biomarker discovery, screening procedures, validation, diagnostics, drug discovery, treatment monitoring, and safety. Preparation and measurement following robust SOPs - additional SOPs for all other major biofluids Identification of signatures using unique bioinformatics platform

Weismüllerstraße 50 Frankfurt, 60314 GermanyHWI pharma servcies GmbH offers innovative technolgies and services for Pharma and Biotech-industries, particularly for active ingredients and medicinal products with small and large molecules. Our end-to-end service concept covers all phases along the pharmaceutical value chain. Our service portfolio ranges from formulation development, analytical development and quality control, manufacturing of clinical batches and smaller market batches to pre-clinical development, pharmacovigilance and GxP services. At Ruelzheim site, the focus is on development and validation of analytical methods, trace analysis, troubleshooting, quality control and stability testing. The laboratories are GMP- and FDA-certified and hold a manufacturing licence for the release of clinical and market batches. We have our own GVP-compliant pharmacovigilance system and offer extensive support regarding pharmacovigilance and GxP services. Frankfurt site specialises in the development and small batch production of liquid and semi-solid medicinal products for external, nasal and parenteral use. Active ingredients can be handled up to OEB class 5. At Appenweier site, the focus is on development of oral solid medicinal products, characterisation of active substances and manufacturing of clinical trial samples and small-scale batches. HWI is a family-owned, independent service partner in the pharma and biotech sector. We stands for quality, flexibility, competence and reliability.

Straßburger Straße 77 Appenweier, 77767 GermanyHWI pharma servcies GmbH offers innovative technolgies and services for Pharma and Biotech-industries, particularly for active ingredients and medicinal products with small and large molecules. Our end-to-end service concept covers all phases along the pharmaceutical value chain. Our service portfolio ranges from formulation development, analytical development and quality control, manufacturing of clinical batches and smaller market batches to pre-clinical development, pharmacovigilance and GxP services. At Ruelzheim site, the focus is on development and validation of analytical methods, trace analysis, troubleshooting, quality control and stability testing. The laboratories are GMP- and FDA-certified and hold a manufacturing licence for the release of clinical and market batches. We have our own GVP-compliant pharmacovigilance system and offer extensive support regarding pharmacovigilance and GxP services. Frankfurt site specialises in the development and small batch production of liquid and semi-solid medicinal products for external, nasal and parenteral use. Active ingredients can be handled up to OEB class 5. At Appenweier site, the focus is on development of oral solid medicinal products, characterisation of active substances and manufacturing of clinical trial samples and small-scale batches. HWI is a family-owned, independent service partner in the pharma and biotech sector. We stands for quality, flexibility, competence and reliability.

Weismüllerstraße 50 Frankfurt, 60314 GermanyHWI pharma servcies GmbH offers innovative technolgies and services for Pharma and Biotech-industries, particularly for active ingredients and medicinal products with small and large molecules. Our end-to-end service concept covers all phases along the pharmaceutical value chain. Our service portfolio ranges from formulation development, analytical development and quality control, manufacturing of clinical batches and smaller market batches to pre-clinical development, pharmacovigilance and GxP services. At Ruelzheim site, the focus is on development and validation of analytical methods, trace analysis, troubleshooting, quality control and stability testing. The laboratories are GMP- and FDA-certified and hold a manufacturing licence for the release of clinical and market batches. We have our own GVP-compliant pharmacovigilance system and offer extensive support regarding pharmacovigilance and GxP services. Frankfurt site specialises in the development and small batch production of liquid and semi-solid medicinal products for external, nasal and parenteral use. Active ingredients can be handled up to OEB class 5. At Appenweier site, the focus is on development of oral solid medicinal products, characterisation of active substances and manufacturing of clinical trial samples and small-scale batches. HWI is a family-owned, independent service partner in the pharma and biotech sector. We stands for quality, flexibility, competence and reliability.

8 Rheinzaberner Straße Rülzheim, RP, 76761 GermanyHWI pharma servcies GmbH offers innovative technolgies and services for Pharma and Biotech-industries, particularly for active ingredients and medicinal products with small and large molecules. Our end-to-end service concept covers all phases along the pharmaceutical value chain. Our service portfolio ranges from formulation development, analytical development and quality control, manufacturing of clinical batches and smaller market batches to pre-clinical development, pharmacovigilance and GxP services. At Ruelzheim site, the focus is on development and validation of analytical methods, trace analysis, troubleshooting, quality control and stability testing. The laboratories are GMP- and FDA-certified and hold a manufacturing licence for the release of clinical and market batches. We have our own GVP-compliant pharmacovigilance system and offer extensive support regarding pharmacovigilance and GxP services. Frankfurt site specialises in the development and small batch production of liquid and semi-solid medicinal products for external, nasal and parenteral use. Active ingredients can be handled up to OEB class 5. At Appenweier site, the focus is on development of oral solid medicinal products, characterisation of active substances and manufacturing of clinical trial samples and small-scale batches. HWI is a family-owned, independent service partner in the pharma and biotech sector. We stands for quality, flexibility, competence and reliability.

8 Rheinzaberner Straße Rülzheim, RP, 76761 GermanyHWI pharma servcies GmbH offers innovative technolgies and services for Pharma and Biotech-industries, particularly for active ingredients and medicinal products with small and large molecules. Our end-to-end service concept covers all phases along the pharmaceutical value chain. Our service portfolio ranges from formulation development, analytical development and quality control, manufacturing of clinical batches and smaller market batches to pre-clinical development, pharmacovigilance and GxP services. At Ruelzheim site, the focus is on development and validation of analytical methods, trace analysis, troubleshooting, quality control and stability testing. The laboratories are GMP- and FDA-certified and hold a manufacturing licence for the release of clinical and market batches. We have our own GVP-compliant pharmacovigilance system and offer extensive support regarding pharmacovigilance and GxP services. Frankfurt site specialises in the development and small batch production of liquid and semi-solid medicinal products for external, nasal and parenteral use. Active ingredients can be handled up to OEB class 5. At Appenweier site, the focus is on development of oral solid medicinal products, characterisation of active substances and manufacturing of clinical trial samples and small-scale batches. HWI is a family-owned, independent service partner in the pharma and biotech sector. We stands for quality, flexibility, competence and reliability.

Rheinzaberner Straße 8 Rülzheim, 76761 GermanyHWI pharma servcies GmbH offers innovative technolgies and services for Pharma and Biotech-industries, particularly for active ingredients and medicinal products with small and large molecules. Our end-to-end service concept covers all phases along the pharmaceutical value chain. Our service portfolio ranges from formulation development, analytical development and quality control, manufacturing of clinical batches and smaller market batches to pre-clinical development, pharmacovigilance and GxP services. At Ruelzheim site, the focus is on development and validation of analytical methods, trace analysis, troubleshooting, quality control and stability testing. The laboratories are GMP- and FDA-certified and hold a manufacturing licence for the release of clinical and market batches. We have our own GVP-compliant pharmacovigilance system and offer extensive support regarding pharmacovigilance and GxP services. Frankfurt site specialises in the development and small batch production of liquid and semi-solid medicinal products for external, nasal and parenteral use. Active ingredients can be handled up to OEB class 5. At Appenweier site, the focus is on development of oral solid medicinal products, characterisation of active substances and manufacturing of clinical trial samples and small-scale batches. HWI is a family-owned, independent service partner in the pharma and biotech sector. We stands for quality, flexibility, competence and reliability.

Pfaffenrieder Str. 5-7 Wolfratshausen, 82515 GermanyHaupt Pharma offers clinical trial supply, contract manufacturing, and packaging services.

Willstätterstr. 11, D-40549 Düsseldorf, GermanyHach Company manufactures and distributes analytical instruments and reagents used to test the quality of water and other liquids.

Albrechtstraße 14 80636 Munich, GermanyHarrison Clinical Research provides regulatory surveillance, quality assurance, clinical operations in phase II-IV, and medical writing.

Munich, BY GermanyHarrison Clinical Research provides regulatory surveillance, quality assurance, clinical operations in phase II-IV, and medical writing.

HELM AG, Nordkanalstrasse 28 D-20097 Hamburg, GermanyHelm AG provides chemicals, fertilizers, plastics, APIs, and development projects.

Liebigstraße 1-2 Florsheim am Main, 65439 GermanHennig Arzneimittel offers contract manufacturing services.

Flörsheim am Main, HE, 65439 GermanyHennig Arzneimittel offers contract manufacturing services.

Bötzinger Str. 29, 79111 Freiburg im Breisgau, DeutschlandThe Hydrotox GmbH was founded in 1989 as a contract research laboratory and consultancy for assessing chemicals and mixtures by means of biological test systems. For this, internationally accepted and standardised test methods for the assessment of biodegradability, ecotoxicity and genotoxicity are applied. The focusing of our business strategy is based on: Contract research related to environmental topics for industry and public authorities Routine testing in compliance with the principles of "Good Laboratory Practice" (GLP) The Hydrotox team consists of biologists, chemists, hydrologists, environmental engineers and technical assistants. We have an extensive expertise in studies with chemicals, pharmaceuticals, biocides, detergents, lubricants and cosmetics as well as other products and environmental samples. The methods applied by Hydrotox GmbH are adapted and improved continuously to the current standard of knowledge and are validated by participation in international ring tests. All studies are performed according to the principles of GLP or ISO 17025 which assures our high quality and comparability of the results. The combination of laboratory and advisory services is an essential element of the business of the Hydrotox GmbH.

Heinrich-Damerow-Straße 1 D-06120 Halle (Saale)

Kurt-Fischer-Straße 55 22926 Ahrensburg, GermanyThe Hydrosol team develops tailor-made stabilising systems and emulsifying systems for dairy products, ice cream, deli foods, ready meals, meat and sausage products and also integrated compounds for deli specialities and desserts. With commitment and know-how we have made our company a centre of excellence in the field of stabilisers and emulsifiers. We are familiar with the properties of every single stabiliser and every single emulsifier. That enables us to create systems whose synergisms make customized solutions possible.

46 Kreuzauer Straße Düren, NRW, 52355 GermanyHD-Separations GmbH is a small company that offers chromatographic services and products for chromatography. Founders and employees can look back on many years of professional experience with (semi-)preparative chromatography in the pharmaceutical industry and in instrumental analysis. The focus is on the semi-preparative (small-scale) purification of intermediate and final products from research, the isolation of unknown impurities as well as isomer and enantiomeric separations on the semipreparative scale. Both high-performance liquid chromatography (HPLC) and supercritical-gas chromatography (SFC) chromatography are used as the technique.

Industry Park Niederau Kreuzauer Str 46th Düren , 52355 GermanyHD-Separations GmbH is a small company that offers chromatographic services and products for chromatography. Founders and employees can look back on many years of professional experience with (semi-)preparative chromatography in the pharmaceutical industry and in instrumental analysis. The focus is on the semi-preparative (small-scale) purification of intermediate and final products from research, the isolation of unknown impurities as well as isomer and enantiomeric separations on the semipreparative scale. Both high-performance liquid chromatography (HPLC) and supercritical-gas chromatography (SFC) chromatography are used as the technique.

Hansaring 10 Köln, D 50670 GermanyHölzel Diagnostika Handels offers a huge selection of Elisa Kits, Antibodies, Proteins, ELIspots, Peptides and Array Assays.

Cologne, NRW GermanyHölzel Diagnostika Handels offers a huge selection of Elisa Kits, Antibodies, Proteins, ELIspots, Peptides and Array Assays.

Hansaring 10 50670 Cologne, GermanyHoelzel Diagnostika supplies and distributes ELISA kits, ELIspots, peptides, and antibodies.

Georg-Kalb-Straße 5-8 82049 Großhesselohe/Munich GermanyHermes Arzneimittel specializes in the development and manufacture of effervescent tablets and other soluble dosage forms.

1 Ingolstädter Landstraße Oberschleißheim, BY, 85764 Germanyell sorting is a technique that offers researchers the possibility of enriching specific cell types from the blood or tissue in order to search specifically for disease causes and to develop treatment methods. The Cell Sorting Services Unit at the Hämatologikum of Helmholtz Zentrum München provides single-cell sorting and special flow cytometric analyses for Center scientists and scientists from other institutions.

B2C-Chemistry An den Drei Hasen, Karl-Hermann-Flach Straße 34, Oberursel 61440, GermanyHamari Chemicals is specialized in the manufacture of APIs and pharmaceutical intermediates, food additives, amino acid derivatives, nutritional ingredients, peptide, cosmetic substances, dietary supplements

Am Neuland 3 Bernried am Starnberger See, 82347 GermanyHyglos offers endotoxin detection and removal in addition to gene to protein services.

Bernried am Starnberger See, BY, 82347 GermanyHyglos offers endotoxin detection and removal in addition to gene to protein services.

Wrangelstrasse 11-12 12165 Berlin GermanyHS Diagnomics is a Berlin based company founded in 2012. We are specialists in T-cell beta receptor (TCRbeta / CDR3) profiling by ultra-deep sequencing. With our proprietary technology, tested and optimized in hundreds of samples, we can display the T-cell beta repertoire in blood and tissue samples in maximal resolution, up to the single cell level and up to every single nucleotide and translated peptide of the TCR. Within days our customers will receive an atomic view on TCRbeta profiles, a key to understanding of the adaptive immune system. Moreover, our TCRsafe procedure allows the simultaneous analysis of cohorts of samples, with detailed overlap analysis – a cutting-edge tool for systematic studies of the adaptive immune system. Our mission and our offer to the market is a robust and integrated service to explore TCRbeta profiles in yet unprecedented resolution. Our customers send us the samples, the rest of the procedure is with us. Our experienced team of molecular biologists, technicians and bioinformaticians will deliver TCRbeta-profiles comprising thousands of clonotypes, which are characterized base by base of their CDR3 regions. All results are displayed in compact tables which can be easily managed by customers locally, detailed reports will document every relevant result of our analysis. We believe that our T-cell profiling technology will open a new field of diagnostics and medicine, with key features of individual immune systems being uncovered. Our technology is based on a multistep PCR-amplification with proprietary primer systems, which amplify TCRbeta specific regions directly from genomic DNA. With an inbuilt 2-fold contamination protection our TCRsafe protocol is superior to other technologies, since it eliminates spurious intake of alien samples very efficiently. Following state of the art deep-sequencing HSDiagnomics uses in-house developed bioinformatics tools to condense million of raw sequence reads into clusters (clonotypes).

HWI pharma services GmbH Rheinzaberner Str. 8 Rülzheim , 76761 GermanyThe HWI group offers a wide range of services and covers the entire life cycle of pharmaceuticals, medical devices and other related products.

Waldseeweg 6 Berlin, Berlin, 13467 GermanyThe firm Herbalist & Doc is a young, dynamic pharmaceutical company, founded in 1997. Company leaders Dr. Jörg Grünwald and Christof Jänicke both had many years of experience in leading positions in the pharmaceutical industry before they founded Herbalist & Doc. Both Dr. Grünwald and Mr Jänicke use their industry experience and botanical knowledge to market safe, effective, natural plant medicines, which are beneficial to human health. Herbalist & Doc places great value on plant medicines and natural therapies. Many of our products are made from medicinal plants that have been recognized for thousands of years for their healing properties, or from recently discovered medicinal plants. We place a high value on scientifically proven effectiveness, stable galenic forms and high quality in all our natural health care products. The information, concerning our products, found on the following pages is in accordance with the legal requirements of the Federal Republic of Germany medicine law (Arzneimittelgesetz [AMG]), and medical products advertisement law (Heilmittelwerbegesetz [HWG]). We take no responsibility for information which does not comply with the laws of other countries.

Renteilichtung 1 DE-45134 EssenHaemochrom Diagnostica provides haemostasis, endotoxin and pyrogene analysis and services.

Fahrenheit 1 Bremen, 28359 GermanyHansa Fine Chemicals (HFC) offers production of organic, heterocyclic, fluoro-and phosphorus-organic building blocks and custom synthesis services for specialty chemicals.

Steinweg 3-5 Frankfurt Am Main, Hessen, 60313 Germany

Stubenwald-Allee 8a D-64625 BensheimImmundiagnostik offers immunoassays, molecular biology tests, photometric assays, and antibody services.

Bensheim, HE, 64625 GermanyImmundiagnostik offers immunoassays, molecular biology tests, photometric assays, and antibody services.

Mainzer Landstrasse 49 60329 Frankfurt am Main GermanyImmunodiagnostic Systems (IDS) develops immunoassays and automated immunoanalyser technologies for use in clinical and research laboratories.

IonGate Biosciences GmbH Industriepark Hoescht, D52 65926 Frankfurt, Main GermanyIonGate Biosciences provides target characterization, assay development, and transporter screening.

Lademannbogen 61 Hamburg, 22339 GermanyIPM BIOTECH offers services in molecular immunology, cellular immunology, and molecular genetics in addition to offering cellular function assays including ADCC/CDC, proliferation, and apoptosis studies.

Stuttgart, BW GermanyInsilico Biotechnology is a market-leader in providing solutions and software for the simulation of living cells. - See more at: http://www.insilico-biotechnology.com/en/about-us/company/company-profile#sthash.ACtUAcZY.dpuf

Waldhäuser Str. 64 Tübingen, 72076 GermanyFounded in July 2019 as a spin-off of the INTAVIS Bioanalytical Instruments AG, the INTAVIS Peptide Services GmbH & Co. KG offer with more than 30 years of accumulated knowledge in custom peptide synthesis a customized peptide synthesis service that excels in flexibility, reliability and agility. Whether you are researching signal transduction, protein interaction, proteomics, immunology, vaccine development, personalized cancer treatment or antisense inhibition, Intavis Peptide Services will offer you an individual cost-effective solution to bring your research forward.

