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Atlanchim Pharma

3 RUE ARONNAX 44800 SAINT HERBLAIN FRANCEATLANCHIM PHARMA is a CRO which offers multi-step organic synthesis of complex molecules from few milligrams to several gram scale. The scientific team of ATLANCHIM PHARMA offers you all its experience and professionalism to move your projects forward. We can work on: Custom-made fine chemicals Isolation, Structural identification and synthesis of impurities formed during synthesis of an API Stable isotope labeling (D, 13C, 15N, 34S) Our expertise: Heterocycle chemistry Carbohydrate chemistry/Glucuronides Nucleoside chemistry Steroid chemistry Phosphorus and Sulfur chemistry Organometallic chemistry

Atlanchim Pharma

3 Rue Aronnax Saint-Herblain, 44800 FranceATLANCHIM PHARMA is a CRO which offers multi-step organic synthesis of complex molecules from few milligrams to several gram scale. The scientific team of ATLANCHIM PHARMA offers you all its experience and professionalism to move your projects forward. We can work on: Custom-made fine chemicals Isolation, Structural identification and synthesis of impurities formed during synthesis of an API Stable isotope labeling (D, 13C, 15N, 34S) Our expertise: Heterocycle chemistry Carbohydrate chemistry/Glucuronides Nucleoside chemistry Steroid chemistry Phosphorus and Sulfur chemistry Organometallic chemistry

Anadiag

16 Rue Ampere F-67500 Haguenau FranceANADIAG Group is a French Contract Research Organization (CRO) created in 1989 and located in Alsace, the heart of Europe. Specialized in plant protection products registration, the Group offers a wide range of expertise and services to support Global partners in their European registration projects. During these last 25 years, the Group has grown to a workforce of 150 across 12 countries engaged in various areas, such as field trials, chemical analysis, regulatory dossiers, project management, etc. With subsidiaries covering almost 80% of the European plant protection products market by value, ANADIAG Group is one of the leading agrochemical CRO with an extended field trial network across Europe. Having reached a turnover of 17 Million Euros in 2013, ANADIAG Group CEO, Eric Puy expects the future to remain both exciting and challenging! He continues to believe and invest in the Group slogan “Breadth of coverage, Depth of knowledge”. To satisfy our customers we offer an excellent quality service to develop customized and long-term partnerships whilst maintaining an ethical and confidential approach.

AD’HOC RESEARCH

34 Quai Charles De Gaulle 69006 - LyonFounded in 1992, Ad'hoc Research is a full-service research firm that uses tailored methods to conduct research and fieldwork in France and internationally. Its sector-specific teams are experts in qualitative and quantitative methodologies, whether we are collecting information face-to-face, by telephone or online. Our way of working is to provide innovative survey methods, high-tech analysis and create a relationship based on trust to achieve our goal: supply truly meaningful information to our clients.

Adscientis - DUPLICATE

10 rue Alfred Kastler 68310 WITTELSHEIM FranceAdscientis offers inverse gas chromatography (IGC) services.

Adscientis - DUPLICATE

Wittelsheim, Alsace-Champagne-Ardenne-Lorraine, 68310 FranceAdscientis offers inverse gas chromatography (IGC) services.

Adscientis

1 rue Alfred Kastler Wittelsheim, Alsace, 68310 FranceAdscientis is a company specialized in Inverse Chromatography especially in Gas Chromatography, surface property studies, characterization, and material quality services. This technique offers a precise characterization of the interaction of materials and their surfaces. It determines surface energy and measures different surfaces and bulk proprieties of solid materials (powders, fibres etc). Adscientis fabricates and sells a sets of robotised solution allowing the independent process of Inverse Chromatography directly in the entreprises.

Ardeche Lamas

Route des Gorges Quartier Costes Chaudes 07700 SAINT REMEZELe lama comme une oeuvre d’art! plus de vingt ans de passion ont conduit « Ardèche Lamas » à rassembler l’une des plus prestigieuses « collection » de lamas. En 2008 et 2009, deux importations viennent enrichir notre pléiade de champions. Parmi ces nouveaux venus, des lamas de types « suris ». Déjà vénérés par les incas pour leur laine considérée comme un fabuleux trésor de la nature, ces lamas sont d’une extrême rareté. Aspects historiques, scientifiques, écologie, vie sociale, tendresse et caresses, respect et douceur…voici ce que nous souhaitons vous faire partager.

AGROLIS Consulting

185 Rue André Ampère L'Isle-sur-la-Sorgue, Provence-Alpes-Côte d'Azur, 84800 France

ABCell-Bio

5 rue Henri Auguste Desbruères Evry, Ile-de-France, 91030 FranceWHO ? Abcell-bio is a French biotechnology company which provides a reliable source of human primary cells isolated from perinatal tissues and adequate culture media. WHAT ? Abcell-bio is specialized in production of: • Hematopoietic Cells isolated from cord blood or peripheral blood: CD34+ Hematopoietic Progenitors, MonoNuclear Cells from cord blood (MNC), Peripheral Blood Mononuclear Cells (PBMC) • Endothelial cells isolated from umbilical cord or cord blood: Endothelial Progenitor Cells (EPC), Human Umbilical Vein Endothelial Cells (HUVEC), Human Umbilical Artery Endothelial Cells (HUAEC) • Cell Culture Media: production of cell culture media dedicated to human primary cells HOW ? Abcell-bio has a unique expertise: the company controls the entire process from blood collection in maternity wards to the production of high-quality cells in dedicated laboratory facilities Thanks to its expertise, Abcell-bio makes your research faster thanks to: • A close partnership with maternity wards • Regulatory compliance (legal authorization, ethical compliance) • High-quality cells (purity, serological testing, viability, characterisation) adaptable to customers’ needs (quantity, HLA genotyping) • Reliable source of cells • Personalised after-sales services carried out by scientists Please contact us for more information at contact@abcell-bio.com

ABCell-Bio

5 Rue Henri Auguste Desbruères Évry, Île-de-France, 91030 FranceWHO ? Abcell-bio is a French biotechnology company which provides a reliable source of human primary cells isolated from perinatal tissues and adequate culture media. WHAT ? Abcell-bio is specialized in production of: • Hematopoietic Cells isolated from cord blood or peripheral blood: CD34+ Hematopoietic Progenitors, MonoNuclear Cells from cord blood (MNC), Peripheral Blood Mononuclear Cells (PBMC) • Endothelial cells isolated from umbilical cord or cord blood: Endothelial Progenitor Cells (EPC), Human Umbilical Vein Endothelial Cells (HUVEC), Human Umbilical Artery Endothelial Cells (HUAEC) • Cell Culture Media: production of cell culture media dedicated to human primary cells HOW ? Abcell-bio has a unique expertise: the company controls the entire process from blood collection in maternity wards to the production of high-quality cells in dedicated laboratory facilities Thanks to its expertise, Abcell-bio makes your research faster thanks to: • A close partnership with maternity wards • Regulatory compliance (legal authorization, ethical compliance) • High-quality cells (purity, serological testing, viability, characterisation) adaptable to customers’ needs (quantity, HLA genotyping) • Reliable source of cells • Personalised after-sales services carried out by scientists Please contact us for more information at contact@abcell-bio.com

ANAQUANT

5 Rue de la Doua Villeurbanne, Auvergne-Rhône-Alpes, 69100 FranceANAQUANT is a CRO dedicated to customized method development for proteins and peptides analysis. Our goal is to support our partners through their full R&D worflow. We are expert in method development for proteins and peptides analysis by LC-MS. We performed method development on any endogenous proteins, biomarkers, biologics but also vaccines or any compounds based on amino acids. We also developed a complete service offer HCP Profiler dedicated to HCP identification and quantification, allowing batch and bioprocess characterisation and comparison.

ANAQUANT

5 rue de la doua Villeurbanne, Rhone, 69100 FranceANAQUANT is a CRO dedicated to customized method development for proteins and peptides analysis. Our goal is to support our partners through their full R&D worflow. We are expert in method development for proteins and peptides analysis by LC-MS. We performed method development on any endogenous proteins, biomarkers, biologics but also vaccines or any compounds based on amino acids. We also developed a complete service offer HCP Profiler dedicated to HCP identification and quantification, allowing batch and bioprocess characterisation and comparison.

Amatsigroup

Parc de Génibrat Fontenilles, 31470 FranceAmatsigroup is a CDMO (Contract Development and Manufacturing Organization) offering services in preclinical and clinical phases of drug development for human and veterinary use.

ACEPP entreprise

196 avenue de Thiers - CS 20342 LYON cedex 06, 69455 France"We are architects of innovative technological and digital engineering solutions" ACEPP, a process specialist, works with the main players in the Life-Science, Environmental, Nuclear and Oil& Gas sectors. Thanks to our expertise in all types of engineering as well as in project management with our PMO offer, ACEPP improves the efficiency of our clients' projects. Our specialized resources supports you in all the phases of your most complex projects. Our integrated R&D centre also enables us to propose solutions related to Data Science, Data Engineering, Machine Learning and Imaging Deeplearning.

Agro-Bio

2, The Alley Chavannerie La Ferte Saint Aubin, 45240 FranceAgro-Bio (sub-subsidiary of the diagnostics in vitro company Stago) is one of the French pioneer in the development and production of CUSTOM ANTIBODIES since 1975. REACTIVITY, high QUALITY service at COMPETITIVE PRICING as well as building long term and confidence-based collaboration with our customers are our key engagements. Our mission is to support each client to implement the best strategy for each project. Agro-Bio provides its expertise for public research teams, CRO's, biotech and IVD companies as well as renowned Big-Pharma (ISO9001/ISO13485/CIR). Agro-bio offers a wide range of fully customized services: BIOANALYTICS - ADA reference samples for your immunogenicity tests - Anti-idiotypic and/or neutralizing antibodies for PK/PD and potency tests - BIACORE : afffinity, receptor binding, cynomolgous vs human - Antibody characterization: stability, affinity, epitope mapping, sequencing, aggregation BIOPRODUCTION - Selection and validation of generic assays (preclinical and clinical phase I and II) • Performance study of the generic HCPs ELISA • Determination of ELISA suitability and accuracy: dilutional linearity, specificity, spike recovery, LOD / LOQ • Coverage assessment of the antibodies of the generic HCPs ELISA (Required by the reglementary authorities) - Development of a process specific (required from phase III) • Bulk production/purification of process-specific HCP polyclonal antibodies on rabbit, goat or chicken. • Validation of HCP antibodies: coverage assessment by 2D-DIBE (fluorescent based) and purification by affinity on HCP antigen • Development and validation of process-specific HCPs ELISA kits • Manufacturing of HCP ready-to-use ELISA kits - Mass spectrometry analysis can be implemented as an orthogonal method. IN VITRO DIAGNOSTICS - Large scale mAb production (from mg to 10g-scale) - Large scale pAB production (goat, rabbit, guinea pig, chicken, mice & rat) - mAb & pAb development - BIACORE® analysis: affinity, antibody pairs, stability DISCOVERY - Immunogen design & generation - Target validation and Proof-of-concept antibody-tools - R&D antibodies: mAB & pAb multi-species - Conjugation, Fragmentation, Sequencing

Active Biomarkers

60 F Avenue Rockefeller BIOSERRA 2 Building - 3rd floor Lyon, 69008 FranceActive Biomarkers is an integrated bioanalytical laboratory offering multiple in-vitro immunology services: Pharmacokinetics, Immunogenicity, Receptor Occupancy assays, and soluble/cellular biomarkers monitoring. Operating in BSL2 facilities, and GCLP/ISO 9001:2015 environment, the company currently employs 30 people bringing a wealth of experience in the development, validation, and implementation of analytical methods. Its know-how is recognized in 4 major therapeutic areas: oncology, infectious diseases, inflammatory pathologies, and neurodegenerative diseases. Beyond its state-of-the-art flow cytometry and ELISpot capabilities, Active Biomarkers offers the broadest panel of immunoassay technologies in Europe, ranging from standard ELISA to multiplexed methods such as Luminex, SP-X, Gyros or ELLA systems, and ultra-sensitive technologies such as MSD or Simoa HD-1.

Active Biomarkers

321 Avenue Jean Jaurès Lyon, 69007 FranceActive Biomarkers is an integrated bioanalytical laboratory offering multiple in-vitro immunology services: Pharmacokinetics, Immunogenicity, Receptor Occupancy assays, and soluble/cellular biomarkers monitoring. Operating in BSL2 facilities, and GCLP/ISO 9001:2015 environment, the company currently employs 30 people bringing a wealth of experience in the development, validation, and implementation of analytical methods. Its know-how is recognized in 4 major therapeutic areas: oncology, infectious diseases, inflammatory pathologies, and neurodegenerative diseases. Beyond its state-of-the-art flow cytometry and ELISpot capabilities, Active Biomarkers offers the broadest panel of immunoassay technologies in Europe, ranging from standard ELISA to multiplexed methods such as Luminex, SP-X, Gyros or ELLA systems, and ultra-sensitive technologies such as MSD or Simoa HD-1.

AIXIAL

4 Rue Barthelemy Danjou Boulogne-Billancourt, Île-de-France, 92100 FranceAIXIAL is the CRO of Alten Group, a global leader in Engineering and High Added-Value services with 30 000 employees worldwide and revenues of 2 Billion Euros in 2017 (www.alten.com). With more than 500 people and a strong and steady growth of 20%, AIXIAL is among the Top 5 European full-services CROs with a planned extension in the USA. Our main Departments are Clinical Operations, Clinical Data Science, Vigilance & Medical Information, Regulatory Affairs & Quality Management, Real-World Data. Our philosophy is to be a flexible and agile Digital Solution Provider for our clients, by proposing taylor-made solutions to address each specific situation of a client rather than always applying the same processes and solutions. - Flexibility in our engagement models: Workpackages, Functional Services Platforms, Consultancy - Optimization of your timelines and budget, Mitigation of risks: Study methodology, feasibility studies (countries, sites), Risk-Based Monitoring, Patient recruitment and retention - Digitalization: CTMS, eTMF, eISF (Veeva), eICF, eCRF, ePRO

Antagene

6 allée du Levant CS 60001 La tour de Salvagny, 69890 FranceAntagene offers molecular biology, antibody production, chromatography, spectrometry, and assays.

Axyntis

45 rue de Pommard, F-75012 Paris, FranceAxyntis offers subcontracting services for markets such as life sciences, fine specialty chemicals (electronics, etc.) and coloring agents.

AlpX

71 avenue des Martyrs Grenoble, 38000 FranceALPX is the newest EMBL Spin-off providing structural biology services to accelerate the drug discovery process. Our fully automated Protein-to-Structure pipelines are based on unique Technologies developed at EMBL HTX lab: CrystalDirect™ and CRIMS.

Abliance

21 quai du Clos des Roses, 60200 Compiègne, FRANCEAbliance owns key technologies and constantly innovates to develop next generation antibodies. Our team of experts closely works with research laboratories, diagnostic industry, clinical research and biopharmaceutical industry actors to understand the needs of each purpose, its regulatory environment and economic constraints. Abliance provides antibodies that perform in their application by designing unique solutions.

Abliance

Compiègne, Hauts-de-France, 60200 FranceAbliance owns key technologies and constantly innovates to develop next generation antibodies. Our team of experts closely works with research laboratories, diagnostic industry, clinical research and biopharmaceutical industry actors to understand the needs of each purpose, its regulatory environment and economic constraints. Abliance provides antibodies that perform in their application by designing unique solutions.

Aureus Sciences

174 Quai de Jemmapes 75010 Paris – FranceAureus Sciences provides a range of scientific knowledge solutions enabling biopharmaceutical companies to better understand the relationships of biological targets to compounds under evaluation.

Alltech

ZA La Papillonnière Rue Charles Amand 14500 Vire FranceFounded in 1980 by Irish biochemist and entrepreneur Dr. Pearse Lyons, Alltech is a leading global biotechnology company whose mission is to improve the health and performance of people, animals and plants through natural nutrition and scientific innovation. We pursue this mission guided by what we call the ACE principle, our promise that in doing business we have a positive impact on the Animal, the Consumer and the Environment. Animal Health Our core business improves animal health and performance by adding nutritional value to feed, naturally, through Alltech’s innovative use of yeast fermentation, enzyme technology, algae and nutrigenomics, which studies the impact of nutrition at the genetic level. Our technologies and support programs enable farmers to realize greater efficiency, profitability and sustainability on their farms. Alltech Crop Science Our Alltech Crop Science division complements our animal nutrition business by focusing on improving the health of crops. Our technologies enable us to improve the productivity of the field, in terms of yield quality and quantity, and to enhance nutrition beginning with the soil and the seed. Human Health We believe scientific innovation in animal and crop sciences is part of a much more important story, that of human health. Healthier animals and crops, nurtured naturally through Alltech’s nutritional solutions, affect human well-being. For example, fruits, vegetables and animal proteins have become less nutrient-rich in the past half-century. From fish to oranges, you need to eat more today to get the same nutritional value. Our work within animal and crop sciences is restoring value and also exploring ways to naturally enrich foods through improving the animal diet or crop produced. For example, laying hens fed a diet rich in Alltech’s algae produce eggs enriched with DHA omega-3, an essential nutrient for human cognitive development and health at all ages.

AXO Science

31 rue du Mail Lyon, 69004 FranceAXO Science offers microarray spotting services.

BioProtein Technologies

Domain de Vivert Batiment 220 78350 Jouy-en-Josas, FranceBioProtein Technologies offers protein purification, pharmacology, and human therapeutic proteins and vaccines in transgenic rabbit milk.

BioProtein Technologies

Lyon, Auvergne-Rhône-Alpes FranceBioProtein Technologies offers protein purification, pharmacology, and human therapeutic proteins and vaccines in transgenic rabbit milk.

BioClinica

60 Avenue Rockefeller F-69008 Lyon, FranceBioClinica offers imaging services.

A.S.C.

Les Chevrières 71570 CHAINTRÉ FRANCEA.S.C. Crop Protection and A.S.C. Biocides are consulting companies expert in regulatory chemistry. Our mission is to inform you about the regulation that applies to your activity, and to help you providing the Authorities with the necessary dossiers in order to be authorised to produce, import or sell your substance or product, either new or existing. Our teams currently pool 23 scientists, whose backgrounds cover all areas related to chemical risk assessment: physico-chemistry, analysis, toxicology, ecotoxicology, biological efficacy, etc.

Addex Therapeutics

12 Chemin des Aulx Plan-les-Ouates, GE, 1228 SwitzerlandAddex Therapeutics is pioneering discovery and development of an emerging class of oral small molecule drugs, called allosteric modulators, which can be exquisitely selective for their intended target and confer significant therapeutic advantages over conventional “orthosteric” small molecule or biological drugs.

ARVALIS - Institut du Vegetal

3 rue Joseph et Marie Hackin 75016 PARISARVALIS - Vegetable Institute For technological agriculture, efficient and sustainable resolutely Improve farm competitiveness, create opportunities, improve the profitability of production and chains and satisfy consumers and citizens are the objectives ARVALIS Institute plant. The expertise to farmers and industries A network of engineers and experts present on the national territory ARVALIS Institute plant, applied research organization, product technical and economic references and directly applicable in the agricultural production systems. Research stations, experimental sites, farms application, laboratories, the Institute has 35 sites located throughout the national territory. The teams are piloting studies at different levels of scale: - the plant: varietal characterization, development of biotechnologies - the plot: technical route; protection; nutrition; implantation techniques, crop protection products or applications. - exploitation and watershed: risk management point and diffuse pollution, organic status and soil fertility, biodiversity management, greenhouse gases greenhouse effects and conducted rotations, operating economics and competitiveness. The Institute's jurisdiction covers production techniques, harvesting, storage and preservation as well as the qualitative aspects of productions for all opportunities. The institute offers training and disseminates information through a strong presence in the press or on its own information channels: Agricultural Outlook, ARVALIS CETIOM information, ARVALIS.fr, information meetings and symposia, pamphlets. It also offers farmers and technicians operational tools, often computerized, for the conduct of crops.

ArisGen

Chemin des Aulx, 14 1228 Plan-les-Ouates, Geneva (Switzerland)ArisGen is a research-based team dedicated to innovation in the field of drug delivery as a way to improve health.

Aureus Pharma

174 Quai de Jemmapes Paris 75010 FranceAureus Pharma offers custom databases, training, and database management products.

Agate Bioservices

Alès, Occitanie FranceAgate Bioservices offers cloning, plasmid purification, mutagenesis, PCR, recombinant protein production and purification services.

Antellis

Impasse Palayré Toulouse, 31100 FranceAntellis is an independent analytical laboratory specialising in elemental analysis by mass spectrometry (ICP-MS) providing services for Pharmaceuticals, Cosmetics, Chemicals, Agro Food Industry, and Environment, for routine analyses or contract research studies.

Aptys Pharmaceuticals

Saint-Beauzire, Auvergne-Rhône-Alpes, 63360 FranceAptys Pharmaceuticals offers contract service for formulation development, analytical development, consulting and support.

AnimaScope

St. Vincent de Mercuze, Grenoble, FranceAnimaScope offers preclinical in vivo imaging, including MRI, ultrasound, tomography, and optical imaging.

AnimaScope

Grenoble, Auvergne-Rhône-Alpes FranceAnimaScope offers preclinical in vivo imaging, including MRI, ultrasound, tomography, and optical imaging.

AJC Pharma

18, rue Troyon 75017 PARIS FranceAJC Pharma manufactures pharmaceutical forms of dry powder, granules, uncoated tablets, film-coated tablets and capsules.

Aix En Lama

1950 Chemin de la Guiramande Aix-en-Provence, Provence-Alpes-Côte d'Azur, 13080 FranceAix-en-Lama is an association designed to make known the Lama, emblematic animal of South America and also to make you aware of animal mediation thanks to our educational farm.

Alsace Biovalley

Illkirch, Alsace-Champagne-Ardenne-Lorraine FranceAlsace Biovalley provides support for R&D and technology transfer.

ANS Biotech

20-22 rue Henri Goudier Riom, Auvergne - Rhône-Alpes, 63200 FranceANS Biotech is an independent preclinical Contract Research Organization (CRO) fully dedicated to the pharmacology of pain. The company offers its clients a unique combination of expertise in the fundamentals of pain pharmacology and a proven record of R&D program management for new and innovative analgesics. Our mission is to collaboratively support the drug discovery and development efforts of human and animal health companies by offering: > Unique early screening services to profile your drug candidates, > Tailored solutions for the management of your research projects, > A growing list of clinically relevant and predictive disease and efficacy in vivo models of pain, > Comprehensive consulting services based on an extensive industrial experience. As a close Pharma and Biotech partner, ANS Biotech commits itself to providing cost-effective preclinical pharmacology services performed to the highest ethical and quality standards. Our validated and customized behavioral studies can help to quantify the efficacy of your compounds before they move into clinic by: > Establishing proof of concept & mechanism of action for drug candidates, > Achieving the critically important positioning of these agents within precise therapeutic categories (cancer pain, neuropathic pain, visceral pain, …), > Benchmarking drug candidates with clinical gold standards. We aim to act as an extension of your scientific team wherever you are located around the world, helping you to optimize and accelerate the development of your drug candidates.

ANS Biotech

20 Rue Henri Goudier Riom, Auvergne-Rhône-Alpes, 63200 FranceANS Biotech is an independent preclinical Contract Research Organization (CRO) fully dedicated to the pharmacology of pain. The company offers its clients a unique combination of expertise in the fundamentals of pain pharmacology and a proven record of R&D program management for new and innovative analgesics. Our mission is to collaboratively support the drug discovery and development efforts of human and animal health companies by offering: > Unique early screening services to profile your drug candidates, > Tailored solutions for the management of your research projects, > A growing list of clinically relevant and predictive disease and efficacy in vivo models of pain, > Comprehensive consulting services based on an extensive industrial experience. As a close Pharma and Biotech partner, ANS Biotech commits itself to providing cost-effective preclinical pharmacology services performed to the highest ethical and quality standards. Our validated and customized behavioral studies can help to quantify the efficacy of your compounds before they move into clinic by: > Establishing proof of concept & mechanism of action for drug candidates, > Achieving the critically important positioning of these agents within precise therapeutic categories (cancer pain, neuropathic pain, visceral pain, …), > Benchmarking drug candidates with clinical gold standards. We aim to act as an extension of your scientific team wherever you are located around the world, helping you to optimize and accelerate the development of your drug candidates.

Ambiotis

3 Rue des Satellites Toulouse, Occitanie, 31400 FranceAmbiotis is a pre-clinical CRO focused on inflammation and with a worldwide recognized expertise on the resolution phase of inflammation. Ambiotis provides state-of-the-art bioassay and analytical services to detect and quantify specific biomarkers of the different phases of inflammatory/resolution process, to bring proof of concept of ingredients/molecules efficacy and to establish the mechanism of action in an innovative way. Ambiotis also provides lipidomics service, especially for the quantification of the main cutaneous lipids (ceramides, wax esters, squalene, cholesterol, cholesteryl ester, free fatty acids, total fatty acids...)

ABC Farma

C/ Pau Claris, 167 Pral. 2 Barcelona, B08037 SpainABC Farma Internacional specializes in cosmetic, transdermic and hydrogel patches.

Amarok Biotech

3 Impasse du Grand Jardin 35400 Saint-Malo FranceAmarok Biotech is a Contract Research Organization that provides services in biological reagents, automated biological analysis, flow cytometry, and biomarkers validation. Our private laboratories are designed for R&D outsourcing

Athena Drug Delivery Solutions

106 Bureaux de la Colline Bat F2, 92213 Saint Cloud, FranceAthena provides development services, dossier licensing, and scientific support.

Athena Drug Delivery Solutions

Saint-Cloud, Île-de-France, 92210 FranceAthena provides development services, dossier licensing, and scientific support.

ArtImmune

FranceArtImmune offers analysis in animal models of lung inflammation, neurological disease, and infectious disease models.

ArtImmune

13 Avenue Buffon Orléans, 45000 FranceArtImmune offers analysis in animal models of lung inflammation, neurological disease, and infectious disease models.

Advanced BioScience Laboratories

317 Avenue Jean Jaurès Lyon, Auvergne-Rhône-Alpes, 69007 FranceABL is a CRO/CMO with a full range of in vitro and ex vivo testing services coupled with cGMP manufacturing to accelerate candidate vaccines, biotherapeutics, and viral vectors into the clinic.

AMYLGEN

2196 Boulevard de la Lironde Montferrier-sur-Lez, Occitanie, 34980 FranceAmylgen is a preclinical CRO offering a unique combination of validated in vivo models and a full range testing. Fast and predictive screening of the effects of drugs and nutraceuticals on brain health.

AMYLGEN

2196 Boulevard de la Lironde Parc Scientifique Agropolis 2 Montferrier sur Lez, 34980 FranceAmylgen is a preclinical CRO offering a unique combination of validated in vivo models and a full range testing. Fast and predictive screening of the effects of drugs and nutraceuticals on brain health.

Alpha MOS

20, avenue Didier Daurat 31400 Toulouse - FranceAlpha MOS provides chemical analysis, odor monitoring solutions, and electronic noses, tongue, and eyes.

Alpha MOS

Toulouse, Languedoc-Roussillon-Midi-Pyrénées FranceAlpha MOS provides chemical analysis, odor monitoring solutions, and electronic noses, tongue, and eyes.

American Elements

69004 Lyon, FRANCEAmerican Elements' catalog of more than 15,000 products makes it the world’s largest metals and chemicals manufacturer devoted exclusively to advanced materials in industrial bulk and laboratory/research quantities. Our development programs have been a key source for academic and corporate research and new product development for over two decades. Fundamental expertise in the properties, applications, and cost-effective manufacturing of advanced and engineered materials, including ultra high purity refining (99.999%) and nanoscale materials, allows us to meet the needs of thousands of global manufacturers (including over 30% of the Fortune 50), all U.S. national laboratories and military branches, universities throughout the world, and customers in a wide range of industry fields, such as energy, electronics, aerospace, defense, automotive, optics, green technology, and pharmaceuticals. American Elements also produces customer proprietary formulations from our network of production facilities worldwide. Our dedication to the highest possible quality control and lot-to-lot consistency is equally matched by our goal to be at the forefront of creating a sustainable planet that continually moves towards improving the human experience for all mankind. Invention is the means of achieving this goal, and American Elements employees are driven to engineer and deliver the basic raw materials of innovation in a socially responsible manner. All we ask of our customers and partners is reflected in two simple words... Now Invent™

Assitance Publique Hopitaux de Paris

Paris, FranceLa recherche et l’enseignement font partie de nos missions. Nous faisons de la recherche pour améliorer en permanence les soins et mettre en place de nouveaux traitements. En France, la moitié de la recherche clinique s’effectue dans les hôpitaux de l’AP-HP. La recherche vous permet de bénéficier des traitements les plus récents et de participer, aux côtés de nos médecins et soignants, aux progrès de la médecine. Dans un hôpital universitaire, vous avez la possibilité de participer à un « essai clinique » ou à un « essai thérapeutique », mais seulement avec votre accord explicite. L’essai auquel vous participez est placé sous le contrôle d’un comité d’éthique et vous signez un « consentement.

Assitance Publique Hopitaux de Paris

Paris, Île-de-France FranceLa recherche et l’enseignement font partie de nos missions. Nous faisons de la recherche pour améliorer en permanence les soins et mettre en place de nouveaux traitements. En France, la moitié de la recherche clinique s’effectue dans les hôpitaux de l’AP-HP. La recherche vous permet de bénéficier des traitements les plus récents et de participer, aux côtés de nos médecins et soignants, aux progrès de la médecine. Dans un hôpital universitaire, vous avez la possibilité de participer à un « essai clinique » ou à un « essai thérapeutique », mais seulement avec votre accord explicite. L’essai auquel vous participez est placé sous le contrôle d’un comité d’éthique et vous signez un « consentement.

AltraBio

30 rue Pré Gaudry Lyon, 69007 FranceAltraBio is an R&D company expert in analysis and interpretation of biomedical data in both preclinical and clinical development. Particularly focused on OMICS and Flow/Mass cytometry technologies, the goal of AltraBio is to unlock the value captured in large scale datasets generated in life science experimental studies. Founded by a team of highly skilled professionals with experience at the interface of biology, medicine, statistics and informatics, AltraBio is well positioned to understand the complex data problems encountered in the life science industry and to address them by creating state-of-the-art techniques and tools. AltraBio team has extensive experience in statistical modeling, machine learning, data mining and software/database design, as well as educational and professional background in biomedical sciences and medicine. In addition to designing and implementing computational solutions, they have the knowledge and skills to interpret the results of quantitative analysis in the context of current biomedical knowledge.

Aguettant

1, rue Alexander Fleming LYON 69007 FRANCEAguettant offers device development, aseptic processing, manufacturing, and filling services.

Antineo

Faculté de Médecine 8 avenue Rockefeller Lyon, 69008 FranceAntineo performs preclinical services in oncology. We offer in vitro and in vivo preclinical services. Our most sought-out service are our original tumour models displaying acquired resistances to immunotherapies (CDX and syngeneic tumour model).

AXENIS

28, rue du Docteur Roux Paris, 75015 FranceAXENIS is a service company using humanized mice as preclinical models in immunology, for the pharmaceutical industry, biotechnology companies and academic research.

Albert Einstein College of Medicine YU Zebrafish Core

Chanin 523 Overview Zebrafish is a powerful system for studies of embryogenesis and to investigate mechanisms underlying human diseases. The zebrafish is particularly well suited to study complex and acquired diseases and to identify new disease genes owing to its genetic tractability, transparency of the organism, and the ease of conducting chemical screens to identify diagnostic and potential therapeutic targets. Moreover, the high degree of genetic conservation renders translation between fish and mammals a possibility. For example, this model system can be used to validate and characterize genome-wide association study (GWAS) candidates through gain of function and loss of function approaches. For loss of function analysis the candidate, the gene of interest can be transiently knocked down or stable mutant alleles can be generated through reverse genetic mutagenesis approaches. The phenotypes produced by the normal and mutant versions can provide an indication of the gene’s function in development and disease. The Einstein Zebrafish Core was established to facilitate this type of analysis.

Atlantic Bone Screen

3 rue aronnax NANTES, 44821 FranceATLANTIC BONE SCREEN is a French CRO focusing on bone and joint diseases and on bone diseases from tumor origin. ATLANTIC BONE SCREEN puts at its customers’ disposal a unique preclinical platform with a wide range of competitive in vitro and in vivo assays as well as histology and imaging services in order to screen and qualify your drug candidates, nutraceuticals and biomaterials. osteoporosis - osteoarthritis - bone cancer - bone metastases - histology - microCT biomaterials

ASCOPHARM Groupe NOVASCO

56 Rue de Landres 75008 ParisASCOPHARM and the NOVASCO Group represent one of the most proactive Contract Research Organization in the field of Clinical Research in Europe. Founded in 1995 the original company, ASCOPHARM has now been raised to a full clinical and medical service group. Information on activities and structures can be found in History section and Global Group. The company has now specificities and expertise in a number of aspects of clinical research and post marketing support. Apart from standard services that other company may also offer, ASCOPHARM and the NOVASCO Group have raised up expertise in certain therapeutic fields (Oncology, Transplant, Immune modulators, Rheumatology, Cardiovascular disease…). The Group has also developed original services for site management and support (Site CRA services). Together will all services offered, ASCOPHARM has strongly developed its expertise in Information Technologies and Computer Software. Original tools have been developed (eCRF, Project Management tools, etc…) and an IT company has been integrated to the group. General structure is developed in Global Group while services are described in other sections.

Atlanbio

Route de Saint-André des Eaux Z.I de Brais - B.P 40309 Saint Nazaire, 44605 FranceAtlanbio offers chromatography and immunochemistry services.

Biochemikon

17, Rue Olof Palme 94000 CRETEIL FranceWe offer our customers a unique panel of assays aimed at measuring different cell metabolism markers. These markers (enzymes, substrates,…) will allow either a global exploration or a specific analysis of a narrower part of cell metabolism. Using our performant technology, it becomes possible to evaluate the respective impact of each metabolism in cell behavior and to compare precisely cell function in a longitudinal manner. Biochemikon services cover the full spectrum from standard methods through to cutting-edge custom approaches developed using latest biological insights and specially developed new assays.

Bellen

44 Rue Boson Vienne, 38200 FranceBellen Chemistry, established in 2007, originally focused on the design and development of hundreds of novel heterocycles. Over a number of years, our innovative capabilities and reliable performance were gradually becoming more recognized in the marketplace, and our customers encouraged us to develop CRO/CDMO business with them. In order to provide better solutions for our customers, the company has undertaken three rounds of venture capital financing to support our dynamic growth. A manufacturing plant has been constructed in Shandong in addition to a new process R&D center in Shanghai since 2017, and the capital investment is also enabling the relocation of our R&D innovation center to a new site in Beijing by end of 2020. In the past 14 years, the company has grown from 6 employees to over 800 employees. In line with our global service commitment, we have also set up Bellen branches in the US, UK, Canada, France and Japan so as to provide better and faster services to our local customers. Today we provide project support to a variety of different customers, from innovative biotech to global giant pharmaceutical companies. Bellen is committed to continuing investing in innovation and state-of-the-art facilities to enable a one-stop-shop chemistry service platform, adding value to your project from library synthesis to API GMP manufactory.

Bforcure

14, rue de la Beaune Bâtiment C, 2ème étage Montreuil, Ile-de-France, 93100 FranceBforcure provides services (PCR, qPCR, RT-PCR, RT-qPCR, multiplex PCR) using existing assays and custom designed assays. Services are performed on standard qPCR machines or assays can be optimized to work on our ultra fast machines.

Biosolve chemicals (duplicate)

20 rue Roger Husson Dieuze, 57260 FranceBiosolve is specialised in the production and distribution of high purity solvents, and supplies the pharmaceutical industry, hospital analytical laboratories, universities, research institutes, environmental analytical laboratories and associated industries.

BioXtal

227, Route de la Chapelle 74540 SAINT FELIX - FranceWith 15 years' experience in the field of structural biology, our team confidently tackles the new challenges brought by our customers. Our scientists' dedication and creativity are our trademark. This allows Bioxtal to deliver more than the expected results whatever the challenges may be. Our determination allows us to offer a "no result- no fee" delivery i.e. we only charge if work is 100% completed.

Bio-Logic

1 rue de l'Europe Claix FR-38640 FranceBio-Logic offers design and manufacturing for rapid kinetics, spectroscopy, physiology, neuroscience, electrochemistry, and fuel cells.

Bio-Logic

Claix, Auvergne-Rhône-Alpes FranceBio-Logic offers design and manufacturing for rapid kinetics, spectroscopy, physiology, neuroscience, electrochemistry, and fuel cells.

Biogalenys

9 Rue de Pacy Miserey, 27930 FranceBiogalenys offers permeability studies in rat and rabbit as well as in vitro skin, intestine, cornea, mucous membrane and nail models.

B Lands Consulting

World Trade Center 5 Place Robert Schuman - BP 1516 38025 Grenoble, FranceB-Lands Consulting provides consultancy services for compliance to EU, US, and China regulations.

BioExigence

8 Rue Alfred de Vigny Besançon, Bourgogne Franche-Comté, 25000 FranceBIOEXIGENCE, Private Research laboratory, created in 2004 thanks to the French law on research and innovation, offers services of high technological level and works for pharmaceutical and cosmetic laboratories. Studies are performed from specific cell lines, obtained after biopsies from leg ulcer, keloids, striae distensia or wrinkles. We are able to obtain cell lines with specific age thanks to collaborations with hospital or private clinics, A leg ulcer that does not heal, the appearance of wrinkles or stretch marks ... Thanks to SKINBioTest, which offers services including in vitro tests on cell cultures and ex vivo tests on operative wastes, BIOEXIGENCE is able to provide proofs of efficacy of a medicine or cosmetic actives.

BIO-HC

Parc d'Activités de Magellan 14 rue Claude Chappe FR - 33600 PessacBIO-HC is a privately-owned independant laboratory, created 1996 by 4 scientists. Specialised in the assessment and validation of your cosmetic and toiletry products. TOLERANCE and EFFICACY of your products assessed in accordance with current regulations. From ACTIVE INGREDIENT to FINISHED PRODUCT, made-to-measure support through every stage of your product development.

Biotrial International Ltd

7-9 rue Jean-Louis Bertrand RENNES, 35000 FranceBiotrial offers in vivo studies and GLP safety pharmacology services.

Biocellvia

10 Rue Grignan Marseille, Provence-Alpes-Côte d'Azur, 13001 France Biocellvia has developed an expertise in compound validation assay based on digital imaging analysis. Our technology allows to measure the level of compound efficacy in a fully quantitative manner. Our automated analysis is more accurate, sensitive and reliable (100% reproducibility) and fully observer independent than any other technology on the market. As Proof of concept Biocellvia had the opportunity to collaborate with Boehringer Ingelheim in order to correlate and validate our IPF assay directly with some conventional methods such as the « Ashcroft scoring » and published in Plos One a common article. "Quantification of pulmonary fibrosis in a bleomycin mouse model using automated histological image analysis" http://www.biocellvia.com/2017/02/14/biocellvia-publication-quantification-pulmonary-fibrosis/ Biocellvia’s assay can lead you to a solid and clearer decision making on your drug compound based on robust data and accelerate your preclinical development, a conventional study (250 slides) takes a few hours. Our current validation assays portfolio : • IPF, idiopathic pulmonary fibrosis: the new validated reference in pulmonary fibrosis evaluation • COPD, chronic obstructive pulmonary disease: Emphysema: an innovative multi-parametric analysis • COPD, chronic obstructive pulmonary disease: Small airway remodeling: a unique comprehensive automated quantitative tool, peribronchial collagen included. • NASH/NAFLD : Fibrosis, steatosis, ballooning inflammation quantification • PAH, pulmonary arterial Hypertension. • Kidney Fibrosis

Biomeostasis

Actiparc 1 Bâtiment 6 Traverse de la Penne La Penne sur Huveaune, 13821 FranceBIOMEOSTASIS is a leading Preclinical CRO that offers in vivo research services in the fields of Metabolic, GI and Age-related Diseases. For over 11 years, we have been assessing the efficacy and mechanisms of action of products aiming at preventing and/or treating conditions such as Obesity, Diabetes, NAFLD/NASH, Cancer Cachexia, Inflammatory Bowel Diseases, Sarcopenia...

Boston Scientific - Boston Scientific, Research and Technology Center (RTC)

Parc Val Saint Quentin - Bâtiment H 2 Rue René Caudron 78960 Voisins-le-Bretonneux FranceThe Boston Scientific Corporation (abbreviated BSC) is a worldwide developer, manufacturer and marketer of medical devices whose products are used in a range of interventional medical specialties, including interventional radiology, interventional cardiology, peripheral interventions, neuromodulation, neurovascular intervention, electrophysiology, cardiac surgery, vascular surgery, endoscopy, oncology, urology and gynecology. Boston Scientific is primarily known for the development of the Taxus Stent, a drug-eluting stent which is used to open clogged arteries.[3] With the full acquisition of Cameron Health in June 2012, the company also became notable for offering a minimally invasive implantable cardioverter-defibrillator (ICD) which they call the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD).

Biotem

Parc d’activités Bièvre Dauphine 885 rue Alphonse Gourju 38140 Apprieu – FranceExpert in immunotechnology since 1980, BIOTEM is a Contract Research Organisation which provides high added value services for the development of custom monoclonal antibodies and immunoassays (ELISA & LFIA). Complying with ISO 9001:2008 Quality Standards, the company has been the privileged partner of more than 400 prestigious industrial and academic laboratories for their projects in fundamental research, development of improved diagnostics or generation of promising therapeutic tools. Based on a high level of expertise and exclusive technologies, BIOTEM implements the most relevant strategies for each project according to the client’s specifications. As a benefit, BIOTEM is keen to propose contracts with guaranteed results. From the generation of original monoclonal antibodies ̶ by hybridoma and Phage Display technologies ̶ through their production, characterisation (affinity & specificity determination, sequencing, stability studies,…) and immunoassay developments, BIOTEM offers a wide range of customised services.

Biotem

Parc d’activités Bièvre Dauphine 885 rue Alphonse Gourju Apprieu, 38140 FranceExpert in immunotechnology since 1980, BIOTEM is a Contract Research Organisation which provides high added value services for the development of custom monoclonal antibodies and immunoassays (ELISA & LFIA). Complying with ISO 9001:2008 Quality Standards, the company has been the privileged partner of more than 400 prestigious industrial and academic laboratories for their projects in fundamental research, development of improved diagnostics or generation of promising therapeutic tools. Based on a high level of expertise and exclusive technologies, BIOTEM implements the most relevant strategies for each project according to the client’s specifications. As a benefit, BIOTEM is keen to propose contracts with guaranteed results. From the generation of original monoclonal antibodies ̶ by hybridoma and Phage Display technologies ̶ through their production, characterisation (affinity & specificity determination, sequencing, stability studies,…) and immunoassay developments, BIOTEM offers a wide range of customised services.

BioCydex

1 rue Georges Bonnet Poitiers, 86000 France

BioQuanta

5, rue de labbé de lEpée Paris 75005 FranceBioQuanta offers molecular modeling, data generation, structure-activity prediction, target identification, optimization services, and toxicity prediction.

Biobanque de Picardie

CHU AMIENS - Avenue René Laënnec 80480 SALOUEL - FranceBiobanque de Picardie is located at the heat of the Amiens University situated one hour from Paris. It is a bank of biological samples and data dedicated for scientific research. Certified ISO 9001 and NFS 96-900, Biobanque de Picardie is an accredited Biological Resources Center providing quality and traceability services for establishment, conservation and use of biological samples collections. Biobanque de Picardie is a secure repository where biological samples are stored for medical and research purposes. These biological samples are linked to consenting patient relative data.

Bio4ward

87 Quai des Queyries 87, quai de Queyries Bordeaux, Nouvelle-Aquitaine, 33100 FranceThanks to its network of qualified experts from the industry, Bio4ward proposes custom solutions based on complementary skills addressing the needs of your project. Pharma, Biotech, Medical devices… Bio4ward supports start-ups and companies looking for high added value expertise on a temporary or long term basis. Bio4ward is a single point of contact for the support of start-ups and SMEs so that bio-entrepreneurs can focus on their core business, avoid the development pitfalls, and optimise value creation. Bio4ward is a unique combination of: The experience and professionalism from major companies. The start-up culture and pragmatism. To the service of innovative life sciences companies

Bertin Instruments

Parc d’activités du Pas du Lac 10 bis, avenue Ampère 78 180 Montigny-le-Bretonneux FranceBertin Instruments is a brand of CNIM Group, dedicated to innovative measurement and sampling solutions for key worldwide markets such as: Lab Equipment (sample preparation, air sampler) Nuclear Instrumentation (radon professional monitoring, environmental radiation monitoring systems, radiation portal monitors, health physics) Defense, Security and Safety / Oil & Gas (CBRN, gas detection, optronics) Our instruments allows our customers to measure, sample and detect invisible elements (DNA, gases, ionizing radiation, night concealed targets…). Our customized sales and R&D approach is based on: a product-specific and customer-centered organization a global presence with a wide network of local partners targeted markets where our engineers can stand out with technological excellency a high technical & scientific digital support

BAMBOO Research

37, boulevard Aristide BRIAND AIX EN PROVENCE, Bouches du Rhone, 13100 FranceBamboo Research is a full market research company offering both qualitative and quantitative methodologies. Our small team of senior consultants is dedicated to providing the most qualitative insights to allow the most efficient decision-making.

Biopredic International

Parc D'affaires la Breteche Bldg A4 Saint Gregoire, Ille et Vilaine, 35760 FranceBiopredic International provides human and animal primary cells, cell lines, and tissues for research, drug discovery, and drug development.

BIOTEK Agriculture

Route de Viélaines 10120 Saint Pouange, FRANCEn collaboration with companies specialising in plant protection and seed development, BIOTEK Agriculture conducts many studies required to check the qualities of plant protection products and seeds before they are marketed. In all phases of your projects and at all levels of your business, BIOTEK Agriculture can be of service to you.

BV Transgenic Services

FranceBV Transgenic Services offers embryology, genotyping, histology, and phenotyping services.

BrainPlotting

70 av. Marx Dormoy 92120 Montrouge FranceOur core business is the study of pharmacokinetics (PK) in the human brain. The molecules that we study can have CNS targets as well as peripheral targets.

Borochem

5 rue Vaubenard, 14000 Caen, FranceBorochem provides boron building blocks for chemists

Borochem

Caen, Normandy, 14000 FranceBorochem provides boron building blocks for chemists

Bertin Pharma

Parc d’activités du Pas du Lac 10 bis avenue Ampère Montigny le Bretonneux, 78180 FranceBertin Pharma, a subsidiary of Bertin Technologies, offers preclinical/clinical, pharmaceutical development, biosafety, and biomarker assay tools and services.

Bertin Pharma

Parc d'Activité du Pas du Lac 10 bis avenue Ampère Les Yvelines, 78180 Montigny-le-Bretonneux FranceBertin Pharma, a subsidiary of Bertin Technologies, offers preclinical/clinical, pharmaceutical development, biosafety, and biomarker assay tools and services.

BIOPHYDERM

Parc 2000 244, rue Claude François - Les Fauvettes 34080 MontpellierSince 1993, Biophyderm has been developing a high level of know-how in the domain of dermocosmetic assessments. Run by a dermatologist specialized in industrial dermocosmetologic developments, Biophyderm's strength lies in its staff. Biophyderm is a multidisciplinary and well-skilled team which has been working for years in a strong collaboration with its partners. In 2005, the firm incorporated Biophymed, a company specialized in developing innovative devices. Biophyderm now has a double proficiency in dermocosmetic assessments and development of scientific devices. Our speciality: biometrology, dermocosmetic assessment and biotechnological innovation.

BIOPHYDERM

244 Rue Claude François Montpellier, Occitanie, 34080 FranceSince 1993, Biophyderm has been developing a high level of know-how in the domain of dermocosmetic assessments. Run by a dermatologist specialized in industrial dermocosmetologic developments, Biophyderm's strength lies in its staff. Biophyderm is a multidisciplinary and well-skilled team which has been working for years in a strong collaboration with its partners. In 2005, the firm incorporated Biophymed, a company specialized in developing innovative devices. Biophyderm now has a double proficiency in dermocosmetic assessments and development of scientific devices. Our speciality: biometrology, dermocosmetic assessment and biotechnological innovation.

Bioxtal

227 Route de la Chapelle 227 Route de la Chapelle Saint-Félix, Auvergne-Rhône-Alpes, 74540 FranceBioxtal is a biotech company providing services to Pharmaceutical and biotechnology companies as well as academic research labs. Bioxtal offers molecular biology and purification services (E. coli, baculovirus/insect cells, mammalian). We produce batches of recombinant proteins (with or without fusion tags, labelled protein for NMR, crystallography or imaging) for HTS or other applications. Biochemistry and biophysical services include: domain boundaries and solubility screening (Split GFP systems), activity assays development, protein interactions characterization (Protein/protein, Protein/ligand, Lead compounds screening) by TR-FRET, Isothermal Titration Calorimetry, Microscale thermophoresis, Biolayer Interferometry or Thermal shift assay. We also offer protein structure determination by X-ray crystallography (protein, protein complexes, protein/antibody complexes; protein ligand complexes; structure based drug design).

BIOACTIF Eurl

2 rue George SAND OBERHAUSBERGEN, 67205 France

Biovays

Marseille, FranceBiovays offers biomarkers, molecular biology, cellular services, fluorescence services, imaging, and genetics.

Biocytex

140 Chemin de l'Armée d'Afrique Marseille, 13010 FranceBioCytex provides services to pharma and biotech companies worldwide. BioCytex develop, validate, manufacture fit-for-purpose cell-based assays. BioCytex is using cell culture and immunological tools including : Flow cytometry, ELISA, Luminescence, Cytotoxicity assays, Consulting. BioCytex perform PoC, feasibility and validation studies, and offers PK/PD services.

bioMérieux [Duplicate]

5, Rue des Aqueducs BP10 Marcy-L´Etoile, 69280 FranceSafety of cosmetics and personal care products has been a focus of bioMérieux for over 50 years. We are a leading provider of rapid and traditional microbiological solutions that help ensure consumers receive products free of microbial contamination. Our cosmetics testing portfolio includes CHEMUNEX® rapid microbiology solutions for microbial detection and enumeration. The fully-automated D-Count and BactiFlow ALS are powerful enough to detect a single bacterium, yeast or mold and allow you to shorten your production cycle by releasing your products in as little as 24 hours.

Bioluz

ZI Jalday 64500 Saint-Jean-de-Luz FranceBioluz manufactures aseptic fill/finish capacity for IV drugs in flexible bags.

Biosiris

Moulin St Genies Belfort du Quercy, 46230 FranceBiosiris offers protein sequence analysis, protein interaction site prediction, B epitope prediction, and 3D structure determination from peptide sequences.

Battelle

12 Avenue des Morgines CH-1213 Petit-Lancy Geneva, SwitzerlandBattelle is a GLP-compliant, IND and BLA-enabling CRO. We provide services that can help move projects from in vitro to in vivo through clinical support. Specifically, our core capabilities are focused around our long-standing experience and expertise in cell-based and biochemical assay development, validation and analytical and bioanalytical sample screening, proteomics, compound synthesis, HTP next generation sequencing, in vivo efficacy, safety pharmacology, toxicology, inhalation toxicology (small and large species), ADME/PK, analytical chemistry, pathology. Battelle also has deep experience developing and manufacturing medical devices, and in conjunction with customer test articles is able to validate both the device and test article together.

BioMeca

60 F ave Rockefeller BIOPARC, BIOSERRA 2 (5th floor) LYON, 69008 FranceBioMeca is a biotech service provider, expert in skin biology and biomechanics. Analytical methods using Atomic Force Microscopy and high-resolution imaging. All-inclusive services in cellular biology, skin biology, physics, 3D modelisation of biological systems: - Development of new imaging approaches and biophysics characterization - Expertise in cellular and molecular biology, skin biology, immunology - Statistics analyses and 3D reconstruction - 3D modelisation of biological systems

BioMeca

60 LYON, 69008 FranceBioMeca is a biotech service provider, expert in skin biology and biomechanics. Analytical methods using Atomic Force Microscopy and high-resolution imaging. All-inclusive services in cellular biology, skin biology, physics, 3D modelisation of biological systems: - Development of new imaging approaches and biophysics characterization - Expertise in cellular and molecular biology, skin biology, immunology - Statistics analyses and 3D reconstruction - 3D modelisation of biological systems

BioMeca

60 F ave Rockefeller BIOPARC - BIOSERRA 2 LYON, 69004 FranceBioMeca is a biotech service provider, expert in skin biology and biomechanics. Analytical methods using Atomic Force Microscopy and high-resolution imaging. All-inclusive services in cellular biology, skin biology, physics, 3D modelisation of biological systems: - Development of new imaging approaches and biophysics characterization - Expertise in cellular and molecular biology, skin biology, immunology - Statistics analyses and 3D reconstruction - 3D modelisation of biological systems

BioMeca

46 allée d'Italie LYON, 69007 FranceBioMeca is a biotech service provider, expert in skin biology and biomechanics. Analytical methods using Atomic Force Microscopy and high-resolution imaging. All-inclusive services in cellular biology, skin biology, physics, 3D modelisation of biological systems: - Development of new imaging approaches and biophysics characterization - Expertise in cellular and molecular biology, skin biology, immunology - Statistics analyses and 3D reconstruction - 3D modelisation of biological systems

Bruker Biospin [duplicate]

Wissembourg, FranceBruker Biospin offers analytical magnetic resonance instruments including NMR, preclinical MRI and EPR.

Biomérieux SA

5 rue des aqueducs Craponne, 69290 France

CAMECA

29, quai des Grésillons 92230 Gennevilliers Cedex, France

CAMECA

29 Quai des Gresillons Gennevilliers, Île-de-France, 92230 France

Chiesi farmaceutici

Immeuble le Doublon - 11 Avenue Dubonnet, 92400 Courbevoie - FranceChiesi farmaceutici offers drug development, drug discovery, and clinical trials.

CELENYS

75 Route de Lyons la Forêt Rouen, 76000 FranceCELENYS, a biotechnology company committed to the creation, development, production and commercialisation of a new generation of 3D cell culture scaffolds to bring an innovative dimension to your research! AN INNOVATIVE BIOTECHNOLOGY CELENYS is based in Rouen, France. Cofounded by Chairman and CSO, Elise Demange and Nicolas Dubois, CELENYS now comprises a competent and dynamic team of 8 individuals. CELENYS’ mission is to develop innovative scaffolds for 3D cell culture to better mimic the cell microenvironment and provide more predictive tools for drug development. In 2014 CELENYS raised 1M€ and 500 000€ in 2016 of investment from NCI Gestion and Go Capital. This funding has enabled CELENYS to develop a multidisciplinary team.

CTCPA

44 Rue d'Alésia Paris, Île-de-France, 75014 FranceThe CTCPA, center of collective research for companies which produce canned and dehydrated foods. The CTCPA achieves its general interest missions thanks to a fiscal contribution paid by French companies working in the canned and dehydrated food sector. These companies represent nearly 40% of the center’s resources. The missions include: collective research programs transfer of technology, expertise, representing the profession, scientific, technical, and regulatory watch technical support to professionals through question and answer service, valorization of the research results The research orientations of the CTCPA and the nature of its general interest missions are established through a contract of objectives and means lasting many years. This contract is defined between the minister in charge of the food sector and the concerned professional syndicate (Fiac). Each year food companies choose their desired research projects for the coming year. The result of each research project is available to any European Union industry with products in the area of competence of TFA, by simple request to the documentation center.

Centre Techniques de Champignon

22 Rue Bizard Distré, Pays de la Loire, 49400 FranceCreated in 1988, the Mushroom Technical Centre is the "arm" of the inter ANICC technique (National Interprofessional Association of Mushroom Layer). The industry players, producers and processors involved, animate and fund the CTC The CLC receives approval GEP (Good Experimental Practice) obtained in 1998 and regularly renewed since. Created in 1988, the Mushroom Technical Centre is the "arm" of the inter ANICC technique (National Interprofessional Association of Mushroom Layer). The industry players, producers and processors involved, animate and fund the CTC The CLC receives approval GEP (Good Experimental Practice) obtained in 1998 and regularly renewed since.

Cerba Research

126 Rue Emile Baudot Montpellier , 3400 FranceFor over 35 years, Cerba Research has been setting the industry standard for exemplary clinical trial conduct. Today, across five continents, with a focus on precision medicine, we are changing the paradigm of the central lab’s role in complex clinical research. From protocol inception through development and to market, our passionate experts deliver the highest quality specialized and personalized laboratory and diagnostic solutions. Cerba Research provides testing in therapeutic areas such as Cardiovascular diseases, Infectious diseases (microbiology, vaccine studies on virology and other IDs), Inflammatory disorders, Autoimmune diseases, Oncology, Metabolic diseases and Rare/Orphan diseases. Performing testing from Phase I to Phase IV studies. Cerba Research’s central lab services include routine testing, custom assay development, biobanking & storage, global project management & logistical support, operational support (including logistics, sample handling, kit building & data management) and artificial intelligence.

Cogent Communications

77 Boulevard de la République La Garenne-Colombes, Île-de-France, 92257 FranceCogent expedites the secure transfer of large data files between domestic and global locations including the U.S., U.K., Europe, Japan, China, Korea, Singapore, Australia, and Brazil. [NASDAQ: CCOI] Cogent is a Tier 1 Global Internet Service Provider with the most interconnected network in the world – connecting to 6700 networks and 1200 Data Centers in over 200 markets spanning 45 countries. Approximately 21% of the world’s Internet traffic travels our network daily. Our core product offerings include Dedicated Internet Access, Ethernet Point-to-Point, Ethernet VPLS, SDWAN, and Colocation services offered over our award-winning fiber optic, IP data-only network.

Capsugel

Zone Industrielle de Camagnon Ploërmel, Bretagne, 56800 FranceCapsugel provides, dosage form development, powder formulation, capsule gels, and filling equipment.

Centre d'Immunologie de Marseille-Luminy Imaging Immunity (ImagImm)

Parc Scientifique & Technologique de Luminy, Case 906, 13288 Marseille cedex 09, FRANCEThe Imaging Immunity – ImagImm - facility offers resources in light and fluorescence microscopy to decipher the operating mechanisms of the immune system, from molecules to whole organisms. Two engineers, Mathieu Fallet and Sébastien Mailfert manage this scientific facility under the scientific supervision of Didier Marguet. Founded in 2012 by merging the former core microscopy platform and IM2V (research and development platform). The aims of the service are to: Develop light and fluorescence microscopy methods at the state-of the-art Provide scientific and technical assistance to acquire and analyze data Train users with on-demand theoretical and practical courses Maintain instruments and ensure quality control processes Perform R&D activity for operating new biophotonic methods appropriate to the CIML scientific community ImagImm is member of the PICsL microscopy core facility (Plateforme d’Imagerie Commune du Site de Luminy) created in 2002 through a partnership between the CIML and the IBDML (Institut de Biologie du Développement de Marseille-Luminy). ImagImm is identified at the national level as “Infrastructure en Biologie Santé et Agronomie“ (IBISA) and as part of the France BioImaging network.

Centre Lago

Vonnas, Auvergne-Rhône-Alpes, 01540 FranceCentre Lago specializes in production of polyclonal antibodies in rabbits.

CreaCell

Biopolis 5, avenue du Grand Sablon 38700 La Tronche FranceCreaCell provides recombinant cell lines, cytotoxicity testing, efficacy testing, lipolysis, primary cultures, and genome integrity.

CreaCell

La Tronche, Auvergne-Rhône-Alpes, 38700 FranceCreaCell provides recombinant cell lines, cytotoxicity testing, efficacy testing, lipolysis, primary cultures, and genome integrity.

Cardiomedex

280 rue de l'Hers Escalquens, 31750 FranceCardiomedex is specialized in cardiovascular diseases and complications (heart failure with reduced or preserved ejection fraction (HFpEF), myocardial infarction, cardiac arrhythmia, cardiac hypertophy, heart failure, hypertension).

Cardiomedex

Rue Pierre et Marie Curie 516 rue Pierre et marie Curie Labège, Occitanie, 31670 FranceCardiomedex is specialized in cardiovascular diseases and complications (heart failure with reduced or preserved ejection fraction (HFpEF), myocardial infarction, cardiac arrhythmia, cardiac hypertophy, heart failure, hypertension).

Cellvax

4, rue Pierre Fontaine 91000 Evry FranceCellvax offers in vivo and in vitro disease models and imaging services.

Cellvax

Évry, Île-de-France FranceCellvax offers in vivo and in vitro disease models and imaging services.

CHEM-X-INFINITY

102 avenue Gaston Roussel Romainville, 93230 FranceCHEM-X-INFINITY provides original libraries of small organic molecules and fragments.

CHEM-X-INFINITY

102 avenue Gaston Roussel Romainville, 93230 FranceCHEM-X-INFINITY provides original libraries of small organic molecules and fragments.

CHU Grenoble Alps

38043 Grenoble CEDEX 9 Grenoble FranceThe University hospital Grenoble Alpes (CHU of Grenoble ) is a French university hospital center.

Cynbiose

Marcy l'Étoile, FranceCynbiose est une société de services unique en Europe qui a pour but le développement et la commercialisation de modèles innovants dans les espèces primates afin d’accélérer les phases précliniques du développement des candidats médicaments. Nous mettons en œuvre des études exploratoires et nous développons également des modèles de pharmacologie dans les principales aires thérapeutiques afin d’établir un lien solide entre le développement préclinique et les phases cliniques. Nous souhaitons donner un sens aux services apportés à nos clients, convaincus que la qualité de la relation ainsi que la mise en commun de nos expertises sont des leviers essentiels pour assurer la réussite d’un projet.

Cynbiose

Marcy l'Étoile FranceCynbiose est une société de services unique en Europe qui a pour but le développement et la commercialisation de modèles innovants dans les espèces primates afin d’accélérer les phases précliniques du développement des candidats médicaments. Nous mettons en œuvre des études exploratoires et nous développons également des modèles de pharmacologie dans les principales aires thérapeutiques afin d’établir un lien solide entre le développement préclinique et les phases cliniques. Nous souhaitons donner un sens aux services apportés à nos clients, convaincus que la qualité de la relation ainsi que la mise en commun de nos expertises sont des leviers essentiels pour assurer la réussite d’un projet.

CytobodX

170 traverse dy Rayol Saint Maximin la Sainte Baume, 83470 FranceCytobodX is a french biotech company based in Marseille. At CytobodX, we produce, purify and characterize soluble and membrane proteins using state-of-the-art technologies to meet the specific needs of your research. The originality of CytobodX is to be able to rapidly produce native membrane proteins by using an innovative technology. Membrane proteins are directly expressed and embedded on the surface of purified Extracellular Vesicles (EVs) and ready for downstream applications : Interaction or functional studies, structural characterization or antibody/nanobody generation. This technology allows CytobodX to guarantee optimal quality and stability of the proteins produced and marketed.

Clean Cells

Boufféré, FranceClean Cells provides full GMP services for cell bank and viral production, full GMP characterization of process and final product, development/validation of in vitro assays, ADCC assays, and storage of cell bank and products.

Clean Cells

Boufféré, Pays de la Loire, 85600 FranceClean Cells provides full GMP services for cell bank and viral production, full GMP characterization of process and final product, development/validation of in vitro assays, ADCC assays, and storage of cell bank and products.

Clean Cells

Rue Marie Curie Parc d’Activités Vendée Sud Loire 1 Montaigu-Vendée, 85600 FranceClean Cells provides full GMP services for cell bank and viral production, full GMP characterization of process and final product, development/validation of in vitro assays, ADCC assays, and storage of cell bank and products.