Waldhäuser Str. 64 Tübingen, 72076 GermanyFounded in July 2019 as a spin-off of the INTAVIS Bioanalytical Instruments AG, the INTAVIS Peptide Services GmbH & Co. KG offer with more than 30 years of accumulated knowledge in custom peptide synthesis a customized peptide synthesis service that excels in flexibility, reliability and agility. Whether you are researching signal transduction, protein interaction, proteomics, immunology, vaccine development, personalized cancer treatment or antisense inhibition, Intavis Peptide Services will offer you an individual cost-effective solution to bring your research forward.

64 Waldhäuser Straße Tübingen, BW, 72076 GermanyFounded in July 2019 as a spin-off of the INTAVIS Bioanalytical Instruments AG, the INTAVIS Peptide Services GmbH & Co. KG offer with more than 30 years of accumulated knowledge in custom peptide synthesis a customized peptide synthesis service that excels in flexibility, reliability and agility. Whether you are researching signal transduction, protein interaction, proteomics, immunology, vaccine development, personalized cancer treatment or antisense inhibition, Intavis Peptide Services will offer you an individual cost-effective solution to bring your research forward.

248 Widdersdorfer Straße Köln, NRW, 50933 GermanyFounded in July 2019 as a spin-off of the INTAVIS Bioanalytical Instruments AG, the INTAVIS Peptide Services GmbH & Co. KG offer with more than 30 years of accumulated knowledge in custom peptide synthesis a customized peptide synthesis service that excels in flexibility, reliability and agility. Whether you are researching signal transduction, protein interaction, proteomics, immunology, vaccine development, personalized cancer treatment or antisense inhibition, Intavis Peptide Services will offer you an individual cost-effective solution to bring your research forward.

2 Artilleriestraße Jülich, NRW, 52428 GermanyinnoVitro GmbH is a Contract Research Organisation operating from Jülich, Germany providing human-based cardiac risk and efficacy screening services for Pharma, Biotech and Academia worldwide. Each service is custom-tailored by an expert team in close cooperation with the client and carried out as end-to-end study report in less than 6 weeks. Screening parameters encompass structural and functional endpoints of human iPSC-derived cardiomyocytes, analysed with a high throughput 96-well hybrid system. Drug-induced changes of healthy or diseased cells can be assessed regarding cellular and electrophysiological properties (CardioExcyte Module) as well as changes in contractility (FLEXcyte 96 Module). Here, adult-like contractile force analysis is provided through flexible membranes mimicking in vivo conditions of the human heart.

c/o TU Braunschweig "Carola-Wilhelmina" Hagenring 30 Braunschweig, Niedersachsen, 38106 GermanyWe are working on the field of the synthesis of small molecules. We can support your demand from small amounts (mg- and g-scale) up to huge amounts ( kg and multiple mt). Some examples of substances we generate in kg-Scale: - Meroquinine [ - C10,C11-Didehydro-cinchonidine - Cupreine - Cupreidine - Quininic acid [86-68-0], (6-Methoxy-quinoline-4-carboxylic acid)

Leonhardstraße 27 Braunschweig, Niedersachsen, 38102 GermanyWe are working on the field of the synthesis of small molecules. We can support your demand from small amounts (mg- and g-scale) up to huge amounts ( kg and multiple mt). Some examples of substances we generate in kg-Scale: - Meroquinine [ - C10,C11-Didehydro-cinchonidine - Cupreine - Cupreidine - Quininic acid [86-68-0], (6-Methoxy-quinoline-4-carboxylic acid)

c/o TU Braunschweig "Carola-Wilhelmina" Braunschweig, Niedersachsen, 38106 GermanyWe are working on the field of the synthesis of small molecules. We can support your demand from small amounts (mg- and g-scale) up to huge amounts ( kg and multiple mt). Some examples of substances we generate in kg-Scale: - Meroquinine [ - C10,C11-Didehydro-cinchonidine - Cupreine - Cupreidine - Quininic acid [86-68-0], (6-Methoxy-quinoline-4-carboxylic acid)

c/o TU Braunschweig "Carola-Wilhelmina" Braunschweig, Niedersachsen, 38106 GermanyWe are working on the field of the synthesis of small molecules. We can support your demand from small amounts (mg- and g-scale) up to huge amounts ( kg and multiple mt). Some examples of substances we generate in kg-Scale: - Meroquinine [ - C10,C11-Didehydro-cinchonidine - Cupreine - Cupreidine - Quininic acid [86-68-0], (6-Methoxy-quinoline-4-carboxylic acid)

Hanferstr. 28 D-79108 Freiburg, GermanyiOMEDICO provides clinical research services, electronic data capture, and site management.

Wehr, BW GermanyIGS Aerosols offers contract filling of pharmaceutical, cosmetic and chemical-technical products.

Morellstrasse 33 86159 Augsburg / Germany

Aspenhaustr. 25 D-72770 Reutlingen GermanyIBT Systems provides custom biotinylation, immunoassay development, and immunoassay kits.

9 Joachim-Jungius-Straße Rostock, MV, 18059 GermanyThe INNOPROOF GmbH is an accredited laboratory for testing mechanically loaded implants. With our machine park, we offer testing services in the area of endoprosthetics, traumatology, spinal surgery, breast augmentation and implant dentistry as well as materials and coatings.

Ingolstädter Landstraße 1 85764 Neuherberg / München GermanInfrafrontier offers animal models, phenotyping, genotyping, proteomics, and assay services.

Goettingen, GermanyIBA provides custom DNA and RNA production with fluorescent labels and modifications, aptamers, cloning, transfection, protein expression and purification to detection, immobilization, and T-cell isolation.

Rudolf-Wissell-Str. 28 Goettingen, 37079 GermanyIBA provides custom DNA and RNA production with fluorescent labels and modifications, aptamers, cloning, transfection, protein expression and purification to detection, immobilization, and T-cell isolation.

4 Ebinger Straße Straßberg, BW, 72479 GermanyImmune Analytics as specialist CRO offers immunomonitoring services with a strong focus on the analysis of preclinical and clinical samples by EliSpot (enzyme-linked immuno spot) or FluoroSpot supported by a range of other methods like ELISA, flow cytometry and immune arrays. With a dedicated team of scientists, project manager and QA colleagues, Immune Analytics is specialized in the realization of projects with a high degree of assay customization. Besides the excellent scientific and technical competence, Immune Analytics adheres to international regulatory requirements of preclinical and clinical studies and is certified according to Good Laboratory Practice (GLP) and Good Clinical Laboratory Practice (GCLP). Immune Analytics also offers competent support for your research and development projects in the field of immunology. Immune Analytics is backed by the longstanding experience of the AID group in development and manufacturing of EliSpot kits, readers and analysis software. Offices and laboratories are located on the premises of the AID headquarters in the Strassberg, Germany. The pillars of our quality management system to support your drug studies are: - GLP & GCLP*-compliance of all procedures carried out in our service laboratory - Highly trained, skilled and experienced personnel - Highest patient safety by consistent sample management and maximum data integrity - Extensive assay validation and peer-review for all (experimental) procedures - GxP compliant documentation from sample receipt via reporting and data transfer to archiving - Application of validated computerized systems - Internal quality assurance by regular monitoring of all laboratory procedures (SOPs) by QA personnel - Implemented risk management - Change and deviation management (CAPA) - Open, efficient and solution-oriented communication with our customers We´re looking forward to your requests! www.immune-analytics.com +++ SARS-CoV-2 ++++ NOTE: We have developed COVID19 / SARS-CoV2 EliSpot and FluoroSpot assays to support vaccine development projects! We have also developed in vitro culture conditions to evaluate memory T cells against SARS-CoV-2 in EliSpot/FluoroSpot. Please contact us for further details! --------------------------------------------- *EMA Reflection paper for laboratories that perform the analysis or evaluation of clinical trial samples 28 February 2012 EMA/INS/GCP/532137/2010: http://www.ema.europa.eu/docs/en_GB/document_library/Reg ulatory_and_procedural_guideline/2012/05/WC500127124.pdf

4 Ebinger Straße Straßberg, BW, 72479 GermanyImmune Analytics as specialist CRO offers immunomonitoring services with a strong focus on the analysis of preclinical and clinical samples by EliSpot (enzyme-linked immuno spot) or FluoroSpot supported by a range of other methods like ELISA, flow cytometry and immune arrays. With a dedicated team of scientists, project manager and QA colleagues, Immune Analytics is specialized in the realization of projects with a high degree of assay customization. Besides the excellent scientific and technical competence, Immune Analytics adheres to international regulatory requirements of preclinical and clinical studies and is certified according to Good Laboratory Practice (GLP) and Good Clinical Laboratory Practice (GCLP). Immune Analytics also offers competent support for your research and development projects in the field of immunology. Immune Analytics is backed by the longstanding experience of the AID group in development and manufacturing of EliSpot kits, readers and analysis software. Offices and laboratories are located on the premises of the AID headquarters in the Strassberg, Germany. The pillars of our quality management system to support your drug studies are: - GLP & GCLP*-compliance of all procedures carried out in our service laboratory - Highly trained, skilled and experienced personnel - Highest patient safety by consistent sample management and maximum data integrity - Extensive assay validation and peer-review for all (experimental) procedures - GxP compliant documentation from sample receipt via reporting and data transfer to archiving - Application of validated computerized systems - Internal quality assurance by regular monitoring of all laboratory procedures (SOPs) by QA personnel - Implemented risk management - Change and deviation management (CAPA) - Open, efficient and solution-oriented communication with our customers We´re looking forward to your requests! www.immune-analytics.com +++ SARS-CoV-2 ++++ NOTE: We have developed COVID19 / SARS-CoV2 EliSpot and FluoroSpot assays to support vaccine development projects! We have also developed in vitro culture conditions to evaluate memory T cells against SARS-CoV-2 in EliSpot/FluoroSpot. Please contact us for further details! --------------------------------------------- *EMA Reflection paper for laboratories that perform the analysis or evaluation of clinical trial samples 28 February 2012 EMA/INS/GCP/532137/2010: http://www.ema.europa.eu/docs/en_GB/document_library/Reg ulatory_and_procedural_guideline/2012/05/WC500127124.pdf

Ebinger Strasser 4 Strassberg, 72479 GermanyImmune Analytics as specialist CRO offers immunomonitoring services with a strong focus on the analysis of preclinical and clinical samples by EliSpot (enzyme-linked immuno spot) or FluoroSpot supported by a range of other methods like ELISA, flow cytometry and immune arrays. With a dedicated team of scientists, project manager and QA colleagues, Immune Analytics is specialized in the realization of projects with a high degree of assay customization. Besides the excellent scientific and technical competence, Immune Analytics adheres to international regulatory requirements of preclinical and clinical studies and is certified according to Good Laboratory Practice (GLP) and Good Clinical Laboratory Practice (GCLP). Immune Analytics also offers competent support for your research and development projects in the field of immunology. Immune Analytics is backed by the longstanding experience of the AID group in development and manufacturing of EliSpot kits, readers and analysis software. Offices and laboratories are located on the premises of the AID headquarters in the Strassberg, Germany. The pillars of our quality management system to support your drug studies are: - GLP & GCLP*-compliance of all procedures carried out in our service laboratory - Highly trained, skilled and experienced personnel - Highest patient safety by consistent sample management and maximum data integrity - Extensive assay validation and peer-review for all (experimental) procedures - GxP compliant documentation from sample receipt via reporting and data transfer to archiving - Application of validated computerized systems - Internal quality assurance by regular monitoring of all laboratory procedures (SOPs) by QA personnel - Implemented risk management - Change and deviation management (CAPA) - Open, efficient and solution-oriented communication with our customers We´re looking forward to your requests! www.immune-analytics.com +++ SARS-CoV-2 ++++ NOTE: We have developed COVID19 / SARS-CoV2 EliSpot and FluoroSpot assays to support vaccine development projects! We have also developed in vitro culture conditions to evaluate memory T cells against SARS-CoV-2 in EliSpot/FluoroSpot. Please contact us for further details! --------------------------------------------- *EMA Reflection paper for laboratories that perform the analysis or evaluation of clinical trial samples 28 February 2012 EMA/INS/GCP/532137/2010: http://www.ema.europa.eu/docs/en_GB/document_library/Reg ulatory_and_procedural_guideline/2012/05/WC500127124.pdf

Lochhamer Str. 29a Martinsried, Planegg D-82152 GermanyIntana Bioscience offers interaction analysis based on a single molecule sensitive spectroscopic approach called fluorescence cross correlation spectroscopy (FCCS).

ByK-Gulden Str. 2 Konstanz, BW, 78467 GermanyIMAX Discovery is the research business unit of Axxam GmbH focused on the generation and development of novel, natural and synthetic flavour and fragrance compounds for the food and beverage, pet food, cosmetic and perfume industry. Using our strong technology platforms and expertise around taste and olfactory receptors, having access to natural and synthetic products, IMAX Discovery offers to its clients and partners support for their discovery programs. Besides that, IMAX Discovery also generates proprietary product pipelines of natural product based novel taste modulators to be partnered.

Otto-Hahn-Strasse, 15 Dortmund GermanyIMAX Discovery is the research business unit of Axxam GmbH focused on the generation and development of novel, natural and synthetic flavour and fragrance compounds for the food and beverage, pet food, cosmetic and perfume industry. Using our strong technology platforms and expertise around taste and olfactory receptors, having access to natural and synthetic products, IMAX Discovery offers to its clients and partners support for their discovery programs. Besides that, IMAX Discovery also generates proprietary product pipelines of natural product based novel taste modulators to be partnered.

88 Falkenried Building D Hamburg, HH, 20251 GermanyIndivumed offers a wide range of products to support your research and development in personalized medicine, biomarker validation, drug discovery, and companion diagnostics in the field of oncology. Indivumed offers biospecimens products, collected across all cancer types using our ISO-certified standardized protocol to ensure the highest quality product for every need: • Multi-omics grade samples: Human biospecimens e.g. FFPE, fresh frozen, matched normal tissue, plasma, PBMCs in combination with comprehensive clinical/medical data, controlled ischemia-time • Standard grade samples: Qualified External Biospecimens • Longitudinal cell-free plasma collection from oncology patients to study cDNA/ctDNA • Clinical Data Sets • Prospective collections on demand We are able to facilitate the development of personalized medicines to meet all your oncology laboratory needs with the following services: • Immunohistochemistry and fluorescent multiplex IHC (assay development, validation and prevalence analysis for preclinical and clinical studies) • Digital pathology department in-house • Spatial Transcriptomics with 10x Genomics technology • Drug profiling on cancer tissue slices • Isolation and characterization of tumor infiltrating lymphocytes • Mutation- and other genomics analysis • Proteomics • Other Customized Services

88 Falkenried Building D Hamburg, HH, 20251 GermanyIndivumed offers a wide range of products to support your research and development in personalized medicine, biomarker validation, drug discovery, and companion diagnostics in the field of oncology. Indivumed offers biospecimens products, collected across all cancer types using our ISO-certified standardized protocol to ensure the highest quality product for every need: • Multi-omics grade samples: Human biospecimens e.g. FFPE, fresh frozen, matched normal tissue, plasma, PBMCs in combination with comprehensive clinical/medical data, controlled ischemia-time • Standard grade samples: Qualified External Biospecimens • Longitudinal cell-free plasma collection from oncology patients to study cDNA/ctDNA • Clinical Data Sets • Prospective collections on demand We are able to facilitate the development of personalized medicines to meet all your oncology laboratory needs with the following services: • Immunohistochemistry and fluorescent multiplex IHC (assay development, validation and prevalence analysis for preclinical and clinical studies) • Digital pathology department in-house • Spatial Transcriptomics with 10x Genomics technology • Drug profiling on cancer tissue slices • Isolation and characterization of tumor infiltrating lymphocytes • Mutation- and other genomics analysis • Proteomics • Other Customized Services

88 Falkenried Building D Hamburg, HH, 20251 GermanyIndivumed offers a wide range of products to support your research and development in personalized medicine, biomarker validation, drug discovery, and companion diagnostics in the field of oncology. Indivumed offers biospecimens products, collected across all cancer types using our ISO-certified standardized protocol to ensure the highest quality product for every need: • Multi-omics grade samples: Human biospecimens e.g. FFPE, fresh frozen, matched normal tissue, plasma, PBMCs in combination with comprehensive clinical/medical data, controlled ischemia-time • Standard grade samples: Qualified External Biospecimens • Longitudinal cell-free plasma collection from oncology patients to study cDNA/ctDNA • Clinical Data Sets • Prospective collections on demand We are able to facilitate the development of personalized medicines to meet all your oncology laboratory needs with the following services: • Immunohistochemistry and fluorescent multiplex IHC (assay development, validation and prevalence analysis for preclinical and clinical studies) • Digital pathology department in-house • Spatial Transcriptomics with 10x Genomics technology • Drug profiling on cancer tissue slices • Isolation and characterization of tumor infiltrating lymphocytes • Mutation- and other genomics analysis • Proteomics • Other Customized Services

Inhoffenstraße 7 38124 Braunschweig GermanyInSCREENeX establishes novel mammalian cell systems that help to de-risk your drug candidate pipeline and to speed-up the drug development process. InSCREENeX's innovative product solutions (SCREENflex; CI-SCREEN) allow - establishing your desired cell test system (e.g. CHO, HEK293) within a rapid timeframe (1 month) and with unmatched expression characteristics (SCREENflex). (so far we have used it for the establishment of GPCRs, ion channels, antibodies, cytokines, retroviruses) - the generation of physiologically relevant cell lines from any mammalian primary cell type (functional immortalization - CI-SCREEN) (cell types that we have developed with this technology are e.g.: endothelial cells, epithelial cells, thyrocytes, osteoblasts, mesenchymal stem cells, chondrocytes) - the use of functionally immortalized cell lines for the development of bioassays (e.g. release assays, ADME/Tox profiling, Barrier formation/Permeability studies) On the basis of these technologies InSCREENeX offers pharmaceutical and biotech companies optimal tools to develop new drugs under in vivo conditions – adapted to in vitro set ups.