Charles River Laboratories

9, allée du Moulin Berger Ecully, 69130 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

1 Rue Graham Bell Zi De Brais CS 40309, Saint-Nazaire, 44605 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

RN 13 Route de Pacy, Miserey, 27930 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

2109 Route De Châtillon Domaine des Oncins Nuelles, Romans, 01400 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

2109 Route De Chatillon Chatillon-sur-Chalaronne, Oncins Nuelles, 1400 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

SAS 329 Impasse Du Domaine Rozier Saint Germain-Nuelles, Lyon, 69210 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

Les Oncins Saint Germain , Nuellles, 69210 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

329 Impasse Du Domaine Rozier Saint-Germain-Nuelles, 69210 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

329 Impasse Du Domaine Rozier Saint-Germain-Nuelles, 69210 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

1 RUE GRAHAM BELL Zi De Brais CS, Saint-Nazaire, 44605 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

Charles River Laboratories

RN 13, ROUTE de PACY Miserey, 27930 FranceCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. Recently Charles River acquired Chantest, WIL, MPI, KWS Biotest, Brains On-line, CiTox LAB, Solvo Biotechnology, Distributed Bio, Cognate Bioservices, Cobra Biologics, ViGene, and Retrogenix. To learn more about our unique portfolio and breadth of services, visit www.criver.com, www.solvo.com, www.cognatebioservices.com, www.cobrabio.com and www.retrogenix.com

CYPRIO

102, avenue Gaston Roussel Romainville, Ile de France, 93230 FranceWe propose a physiologically relevant culture model, HepatoPearl, that predicts liver in vivo response with improved precision. Easy to handle and adaptable to any bioassay, our system makes 3D Hepatocyte culture accessible to everyone. Our liver mimicking spheroids, HepatoPearls, are designed: • to address fundamental questions in biological research • as a reliable tool for drug screening assays • to become a novel solution for therapeutical and biomedical applications

CYPRIO

6 Rue Jean Calvin IPGG - 2nd floor Paris, 75005 FranceWe propose a physiologically relevant culture model, HepatoPearl, that predicts liver in vivo response with improved precision. Easy to handle and adaptable to any bioassay, our system makes 3D Hepatocyte culture accessible to everyone. Our liver mimicking spheroids, HepatoPearls, are designed: • to address fundamental questions in biological research • as a reliable tool for drug screening assays • to become a novel solution for therapeutical and biomedical applications

CYPRIO

10 Rue Vauquelin Paris, 75005 FranceWe propose a physiologically relevant culture model, HepatoPearl, that predicts liver in vivo response with improved precision. Easy to handle and adaptable to any bioassay, our system makes 3D Hepatocyte culture accessible to everyone. Our liver mimicking spheroids, HepatoPearls, are designed: • to address fundamental questions in biological research • as a reliable tool for drug screening assays • to become a novel solution for therapeutical and biomedical applications

CovalAb

11 avenue Albert Einstein 69100 Villeurbanne FranceCovalAb offers antibodies, peptide design, antibody services, synthesis, and ELISAs.

CovalAb

11 Avenue Albert Einstein Villeurbanne, 69100 FranceCovalAb offers antibodies, peptide design, antibody services, synthesis, and ELISAs.

ClinSearch

110 Avenue Pierre Brossolette Malakoff, 92240 FranceClinSearch is a European Health Research Organizationwhich provides Consultancy and Operational services for Medical Device and Drug Development. We offer more than quality at each step of your project, more than a highly qualified team, more than customer satisfaction… ClinSearch is committed to offer cost-effective solutions for designing and managing clinical evaluations, real-life studies or any other healthcare assessment. This is why ClinSearch is known as a company committed to results and has earned a reputation for delivering practical, measurable and high added-value data.

Calixar

Bâtiment Laennec 60 avenue ROCKEFELLER LYON , 69008 FranceCalixar develops new approaches to isolate in solution - with the highest purity levels - full-length membrane antigens and proteins (GPCRs, Ion Channels, Transporters, Receptors and Viral Proteins), while keeping their structural and functional integrity. Calixar’s approach represents an opportunity for pharmaceutical companies to start and work with high quality targets or antigens before formulating vaccines, developing antibodies, and/or discovering a primary lead through Structure Based Drug Design or High Throughput Screening assays. CALIXAR's team is trained to perform ligand binding assays using the MicroScale Thermophoresis (MST) combined with Isothermal Spectral Shift detection. This cutting-edge technology offers to scientists and researchers the possibility to obtain accurate ligand binding parameters and compare several ligands in terms of binding properties. Thanks to the Monolith X (Nanotemper) device, CALIXAR enhances its analytical capabilities for characterizing protein-ligand interactions adapted to a wide range of membrane targets (GPCRs, ion channels, transporters, enzymes, …).

CILcare

Incubateur de l’Institut de la Vision (Voir et Entendre), 74 rue du Faubourg Saint Antoine, 75012 Paris – FranceCILcare is an R&D services company dedicated to hearing deficiencies. CILcare supports biotechs, medtechs and pharmas from all over the world in their preclinical and clinical development in hearing loss and tinnitus. CILcare has developed a unique lab platform gathering acoustic, electrophysiology, behavioral, histology and imaging technologies to perform preclinical efficacy studies on different models of hearing loss and tinnitus in rodents as well as pharmacokinetics studies to assess the exposure of the candidates in the inner ear and other targeted organs. The three founders began working on issues related to the aging population at pharma giant Sanofi – in complementary disciplines. They realized there was a niche but growing market servicing research into hearing deficiencies and founded CILcare in 2014. Today, the 9-person team is considered the worldwide leader of services in hearing research and development.

CILcare

2196 Boulevard de la Lironde Parc Scientific Agropolis II Batiment 2 34980 Montferrier sur Lez FranceCILcare is an R&D services company dedicated to hearing deficiencies. CILcare supports biotechs, medtechs and pharmas from all over the world in their preclinical and clinical development in hearing loss and tinnitus. CILcare has developed a unique lab platform gathering acoustic, electrophysiology, behavioral, histology and imaging technologies to perform preclinical efficacy studies on different models of hearing loss and tinnitus in rodents as well as pharmacokinetics studies to assess the exposure of the candidates in the inner ear and other targeted organs. The three founders began working on issues related to the aging population at pharma giant Sanofi – in complementary disciplines. They realized there was a niche but growing market servicing research into hearing deficiencies and founded CILcare in 2014. Today, the 9-person team is considered the worldwide leader of services in hearing research and development.

CILcare

Rond-Point B. Franklin - Cap Omega, CS39521 France Montpellier, Choisir, 34960 FranceCILcare is an R&D services company dedicated to hearing deficiencies. CILcare supports biotechs, medtechs and pharmas from all over the world in their preclinical and clinical development in hearing loss and tinnitus. CILcare has developed a unique lab platform gathering acoustic, electrophysiology, behavioral, histology and imaging technologies to perform preclinical efficacy studies on different models of hearing loss and tinnitus in rodents as well as pharmacokinetics studies to assess the exposure of the candidates in the inner ear and other targeted organs. The three founders began working on issues related to the aging population at pharma giant Sanofi – in complementary disciplines. They realized there was a niche but growing market servicing research into hearing deficiencies and founded CILcare in 2014. Today, the 9-person team is considered the worldwide leader of services in hearing research and development.

CILcare

378 rue du Professeur Blayac Montpellier, Occitanie, 34080 FranceCILcare is an R&D services company dedicated to hearing deficiencies. CILcare supports biotechs, medtechs and pharmas from all over the world in their preclinical and clinical development in hearing loss and tinnitus. CILcare has developed a unique lab platform gathering acoustic, electrophysiology, behavioral, histology and imaging technologies to perform preclinical efficacy studies on different models of hearing loss and tinnitus in rodents as well as pharmacokinetics studies to assess the exposure of the candidates in the inner ear and other targeted organs. The three founders began working on issues related to the aging population at pharma giant Sanofi – in complementary disciplines. They realized there was a niche but growing market servicing research into hearing deficiencies and founded CILcare in 2014. Today, the 9-person team is considered the worldwide leader of services in hearing research and development.

CILcare

378 rue du Professeur Blayac Montpellier, county (optional), 34080 FranceCILcare is an R&D services company dedicated to hearing deficiencies. CILcare supports biotechs, medtechs and pharmas from all over the world in their preclinical and clinical development in hearing loss and tinnitus. CILcare has developed a unique lab platform gathering acoustic, electrophysiology, behavioral, histology and imaging technologies to perform preclinical efficacy studies on different models of hearing loss and tinnitus in rodents as well as pharmacokinetics studies to assess the exposure of the candidates in the inner ear and other targeted organs. The three founders began working on issues related to the aging population at pharma giant Sanofi – in complementary disciplines. They realized there was a niche but growing market servicing research into hearing deficiencies and founded CILcare in 2014. Today, the 9-person team is considered the worldwide leader of services in hearing research and development.

CDM Lavoisier

7 rue Labie 75017 Paris FranceCDM Lavoisier specializes in the production of pharmaceutical drugs and medical devices.

CDM Lavoisier

Paris, Île-de-France FranceCDM Lavoisier specializes in the production of pharmaceutical drugs and medical devices.

Creapharm-MP5

10 Rue des Boules 63200 Riom, FranceCreapharm-MP5 offers cytotoxics, high potency products, protein, antibody, and manufacturing services.

Chelatec

Route de Saint-Herblain Nantes, Pays de la Loire, 44100 FranceChelatec offers radioactive labeling, in vivo imaging and pharmacokinetics, and in vitro testing services.

College of France Center for Interdisciplinary Research in Biology (CIRB)

Cnrs/ Umr 7241 - Inserm U1050 11, Place Marcelin Berthelot Paris Cedex 05, 75231 FranceThe Center for Interdisciplinary Research in Biology (CIRB) is a novel Collège de France / CNRS / INSERM research structure located at the Collège de France in the Center of Paris. Nine teams from different horizons have recently founded this structure with the spirit to foster new collaborations within biological domains and across the usual disciplinary divide. In the long term the nine founding groups, specialized in the fields of infectious diseases, neurosciences and cardio-vascular research, will be rejoined by a similar number of new groups, primarily junior groups, including chemists, physicists and mathematicians with a strong interest for biological sciences. The new Center will benefit from being in the vicinity of several other laboratories and from an extraordinary rich intellectual milieu, with conferences that cover all aspects of knowledge. Outside of Collège de France, CIRB has developed strong interactions with high profile neighboring institutions, in particular the Ecole Normale Supérieure and the Curie Institute.

CEPiA

Paris, Île-de-France FranceCEPiA specializes in the manufacturing of opiates/opioids, coricosteroids, hormones, biotech, fermentation, prostaglandins and synthesis products.

CERB

Baugy, FranceCERB (Centre de Recherches Biologiques) offers in vivo and in vitro toxicology studies, pharmacological disease models, and bioanalytical services.

Cypath-rb

201 Route de Genas VILLEURBANNE, 69100 FranceLed by a pathologist with more than 15 years of experience in academic and industrial research, CYPATH-RB is a company dedicated to research and development in pathology. Part of the CYPATH Group, which analyzes more than 700,000 samples per year, CYPATH-RB provides researchers, pharmaceutical groups or CROs with human biological samples analyzed as part of the treatment. CYPATH-RB thus provides digitized slides (HE and / or HES) as well as biological samples (FFPE, +/- fresh tissue) annotated on the histopathological, molecular +/- clinical level. CYPATH-RB also offers technical and medical services on murine models, whether in tumor pathology or in toxicopathology (ERT label). Finally, CYPATH-RB has specialized in the co-development and clinical validation of artificial intelligence tools in pathology, wishing to become a major player in digital pathology and clinical research in France. The 100% digital turn for all routine diagnostics of the CYPATH group is part of this desire. Contact: cypath-rb@cypath.fr

CliniSciences

74 Rue Des Suisses Nanterre, 92000 FranceCliniSciences is a French company headquartered in Paris. CliniSciences is a distributor products & services from suppliers based all around the world. CliniSciences owns 10 other companies (Anawa, Biotrend, Generon, Hexabiogen, Kyvobio, Quimigen) based throughout Europe including the United Kingdom, Germany, Spain, Italy, The Netherlands & Switzerland. Through these companies we offer life science reagents, services and instruments. We sell products & services for research and diagnostic use. Products include reagents, cells, human samples and more. Services include antibody development, peptide synthesis, bulk manufacture, humanization and more.

CliniSciences

74 rue des Suisses Nanterre, France, 92000 FranceCliniSciences is a French company headquartered in Paris. CliniSciences is a distributor products & services from suppliers based all around the world. CliniSciences owns 10 other companies (Anawa, Biotrend, Generon, Hexabiogen, Kyvobio, Quimigen) based throughout Europe including the United Kingdom, Germany, Spain, Italy, The Netherlands & Switzerland. Through these companies we offer life science reagents, services and instruments. We sell products & services for research and diagnostic use. Products include reagents, cells, human samples and more. Services include antibody development, peptide synthesis, bulk manufacture, humanization and more.

CEBIPHAR

1, rue de la Bodinière Fondettes, 37230 FranceCebiphar, French CRO member of TERANGA Group (150 employees), offers its expertise to the veterinary pharmaceutical, chemical and cosmetics industry. This expertise encompasses 4 strategic activities: Development and control Stability studies Veterinary preclinical and clinical studies Technical and regulatory affairs Member of TERANGA Group, Cebiphar offers relevant synergies with its sister companies : ACM Pharma with regards to microbiological services UPS Consultants with regards to training sessions. Cebiphar is a team of 70 employees with 40years experience, 1800 products being studied, 800 veterinary preclinical & clinical studies. More than 150 clients work with us on a regular basis, in France and internationally: start-up, big pharma, generic companies, CMOs (API & DP)s, Cebiphar’s sustained commitment to quality enables the performance of studies according to GMP, GLP and GCP quality standards. Cebiphar benefits from the Research Credit Tax certification.

CEBIPHAR

3 Rue des Satellites 3 Rue des Satellites Toulouse, Occitanie, 31400 FranceCebiphar, French CRO member of TERANGA Group (150 employees), offers its expertise to the veterinary pharmaceutical, chemical and cosmetics industry. This expertise encompasses 4 strategic activities: Development and control Stability studies Veterinary preclinical and clinical studies Technical and regulatory affairs Member of TERANGA Group, Cebiphar offers relevant synergies with its sister companies : ACM Pharma with regards to microbiological services UPS Consultants with regards to training sessions. Cebiphar is a team of 70 employees with 40years experience, 1800 products being studied, 800 veterinary preclinical & clinical studies. More than 150 clients work with us on a regular basis, in France and internationally: start-up, big pharma, generic companies, CMOs (API & DP)s, Cebiphar’s sustained commitment to quality enables the performance of studies according to GMP, GLP and GCP quality standards. Cebiphar benefits from the Research Credit Tax certification.

CTIBiotech

Batiment A16, 5 avenue Lionel TERRAY MEYZIEU, Rhone, 69330 FranceCTIBiotech develops and produces predictive models of human cells and tissues for biomedical, pharmaceutical and dermato-cosmetic research and development. CTIBiotech is home to a team of world-renowned experts who have innovated in the fields of bioengineering and regenerative medicine over the past 30 years. CTIBiotech works in partnership with public and private organizations to develop innovative solutions for efficacy and safety testing of active ingredients, dermatocosmetic products, therapeutic candidates, cell therapies and medical devices. CTIBiotech is organized around three divisions. CTIBiosourcing®: a large human cells and tissue biobank with dedicated human biological samples procurement team, manufacturing of biological models, cells and human tissues. More than 50,000 tissue samples in stock or on demand for biological supply from a network of 200 healthcare partners around the world. Please check our catalogue of cells and tissue products and current biobank inventory: http://ctibiotech.com/news/Official_CTIBiotech_PriceList_NOPRICE_2022.pdf http://ctibiotech.com/news/CTIBioBank_Inventory_TL20210301v1.xlsx Further to this, CTIPharma™ open innovation (model development) and services (contract testing) activities to support drug development, biologics, medical device in oncology, immuno-oncology & regenerative medicine. CTISkin™ open innovation (model development) and services (contract testing) activities to support your skin biology safety & efficacy evaluation projects. Our human tissue models are of three types; Ex Vivo: skin biopsy, scalp biopsy, baby skin model, sebaceous gland model etc Blood samples, bone marrow samples, tumour and cancer biopsies (lung, prostate, pancreas, liver, breast, ovary, head & neck, colorectal, haematological malignancies, etc). In Vitro: with a qualified and accredited Biobank of several thousand cell samples from donors of different ages, genders, phototypes Keratinocytes, Fibroblasts, Sebocytes, Melanocytes, Dermopapilla, Immune cells etc A range of cancer cell types and cancer associated fibroblasts. 3D Bioprinted human Skin: Our 3D bioprinted skins have a defined structure with a functional basement membrane separating a dermis (containing fibroblasts) from the epidermis (containing keratinocytes at different levels of maturation/cornification). These models are derived from single human donors and can be supplemented with other cell types depending on the model required for the efficacy claim being made. For example, the immune system (involved in inflammation or allergies), melanocytes (involved in pigmentation) or sebocytes (involved in acne, oily skin, dry skin). Research into the involvement of the M1 and M2 immune pathways in the different stages of inflammation has led us to produce models suitable for screening the safety and efficacy of ingredients, formulated or finished products, cosmetic or medical devices. CTIBioTumor cancer research bioassays accurately reproduce, in vitro, the interactions between human cancer cells and all other types of cells that form the tumor microenvironment. Delivery of standardised skin models to your laboratories: => CTISkin™Ex vivo kit. This new product is a standardised and ready-to-use solution for your efficacy and safety tests. Collected immediately after surgery, we provide you with the freshest possible skin biopsies that can be used for up to 11 days. Suitable for all ex vivo skin bioassays including: ✔ Anti-pollution test ✔ Hydration test ✔ Revitalisation test ✔ Healing test ✔ Sun protection test ✔ Anti-inflammatory test ✔ etc Also => CTISkin™ dermatomed frozen skin Dermatomed skin samples frozen after surgery and delivered to your laboratory And also => CTISkin™ Single Donor Kit Provides access to primary human cells from a single donor to support your ethical and regulatory compliant in vitro bioassays. Included in the kit are: ✔ From 2 to 6 primary cell types (keratinocytes, fibroblasts, adipocytes, sebocytes, melanocytes, blood cells) from the same donor. ✔ Cell culture media defined for each cell type: CTISKIN reagent. ✔ Certificate of analysis ✔ Recommended protocol ✔ Data sheet

CNRS-UMR 8000 - The Laboratory of Physical Chemistry

15 Rue Georges Clemenceau Orsay, Île-de-France, 91400 FranceLe Laboratoire de Chimie Physique (LCP) est une unité mixte de recherche (UMR 8000) de l’Université Paris-Sud et du CNRS, localisée sur le campus de la faculté des Sciences d’Orsay.

CovalX

Technopole Montesquieu 2, Allée Ulysse Gayon MARTILLAC, 33650 FranceCovalX offers mass spectrometry service for protein characterization with special focus on conformational epitope mapping (HDX-MS, XL-MS). Other services includes sequence verification, intact mass, protein interaction test, aggregation. all mass spectrometry analysis for therapeutic proteins.

CovalX

146, rue Leo Saignat Bordeaux, Cedex, 33076 FranceCovalX offers mass spectrometry service for protein characterization with special focus on conformational epitope mapping (HDX-MS, XL-MS). Other services includes sequence verification, intact mass, protein interaction test, aggregation. all mass spectrometry analysis for therapeutic proteins.

CHEMSTEP

11 Rue Jacques Latrille Site Montesquieu Martillac, 33 650 FranceCHEMSTEP carries out contract research and developement in all areas of organic, medicinal chemistry and biotechnology.

Centre Francais du Riz

Mas du Sonnailler n°80 VC 108 de Gimeaux 13200 ARLESThe French Rice Center's mission is to provide rice farmers how to produce quality rice at competitive prices, as part of a harmonious relationship with the environment. Taking the usual missions a technical center, the Rice French Centre is experimenting with cultivation techniques, implements a variety selection program also provides ongoing technical support to rice farmers. This site aims to present our technical center, research topics, publications and to report the results of our experiments. You will also find an image bank, illustrating the land of Camargue rice and a directory of the sector. Enjoy!

CapEval Pharma

218, avenue Marie Curie Archamps Technopole Archamps, 74160 FranceCapEval Pharma provides pharmaceutical consultancy services from early pre-clinical to clinical development, specifically in the sectors of Safety, Toxicology, Pharmacology, Ophthalmology, ADME/PK, analytical development, QA, CMC-Regulatory Affairs and Compliance. In addition, CapEval provides expert assessment for due diligence, veterinary drugs, cosmetics, agrochemicals and chemicals as well as staff training.

CYTOO

7 parvis Louis Néel, CS 20050 Minatec - BHT - Bât. 52 38040 Grenoble cedex 9 FranceCYTOO is a biotech company developing physiologically relevant cell-based assays compatible with High Content Screening (HCS) by restoring physical cues to cell culture. The company has developed MyoScreenФ™, the first human skeletal muscle in vitro model compatible with HCS. As part of CYTOO’s engagement into drug discovery, several assays linked to muscle metabolism, contractility, and disorders (Duchenne Muscular Dystrophy, sarcopenia, cachexia) have been developed and are being screened to identify novel active compounds. CYTOO has also developed EpiScreen™, a stratified skin microepidermis model, enabling high content analysis and high throughput screening for applications in cosmetology and dermatology.

Cetim Grand Est

21 Rue de Chemnitz Mulhouse, Grand Est, 68200 France1) Multi-material expertise on Metals, Polymers, composites, Glass - Failures and investigations in laboratory and on-site. - Ruptures, cracks, corrosion, various degradations,… - Surface treatments and coatings - Defect searching - Chemical and physicochemical analysis - VOC analysis, pollution, foreign parts,… - Mechanical characterisation (parts and systems) 2) Engineering of materials (Polymers, Ceramics, Recycled composites) - Formulation - Compounding - Pilot production 3) Multiphysics engineering and sustainability - Multiphysic engineering … - Cycled pressure tests - Pressure-Vibration-Temperature tests - Testing under electrical environment - Testing under combined solicitations - Vibration tests - Climatic tests and thermal shocks - Salt spray, UV and fluid resistance tests - Standard and custom testing

cellenion SASU

60 Avenue Rockefeller Bâtiment BioSerra 2 Lyon, 69008 FranceCellenion is a company offering solutions and technologies for controlled cell dispensing with applications in the field of single-cell isolation and spheroid and oirganoïd sorting. Cellenion has developed cellenONE®, a revolutionary platform for automated single cell isolation and dispensing. Gentle piezo-acoustic technology, combined with an optical setup for automated image based selection, cellenONE allows high throughput manipulation of single cell while providing outstanding precision unlike any other dispensing and microfluidic platforms. These features make it an ideal platform for both cloning applications and sample preparation prior to single cell analyses. By precisely dispensing single cells and reagents in picoliter droplets, cellenONE® is compatible with a range of substrates from microplates (384, 1536wp) to microwells substrates. The later allow drastic reduction in reaction volumes and subsequently costs per single-cell analysis. Additionally, ability to work with minute volume and cell numbers makes cellenONE a unique platform for single cell isolation from small biopsies or other rare cell samples. Indeed, recent collaborative work with leading researchers has demonstrated unseen cell recovery (> 95%) from minute patient samples (< 5µL) containing fewer than 100 cells. This platform is now allowing researchers and clinicians alike new insights in samples that were previously not analysable using other single cell analytical techniques. Recently, Fluorescent Image Based Single Cell Isolation technology (FIBSCITM ) was launched. It now allows the use of fluorescent markers to select only single cell of interest. Initial investigations have demonstrated its benefit for excluding dead cells and also enrichment of cancer cells of interest from mixed cell population for both cloning and single cell sequencing applications.

cellenion SASU

60 Avenue Rockefeller Lyon, Auvergne-Rhône-Alpes, 69008 FranceCellenion is a company offering solutions and technologies for controlled cell dispensing with applications in the field of single-cell isolation and spheroid and oirganoïd sorting. Cellenion has developed cellenONE®, a revolutionary platform for automated single cell isolation and dispensing. Gentle piezo-acoustic technology, combined with an optical setup for automated image based selection, cellenONE allows high throughput manipulation of single cell while providing outstanding precision unlike any other dispensing and microfluidic platforms. These features make it an ideal platform for both cloning applications and sample preparation prior to single cell analyses. By precisely dispensing single cells and reagents in picoliter droplets, cellenONE® is compatible with a range of substrates from microplates (384, 1536wp) to microwells substrates. The later allow drastic reduction in reaction volumes and subsequently costs per single-cell analysis. Additionally, ability to work with minute volume and cell numbers makes cellenONE a unique platform for single cell isolation from small biopsies or other rare cell samples. Indeed, recent collaborative work with leading researchers has demonstrated unseen cell recovery (> 95%) from minute patient samples (< 5µL) containing fewer than 100 cells. This platform is now allowing researchers and clinicians alike new insights in samples that were previously not analysable using other single cell analytical techniques. Recently, Fluorescent Image Based Single Cell Isolation technology (FIBSCITM ) was launched. It now allows the use of fluorescent markers to select only single cell of interest. Initial investigations have demonstrated its benefit for excluding dead cells and also enrichment of cancer cells of interest from mixed cell population for both cloning and single cell sequencing applications.

Cenexi

Fontenay-sous-bois, FranceCenexi offers contract manufacturing for tablets,hard gelatine capsules,ampoules,syrups,packaging and suppositories.

Cenexi

Fontenay-sous-Bois, Île-de-France, 94120 FranceCenexi offers contract manufacturing for tablets,hard gelatine capsules,ampoules,syrups,packaging and suppositories.

ClinReal Online

7 avenue Marcel Langer 31400 TOULOUSE, FRANCEClinReal Online is a company specialized in the field of Observational Consumer Tests in real conditions of use in Beauty Care. ClinReal Online, a limited liability company with the authorized capital of 40.000 euros, was created in 2005 and constitutes the result of over twenty years of research devoted to the methods and techniques in clinical research and provision of services. ClinReal Online collaborates with the industrialist and his teams of research and marketing throughout the process of development of the produced dermo-cosmetic and other products of care: methodological and organisational advice, monitoring, data management, biostatistics, exploitation and development of the results, administrative management of the relations between investigators and promoters, scientific papers, …

Cell&Co Biorepository

ZAC de Champ Lamet Rue de Chambussière Pont du Château, 63430 FranceCell&Co Biorepository offers a flexible, high-quality, secure, traceable and complete solution for any organization confronted with a problem related to the management or storage of biological or clinical samples.

Cerom

155, rue du Faubourg Saint-Denis Paris, 75010 FranceCerom provides cardiovascular analytical service.

Creapharm

ZA Air Space Avenue Magudas Le Haillan, 33185 FranceCreapharm offers clinical supply production, packaging, distribution, and logistic services.

Creapharm

Le Haillan, Aquitaine-Limousin-Poitou-Charentes, 33185 FranceCreapharm offers clinical supply production, packaging, distribution, and logistic services.

Cohiro

7 Boulevard Jeanne d’Arc DIJON CEDEX 21079 BP 87900 FranceCOHIRO offers fee-for-services research and development activities to companies involved in the production of pharmaceutical products and dietary complements and to the chemical industry. COHIRO is a spin-off of the LPPCM (Laboratory of Cardio-Metabolic Pharmacology and Physiopathology) located in Faculty of Medicine and Pharmacy of the University of Burgundy in Dijon (France).

Carpaccio.cloud

28 Quai Pierre Scize Lyon, 69009 FranceCARPACCIO.cloud operates in the Digital Pathology space offering a custom, high throughput quantitative and qualitative histological image-analysis service with unsurpassed quality and speed. Currently focusing on muscle cross-sections and biopsies, we measure key parameters, presented in an easy to read report to assist the pathologist in formulating a diagnostic or the researcher in appreciating the physiological state of the tissue. Our solution is distributed as a full-service and will soon be available via internet anywhere in the world!

Carpaccio.cloud

28 Quai Pierre Scize Lyon / Auvergne Rhône-Alpes, Rhône, 69009 FranceCARPACCIO.cloud operates in the Digital Pathology space offering a custom, high throughput quantitative and qualitative histological image-analysis service with unsurpassed quality and speed. Currently focusing on muscle cross-sections and biopsies, we measure key parameters, presented in an easy to read report to assist the pathologist in formulating a diagnostic or the researcher in appreciating the physiological state of the tissue. Our solution is distributed as a full-service and will soon be available via internet anywhere in the world!

CellMade

Impasse des Sources Ruffieux, Auvergne-Rhône-Alpes, 73310 FranceCellMade is a biopharmaceutical company focused on the development and commercialization of early diagnostic and prognostic tests and novel therapeutics to prevent development of Metabolic Disease and related co-morbidities. The ever-increasing prevalence of Obesity affects millions of people worldwide. The Metabolic Syndrome and its hepatic manifestation, NAFLD-NASH is a key pathological condition triggered by the noxious biochemical pathways of Obesity. Despite the high unmet medical needs, there are currently no approved drugs for treating NAFLD-NASH. The current main recommendation is lifestyle modification, which is only partially effective. The scientific evidence on the looming pandemic of Obesity is now overwhelming. It is thought that the spreading of the disease is mediated via circulating inflammatory messengers. As in any degenerative disease, early diagnosis is the key to avoid harmful, and even deadly, effects. There is high demand for a non-invasive, high-accuracy diagnostic and prognostic approach. CellMade identified and validated a set of blood lipids that allow for discrimination between the various stages of NAFLD-NASH enabling to predict patient's risk profile and reactivity to treatment schedules. The successful validation of the biomarker signatures represents a cornerstone advancement to address the societal challenges related to the Obesity pandemic and the development of associated comorbidities such as T2DM, CVD and COPD. Early diagnosis will overcome the costs issues affecting the current clinical scenario, as the disease development is still reversible and could be addressed therapeutically. We at CellMade believe in Open Innovation and therefore established a dedicated range of laboratory services, derived from our own research activities, that can help scientists in further developing tools for Metabolic Disease. Our multidisciplinary team has developed an innovative systems biology approach enabling high-content and robust analysis of cell models required for a diverse range of applications such as efficacy and safety testing of new drug compounds or the discovery of biomarkers. CellMade provides a comprehensive catalog of Services: Biobanking, Cell-based assays, Cytometry and Mass Spectrometry assays and Bioinformatics for annotation of obtained data and construction of data-bases.

Drugdesigntech SA

Chemin des Aulx, 16 Plan-les-Ouates, Geneva, 1228 Switzerland

Diverchim

6 rue du Noyer Roissy-en-France, Roissy CDG, 95 734 FranceFounded in 2000, DIVERCHIM is the leading French company for organic synthesis of original molecules bringing its customers a top level expertise. DIVERCHIM is a Contract Research Organisation (CRO) in organic chemistry. Our teams combine experience in drug discovery and process development, medicinal chemistry, parallel synthesis, biochemical tools and fine chemicals to deliver you with unique chemistry solutions to achieve your requirements. Diverchim specifies in complex multi-steps synthesis, low temperature chemistry, asymmetric, organometallic, cyclopropane, pyrrolidine, oxetane chemistry... Besides Diverchim can scale-up existing processes or develop a new process for existing products. Our Custom Synthesis capabilities range from mg to cGMP kilogram scale. DIVERCHIM offers reference products for screening and building blocks for discovery (catalog).

Dendritics

Lyon, FranceDendritics provides dendritic cell antibodies and dendritic cell related services.

Dendritics

BP61 - 27 chemin des peupliers- 69572 Dardilly FranceDendritics provides dendritic cell antibodies and dendritic cell related services.

Dendritics

Lyon, Auvergne-Rhône-Alpes FranceDendritics provides dendritic cell antibodies and dendritic cell related services.

DIVA Expertise

1 Place Pierre Potier Toulouse, Occitanie, 31100 FranceDIVA Expertise is a French preclinical CRO specialized in applied research on Human adipose tissue. We assess the efficiency of test items on our in vitro and ex vivo models we developed from Human adipose tissue. The aim is to bring either the first proof-of-concepts OR the preclinical proof of efficiency of your items. To achieve these goals, DIVA Expertise has set-up state-of-the-art technologies in cell and molecular biology, imaging and biochemistry; as well as an established and functional network with renowned facilities and clinical partners. DIVA Expertise assists you in the optimization of your R&D projects, the identification of novel targets and shorten the time to market of your final products.

DIVA Expertise

1 Place Pierre Potier Toulouse, Occitanie, 31100 FranceDIVA Expertise is a French preclinical CRO specialized in applied research on Human adipose tissue. We assess the efficiency of test items on our in vitro and ex vivo models we developed from Human adipose tissue. The aim is to bring either the first proof-of-concepts OR the preclinical proof of efficiency of your items. To achieve these goals, DIVA Expertise has set-up state-of-the-art technologies in cell and molecular biology, imaging and biochemistry; as well as an established and functional network with renowned facilities and clinical partners. DIVA Expertise assists you in the optimization of your R&D projects, the identification of novel targets and shorten the time to market of your final products.

Danone

15, rue du Helder Paris, 75 439 FranceDanone focuses on research in nutrition, microbiology, immunology, and neuroscience.

Domain Therapeutics

BIOPARC 850 Boulevard Sébastien Brant 67400 ILLKIRCH-STRASBOURG FranceDomain Therapeutics NA (DTNA) Inc. specializes in G Protein-Coupled Receptor (GPCR) and Receptor Tyrosine Kinase (RTK) signaling and function. Our BRET-based bioSensAllTM biosensor technology allows for detailed and broad-spectrum signaling profiling of GPCRs, RTKs and their ligands, while leaving these receptors untagged. This technology revolves primarily around the real-time monitoring of receptor proximal events immediately linked to the transmembrane receptor activity, namely heterotrimeric G protein activation and β-arrestin coupling for the GPCRs, and SH2-domain proteins for the RTKs. The GPCR assay brings the unique capacity to quantify the engagement of 14 distinct heterotrimeric G protein subtypes as well as both non-visual β-arrestin isoforms. The RTK assay gives the possibility to follow the recruitment of various SH2-domain proteins and study the complete trafficking of these receptors. Both assays provide a complete and detailed fingerprint of any GPCR / RTK ligand and allow to study the impact of receptor mutations on their signaling. This data is particularly valuable in a screen / early drug development program to select and optimally design your lead compound. Domain Therapeutics applies a multi-string corporate strategy to grow its business through: validation of its technologies through collaborative partnerships with Pharma/Biotechs, generation of an internal pipeline of 1st in class drug candidates for high unmet needs in CNS and oncology, valuation of its preclinical assets through spin-out vehicles, financed by leading investment funds or supported by development-only companies.

Delpharm

6-8 rue du 4 septembre Batiment B - Le Poversy 92130 Issy Les MoulineauxDelpharm provides development and production of pharmaceutical products.

Drugabilis

5 rue Jean-Baptiste Clément Châtenay-Malabry, 92290 FranceDrugabilis offer includes solubility screenings, polymorphism, salt selection, crystallization test, formulation for animal dosing, or phase I formulation strategy set-up…

Deeptope

DRF – Institut Joliot /SIMoS Bât. 152 Pièce 35A Gif-sur-Yvette Cedex , F-91191 FranceAccelerate and de-risk the development of Biotech/Pharma therapeutic antibodies with an integrated optimization solution to achieve expected characteristics in less than 3 months.

Deeptope

DRF – Institut Joliot /SIMoS/Bât. 152 Pièce 35A Gif-sur-Yvette Cedex , F-91191 FranceAccelerate and de-risk the development of Biotech/Pharma therapeutic antibodies with an integrated optimization solution to achieve expected characteristics in less than 3 months.

DBI

Chemin de Mazerolles IDRON, 64320 France, EuropeDBI offers high potency products and manufacturing services for APIs, cytotoxics, peptides, proteins, monoclonal antibodies, and vaccines.

Diaclone

6 Rue du Dr Jean-François Xavier Girod Besançon, France, 25000 FranceOur expertise and know-how make us a trusted partner for custom product development & manufacture, Monoclonal Antibodies, ELISPOT, Bulk & OEM product supply.

European Sarcoma & Tumour Bank

France

ESPCI ParisTech

10 rue Vauquelin Paris, 75231 FranceESPCI ParisTech offers laboratories focused in various areas including organic chemistry, neurobiology, and genetics.

Emka Technologies

59, bd. Général Martial Valin 75015 Paris - FranceEmka TECHNOLOGIES develops, manufactures and sells hardware and software for studies in physiology, pharmacology and toxicology.

Emka Technologies

59, bd. Général Martial Valin Paris, 75015 FranceEmka TECHNOLOGIES develops, manufactures and sells hardware and software for studies in physiology, pharmacology and toxicology.

Epsilon Chimie

450 rue Antoine Lavoisier Kergaradec III, Brest-Guipavas 29490 FranceEpsilon Chimie supplies chemical intermediates and offers custom synthesis and structural analysis services.

EVIC International

51, avenue de Paris 94300 VINCENNES FranceIn 1969, Pr Philippe Masson creates Evic Ceba, laboratory located in Bordeaux, France, designated to pharmacological and toxicological experiments. The success of this first company and the expertise of its scientists naturally lead to the extension of the know-how to the global exploration of ingredients and products from the pharmaceutical, cosmetic, chemical and food fields: in 1987, creation of Evic Idec, clinical research organization on healthy subjects; in 1991, foundation of in vitro / ex vivo department (Evic Bio). In 2000 Evic Ceba becomes Evic France and expands its capacities abroad. In a world of internationalisation of the needs of the industry and globalisation of the markets, Evic France enlarges its service offer and creates with local partners research and evaluation centres in Brazil, Romania, Italy, Spain, China, thus introducing the renown “Evic” label. To optimize this new network of laboratories, EVIC International is created in 2005, meant to manage independently the group organisation and functioning. The purpose of EVIC International is to coordinate and harmonize the activity of the companies and induce them on a common level of excellence.

ExonHit Therapeutics

Paris, FranceExonHit Therapeutics provides clinical validation, diagnostic tests, and RNA splicing.

ExonHit Therapeutics

Paris, Île-de-France FranceExonHit Therapeutics provides clinical validation, diagnostic tests, and RNA splicing.

Eurofins Biomnis

17/19 Avenue Tony Garnier Lyon, 69007 FranceEurofins Biomnis is a member of the Eurofins Clinical Diagnostics France network of laboratories. This network pools a wide variety of disciplines together to create comprehensive, innovative clinical diagnostics solutions, embracing everything from clinical research to hyperspecialised clinical pathology. Specialised medical pathology Eurofins Biomnis focuses mainly on specialised pathology testing, which requires highly skilled expertise, and which cannot be performed in routine private or hospital-based laboratories. Eurofins Biomnis specialises in all areas of pathology and testing is performed using the most recent and cutting-edge techniques, which necessitate complex calibrations and validations, highly qualified experts and sophisticated equipment. Clinical trials The Clinical Trials Department at Eurofins Biomnis was created in 1998, and runs clinical studies and develops assay methods for the pharmaceutical industry.

Eurofins Discovery - comprised of Eurofins Cerep, Eurofins Panlabs, DiscoverX Corporation, DiscoverX Products LLC, Pharmacology Discovery Services & Eurofins Beacon Discovery, Inc.

Le Bois L'évêque Celle L'Evescault, 86600 FranceFor more than 40 years, Eurofins Discovery has been a trusted CRO supporting global Drug Discovery clients from Target ID through to Candidate Selection. Eurofins Discovery was built by bringing together the market leading drug discovery expertise of Panlabs, Cerep, DiscoverX, EMD Millipore's Discovery & Development, Eurofins Integrated Discovery Ltd UK, Villapharma Research, Eurofins Beacon Discovery, Inc. and Pharmacology Discovery Services (a Partner Lab for in vivo) to offer a comprehensive package of drug discovery products and services, including in vitro assays, cell-based phenotypic assays, safety & efficacy, ADME-Tox, chemistry and custom proteins, assay development and in vivo services. This partnership grants our clients access to a broad portfolio of drug discovery products and services to help rapidly advance their drug candidates to the clinic.

Eurofins Discovery - comprised of Eurofins Cerep, Eurofins Panlabs, DiscoverX Corporation, DiscoverX Products LLC, Pharmacology Discovery Services & Eurofins Beacon Discovery, Inc.

Le Bois L'Evêque Celle L'Evescault, 86600 FranceFor more than 40 years, Eurofins Discovery has been a trusted CRO supporting global Drug Discovery clients from Target ID through to Candidate Selection. Eurofins Discovery was built by bringing together the market leading drug discovery expertise of Panlabs, Cerep, DiscoverX, EMD Millipore's Discovery & Development, Eurofins Integrated Discovery Ltd UK, Villapharma Research, Eurofins Beacon Discovery, Inc. and Pharmacology Discovery Services (a Partner Lab for in vivo) to offer a comprehensive package of drug discovery products and services, including in vitro assays, cell-based phenotypic assays, safety & efficacy, ADME-Tox, chemistry and custom proteins, assay development and in vivo services. This partnership grants our clients access to a broad portfolio of drug discovery products and services to help rapidly advance their drug candidates to the clinic.

E-Zyvec

80 rue du Dr Yersin RDC-A Loos, 59120 FranceFounded in 2016, e-Zyvec is a biotech start-up specialized in genetic engineering, spinning-off the university of Lille and the CNRS. Following a Seed funding series closed in 2018 (with Autonomie et Solidarité, Nord France Amorçage & private investors) the start-up moved in the Parc Eurasanté in a fully refurbished facility. e-Zyvec, a company devised by scientists to assist scientists, provides integrated services in molecular biology to biologists from the academic or the private sector. This service is accessible worldwide through the dedicated web portal!

ENTEROSYS SAS

Prologue Biotech, Quai C7/C8 516, rue Pierre et Marie Curie Labège, Midi-Pyrénées, 31670 FranceEnterosys has developed a solid expertise in quantification of nitric oxide (NO) and hydrogen peroxide (H2O2) in real time by amperometry. This technology makes it possible to quantify, in an absolute manner, the release of these two biomarkers of oxidative stress in different biological models: primary cell cultures or cell lines in 2 or 3D, in organs or in vivo in anesthesied animals. We offer different applications: - evaluation of the antioxidant capacities of your assets (chemical molecules, natural extracts, formulations ...) - comparative study of the efficacy of assets compared to a standard or bioactive molecule already on the market - development of stress models with an innovative approach for the creation of new lines of cosmetics (sensitizing agents, pollution, infectious agents, atopic dermatitis, hormonal imbalance ...)

ESBB

20 Boulevard du Roi René Aix-en-Provence, 13100 FranceMisson & Goals The mission of ESBB is to advance the field of biobanking in support of research relating to healthcare, agriculture and the environment. The goals of ESBB are as follows: Identify problems in the biobanking field and provide solutions. Encourage high professional standards in biobanking. Provide high value membership services for key actors in the biobanking field. Encourage participation from a wide range of repositories across the EMEA region. Provide a strong united voice for biobankers in the region, to influence development in their field.

Essais+

1 Place du 8 mai 1945 Hénin-sur-Cojeul, Hauts-de-France, 62128 FranceEssais+, a dynamic and growing company. Essais+, a private family and independent company, became a major actor in the development of agriculture projects with international companies. During all these years, we constantly innovated in order to adapt the demands of our customers for the agricultural market. 10% of the annual capital is devoted to investments, protection of operators and respect of the environment.

Episkin

4, Rue Alexandre Fleming 69366 - LYON FranceEpiskin provides our worldwide clients RELIABLE AND RELEVANT IN VITRO TOOLS FOR SAFETY AND EFFICACY PROFILING Episkin, world leader in tissue engineering, is partnering with cosmetical, pharmaceutical and chemical industries to develop relevant and reliable safety and efficacy tests for decision making during research and development phases. Some screening tests are already referenced and validated as alternatives to animal use, and others are in the process of validation. Developed in the early 90, our unique cell culture process allows to mass produce in vitro various models of reconstructed human tissues with well characterized histology, functionality and ultrastructure features. The production unit is geared to serve every week our clients with thousands of human tissues.

Eurofins EAG Materials Science, LLC

94, chemin de la Peyrette 31170 Tournefeuille, FranceEurofins EAG Materials Science, LLC has a long history, dating back to the birth of the company in 1978 in California, as Charles Evans & Associates. Over the years we have expanded from a single location offering SIMS only to having over 200 employees offering over 30 different services via 14 locations in 8 different countries. The original focus of the company was supporting semiconductor manufacturing but now we also work with multiple further industries beyond semiconductors, including: solar/PV, lighting, photonics, energy storage, aerospace & defense, medical devices, raw materials, glass, polymers and plastics and consumer products. EAG's analytical expertise is what enables us to help our clients to meet their goals. Our on-demand analytical testing services can help streamline R&D, solve urgent problems during manufacturing and help resolve materials related issues in the global supply chain, both within and between organizations.

ELITech

12-12 bis rue Jean Jaurès 92800 Puteaux • FranceELITech offers manufacturing and distribution of in vitro diagnostic equipment and reagents.

ELITech

Puteaux, Île-de-France, 92800 FranceELITech offers manufacturing and distribution of in vitro diagnostic equipment and reagents.

EXCILONE

Université Rennes 1 Plateforme H2P2 2 avenue du Pr Léon Bernard RENNES CEDEX, 35043 FranceSince its creation Excilone has developed an unique expertise in sample’s analysis through the image or the molecular content. We use what we sell and we sell what we use Our dual approach of service provider as well as vendor of our solutions brings us an unequaled expertise on the performance and the use of our products that benefit our customers. Pharmaceutical and cosmetic companies, academic research labs and other CROs are all users of our services. Our R&D department allows us to regularly supplement our offer as recently with the isolation, characterization and analysis of extracellular vesicles from any type of sampling (blood, urine, milk, tissues, …). Our services are aimed at all private and academic labs that need to use operational analysis techniques without having to invest in expensive devices which also are time consuming to set protocols and to validate them. To reply to the needs of the scientific community about the analysis of samples through images or molecular content Excilone offers a wide range of services in Microgenomics, Nanogenomics, and Cellular Imaging. As the understanding of biological phenomena is now done at the scale of the cell, Excilone presents you the excellence in epsilon quantity.

EXCILONE

INRAE Domaine de Vilvert 4, avenue Jean Jaurès Bat221 JOUY EN JOSAS, 78352 FranceSince its creation Excilone has developed an unique expertise in sample’s analysis through the image or the molecular content. We use what we sell and we sell what we use Our dual approach of service provider as well as vendor of our solutions brings us an unequaled expertise on the performance and the use of our products that benefit our customers. Pharmaceutical and cosmetic companies, academic research labs and other CROs are all users of our services. Our R&D department allows us to regularly supplement our offer as recently with the isolation, characterization and analysis of extracellular vesicles from any type of sampling (blood, urine, milk, tissues, …). Our services are aimed at all private and academic labs that need to use operational analysis techniques without having to invest in expensive devices which also are time consuming to set protocols and to validate them. To reply to the needs of the scientific community about the analysis of samples through images or molecular content Excilone offers a wide range of services in Microgenomics, Nanogenomics, and Cellular Imaging. As the understanding of biological phenomena is now done at the scale of the cell, Excilone presents you the excellence in epsilon quantity.

EXCILONE

6 Rue Blaise Pascal Élancourt, Île-de-France, 78990 FranceSince its creation Excilone has developed an unique expertise in sample’s analysis through the image or the molecular content. We use what we sell and we sell what we use Our dual approach of service provider as well as vendor of our solutions brings us an unequaled expertise on the performance and the use of our products that benefit our customers. Pharmaceutical and cosmetic companies, academic research labs and other CROs are all users of our services. Our R&D department allows us to regularly supplement our offer as recently with the isolation, characterization and analysis of extracellular vesicles from any type of sampling (blood, urine, milk, tissues, …). Our services are aimed at all private and academic labs that need to use operational analysis techniques without having to invest in expensive devices which also are time consuming to set protocols and to validate them. To reply to the needs of the scientific community about the analysis of samples through images or molecular content Excilone offers a wide range of services in Microgenomics, Nanogenomics, and Cellular Imaging. As the understanding of biological phenomena is now done at the scale of the cell, Excilone presents you the excellence in epsilon quantity.

Eurosafe

EUROSafe Parc d'affaires de la Bretèche Bldg A4 and Bât B1 Saint-Grégoire, Ille-et-Vilaine, 35760 FranceEurosafe offers in vitro -pharmacology, -ADME, including skin/intestinal permeability studies, blood brain barrier studies, genotoxicity, cytotoxicity, metabolite characterization, and protein binding studies. -Tox services, in vitro evaluation of the safety, security, sensibilisation (H-Clat, DPRA- sens-is)DPRA, H-Clat, Sens-is, for cosmetic ingredients and provides solutions allowing faster and cost-effective drug discovery by identifying at early stages the most promising drug candidates

Ercé plasturgie

ZA du Borrey -F-01100 MARTIGNAT FranceErcé plasturgie specializes in liquid dosing systems and primary packaging.

Explicyte

229 cours de l'Argonne Bordeaux, 33000 FranceExplicyte was launched by ImmuSmol – a company located in Bordeaux and founded in 2012 by immunologist Alban Bessede with the support of Schiever group (over 1,3 billion euros in annual turnover) and François Ichas a well-recognized cellular biologist. Since 2013, ImmuSmol has been developing unique antibodies and immunodetection assays, as well as in vivo capabilities for the development of proprietary therapeutic antibodies. In 2016, ImmuSmol took the opportunity to launch Explicyte – a family brand of specialty preclinical services.

ETAP-Lab

2 Rue des Rochambelles Caen, Normandie, 14000 FranceETAP-Lab provides preclinical models and services in the fields of Dermatology and Neurology (Stroke + Neurodegenerative diseases). ETAP-Lab works for about 136 clients worldwide and performed more than 700 hundred studies. The company has strong expertise in the field of Dermatology research and offers a large portfolio of original in vivo rodent models such as chronic skin inflammation, ischemic ulceration, psoriasis, hyperkeratosis, wound healing, atopic dermatitis, actinic keratosis, skin cancer… ETAP-Lab is also leader in the field of preclinical stroke research with a unique model portfolio consisting of innovative and translational models proposed under the brand STROK@LLIANCE. It is the only CRO 100% dedicated to preclinical stroke research, The Strok@lliance Scientific Advisory Board is coordinated by a renowned scientist in the field of Stroke : Pr Denis Vivien (PhIND Laboratory, INSERM/Caen university). Also, ETAP-Lab provide both in vitro and in vivo services in the fields of Neurodegenerative diseases, namely Alzheimer's and Parkinson's diseases, based on its unique know-how in production of stable and soluble toxic oligomers (Amyloid-Beta 1-42 oligomers, Tau oligomers, Alpha-synuclein oligomers). With more than 2 decades of experience, ETAP-Lab has become a best-in-class service provider for top tier Pharma, Medical device and Agri-food companies and obtained ISO9001:v2015 certification for all its preclinical services. ETAP-Lab is listening to the needs of their clients to offer the most suited solution for products evaluation. Thus, our team is able to develop and customize relevant animal models with high translational value that fit to specific goals, from the proof-of-concept to the early development.

ETAP-Lab

13 Rue du Bois de la Champelle Vandœuvre-lès-Nancy, Grand Est, 54500 FranceETAP-Lab provides preclinical models and services in the fields of Dermatology and Neurology (Stroke + Neurodegenerative diseases). ETAP-Lab works for about 136 clients worldwide and performed more than 700 hundred studies. The company has strong expertise in the field of Dermatology research and offers a large portfolio of original in vivo rodent models such as chronic skin inflammation, ischemic ulceration, psoriasis, hyperkeratosis, wound healing, atopic dermatitis, actinic keratosis, skin cancer… ETAP-Lab is also leader in the field of preclinical stroke research with a unique model portfolio consisting of innovative and translational models proposed under the brand STROK@LLIANCE. It is the only CRO 100% dedicated to preclinical stroke research, The Strok@lliance Scientific Advisory Board is coordinated by a renowned scientist in the field of Stroke : Pr Denis Vivien (PhIND Laboratory, INSERM/Caen university). Also, ETAP-Lab provide both in vitro and in vivo services in the fields of Neurodegenerative diseases, namely Alzheimer's and Parkinson's diseases, based on its unique know-how in production of stable and soluble toxic oligomers (Amyloid-Beta 1-42 oligomers, Tau oligomers, Alpha-synuclein oligomers). With more than 2 decades of experience, ETAP-Lab has become a best-in-class service provider for top tier Pharma, Medical device and Agri-food companies and obtained ISO9001:v2015 certification for all its preclinical services. ETAP-Lab is listening to the needs of their clients to offer the most suited solution for products evaluation. Thus, our team is able to develop and customize relevant animal models with high translational value that fit to specific goals, from the proof-of-concept to the early development.

ETAP-Lab

13 rue du Bois de la Champelle Vandoeuvre-lès-Nancy, 54500 FranceETAP-Lab provides preclinical models and services in the fields of Dermatology and Neurology (Stroke + Neurodegenerative diseases). ETAP-Lab works for about 136 clients worldwide and performed more than 700 hundred studies. The company has strong expertise in the field of Dermatology research and offers a large portfolio of original in vivo rodent models such as chronic skin inflammation, ischemic ulceration, psoriasis, hyperkeratosis, wound healing, atopic dermatitis, actinic keratosis, skin cancer… ETAP-Lab is also leader in the field of preclinical stroke research with a unique model portfolio consisting of innovative and translational models proposed under the brand STROK@LLIANCE. It is the only CRO 100% dedicated to preclinical stroke research, The Strok@lliance Scientific Advisory Board is coordinated by a renowned scientist in the field of Stroke : Pr Denis Vivien (PhIND Laboratory, INSERM/Caen university). Also, ETAP-Lab provide both in vitro and in vivo services in the fields of Neurodegenerative diseases, namely Alzheimer's and Parkinson's diseases, based on its unique know-how in production of stable and soluble toxic oligomers (Amyloid-Beta 1-42 oligomers, Tau oligomers, Alpha-synuclein oligomers). With more than 2 decades of experience, ETAP-Lab has become a best-in-class service provider for top tier Pharma, Medical device and Agri-food companies and obtained ISO9001:v2015 certification for all its preclinical services. ETAP-Lab is listening to the needs of their clients to offer the most suited solution for products evaluation. Thus, our team is able to develop and customize relevant animal models with high translational value that fit to specific goals, from the proof-of-concept to the early development.

EGrenier

84 Rue Bechevelin Lyon, 69007 FranceMathematician Specialist of modeling (PKPD, RL, AI technics, mechanistic modeling, ...) http://perso.ens-lyon.fr/egrenier/ Professor at the Ecole Normale Supérieure of Lyon Former associate professor at Ecole Polytechnique phD, phD Habil

Elveflow

83 Avenue Philippe Auguste 75011 Paris FRANCEElveflow® focuses on the development of high performance and Plug and Play flow control systems fitted to microfluidic research. We provide the only microfluidic flow control systems using Piezo technology and that enable blazing fast flow changes in your microdevice. Our team develops microfluidic instruments with unrivaled performances in accordance to researchers’ needs. Our product line is built around the best seller OB1 flow controller and includes all that is needed to control your microfluidic chip. All our instruments can be controlled at once on the same computer, through our software or Standard Development Kits.

Elveflow

85 avenue philippe auguste France Paris, france, 75011 FranceElveflow® focuses on the development of high performance and Plug and Play flow control systems fitted to microfluidic research. We provide the only microfluidic flow control systems using Piezo technology and that enable blazing fast flow changes in your microdevice. Our team develops microfluidic instruments with unrivaled performances in accordance to researchers’ needs. Our product line is built around the best seller OB1 flow controller and includes all that is needed to control your microfluidic chip. All our instruments can be controlled at once on the same computer, through our software or Standard Development Kits.

Elveflow

172 Rue de charonne Paris 11, 75011 FranceElveflow® focuses on the development of high performance and Plug and Play flow control systems fitted to microfluidic research. We provide the only microfluidic flow control systems using Piezo technology and that enable blazing fast flow changes in your microdevice. Our team develops microfluidic instruments with unrivaled performances in accordance to researchers’ needs. Our product line is built around the best seller OB1 flow controller and includes all that is needed to control your microfluidic chip. All our instruments can be controlled at once on the same computer, through our software or Standard Development Kits.

Excelvision

Annonay, Auvergne-Rhône-Alpes, 07100 FranceExcelvision offers full service manufacturing of pharmaceutics and cosmetics.

Eurofins Optimed

Gières, Auvergne-Rhône-Alpes FranceEurofins Optimed offers clinical research services including clinical pharmacology, data management, and project management.

EUROPHARTECH

34 rue Henri Matisse - BP 23 Lempdes 63370 FranceEUROPHARTECH manufactures pharmaceuticals and food supplements.

Edelris

60, Avenue Rockefeller BioParc, Bioserra 1 Lyon, 69008 FranceHit Generation: Edelris offers premium services in Hit Generation: - Keymical Fragments: non-exclusive 3D fragments for Fragment-based lead discovery (FBLD/FBDD). These innovative compounds are tractable, Natural-by-Design (purely synthetic compounds accessible in a few reliable steps from commercially accessible starting material), and have proven successful in many FBS campaigns at clients'. See for example: https://doi.org/10.1016/j.bmcl.2019.126717 and http://practicalfragments.blogspot.com/2020/01/three-dimensional-fragments-revisited.html - Keymical Collections: non-exclusive 3D lead-like series of compounds for HTS. These innovative compounds are tractable, Natural-by-Design (purely synthetic compounds accessible in a few reliable steps from commercially accessible starting material), and have proven sucessful in many screening campaigns at clients'. See for example: H.Waldmann et al. Angew. Chem. Int. Ed. 2019, 58, 17016 – 17025 - EDEN (Edelris Discovery ENgine): based upon an in-house designed and produced screening collection of 1.5 million compounds from its Keymical Space, Edelris offers efficient ligand identification services using AS-MS (Affinity Selection - Mass Spectrometry), against biological targets from clients. Edelris has successfully screened dozen of targets ranging from enzymes, native GPCR, RNA, PPI... Clients screening decks can also be used, blinded if needed. - DEL by EDELRIS: DNA-encoded libraries for exclusive clients applications Hit-to-Lead, Lead Optimization: Edelris offers cost-efficient and track-proven medicinal chemistry services (Hit exploration, fast follow-up library synthesis, iterative optimization loops) towards an overall biological profile defined by the clients. See for example: https://doi.org/10.1021/acschembio.7b00708

European Synchrotron Radiation Facility

Grenoble, FranceEuropean Synchrotron Radiation Facility (ESRF) provides synchrotron radiation source for scientific research.

European Synchrotron Radiation Facility

Grenoble, Auvergne-Rhône-Alpes FranceEuropean Synchrotron Radiation Facility (ESRF) provides synchrotron radiation source for scientific research.

EVerZom

45 rue des Saints Pères Paris, Ile-de-France, 75006 FranceEverZom develops a new manufacturing platform of large-scale cGMP grade exosomes for research purposes and clinical studies based on a unique proprietary process. Our process, based on turbulence stimulation allows in average a 10-fold higher and a 10-fold faster increase in EV production per cell compared to starvation method for different cell lines. We also provide characterization services with an NTA, an Exoview, a Videodrop from Myriade and a flow cytometry platform.

Epithelix

18 chemin des Aulx CH-1228 Plan-Les-Ouates Genève SwitzerlandEpithelix provides in vitro human tissues, high throughput screening, and chemical testing. Epithelix Sàrl provides alternative in vitro solutions to animal experimentation for evaluating the effects of drugs in development and assess the toxicity of chemical compounds on the human respiratory tract. The company is the European leading provider of in vitro reconstituted human respiratory tissues and related services to leading academic research laboratories. Epithelix also supplies and supports Personal Care, Medical Device, as well as Chemical and Pharmaceutical. Epithelix developed a unique technology allowing reconstituted tissues to be maintained at a homeostatic state for a long period of time; in other words, the tissues resemble the native tissue both morphologically and functionally (see our products page). The company focused initially on the respiratory system and marketed MucilAir™, the only human respiratory epithelium model able to remain fully differentiated and functional for more than one year. This model is commercialized and available in US, Europe and Asia.

Epithelix

18 chemin des Aulx Plan-les-Ouates, Genève, 1228 SwitzerlandEpithelix provides in vitro human tissues, high throughput screening, and chemical testing. Epithelix Sàrl provides alternative in vitro solutions to animal experimentation for evaluating the effects of drugs in development and assess the toxicity of chemical compounds on the human respiratory tract. The company is the European leading provider of in vitro reconstituted human respiratory tissues and related services to leading academic research laboratories. Epithelix also supplies and supports Personal Care, Medical Device, as well as Chemical and Pharmaceutical. Epithelix developed a unique technology allowing reconstituted tissues to be maintained at a homeostatic state for a long period of time; in other words, the tissues resemble the native tissue both morphologically and functionally (see our products page). The company focused initially on the respiratory system and marketed MucilAir™, the only human respiratory epithelium model able to remain fully differentiated and functional for more than one year. This model is commercialized and available in US, Europe and Asia.

Epithelix

18 chemin des Aulx Plan-les-Ouate Plan les Ouates, Geneva, 1228 SwitzerlandEpithelix provides in vitro human tissues, high throughput screening, and chemical testing. Epithelix Sàrl provides alternative in vitro solutions to animal experimentation for evaluating the effects of drugs in development and assess the toxicity of chemical compounds on the human respiratory tract. The company is the European leading provider of in vitro reconstituted human respiratory tissues and related services to leading academic research laboratories. Epithelix also supplies and supports Personal Care, Medical Device, as well as Chemical and Pharmaceutical. Epithelix developed a unique technology allowing reconstituted tissues to be maintained at a homeostatic state for a long period of time; in other words, the tissues resemble the native tissue both morphologically and functionally (see our products page). The company focused initially on the respiratory system and marketed MucilAir™, the only human respiratory epithelium model able to remain fully differentiated and functional for more than one year. This model is commercialized and available in US, Europe and Asia.

EasyPanel

54 Rue Dunois Paris, 75013 FranceIntelligent and Automated Flow Cytometry Panel Design Platform.

French Atomic Energy Commission (CEA)

Bâtiment Le Ponant D 25, rue Leblanc Paris, 75015 FranceLe Commissariat à l’énergie atomique et aux énergies alternatives (CEA) est un organisme public de recherche à caractère scientifique, technique et industriel (EPIC).​ Acteur majeur de la recherche, du développement et de l'innovation, le CEA intervient dans le cadre de quatre missions : la défense et la sécurité, l'énergie nucléaire (fission et fusion), la recherche technologique pour l'industrie et la recherche fondamentale (sciences de la matière et sciences de l​a vie). S'appuyant sur une capacité d'expertise reconnue, le CEA participe à la mise en place de projets de collaboration avec de nombreux partenaires académiques et industriels.

Firmenich

Geneva, SwitzerlandFirmenich is in the perfume and flavor business and also provides organic synthesis and biotechnology services.

Fareva

80, Avenue de la grande armée Paris, 75017 FranceFareva offers contract manufacturing services including formulation, production, and filling.

Flash Therapeutics SAS

Centre de Recherche Langlade 3 Avenue Hubert Curien TOULOUSE, 31100 FranceFlash Therapeutics is a gene therapy company developing gene and cell-based therapies by leveraging its bioproduction continuum from research to clinic and its proprietary lentiviral platform including regular integrative lentiviral vectors (iLV) and its patented non-integrative LentiFlash® technology. Flash Therapeutics’ platform covers both gene-addition and gene-editing current needs, producing R&D to GMP grade batches to be used for therapy.

Flash Therapeutics SAS

3 rue des satellites - Canal Biotech 2 France Toulouse, Languedoc-Roussillon-Midi-Pyrénées, 31400 FranceFlash Therapeutics is a gene therapy company developing gene and cell-based therapies by leveraging its bioproduction continuum from research to clinic and its proprietary lentiviral platform including regular integrative lentiviral vectors (iLV) and its patented non-integrative LentiFlash® technology. Flash Therapeutics’ platform covers both gene-addition and gene-editing current needs, producing R&D to GMP grade batches to be used for therapy.

Fluidigm

1 Avenue de l’Atlantique Les Conquérants, Bat. Kilimandjaro Les Ulis, 91940 France

Forenap Pharma

27 rue du 4eme RSM Rouffach 68250 FranceForenap Pharma offers screening, toxicology, metabolism analytics, submission documents, pharmaceutical development, and exploratory studies.

Forenap Pharma

Rouffach, Grand Est, 68250 FranceForenap Pharma offers screening, toxicology, metabolism analytics, submission documents, pharmaceutical development, and exploratory studies.

FranceTissueBank

263, Via Nova Pole d'Excellence Jean-Louis FREJUS, Provence-Alpes-Cote-d'Azur, 83600 FranceLooking for samples of high-standards quality with reactivity, France Tissue Bank will answer to your needs France Tissue Bank is a tissue bioresources provider specialized in oncology and associated to Anatomo-Cyto-Pathology laboratories. FTB provides FFPE blocks, slide sets, liquid PAP smears and digital images to innovative companies with expertise in AI technology, imaging processes, diagnostic tests, drug development, ... Customized services such as medical expertise, special staining or molecular biology tests are offered to improve cancer treatment or development of new technics such as Artificial Intelligency.

Fasteris

Rue du Champ-Blanchod 4 Plan-les-Ouates, Geneva, 1228 SwitzerlandInventor of Next-Generation Sequencing technology and provider of NGS and Sanger DNA sequencing services. We service worldwide to private, academic, governmental and industrial research laboratories, as well as to biotechnology and pharma companies. Since 2012, we are provider of NGS services for medical diagnostics. - In 2013, Fasteris has joined the Swiss MediSupport network of medical diagnostic laboratories. - In 2015, Fasteris has become member of the SONIC Healthcare network. Sonic Healthcare is a global healthcare company with reputation for excellence in laboratory medicine & pathology, radiology & diagnostic imaging, as well as primary care medical services. - Effective September 3rd, 2020, Geneva-based Fasteris SA has joined forces with its medical genetics partners in Lausanne to create a new company, re-named Genesupport SA. - Like was before, NGS and Sanger sequencing services will be provided for "Life Science" under the brand of "Fasteris". We have taken action to ensure that same quality, fast turn-around times and same dedication to our Life Science services and partners will be maintained and stay guaranteed. - Our "Medical genetics services" will be provided under the market brand "Genesupport".