Inhoffenstraße, 7 Deutschland Braunschweig, Niedersachsen, 38124 GermanyInSCREENeX establishes novel mammalian cell systems that help to de-risk your drug candidate pipeline and to speed-up the drug development process. InSCREENeX's innovative product solutions (SCREENflex; CI-SCREEN) allow - establishing your desired cell test system (e.g. CHO, HEK293) within a rapid timeframe (1 month) and with unmatched expression characteristics (SCREENflex). (so far we have used it for the establishment of GPCRs, ion channels, antibodies, cytokines, retroviruses) - the generation of physiologically relevant cell lines from any mammalian primary cell type (functional immortalization - CI-SCREEN) (cell types that we have developed with this technology are e.g.: endothelial cells, epithelial cells, thyrocytes, osteoblasts, mesenchymal stem cells, chondrocytes) - the use of functionally immortalized cell lines for the development of bioassays (e.g. release assays, ADME/Tox profiling, Barrier formation/Permeability studies) On the basis of these technologies InSCREENeX offers pharmaceutical and biotech companies optimal tools to develop new drugs under in vivo conditions – adapted to in vitro set ups.

Rudolf-Diesel-Str. 8A Himmelstadt, D-97267 GermanyimmunoGlobe specializes in custom peptide and recombinant antibodies.

Neuendorfstr. 24a 16761 Hennigsdorf GermanyInVivo Biotech offers monoclonal antibody, recombinant protein, mammalian cell fermentation and media services.

Hennigsdorf, BB, 16761 GermanyInVivo Biotech offers monoclonal antibody, recombinant protein, mammalian cell fermentation and media services.

Lochhamer Str. 29a Martinsried/Planegg, Bavaria, 82152 GermanyIMGM Laboratories offer advanced genomic services focusing on BIOMARKER DISCOVERY, METAGENOMICS, BIODISTRIBUTION and PHARMACOGENETICS. Our broad technology portfolio includes: NEXT GENERATION SEQUENCING (Illumina MiSeq and NovaSeq), qPCR, as well as ddPCR (BioRad). Expert bioinformatics and comprehensive reporting complete our services. IMGM holds a GLP certificate and an ISO 17025 accreditation for Sanger sequencing and gene expression analysis and SNP genotyping using both real-time PCR and ddPCR. We are also certified service provider for single cell sequencing with 10x Genomics Technology for 3' Gene expression analysis and Immuneprofiling. Whether you are interested in gene expression analysis, 16S rRNA or gene panel sequencing of our other genomic services: we are looking forward to getting in touch with you. For more information please visit www.IMGM.com. Since 2019 we are part of Medicover Integrated Clinical Services (MICS) and act as their Precision Medicine Supplier.

Alter Holzhafen 19 23966 Wismar GermanyIngress-Health is a fast-growing European health-care consultancy with offices in Wismar, Germany and Rotterdam, Netherlands. We have years of experience and profound knowledge in health economics and outcomes research. Our core services focus on: • Real-World Evidence (RWE) Studies, • Strategic Market Access & Health Policy Communication, • Evidence Synthesis, and • Health-Economic Modelling. At Ingress health, we strongly believe that the future of health technology reimbursement in the EU will be based on flexible pricing systems and or provisional reimbursement with corresponding outcomes-based managed entry schemes and health economic evaluations. This belief is based on trends in digitalization of patient outcomes in clinical practice, the increasing number of drugs approved with conditional market authorization by EMA, and an increase in outcomes based managed entry schemes in the EU. This shift from reimbursement to conditional reimbursement requires a change of mindset in the industry as in the past, when developing Real-World Evidence studies, manufacturers often did not (need to) consider the health economic perspective. Ingress health team also strongly believes that a lot of products are underutilized because clinical trials did not show their value in terms of e.g. reduced side effects, improved quality of life and or compliance. Therefore, Ingress health was founded February 1st 2015. With Ingress health’s combined and integrated health economic and Real-World Evidence expertise and passion for the field, we feel that Ingress health team will be successful in optimizing your products pre and post-marketing value proposition. OUR VALUES Ingress health team is sincerely curious about our clients, the context of the project and about the product. We are thorough in everything we do. Regarding the project, we at Ingress health will consider several different angles before presenting the final result and or approach. Ingress health team is confident that we can produce high quality timely results, as such we do offer project pay per performance schemes. With Ingress health combined Real-World Evidence and health economic expertise, we are confident that we can find the unexplored value of your product.

28/3 Mörikestraße Ludwigsburg, BW, 71636 GermanyIDEXX BioAnalytics is the premier reference lab partner providing central laboratory services (Haematology, Biochemistry, Immunology, Parasitology, Microbiology, etc.) and Point of Care tests to support pharma, biotech, pet food, and academia's clinical (GCP) and preclinical veterinary studies in Europe and North America. In addition, IDEXX BioAnalytics offers expert support in toxicology Histology (GLP). IDEXX BioAnalytics provides quality veterinary research analyzers, which can also be installed to GLP standards, for preclinical and clinical research. IDEXX BioAnalytics 's team has developed nearly all the newest technologies in the field of research animal health monitoring, including all new techniques to help Replace, Reduce and Refine animal testing. IDEXX BioAnalytics provides a biological testing service for independent confirmation of quality, safety, and authenticity of biological materials.

Im Moldengraben 65 Kornwestheim, 70806 GermanyIDEXX BioAnalytics is the premier reference lab partner providing central laboratory services (Haematology, Biochemistry, Immunology, Parasitology, Microbiology, etc.) and Point of Care tests to support pharma, biotech, pet food, and academia's clinical (GCP) and preclinical veterinary studies in Europe and North America. In addition, IDEXX BioAnalytics offers expert support in toxicology Histology (GLP). IDEXX BioAnalytics provides quality veterinary research analyzers, which can also be installed to GLP standards, for preclinical and clinical research. IDEXX BioAnalytics 's team has developed nearly all the newest technologies in the field of research animal health monitoring, including all new techniques to help Replace, Reduce and Refine animal testing. IDEXX BioAnalytics provides a biological testing service for independent confirmation of quality, safety, and authenticity of biological materials.

Nicolaistr. 22 Berlin , 12247 GermanyVeterinary Diagnostic Laboratory

Altenoyther Strasse 10 Friesoythe, 26169 GermanyImmunoTools supplies antibodies, cytokines, ELISA kits, and DNA extraction kits.

Otto Hahn-Str. 15 D-44227 Dortmund GermanyIMD Natural Solutions aims to develop and commercialize groundbreaking ingredients - with a special focus on preserving agents - derived from "all" natural sources. The main target markets are in the Food & Beverages as well as the Personal Care industries.

Dortmund, NRW GermanyIMD Natural Solutions aims to develop and commercialize groundbreaking ingredients - with a special focus on preserving agents - derived from "all" natural sources. The main target markets are in the Food & Beverages as well as the Personal Care industries.

Bahnhofstraße 8 a Mainz, 55116 Germanyikfe CRO offers clinical research services including project management, clinical monitoring, data management, and clinical trial services.

Mainz, RP Germanyikfe CRO offers clinical research services including project management, clinical monitoring, data management, and clinical trial services.

Adalbert-Zoellner-Str. 1 Marktredwitz, 95615 GermanyIris Biotech provides scientists in both industry and academia with innovative and rare compounds, while also being your reliable partner for a comprehensive supply of standard consumables. Guided by our dedication to deliver competent service as well as the highest quality to our customers, our company’s focus remains Peptide Chemistry, while we also have strong expertise in Drug Delivery, Life Sciences, and Linkerology. Due to the growing demand for tailor-made compounds and solutions, we further increased our Custom Synthesis capabilities in 2013. Our skilled scientists and technicians offer profound expertise in the custom manufacturing of both simple and complex molecules.

IRIS Biotech GmbH Waldershofer Str. 49-51, D-95615 Marktredwitz, GermanyIris Biotech provides scientists in both industry and academia with innovative and rare compounds, while also being your reliable partner for a comprehensive supply of standard consumables. Guided by our dedication to deliver competent service as well as the highest quality to our customers, our company’s focus remains Peptide Chemistry, while we also have strong expertise in Drug Delivery, Life Sciences, and Linkerology. Due to the growing demand for tailor-made compounds and solutions, we further increased our Custom Synthesis capabilities in 2013. Our skilled scientists and technicians offer profound expertise in the custom manufacturing of both simple and complex molecules.

Paul-Ehrlich-Straße 19 Nürnberg-Heroldsberg, 90562 GermanyInstitute for Biomedical and Pharmaceutical Research (IBMP) offers bioanalysis, bioavailability and pharmacokinetic studies.

35 Bölschestraße Berlin, Berlin, 12587 GermanyICRC-Weyer is an established all-phase contract research organization (CRO) based in Berlin, Germany. The company was founded by Prof. Dr. Geerd Weyer and offers services ranging from pre-clinical through to phase IV clinical trials. We provide complete turnkey solutions including data management, monitoring and medical review services for all stages of the clinical development process.

Pfaffplatz 10 D-67655 KaiserslauternSince our founding in 1997, we focus the Institute of Immunology and Genetics Kaiserslautern on highly specialized areas of immunological, molecular biology and human genetic diagnostics. Our institute is a successful and independently on the market operating company. CUSTOMER / CLIENT Our clients include universities, specialized treatment centers and specialized medical practices, clinics, research institutes, companies of pharmaceutical research, stem cell donor organizations, as well as in the context of paternity tests courts and youth welfare offices of Rheinland-Pfalz. The Institute is the professional association of EUROTRANSPLANT laboratories and is in the NMDP registered (US National Marrow donor Program) for the diagnosis before stem cell transplantation and approved.

10 Pfaffplatz Kaiserslautern, RP, 67655 GermanySince our founding in 1997, we focus the Institute of Immunology and Genetics Kaiserslautern on highly specialized areas of immunological, molecular biology and human genetic diagnostics. Our institute is a successful and independently on the market operating company. CUSTOMER / CLIENT Our clients include universities, specialized treatment centers and specialized medical practices, clinics, research institutes, companies of pharmaceutical research, stem cell donor organizations, as well as in the context of paternity tests courts and youth welfare offices of Rheinland-Pfalz. The Institute is the professional association of EUROTRANSPLANT laboratories and is in the NMDP registered (US National Marrow donor Program) for the diagnosis before stem cell transplantation and approved.

Flughafenstrasse 52a D-22335 Hamburg GermanyIBL International offers reagents, antibodies, and assay kit products for purchase.

Bioparc 3, 850 boulevard Sébastien Brant Illkirch-Graffenstaden, F-67400 FranceInoviem Scientific is a CRO providing a range of services from discovery to clinical trials. We help pharmaceutical R&D meet its challenges and best address patient issues through our comprehensive range of services and patient-centric approach. Whether your projects are linked to the establishment of relevant cellular models, biophysics and biology assays, drug discovery, biosafety or cohort stratification, Inoviem adapts its organization to your project. We know that every customer is unique and each project is different that’s why our teams are very attentive to proposing relevant solutions suitable to your needs. One of our strengths? Working directly on non-modified human tissue. From the beginning, we consider the natural environment in which a drug will have its beneficial effect to provide you with critical data that will secure your development strategy.

Wiesbaden, GermanyINVITRO-CONNECT offers REACH analysis, in vitro assays, and physical chemical analysis services. INVITRO-CONNECT GmbH is the 1. independent Provider of Laboratory Services cooperating with a network of over 80 test laboratories and service providers for the Pharmaceutical, Chemical, Cosmetic and Medical Device Industry and connecting laboratory services with professional customer support such as tests and analyses for most cost-effective price-performance ratio.

Friedrich-Bergius-Ring 15 D-97076 Würzburg, GermanyInnoChemie offers custom synthesis, compound separation and purification services.

Würzburg, BY GermanyInnoChemie offers custom synthesis, compound separation and purification services.

Max-Planck-Straße 6 - P.O. Box 1143 Holzminden, 37603 GermanyInstitute Dr. Schrader offers efficacy testing, safety testing, and in vitro studies on human skin models and cell cultures.

Institut für Produktqualität GmbH Wagner-Régeny-Str. 8 12489 Berlin • GERMANYifp Institut für Produktqualität is an independent and neutral laboratory and competence centre for modern food, feed and pharma analytics. The Berlin-based institute is involved in numerous research projects, and develops and produces innovative diagnostic products for use in public and industrial laboratories. Cooperations with companies such as QIAGEN, for instance, allow users all over the world to benefit from ifp's expertise in the field of food analytics and kit development.

8 Wagner-Régeny-Straße Berlin, Berlin, 12489 Germanyifp Institut für Produktqualität is an independent and neutral laboratory and competence centre for modern food, feed and pharma analytics. The Berlin-based institute is involved in numerous research projects, and develops and produces innovative diagnostic products for use in public and industrial laboratories. Cooperations with companies such as QIAGEN, for instance, allow users all over the world to benefit from ifp's expertise in the field of food analytics and kit development.

3 Hedwig-Laudien-Ring Hedwig-Laudien-Ring 3 Ludwigshafen am Rhein, RP, 67071 GermanyThe Institut Kuhlmann was founded by Fritz Kuhlmann in 1970 as an autonomous, independent contract laboratory. No other companies or institutions are involved. In 2003, the Institut Kuhlmann moved into modern laboratory premises. The laboratory provides 1200 m² of space and is equipped with the latest analytical instrumentation, information and communications technology. Our Team Our team consists of 55 employees, including 9 chemists with Ph.D. and another 12 chemists with advanced degrees (M.S./diploma). Our Strengths We address customer-specific analytical questions using sophisticated analytical methodology. In the process, we constantly develop and validate new analytical methods, or adapt existing methods to meet specific customers’ requirements.

Am Pharmapark Dessau-Roßlau, Saxony Anhalt, 06861 GermanyIDT Biologika offers process development and GMP compliant manufacturing of Viral Vaccines, Oncolytic Viruses, Gene and Immunotherapeutics as well as Biologics in its facilities in Germany and US. With decades of experience in the commercial production of live viral BSL2 vaccines and fill/finish of biologics at our FDA and EMA approved sites (ANVISA ready), IDT Biologika handles every step in process development, manufacturing, quality control and packaging processes. We strive for a strong collaboration with our client partners to support the development of their vaccines and other biopharmaceuticals.

19 In den Leppsteinswiesen Roßdorf, HE, 64380 GermanyICCR-Roßdorf GmbH provides a range of standard research models to the pharmaceutical and biotechnology industries, government, academia and other life science organizations.

Arheilger Weg 17 Roßdorf, 64380 Germanyibacon is an independent contract research institute serving the global chemical and pharmaceutical industry. We are providing studies in laboratory and field that are required for the registration and approval of Plant Protection Products Chemicals/REACh Biocides Pharmaceuticals Veterinary medicines Our testing facility is certified as conforming to Good Laboratory Practice (GLP) standards and offers a wide range of aquatic and terrestrial ecotoxicology studies, physical and chemical parameter characterization, residue analysis and environmental fate studies. All studies are performed in accordance with international accepted guidelines.

Köpenicker Str. 325 Haus 12, Modul C Berlin, 12555 GermanyGIANT labs offers you a worldwide unique portfolio of analytics for the characterization of unknown materials. Simply, quickly and fully automatically determine the chemical composition of organic, inorganic and metallic particles with the GIANT labs analysis system and methods. A team of experts with years of experience in microscopic spectroscopy makes it possible to analyze not only individual particles but also thousands of microparticles at minimal cost and time.

Koepenicker Str. 325 Haus 12 Berlin, 12555 GermanyGIANT labs offers you a worldwide unique portfolio of analytics for the characterization of unknown materials. Simply, quickly and fully automatically determine the chemical composition of organic, inorganic and metallic particles with the GIANT labs analysis system and methods. A team of experts with years of experience in microscopic spectroscopy makes it possible to analyze not only individual particles but also thousands of microparticles at minimal cost and time.

Volmerstr. 5 Berlin, 12489 GermanyJPT is an ISO 9001:2015 certified provider of innovative peptide products and services and a partner for research projects focusing on the development of novel immune therapeutics & diagnostics, profiling of various enzyme classes and proteomics. JPT has developed a portfolio of proprietary technologies and a series of unique products which support a worldwide customer base. Since 2011 all catalog products such as peptide microarrays & peptide pools are avalaible through an online shop.

71 Löbstedter Straße Jena, Thüringen, 07749 GermanyJena Bioscience is life science reagent and custom synthesis provider, specializing in nucleoside and nucleotide synthesis. Also available: molecular biology reagents, protein crystallization tools, probes & epigenetics products, click chemistry reagents as well as affinity chromatography and protein expression products.

Münsterstraße. 248Jubilant Clinsys provides Phase I-IV clinical support and regulatory services.

1 Langenbeckstraße Mainz, RP, 55131 Germany

Obergasse 4 Volxheim, Germany, 55546 GermanyCustom Synthesis

JenLab GmbH Science Park 2 Campus D1.2 66123 Saarbrücken

c/o CoLaborator, S141 Müllerstraße 178 Berlin, Berlin, 13353 GermanyAssay Engineers is a fast-growing specialty CRO company focusing on hyperplex bioanalysis. We support precision medicine through translational biomarker services ranging from biomarker identification through validation and patient stratification. Based on a concise description of the biomarker's specified use (COU) we help selecting the appropriate bioanalysis platform using a fit-for-purpose approach.

Kiebitzhörne 19 Ovelgönne, 26939 GermanyAssay Engineers is a fast-growing specialty CRO company focusing on hyperplex bioanalysis. We support precision medicine through translational biomarker services ranging from biomarker identification through validation and patient stratification. Based on a concise description of the biomarker's specified use (COU) we help selecting the appropriate bioanalysis platform using a fit-for-purpose approach.

Geyerspergerstr. 27 Munich D-80689 GermanyKlifovet provides efficacy studies, field safety studies, paltability studies, statistics, and medical writing.

22 Skovvej Kruså, 6340 DenmarkKinase Logistics is the official agent for Carna Biosciences in Europe. Kinase Logistics offers - recombinant protein kinases - recombinant lipid kinases kinases - kinase assay kits - biochemical kinase profiling and screening - cellular kinase profiling and screening

FB Med., Goethe-Universität, Zentrale Forschungseinrichtung, Haus 67, Theodor-Stern-Kai 7 Frankfurt am Main, Hessen, 60590 GermanyTesting of compounds, formulations and devices for the intervention of sleep apnea in large animal models (pig). Testings for other indications are also possible.

Schallbruch 1 D-42781 Haan GermanyKohne Pharma provides pharmaceutical dossiers and regulatory affairs consulting.

Hornussstr. 16 D-79108 Freiburg, GermanyKOEHLER eClinical is the successor company which was formed by the merger of Dr. Manfred Koehler GmbH Pharma Biometrics Consulting and its affiliated company clinIT AG, specialized in EDC solutions. Having started as a company specialized in data management, biostatistics and EDC solutions we have broadened our core portfolio with full-service clinical projects. Our innovative concepts and a well-proven network of monitors and regional partner CROs allow us to conduct global projects without being a global CRO. Being one of the pioneer companies who developed and applied an EDC application for collecting and managing clinical data, we utilize our user-friendly, intuitive and flexible tool to optimize the data collection and management process. Unlike EDC providers who offer solely a standard product, we offer our customers a possibility to develop unique customized features according to their requirements. Quality of service is our top priority and is guaranteed by the extensively trained and highly qualified team and confirmed by regular external and internal audits. Our company is ISO 9001:2008 certified. We are proud to be an employee-oriented, family-friendly company with a dedicated team and low staff turnover.

Max-Becker-Str. 6 76356 Weingarten / Baden GermanyKLOCKE Gruppe offers complete range of services for contract manufacturing and contract packaging.

20A, rue du Général Leclerc Plobsheim, 67115 FranceKaLy-Cell provides plateable cryopreserved human and animal including human hepatocytes metabolically characterized and qualified for induction, for high content assays and for long-term toxicity assays. KaLy-Cell also provides services in in vitro toxicicty and induction tests.

2 Erzwäsche Salzgitter, NDS, 38229 GermanyKirsch Pharma provides pharmaceutical raw materials and innovative solutions for the optimisation of manufacturing processes.

2A Lindwurmstraße, München, BY 80337, DEThe clinics and institutes of the Clinic of the University of Munich are centers of excellence in medical research and occupy a prominent position nationally and internationally. In addition to their high commitment to the care of the patients, the doctors at the clinic are intensively engaged in research, with the aim of better understanding the diseases, progress in diagnostics and therapy, and ultimately defeating them. This often happens in interdisciplinary, national and international cooperation. From basic research to clinical application at the patient bed - at one of the most profound research locations in Germany, this is an established practice. The clinical research facilities of the clinic and the institutes of the medical faculty complement each other in an ideal way. Nearly 62 million euros of inoculated research resources are proof of the high reputation of medical research at LMU Munich.

15 Marchioninistraße, München, BY 81377, DEThe clinics and institutes of the Clinic of the University of Munich are centers of excellence in medical research and occupy a prominent position nationally and internationally. In addition to their high commitment to the care of the patients, the doctors at the clinic are intensively engaged in research, with the aim of better understanding the diseases, progress in diagnostics and therapy, and ultimately defeating them. This often happens in interdisciplinary, national and international cooperation. From basic research to clinical application at the patient bed - at one of the most profound research locations in Germany, this is an established practice. The clinical research facilities of the clinic and the institutes of the medical faculty complement each other in an ideal way. Nearly 62 million euros of inoculated research resources are proof of the high reputation of medical research at LMU Munich.

Am Klopferspitz 19a Martinsried D-82152 GermanyKINAXO Biotechnologies provides drug profiling design, affinity-based separation, and data processing.

Planegg, BY, 82152 GermanyKINAXO Biotechnologies provides drug profiling design, affinity-based separation, and data processing.

Raiffeisenstr. 4 40764 Langenfeld GermanyLabtec provides transdermal systems, dissolvable films as well as contract development and manufacturing.

Rathenaustrasse 54 63263 Neu-IsenburgLorenz Snack-World is a growth-oriented European brand-name company with an international focus. Headquartered in Neu-Isenburg (near Frankfurt), Germany, with production sites and sales organisations in Germany, Poland, Austria and Russia, the company exports to around 80 countries throughout the world – spread as far and wide as New Zealand, New Caledonia and Greenland. Lorenz Group employs more than 2.900 people. Our company has been family-run for four generations. The responsibility for employees and customers has been passed on from generation to generation. Therefore, we are committed to maintaining a long-term view, reliability, sustainability and partnership with our employees, customers and suppliers. We have always made excellent products in four main categories: chips, extruders, salty bakery and nuts. With our crunchy, tasty products we make lifes of people more relaxing, more exciting, more entertaining, more fun, in short term: we make life more beautiful!

59 Pascalstraße Aachen, NRW, 52076 GermanyWe Are Phenotyping! Providing an understanding of significant biotic problems by extracting and quantifying data from biological images LemnaTec’s goal is to quantify human vision on organisms. Whatever images we take for whatever purposes: The first step will always be to generate reproducible and scientifically sound images in a wide range of light wavelengths – mostly going far beyond human vision. All phenotyping results are stored and analysed automatically. Images can be analysed and re-analysed in an unlimited number of ways, generating image-derived values for a huge amount of quantitative parameters according to varying interests and needs. LemnaTec is the Global Leader in Plant Phenomics Science testing is all about effect monitoring and quantification. Depending on the aim of the test design and data analysis, evaluations vary widely and help to generate new information. Our Scanalyzer Plant Phenomics Platform is designed to link Genotype and Phenotype information in the field of High Throughput Plant Phenotyping High Content Plant Phenomics Root and shoot Phenotyping Infield Phenotyping High precision Plant Phenotyping in Growth Chambers In ecotoxicology deviations from control growth or control behaviour are interpreted as toxic effects. In similar experiements with different objectives the results of nematode, cell culture or fish embryo testing may identify new active ingredients for human or animal care products. In plant protection the screening of aphid, fungi and plant or animal growth inhibition or growth stimulation leads to the detection of new substances for the protection of future crops. Plant phenotyping helps to identify particular gene functions by the description of specific growth patterns under stress conditions, which then in turn become key elements in plant breeding. LemnaTec develops imaging units, image analysis automatisation and data handling strategies that fit all these varied needs of research and production to help our customers to design and develop products suitable to meet future challenges.

Emil-Figge-Straße 76aLead Discovery Center provides expertise and partnerships in organic synthesis, assay development, biochemical and cellular assays, screening, ADME profiling, and compound profiling services.

Rosenbergstraße 85 Stuttgart, 70193 Germany

Sonnenstraße 16LMU Munich ReproZentrum focuses on veterinary research and offers in patient and out patient services.

Oberschleißheim, BY GermanyLMU Munich ReproZentrum focuses on veterinary research and offers in patient and out patient services.

Gerhart-Hauptmann-Strasse 48 Dossenheim, 69221 GermanyLOXO supplies reagents for diagnostic analysis including antibodies, ELISA, lysates, proteins, and substrates.

2327 Jägerstraße Oldenburg, NDS, 26121 GermanyLUFA Nord-West is affiliated with the Chamber of Agriculture in Lower Saxony and an accredited service laboratory. The wide range of analyses offered reflects the dimensions of our portfolio which is mastered by no less than five individual institutions. These are based in the German towns of Hamelin and Oldenburg.

Lise-Meitner-Str. 25-29 24223 Schwentinental GermanyLKF is a central laboratory dedicated to medical-analytical services in international clinical trials. Our stringent quality management system is based on the GCP and accredited to ISO 17025. This ensures an excellent quality performance and enables us to prove the quality required for clinical trials at any time. Analytical quality is regularly certified by participation in proficiency testing programs, e.g. NGSP for HbA1c (Level I Certificate ) or INSTAND e.V.

29 Lise-Meitner-Straße Schwentinental, SH, 24223 GermanyLKF is a central laboratory dedicated to medical-analytical services in international clinical trials. Our stringent quality management system is based on the GCP and accredited to ISO 17025. This ensures an excellent quality performance and enables us to prove the quality required for clinical trials at any time. Analytical quality is regularly certified by participation in proficiency testing programs, e.g. NGSP for HbA1c (Level I Certificate ) or INSTAND e.V.

Nicolaistrasse 22, 12247 Berlin, GermanyLabConnect is the preeminent provider of central laboratory support services for logistically and analytically complex studies. LabConnect offers clinical chemistry, DNA sequencing, nucleic acid extraction, genotyping, flow cytometry, pharmacology, and toxicology services.

Am Förderturm 9 Castrop-Rauxel, 44575 GermanyLohmann Research Equipment distributes high quality products for biomedical research in Europe including multielectrode recordings systems, automated screening equipment, or human electrophysiological recording devices used for neuronavigation during neurosurgery. Contract services include cDNA/mRNA expression and electrophysiology studies.

Castrop-Rauxel, NRW GermanyLohmann Research Equipment distributes high quality products for biomedical research in Europe including multielectrode recordings systems, automated screening equipment, or human electrophysiological recording devices used for neuronavigation during neurosurgery. Contract services include cDNA/mRNA expression and electrophysiology studies.

Katzbergstr. 1 40764 Langenfeld GermanyWe are selling & trading partner of the LANXESS Group for chemical intermediates and specialties. We offer products for the chemical industry, cosmetics, animal feed and selected plant treatment products. Our international customers appreciate our comprehensive and uncomplicated service. Our sales force and our technical marketing advice you competent and practice-oriented. Your regional contact person , as well as the entire LD team, are available and ensure close cooperation.

Otto-Hahn-Strasse 13 79395 Neuenburg GermanyLosan Pharma develops and manufactures solid oral dosage forms.

Neuenbürg, BW, 75305 GermanyLosan Pharma develops and manufactures solid oral dosage forms.

Am Haag 4LAT provides contract services in  routine analysis, stability testing, validation, chromatographic separation, and chemical-pharmaceutical analysis.

Hermann-Herder-Str. 7Logopharm provides antibodies and spectroscopy services.

Schlossstraße 14 D-79232 March, GermanyLogopharm provides antibodies and spectroscopy services.

11 Badstraße Weikersheim, BW, 97990 GermanyLa Merie Publishing is an independent business information provider for the biotechnology and pharmaceutical industry. La Merie Publishing prepares brief and full reports as well as competitor analysis reports and target pipeline lists, the latter two in a tabulated format with structured listings of industry-relevant data. La Merie Publishing products can be purchased in our new online store at www.lamerie.com and at selected Resellers. The focus of our products is directed towards therapeutic biologics, such as antibodies, proteins, peptides, vaccines and gene & cell therapy. We pay special attention to biosimilar antibodies and proteins, antibody drug conjugates, bispecific antibodies, TCR & CAR engineered antibodies, mRNA vaccines & therapeutics, oncolytic viruses and immuno-oncology in general. To leverage our expertise and knowledge accumulated in our in-house database, we offer custom report preparation services for corporate clients, including, but not limited to, pipeline analysis reports, drug profiles and any other competitive intelligence elaboration of interest for our clients.

Lebensmittelanalytik Geesthacht, 21502 GermanyWe provide management and medical services in private and hospital laboratories since 1945. The LADR network is composed of regional laboratories all over Germany. Approximately over 3,000 employees work in our 16 reference laboratories, 34 basic and routine laboratories, and 31 hospital laboratories. We serve more than 20,000 private physicians and more than 370 hospitals. We perform more than 11,000 different test methods in anatomical pathology, clinical chemistry, coagulation, cytology, drug-monitoring, endocrinology, environmental medicine, food testing, hematology, human genetics, hygiene, immunology, infectious disease serology, microbiology, molecular biology, molecular genetics, oncology, paternity testing, toxicology, veterinary medicine, and (waste) water-/soil testing​. Annually we receive approximately 5 million requests or 19 million tests in our reference laboratories and 9 million requests or 60 million tests in our routine laboratories. The turn-around-time of non-microbiological requests is: within the same day for 70 %, within 24 hrs for 90 %, and within 1 week for more than 99 %. Together with our logistics partner ISG Intermed Service GmbH & Co. KG we serve daily 660 permanent routes and 15,000 private physicians. Intermed`s mail and parcel services guarantee nationwide 24-hour delivery.

Leonhardsweg 2 Unterhaching, Bayern, 82008 GermanyLife Chemicals is a major producer and supplier of HTS compounds and a well-recognized provider of custom synthesis and computational chemistry services to pharmaceutical, biotech, crop science companies, and academic institutions across the globe. Developing its business development Life Chemicals has associated and headquartered a family of R&D chemical companies, namely I.F. Lab, Spoluka, Life Chemicals Inc., Life Chemicals USA (Woodbridge, CT), and Life Chemicals Europe (Munich, Germany), to operate as an integral whole where every single company is focused on its individual range of products and services and, at the same time, all are motivated by achieving their common goal. Today Life Chemicals is a fully integrated platform for early drug discovery, providing complete range of contract research and contract manufacturing services. Our broad experience in synthetic organic chemistry and up-to-date equipment ensure high quality services in custom synthesis of drug-like compounds and advanced Building Blocks in mg to multiKG quantities, design and synthesis of combinatorial libraries, route scouting and production scale-up. Our expertise in computational chemistry and employment of versatile in silico techniques, such as similarity and pharmacophore search, molecular descriptors analysis, docking screening and protein modeling, enable careful design of Fragment collections, Targeted and Focused libraries and customized sets of compounds. Our keen understanding of drug discovery process with computer-assisted approaches, our knowledge of medicinal chemistry and our solid scientific background supported with a powerful production infrastructure allow us to provide efficient solutions for R&D programs of our customers, including hit-to-lead and lead optimization, improvement of drug potency, selectivity and ADMET, development of QSAR models and medchem design.

Tatzberg 47 Dresden, 01307 GermanyLipotype combines cutting-edge lipidomics technology with decades of leading lipid research expertise to deliver you convincing lipidomics results. Lipotype Lipidomics provides you with easy access to lipids and lipid metabolism data for more than 4200 individual lipids – the broadest lipidomics coverage available. Our mass spectrometry-based lipidomics platform can be applied to all biological samples. Lipotype Lipidomics is robust and reproducible, and combines reliable data quality control with state-of-the-art data visualization and statistical analyses. Lipotype translates your complex lipidomics data sets into convincing lipidomics results, in as little as two weeks. Lipotype is the leading lipidomics service provider and serves all scientists from around the world. Contact our research project support, order your lipidomics services, send in your samples, and quickly understand your lipidomics results. RESEARCH APPLICATIONS Lipidomics for Biotech, Pharma & Clinical Research Cancer Systems Biology, Cerebrospinal Fluid Analysis, Compound Distribution, Compound Integrity, Drug Distribution Studies, General Toxicology, In Vitro Efficacy Test, In Vivo Pharmacokinetics, Metabolic Stability, Pharmacodynamic Biomarkers Discovery, Phenotypic Drug Discovery (PDD) Strategies, PK PD Modeling & Analysis, Plasma Stability Assay, Quality Control, Release Testing, Safety Pharmacology, Systems Pharmacology, Target Identification, Target Validation, Tissue Cross Reactivity, Toxicokinetic Analysis Lipidomics for Dermatology & Cosmetics Dermal Toxicology, Dermatology Models, In Vitro Skin Models, Moisturization, Sebum Production, Skin Permeability, Transepidermal Water Loss Lipidomics for Biomarkers Biomarker Analytical Validation, Biomarker Clinical Validation, Biomarker Discovery, Biomarker Services, Clinical Biomarkers, Clinical Trial Studies: Biomarkers, Diagnostic Biomarkers Discovery, Molecular Markers, Pharmacodynamic Biomarkers Discovery, Predictive Biomarkers Discovery, Prognostic Biomarkers Discovery Lipidomics for Metabolism Analysis Basic Metabolic Profiling, Cell Membrane Lipidomics, Fatty Acid Profiling, Lipid Detection, Lipid Profiling, Metabolic Stability, Metabolite Identification, Metabolite Identification and Profiling, Metabolite Quantification, Metabolomics, Metabonomics Analysis, Molecular Profiling, Multi-Omics Study Lipidomics for Food & Agriculture Dairy Testing, Herd Productivity, Metabolism Studies in the Edible Tissues, Milk and Dairy Nutrition, Oilseed Quality Testing, Product Properties, Quality Control OUR SOLUTION Lipotype Lipidomics is the worldwide leading lipid analysis service technology. The broadest coverage of lipids From storage lipids to membrane lipids and signaling lipids, Lipotype Lipidomics offers the broadest coverage of lipids. Our lipid analysis services identify and quantify 85+ lipid classes, in total more than 4200 individual lipids. We can work with all samples From organelles, bacteria, yeast, and other microbes to animal cells, skin tapes, body fluids, blood and plasma, tissues and organs (liver, brain, etc.), oils, milk, and far more - our lipidomics services can be applied to all biological samples. Minimal sample amounts Our mass spectrometry-based Lipotype Lipidomics technology requires only minimal sample amounts per lipid analysis. For example: our lipidomics platform can perform measurements of 1 µL of blood plasma. Get your results fast We have developed a high throughput workflow for thousands of samples per week. Our lipid analysis automation increases reproducibility and offers you to get your lipidomics reports in as little as 2 weeks. Lipidomics for all scientists Our lipidomics services are offered in 55+ countries. Lipotype Lipidomics makes lipid analysis easy and convenient for all scientists. OUR EXPERTISE A unique team of biologists, biochemists, MS development specialists, and data scientists. Reliable data quality control Lipotype Lipidomics is robust, reproducible, and GMP certified. We use internal standards in every sample, and can quickly detect sample collection and storage related quality issues. Lipidomics and lipids expertise Lipotype Lipidomics leverages decades of lipids biology expertise from esteemed academic institutions (EMBL, Max-Planck, etc.), industry and medical research. We continue to develop our technology further to provide you the best lipidomics. YOUR RESULTS Our lipidomics data analysis reports help you understand complex lipidomics data sets. Standard Report The standard report contains your quantitative analysis data (pmol and mol% data for every sample), graphs about the analysis quality, a lipid class profile, and a standard principal component analysis. Extended Report & LipotypeZoom The extended report contains further go-to lipidomics data analyses and figures, and encompasses an ANOVA test to quickly show you what part of your lipidomics data is specifically interesting. The extended report also comes with LipotypeZoom, a lipidomics data exploration tool. Use LipotypeZoom to curate and download your data. Make your data fit your research question! Statistical Report Our statistical report contains custom statistical tests to answer your questions. Cohort comparisons, correlation analyses, feature and pathway enrichment analyses – you name it, we do it for you. HOW WE WORK Order your lipidomics. Send in your samples. Receive your results. 1. Contact us! 2. Receive consultation, the sample preparation guideline, and your quote. 3. Prepare your samples and send them in. 4. We extract the lipids, then identify and quantify them. 5. We generate your data, reports, and statistics, and send them to you.