FNAMS - Federation Nationale des Agriculteurs Multiplicateurs de Semences

74 Rue Jean-Jacques Rousseau Paris-1ER-Arrondissement, Île-de-France, 75001 FranceQui sommes nous? Une fédération au service des agriculteurs multiplicateurs depuis plus de 50 ans ! La FNAMS (Fédération Nationale des Agriculteurs Multiplicateurs de Semences) est une organisation professionnelle agricole spécialisée dans la multiplication des semences. Elle représente les 18 000 agriculteurs multiplicateurs de semences français. Sa mission est de promouvoir la production de semences française et défendre les intérêts des agriculteurs multiplicateurs de semences.

Floralis

6, Allée de Bethléem Gières, 38610 FranceFloralis, a subsidiary of the University Joseph Fourier, assists in technology transfer by offering proof of concept, intellectual property, and licensing support services.

Filab

13 Rue Pauline Kergomard Dijon, Bourgogne Franche-Comté, 21000 FranceFILAB is a high-end laboratory that provides pharmaceutical industrie with : - Chemical Analysis by ICP-MS / ICP-AES, GC-MS, LC-MSMS, NMR, IC, XRD, SEM-EDX, BET, granulometry, UV, FTIR... - Analytical Development - Materials Characterization - Troubleshooting - R&D support services

Filab

13 RUE PAULINE KERGOMARD France DIJON, Veuillez sélectionner, 21000 FranceFILAB is a high-end laboratory that provides pharmaceutical industrie with : - Chemical Analysis by ICP-MS / ICP-AES, GC-MS, LC-MSMS, NMR, IC, XRD, SEM-EDX, BET, granulometry, UV, FTIR... - Analytical Development - Materials Characterization - Troubleshooting - R&D support services

Fluofarma

Pessac, FranceFluofarma (CRO Research) is a leading company in High Content Screening (HCS) providing services to improve the drug discovery potential of its clients. The Fluofarma divisions provide the most complete High Content Screening service offer on the market.

Fluofarma

2 Rue Robert Escarpit Pessac, 33600 FranceFluofarma (CRO Research) is a leading company in High Content Screening (HCS) providing services to improve the drug discovery potential of its clients. The Fluofarma divisions provide the most complete High Content Screening service offer on the market.

GeneCreek

326 chemin de Gatipet La Frette, 38260 FranceGeneCreek meets the complex interplay of human metabolism and microbiota up-front, generating leads from exploratory human in vivo studies, thus creating a rationalized, reduced risk development workflow for probiotic- and pharmaceutical solutions.

Genomic Vision

80 Rue des Meuniers Bat E Bagneux, Île-de-France, 92220 FranceGenomic Vision is a molecular diagnostics and technology company specialized in the development of single DNA detection tools for research and in vitro diagnostics. The company was created in 2004 by the founder-researcher Aaron Bensimon, a doctor in molecular biology and head of the Genomic Instability Unit of the Institut Pasteur at the time. The company’s technology combines Molecular Combing; isolation and linearization genomic DNA, with a unique targeting and detection strategy, the Genomic Morse Code. Molecular Combing is a proprietary technique to isolate and stretch individual DNA molecules over a chemically modified glass surface. The Genomic Morse Code fluorescently labels the target loci providing a characteristic colour-coded pattern to clearly visualize genes in the loci of interest. This innovative approach is used in research and diagnostics to detect structural variations in the genome which are potentially the origin of numerous debilitating or life threatening pathologies. Genomic Vision aims to bring a new perspective to genetic testing and biomarker discovery by bridging the gap between examining large chromosomal abnormalities and small sequence changes. GV's technology fulfills unmet diagnostic and research needs by enabling the rapid and accurate identification of large DNA rearrangements implicated in genetic diseases and cancer. Genomic Vision's mission is to create new standards in Oncogenetic and genetic disease testing for more efficient, individualized, predictive and preventive health care management. The Company is developing a solid portfolio of tests that notably target breast cancer and cancer of the colon. Since 2013, the Company has marketed the CombHeliX® FSHD test for identifying a myopathy that is difficult to detect, Facio-scapulo-humeral dystrophy (FSHD), in the United States thanks to a strategic alliance with Quest Diagnostics, the American leader in diagnostic laboratory tests. In France, the FSHD test is used at La Timone Hospital in Marseille, since 2010. Genomic Vision has been listed on Compartment C of Euronext Paris since April 2014. The company’s headquarters and research facilities are located in Bagneux (Paris region), France.

Genomic Vision

80-84 Rue des Meuniers, Bat E, Green Square Bagneux, Ile-de-France, 92220 FranceGenomic Vision is a molecular diagnostics and technology company specialized in the development of single DNA detection tools for research and in vitro diagnostics. The company was created in 2004 by the founder-researcher Aaron Bensimon, a doctor in molecular biology and head of the Genomic Instability Unit of the Institut Pasteur at the time. The company’s technology combines Molecular Combing; isolation and linearization genomic DNA, with a unique targeting and detection strategy, the Genomic Morse Code. Molecular Combing is a proprietary technique to isolate and stretch individual DNA molecules over a chemically modified glass surface. The Genomic Morse Code fluorescently labels the target loci providing a characteristic colour-coded pattern to clearly visualize genes in the loci of interest. This innovative approach is used in research and diagnostics to detect structural variations in the genome which are potentially the origin of numerous debilitating or life threatening pathologies. Genomic Vision aims to bring a new perspective to genetic testing and biomarker discovery by bridging the gap between examining large chromosomal abnormalities and small sequence changes. GV's technology fulfills unmet diagnostic and research needs by enabling the rapid and accurate identification of large DNA rearrangements implicated in genetic diseases and cancer. Genomic Vision's mission is to create new standards in Oncogenetic and genetic disease testing for more efficient, individualized, predictive and preventive health care management. The Company is developing a solid portfolio of tests that notably target breast cancer and cancer of the colon. Since 2013, the Company has marketed the CombHeliX® FSHD test for identifying a myopathy that is difficult to detect, Facio-scapulo-humeral dystrophy (FSHD), in the United States thanks to a strategic alliance with Quest Diagnostics, the American leader in diagnostic laboratory tests. In France, the FSHD test is used at La Timone Hospital in Marseille, since 2010. Genomic Vision has been listed on Compartment C of Euronext Paris since April 2014. The company’s headquarters and research facilities are located in Bagneux (Paris region), France.

Genoskin

1 place Pierre Potier Centre Pierre Potier Toulouse, France, 31100 FranceGenoskin is a Partner Research Organization (PRO) with unique expertise in skin & immunology. We provide the pharmaceutical as well as the cosmetic industries with proprietary ex vivo human skin platforms representing last-line screens, under laboratory conditions, prior to clinical evaluation. Our technologies only include natural human skin obtained from screenable patient cohorts. The skin is maintained in a living and functional state for several days in order to help you obtain relevant data. Our platforms are suitable for efficacy and toxicity assessment and for different routes of administration such as epicutaneous application, subcutaneous injection or systemic application.

Gemacbio

25, av. Jean Léon Laporte Anglet, 64600 FranceGemacbio offers immunogen synthesis and antibody production services.

GTP Technology

Batiment Gould 52 l'Occitane Labège, Languedoc-Roussillon-Midi-Pyrénées, 31670 FranceGTP Technology is a CRO with 17 years experience in providing customized solutions for production of recombinant proteins.

Groupe Dermscan

114 boulevard du 11 novembre 1918 - 69100 Villeurbanne - FRANCELaboratoire Dermscan provides in vitro toxicity studies of cell models as well as in vivo efficacy and tolerance trials. Operating for over 23 years in France, and abroad, we can draw on a panel of over 15,000 volunteers and a host of devices and methods to quantify and visualise the impact of your raw materials and finished products. Our R&D Department provides a technological monitoring service as a vital component in the establishment of innovative protocols. Working in compliance with standards and good clinical practice (GCP), we first achieved ISO 9001 certification over 10 years ago, in our bid to offer you top-quality service and bring full satisfaction in terms of responsiveness, adaptability and meeting deadlines.

GenomeQuest

147, Avenue Paul Doumer 92500 Rueil Malmaison FranceGenomeQuest provides large-scale genomic software applications.

Galenix

Saint Jean D'Illac, FranceGalenix provides API production, formulation, analytical development, quality control, clinical manufacturing, and packaging.

Genosphere Biotechnologies

2 rue des Gravilliers 75003 Paris FRANCEGenosphere Biotechnologies provides custom peptides, antibodies, genes, and sequencing services.

GenesisCrest Infotech

Campus Merieux Marcy l’Etoile Metropolis of Lyon, 69280 FranceGenesisCrest is a life sciences consulting firm that help clients in medtech and lifescience businesses to improve and effectively meet the industry challenges by offering a selective suite of services including R&D due-diligence, market research, scientific writing, and medical communication services. Our other extended services include competitive intelligence, In-licensing support, KOL management, regulatory, reimbursement, and market insights to help clients develop successful R&D portfolio, product strategies and sound knowledge of industry as a whole. To streamline the business outcomes and delivery expectations, our operations are supported by ISO 9001:2015 certified management system.

Genomnis

Hôtel Technologique, 45 rue Frédéric Joliot-Curie – CS 10002 Technopôle de Château-Gombert MARSEILLE, 13382 FranceDuring the last 10 years, medical genetics has drastically changed with the emergence of new sequencing technologies. It is thus now possible to sequence individual genomes in few hours. The challenge is therefore not anymore to generate the data but to efficiently identify disease-causing mutations among millions of variations: the "search a needle in a haystack" challenge. Thanks to a fruitful partnership with experts from renown academic bioinformatics research teams from the Aix-Marseille University (AMU) and the French National Institute of Health and Medical Research (Inserm), the Genomnis company is providing the most efficient systems to predict the pathogenicity of mutations from any human gene. The Human Splicing Finder system allows the identification of splicing signals and the impact of mutations on these signals, while the UMD-Predictor system is dedicated to the prediction of exonic substitutions. Genomnis is also providing services to assist you to design your experiments and analyze data. Our vision is to provide you the power of bioinformatics coupled with the experience of genetics experts to simplify your genomics journey.

Greenpharma

3, allée du Titane Orléans, 45100 FranceGreenpharma is specialized in natural products and their valorization cosmetics, food, pharmacy, phytosanitary and veterinary industries. We provide molecules and libraries for R&D and cosmetic active ingredients. Our services include analytical, computational and medicinal chemistry, cosmetic formulation and R&D project management. Furthermore, we have a multiple process pilot extraction platform including supercritical CO2 and subcritical water. Greenpharma is also the owner of the following brand: - ambinter.com, a website for molecule procurement with a searchable database of 38 million of references - Prestwick Chemical Library with off-patent drugs from FDA, EMEA,... for drug repositioning

GENFIT

Parc Eurasanté 885, Avenue Eugène Avinée 59120 Loos FranceGENFIT is focused on the development of innovative therapeutic and diagnostic solutions for prevention and treatment of diabetes and related disorders.

Gattefosse

Lyon, FranceGattefosse specializes in the creation, development, manufacture, and marketing of specialty ingredients and innovative formulation solutions for the Health and Beauty industries.

Genethon

1bis, rue de l’Internationale – Évry, 91002 FranceGenethon focuses their efforts in developing new vector and plasmid designs and contructing them in the application of gene therapy studies. Their expertise includes bioprocess development, bioanalytical development, and sample storage.

Genexion

29, Quai du Mont-Blanc-PO Box 133 Geneva 21, CH-1211 SwitzerlandGenexion offers development of biopharmaceutical products specifically targeting chronic inflammatory and autoimmune disease.

Galderma

Les Templiers - 2400, route des Colles Sophia Antipolis, Biot 06410 FranceGalderma focuses on the drug development for the therapeutic areas of skin diseases as well as an array of genome analysis, screening, imaging, and pharmacokinetic/pharmakodynamic services.

Givaudan

5, Chemin de la Parfumerie Vernier, 1214 SwitzerlandAs the world’s leading flavour and fragrances company, we unveil the tastes and scents that suit you best, and that you love most.

GenoSplice Technology

4, rue Pierre Fontaine Evry, 91058 FranceGenoSplice Technology offers next generation sequencing and microarray data analysis, with specific expertise in alternative splicing.

Galapagos

Romainville, FranceGalapagos provides disease models, target discovery and screening, compound libraries, and medicinal chemistry.

GenEvolutioN

2-8 Route de Rouen Porcheville, 78440 FranceGenEvolutioN®, a specialist in in vitro toxicology and in vitro genetic toxicology, is developing an innovative technique for their clients: the telomere / centromere micronucleus test differentiating the aneugene and clastogenic effect. This technique that we develop, coupled with our know-how, allows our highly experienced employees to significantly reduce the delivery time of study results (saving up to 4 weeks), while respecting quality and giving our customers the benefit of our personalized support in their projects. Specialist for genotoxicity of plant extractc (herbal medecine, and cosmetic ingredient), in standard Ames test , and using treat and wash method.

GenEvolutioN

8 Rue de Rouen 2-8 rue de Rouen Porcheville, 78440 FranceGenEvolutioN®, a specialist in in vitro toxicology and in vitro genetic toxicology, is developing an innovative technique for their clients: the telomere / centromere micronucleus test differentiating the aneugene and clastogenic effect. This technique that we develop, coupled with our know-how, allows our highly experienced employees to significantly reduce the delivery time of study results (saving up to 4 weeks), while respecting quality and giving our customers the benefit of our personalized support in their projects. Specialist for genotoxicity of plant extractc (herbal medecine, and cosmetic ingredient), in standard Ames test , and using treat and wash method.

Genoscreen

Campus de l'Institut Pasteur de Lille Bâtiment Guérin-4th floor 1 rue du Pr Calmette Lille, 59000 FranceGenoscreen offers sequencing, genotyping, and bioinformatics services.

Genoscreen

1, rue du Professeur Calmette Lille, Hauts-de-France, 59000 FranceGenoscreen offers sequencing, genotyping, and bioinformatics services.

Gamma Imaging Applications (GAIA) - Université Grenoble Alpes UGA

Faculté de Médecine / Pharmacie, Site Santé, Domaine de la Merci 23 avenue Maquis du Grésivaudan, 4ème étage, Bâtiment Jean Roget La Tronche, Rhone - Alpes, 38700 FranceGAIA - Gamma Imaging Applications The small animal nuclear imaging platform GAIA (Gamma Imaging Applications) is located in the Laboratory of Bioclinical Radiopharmaceuticals. Over the past 30 years, this laboratory developed a unique expertise in the field of radiopharmaceuticals, including in the selection of the targets to be imaged, the synthesis of ligands, their radiolabeling, their biological evaluations and ultimately the realization of clinical trials. Areas of application include oncology, metabolism, cardiology and neurology. Thanks to the imaging platform GAIA, these well recognized competences are now accessible to industrial as well as academic partners, either as collaborations or services. • The evaluation of the pharmacokinetic and biodistribution of a compound of interest. To fulfill these objectives, the GAIA platform performs the radiolabeling and biological evaluation of the compound of interest. These evaluations can be conducted in various animal models. • The use of a well validated SPECT or PET radiotracer for the characterization of an animal model of interest, or for the evaluation of a new therapeutic compound. To fulfill these objectives, the GAIA platform performs all the biological evaluations. Indeed, many radiotracers are already available, and multiple isotope imaging can be performed. Examples of such studies include the follow up of tumor growth, the evaluation of brain perfusion, as well as the assessment of myocardial perfusion and function.

Gamma Imaging Applications (GAIA) - Université Grenoble Alpes UGA

Faculté de Médecine / Pharmacie, Site Santé, Domaine de la Merci 23 avenue Maquis du Grésivaudan, 4ème étage, Bâtiment Jean Roget La Tronche, Rhone - Alpes, 38700 FranceGAIA - Gamma Imaging Applications The small animal nuclear imaging platform GAIA (Gamma Imaging Applications) is located in the Laboratory of Bioclinical Radiopharmaceuticals. Over the past 30 years, this laboratory developed a unique expertise in the field of radiopharmaceuticals, including in the selection of the targets to be imaged, the synthesis of ligands, their radiolabeling, their biological evaluations and ultimately the realization of clinical trials. Areas of application include oncology, metabolism, cardiology and neurology. Thanks to the imaging platform GAIA, these well recognized competences are now accessible to industrial as well as academic partners, either as collaborations or services. • The evaluation of the pharmacokinetic and biodistribution of a compound of interest. To fulfill these objectives, the GAIA platform performs the radiolabeling and biological evaluation of the compound of interest. These evaluations can be conducted in various animal models. • The use of a well validated SPECT or PET radiotracer for the characterization of an animal model of interest, or for the evaluation of a new therapeutic compound. To fulfill these objectives, the GAIA platform performs all the biological evaluations. Indeed, many radiotracers are already available, and multiple isotope imaging can be performed. Examples of such studies include the follow up of tumor growth, the evaluation of brain perfusion, as well as the assessment of myocardial perfusion and function.

Gentaur

9, rue Lagrange, 75005 Paris, FranceGentaur is a supplier of life science research products.

GEG-Tech

27 Avenue du Québec, 91140 Villebon-sur-Yvette, France France Villebon-sur-Yvette, Île-de-France, 91140 FranceGEG-tech R&D team is focused on innovation in gene transfer tools and constantly innovate to improve lentiviral vector features, capabilities and safety. We aim at creating new tools which take every advantage of the lentivirus biology.

GenoSafe

Evry, FranceGenoSafe offers molecular analysis, immune response characterization, quality control of gene therapy products, and cell line/stem cell characterization.

Genewave

172 rue de Charonne Le Dorian B2 75011 Paris, FranceGenewave is a development-stage diagnostics company that provides information to curb the spread of hospital-acquired infections and anti-microbial resistance.

GenOway

31 Rue Saint-Jean-de-Dieu Lyon, Auvergne-Rhône-Alpes, 69007 FrancegenOway develops customized, highly physiologically relevant genetically modified rodent models including conditional and constitutive knockout, knockin and humanized transgenic mice and rats.

HUMAN CELL DESIGN

1 Pl. Pierre Potier Entree B Toulouse, 31100 FranceCell services, Human cells and assay development. Univercell-Biosolutions is now HUMAN CELL DESIGN.

HUMAN CELL DESIGN

1 Place Pierre Potier BP 50624 Toulouse, Occitanie, 31000 FranceCell services, Human cells and assay development. Univercell-Biosolutions is now HUMAN CELL DESIGN.

Human HepCell

184 Rue du Faubourg Saint Antoine Hôpital Saint Antoine Paris, 75012 FranceHuman HepCell is a preclinical Contract Research Organization specialized in liver pathologies (fibrosis, HCV). Human HepCell is specialized in the evaluation of molecules on human normal and pathological cells and tissues.

Holopharm

Val-de-Reuil, 27100 FranceOur dynamic and responsive team has more than 15 years of experience in pharmaceutical development and provides reliable and efficient solutions for the biocompatibility and stability of your products. Holopharm specializes in formulation and analytical development and develops batches from 1g to pilot size

Holopharm

to Innovation Pharmaparc II , Val-de-Reuil, 27100 FranceOur dynamic and responsive team has more than 15 years of experience in pharmaceutical development and provides reliable and efficient solutions for the biocompatibility and stability of your products. Holopharm specializes in formulation and analytical development and develops batches from 1g to pilot size

Hybrigenics Services

1 Rue Pierre Fontaine Genopole Biocluster Campus 3 Évry, Île-de-France, 91058 FranceHybrigenics Services is a complete service provider of cutting-edge technologies dedicated to the study of proteins and their interactions in 35+ organisms and any research thematic. We offer three main lines of services: • Interactions Discovery: ULTImate Y2H™ to discover novel protein-protein interactions in various tissues/cell types o Several adapted versions allow to identify interactions with transmembrane proteins, DNA and RNA o Associated services: Interaction Domain Mapping, Low binders, super binders • Drug Discovery Services (Adapted from ULTImate Y2H) o Target deconvolution: ULTImate YChemH™ to identify on- and off-targets of small bioactive molecules - mechanism of action, polypharmacology, drug repositioning, prediction of toxicity o Protein-protein interactions induced by molecular glues (protein stabilization, targeted protein degradation) • Nanobody® (or Synthetic Antibodies, VHH) to select and validate high-affinity single-domain antibodies (Hybribody™) - for IF, ELISA, high-resolution microscopy, video-microscopy, target inhibition applications but also for diagnosis and therapeutic purposes Our optimized screening platform in yeast enables the identification of the protein partners of proteins, DNA sequences, RNA and small molecules of therapeutic interest. Highly complex protein domain libraries, prepared from any cell type or tissue, are screened to saturation to identify partners and their interacting domains using a transcriptional read-out. Sophisticated bioinformatics analysis allows to attribute confidence scores to each interaction. With more than 3,200 academic and industrial customers from over 40 countries, Hybrigenics Services is internationally recognized. Among our services, our yeast two-hybrid screening technology, ULTImate Y2H, is extensively used in many research projects. The results obtained at Hybrigenics have been quoted in more than 480 scientific publications to date. Hybribody offers single-domain antibody selection and validation services. We handle the in vitro selection of antibodies against your protein from a fully synthetic humanized VHH library by an optimized Phage Display technology. VHHs have the advantages of being very small (15 kDa), affine and stable molecules. We validate the selected VHHs for in vitro and in vivo applications (ELISA, IF, Intrabody…). We can also fuse the VHH with Fc fragments from the species of your choice to deliver fully functional recombinant antibodies. In addition, Hybrigenics Services provides optimization of nanobodies coming from the Llama using yeast display technology. Nanobody® is a trademark of Ablynx.

Humana Biosciences

Prologue Biotech, 516 Rue Pierre et Marie Curie Labege, 31670 FranceHumana Biosciences is a preclinical Contract Research Organization specialized in Translational research in Digestive, Respiratory and Genito-Urinary therapeutic areas. The Company services include histological and immunohistochemical staining as well as RNA purification and PCR arrays on both normal controls and pathologically-confirmed human tissues (fresh, frozen or formalin-fixed, paraffin-embedded) obtained in full compliance with international Ethical Guidelines. Humana Biosciences also performs in vivo studies on small experimental animals, including transgenic mice, for the evaluation of the efficacy of drug candidates on validated experimental models for the pathologies of interest.

Humana Biosciences

Rue Pierre et Marie Curie Labège, Occitanie, 31670 FranceHumana Biosciences is a preclinical Contract Research Organization specialized in Translational research in Digestive, Respiratory and Genito-Urinary therapeutic areas. The Company services include histological and immunohistochemical staining as well as RNA purification and PCR arrays on both normal controls and pathologically-confirmed human tissues (fresh, frozen or formalin-fixed, paraffin-embedded) obtained in full compliance with international Ethical Guidelines. Humana Biosciences also performs in vivo studies on small experimental animals, including transgenic mice, for the evaluation of the efficacy of drug candidates on validated experimental models for the pathologies of interest.

Humana Biosciences

Rue Pierre et Marie Curie Labège, Occitanie, 31670 FranceHumana Biosciences is a preclinical Contract Research Organization specialized in Translational research in Digestive, Respiratory and Genito-Urinary therapeutic areas. The Company services include histological and immunohistochemical staining as well as RNA purification and PCR arrays on both normal controls and pathologically-confirmed human tissues (fresh, frozen or formalin-fixed, paraffin-embedded) obtained in full compliance with international Ethical Guidelines. Humana Biosciences also performs in vivo studies on small experimental animals, including transgenic mice, for the evaluation of the efficacy of drug candidates on validated experimental models for the pathologies of interest.

Helios BioSciences

102, avenue Gaston Roussel Romainville, 93230 FranceHelios BioSciences builds dynamic models mimicking the behavior of cell signaling cascades to accelerate the selection of reliable therapeutic targets or biomarkers.

Hopital Saint Antoine

184 Rue du Faubourg Saint Antoine 75571 Paris FranceHopital Saint Antoine focuses on clinical research areas.

Holodiag

Pharmaparc II -Voie de l'Innovation Val de Reuil, No entry required, 27100 FranceHolodiag is a customer-oriented Contract Research Organization dedicated to solid state and crystallization process of small molecules (APIs, intermediaites). We have been collaborating with fine chemical companies, biotechs and European laboratories since 2006 as a trusted partner for: - Analytical characterizations: XRPD, DSC, TGA, DVS, FTIR, PSD, IDR and more. - Solid state investigations: screenings (polymorphs, salts, co-crystals), stability/solubility/dissolution... - Crystallization conditions: development/optimization, product recovery, isomer separation, filtration, drying, robustness, trouble shooting... We can safely handle high toxicity samples with Occupational Exposure Levels of 50 ng/m3. We support our customers with the development of the right solid phases throughout the pharmaceutical development process, from pre-development to production. contact@holodiag.com

Holodiag

Pharmaparc II -Voie de l'Innovation Val de Reuil, No entry required, 27100 FranceHolodiag is a customer-oriented Contract Research Organization dedicated to solid state and crystallization process of small molecules (APIs, intermediaites). We have been collaborating with fine chemical companies, biotechs and European laboratories since 2006 as a trusted partner for: - Analytical characterizations: XRPD, DSC, TGA, DVS, FTIR, PSD, IDR and more. - Solid state investigations: screenings (polymorphs, salts, co-crystals), stability/solubility/dissolution... - Crystallization conditions: development/optimization, product recovery, isomer separation, filtration, drying, robustness, trouble shooting... We can safely handle high toxicity samples with Occupational Exposure Levels of 50 ng/m3. We support our customers with the development of the right solid phases throughout the pharmaceutical development process, from pre-development to production. contact@holodiag.com

Helioscience

Marseille, Provence-Alpes-Côte d'Azur FranceHelioscience offers in vitro and in vivo efficacy, photostability, mutagenicity, and phototoxicity testing services.

Imavita

3 rue des Satellites F-31400 Toulouse FranceImavita is an innovating technology company proposing preclinical services in the exploration of preclinical models of pathologies by the use of imaging techniques and analysis.

Institut Pasteur CITECH - Imagopole Core

28 Rue du Docteur Roux 75015, Paris France

Institut d'Expertise Clinique - IEC

88 Boulevard des Belges - 69006 Lyon - France"Setup in the 1990, IEC carries out safety and efficacy studies, in vitro tests, sensory analysis studies, and consumer tests for products of dermatological and ophtalmologic use in the cosmetic, pharmaceutical and chemical areas. The safety of your products and proof of their efficacy are the objectives we propose to undertake with you, to promote and highlight your creative capacities. Several yearly customer satisfaction survey amongst our customers, have enabled us to identify the strengths of IEC: ♦ quality and rigour ♦ fast execution ♦ respect of deadlines ♦ improvement and implementation of new technologies ♦ best value for money ♦ international opening We hope IEC will continue to answer to your expectations and reflect the image of an international service company."

Inserm Institut des Neurosciences de Montpellier (INM), Hôpital Saint Eloi

Hôpital Saint Eloi - Bâtiment INM 80, rue Augustin Fliche - BP 74103 Montpellier cedex 5, 34091 FranceThe Institute for Neurosciences of Montpellier (INM) concentrates basic research for studying transduction, integration and disorders of sensory and motor systems. The INM houses several teams working on vision, hearing, somatosensory wiring, and myelination. Molecular to systems level investigations are carried-out through core technical facilities at the INM. Our outputs favor the development of new treatments for sensory and motor deficits, with the strong interest on inherited retinal and optic blindness, auditory neuropathies (deafness and tinnitus), neurodegenerative diseases (amyotrophic lateral sclerosis, giant axonal neuropathy), sensitivity disorders (touch and pain) and glial pathologies (gliomas and Charcot Marie Tooth disease).

Institut Curie Reverse Phase Protein Array Facility

26 rue d’Ulm Cedex 05, Paris, 75248 FranceReverse Phase protein Arrays represent an innovative technology that allows studying protein expression levels and the activation status of cell signalling pathways. It combines high throughput analysis with minimal sample consumption. Using a dedicated arrayer, only 1 ng of proteins extracted from tissues or cell lines are printed onto nitrocellulose covered microscope slides (arrays). Proteins of interest are then quantified using highly specific primary antibodies. Up to one thousand samples can be analysed simultaneously on the same array. We systematically print serial dilutions and replicates for all samples, making the technology highly robust and quantitative. Our platform has validated almost 600 primary antibodies for RPPA labelling so far, among which almost 150 antibodies against phosphorylated proteins. This panel of antibodies covers the majority of cell signalling pathways. For each project, the project leader selects the antibodies of interest for his/her project among the validated antibodies. New antibodies are continuously being tested in the context of ongoing scientific projects.

Institut Curie Cytometry: Cell Sorting & Analysis Facility

26 rue d’Ulm Paris Cedex 05, 75248 FranceFlow cytometry measures the fluorescence or light diffraction of a large number of particles at high speed, such as cells, beads, bacteria, yeast, or organelles. At Institut Curie, flow cytometry is used mainly to quantify multiple markers on cells, with the option of simultaneously sorting multiple sub-populations of interest. The primary advantage of flow cytometry is how quickly it produces data for a very large number of cells, allowing for complex and/or rare sub-populations of cells to be analyzed and sorted so that they can then be cultured or analyzed with molecular biology tools. The cells in suspension may be simultaneously marked with 11 fluorochromes, each identifying a molecule of interest. The marked cells flow past a laser and, for each cell, the fluorescence intensity is quantified for each fluorochrome.
Fluorescent probes can be used to detect various parameters such as membrane potential, pH, or cell cycle (proliferation, apoptosis, etc). The flow cytometry platform performs cell sorting, and also trains people to independently use high-speed multiparameter cytometers and the supporting software to acquire and analyze data.

Institue de Biologie Structurale (IBS)

71 avenue des Martyrs CS 10090 Grenoble Cedex 9, 38044 FranceThe Institut de Biologie Structurale (IBS) is a research center for integrated structural biology funded by the CEA, the CNRS and the University Grenoble Alpes (Unite Mixte de Recherche, UMR 5075). The Institute performs interdisciplinary research at the interface of biology, physics and chemistry, and combines: • basic science • applied science and • technical innovation Our research themes, grouped around 3 research programs, are developed within eighteen groups. The IBS employs approximately 270 people. IBS scientists are active in training of undergraduate, master and PhD students and more than 20 Professors and Assistant Professors teach at the University Grenoble Alpes.

Institut de Recherches en Technologies et Science pour le Vivant (iRTSV)

17, rue des Martyrs CEA Grenoble Grenoble, 38054 France​L'Institut de Biosciences et Biotechnologies de Grenoble (BIG) développe des approches multidisciplinaires dans le but de décrypter les mécanismes moléculaires qui sont mis en jeu par les grands processus biologiques. Grâce aux plateformes de très haute technologie de l'institut et de son environnement, les architectures dynamiques qui composent le Vivant sont étudiées, de l'échelle atomique jusqu'à l'organisme entier. C'est grâce à la connaissance issue de cette approche multi-échelles que sont développés, avec nos partenaires académiques et industriels, de nouveaux dispositifs qui s'inspirent du Vivant. Les ruptures technologiques permises par cette approche bio-inspirée annoncent des retombées prometteuses qui participeront à l'amélioration de la santé et à un plus grand respect de notre environnement. ​

International Preclinical Services

La Grande Carrée 98, rue de Portillon F- 37540 Saint-Cyr-sur-Loire, FranceInternational Preclinical Services (IPSAR) provides toxicology and toxicopathology consulting.

Immunodiagnostic Systems (IDS)

153 avenue d’Italie, 75013 Paris, FranceImmunodiagnostic Systems (IDS) develops immunoassays and automated immunoanalyser technologies for use in clinical and research laboratories.

Institut Curie Bioinformatics Facility

26 rue d’Ulm Paris Cedex 05, 75248The Institut Curie Bioinformatics platform is composed of thirty bioinformaticians, biostatisticians and software engineers who offer a multidisciplinary expertise to support the biotechnological platforms, the research units and the hospital in their daily activities. Our skills range from statistical data analysis, data management, software development and high performance computing. We have five main missions: (1) knowledge and data integration, (2) collaborative support to biologists or clinicians for bioinformatics and biostatistics data analysis, (3) delivering advices and training in biostatistics and bioinformatics, (4) support to high performance computing and (5) coordination of bioinformatics activities within Institut Curie.

Institut Clinique de la Souris (ICS)

Illkirch, Grand Est FranceInstitut Clinique de la Souris (ICS) Mouse Clinical Institute specializes in translational research and functional genomics while offering genetic model validation, phenotypic analysis, and mouse model generation.

Integragen

1 rue de l'internationale, Evry, France 91000Integragen offers genomic and sequencing services.

IDEA TESTS Group

5, rue Jacques Monod - 33652 Martillac FranceSince 1999, IDEA is specialized in the evaluation of cosmetic products. IDEA's activities are split into 4 departments: clinical, in vitro, microbiology and regulatory advice. IDEA is based at 5 locations in Europe : 2 in Bordeaux, Brest, Annecy and Bucharest*. As an independent lab, IDEA is your guarantee that results are objectively obtained.