Louis Pasteur Str. 30 Luckenwalde, 14943 GermanyATCC is a trusted and innovative global partner for high-quality authentic biomaterials, standards, and services. They are one of the world’s largest and most diverse resource centres providing human and animal cell lines, as well as molecular genomic tools, bacteria, viruses, protists, fungi, and biological reagents. LGC's partnership with ATCC facilitates the exclusive distribution of this extensive collection to Life Science researchers throughout Europe and Africa.

Louis-Pasteur-Str. 30 Luckenwalde, 14943 GermanyATCC is a trusted and innovative global partner for high-quality authentic biomaterials, standards, and services. They are one of the world’s largest and most diverse resource centres providing human and animal cell lines, as well as molecular genomic tools, bacteria, viruses, protists, fungi, and biological reagents. LGC's partnership with ATCC facilitates the exclusive distribution of this extensive collection to Life Science researchers throughout Europe and Africa.

Mercastorstrasse 51 Wesel, 46485 GermanyATCC is a trusted and innovative global partner for high-quality authentic biomaterials, standards, and services. They are one of the world’s largest and most diverse resource centres providing human and animal cell lines, as well as molecular genomic tools, bacteria, viruses, protists, fungi, and biological reagents. LGC's partnership with ATCC facilitates the exclusive distribution of this extensive collection to Life Science researchers throughout Europe and Africa.

Berlin, Berlin GermanyLeibniz-Institut für Mol. Pharmakologie provides fluorescence services, molecular characterization, and in silico screening.

1 Dr.-Pauling-Straße Bruckberg, BY, 84079 GermanyThe AGROLAB GROUP is a Europe-wide laboratory group with approximately 1,200 employees in 20 offices. We offer analysis in the fields of agriculture, environment, water and food. There we must European value leader call. Customers appreciate our reliable, fast analysis and our excellent service.

Falkenberger Str. 4 D-09600 Niederschöna GermanyLaboTest provides high throughput screening compounds, building blocks, intermediates, and environmental chemicals.

Oberhafen Straße 1 20097 Hamburg GermanyLöns Pharma manufactures pharmaceuticals, medical devices, cosmetics and dietary supplements.

Robert-Rössle-Str. 10, B55 Berlin, Germany, 13125 Germany

Nattermannallee 1, Cologne, 50829 GermanyLonza provides advanced cell biology and cell engineering solutions that support customers from discovery to the clinic. We provide primary human cells, specialized media, advanced cell culture and transfection tools, supported by best-in-class quality, regulatory and scientific support. We support customers from basic research through preclinical and process development stages of small molecules, biologics, and cell and gene therapy programs in drug discovery and immuno-oncology. This includes immunogenicity prediction and assessment, manufacturability risk assessment and protein re-engineering.

Klarastraße 66, D-79106 Freiburg, GermanyLabor fur DNA-Analytik provides DNA services and hybridization.

Rheinstr. 17BAt LAROVA, we produce pivotal PCR reagents such as deoxyribonucleotides (dNTPs), ribonucleotides (NTPs), and polymerases. To ensure a consistent level of quality, we operate under the international standards ISO 9001:2015 and ISO 14001:2015.

Löbstedter Str. 80 Jena, Thueringen, 07749 GermanyAt LAROVA, we produce pivotal PCR reagents such as deoxyribonucleotides (dNTPs), ribonucleotides (NTPs), and polymerases. To ensure a consistent level of quality, we operate under the international standards ISO 9001:2015 and ISO 14001:2015.

Lohmannstraße 2LTS Lohmann Therapy Systems supplies transdermal and oral systems.

Königinstr. 16 80539 Munich GermanyLudwig Maximilian University of Munich - Department of Pharmacology, Toxicology and Pharmacy supports veterinarians in toxicological analyses regarding diagnosis and therapeutic measurements.

Geschwister-Scholl-Platz 1 München, 80539 GermanyLudwig Maximilian University of Munich - Department of Pharmacology, Toxicology and Pharmacy supports veterinarians in toxicological analyses regarding diagnosis and therapeutic measurements.

L4-QLeiden University Medical Center offers research services in the fields of malaria, cellular immunology, glycobiology, and epidemiology.

5 Ickstattstraße, München, BY 80469, DEWith over 15 years of experience in clinical studies we offer a high level of know how to our customers. In addition to our services in clinical trials we are conducting workshops for the animal health industry (by Forum Institute for Management). Once a year we are offering internships for young veterinarians in collaboration with Hardenberg Consultants.

Venusberg-Campus 1, Bldg 76 Bonn, NRW, 53127 GermanyLIFE & BRAIN is a biomedical enterprise and commercial hub of the University of Bonn Medical center. LIFE & BRAIN was founded in 2002 and is located at the University Hospital Campus in Bonn, Germany. As a center of innovation, LIFE & BRAIN acts as a revolving door between academic research and industry. Innovative research results are recognized early and developed further into marketable biomedical products and services. Scientific excellence, market-oriented translational research and plans for spinoffs grow together in a network structure supported by creative external collaborations. Integrating a unique set of expertise in Cellomics, Genomics and NeuroCognition research LIFE & BRAIN aims at delivering the next generation of products for disease modeling and prediction, compound development and tissue regeneration. The combination of technological know-how and scientific excellence makes LIFE & BRAIN the perfect partner for academic and commercial research. Life & Brain offers NeuroImaging services, stem cell reporgramming, Nucleic acid extraction, SNP-genotyping, methylation analysis, molecular karyotyping and PacBio long-read sequencing.

Venusberg-Campus 1, Bldg 76 Bonn, NRW, 53127 GermanyLIFE & BRAIN is a biomedical enterprise and commercial hub of the University of Bonn Medical center. LIFE & BRAIN was founded in 2002 and is located at the University Hospital Campus in Bonn, Germany. As a center of innovation, LIFE & BRAIN acts as a revolving door between academic research and industry. Innovative research results are recognized early and developed further into marketable biomedical products and services. Scientific excellence, market-oriented translational research and plans for spinoffs grow together in a network structure supported by creative external collaborations. Integrating a unique set of expertise in Cellomics, Genomics and NeuroCognition research LIFE & BRAIN aims at delivering the next generation of products for disease modeling and prediction, compound development and tissue regeneration. The combination of technological know-how and scientific excellence makes LIFE & BRAIN the perfect partner for academic and commercial research. Life & Brain offers NeuroImaging services, stem cell reporgramming, Nucleic acid extraction, SNP-genotyping, methylation analysis, molecular karyotyping and PacBio long-read sequencing.

Ostendstr. 25 Berlin, 12459 GermanyLGC is a global manufacturer and distributor of high-quality certified reference materials, research chemicals (TRC), genomics solutions, proficiency testing, and analytical testing services. We employ our 180 years of scientific heritage, cutting-edge expertise in measurement science and track record of innovation to progress research & development and improve outcomes across pharmaceuticals, diagnostics, food, environment, industry and consumer products. Our products and services stand out, producing to the highest quality, continually adapting to changing regulation, and providing expert support and documentation to help ensure the accuracy of your analytical results. LGC. Science for a safer world. We serve as the UK’s National Measurement Institute for chemical and bioanalytical measurements. Meet our brands: - TRC TRC offers 150,000+ research chemicals, with a large inventory readily available globally. Discover our wide range of bioactive small molecules, stable isotope labelled & controlled substances to advance your research. - AXIO Proficiency Testing AXIO Proficiency Testing is a global provider of proficiency testing schemes. We support over 13,000 laboratories, with over 2,700 proficiency tests, in over 165 countries worldwide, to meet their regulatory and accreditation requirements. - Dr Ehrenstorfer Dr Ehrenstorfer provides a comprehensive range of high-quality reference materials. Over 50% of the portfolio is accredited to ISO 17034, with 14,000+ reference materials available. - LGC Industrial LGC Industrial offers innovative & agile measurement tools for a safe global infrastructure. Combining VHG, ARMI, MBH & Paragon Scientific, we deliver a wide range of petrochemical, metal, mining, powder & physical reference materials. - Mikromol Mikromol offers a portfolio of 7,000+ high-quality accredited pharmaceutical API, impurity & excipient reference standards, >95% ready to ship alongside market leading COAs. We also provide RMs management services & custom manufacturing. - Clinical Diagnostics LGC Clinical Diagnostics develops and manufactures a comprehensive portfolio of catalogue and custom-developed diagnostic quality solutions, biological and reagent component materials for the extended life sciences industry. - LGC Genomics LGC Genomics offers a custom DNA sequencing service. It is comprised of Biosearch Technologies & LGC Axolabs. i) Biosearch Technologies offers GMP and RUO Oligonucleotides, Molecular biology reagents, NGS kits and enzymes, Oligo synthesis reagents and instruments, PCR reagents and instruments, and sample prep reagents and instruments. ii) LGC Axolabs offers a unique services portfolio for the development of nucleic acid therapeutics and nucleic acid-based medicines.

Mangelsfeld 4,5,6 Bad Bocklet, 97708 GermanyLabor LS is a contract laboratory located at a single site in Germany. There, approximately 550 colleagues perform microbiological, biochemical and physicochemical tests according to cGMP on 10.000 m2 of state of the art laboratories for more than 1500 customers comprising small businesses as well as the leading global players in the pharmaceutical industry. The quality is approved by international authorities including FDA. In line with this, more than 70 customer audits are managed per year. Labor LS performs routine testing as well as method development, verifications, validations and transfers on sterile and non-sterile raw materials as well as on finished products including ATMPs.

Industriestraße 7 - 9 D - 23812 Wahlstedt GermanyLichtenheldt manufactures pharmaceutical and healthcare products in both liquid and semi-solid forms.

Emmerthal, NDS, 31860 GermanyLomapharm offers production of pharmaceuticals, packaging, production development, and raw material analysis services.

Langes Feld 5 31860 Emmerthal GermanyLomapharm offers production of pharmaceuticals, packaging, production development, and raw material analysis services.

Am Klopferspitz Planegg, BY, 82152 GermanyLEUKOCARE supports its partners with formulation development, related services and know how in order to implement the proprietary SPS® formulation technologies in the products of our partners. We offer specialized analytical methods for the analysis of biopharmaceuticals and a successful formulation development.

401 Erkrather Straße Düsseldorf, NRW, 40231 GermanyLenioBio is a life science biotech company offering a disruptive protein expression technology. ALiCE® enables the discovery, development and production of difficult-to-express proteins. The ALiCE® technology represents an eukaryotic cell-free protein expression platform that is scalable and changes the way proteins are produced today, across all industries. If you are a scientist being active in protein expression and want to produce difficult-to-express proteins or increase yields, efficiency or scalability, LenioBio's ALiCE® technology is the right option. Our technology is available in kits as well as a Protein Service that can be ordered directly from the scientist.com platform. By ordering the feasibility expression study for cytosolic or microsomal/membrane proteins you will get the quick and well-founded information if expression of your proteins of interest is feasible.

Lochhamer Str. 11MediGene focuses on the development of cancer drugs with emphasis on their liposome technology.

Robert-Rossle-Strasse 10MerLion provides natural product sample/extract supply, extract profiling, assay development, HTS, compound purification and structural identification, biocatalyst isolation and strain improvement services.

Henkestraße 91Molecular Networks provides custom designed applications, metabolism analysis, metabolic engineering, molecular property modeling, and chemical databases.

Reutlingen, BW GermanyMedimod Pharmacology Services offer mental disorder models, drug efficacy, behavioral pharmacology, and phenotyping.

25 Aspenhaustraße Reutlingen, BW, 72770 GermanyMediagnost is dedicated to the research and manufacture of diagnostic test systems and has evolved into a modern and innovative enterprise whose products and diagnostic tools are marketed across the globe.

Pfotenhauerstr. 108 01307 Dresden GermanyThe DNA sequencing and genotyping service provides Sequencing services and support, and routine genotyping of model organisms used in the institute such as mouse, zebrafish, and Drosophila making use of state of the art technologies.

Heidelberg, BW GermanyMultimetrix provides quantitative gene expression analysis, expression profiling, RNA and screening services.

Vor dem Kreuzberg 17M-fold Biotech provides custom GPCR production, antigens, antibody characterization, labeling, expression, cloning, and purification services.

In House Green 15 79312 Emmendingen, GermanySince its inception in 1992, the medical-scientific laboratory is menal a family run business. Responsibility, trust and reliability are our top priority. The success of our clients confirms daily the quality of our work. We attach great importance also to the personal supervision of the projects from the beginning. For our clients we perform the analysis work on the principle of "glass laboratory" by: At any time, we guarantee our customers a glimpse of the recovered data. With innovative approaches, we support our customers in analytical problems. A wide range of methods available for routine analysis as well as special projects. At our location in Emmendingen in Freiburg stands us in the square since 2001 new company building 480 laboratory space.

Planegg, BY, 82152 GermanyMetabion offers DNA, RNA, ZNA, and other probes in addition to custom peptide, antibody, and oligonucleotide services.

Industriestr 1b Überherrn, 66802 GermanyMyBiotech is a CDMO on the fields of Biotechnology and Pharmaceuticals. Biotechnological production is covered with all aspects of upstream and downstream processes focusing on cell disruption with our propriety technology and purification with chromatographic methods such as ion exchange and supercritical fluid chromatography. Biotechnological production of active pharmaceutical ingredients and natural substances is also one of the core aspects of our business. Our products include Algae derived Omega-3 fatty acids, innovative Omega-3 formulations Curcumin, Phycocyanin along with plant derived natural supplements. Pharmaceutical division is specialized on development and technology transfer of nanoparticle and microparticle formulations from concept through development all the way up to GMP manufacturing. We are continuously developing and adapting innovative production methods for GMP manufacturing and processing of particulate systems. We support you with our innovative technologies to bring your project one step closer to success.

Zirkusweg 2 Hamburg, 20359 GermanyMindpeak is Europe's leading provider of AI software for pathology. Over 15,000 patients have been diagnosed with the help of Mindpeak's AI. With a focus on tissue biomarker analysis and discovery, Mindpeak serves clinical laboratories and biopharma companies around the world. Mindpeak's AI-algorithms were the first to be used in routine clinical diagnostics in the US and EU. Mindpeak is available on over 17 pathology image viewing systems making it a very easy choice to assist in any commercial launch on a international scale.

Zirkusweg 2 Hamburg, 20359 GermanyMindpeak is Europe's leading provider of AI software for pathology. Over 15,000 patients have been diagnosed with the help of Mindpeak's AI. With a focus on tissue biomarker analysis and discovery, Mindpeak serves clinical laboratories and biopharma companies around the world. Mindpeak's AI-algorithms were the first to be used in routine clinical diagnostics in the US and EU. Mindpeak is available on over 17 pathology image viewing systems making it a very easy choice to assist in any commercial launch on a international scale.

Lochhamer Schlag 11 Gräfelfing, Bavaria, 82166 GermanyThe DNA-PAINT company

Tegeler Weg 33 Berlin, 10589 GermanyMetanomics Health applies metabolite profiling to develop tools and solutions for drug discovery and development, diagnostics and nutritional research.

Mary-Astell-Straße 10Molzym offers microbial identification, PCR assay development, genomic analysis, DNA isolation and amplification products and services.

Dohrweg 63 Moenchengladbach , 41066 GermanyMLM Medical Labs is a global leading specialty and central laboratory with comprehensive research services and analytical capabilities. Offering standard and fully customizable biological specimen testing and auxiliary logistics services across a wide spectrum of therapeutic areas, MLM adds value at every stage of the product development process, from nonclinical and preclinical through phase IV clinical trials. With their strong reputation for scientific expertise, passionate approach to customer care, and adherence to quality data, MLM empowers clients ranging from emerging biotech to top ten global pharma companies to reach confident clinical decisions that ultimately serve to improve patient lives.