Institut Curie Protein Expression and Purification Core Facility

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe Protein Production and Purification Facility is a core service and resource to overcome the major bottleneck in recombinant protein expression and purification. Mainly we provide advice and active support for researchers scientific community in the use of the procaryotic and eukaryotic expression system for recombinant protein production. The facility offers equipment and materials required for the expression of protein in bacterial, Yeast, insect (baculovirus) and mammalian cell. We can execute the complete cloning, expression, scale-up and purification process or specific tasks within the project. We have optimized different expressions vectors in combination with various bacterial strains, yeast strain, insect strain and mammalian cell for specific expression of different types of proteins.

INOVALYS

Square Emile Roux 18 Boulevard de Lavoisier CS 20943 ANGERS cedex 01, 49009 Francebiological and chemical analysis in the areas of environment, food quality, animal and plant health for official organisms, industrialists, individuals

INOVALYS

128 Rue de Beaugé Le Mans, Pays de la Loire, 72000 Francebiological and chemical analysis in the areas of environment, food quality, animal and plant health for official organisms, industrialists, individuals

Innov'Orga

Innov'Orga Faculte des Sciences Moulin de la Housse Bat. 18 Chemin des Rouliers 51100 Reims FranceInnov'Orga offers custom synthesis, R&D services in organic chemistry and proposes a catalogue of innovative fluorinated building-blocks. Innov'Orga's team is highly qualified and has an expertise in fluorine organic chemistry.

Innov'Orga

chemin des rouliers, Faculte des sciences - Bat 18 France Reims, 51100 FranceInnov'Orga offers custom synthesis, R&D services in organic chemistry and proposes a catalogue of innovative fluorinated building-blocks. Innov'Orga's team is highly qualified and has an expertise in fluorine organic chemistry.

Inovarion

251 Rue Saint-Jacques Paris, Île-de-France, 75005 FranceAs part of its service delivery business, Inovarion develops and provides tailor-made services in life sciences: 1. Research expertise project missions 2. Missions of expertise in the pooling of technical services Furthermore, Inovarion has a recognized expertise in the field of biosensors.

INOVOTION

5 Avenue du Grand Sablon La Tronche, Auvergne-Rhône-Alpes, 38700 FranceINOVOTION is a biotech company which offers you a unique in vivo technology dedicated to oncology efficacy studies and early toxicity evaluations. Our Fast, Sensitive, Reliable and Affordable assay will save you time and money, to give you a clear competitive advantage. This breaking-thought technology, based on chick embryo, provides early analysis of your treatments before the classical preclinical stages. By eliminating low-value molecules early, INOVOTION accelerates your drug discovery process, increases your R&D productivity and reduces its costs. It’s rapid Go/No Go decision with multi-cancer screening capacities. This next generation of in vivo efficacy and toxicity tests covers fours main aspects: - EFFICACY assays for your anti-cancer treatments - EARLY TOXICITY assays for your drug candidates - TARGET VALIDATION in oncology - MULTI-CANCER SCREENING to (re)positioning your treatment We help chemists and biologists from companies and universities to validate a target and develop treatments by getting them through in vivo evaluation, while staying within their budget. These accessible efficacy and toxicity assays open really new perspectives of screening for wide variety of project researches.

INOVOTION

5 Avenue du Grand Sablon La Tronche, Auvergne-Rhône-Alpes, 38700 FranceINOVOTION is a biotech company which offers you a unique in vivo technology dedicated to oncology efficacy studies and early toxicity evaluations. Our Fast, Sensitive, Reliable and Affordable assay will save you time and money, to give you a clear competitive advantage. This breaking-thought technology, based on chick embryo, provides early analysis of your treatments before the classical preclinical stages. By eliminating low-value molecules early, INOVOTION accelerates your drug discovery process, increases your R&D productivity and reduces its costs. It’s rapid Go/No Go decision with multi-cancer screening capacities. This next generation of in vivo efficacy and toxicity tests covers fours main aspects: - EFFICACY assays for your anti-cancer treatments - EARLY TOXICITY assays for your drug candidates - TARGET VALIDATION in oncology - MULTI-CANCER SCREENING to (re)positioning your treatment We help chemists and biologists from companies and universities to validate a target and develop treatments by getting them through in vivo evaluation, while staying within their budget. These accessible efficacy and toxicity assays open really new perspectives of screening for wide variety of project researches.

INOVOTION

Biopolis, 5 Av du Grand Sablon France La Tronche, 38700 FranceINOVOTION is a biotech company which offers you a unique in vivo technology dedicated to oncology efficacy studies and early toxicity evaluations. Our Fast, Sensitive, Reliable and Affordable assay will save you time and money, to give you a clear competitive advantage. This breaking-thought technology, based on chick embryo, provides early analysis of your treatments before the classical preclinical stages. By eliminating low-value molecules early, INOVOTION accelerates your drug discovery process, increases your R&D productivity and reduces its costs. It’s rapid Go/No Go decision with multi-cancer screening capacities. This next generation of in vivo efficacy and toxicity tests covers fours main aspects: - EFFICACY assays for your anti-cancer treatments - EARLY TOXICITY assays for your drug candidates - TARGET VALIDATION in oncology - MULTI-CANCER SCREENING to (re)positioning your treatment We help chemists and biologists from companies and universities to validate a target and develop treatments by getting them through in vivo evaluation, while staying within their budget. These accessible efficacy and toxicity assays open really new perspectives of screening for wide variety of project researches.

Inventiva

50 rue de Dijon Daix, 21121 FranceInventiva has significant biology and chemistry expertise in nuclear receptor, transcription factor, epigenetics, and in therapeutic areas such as oncology, immuno-inflammation, fibrosis, cardiometabolic and neurodegenerative disorders

IntegraCell SAS

1 chemin du saulxier Bâtiment 4b Longjumeau, 91160 FranceThe IntegraCell platform carry out high quality functional metabolism exploration analyses of several central cell metabolisms, namely oxidative stress and mitochondria energy production, on your preferred biological model (cell, animal, …). It uses high throughput, muti-parametric, non-radioactive, quantitative readouts technology.

IntegraCell SAS

1 chemin du saulxier Bâtiment 4b Longjumeau, 91160 FranceThe IntegraCell platform carry out high quality functional metabolism exploration analyses of several central cell metabolisms, namely oxidative stress and mitochondria energy production, on your preferred biological model (cell, animal, …). It uses high throughput, muti-parametric, non-radioactive, quantitative readouts technology.

ImmunID Technologies

Cedex, FranceImmunID Technologies provides humanized mice for immuno-monitoring, immuno-profiling, and immuno-diagnostics.

Idenix

Montpellier, Cedex, FranceIdenix provides discovery and development of drugs for viral and infection diseases such as Hepatitis C and HIV.

Ipsogen

Marseille, Provence-Alpes-Côte d'Azur FranceIpsogen provides a diagnostic tests designed to map diseases, biomarker-based diagnostics for cancer, microarrays, and genomic profiling.

Institut Pasteur

28 Rue du Docteur Roux, Paris, Île-de-France 75015, FRThe Institut Pasteur was opened on November 14, 1888 thanks to Louis Pasteur’s international appeal for funds. He now had the facilities to extend vaccination against rabies, continue research on infectious diseases and share the resulting knowledge. The Institut Pasteur is a private, non-profit foundation. Its mission is to help prevent and treat diseases, mainly those of infectious origin, through research, teaching, and public health initiatives.

Institut Pasteur

25-28, rue du Docteur-Roux Paris Cedex 15, 75724 FranceThe Institut Pasteur was opened on November 14, 1888 thanks to Louis Pasteur’s international appeal for funds. He now had the facilities to extend vaccination against rabies, continue research on infectious diseases and share the resulting knowledge. The Institut Pasteur is a private, non-profit foundation. Its mission is to help prevent and treat diseases, mainly those of infectious origin, through research, teaching, and public health initiatives.

Institut Curie Flow Cytometry Facility

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe flow cytometry core facility of the Institut Curie in Orsay is available for Institut Curie research teams, external academic and to industry. Flow cytometry is generally used for a multiparametric analysis of individual cells in suspension, with the possibility of subsequently sorting subpopulations of interest. The cells in suspension may be simultaneously marked with many fluorochromes, each identifying a molecule of interest. The marked cells flow pass through a laser and, for each cell, the fluorescence intensity is quantified for each fluorochrome. Fluorescent probes can be used to detect different parameters such as: cell cycle, proliferation, apoptosis, pH changes and calcium flux. The purpose of the flow cytometry core facility is to sort cells for users, and to train facility users on the self-service cytometers and related software for data acquisition and analysis.

Institut de Biologie de L' Ecole Normale Superieure IBENS - Imaging Core

46, Rue d’Ulm 75005 Paris, France

Indicia Biotechnology

33, avenue de la Californie Oullins Oullins FranceIndicia Biotechnology provides immuno-diagnostics, microbiology, OEM production, microbiology, and sterile reagents.

Institut Curie In Vivo Experiments Facility

26 rue d’Ulm, Paris Cedex 05, 75248 FranceThe Institut Curie Research Center provides a spectrum of facility areas for housing a variety of different Vertebrate models, allowing the Institut Curie research community access to advanced technical expertise.

InvivoGen

Toulouse, FranceInvivoGen provides life scientists with innovative research reagents. As experts in innate immunity and cell culture, we offer a large selection of products including PRR ligands, cell lines, selective antibiotics, antimicrobial agents, vaccine adjuvants, and antibodies. Our TLR-expressing cell lines allow us to offer efficient TLR ligand screening.

InvivoGen

5 Rue Jean Rodier TOULOUSE, 31400 FranceInvivoGen provides life scientists with innovative research reagents. As experts in innate immunity and cell culture, we offer a large selection of products including PRR ligands, cell lines, selective antibiotics, antimicrobial agents, vaccine adjuvants, and antibodies. Our TLR-expressing cell lines allow us to offer efficient TLR ligand screening.

i3 Consult

3 Place de l’Eglise Liglet, Nouvelle-Aquitaine, 86290 Francei3 Consult is an information-based consulting, integration and IT outsourcing service entity committed to providing premium strategic marketing, financial and operational management solutions for healthcare, pharmaceutical and other life science organisations. For more information please check out our company video at: https://www.youtube.com/watch?v=gsg9jUzjQOs

Intestinal Biotech Development

FACULTE DE MEDECINE POLE RECHERCHE BD DU PROFESSEUR JULES LECLERC 59045 Lille Cedex FranceIntestinal Biotech Development provides leading-edge research services in digestive diseases. Our expertise includes all aspects of intestinal and hepatic inflammation, visceral pain, and metabolic issues. We are collaborating and partnering with an outstanding team of clinicians and a world-class academic research center dedicated to IBD. At the forefront of the industry, Intestinal Biotech Development has teamed with leading researchers, pharmaceutical companies, and food ingredient companies to bring fertile ideas into marketed medicines and food ingredients.

InsideBiotec consulting

Paris FranceInsideBiotec consulting is a French consulting firm specialized in supporting biotech companies in developing their business activities (including product and service-based offers) through marketing & communication services. Whether your company is at an early stage of its development (from project design in incubation to its first years of growth) or an already well-established structure, we can support you with marketing & communication services to answer your specific challenges.

Institut du Cerveau et de la Moelle Epiniere (ICM) Hopital Pitie Salpetriere

47 Boulevard de l'Hôpital Paris-13E-Arrondissement, Île-de-France, 75013 FranceThe Institut du Cerveau et de la Moelle épinière – ICM (Brain & Spine Institute) – is an international brain and spinal cord research center whose innovative concept and structure make it the only institute of its kind in the world. The ICM brings patients, doctors and researchers together with the aim of rapidly develop treatments for disorders of the nervous system and enable patients to benefit from them as quickly as possible. The best scientists from all backgrounds and countries come together at the Institute to perform leading-edge research in this area. To help researchers advance in their work and give patients tangible reasons for hope, we must all play a role: government agencies, corporate actors and individuals. No one can afford to idly stand by, because this fight is vital to every one of us.

INSERM Renal Fibrosis Lab

Rangueil University Hospital, Toulouse, FranceINSERM Renal Fibrosis Lab offers fibrosis models in addition to proteome and metabolome analysis services.

INSERM Renal Fibrosis Lab

Toulouse, Languedoc-Roussillon-Midi-Pyrénées FranceINSERM Renal Fibrosis Lab offers fibrosis models in addition to proteome and metabolome analysis services.

Institut Curie Department of Computational Systems Biology of Cancer

Paris, Île-de-France FranceComputational Systems Biology of Cancer group exists in the Bioinformatics Unit of Institut Curie since the end of 2004. Now it consists of several permanent researchers, postdocs and PhD students.

ICTA

11, Rue du Bocage Fontaine Les Dijon, 21121 FranceICTA (International Clinical Trials Association) offers support in clinical research and development including project management, clinical monitoring, data management, and biostatistics.

Institut Curie Experimental Radiotherapy

26 rue d’Ulm Paris Cedex 05, 75248 In the last few years, significant advances have been made in radiation therapy techniques (complex irradiation schemes, higher dose rates, new radiation types, wider range of indications etc.), but not all these advances have been validated in preclinical studies. The challenge lies in the complexity to apply these novel radiation treatments to cellular model or small animals. A platform providing support through interdisciplinary skills in experimental radiotherapy was therefore required, to improve the development of radiotherapy techniques.

Isochem

12 quai Henri IV 75194 Paris Cedex 04 FranceIsochem offers custom chemical synthesis and manufacturing services.

Institut Curie Therapeutic antibodies (TAB-IP) and Recombinant Antibodies

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe group uses its own fully synthetic phage display library of humanized llama recombinant single domain antibody that can provide high affinity binders without animal immunization. The library contains 3.109 independent nanobodies.

Industrade

17 RUE ALFRED KASTLER SCHILTIGHEIM, 67300 FranceTrade of industrial machines for the food industry and hygiene products for decontamination and cleaning

INVENesis

c/o INRAE, UMR, ISP, Batiment 311 Route de Crotelles Nouzilly, 37380 FranceINVENesis is a swiss biotechnology company based in Neuchâtel. We provide R&D services for drug discovery to industrial partners in the Animal Health, Plant Protection (Crop) and Pharmaceutical fields as well as Academia. We are an agile structure offering electrophysiology (on Xenopus oocytes and invertebrates) and organism-based (model organisms and parasitology) platforms to look for drugs, pheromones, bio-control and biologics with applications in parasitology, agriculture and human medicine. We provide the Science and the Technologies allowing you to screen chemical compounds and generate your own Intellectual Property. We offer a flexible business model where you pay for what you need.

Institut Curie Biomaging Cell and Tissue Core Facility (PICT-IBiSA)

26 rue d’Ulm Paris Cedex 05, 75248 FranceThe Biomaging Cell and Tissue Core Facility of the Institut Curie (PICT-IBiSA) gathers highly sophisticated equipments and up to date technologies in advanced microscopy. Its main aim is to provide research groups from inside and outside the Institut Curie with a workflow of state to the art imaging approaches to study at different scales and with complementary methods molecules, organelles, cells, whole organisms and tissues in normal and pathological states. Our Imaging Core Facility gathers equipment in advanced light microscopy (Optogenetics and Active Illumination setups, d-STORM, high resolution SIM, LLSM; multiple MP(NLO), Multi-Angle TIRFM…), electron microscopy (immunololabelling, cellular EM, High-pressure freezing, CryoEM, room temperature and cryo-EM tomography, STEM and EFTEM 2D/3D, chemical mapping) and NanoSIMS, and correlative light-electron microscopy.

Inserm

101 rue de Tolbiac Paris, 75654 FranceInstitut national de la santé et de la recherche médicale (Inserm) or National Institute of Health and Medical Research focuses on research in many areas of discipline.

Interchim

211 Bis avenue J.F. Kennedy - BP 1140 Montluçon, 03100 FranceInterchim manufactures and distributes consumables and instruments for research and industry.

Interchim

INTERCHIM Montluçon, Auvergne-Rhône-Alpes, 03100 FranceInterchim manufactures and distributes consumables and instruments for research and industry.

In Cell Art

1, Place Alexis Ricordeau Nantes Cedex 1 44093 FranceIn Cell Art provides gene synthesis, PCR, immunohistochemistry, microplate assays, microscopy, and fluorescence.

Innova Proteomics

263, avenue du Général Leclerc / Campus de Beaulieu BAT 24 Rennes, 35000 FranceInnova Proteomics provides high speed identification, biomarkers, peptide discovery, proteomics, and absolute quantification.

Institut Curie

26 rue d’Ulm Paris , 75248 FranceThe Institut Curie provides to researcher technological platforms for scientific imaging, genomics, proteomics and bioinformatics. Facilites improve diagnosis, treatment of cancer and follow-up of patients. Platforms include: * Chemical Library * Next Generation Sequencing * Synthetic Genetic Array (SGA) * Genomics * Mass Spectrometry and Proteomics Facility * Therapeutic Antobodies (TAB-IP) and Recombinant Antibodies * Protein Expression and Purification Core Facility * Reverse Phase Protein Array * "Cell & Tissue Imaging":/wares/make-a-request/quote_groups/new?name=Institut+Curie+-+Cell+and+Tissue+Imaging+Platform+%28PICT%29&provider=Institut+Curie+-+Cell+and+Tissue+Imaging+Platform+%28PICT%29 * Biophenics * Flow CYtometry * Cytometry: Cell Sorting & Analysis * Experimental Radiotherapy * In Vivo Experiments * Pre-clinical Investigation Laboratory (LIP) * Bioinformatics Platform

Institut Curie Biophenics Facility

26 rue d’Ulm Paris Cedex 05, 75248 FranceBioPhenics facility specializes in chemical biology as it relates drug discovery, biological probe discovery and phenotypic characterization of small-molecule effects (siRNAs and chemical compounds) on cellular systems. The facility provides basic and applied research teams with the technical resources and expertise needed to carry out high-content screens. The facility has enabled screening projects for different research groups in Europe, most of them located in cancer centers, aiming to benefit from the platform capabilities for identifying both the genes and pathways that mediate disease states and novel compounds that modulate these pathways. BioPhenics operates with a philosophy of collaboration, rather than fee-for-service. These screens can be carried out using small molecule or siRNA libraries curated by BioPhenics or with custom libraries developed by researchers.

Iris Pharma

ZI Les Nertières, Allée Hector Pintus F-06610 La Gaude FranceIris Pharma is a world-leading Contract Research Organization (CRO) offering preclinical and clinical ophthalmology research services. Iris Pharma works hand-in-hand with customers and has helped bring more than 70 ocular drugs and medical devices to international markets to date. The company is able to do this as efficiently as possible by maintaining a global view of the development process and by bringing personalized advice. Iris Pharma indeed addresses all ophthalmology challenges by offering programs and study designs that perfectly suit the needs of customers: therapeutic value assessment, full preclinical regulatory package, product value creation or à la carte studies. Compliance with GLP, ICH-GCP and GCLP requirements; CIR agreement.

Iris Pharma

Les Nertières Allée Hector Pintus La Gaude, 06610 FranceIris Pharma is a world-leading Contract Research Organization (CRO) offering preclinical and clinical ophthalmology research services. Iris Pharma works hand-in-hand with customers and has helped bring more than 70 ocular drugs and medical devices to international markets to date. The company is able to do this as efficiently as possible by maintaining a global view of the development process and by bringing personalized advice. Iris Pharma indeed addresses all ophthalmology challenges by offering programs and study designs that perfectly suit the needs of customers: therapeutic value assessment, full preclinical regulatory package, product value creation or à la carte studies. Compliance with GLP, ICH-GCP and GCLP requirements; CIR agreement.

Iris Pharma

Incubateur de l'Institut de la Vision, Bâtiment B1/B2 74 rue du Faubourg Saint Antoine Paris, 75012 FranceIris Pharma is a world-leading Contract Research Organization (CRO) offering preclinical and clinical ophthalmology research services. Iris Pharma works hand-in-hand with customers and has helped bring more than 70 ocular drugs and medical devices to international markets to date. The company is able to do this as efficiently as possible by maintaining a global view of the development process and by bringing personalized advice. Iris Pharma indeed addresses all ophthalmology challenges by offering programs and study designs that perfectly suit the needs of customers: therapeutic value assessment, full preclinical regulatory package, product value creation or à la carte studies. Compliance with GLP, ICH-GCP and GCLP requirements; CIR agreement.

INSIGHT BIOSOLUTIONS

Pépinière d'entreprises Biopôle 6 Rue Pierre Joseph Colin RENNES, 35000 FranceInsight Biosolutions (IBS) is a new startup company formed by expert team of Biologist, Clinician, Information technology and Commercial people. IBS team jointly have more than 20 years of working experience in Scientific innovation, biological materials & reagents manufacturing, commercialization of in-vitro models, in-vitro and in-silico services to Pharma and cosmetic industries.

INSIGHT BIOSOLUTIONS

Pépinière d'entreprises Biopôle 6 Rue Pierre Joseph Colin RENNES, RENNES, 35000 FranceInsight Biosolutions (IBS) is a new startup company formed by expert team of Biologist, Clinician, Information technology and Commercial people. IBS team jointly have more than 20 years of working experience in Scientific innovation, biological materials & reagents manufacturing, commercialization of in-vitro models, in-vitro and in-silico services to Pharma and cosmetic industries.

INSIGHT BIOSOLUTIONS

Pépinière d'entreprises Biopôle 6 Rue Pierre Joseph Colin RENNES, RENNES, 35000 FranceInsight Biosolutions (IBS) is a new startup company formed by expert team of Biologist, Clinician, Information technology and Commercial people. IBS team jointly have more than 20 years of working experience in Scientific innovation, biological materials & reagents manufacturing, commercialization of in-vitro models, in-vitro and in-silico services to Pharma and cosmetic industries.

ImaBiotech

152 Rue Dr Yersin Loos, 59320 FranceLocated in Europe (France) and North America (Billerica, MA), ImaBiotech offers End-to-end services from drug discovery to drug development. Using ImaLink platform, including unique imaging capabilities (GeoMx Nanostring, Mass Spectrometry Imaging, high multiplex IHC) and proprietary technologies (Multimaging™), ImaBiotech's experts can measure drug and biomarker distributions and concentrations at once, at single cell level within tissues. this allows to obtain the full picture of drug accumulation and impact to the tissue microenvironment. With the ImaLink platform, ImaBiotech offers a way to develop better and safer drugs from preclinical to clinical studies.

IODOLAB

1, avenue Bourgelat Marcy L'etoile, 69280 FranceIODOLAB specializes in biochemistry, performs trace element, mineral and vitamin analysis in several matrices (plasma, serum, urine, milk).

IODOLAB

Marcy-l'Étoile, Auvergne-Rhône-Alpes, 69280 FranceIODOLAB specializes in biochemistry, performs trace element, mineral and vitamin analysis in several matrices (plasma, serum, urine, milk).

IMSTAR

60 Rue Notre Dame-des-Champs Paris, 75006 FranceIMSTAR draws on its in-house expertise in biomodelling and statistics, cell biology and bioinformatics as wells on a network of experts in the fields of biology, cell biology, pathology, oncology, neurosciences, dermatopathology, cytogenetics, molecular genetics, and molecular medicine.

IMSTAR

Paris, Île-de-France FranceIMSTAR draws on its in-house expertise in biomodelling and statistics, cell biology and bioinformatics as wells on a network of experts in the fields of biology, cell biology, pathology, oncology, neurosciences, dermatopathology, cytogenetics, molecular genetics, and molecular medicine.

Institut François Magendie Animalerie

Préchac, Nouvelle-Aquitaine, 33730 France

Institut François Magendie Animalerie

Bordeaux, U862 France

Istem

Evry, FranceIstem provides screening, pathology models, therapeutic molecule development, genomics, stem cell services, and high throughput screening.

Institut Curie Pre-Clinical Investigation Laboratory (LIP) Facility

26 rue d’Ulm Paris Cedex 05, 75248 The treatment of cancer is continually improving due to increasing knowledge in oncogenesis and the development of new targeted compounds. Many candidate compounds for clinical trials are therefore generated each year.

Jamson PharmaChem

Plot No. A-713,Jamson PharmaChem offers API, intermediates, fine chemicals, and custom synthesis services.

JANVIER LABS

Route des Chênes Secs LE GENEST-SAINT-ISLE, 53940 FranceAs an international player of biomedical research, JANVIER LABS supplies experimental models with the highest standards to meet the needs of researchers. With the support of our teams of experts and our unique site in Europe – purpose built and designed at the forefront of innovation - entirely dedicated to rodent breeding, we guarantee strict breeding around 4 fundamental elements: highest standards for health quality, animal welfare, genetic stability, one sole microbiota. We offer a complete product and services portfolio to support rodent research models from creation to delivery. This includes a large range of research models (mice, rats, hamsters and gerbils) and dedicated support departments for model creation, customized breeding and the preparation of the models. Composed of scientists and veterinarians, our scientific support team supplies our users with rodent breeding expertise and knowledge of model characteristics. As a key player in Europe with more than 60 years experience, JANVIER LABS provides its models and services on the international stage with the same quality wherever our research partners are in the world. Our mission: to support research in order to improve tomorrow’s health

Korilog

4, rue Gustave Eiffel ZA Kervault-Est Questembert, 56230 FranceKorilog offers bioinformatics services.

Key-Obs

13 Avenue Buffon Orleans, 45100 FranceKey-Obs provides in vivo models and services related to the preclinical studies in central nervous system. Key-Obs proposes rodent models to examine the therapeutic efficacy of drugs for the treatment of psychiatric, neurologic and neurodevelopmental disorders such as attention deficit/hyperactivity disorder, depression, anxiety, obsessive-compulsive disorder, sleep disorders, stress, post-traumatic stress disorder (PTSD), drug abuse and dependence, alcoholism, schizophrenia, autism spectrum disorder, Parkinson disease, Huntington disease or others

Kynapse

28 Rue Jacques Ibert Levallois-Perret, 92300 France

Kayentis

4 route de la Noue
 91190 Gif-sur-Yvette – FranceKayentis offers a various range of software, medical solutions and services electronic patient reported outcome for facilitating your job in clinical data management.

Kallistem

Ecole Normale Supérieure de Lyon 46 allée d'Italie 69364 Lyon Cedex 07 FranceKallistem is a biotech company specialized in spermatogenesis. The company was founded in 2012 with the objective to anticipate and treat male infertility. It promotes a technology and expertise developed by Philippe Durand and Marie-Helene Perrard, two internationally renowned scientists in the field of the reproductive biology and more specially in in vitro spermatogenesis. Kallistem has developed, in collaboration with its partners, two original and innovating technologies of germinal cell culture for male fertility preservation and the treatment of male infertility.

Kallistem

VetAgro Sup - CRB aile 2 niveau 1 1, avenue Bourgelat Marcy l'Etoile, 69280 FranceKallistem is a biotech company specialized in spermatogenesis. The company was founded in 2012 with the objective to anticipate and treat male infertility. It promotes a technology and expertise developed by Philippe Durand and Marie-Helene Perrard, two internationally renowned scientists in the field of the reproductive biology and more specially in in vitro spermatogenesis. Kallistem has developed, in collaboration with its partners, two original and innovating technologies of germinal cell culture for male fertility preservation and the treatment of male infertility.

Kallistem

Ecole Normale Supérieure de Lyon 46 allée d'Italie Lyon Cedex 07, 69364 FranceKallistem is a biotech company specialized in spermatogenesis. The company was founded in 2012 with the objective to anticipate and treat male infertility. It promotes a technology and expertise developed by Philippe Durand and Marie-Helene Perrard, two internationally renowned scientists in the field of the reproductive biology and more specially in in vitro spermatogenesis. Kallistem has developed, in collaboration with its partners, two original and innovating technologies of germinal cell culture for male fertility preservation and the treatment of male infertility.

Keen Eye

74 rue du fauboug Saint-Antoine Paris, 75012 FranceKeen Eye is an AI platform company aiming at bringing decision-support and image analysis services for accelerating drug development from translational research to clinical phases and improving cancer diagnosis and therapies. Keen Eye brings accurate, standardized and undiscovered tissue insights through its cloud-based computational pathology platform which optimize users’ process and scale up their capacity.

Kokusan Chemical

8-29 2-chomeKokusan Chemical offers peptide synthesis and antibody preparation services in addition to supplying reagents.

KaironKem

20 rue Marc Donadille Technopôle de Chateau Gombert, Marseille 13013 FranceKaïronKem supplies various fine chemicals, screening libraries, and building blocks in addition to offering custom synthesis services.

Kimialys

4 rue Yvette Cauchois Gif-sur-Yvette, 91190 FranceKimialys offers ready-to-use gold biochips (SPR) and nanoparticles (LFA) coated with an innovative and patented surface chemistry, improving the sensitivity of sensors in any type of biological matrix.

Keyrus Biopharma

20 Rue Clément Bayard Levallois-Perret, Île-de-France, 92300 France

Léon Bérard Center

28 Rue Laennec 69008 Lyon, California, 04 78 78 28 28 United StatesThe Léon Bérard Center has three essential missions: care, research and teaching. The vocation of the center is to offer quality care to people suffering from cancer. This care that goes from screening to the most innovative treatments also takes into account the nutritional, psychological and rehabilitation aspects adapted to each individual.

Laboratoires Galéniques Vernin (LGV)

20 rue Louis-Charles Vernin 77190 Dammarie-Les-Lys FranceLaboratoires Galéniques Vernin specializes in manufacturing pharmaceutical and health industry products.

L'Oreal EpiSkin

41, Rue MartreL'Oreal EpiSkin develops and manufactures in vitro skin models for the application of efficacy and safety testing.

LABTOO

36 Avenue de Metz La Rochelle, 17000 FranceLabtoo is an outsourcing management company: we support and secure the R&D activities of our clients for their preclinical testing, clinical studies, and human biological samples searches. We are specialized in finding rare disease samples and difficult-to-find samples, such as genetic diseases, cystic fibrosis, infectious samples.

LibraGen

3 rue des satellites Bat. Canal Biotech. 31400 Toulouse FranceLibraGen provides biocatalysis, process development, industrial transfer and research services.

LibraGen

Toulouse, Occitanie FranceLibraGen provides biocatalysis, process development, industrial transfer and research services.

LHS Laboratoire

Carros, ItalyLHS Laboratoire specialize in private label manufacturing.

Legumes Centre Actions - LCA

Le Riou 41250 TOUR-EN-SOLOGNE

L2D Services

Cité InternationaleL2D Services provides consulting and operational management of services ranging from preclinical development to manufacturing.

L2D Services

Paris, Île-de-France FranceL2D Services provides consulting and operational management of services ranging from preclinical development to manufacturing.

LGC in partnership with ATCC

6 Rue Alfred Kastler BP 83076 Molsheim, Cedex, 67123 FranceATCC is a trusted and innovative global partner for high-quality authentic biomaterials, standards, and services. They are one of the world’s largest and most diverse resource centres providing human and animal cell lines, as well as molecular genomic tools, bacteria, viruses, protists, fungi, and biological reagents. LGC's partnership with ATCC facilitates the exclusive distribution of this extensive collection to Life Science researchers throughout Europe and Africa.

LXRepair

7 parvis Louis Néel BP 50 Grenoble, Cedex 9, 38040 FranceLXRepair is a CEA’s Spin off created in 2013 and expert in DNA Repair. We offer breakthrough enzymatic functional assays as an alternative to genomics to help Pharmas develop anticancer drugs and understand drugs mechanisms of action. LXRepair assays are currently used to stratify patients response to anticancer therapies in several clinical projects involving radiotherapy, chemotherapy and targeted therapies. We also explore DNA Repair as biomarker for response to checkpoint inhibitors. LXRepair plans to get the CE Mark certification for its first IVD kit to identify radiosensitive patients in 2024. LXRepair’s patented in vitro assays characterize DNA Damage Response and DNA Repair using a functional, multiplexed approach. Kits and service are available. We also offer service to cosmetic companies for aging and photoprotection studies. We look for Pharma/Biotech interested by the discovery of DNA Repair-based biomarkers in preclinical and clinical studies. We are also interested by diagnostic companies looking for partnership opportunities

LXRepair

BIOPOLIS 5 avenue du Grand Sablon La Tronche, 38700 FranceLXRepair is a CEA’s Spin off created in 2013 and expert in DNA Repair. We offer breakthrough enzymatic functional assays as an alternative to genomics to help Pharmas develop anticancer drugs and understand drugs mechanisms of action. LXRepair assays are currently used to stratify patients response to anticancer therapies in several clinical projects involving radiotherapy, chemotherapy and targeted therapies. We also explore DNA Repair as biomarker for response to checkpoint inhibitors. LXRepair plans to get the CE Mark certification for its first IVD kit to identify radiosensitive patients in 2024. LXRepair’s patented in vitro assays characterize DNA Damage Response and DNA Repair using a functional, multiplexed approach. Kits and service are available. We also offer service to cosmetic companies for aging and photoprotection studies. We look for Pharma/Biotech interested by the discovery of DNA Repair-based biomarkers in preclinical and clinical studies. We are also interested by diagnostic companies looking for partnership opportunities

Laboratoire M. Richard

Z.I Des REYS DE SAULCE Rue du Progrés 26270 SAULCE/RHÔNE FRANCELaboratoire M. Richard manufactures powders, granules, tablets, capsules, syrups, solutions for drinking and drops.