Wallstraße 10 Mönchengladbach D-41061 GermanyMLM Medical Labs is a global leading specialty and central laboratory with comprehensive research services and analytical capabilities. Offering standard and fully customizable biological specimen testing and auxiliary logistics services across a wide spectrum of therapeutic areas, MLM adds value at every stage of the product development process, from nonclinical and preclinical through phase IV clinical trials. With their strong reputation for scientific expertise, passionate approach to customer care, and adherence to quality data, MLM empowers clients ranging from emerging biotech to top ten global pharma companies to reach confident clinical decisions that ultimately serve to improve patient lives.

Nussbaumstr. 10, 80336 Munich, GermanyMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

Gmunder Strasse 53, 81379 München, GermanyMedpace is a Full Service CRO and offers clinical development services including medical writings, biometrics, regulatory affairs and quality assurance. Also offered are Central Lab Services, Bio-Analytical, Biomarker Testing, BioSample Storage and Management, Long-term BioRepository, Core Lab Services, Imaging, and a Phase I Safety Clinic.

Mendelstr. 17 Münster, Please select, 48149 GermanyWe have expertise in research, pre-clinical and clinical services for dermatological, therapeutics, cosmeceuticals and nutraceutical applications. Based on our excellent research background, we are specialized in hair and skin physiology and pathology. We provide state-of-art in vitro cell models, ex vivo organ culture models and cutting-edge techniques for pre-clinical and clinical studies.

Mendelstr. 17 Münster, Please select, 48149 GermanyWe have expertise in research, pre-clinical and clinical services for dermatological, therapeutics, cosmeceuticals and nutraceutical applications. Based on our excellent research background, we are specialized in hair and skin physiology and pathology. We provide state-of-art in vitro cell models, ex vivo organ culture models and cutting-edge techniques for pre-clinical and clinical studies.

Hedwigstr. 2-8 D-76199 Karlsruhe, GermanyMicroMol provides microbiology, cell biology, protein services, assay development, and cell banks.

Köpenicker Straße 325 Berlin, D-12555 GermanyMinerva Biolabs supplies products and offers services for quality control of water samples, cell cultures, and biological materials.

Lena-Christ-Strasse 48Morphosys offers therapeutic, diagnostic, and custom monoclonal antibodies.

INF 242 Heidelberg, 69120 GermanyMultiplexion specializes in cell line authentication and contamination testing.

Heidelberg, BW GermanyMultiplexion specializes in cell line authentication and contamination testing.

Ingelheim am Rhein, RP GermanyMidas Pharma offers custom manufacturing and synthesis services for API, intermediates, and biologics.

Metapark 1, d-79297 Winden, GermanyMetalife is a bioinformatics company, dedicated to enabling the life science industry to improve its productivity through integrative bioknowledge solutions that cover the complete research and development value chain. Buying our products and services facilitates your organization to activate, compare and analyze data from all public and proprietary sources. We transform abundant amounts of information into valuable knowledge by semantic data integration, text mining and high-level data analysis. With Metalife Trinity we provide a professional standard solution that incorporates a fundamental set of tools for algorithmic analysis and text mining, as well as database integration, querying and automatic update. However, we fully acknowledge each customer's unique needs and requirements. Therefore, Metalife Trinity is implemented in an intelligent and remarkably flexible way. Our software's core adaptive nature allows us to customize it rapidly for the specific requirements of virtually any organization, active in the life sciences field. Furthermore, since year 2000, we have proven repeatedly our ability to develop custom specific software tools from scratch in a collaborative, interactive work process with our customers and partners.

Chemical Genomics Centre Otto-Hahn-Str. 11 Dortmund 44227 GermanyMax Planck Institute of Mol. Physiology provides phenotypic screening assays, compound libraries, microarrays, and protein-protein interaction analysis.

Karl-Weinmair-Str. 5 D-80807 München DeutschlandMolekula is a manufacturer and distributor of Fine Chemicals and Biochemicals in Semi-Bulk and Research quantities.

Engesserstr. 4aSGS M-Scan offers mass spectrometry and chromatography services, including protein analysis, glycosylation analysis, antibody analysis, oligonucleotide analysis and bioanalysis.

Pfotenhauerstr. 108Max Planck Institute of Molecular Cell Biology and Genetics offers antibody, DNA sequencing, flow cytometry, mass spectrometry, transgenic, gene expression, and high throughput services.

20 Rotenburger Straße Hannover, NDS, 30659 GermanyMosaiques Diagnostics provides clinical proteomic services.

20 Rotenburger Straße Hannover, NDS, 30659 GermanyMosaiques Diagnostics provides clinical proteomic services.

Rotenburger Str. 20 Hannover, Not US or Canada, 30659 GermanyMosaiques Diagnostics provides clinical proteomic services.

Bayerstr. 85a, 80335 M nchen, GermanyMolecular Connections offers software tools for drug discovery.

Schelztorstraße 54 Esslingen am Neckar, Baden-Württemberg, 73728 GermanyWe (micro-biolytics) developed a new spectroscopic method by bringing together innovative technologies to achieve measurements on aqueous samples with unprecedented accuracy and detection sensitivity. The patented AquaSpec™ measurement method provides a powerful technology platform. Short measurement times, elimination of expensive reagents and sample preparation, complete digitization of results, and high information content open up versatile market access for this technology while offering significant time and cost advantages. AquaSpec™ technology is applicable in a wide variety of fields such as medical diagnostics, process and food analysis as well as (bio-)pharmaceutical drug development, R&D and toxicology. micro-biolytics also offers a wide range of services - with the aim of always meeting customer expectations in a competent, reliable and confidential manner. The spectrum ranges from innovative development of individual applications to service measurements in combination with statistical-mathematical data evaluation.

27 Siemensstraße Berlin, Berlin, 12247 GermanyMedicover is a leading international healthcare and diagnostic services provider headquartered in Sweden and listed on Nasdaq Stockholm. Established in 1995 in response to the growing demand for high-quality healthcare services in Poland, Medicover subsequently expanded to other countries, fulfilling similar needs. Today, Medicover’s largest operations are in Poland, Germany, Romania India and Ukraine. Medicover provides a broad spectrum of healthcare services via an extensive network of ambulatory clinics, hospitals, specialty-care facilities, laboratories and blood-drawing points through two divisions – Healthcare Services and Diagnostic Services. Healthcare Services – offers high-quality care based on its Integrated Healthcare Model and a broad offering of specialty-care services with a focus on health and wellbeing. Services are offered in 129 medical clinics, 32 hospitals, 64 dental clinics, 26 fertility clinics and 77 gyms. The major markets are Poland, India and Romania. Diagnostic Services – offers a broad range of diagnostic services including a wide range of laboratory tests in all major clinical pathology areas, ranging from routine to advanced tests and from prevention to monitoring of treatments. The business is conducted through a network of 99 laboratories, 852 blood-drawing points and 24 clinics in more than ten countries. The major markets are Germany, Ukraine, Romania and Poland. For more information, visit www.medicover.com MICS’ services include and are organized along discrete lines of activity including: Central Lab Services, Biospecimen Management, Recruitment, Management & Data, and Precision Medicine. Present and tightly integrated in all Medicover geographies and far beyond, MICS employs a dedicated team of highly specialized staff including clinical and diagnostics specialists, contract research veterans, account managers, project managers, logistics experts, analysts, and more.

Rudolf-Wissell-Straße 28a Göttingen, 37079 GermanySeparating the pharmacological wheat from the chaff is the primary goal of myriamed. Our proprietary human cell and engineered tissue models allow for the simulation of health and disease in the dish. Our platform technologies find broad applications in early stages of drug discovery and refinement of the most promising therapeutic candidates.

Calwerstrasse 7MFT Services offers microarray, expression profiling, gene expression, and genotyping services.

Lotzestrasse 22aMoBiTec offers proteins, antibodies, in vitro assay kits, and other reagent products in addition to offering custom organic synthesis, immobilization, and cDNA library construction services.

Ebersberg, BY, 85560 GermanyMWG Biotech offers bioinformatics, gene synthesis, siRNA services, sequencing, and library generation.

Schneegloeckchenstrasse 47 Berlin, 10407 GermanyMolnar-Institute for applied chromatography offers HPLC software solutions, courses, and method development services, and employs state-of-the-art software tools such as DryLab® and PeakMatch® to maximize efficiency in HPLC laboratories and minimize expensive trial-and-error approaches to method refinement.

Berlin, Berlin GermanyMolnar-Institute for applied chromatography offers HPLC software solutions, courses, and method development services, and employs state-of-the-art software tools such as DryLab® and PeakMatch® to maximize efficiency in HPLC laboratories and minimize expensive trial-and-error approaches to method refinement.

Misburger Straße 81 BMediconomics offers clinical research services including product development, regulatory affairs, medical writing, clinical trial monitoring, project management, data management, and pharmacovigilance.

Paul-Gerhardt-Allee 42Metronomia Clinical Research offers clinical research services including project management, data management, medical writing, biostatistics, quality management, and E-clinical services.

Munich, BY GermanyMetronomia Clinical Research offers clinical research services including project management, data management, medical writing, biostatistics, quality management, and E-clinical services.

Moskauer Strasse 25M.A.R.C.O. offers clinical research services such as proof of concept, quality assurance, quality assurance, and project management.

Universitätsstr. 10 c/o Universität Konstanz Fach 726 78457 Konstanz GermanymyPOLS Biotec is developing new generations of DNA polymerases for advanced and reliable applications e.g. in personalized medicine, pathogen detection, DNA and RNA diagnostics, forensics, and many more. Our research & development activities include: Improved DNA polymerases for SNP detection and methylation specific PCRs. Pathogen detection assays, e. g. for Influenza- and Norovirus diagnostics. Thermostable DNA polymerases with reverse transcriptase activity. Inhibitor resistant polymerases for direct PCRs from your sample, such as whole blood, saliva, bacteria, cell-pellets, plants, etc.

10 Robert-Rössle-Straße, Berlin, Berlin 13125, DEThe Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) is one of the most important centers for biomedical research. The MDC was founded in 1992, based on institutes of the former Academy of Sciences of the GDR, with a mission of translating discoveries from molecular research into applications to improve the prevention, diagnosis, and treatment of major human diseases. The site – rich in tradition – in Berlin-Buch, home to hospital clinics, research institutes and a flourishing biotech industry, is fertile ground for interdisciplinary and patient-oriented research. As a testament to its success, the MDC has been ranked 14th in the Thompson Reuters list of the world’s 20 best research institutes for molecular biology and genetics, based on our publication record. Currently about 1,600 staff members and guests work at the MDC. The annual institutional budget amounts to approximately 76 million Euros, 90 percent of which is received from the federal government and 10 percent from the State of Berlin. This is complemented by about 21 million Euros obtained by MDC researchers through grants and other external sources.

Plambeckskamp 2Microscopy Services provides electron microscopy, embedding services, microtomy, and fixation.

Marienburger Str. 1 Berlin, 10405 GermanyMicroDiscovery is a leading provider of high quality software solutions and bioinformatic data analysis services in the areas of innovative diagnostics, personalized medicine and biomolecular research.

Technologie Park Heidelberg Im Neuenheimer Feld 582 69120 Heidelberg GermanyMind the Byte is a bioinformatics company that develops and provides software for computational drug discovery using Big Data and Machine Learning (AI) approaches. We work with partners on a consultancy basis or offer an easy to use Software as a Service (SaaS) package to allow clients to apply the High-performance computing platform on a flexible pay-per-use basis without investment in hardware or software licenses. Mind the Byte has developed a versatile set of applications using cloud computing which lowers the entry barrier to the technology, e.g. i) virtual profiling methods to facilitate the identification of targets and mechanisms of action of phenotypic screening hits or natural products with reported activity ii) virtual screening methods to identify compounds acting on a specific target by mining internal or commercial compound libraries, to expand hit or lead series and to conduct repurposing of known drugs. iii) MtBDock - a fully integrated docking protocol reducing the amount of false positives by incorporation of all prosthetic groups and conformational minimization iv) SmartDock - an experimentally validated docking protocol with further improved performance based on machine learning of PDB target-ligand interactions Mind the Byte is an Amazon Web Services technology partner - a seal of quality that has only been awarded to five companies in this sector – to ensure security and reliability. The company was founded in 2011 by Alfons Nonell-Canals, a specialist in computer-aided drug design and in large-scale chemical and biological analyses, and has since expanded with an experienced staff.

Mauchener Str. 14 D - 79379 Muellheim, 79379 GermanySpray Freeze Drying: - process equipment supply in lab, pilot and manuf . scale - technology development - process parameter development & scale up

Platz der Einheit 1MakroCare is a clinical research organization and offers late phase studies, quality assurance, regulatory affairs, clinical monitoring and data management.

Panoramastrasse 1 Berlin, 10178 GermanyModelate is a software company that speaks the Healthcare language. We digitally improve the perception of your evidence. We are a chain link that helps you communicate cost-effectiveness, value & budget impact in an interactive way, ultimately understandable to your stakeholder. Our main goal is to help you convince your stakeholder with: - digital stories - interactive global value dossiers - digital health economics models, e-detailers - interactive maps

Schumannstr. 144 Offenbach am Main, Hessen, 6369 GermanyHistology, immunohistochemistry, cytology and hematology: As the first spin-off of the Senckenberg Research Institute provides the Morphisto GmbH in its modern histology lab comprehensive services for medical and biological research projects and contract work. As an interface between science and industry, we are involved in product development and clinical trials and also produce ready-to-use laboratory chemicals for histology, cytology and metallography. We are your competent partner for all questions concerning histology, cytology, immunohistochemistry, comparative anatomy and evolutionary research. Benefit from our many years of experience in research, application and development. In our histology laboratory, we master all methods of histology and immunohistology, from classical paraffin histology, plastic histology and separation thin-section technology to the production of whole body sections for autoradiography with freezing microtomes.

Weismüllerstr. 45 Frankfurt am Main , 60314 GermanyHistology, immunohistochemistry, cytology and hematology: As the first spin-off of the Senckenberg Research Institute provides the Morphisto GmbH in its modern histology lab comprehensive services for medical and biological research projects and contract work. As an interface between science and industry, we are involved in product development and clinical trials and also produce ready-to-use laboratory chemicals for histology, cytology and metallography. We are your competent partner for all questions concerning histology, cytology, immunohistochemistry, comparative anatomy and evolutionary research. Benefit from our many years of experience in research, application and development. In our histology laboratory, we master all methods of histology and immunohistology, from classical paraffin histology, plastic histology and separation thin-section technology to the production of whole body sections for autoradiography with freezing microtomes.

Magdeburg, GermanyMeltec offers high content analysis and visualization services and tools.

Am Klopferspitz 18 82152 Martinsried GermanyThe Imaging Facility provides access to high grade fluorescence research microscopes for scientists of the Max Planck Institute of Biochemistry (MPIB) to observe and analyze fixed samples as well as living organisms. Besides instructing first-time users in basic operation of hardware and software, user training for specialist features and continued assistance in acquisition, processing and analysis of images is offered. At present the Imaging Facility holds five microscope systems: Zeiss LSM780 confocal laser scanning microscope including software for FCS (Fluorescence Correlation Spectroscopy) and RICS (Raster Image Correlation Spectroscopy) Leica TCS SP8 confocal laser scanning microscope with two hybrid detectors and resonant scanner Perkin Elmer UltraVIEW Vox Spinning Disk Confocal including FRAP unit AppliedPrecision® DeltaVision RT® system including the quantifiable laser modules Leica TCS SP2 confocal laser scanning microscope All imaging systems are equipped with motorized xyz stages and incubation chambers with temperature and CO2 control.

Am Klopferspitz 18 Martinsried, 82152 GermanyThe Imaging Facility provides access to high grade fluorescence research microscopes for scientists of the Max Planck Institute of Biochemistry (MPIB) to observe and analyze fixed samples as well as living organisms. Besides instructing first-time users in basic operation of hardware and software, user training for specialist features and continued assistance in acquisition, processing and analysis of images is offered. At present the Imaging Facility holds five microscope systems: Zeiss LSM780 confocal laser scanning microscope including software for FCS (Fluorescence Correlation Spectroscopy) and RICS (Raster Image Correlation Spectroscopy) Leica TCS SP8 confocal laser scanning microscope with two hybrid detectors and resonant scanner Perkin Elmer UltraVIEW Vox Spinning Disk Confocal including FRAP unit AppliedPrecision® DeltaVision RT® system including the quantifiable laser modules Leica TCS SP2 confocal laser scanning microscope All imaging systems are equipped with motorized xyz stages and incubation chambers with temperature and CO2 control.

Neurather Ring 1 51063 Köln (Cologne) GermanyMEDA Manufacturing manufactures solid, semi-solid and liquid dosage forms and various customer-specific specialities.

Ingolstädter Landstrasse 1 Neuherberg, 85764 Germany

Kieler Str. 99 – 105Momentum Pharma Services (MPS) offers clinical research services including clinical development, data management, project management, first in man studies, and PK studies.

MPI of Biochemistry, Am Klopferspitz 18, 82152 MartinsriedThe Transgenic Core Facility is a joint facility of the Max Planck Institutes of Biochemistry and Neurobiology. The service is open to all departments and groups of the two Institutes. Research with genetically engineered mouse models is dependant on the availability of specific techniques, highly specialized laboratory equipment and skilled staff. The Transgenic Core Facility provides the lab infrastructure for the maintenance and generation of transgenic mouse models and the complete set of gene targeting and transgenesis technologies in a setting of specific pathogen free (SPF) animal housing. The facility offers support, advice and counselling for non-specialists in recombinant embryonic stem (ES) cell technology, de novo establishment of mouse ES cell lines, gene targeting experiments and the approval of certain animal experiments.

Folienverarbeitung Lohmannstraße 15 D 56626 Andernach GermanyMaropack provides films, bags and printing.

Walther-Rathenau-Str. 49aMICROMUN offers testing of antiviral activity, virus clearance studies, diagnostic antigens, and molecular biological diagnostics.

Wolfgang-Küntscher-Strasse 14 Hennigsdorf, Brandenburg, 16761 GermanyApplications Lab für Amino Acid Analysis

moloX GmbH Takustr. 6 14195 Berlin GermanymoloX GmbH was founded 2012 in Berlin, Germany by Dr. Holger von Moeller and Dr. Bernhard Loll. The company is exclusively owned by its founders and does not rely on any external funding reflecting its reliability, quality and ease of relationship with clients. moloX aims at providing customers with highly pure proteins for pharmaceutical, biochemical, biotechnological, and academic research. See products & services for a portfolio of services. moloX

THIELALLEE 63 BErlin, Berlin, 14195 GermanymoloX GmbH was founded 2012 in Berlin, Germany by Dr. Holger von Moeller and Dr. Bernhard Loll. The company is exclusively owned by its founders and does not rely on any external funding reflecting its reliability, quality and ease of relationship with clients. moloX aims at providing customers with highly pure proteins for pharmaceutical, biochemical, biotechnological, and academic research. See products & services for a portfolio of services. moloX

Takustr. 6 Berlin, Berlin, 14195 GermanymoloX GmbH was founded 2012 in Berlin, Germany by Dr. Holger von Moeller and Dr. Bernhard Loll. The company is exclusively owned by its founders and does not rely on any external funding reflecting its reliability, quality and ease of relationship with clients. moloX aims at providing customers with highly pure proteins for pharmaceutical, biochemical, biotechnological, and academic research. See products & services for a portfolio of services. moloX

Mikro-Forum-Ring 5 Wendelsheim, Rheinland-Pfalz, 55234 Germanymfd Diagnostics GmbH is a service provider for universities, other academic institutions, research-based pharmaceutical companies, biotech companies, medical-biological research institutions and medical devices manufacturers. Service-orientation and individual consulting of customers is of primary importance for us. Our success is based on our competent and positive team and our state-of-the-arts technology. Profit from our comprehensive services that meet the highest quality requirements!

Zeppelinstraße 3 Hallbergmoos , 85399 GermanyAbout Metabolon, Inc. Metabolon, Inc. has invested more than 20 years into building the best metabolomic competency in the world to reveal biological insights otherwise unseen. Today, Metabolon enables, accelerates, and supports drug development through biomarker discovery, understanding the mechanism of action, patient stratification, and more, as evidenced by >3,000 citations, numerous high-impact publications, case studies, and customer testimonials.   Metabolomics can instantaneously provide a snapshot of the entire physiology of a living being by studying the metabolites or the small-molecule end products of metabolism. The resulting full picture of a biological system enables a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome.   Metabolon’s 4Cs approach sets the standard of performance across Coverage, Competency, Comparability, and Capacity for the most complete biological insights into disease state and physiological reactions in the present time. The company’s technology provides the fullest view of the metabolome to detect and identify metabolites with the highest fidelity. Metabolon has the world’s most extensive reference library of compounds that currently includes 5,400+ total known molecules, enabling the ability to compare thousands of molecules to reveal new insights and opportunities across diverse markets.  Metabolon offers scalable, customizable metabolomics solutions from discovery through clinical trials and product life-cycle management. Metabolon is equipped to deliver biologically relevant insights to address some of the most challenging and pressing questions in the life sciences. Metabolon is ISO 9001:2015 certified for analytical and diagnostic testing of biological specimens, certified by Clinical Laboratory Improvement Amendments of 1988 (CLIA), and accredited by the College of American Pathologists (CAP) for diagnostic testing on human specimens. The company, founded in 2000, is based in Research Triangle Park, North Carolina. What is Metabolomics? Metabolomics, the study of metabolites, the small-molecule end products of metabolism collectively known as the metabolome, provides the full picture of a biological system enabling a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome. Metabolon’s proprietary untargeted metabolomics platform reveals biological insights otherwise unseen. Metabolon sets the standard in metabolomics and accelerates research and product development in every sector from pharma and agriculture to consumer products and wellness, as well as population health and academia. Why Metabolon? Metabolon’s approach sets the standard of 4Cs for performance: Coverage, Competency, Comparability and Capacity for the most complete picture. The unmatched depth provides functional metabolite understanding, fuelling deep insights and enabling our clients to accelerate research and product development success in the pharma, population health, consumer products, agriculture, wellness, and academic research sectors. Metabolon offers a range of metabolomics service offerings that support and advance research at every stage. Wherever you are in your research and development journey, our team of experts will work with you to clearly define your goals and develop a customized plan to meet them. We offer applications throughout the drug discovery and preclinical development continuum and product lifecycle: Discovery – Target Selection Novel biomarkers Disease taxonomy Target discovery Target selection Mechanism of action Inherent translatability Lead - Candidate Selection Lead optimization Early toxicological and secondary effects Candidate selection Preclinical Efficacy biomarkers PD biomarkers Off-target effect characterization Clinical Clinical Responders vs non-responders Patient stratification Efficacy signals Prodromal safety signals Lifecycle Management Blackbox warning mitigation Real-world evidence New indication identification Off-target effects Bioprocessing optimization

Zeppelinstraße 3 Suite 100 Hallbergmoos , 85399 GermanyAbout Metabolon, Inc. Metabolon, Inc. has invested more than 20 years into building the best metabolomic competency in the world to reveal biological insights otherwise unseen. Today, Metabolon enables, accelerates, and supports drug development through biomarker discovery, understanding the mechanism of action, patient stratification, and more, as evidenced by >3,000 citations, numerous high-impact publications, case studies, and customer testimonials.   Metabolomics can instantaneously provide a snapshot of the entire physiology of a living being by studying the metabolites or the small-molecule end products of metabolism. The resulting full picture of a biological system enables a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome.   Metabolon’s 4Cs approach sets the standard of performance across Coverage, Competency, Comparability, and Capacity for the most complete biological insights into disease state and physiological reactions in the present time. The company’s technology provides the fullest view of the metabolome to detect and identify metabolites with the highest fidelity. Metabolon has the world’s most extensive reference library of compounds that currently includes 5,400+ total known molecules, enabling the ability to compare thousands of molecules to reveal new insights and opportunities across diverse markets.  Metabolon offers scalable, customizable metabolomics solutions from discovery through clinical trials and product life-cycle management. Metabolon is equipped to deliver biologically relevant insights to address some of the most challenging and pressing questions in the life sciences. Metabolon is ISO 9001:2015 certified for analytical and diagnostic testing of biological specimens, certified by Clinical Laboratory Improvement Amendments of 1988 (CLIA), and accredited by the College of American Pathologists (CAP) for diagnostic testing on human specimens. The company, founded in 2000, is based in Research Triangle Park, North Carolina. What is Metabolomics? Metabolomics, the study of metabolites, the small-molecule end products of metabolism collectively known as the metabolome, provides the full picture of a biological system enabling a deep understanding of health, disease, and treatment response, whether influenced by genes, the environment, epigenetics, or the microbiome. Metabolon’s proprietary untargeted metabolomics platform reveals biological insights otherwise unseen. Metabolon sets the standard in metabolomics and accelerates research and product development in every sector from pharma and agriculture to consumer products and wellness, as well as population health and academia. Why Metabolon? Metabolon’s approach sets the standard of 4Cs for performance: Coverage, Competency, Comparability and Capacity for the most complete picture. The unmatched depth provides functional metabolite understanding, fuelling deep insights and enabling our clients to accelerate research and product development success in the pharma, population health, consumer products, agriculture, wellness, and academic research sectors. Metabolon offers a range of metabolomics service offerings that support and advance research at every stage. Wherever you are in your research and development journey, our team of experts will work with you to clearly define your goals and develop a customized plan to meet them. We offer applications throughout the drug discovery and preclinical development continuum and product lifecycle: Discovery – Target Selection Novel biomarkers Disease taxonomy Target discovery Target selection Mechanism of action Inherent translatability Lead - Candidate Selection Lead optimization Early toxicological and secondary effects Candidate selection Preclinical Efficacy biomarkers PD biomarkers Off-target effect characterization Clinical Clinical Responders vs non-responders Patient stratification Efficacy signals Prodromal safety signals Lifecycle Management Blackbox warning mitigation Real-world evidence New indication identification Off-target effects Bioprocessing optimization

Aspenhaustrasse 21 Reutlingen, 72770 GermanyMulti Channel Systems MCS GmbH specializes in development of precise scientific measuring instrumentation in the field of electrophysiology for research groups at universities and for the pharmaceutical industry.

Raiffeisenstraße 35 Donaueschingen, D-78166 GermanySince over a decade MCAT works in the range of metalorganic and elementorganic catalysts and metal-catalysed transformations in Organic Chemistry, Life Sciences and Polymer Science. With it we continuously expand our range of products. *Our Offer* MCAT provides fundamental background in synthesis of metal organic complexes and has developed a highly efficient proprietary process for the synthesis of asymmetric ansa-Metallocenes which can be applied in the production of enantiomeric pure intermediates or compounds for the production of pharmaceuticals. MCAT Life Science Technologies offers you a wide range of high quality products and individual tailor made services in the range of Organic and Bioorganic Chemistry and Life Sciences. *Custom Synthesis* MCAT is specialized in the synthesis of metalorganic compounds with the following active metals: Titanocene, Zirkonocene, Hafnocene, Vandocene, Niob, Platinum, Palladium and Nickel compounds u.a.m and in the synthesis of organic and bioorganic compounds like Saccharides/Glycosides, Azido- and Alkinyl-Buildingblocks,Heterocycles, Ligands, and many more ranging from milligrams up to multi kilograms. *Research* Regarding your outsourcing-strategies MCAT offers a complete research programme from planning to documentation stage on a confidential custom basis. The MCAT-Team will assist you at each step, from information to evaluation, research and production of catalysts. Our experience is at your service!

Starenstrasse 2 D-93077 Bad Abbach GermanyAdvanced Cell and Tissue Cultures 3D Cultures Tools for Regenerative Medicine Tissue Engineering Biomaterial Testing Pharmaceutical Research

Lise-Meitner-Strasse 2medDOC offers translations in the fields of medicine and pharmacy.

Colonia-Allee 15 51067 Köln GermanyMadaus provides phytopharmaceuticals around the world.

Am Klopferspitz 18 Martinsried 82152 GermanyMax Planck Institute of Biochemistry provides DNA services, oligoRNA synthesis, spectrometry, protein services, and post-translational modifications.

1 Industriestraße Überherrn, SL, 66802 GermanyMJR PHARMJET IS A PROVIDER OF ANALYTICAL AND FORMULATION DEVELOPMENT SERVICES FOR PHARMACEUTICALS WITH A SPECIAL FOCUS ON THE LOW SOLUBLE SUBSTANCES. WE ARE YOUR RELIABLE PARTNER FOR DEVELOPMENT OF ALL DOSAGE FORMS INCLUDING SOLID, LIQUID AND SEMI SOLIDS. MJR PHARMJET ENSURES SOLUTION FOR YOUR FORMULATION CHALLENGES WITH INNOVATIVE TECHNOLOGIES, WHERE WE COMBINE OUR EXPERTISE WITH HIGH QUALITY STANDARDS. THANKS TO OUR WIDE RANGE OF SERVICES WE ACCOMPANY THE WHOLE WAY FROM CONCEPTUAL APPROACH OVER DEVELOPMENT TO MANUFACTURING.

1 Industriestraße Überherrn, SL, 66802 GermanyMJR PHARMJET IS A PROVIDER OF ANALYTICAL AND FORMULATION DEVELOPMENT SERVICES FOR PHARMACEUTICALS WITH A SPECIAL FOCUS ON THE LOW SOLUBLE SUBSTANCES. WE ARE YOUR RELIABLE PARTNER FOR DEVELOPMENT OF ALL DOSAGE FORMS INCLUDING SOLID, LIQUID AND SEMI SOLIDS. MJR PHARMJET ENSURES SOLUTION FOR YOUR FORMULATION CHALLENGES WITH INNOVATIVE TECHNOLOGIES, WHERE WE COMBINE OUR EXPERTISE WITH HIGH QUALITY STANDARDS. THANKS TO OUR WIDE RANGE OF SERVICES WE ACCOMPANY THE WHOLE WAY FROM CONCEPTUAL APPROACH OVER DEVELOPMENT TO MANUFACTURING.

Industriestr 1b Deutschland Überherrn, Saarland, 66802 GermanyMJR PHARMJET IS A PROVIDER OF ANALYTICAL AND FORMULATION DEVELOPMENT SERVICES FOR PHARMACEUTICALS WITH A SPECIAL FOCUS ON THE LOW SOLUBLE SUBSTANCES. WE ARE YOUR RELIABLE PARTNER FOR DEVELOPMENT OF ALL DOSAGE FORMS INCLUDING SOLID, LIQUID AND SEMI SOLIDS. MJR PHARMJET ENSURES SOLUTION FOR YOUR FORMULATION CHALLENGES WITH INNOVATIVE TECHNOLOGIES, WHERE WE COMBINE OUR EXPERTISE WITH HIGH QUALITY STANDARDS. THANKS TO OUR WIDE RANGE OF SERVICES WE ACCOMPANY THE WHOLE WAY FROM CONCEPTUAL APPROACH OVER DEVELOPMENT TO MANUFACTURING.

Stübeweg 51, D-79108 Freiburg, GermanyMax Planck Institute of Immunobiology and Epigenetics offers its facilities to provide DNA sequencing, flow cytometry, live cell imaging, proteomics, transgenic mouse, and zebrafish services.

Büro DeutschlandMabtech develops and offers ELISpot, FluoroSpot and ELISA kits, kit components and reagents, ELISpot and FluoroSpot readers and Contract Lab Services.

Am Eichelgärtchen 36a iNovaParc OG26-27 Halsenbach, D-56283 GermanyMicroCombiChem GmbH provides complex tailored MedChem synthesis, isolation and structural elucidation of drug-like compounds for pharmaceutical, chemical & agrochemical R&D. Scale: mg to multi-gram amounts Main Products: - Screening Compounds - Tailored Screening Libraries - Building blocks - Tailored complex research compounds - New Reference substances and primary standards in high quality and their qualification - New innovative natural compounds and derivatives - Impurities from APIs or other mixtures and raw materials Main Strengths and Services: - Complex Synthesis in the field of Carbohydrates, Nucleosides and Heterocycles. - Advanced Screening Compound Synthesis on solid an liquid phase using sophisticated pharma-like Building-Blocks, including natural derived entities - Isolation (by Preparative HPLC-MS separation) of Impurities or Plant Ingredients followed by structure elucidation (NMR / MALDI-TOF / HR-MS) and focused synthesis of the impurity - Chiral Separations also in bulk amounts - Enzymatic Synthesis - Application of Chemoinformatical Tools and AI in Drug-Discovery.

Rheingaustrasse 190-196 Building E512 Wiesbaden, D-65203 GermanyMicroCombiChem GmbH provides complex tailored MedChem synthesis, isolation and structural elucidation of drug-like compounds for pharmaceutical, chemical & agrochemical R&D. Scale: mg to multi-gram amounts Main Products: - Screening Compounds - Tailored Screening Libraries - Building blocks - Tailored complex research compounds - New Reference substances and primary standards in high quality and their qualification - New innovative natural compounds and derivatives - Impurities from APIs or other mixtures and raw materials Main Strengths and Services: - Complex Synthesis in the field of Carbohydrates, Nucleosides and Heterocycles. - Advanced Screening Compound Synthesis on solid an liquid phase using sophisticated pharma-like Building-Blocks, including natural derived entities - Isolation (by Preparative HPLC-MS separation) of Impurities or Plant Ingredients followed by structure elucidation (NMR / MALDI-TOF / HR-MS) and focused synthesis of the impurity - Chiral Separations also in bulk amounts - Enzymatic Synthesis - Application of Chemoinformatical Tools and AI in Drug-Discovery.

Rheingaustrasse 190-196 Building E512 Wiesbaden, D-65203 GermanyMicroCombiChem GmbH provides complex tailored MedChem synthesis, isolation and structural elucidation of drug-like compounds for pharmaceutical, chemical & agrochemical R&D. Scale: mg to multi-gram amounts Main Products: - Screening Compounds - Tailored Screening Libraries - Building blocks - Tailored complex research compounds - New Reference substances and primary standards in high quality and their qualification - New innovative natural compounds and derivatives - Impurities from APIs or other mixtures and raw materials Main Strengths and Services: - Complex Synthesis in the field of Carbohydrates, Nucleosides and Heterocycles. - Advanced Screening Compound Synthesis on solid an liquid phase using sophisticated pharma-like Building-Blocks, including natural derived entities - Isolation (by Preparative HPLC-MS separation) of Impurities or Plant Ingredients followed by structure elucidation (NMR / MALDI-TOF / HR-MS) and focused synthesis of the impurity - Chiral Separations also in bulk amounts - Enzymatic Synthesis - Application of Chemoinformatical Tools and AI in Drug-Discovery.

Am Frauwald 10 DE 65510 Idstein GermanyMolecular Sensing, Inc. (MSI) is commercializing Back-Scattering Interferometry (BSI), the world’s first label-free, conformation-sensitive, free-solution assay technology for biophysical characterization of small molecule interactions with complex drug targets.

Himmelgeister Strasse 45 Duesseldorf, NRW, 40225 GermanyMolgenium is a German-based biopharmaceutical company that is dedicated to developing innovative therapies to address the complex medical needs of patients suffering from rare and severe diseases. The company's personalized approach to medicine has the potential to transform healthcare and represents a major step forward in the development of innovative and effective treatments. Molgenium specializes in cell and gene therapy, which is made from a patient's own cells, manufacturers, and product distributors. The company is focused on translating today's medical breakthroughs in cell and gene therapies into potential cures for patients.