LABOCEA

7 bis rue du sabot Ploufragan, Bretagne, 22440 FrancePublic Veterinary Diagnostic Laboratory

LABOCEA

10 bis rue Claude Bourgelat Javené, Bretagne, 35133 FrancePublic Veterinary Diagnostic Laboratory

Life & Soft

CEA IDMIT 18 route du Panorama Fontenay-aux-roses, IDF, 92260 FranceLife and Soft is a bioinformatics company We offer bioinformatics and biostatistics services. We have a sequencing platform in France covering Illumina and Nanopore sequencing but also scRNA-seq. Our packaged offer in genomics covers DNA, microbiome, transcriptomics and methylation analysis. If you have sequencing data to analyze, our apps: Nanobiome, Onco Lifepipe and Nanoware Cloud hosted will give you a wide range of analysis (16S, Full 16S, Shotgun, targeted sequencing, ARTIC, COVIDseq...)

Life & Soft

VALLEE SUD BIO PARC 28 rue de la redoute Fontenay-aux-Roses, IDF, 92260 FranceLife and Soft is a bioinformatics company We offer bioinformatics and biostatistics services. We have a sequencing platform in France covering Illumina and Nanopore sequencing but also scRNA-seq. Our packaged offer in genomics covers DNA, microbiome, transcriptomics and methylation analysis. If you have sequencing data to analyze, our apps: Nanobiome, Onco Lifepipe and Nanoware Cloud hosted will give you a wide range of analysis (16S, Full 16S, Shotgun, targeted sequencing, ARTIC, COVIDseq...)

Lonza

Biopôle Clermont Limagne,Saint Beauzire, 63360 FranceLonza provides advanced cell biology and cell engineering solutions that support customers from discovery to the clinic. We provide primary human cells, specialized media, advanced cell culture and transfection tools, supported by best-in-class quality, regulatory and scientific support. We support customers from basic research through preclinical and process development stages of small molecules, biologics, and cell and gene therapy programs in drug discovery and immuno-oncology. This includes immunogenicity prediction and assessment, manufacturability risk assessment and protein re-engineering.

LNE - Laboratoire national de métrologie et d'essais

29 avenue Roger Hennequin Trappes , 78197 FranceA public industrial and commercial institution (EPIC designation), LNE has been placed under the trusteeship of the French Ministry for the Economy and Finance with oversight for Industry. Relying on an excellent scientific and technical skill set, LNE's research efforts have formed the basis of multiple applications: calibration, testing, certification, etc. Renowned for its expertise both in France and abroad, LNE performs measurements that serve the economy and society.

Laboratoire Cat

Lorris, Centre-Val de Loire, 45260 FranceLaboratoire Cat provides blister packaging, sterilization, and secondary packaging of drugs.

Laboratoires GILBERT

Avenue du général De Gaulle BP 115 14200 Hérouville Saint-Clair FranceLaboratoires GILBERT develops health products and cosmetics.

LESAFFRE INGREDIENTS SERVICES

67 rue de la Gare 50510 CERENCES France TVA FR 12 692 015 266Lesaffre Ingredients Services is a wholly-owned subsidiary of the Lesaffre group. We provide a range of services for processing food ingredients, including spray-drying, vacuum belt drying, granulation and microencapsulation. We act as service providers only and do not sell any of the ingredients that we handle.

Lynceus

61 rue du mont-cenis Paris, Idf, 75018 France

Laboratoires Chemineau

ZA l'Etang Vignon CS30003 37210 VOUVRAY FranceLaboratoires Chemineau specialize in the manufacture of aerosols, semi-liquid and liquid pharmaceutical products.

Laboratoires Codipharm

4, Rue de la PrayaLaboratoires Codipharm provides cosmetics, body care products, and cosmetic manufacturing.

Laboratoires Codipharm

Lège-Cap-Ferret, Aquitaine-Limousin-Poitou-Charentes FranceLaboratoires Codipharm provides cosmetics, body care products, and cosmetic manufacturing.

Latoxan

20, Rue Léon Blum Valence, 26000 FranceLatoxan supplies natural libraries of venoms and toxins from animal and plant origins.

Laboratoire BIO-EC

1 Chemin de Saulxier 91160 Longjumeau FranceCustom-made studies in claims substantiation for cosmetic and pharmaceutical companies. Created in 1998, BIO-EC is a research center dedicated to cosmetic and dermatological professionals. Our goal is to answer all kind of needs in claims substantiation. Several methods to assess products efficacy : animal-free efficacy testing for (dermo)cosmetics, clinical studies on volunteers, gene expression analysis, percutaneous absorption, RAMAN spectroscopy, topography.

Laboratoire BIO-EC

1 chemin de Saulxier Longjumeau, 91160 FranceCustom-made studies in claims substantiation for cosmetic and pharmaceutical companies. Created in 1998, BIO-EC is a research center dedicated to cosmetic and dermatological professionals. Our goal is to answer all kind of needs in claims substantiation. Several methods to assess products efficacy : animal-free efficacy testing for (dermo)cosmetics, clinical studies on volunteers, gene expression analysis, percutaneous absorption, RAMAN spectroscopy, topography.

LFB Group

3, avenue des TropiquesLFB Group provides therapeutic proteins, plasma-derived medicinal products, and biological drugs. LFB offers cell line development, preclinical process development, and clinical manufacturing services through its biomanufacturing division.

LFB Group

12 Avenue de Scandinavie Courtaboeuf Cedex, Île-de-France, 91967 FranceLFB Group provides therapeutic proteins, plasma-derived medicinal products, and biological drugs. LFB offers cell line development, preclinical process development, and clinical manufacturing services through its biomanufacturing division.

Minakem

145 chemin des LilasMinakem offers API, fine chemicals, custom synthesis, and manufacturing services.

MicroBioChips

Paris, Île-de-France FranceMicroBioChips provides protein array, biomarker, and screening services.

MyEnterix

Faculté de Médecine secteur Nord Boulevard Pierre Dramard Marseille, 13344 FranceMyEnterix is a biotechnology company that pioneered patch clamp recording on human enteric neurons

MyEnterix

Marseille, Provence-Alpes-Côte d'Azur FranceMyEnterix is a biotechnology company that pioneered patch clamp recording on human enteric neurons

MedinCell

Avenue de l’Europe Clapiers, 34830 FranceMedinCell is a clinical stage pharmaceutical company that develops a portfolio of long-acting injectable products in various therapeutic areas.

MedinCell

Clapiers, Occitanie FranceMedinCell is a clinical stage pharmaceutical company that develops a portfolio of long-acting injectable products in various therapeutic areas.

METAFORA biosystems

4 rue Pierre Fontaine 91058 Evry cedex FranceMETAFORA biosystems is a biotechnology company dedicated to developing the use of RBDs which are ligands of nutrient transporters.

METAFORA biosystems

4 rue Pierre Fontaine Evry cedex, 91058 FranceMETAFORA biosystems is a biotechnology company dedicated to developing the use of RBDs which are ligands of nutrient transporters.

Mitologics S.A.S

102 Avenue Gaston Roussel ROMAINVILLE , 93230 FranceMitologics S.A.S. is a biotechnology company specialized in detection of mitochondrial alterations. The company has developped technological platforms dedicated to compounds screening to identify compounds toxicity (DILI, cardio-toxicity) or efficacy (Oncology, Neuro-, Cardio-protection...). Among them, respiratory chain activity is measured in cultured cells or isolated mitochondria using Seahorse XFe-96 analyzer or soluble probes. Since 2009, Mitologics has performed more than 180 R&D studies for pharmaceutical companies and biotech, as well as cosmetic and agro-chemistry companies especially in Europe, the United States and Japan.

Mitologics S.A.S

Faculté de Médecine 8, rue du Général Sarrail Créteil, 94000 FranceMitologics S.A.S. is a biotechnology company specialized in detection of mitochondrial alterations. The company has developped technological platforms dedicated to compounds screening to identify compounds toxicity (DILI, cardio-toxicity) or efficacy (Oncology, Neuro-, Cardio-protection...). Among them, respiratory chain activity is measured in cultured cells or isolated mitochondria using Seahorse XFe-96 analyzer or soluble probes. Since 2009, Mitologics has performed more than 180 R&D studies for pharmaceutical companies and biotech, as well as cosmetic and agro-chemistry companies especially in Europe, the United States and Japan.

Med Discovery

Route de Pré-Bois 29 P.O. Box 527 1215 Genève 15 SwitzerlandMed Discovery provides clinical development for the treatment of cancer including uro-genital and oncology fields.

Medelpharm

43, Porte du Grand Lyon F-017100 Neyron, FranceMedelpharm provides tableting equipment, software, formulation, powder analysis and characterization.

Medelpharm

31, avenue Arsène d’Arsonval F-01000 Bourg en Bresse, FranceMedelpharm provides tableting equipment, software, formulation, powder analysis and characterization.

MACORS

Avenue 36-42 Marc Sangnier 92390 VILLENEUVE LA GARENNE FranceMACORS manufactures low dose products, bags and hormonal products.

Medicines for Malaria Venture (MMV)

PO Box 1826 20, rte de Pré-Bois 1215 Geneva 15, SwitzerlandMMV, a not-for-profit public-private partnership, was established as a foundation in Switzerland in 1999. Our mission is to reduce the burden of malaria in disease-endemic countries by discovering, developing and delivering new, effective and affordable antimalarial drugs. Our vision is a world in which these innovative medicines will cure and protect the vulnerable and under-served populations at risk of malaria, and help to ultimately eradicate this terrible disease.

M-Scan

12, Chemin des Aulx,SGS M-Scan offers mass spectrometry and chromatography services, including protein analysis, glycosylation analysis, antibody analysis, oligonucleotide analysis and bioanalysis.

mAbexperts

3 rue Henri Baigue Besançon, 21000 FrancemAbexperts, a team of 5 companies based on complementary expertise in the field of Antibody Engineering, with a large panel of custom services and products. RD-BIOTECH: High added value custom services in Immunology, Genetic and Cell Engineering: Development and biomanufacturing services: plasmid DNA, monoclonal antibodies, recombinant proteins and antibodies (Fab, bispecific, scFv…). Antiby engineering platform From DNA to recombinant antibodies development (antibody sequencing, reformatting, humanization, characterization...). Analytical platform for proteins characterization and its FastELISA kits range for Ig quantification and isotyping. DIACLONE: Centre of excellence in Monoclonal Antibody and Immunoassay development, with an extensive product portfolio of mAbs (catalog and bulk format - cytokins, cell adhesion markers, ...), ELISA and ELISpot kits (such as its murine and human IFN- ELISpot). Expertise in antibody development (hybridoma and phage display), immunoassay development, and bioassays services for antibody validation and characterisation (ELISA, cytometry, Octet...). SYNABS: A catalogue of anti-species secondary antibodies (anti-human, mouse, rat, bovine, rabbit,…) and an extensive expertise in the development of monoclonal antibodies in mice, as well as in rats (LOU rats) and guinea pigs using highly innovative technologies. QVQ: Recognized expertise in the phage display development of antibody fragments (VHH) from llamas. In addition to its services, offers a range of exclusive and high-quality VHHs. SMALTIS : offers tailor-made solutions with high added value, to fight against antibiotic resistance, to explore microbiota, and to optimize bioprocesses through bacterial strain engineering.

Medelis

15 rue Pierre BasseresMedelis provides clinical and preclinical management, medical monitoring, biostatistics, document preparation, model development, and animal models.

Merge Healthcare

22 Avenue Foch 54000 Nancy, FranceMerge Healthcare specializes in clinical systems and offers cloud-based solutions for imaging and data analytics.

MetaboHUB

Villenave-d'Ornon, Nouvelle-Aquitaine, 33140 FranceMetaboHUB is a national infrastructure of metabolomics and fluxomics that provides tools and services to academic research teams and industrial partners in the fields of health, nutrition, agriculture, environment and biotechnology.

MAbgène

Impasse des Chênes RougesMAbgène offers monoclonal antibodies, recombinant proteins from animal cell lines, expression, optimization, scale up and manufacturing services.

MAbgène

Alès, Occitanie FranceMAbgène offers monoclonal antibodies, recombinant proteins from animal cell lines, expression, optimization, scale up and manufacturing services.

Montpellier GenomiX

Rue de la Cardonille 34090 Montpellier, FranceMontpellier GenomiX provides sequencing services.

Mablink

69 rue de la République Espace Deskeo Lyon, 69002 FranceMablink Bioscience is a biotechnology company developing next-generation ADCs based on a proprietary PSARlink drug-linker platform technology and has a licensing activity to share this technology with Biotech or Pharma companies to help them to provide ADCs with improved physicochemical properties, pharmacokinetics, efficacy and tolerability for cancer patients.

Messenger Biopharma

22 rue Henri et Gilberte Goudier Riom, Auvergne-Rhône-Alpes, 63200 FranceMessenger Biopharma is a biotech company dedicated to research on messenger RNA (mRNA) design and in vivo delivery to human and animal tissues. Our patented Aegis biotechnology is about an uncapped mRNA that is 30 times cheaper to synthesize than any conventional capped mRNA. Furthermore, the transfection of our uncapped mRNA to mouse skin and skeletal muscle leads to reporter protein expression levels up to 10 times higher than those achieved with any classical capped mRNA. Messenger Biopharma is currently working on an innovation regarding the improvement of mRNA uptake in mouse tissues. We propose to sell you our proprietary mRNA coding your protein of interest to test and/or compare it with your current mRNA. We also wish to out-license our Aegis biotechnology to pharmaceutical companies, which develop mRNA-based drugs and vaccines.

Mellitech

17 rue des martyrsMellitech provides zinc imaging, beta cell biology, stable cell line generation, immuno-labeling, and insulin secretion measurement.

Merial Limited

29, avenue Tony Garnier 67007 Lyon FranceMerial is a world-leading animal health company. We are on the cutting edge of product development and innovation with a proven track record in producing pharmaceutical products and vaccines for pets, production animals, horses and wildlife.

Medit

2, rue du Belvédère, 91120 Palaiseau, FranceMedit provides CRO consulting, hit discovery, protein vaccine design, and drug design.

MAbSilico

1 impasse du Palais Tours, 37000 FranceMAbSilico is a deeptech company which implements computational solutions for antibody drug development. Based on AI and ML technologies, MAbSilico’s solutions are used to select, characterise and optimise antibodies to provide within 5 days qualified data (epitope, off-target, humanized sequences, new antibody designed) to our worldwide customers. MAbSilico's solutions accelerate and decrease the risks of faillure of antibody development programs.

MAbSilico

Domaine de l'Orfrasière Nouzilly, 37380 FranceMAbSilico is a deeptech company which implements computational solutions for antibody drug development. Based on AI and ML technologies, MAbSilico’s solutions are used to select, characterise and optimise antibodies to provide within 5 days qualified data (epitope, off-target, humanized sequences, new antibody designed) to our worldwide customers. MAbSilico's solutions accelerate and decrease the risks of faillure of antibody development programs.

Novalyst

BioParc, Blvd Brant, BP 30170, F-67405, Illkirch, FranceNovalyst provides organic synthesis, medicinal chemistry, drug design, and outsourcing services.

NatX-ray

Espace Porte du Gresivaudan 3 9 rue Marcel-Chabloz Saint Martin d'Hères, 38400 FranceNatX-ray offers crystallization screening, structure resolution, and in silico docking services.

NatX-ray

9 rue Marcel Chabloz Saint Martin d'Hères, 38400 FranceNatX-ray offers crystallization screening, structure resolution, and in silico docking services.

Nucleosyn

111, Bd Duhamel de MonceauNucleoSyn offers DNA and RNA monomers, amino acid building blocks and synthetic sphingolipids and phospholipids.

NCCR Frontiers in Genetics

Sciences III - University of GenevaNCCR Frontiers in Genetics offers genomics and bioimaging services.

NATEXPLORE SAS

25 Rue Lotissement la Chute des Eaux Prouilly Grand Est, 51140 FranceNatExplore is specialized in the chemical profiling of natural extracts

NAMSA

115 Chemin de l'Islon Chasse-sur-Rhône, Auvergne-Rhône-Alpes, 38670 FranceNAMSA is a Medical Research Organization (MRO), accelerating product development through integrated laboratory, clinical and consulting services. Driven by our regulatory expertise, NAMSA’s MRO® Approach plays an important role in translational research, applying a unique combination of disciplines—consulting, preclinical, toxicology, microbiology, chemistry, clinical and quality—to move client’s products through the development process, and continue to provide support through commercialization to post-market requirements, anywhere in the world.

Novotec

243, route de Sandrancourt F-78520 Saint Martin La Garenne, FranceNovotec provides ECM analysis, cell cultures, image analysis, culture supernatant dosages, and cellular viability.

Novotec

Saint-Martin-la-Garenne, Île-de-France FranceNovotec provides ECM analysis, cell cultures, image analysis, culture supernatant dosages, and cellular viability.

NewLab

23, Boulevard de L'EuropeNewLab provides oncology and animal management software.

Nexus Oncology

19 Rue Malesherbes Madeleine 75008 ParisNexus Oncology offers data management, site selection, project management, and drug development consultancy to support studies in oncology.

Neuroservice

LES JARDINS DE L'ENTREPRISE QUARTIER DE LA CONFRERIE LE PUY STE REPARADE, 13610 FranceNeuroservice is a private Contract Research Organization (CRO) providing pharmacological assays based on electrophysiological recordings of acute brain slices, spinal cord slices, neuronal cultures, human brain slices and iPSC-derived neurons. These assays are performed with two complementary techniques: Multi-Electrode Array (MEA) and Patch-Clamp. The mission of Neuroservice is to support the early phases of CNS and PAIN R&D programs in Lead Selection & Optimization as well as in the investigation of Mechanism of Action for pre-clinical compounds. Neuroservice is also able to perform electrophysiological recordings of slices from genetically engineered rodents and to address CNS Safety/Toxicology issues for any given compound.

Neuroservice

Pays d'Aix Techno Park Les Jardins de l'Entreprise LE PUY STE REPARADE, 13610 FranceNeuroservice is a private Contract Research Organization (CRO) providing pharmacological assays based on electrophysiological recordings of acute brain slices, spinal cord slices, neuronal cultures, human brain slices and iPSC-derived neurons. These assays are performed with two complementary techniques: Multi-Electrode Array (MEA) and Patch-Clamp. The mission of Neuroservice is to support the early phases of CNS and PAIN R&D programs in Lead Selection & Optimization as well as in the investigation of Mechanism of Action for pre-clinical compounds. Neuroservice is also able to perform electrophysiological recordings of slices from genetically engineered rodents and to address CNS Safety/Toxicology issues for any given compound.

Nuvisan

2400 Route Des Colles Biot, 06410 FranceNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

Nuvisan

2400 Route des Colles 2400, route des Colles Biot, Provence-Alpes-Côte d'Azur, 06410 FranceNUVISAN IN A NUTSHELL Introduction - NUVISAN is a fully integrated contract research organization "from the molecule to the patient" - With a track record of nearly four decades as one of the first German CROs (est. 1979) - Capabilities are distributed over five locations in Germany and France - Balanced client portfolio: pharmaceutical industry, biotech companies & academic institutions Staff - Headcount of 870 employees - 40% of the staff are academics and 38% of these with PhD level - High staff loyalty ensures business continuity during the project as also the opportunity build up reliable long-term relations Quality Metrics - >90% percent of our business is based on repeat business and reflects our clients Satisfaktion - High quality was multiple times confirmed by various authority inspections (e.g. BfArM, EMA, FDA, ANVISA) - 40 sponsor audits in 2019 SERVICE PORTFOLIO Drug Discovery R&D Services - Lead discovery & early development - Medicinal and computational chemistry - In vitro & in vivo pharmacology - DMPK & toxicology Analytical Labs - Nonclinical & clinical PK/TK analysis - Immunogenicity & biomarkers - Central lab services Non-Clinical Studies - DMPK in discovery & development - In vitro & in vivo PK studies - Isotope/radiolabeling Pharmaceutical Services - QP services - Clinical trial supply - Formulation support - Pharmaceutical testing Clinical Trials - In-house phase I/IIa - Multicenter trial management - Monitoring Complementary & Standalone Services - Consultancy - Data management - Data sciences - Medical writing - PK analysis

Noldus Information Technology

Paris, FranceNoldus Information Technology develops software and technology in the application of tracking animal behavior.

Noldus Information Technology

Nantes, FranceNoldus Information Technology develops software and technology in the application of tracking animal behavior.

NovAlix SAS

Campus de Maigremont. BP615 Val-de-Reuil, 27106 FranceNovAliX is a drug discovery-focused CRO with several unique technologies combining screening, chemistry, biophysics and structural biology. Services include: protein production, structure determination, custom synthesis, chemical process research, flow chemistry, medicinal chemistry, and numerous biophysical techniques for characterisation of protein -drug interactions: NMR, Native-MS, HDX-MS, SPR, ITC, MST, DLS, DSF. Structural techniques range from NMR, X-Ray Crystallography, Cryo-EM and MicroED.

Neuro-Sys

410 Chemin Departemental 60 Gardanne, 13120 FranceNeuro-Sys provides efficient and highly skilled preclinical modeling services. With a strong expertize and cutting-edge laboratory equipment, Neuro-Sys develops and uses specific preclinical models of CNS/PNS diseases (in vitro/in vivo) to achieve high-quality efficacy pharmacology and mode of action studies.

NMR tec

Bld. Sebastien Brandt Bioparc - Bat. B 67400 Illkirch, Graffenstaden, FranceNMRTEC provides solution and solid state NMR techniques, 33-D structure resolution, polymorphism assessment, API interactions, and structure/activity relationship.

NMR tec

Illkirch, Alsace-Champagne-Ardenne-Lorraine FranceNMRTEC provides solution and solid state NMR techniques, 33-D structure resolution, polymorphism assessment, API interactions, and structure/activity relationship.

Novasyn Organics

81 rue de Sevres, 92100, Boulogne-BillancourtNovasyn Organics specializes in multi-step synthesis of substituted pyridine compounds.

NOKAD

4 rue Pierre Fontaine, Evry 91000, FranceNOKAD provides functional knockout aniamls, functional characterization, mammalian adenoviral overexpression, and antibodies against low antigenic protein.

NOKAD

Évry, Île-de-France FranceNOKAD provides functional knockout aniamls, functional characterization, mammalian adenoviral overexpression, and antibodies against low antigenic protein.

NeuroAct Communication

25, rue des Généraux RicardNeuroAct Communication provides consulting for CNS drug discovery.

Novasep

Avenue du Lac 64150 Mourenx FRANCENovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Novasep

Rue Démocrite 72000 Le Mans FRANCENovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Novasep

Route de Givors 38670 Chasse-sur-Rhône FRANCENovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Novasep

Boulevard de la Moselle BP 50 - 54340 Pompey FRANCENovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Novasep

5 chemin du Pilon St Maurice de Beynost 01708 Miribel FRANCENovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Novasep

82, Boulevard de la MoselleNovasep provides chiral separations, custom synthesis, manufacturing, generics development, and purification scale-up.

Numoda

12/14 Rond Point des Champs Elysées, 75008 Paris, FranceNumoda offers support and consultation for companies moving from clinical development to marketing partners.

New Brunswick Scientific

60, route de SartrouvilleNew Brunswick Scientific offers optimization, cell expertise, computer-controlled strategies, and media formulation.

NSrepair

Institut de Neurosciences de la Timone, Campus Santé Timone 27 Bd Jean Moulin Marseille - Cedex 05, 13385 FranceNSrepair is a preclinical services company, highly specialized in acute neurological injuries

NanoAmor

OOCAP SAS, 5 AVENUE DE L’EUROPE ZA LA PILE 13760 SAINT-CANNAT FRANCE

Novocib

115, avenue Lacassagne 69003 Lyon, FranceBased on unique knowledge of nucleotide metabolism, NovoCIB provides analytic services for nucleotides profiling in cell extracts and innovative enzyme activity assay kits for Life Scientists and for Food R&D and Quality Control.

Novocib

Novocib sas 115 avenue Lacassagne Lyon, Auvergne-Rhône-Alpes, 69003 FranceBased on unique knowledge of nucleotide metabolism, NovoCIB provides analytic services for nucleotides profiling in cell extracts and innovative enzyme activity assay kits for Life Scientists and for Food R&D and Quality Control.

ONDAX Scientific S.I.

Calle Komentutxiki Kalea 28 , Hondarribia, , Gipuzkoa, 20280 SpainWho are we? ONDAX Scientific is an independent Contract Research Organisation (CRO) specialised in providing high quality Clinical Trial and Development services to the Pharmaceutical industry. Why choose ONDAX Scientific for your Clinical Trials? There are many reasons for choosing ONDAX Scientific, some of which include: A multidisciplinary, multilingual scientific team highly experienced in Clinical Trials and the Pharmaceutical Industry. A company structure that allows us to be totally flexible and highly responsive to individual client requirements. A working philosophy based on client focus, high quality standards and operating within agreed timelines. Our commitment We are totally committed to our projects: what's good for our clients is good for us. We only embark on a project if we have the human and technical resources to conduct and complete the project with guaranteed success. We commit to providing a professional, dedicated and high quality service to all our clients. Our references Since our creation in the year 2000, our portfolio of business clients has rapidly increased and today we collaborate with numerous companies in the pharmaceutical sector. Our clients range from large multinationals to small biotechnology companies with most of our clients choosing us as their Clinical Trial partners time and time again. This consistent high level of client satisfaction has made us one of the leading European specialists in Clinical Trials.

Oxeltis

1682 rue de la Valsière Montpellier, 34189 FranceOxeltis is a medicinal chemistry services company founded in Montpellier in 2010 by former researchers at Idenix Pharmaceuticals. The company has a small-scale custom synthesis business, as well as hit and lead optimization services, mainly in the areas of antivirals, antibiotics and anticancer compounds. The Oxeltis team comprises 16 experienced medicinal chemists (11 PhD, 5 MSc) with expertise in particular areas of organic synthesis: heterocyclic chemistry, macrocycles, nucleosides/nucleotides, modified sugars and oligo/polysaccharides. The team focuses on speed, quality and confidentiality in the services and collaborative ventures that it develops. Oxeltis works with European and North American start-up and big pharma companies as well as research institutions.

Oxeltis

1682 Rue de la Valsière Grabels, 34790 FranceOxeltis is a medicinal chemistry services company founded in Montpellier in 2010 by former researchers at Idenix Pharmaceuticals. The company has a small-scale custom synthesis business, as well as hit and lead optimization services, mainly in the areas of antivirals, antibiotics and anticancer compounds. The Oxeltis team comprises 16 experienced medicinal chemists (11 PhD, 5 MSc) with expertise in particular areas of organic synthesis: heterocyclic chemistry, macrocycles, nucleosides/nucleotides, modified sugars and oligo/polysaccharides. The team focuses on speed, quality and confidentiality in the services and collaborative ventures that it develops. Oxeltis works with European and North American start-up and big pharma companies as well as research institutions.

Oncodesign Biotechnology

18, route du Panorama BP 6 Fontenay-aux-Roses cedex, 92265 FranceSOLUTION PROVIDER ACROSS MAJOR THERAPEUTIC AREAS Oncodesign is a leading biopharmaceutical company that meets the needs of innovation in the health industry through precision medicine. The company has built an industrial model of innovation to orientate new therapeutic molecules to fight serious illnesses with unmet medical needs : cancer, immuno-oncology, immunology, inflammation and infectious diseases. Starting out from your targets or your molecules, we orient, drive and perform discovery or development programs to select the best drug candidates thanks to our following services: * IDDS (Integrated Drug Discovery Services) DRIVE --> From target validation to preclinical candidate and IND * DDSA (Discovery and Development Strategic Alliance) --> Strategic discovery program management up to clinical phase * Stand-alone services --> Proof of concept Pharmacology / Pharmaco imaging / Targeted radiotherapy / ADME DMPK / Bioanalysis/ Biopharmaceutical products services / Biodecontamination/Biosafety / Biobanking / WHAT CAN YOU EXPECT FROM ONCODESIGN? Oncodesign recognizes it is a significant investment for clients to select and access specialized technologies and expert scientist resources with extensive knowledge of pharmaceutical drug discovery and development. When it comes to outsourcing client projects, quality, innovation, time, and agility are key components for clients seeking to build a trusted and long-term relationship. * Helping our clients identify new approaches and anticipate tomorrow’s challenge Oncodesign is a vector for therapeutic innovation. As such, for over two decades, Oncodesign has invested in a continuum of technologies platforms (Predict®, Xmice®, T.O.T.®, OncoSNIPE® and Pharmimage®) to support Precision Medicine innovation model. These platforms come from the technological specificities of the company, thanks to a mesh pattern of scientific skills, knowledge & know-how and innovative technologies. Thanks to these platforms we support our clients investigating and establishing preclinical proof-of concept of a multitude of therapeutic approaches and products. So far, 5,000 advanced preclinical or clinical therapeutic solutions have been assess ranging from new chemical entities, biologics, cell or gene therapy, systemic targeted radiotherapies as well as combination therapies. * A strong track record Oncodesign’s multidisciplinary research teams and our seasoned management staff have had true accomplishments in drug discovery, having delivered more than 20 pre-clinical candidates to clients, partners and internally. A significant number of pre-clinical candidates, including first-in-class, have already progressed into clinical trials Besides, we have been serving more than 800 clients amongst pharmaceutical, biotech and life-science companies around the world to assess numerous treatment options in preclinical proof-of-concept studies across major therapeutic areas. We also take pride in the trust and fidelity of our clients proven by long term agreements and sustained repeat business. * Mutual understanding & customized project management We first listen to and understand clients’ requirements to design their tailored studies or discovery programs. Together, we set key milestones to reach endpoints such as activity, selectivity, pharmacological or ADME profile and toxicity, within a defined frame time. To allow our client to take informed and on-time decisions, we implement program or project management to insure constructive and regular discussions. * A collaborative mindset from a team with mix of backgrounds, experiences & skills For Oncodesign "we must succeed together". The creation of value arising from reciprocity, that is to say balanced, and transparent exchanges at all levels, with our partners, our clients. We acknowledge the diversity of our clients’ cultures and needs. However, all clients seek our team ability to design and perform studies or discovery programs encompass highest pharmaceutical standard to deliver robust data and products. Oncodesign combines a biotechnology mindset to seek for all fast track pathways along with a sense of service to deliver and communicate on purpose. Our management, scientific and business development teams encompass a mix of origin, experiences and skills. This diversity is a valuable asset to Oncodesign, allowing us to understand each unique client and to drive discovery programs knowing that no two projects will ever be the same. * Quality meeting client satisfaction & regulatory requirements Oncodesign’s quality management aims to set-up a framework to monitor our ability to meet client satisfaction in drug discovery and development along with regulatory requirements. We drive our quality management process in a continuous improvement approach, as part of the comprehensive company management. As such, Oncodesign welcomes inspections and audits from clients & health authorities for the work being considered. Furthermore, for non-clinical development, Oncodesign is GLP compliant with grade A certification from French authorities (ANSM). Oncodesign offers assessment solutions to evaluate innovative preventive and therapeutic strategies for COVID-19 (sars-CoV-2). Oncodesign’s mission is to discover innovative new therapies for serious diseases that do not currently have any known treatments. Operating within the framework of Infectious Disease Models and Innovative Therapies (IDMIT), Oncodesign is a major actor in the drug development ecosystem. Its in-house experience, acquired over 25 years, combined with working with other strategic partners, offers straightforward, immediately available or soon-to-be validated in vitro and in vivo models based on a broad number of readouts. This latest announcement means that clients will directly benefit from the most up-to-date scientific breakthroughs, enabling them to assess drugs for the benefit of COVID-19 patients.