Thueringer Strasse 15 Eschwege, 37269 GermanyMP Biomedicals is dedicated to giving scientists and researchers innovative, quality tools and superior service to aid them in their quest for ground-breaking discovery and turning the hope for life-changing solutions into a reality. The company manufactures and sells more than 55,000 products and is one of the only companies in the industry to offer a comprehensive line of life science, fine chemical and diagnostic products. MP Biomedicals is a world-wide corporation, with ISO-certified and FDA-approved manufacturing and distribution facilities throughout the globe and headquartered in Southern California. A vast network of global distributors and satellite facilities and offices throughout Europe, Asia, Australia and the Americas assures customers top quality products delivered when and where needed. No matter how dynamic the evolution of the life science and biotechnology markets, we remain committed to supporting our customers in their efforts to make new discoveries. From basic research, through scale-up, to full-scale production and diagnostic testing, MP Biomedicals serves every industry need – from specialized areas of research to supplying large scale quantities of fine chemicals. Our customers partner with us because they want a long-time player and reliable colleague in the fields of life science research and diagnostics. MP Biomedicals will never rest in our odyssey to remain at the forefront of discovery in the ever-changing biomedical industry.

Am Neuland 3Microcoat is a biotechnology company with over two decades of experience in the coating of solid phases, kit manufacturing and diagnostic testing. Microcoat offers a wide range of individual and specialized services for the diagnostic and pharmaceutical industry.

Am Neuland 3 Bernried am Starnberger See, Bavaria, 82347 GermanyMicrocoat is a biotechnology company with over two decades of experience in the coating of solid phases, kit manufacturing and diagnostic testing. Microcoat offers a wide range of individual and specialized services for the diagnostic and pharmaceutical industry.

Maschmühlenweg 36 Goettingen, 37081 GermanyMicrosynth (founded in 1989) is a European leading company in the area of DNA/RNA synthesis & analysis. The main activities are divided into following three business areas: 1. DNA/RNA SYNTHESIS DNA/RNA oligos & probes for R&D Antisense oligos (e.g. 2'-MOE or LNA-gapmers) for drug discovery DNA oligos for diagnostic applications Pilot scale synthesis (gram quantities) 2. DNA/RNA Analysis and Sequencing Sanger sequencing (incl. GMP sequencing) NGS sequencing (16S/ITS, RNA-Seq, etc.) PCR & qPCR & digital PCR Genotyping (GBS, cell lines, fragment analysis) DNA/RNA isolation 3. Contract Research/Outsourcing Assay development (e.g. IVD, liquid biopsy, etc.) Assay validation (e.g. validation of assays according to ICH guidelines) Biological tests (e.g. batch and release tests for drugs) Gene editing/gene therapy (e.g. CRISPR editing analysis, rAAV characterization) At its headquarter in Balgach close to St. Gallen Microsynth employs a staff of about 60 people. Microsynth has subsidiaries in Austria (Microsynth Austria GmbH) and Germany (Seqlab GmbH).

Business Development Center Heidelberg Carl-Friedrich-Gauß-Ring 5 Heidelberg, 69124 GermanyNucleus Biotech GmbH (Heidelberg, Germany) provides enabling reagents and services to researchers in academia and industry. Nucleus Biotech is working with selected companies who offer highly innovative tools. Nucleus Biotech´s staff is highly experienced in the life science reagents market and our customers are in the center of all our efforts. The mission is to focus on cutting edge technologies and provide core reagents and services to life science researchers.

Business Development Center Heidelberg Carl-Friedrich-Gauß-Ring 5 Heidelberg, 69124 GermanyNucleus Biotech GmbH (Heidelberg, Germany) provides enabling reagents and services to researchers in academia and industry. Nucleus Biotech is working with selected companies who offer highly innovative tools. Nucleus Biotech´s staff is highly experienced in the life science reagents market and our customers are in the center of all our efforts. The mission is to focus on cutting edge technologies and provide core reagents and services to life science researchers.

Markwiesenstr. 55Natural and Medical Science Institute (NMI) provides protein profiling, assay development, safety pharmacology, and ion channel assay services.

Reutlingen, BW GermanyNatural and Medical Science Institute (NMI) provides protein profiling, assay development, safety pharmacology, and ion channel assay services.

Wilhelm-Klees-Str. 16D Magdeburg, Sachsen-Anhalt, 39108 GermanyI am a process focused scientist with a high grade of project management experience for the process development and optimization as well as GMP manufacturing of bacterial and viral vaccines, ATMPs and alike. Disclaimer I am an employee of IDT Biologika. IDT Biologika is a leading biologics CDMO providing development and manufacturing of Viral Vaccines, Viral Vectors for Gene and Immune Therapeutics, Oncolytic Viruses, Virus-Like Particles, and aseptic fill-finish for other Biologics, with end-to-end capabilities serving companies worldwide. Consulting activities are aligned with my employer by naming an overarching work topic to avoid conflicts between IDT Biologika and my clients (written consent required). Projects and topics from the veterinary field are my main consulting activity and give the least conflict to my current employer with mainly human targeting/-relevant projects.

Langer Weg 68 Magdeburg, Sachsen-Anhalt, 39112 GermanyI am a process focused scientist with a high grade of project management experience for the process development and optimization as well as GMP manufacturing of bacterial and viral vaccines, ATMPs and alike. Disclaimer I am an employee of IDT Biologika. IDT Biologika is a leading biologics CDMO providing development and manufacturing of Viral Vaccines, Viral Vectors for Gene and Immune Therapeutics, Oncolytic Viruses, Virus-Like Particles, and aseptic fill-finish for other Biologics, with end-to-end capabilities serving companies worldwide. Consulting activities are aligned with my employer by naming an overarching work topic to avoid conflicts between IDT Biologika and my clients (written consent required). Projects and topics from the veterinary field are my main consulting activity and give the least conflict to my current employer with mainly human targeting/-relevant projects.

Käthe-Paulus-Straße 1 D-31157 SarstedtNoack Laboratorien is an independent contract research facility specialising in ecotoxicology, environmental fate and metabolism studies. Residue analysis and physico- chemical properties testing prior to product registration and according to current international regulatory requirements are also carried out. We provide experimental services in full compliance with GLP to industrial clients worldwide for the development and safety assessment of agrochemicals, biocides, consumer products, industrial chemicals and pharmaceuticals. Over the years, we have studied more than a thousand test items; this has provided us with the necessary knowledge to review new products with judgement based on a solid foundation of experience. Dr. NoackThe proprietor and head of the testing facility, Dr. Udo Noack, established the company in 1986. Since its foundation, the laboratories have always provided high quality services and have continuously improved these in line with GLP requirements.

Flößergasse 4 München, 81369 GermanyNanoTemper Technologies provides measurment technologies (instrument manufacturer) around biomolecular binding affinities, protein stability and protein aggregation

Erlenbach am Main, 63906 GermanyNAMSA is a Medical Research Organization (MRO), accelerating product development through integrated laboratory, clinical and consulting services. Driven by our regulatory expertise, NAMSA’s MRO® Approach plays an important role in translational research, applying a unique combination of disciplines—consulting, preclinical, toxicology, microbiology, chemistry, clinical and quality—to move client’s products through the development process, and continue to provide support through commercialization to post-market requirements, anywhere in the world.

In­no­va­tion­szen­trum Engen - Turm­str. 4 - D 78234 Engen, Ger­manyThe NanoCraft was found­ed in 2001 as a Spin Off from Max-Planck-In­sti­tute of Col­loids and In­ter­faces (MPI-KGF) by Dr. Sabri Akari. Spe­cial­iza­tion: Nano- and Biotech­nol­o­gy We per­form re­search and de­vel­op­ment pro­jects in the re­gion of Nano-, Bio- and Sur­face Tech­nol­o­gy with uni­ver­si­ties and in­dus­tri­al part­ners. A large num­ber of first class com­pa­nies from dif­fer­ent in­dus­tri­al branch­es are al­ready work­ing with us and use the ob­tained in­for­ma­tion for their own de­vel­op­ment with high sat­is­fac­tion. We take on com­pact pro­jects of re­search about Nano-, Bio- and Sur­face Tech­nol­o­gy. In 2003 the NanoCraft re­ceives the Dr.-Rudolf-Eber­le In­no­va­tion Award for the de­vel­op­ment of the patent­ed Chem­i­cal Force Mi­croscopy and in 2004 the tech­nol­o­gy award of the euregio.​bodensee.

Eschenheimer Anlage 1 60316 Frankfurt am MainNexus Oncology offers data management, site selection, project management, and drug development consultancy to support studies in oncology.

28 Galileo-Galilei-Straße Mainz, RP, 55129 GermanyNematel is a small company offering custom synthesis in almost all kind of organic chemistry in lab scale, specialized in liquid crystals, dichroic dyes and mesogenic lubricants.

Galileo-Galilei-Str. 28 Mainz, RLP, 55129 GermanyNematel is a small company offering custom synthesis in almost all kind of organic chemistry in lab scale, specialized in liquid crystals, dichroic dyes and mesogenic lubricants.

Ganghoferstr. 70A Munich, D-80339 GermanySales, Service and Distribution of electrophysiological instrumentation for high throughput screening

850, boulevard Sebastien Brant Bioparc, Parc d'Innovation Illkirch, Alsace-Champagne-Ardenne-Lorraine, 67400 FranceNEUROFIT is a preclinical Contract Research Organization (CRO) specialising in the evaluation of treatments for central and peripheral nervous system disorders. We offer a comprehensive list of in vitro and in vivo models covering a wide range of indications. NEUROFIT aims to facilitate your preclinical drug development by proposing the best models for your needs. Our goal is to accelerate the development of your programs by providing cost-effective methods for compound evaluation.

30 Am Feld Grafing bei München, BY, 85567 GermanyNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

25 Im Wirrigen Waltrop, NRW, 45731 GermanyNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

13 Wegenerstraße Neu-Ulm, BY, 89231 GermanyNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

Am Feld 32 Grafing , 85567 GermanyNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

Müllerstraße 178 Berlin, 13353 GermanyNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

Worpswede, GermanyNoldus Information Technology develops software and technology in the application of tracking animal behavior.

Augsburg, GermanyNoldus Information Technology develops software and technology in the application of tracking animal behavior.

Oberreifenberg (near Frankfurt), GermanyNoldus Information Technology develops software and technology in the application of tracking animal behavior.

Floehbergweg 7 Loerrach, 79541 GermanyFormed in 2017, Novomol is a Germany-based life science start-up company focused on the continued advancement of our completely novel groundbreaking computational EDEN platform to discover new safe and efficacious drugs. The EDEN platform, developed by Hans-Joachim Boehm, is a completely novel computational approach to drug discovery. Using either 2D structures of active compounds or the 3D protein structures of the target as input, EDEN generates a complex affinity fingerprint.

16, rue d'Ankara Strasbourg, Grand-Est, 67000 FranceNovAliX is a fully integrated drug discovery CRO supporting therapeutic programs from target identification to delivery of preclinical candidates. NovAliX relies upon an award-winning team of medicinal chemists and pharmacology scientists, and a variety of screening and characterization technologies, including the DNA-encoded library platform. Services include:in vitro pharmacology, protein production, structure determination, custom synthesis, chemical process research, flow chemistry, medicinal chemistry, and numerous biophysical techniques for characterization of protein -drug interactions: NMR, Native-MS, HDX-MS, SPR, ITC, MST, DLS, DSF. Structural techniques range from NMR, X-Ray Crystallography, Cryo-EM.

Bioparc Boulevard Sébastien Brant Illkirch, 67450 FranceNovAliX is a fully integrated drug discovery CRO supporting therapeutic programs from target identification to delivery of preclinical candidates. NovAliX relies upon an award-winning team of medicinal chemists and pharmacology scientists, and a variety of screening and characterization technologies, including the DNA-encoded library platform. Services include:in vitro pharmacology, protein production, structure determination, custom synthesis, chemical process research, flow chemistry, medicinal chemistry, and numerous biophysical techniques for characterization of protein -drug interactions: NMR, Native-MS, HDX-MS, SPR, ITC, MST, DLS, DSF. Structural techniques range from NMR, X-Ray Crystallography, Cryo-EM.

Gabrielenstrasse 9 Munich, D-80636 GermanyNanion Technologies offers assay development and support in patch clamp and other electrophysiology services.

Alpenstrasse 76NEXUS Biosystems provides sample management, storage, combinatorial chemistry, and protein crystallography.

Weststrasse 12NEXUS Biosystems provides sample management, storage, combinatorial chemistry, and protein crystallography.

9 Hans-Adolf-Krebs-Weg Göttingen, NDS, 37077 GermanyEncepharm was founded in 2004 as a spin-off from the German Primate Center (DPZ). With integrated expertise in all relevant preclinical disciplines and exclusive rights to unique research models originating from the DPZ, the team is perfectly placed to enhance the evaluation of novel therapeutic targets and drug candidates, as well as their preclinical development. Encepharm is particularly strong in the field of neurobiology, where the lack of suitable research models is a major obstacle to the non-rodent of novel therapies. The company management exist of several well experienced neurobiologists. The scientific advisory board consists of several professors in the Neurobiological field from all over the world.

Peter-Henlein-Strasse 2New Brunswick Scientific offers optimization, cell expertise, computer-controlled strategies, and media formulation.

De Veldmaat 10 Building: 46 High Tech Factory 7522 NM Enschede The NetherlandsNanoPhysics B.V. is an independent analytical service lab providing integral analysis solutions for many industries like semiconductor, automotive, pharmaceutical, renewable energy and nanotechnology. Besides that we also serve research institutes, suppliers, universities and high tech companies.

Am Mühlenberg 11 Potsdam, 14476 GermanyThe foundation of Nanolytics was motivated from an increasing demand for competent analytical services for small particles. Colloidal systems are gaining increasing importance in industrial production; various applications are already in existence or will be introduced into the market in the near future. Nevertheless, in many companies there is an unsatisfied demand for external assistance concerning the specific analytical problems that arise when dealing with very small particles. Furthermore, Analytical Ultracentrifugation (Nanolytics' core competence) is a classical, gold standard method for protein characterization.

Kalkstraße 218 51377 Leverkusen GERMANYNovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Friedrich-Barnewitz-Str. 4 Rostock, Mecklenburg-Vorpommern, 18119 GermanyNeuroProof is a CRO delivering services with its unique screening technology, which provides customers with high content phenotypic endpoints in pre-clinical drug development. The MEA-neurochip technology is a powerful tool to characterize functional changes in compound-induced network activity in electrically active cell cultures, including stem cells. NeuroProof offers services with its primary or iPSC-derived cell cultures for molecular readouts as: NGS gene expression profiling qPCR Western Blotting ELISA assays Immunostaining microscopy

Friedrich-Barnewitz-Str. 4 Rostock, Mecklenburg-Vorpommern, 18119 GermanyNeuroProof is a CRO delivering services with its unique screening technology, which provides customers with high content phenotypic endpoints in pre-clinical drug development. The MEA-neurochip technology is a powerful tool to characterize functional changes in compound-induced network activity in electrically active cell cultures, including stem cells. NeuroProof offers services with its primary or iPSC-derived cell cultures for molecular readouts as: NGS gene expression profiling qPCR Western Blotting ELISA assays Immunostaining microscopy

Walther-Rathenau-Str. 49A Greifswald, Not Applicable, 17489 GermanyNIPOKA is a spin-off from the University Medicine Greifswald. The team has over 20 years of expertise in podocyte research. Quantify Podocyte Foot-Process Morphology Our revolutionary procedure makes it possible to determine the exact foot process morphology in biopsies, organoids, and kidney sections of mice and rats. We can reliably identify small foot process effacement without bias. The procedure is based on super resolution microscopy and does not require electron microscopy.

Pinnauallee 4 25436 UetersenNordmark provides APIs, enzyme analysis, stability testing, biochemicals, and dosage forms.

Uetersen, SH, 25436 GermanyNordmark provides APIs, enzyme analysis, stability testing, biochemicals, and dosage forms.

Zutphenstraat 51 7575 EJ Oldenzaal The NetherlandsNanomi is specialized in the development of precisely defined functional emulsions, micro and nanospheres.

Hirschgartenallee 27Nabios offers their digital ECG core lab for high precision measurement and analysis for cardiac safety studies.

Im Neuenheimer Feld 515 D-69120 Heidelberg GermanyNovaliq GmbH is a drug delivery company located in the Heidelberg Technology Park, Germany. They develop innovative pharmaceutical formulations based on semifluorinated alkanes (SFAs).

Tscheulinstr. 21 D-79331 Teningen, GermanyNanoTools provides custom antibody development, protein chemistry, epitope services, lyophilization, and purification.

Freiburg, BW GermanyNanoTools provides custom antibody development, protein chemistry, epitope services, lyophilization, and purification.

Max-Planck-Str. 15 A Erkrath, GermanyNewlab Bioquality provides virus and TSE safety studies, protein chemistry, cell line characterization, and bioassays.

Erkrath, NRW, 40699 GermanyNewlab Bioquality provides virus and TSE safety studies, protein chemistry, cell line characterization, and bioassays.

Rudolf-Wissell-Strasse 28A Goettingen , NDS, 37079 GermanySingle-domain antibody discovery services Our experience combined with proprietary technologies provides an excellent choice for your nanobody discovery projects. The NanoTag Biotechnology discovery workflow is highly customizable to the needs of your project, ranging from complex counter selections steps, promoting conformation-specific epitopes, special salt and pH working conditions for binding, and other screening variations that have been carried out successfully in our facility.