Oncodesign Biotechnology

25-27 Avenue du Québec Villebon-sur-Yvette , 91140 FranceSOLUTION PROVIDER ACROSS MAJOR THERAPEUTIC AREAS Oncodesign is a leading biopharmaceutical company that meets the needs of innovation in the health industry through precision medicine. The company has built an industrial model of innovation to orientate new therapeutic molecules to fight serious illnesses with unmet medical needs : cancer, immuno-oncology, immunology, inflammation and infectious diseases. Starting out from your targets or your molecules, we orient, drive and perform discovery or development programs to select the best drug candidates thanks to our following services: * IDDS (Integrated Drug Discovery Services) DRIVE --> From target validation to preclinical candidate and IND * DDSA (Discovery and Development Strategic Alliance) --> Strategic discovery program management up to clinical phase * Stand-alone services --> Proof of concept Pharmacology / Pharmaco imaging / Targeted radiotherapy / ADME DMPK / Bioanalysis/ Biopharmaceutical products services / Biodecontamination/Biosafety / Biobanking / WHAT CAN YOU EXPECT FROM ONCODESIGN? Oncodesign recognizes it is a significant investment for clients to select and access specialized technologies and expert scientist resources with extensive knowledge of pharmaceutical drug discovery and development. When it comes to outsourcing client projects, quality, innovation, time, and agility are key components for clients seeking to build a trusted and long-term relationship. * Helping our clients identify new approaches and anticipate tomorrow’s challenge Oncodesign is a vector for therapeutic innovation. As such, for over two decades, Oncodesign has invested in a continuum of technologies platforms (Predict®, Xmice®, T.O.T.®, OncoSNIPE® and Pharmimage®) to support Precision Medicine innovation model. These platforms come from the technological specificities of the company, thanks to a mesh pattern of scientific skills, knowledge & know-how and innovative technologies. Thanks to these platforms we support our clients investigating and establishing preclinical proof-of concept of a multitude of therapeutic approaches and products. So far, 5,000 advanced preclinical or clinical therapeutic solutions have been assess ranging from new chemical entities, biologics, cell or gene therapy, systemic targeted radiotherapies as well as combination therapies. * A strong track record Oncodesign’s multidisciplinary research teams and our seasoned management staff have had true accomplishments in drug discovery, having delivered more than 20 pre-clinical candidates to clients, partners and internally. A significant number of pre-clinical candidates, including first-in-class, have already progressed into clinical trials Besides, we have been serving more than 800 clients amongst pharmaceutical, biotech and life-science companies around the world to assess numerous treatment options in preclinical proof-of-concept studies across major therapeutic areas. We also take pride in the trust and fidelity of our clients proven by long term agreements and sustained repeat business. * Mutual understanding & customized project management We first listen to and understand clients’ requirements to design their tailored studies or discovery programs. Together, we set key milestones to reach endpoints such as activity, selectivity, pharmacological or ADME profile and toxicity, within a defined frame time. To allow our client to take informed and on-time decisions, we implement program or project management to insure constructive and regular discussions. * A collaborative mindset from a team with mix of backgrounds, experiences & skills For Oncodesign "we must succeed together". The creation of value arising from reciprocity, that is to say balanced, and transparent exchanges at all levels, with our partners, our clients. We acknowledge the diversity of our clients’ cultures and needs. However, all clients seek our team ability to design and perform studies or discovery programs encompass highest pharmaceutical standard to deliver robust data and products. Oncodesign combines a biotechnology mindset to seek for all fast track pathways along with a sense of service to deliver and communicate on purpose. Our management, scientific and business development teams encompass a mix of origin, experiences and skills. This diversity is a valuable asset to Oncodesign, allowing us to understand each unique client and to drive discovery programs knowing that no two projects will ever be the same. * Quality meeting client satisfaction & regulatory requirements Oncodesign’s quality management aims to set-up a framework to monitor our ability to meet client satisfaction in drug discovery and development along with regulatory requirements. We drive our quality management process in a continuous improvement approach, as part of the comprehensive company management. As such, Oncodesign welcomes inspections and audits from clients & health authorities for the work being considered. Furthermore, for non-clinical development, Oncodesign is GLP compliant with grade A certification from French authorities (ANSM). Oncodesign offers assessment solutions to evaluate innovative preventive and therapeutic strategies for COVID-19 (sars-CoV-2). Oncodesign’s mission is to discover innovative new therapies for serious diseases that do not currently have any known treatments. Operating within the framework of Infectious Disease Models and Innovative Therapies (IDMIT), Oncodesign is a major actor in the drug development ecosystem. Its in-house experience, acquired over 25 years, combined with working with other strategic partners, offers straightforward, immediately available or soon-to-be validated in vitro and in vivo models based on a broad number of readouts. This latest announcement means that clients will directly benefit from the most up-to-date scientific breakthroughs, enabling them to assess drugs for the benefit of COVID-19 patients.

Oncodesign Biotechnology

20 rue Jean Mazen Dijon, 21076 Cedex FranceSOLUTION PROVIDER ACROSS MAJOR THERAPEUTIC AREAS Oncodesign is a leading biopharmaceutical company that meets the needs of innovation in the health industry through precision medicine. The company has built an industrial model of innovation to orientate new therapeutic molecules to fight serious illnesses with unmet medical needs : cancer, immuno-oncology, immunology, inflammation and infectious diseases. Starting out from your targets or your molecules, we orient, drive and perform discovery or development programs to select the best drug candidates thanks to our following services: * IDDS (Integrated Drug Discovery Services) DRIVE --> From target validation to preclinical candidate and IND * DDSA (Discovery and Development Strategic Alliance) --> Strategic discovery program management up to clinical phase * Stand-alone services --> Proof of concept Pharmacology / Pharmaco imaging / Targeted radiotherapy / ADME DMPK / Bioanalysis/ Biopharmaceutical products services / Biodecontamination/Biosafety / Biobanking / WHAT CAN YOU EXPECT FROM ONCODESIGN? Oncodesign recognizes it is a significant investment for clients to select and access specialized technologies and expert scientist resources with extensive knowledge of pharmaceutical drug discovery and development. When it comes to outsourcing client projects, quality, innovation, time, and agility are key components for clients seeking to build a trusted and long-term relationship. * Helping our clients identify new approaches and anticipate tomorrow’s challenge Oncodesign is a vector for therapeutic innovation. As such, for over two decades, Oncodesign has invested in a continuum of technologies platforms (Predict®, Xmice®, T.O.T.®, OncoSNIPE® and Pharmimage®) to support Precision Medicine innovation model. These platforms come from the technological specificities of the company, thanks to a mesh pattern of scientific skills, knowledge & know-how and innovative technologies. Thanks to these platforms we support our clients investigating and establishing preclinical proof-of concept of a multitude of therapeutic approaches and products. So far, 5,000 advanced preclinical or clinical therapeutic solutions have been assess ranging from new chemical entities, biologics, cell or gene therapy, systemic targeted radiotherapies as well as combination therapies. * A strong track record Oncodesign’s multidisciplinary research teams and our seasoned management staff have had true accomplishments in drug discovery, having delivered more than 20 pre-clinical candidates to clients, partners and internally. A significant number of pre-clinical candidates, including first-in-class, have already progressed into clinical trials Besides, we have been serving more than 800 clients amongst pharmaceutical, biotech and life-science companies around the world to assess numerous treatment options in preclinical proof-of-concept studies across major therapeutic areas. We also take pride in the trust and fidelity of our clients proven by long term agreements and sustained repeat business. * Mutual understanding & customized project management We first listen to and understand clients’ requirements to design their tailored studies or discovery programs. Together, we set key milestones to reach endpoints such as activity, selectivity, pharmacological or ADME profile and toxicity, within a defined frame time. To allow our client to take informed and on-time decisions, we implement program or project management to insure constructive and regular discussions. * A collaborative mindset from a team with mix of backgrounds, experiences & skills For Oncodesign "we must succeed together". The creation of value arising from reciprocity, that is to say balanced, and transparent exchanges at all levels, with our partners, our clients. We acknowledge the diversity of our clients’ cultures and needs. However, all clients seek our team ability to design and perform studies or discovery programs encompass highest pharmaceutical standard to deliver robust data and products. Oncodesign combines a biotechnology mindset to seek for all fast track pathways along with a sense of service to deliver and communicate on purpose. Our management, scientific and business development teams encompass a mix of origin, experiences and skills. This diversity is a valuable asset to Oncodesign, allowing us to understand each unique client and to drive discovery programs knowing that no two projects will ever be the same. * Quality meeting client satisfaction & regulatory requirements Oncodesign’s quality management aims to set-up a framework to monitor our ability to meet client satisfaction in drug discovery and development along with regulatory requirements. We drive our quality management process in a continuous improvement approach, as part of the comprehensive company management. As such, Oncodesign welcomes inspections and audits from clients & health authorities for the work being considered. Furthermore, for non-clinical development, Oncodesign is GLP compliant with grade A certification from French authorities (ANSM). Oncodesign offers assessment solutions to evaluate innovative preventive and therapeutic strategies for COVID-19 (sars-CoV-2). Oncodesign’s mission is to discover innovative new therapies for serious diseases that do not currently have any known treatments. Operating within the framework of Infectious Disease Models and Innovative Therapies (IDMIT), Oncodesign is a major actor in the drug development ecosystem. Its in-house experience, acquired over 25 years, combined with working with other strategic partners, offers straightforward, immediately available or soon-to-be validated in vitro and in vivo models based on a broad number of readouts. This latest announcement means that clients will directly benefit from the most up-to-date scientific breakthroughs, enabling them to assess drugs for the benefit of COVID-19 patients.

Oncodesign Biotechnology

20 rue Jean Mazen B.P. 27627 Dijon, 21076 Cedex FranceSOLUTION PROVIDER ACROSS MAJOR THERAPEUTIC AREAS Oncodesign is a leading biopharmaceutical company that meets the needs of innovation in the health industry through precision medicine. The company has built an industrial model of innovation to orientate new therapeutic molecules to fight serious illnesses with unmet medical needs : cancer, immuno-oncology, immunology, inflammation and infectious diseases. Starting out from your targets or your molecules, we orient, drive and perform discovery or development programs to select the best drug candidates thanks to our following services: * IDDS (Integrated Drug Discovery Services) DRIVE --> From target validation to preclinical candidate and IND * DDSA (Discovery and Development Strategic Alliance) --> Strategic discovery program management up to clinical phase * Stand-alone services --> Proof of concept Pharmacology / Pharmaco imaging / Targeted radiotherapy / ADME DMPK / Bioanalysis/ Biopharmaceutical products services / Biodecontamination/Biosafety / Biobanking / WHAT CAN YOU EXPECT FROM ONCODESIGN? Oncodesign recognizes it is a significant investment for clients to select and access specialized technologies and expert scientist resources with extensive knowledge of pharmaceutical drug discovery and development. When it comes to outsourcing client projects, quality, innovation, time, and agility are key components for clients seeking to build a trusted and long-term relationship. * Helping our clients identify new approaches and anticipate tomorrow’s challenge Oncodesign is a vector for therapeutic innovation. As such, for over two decades, Oncodesign has invested in a continuum of technologies platforms (Predict®, Xmice®, T.O.T.®, OncoSNIPE® and Pharmimage®) to support Precision Medicine innovation model. These platforms come from the technological specificities of the company, thanks to a mesh pattern of scientific skills, knowledge & know-how and innovative technologies. Thanks to these platforms we support our clients investigating and establishing preclinical proof-of concept of a multitude of therapeutic approaches and products. So far, 5,000 advanced preclinical or clinical therapeutic solutions have been assess ranging from new chemical entities, biologics, cell or gene therapy, systemic targeted radiotherapies as well as combination therapies. * A strong track record Oncodesign’s multidisciplinary research teams and our seasoned management staff have had true accomplishments in drug discovery, having delivered more than 20 pre-clinical candidates to clients, partners and internally. A significant number of pre-clinical candidates, including first-in-class, have already progressed into clinical trials Besides, we have been serving more than 800 clients amongst pharmaceutical, biotech and life-science companies around the world to assess numerous treatment options in preclinical proof-of-concept studies across major therapeutic areas. We also take pride in the trust and fidelity of our clients proven by long term agreements and sustained repeat business. * Mutual understanding & customized project management We first listen to and understand clients’ requirements to design their tailored studies or discovery programs. Together, we set key milestones to reach endpoints such as activity, selectivity, pharmacological or ADME profile and toxicity, within a defined frame time. To allow our client to take informed and on-time decisions, we implement program or project management to insure constructive and regular discussions. * A collaborative mindset from a team with mix of backgrounds, experiences & skills For Oncodesign "we must succeed together". The creation of value arising from reciprocity, that is to say balanced, and transparent exchanges at all levels, with our partners, our clients. We acknowledge the diversity of our clients’ cultures and needs. However, all clients seek our team ability to design and perform studies or discovery programs encompass highest pharmaceutical standard to deliver robust data and products. Oncodesign combines a biotechnology mindset to seek for all fast track pathways along with a sense of service to deliver and communicate on purpose. Our management, scientific and business development teams encompass a mix of origin, experiences and skills. This diversity is a valuable asset to Oncodesign, allowing us to understand each unique client and to drive discovery programs knowing that no two projects will ever be the same. * Quality meeting client satisfaction & regulatory requirements Oncodesign’s quality management aims to set-up a framework to monitor our ability to meet client satisfaction in drug discovery and development along with regulatory requirements. We drive our quality management process in a continuous improvement approach, as part of the comprehensive company management. As such, Oncodesign welcomes inspections and audits from clients & health authorities for the work being considered. Furthermore, for non-clinical development, Oncodesign is GLP compliant with grade A certification from French authorities (ANSM). Oncodesign offers assessment solutions to evaluate innovative preventive and therapeutic strategies for COVID-19 (sars-CoV-2). Oncodesign’s mission is to discover innovative new therapies for serious diseases that do not currently have any known treatments. Operating within the framework of Infectious Disease Models and Innovative Therapies (IDMIT), Oncodesign is a major actor in the drug development ecosystem. Its in-house experience, acquired over 25 years, combined with working with other strategic partners, offers straightforward, immediately available or soon-to-be validated in vitro and in vivo models based on a broad number of readouts. This latest announcement means that clients will directly benefit from the most up-to-date scientific breakthroughs, enabling them to assess drugs for the benefit of COVID-19 patients.

ORGA-LINK

Rond-Point de Gomberville PA Gomberville Magny-les-Hameaux, Île-de-France, 78114 FranceORGA-LINK is an independant CRO which proposes efficient services of Research and Development in Organic Synthesis on the scale from miligrams to kilograms. ORGA-LINK services also include extraction of natural products and analysis as well as the development of new compounds. ORGA-LINK proposes services in organic chemistry based on quality, flexibility and efficiency tailored to your needs with optimized costs. As multi-skilled chemists, we can realize every type of chemistry, from pharmaceuticals to peptide chemistry to inorganic chemistry with particularly strong expertise in the field of heterocyclic chemistry. TO KEEP YOUR TEAMS FOCUSED ON SUBJECTS OF HIGHER ADDED VALUE AND SAVE YOU BOTH TIME AND MONEY REDUCING YOUR COSTS OF SYNTHESIS : OUTSOURCE A PART OF YOUR R&D WORK. ORGA-LINK can meet your needs in term of : • Organic synthesis : multi-stage synthesis from the mg to multi-kg of derivatives, impurities, products, targets / leads and analogues • Classical or original synthesis: high pressure reaction, photosensitive (inactinic light), stable isotopic labelling (D, 13C, 15N) • R&D under contract in organic chemistry • Structural analysis, extraction • Quantitative analysis, dosage • Sourcing of compounds • Database and literature searching

ORGA-LINK

1 rue Amedee Gordini PA Gomberville Magny Les Hameaux, 78114 FranceORGA-LINK is an independant CRO which proposes efficient services of Research and Development in Organic Synthesis on the scale from miligrams to kilograms. ORGA-LINK services also include extraction of natural products and analysis as well as the development of new compounds. ORGA-LINK proposes services in organic chemistry based on quality, flexibility and efficiency tailored to your needs with optimized costs. As multi-skilled chemists, we can realize every type of chemistry, from pharmaceuticals to peptide chemistry to inorganic chemistry with particularly strong expertise in the field of heterocyclic chemistry. TO KEEP YOUR TEAMS FOCUSED ON SUBJECTS OF HIGHER ADDED VALUE AND SAVE YOU BOTH TIME AND MONEY REDUCING YOUR COSTS OF SYNTHESIS : OUTSOURCE A PART OF YOUR R&D WORK. ORGA-LINK can meet your needs in term of : • Organic synthesis : multi-stage synthesis from the mg to multi-kg of derivatives, impurities, products, targets / leads and analogues • Classical or original synthesis: high pressure reaction, photosensitive (inactinic light), stable isotopic labelling (D, 13C, 15N) • R&D under contract in organic chemistry • Structural analysis, extraction • Quantitative analysis, dosage • Sourcing of compounds • Database and literature searching

Osny Pharma

17, rue de Pontoise 95520 Osny - FranceOSNY Pharma offers integrated pharmaceutical services, from formulation to commercial manufacturing and packaging, focusing on highly-potent compounds.

Osny Pharma

Osny, Île-de-France, 95520 FranceOSNY Pharma offers integrated pharmaceutical services, from formulation to commercial manufacturing and packaging, focusing on highly-potent compounds.

OxiProteomics

2 rue Antoine Etex Créteil, 94000 FranceWe provide innovative solutions for efficacy testing of dermo-cosmetics in vitro, ex vivo et in vivo using targeted (in particular oxidative protein modifications) or un-targeted proteomics approaches. Our analytical pattform is also compatible with protein bioimarker analysis on any organ tissue or body fluid.

Oroxcell

102 avenue Gaston Roussel Romainville, 93230 FranceOroxcell is CRO and R&D partnership based in our company in the field of ADMET(Absorption Distribution Metabolism, Excretion, Toxicity) Efficacy and Bioanalysis. For many years Oroxcell has specialized in alternative methods to animal use and extensively invested in ADMET assays using promising 3D Human Organotypic models. Oroxcell's clients are pharmaceutical, dermato-cosmetic, nutrition health and medical device companies. Our laboratories are regularly inspected for GLP compliance.

PCAS

Route d’AvignonPCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

PCAS

19 route de Meulan, 78520 Limay, FrancePCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

PCAS

Route de Lassay, 61410 Couterne, FrancePCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

PCAS

15 avenue des frères-Lumière, 38300 Bourgoin-Jallieu, FrancePCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

PCAS

BP 181 - 23 Rue Bossuet, Z.I. La Vigne aux Loups, 91160 Longjumeau, FrancePCAS provides custom synthesis, intermediates, custom manufacturing, microelectrics, and protection additives.

Pierre Fabre Med. Plantes & Industrie

16 rue Jean Rostand, Gaillac, FrancePierre Fabre Med. Plantes & Industrie offers pharmaceutical ingredient development, chemistry manufacturing and controls, systems manufacturing, and process development.

Pierre Fabre Med. Plantes & Industrie

Gaillac, Occitanie, 81600 FrancePierre Fabre Med. Plantes & Industrie offers pharmaceutical ingredient development, chemistry manufacturing and controls, systems manufacturing, and process development.

Phytodia

Bioparc, Boulevard Sébastien Brant, BP30170, 67405 Illkirch, FrancePhytodia offers structural identification, mechanism determination, protocol development, and optimal dosing.

P.A.R.I.S.

21, quai du Clos des RosesP.A.R.I.S provides antibody solutions that perform to life science clients worldwide. Solutions for biopharmaceutical industry are development of mouse monoclonal antibodies, production of pre-clinical batches of antibodies, cross-reactivity studies of antibodies.

Provepharm Life Solutions

20 Rue Marc Donadille Marseille, Provence-Alpes-Côte d'Azur, 13013 FranceAt PROVEPHARM LIFE SOLUTIONS, we vitalize pharmaceutical and cosmetic research programs in small molecules and peptide chemistry. We add value to our clients’ preclinical and clinical projects at every step from process research through development to market. For all collaboration, our strength is to act as our clients’ labs. Small Molecules: Route scouting, custom synthesis, impurity isolation and characterization, process optimization for pilot scale, full package development prior to GMP production. > Heterocyclic chemistry, nucleosides, sugar chemistry, macrocycles Peptides: Drug product pre-formulation, supply of ready for use experimental batches, API GMP production, supply of finished product for clinical trials, one-stop shop. > Peptide-based vaccines, Multi-epitope polypeptide (one shot or ligation), MAP construction, Immuno-conjugated peptides (KLH, CRM) and folded, cyclic, stapled peptides.

Provepharm Life Solutions

22 Rue Marc Donadille Marseille, Provence-Alpes-Côte d'Azur, 13013 FranceAt PROVEPHARM LIFE SOLUTIONS, we vitalize pharmaceutical and cosmetic research programs in small molecules and peptide chemistry. We add value to our clients’ preclinical and clinical projects at every step from process research through development to market. For all collaboration, our strength is to act as our clients’ labs. Small Molecules: Route scouting, custom synthesis, impurity isolation and characterization, process optimization for pilot scale, full package development prior to GMP production. > Heterocyclic chemistry, nucleosides, sugar chemistry, macrocycles Peptides: Drug product pre-formulation, supply of ready for use experimental batches, API GMP production, supply of finished product for clinical trials, one-stop shop. > Peptide-based vaccines, Multi-epitope polypeptide (one shot or ligation), MAP construction, Immuno-conjugated peptides (KLH, CRM) and folded, cyclic, stapled peptides.

Provepharm Life Solutions

22 Rue Marc Donadille Marseille, Provence-Alpes-Côte d'Azur, 13013 FranceAt PROVEPHARM LIFE SOLUTIONS, we vitalize pharmaceutical and cosmetic research programs in small molecules and peptide chemistry. We add value to our clients’ preclinical and clinical projects at every step from process research through development to market. For all collaboration, our strength is to act as our clients’ labs. Small Molecules: Route scouting, custom synthesis, impurity isolation and characterization, process optimization for pilot scale, full package development prior to GMP production. > Heterocyclic chemistry, nucleosides, sugar chemistry, macrocycles Peptides: Drug product pre-formulation, supply of ready for use experimental batches, API GMP production, supply of finished product for clinical trials, one-stop shop. > Peptide-based vaccines, Multi-epitope polypeptide (one shot or ligation), MAP construction, Immuno-conjugated peptides (KLH, CRM) and folded, cyclic, stapled peptides.

Provepharm Life Solutions

PROVECUBE, 22 rue Marc Donadille France Marseille, 13013 FranceAt PROVEPHARM LIFE SOLUTIONS, we vitalize pharmaceutical and cosmetic research programs in small molecules and peptide chemistry. We add value to our clients’ preclinical and clinical projects at every step from process research through development to market. For all collaboration, our strength is to act as our clients’ labs. Small Molecules: Route scouting, custom synthesis, impurity isolation and characterization, process optimization for pilot scale, full package development prior to GMP production. > Heterocyclic chemistry, nucleosides, sugar chemistry, macrocycles Peptides: Drug product pre-formulation, supply of ready for use experimental batches, API GMP production, supply of finished product for clinical trials, one-stop shop. > Peptide-based vaccines, Multi-epitope polypeptide (one shot or ligation), MAP construction, Immuno-conjugated peptides (KLH, CRM) and folded, cyclic, stapled peptides.

Pharmaceutical Product Development (PPD)

27-35, rue Victor Hugo 94853 Ivry-sur-Seine Cedex FrancePPD offers central lab services, bioanalytical services, biomarker discovery services, assay development services, cGMP analytical services, CMC consulting, and pharmacology services.

Phylogene SA

62 RN 113 30620 Bernis FRANCEPhylogene SA is an R&D and servicing lab in genomics, transcriptomics, (PCR, rtPCR, NGS) proteomics, metabolomics (LC-MS/MS and immunotechniques) dedicated bioinformatics. These applications are mainly services to food, cosmetics and health industries including in vitro diagnostics, and environment industry.

Phylogene SA

62 Rte Nationale 113 Bernis, 30620 FrancePhylogene SA is an R&D and servicing lab in genomics, transcriptomics, (PCR, rtPCR, NGS) proteomics, metabolomics (LC-MS/MS and immunotechniques) dedicated bioinformatics. These applications are mainly services to food, cosmetics and health industries including in vitro diagnostics, and environment industry.

Pierre Fabre

Le Carla Burlats 81106 Castres Cedex - FRANCEPierre Fabre offers products based on therapeutic areas, dermo-cosmetics and family medication.

Phenotype Expertise

FrancePhenotype Expertise offers CNS and pain models for efficacy testing.

Progepi

1 rue Grandville Nancy, 54000 FrancePROGEPI - PROCESSlab is the centre for technology transfer of the LRGP (Reactions and Chemical Engineering Laboratory), located in ENSIC-Nancy. Since 2007, PROGEPI is integrated in the *ICEEL* institute (a national label given by ANR French Research National Agency) covering the Energy and Environment areas. Since its creation in 2005, PROGEPI has carried out about 600 studies for companies. We have a full-time team, an expertise of laboratories, as well as an access to their whole infrastructure (analytical equipment, test floors, documentation centre, computational equipment, mechanical workshop…).

ProtNeteomix

Nantes, Pays de la Loire FranceProtNeteomix offers array fabrication, molecular interaction detection, and protein production.

Pelvipharm

2 Avenue de la source de la bièvre UFR Sciences de la Santé MONTIGNY-LE-BRETONNEUX, Île-de-France, 78180 FrancePELVIPHARM is a contract research organization (CRO) delivering preclinical services in urology and genitourinary disorders, male and female sexual dysfunctions, cardiovascular / metabolism medicine, urology and women's health disorders using a unique platform of both in vivo experimental models and in vitro animal and human tissue-based specific research outsourcing services.

Physiogenex

280 RUE DE L'HERS ESCALQUENS, OCCITANIE, 31750 FrancePhysiogenex is a preclinical contract research organization (CRO) specializing in metabolic and cardiovascular diseases. We provide, first level phenotyping and screening, efficacy and proof-of-concept studies in metabolic diseases, diabetes, insulin resistance, obesity, dyslipidemia, cardiometabolic, kidney diseases, and liver diseases (NAFLD/NASH/liver fibrosis).

ProteoGenix

Espace Européen de l'Entreprise 19 rue de la Haye Schiltigheim, 67300 FranceProteoGenix is a leading life science organization which has been providing a unique access to 4 types of complementary custom services since 2003: Recombinant Protein Expression in 5 systems (E. coli, B. subtilis, Yeast P. pastoris and S. cerevisiae, Insect cells and Mammalian cells) Development of polyclonal and monoclonal antibodies guaranteed in many applications such as ELISA, sandwich ELISA, WB, FC, IF, IHC… Custom Peptide Synthesis Custom Gene Synthesis, Subcloning and Mutagenesis ProteoGenix’s commitment to its clients is to ensure the access to comprehensive and integrated solutions to help them develop the tools they need to efficiently conduct their biology and research projects in a time effective manner.

ProteoGenix

ProteoGenix SAS Espace Européen de l’Entreprise 15 rue de La Haye 67300 Schiltigheim, FranceProteoGenix is a leading life science organization which has been providing a unique access to 4 types of complementary custom services since 2003: Recombinant Protein Expression in 5 systems (E. coli, B. subtilis, Yeast P. pastoris and S. cerevisiae, Insect cells and Mammalian cells) Development of polyclonal and monoclonal antibodies guaranteed in many applications such as ELISA, sandwich ELISA, WB, FC, IF, IHC… Custom Peptide Synthesis Custom Gene Synthesis, Subcloning and Mutagenesis ProteoGenix’s commitment to its clients is to ensure the access to comprehensive and integrated solutions to help them develop the tools they need to efficiently conduct their biology and research projects in a time effective manner.

ProteoGenix

Espace Européen de l’Entreprise 15 rue de La Haye Schiltigheim, Alsace-Champagne-Ardenne-Lorraine, 67300 FranceProteoGenix is a leading life science organization which has been providing a unique access to 4 types of complementary custom services since 2003: Recombinant Protein Expression in 5 systems (E. coli, B. subtilis, Yeast P. pastoris and S. cerevisiae, Insect cells and Mammalian cells) Development of polyclonal and monoclonal antibodies guaranteed in many applications such as ELISA, sandwich ELISA, WB, FC, IF, IHC… Custom Peptide Synthesis Custom Gene Synthesis, Subcloning and Mutagenesis ProteoGenix’s commitment to its clients is to ensure the access to comprehensive and integrated solutions to help them develop the tools they need to efficiently conduct their biology and research projects in a time effective manner.

Pharmalex

50 Route de la Reine Boulogne-Billancourt, Île-de-France, 92100 FrancePharmaLex is a leading provider of specialized services for the pharma, biotech and medical device industries. We guide you from early strategic planning activities and non-clinical requirements through clinical development, regulatory submission processes and post-approval / maintenance post-launch activities. Our experts use technology-enabled solutions to support you through the entire product lifecycle. We deliver exceptional results — going above and beyond the standard to deliver tailor-made solutions worldwide.

PhysioStim

10 rue Henri Regnault Castres, Occitanie, 81100 FrancePhysioStim is a preclinical CRO that specializes in cardiovascular pharmacology & electrophysiology assays for drug development. PhysioStim offers models like ion channel studies, human cardiomyocytes studies, isolated perfused heart experiments, isolated organ bath studies, and MEA-Impedance studies.

PhysioStim

ZI DE BRENAS LAUTREC, NA, 81440 FrancePhysioStim is a preclinical CRO that specializes in cardiovascular pharmacology & electrophysiology assays for drug development. PhysioStim offers models like ion channel studies, human cardiomyocytes studies, isolated perfused heart experiments, isolated organ bath studies, and MEA-Impedance studies.

Platine Pharma Services

321 avenue Jean Jaurès Lyon, 69007 FrancePlatine Pharma Services offers immunomonitoring solutions including assays for cytotoxicity, proliferation, immunophenotyping, ligand binding, chemokines, cytokines, and anti-drug antibodies.

Physica Pharma

218-228, Avenue de Haut LévêquePhysica Pharma offers drug formulation development and delivery services.

Promo-Vert

Rue d'Aste Beon, BP 27 F- 64121 Serres Castet FranceSince its creation in 1985, PROMO-VERT S.A.S., is present on the CRO business through a network of 5 experimentation locations in France and is a leader on its market by offering the following services: · Open field trials for testing agrochemicals products, fertilizers, seed varieties. The results of these trials allow in fine to write down the BADs (Biological Assessment Dossier) to get the sales authorizations. These trials are set up according to the Good Experiment Practices for which PROMO-VERT S.A. has an agreement on behalf of the Ministry of Agriculture according to the new requirements of COFRAC, renewed in 2013. · Residue trials are designed to measure the residues of an agrochemical product after its application on the crop or in the soil. These trials are carried out according to the Good Laboratory Practices : PROMO-VERT S.A.S is agreed by the GIPC (Interministerial Grouping of Chemical products) in France renewed in 2013. PROMO-VERT S.A.S has also developed an European offer by creating a subsidiary in Spain in 1990 : PROMOVERT CROP Services (see web site down) which carries through the same type of services on the whole Spanish territory with the corresponding GEP or GLP Spanish certificates. On the other hand, through long-time co-workers, PROMO-VERT S.A.S coordinates the realization of European experimentation programs in Italy, Germany, Greece and United Kingdom.

PREDECT

126 blvd Pereire, 75017 Paris, FrancePREDECT is an IMI-funded partnership between 9 academic, 3 SME (Small and Medium Enterprise) and 7 EU pharmaceutical partners, aiming to develop novel, advanced, complex in vitro and in vivo models for breast, prostate and lung cancers.

Peritesco

18 avenue de l'Opéra 75001. Paris, FrancePeritesco offers occular toxicity, efficacy testing, and imaging services.

Peritesco

Paris, Île-de-France FrancePeritesco offers occular toxicity, efficacy testing, and imaging services.

PANPHARMA

Z.I du ClairayPANPHARMA offers contract manufacturing for powders for injection, liquids, and suspensions in addition to API supply/analysis services.

PathoQuest

11 Rue Watt, Paris-13E-Arrondissement, Île-de-France 75013, FRPathoQuest SAS, a spin off of Institut Pasteur, is a biotechnology company offering a game changing metagenomics approach to improving the breadth of pathogen detection. The company’s proprietary next generation sequencing (NGS) based testing approach delivers actionable reports to clinicians, biologists and biopharmaceutical quality assurance managers/production managers. PathoQuest’s proprietary sample preparation, and its comprehensive database of pathogens genomic information, enables clinicians and biopharma companies to overcome the current limitation of infectious agent detection. PathoQuest’s Viral Safety testing service, directed towards biopharmaceutical companies, is the company’s first commercial application of its testing approach and has quickly established a revenue stream for the company from several major biopharma companies.

PathoQuest

11 Rue Watt, Paris-13E-Arrondissement, Île-de-France 75013, FRPathoQuest SAS, a spin off of Institut Pasteur, is a biotechnology company offering a game changing metagenomics approach to improving the breadth of pathogen detection. The company’s proprietary next generation sequencing (NGS) based testing approach delivers actionable reports to clinicians, biologists and biopharmaceutical quality assurance managers/production managers. PathoQuest’s proprietary sample preparation, and its comprehensive database of pathogens genomic information, enables clinicians and biopharma companies to overcome the current limitation of infectious agent detection. PathoQuest’s Viral Safety testing service, directed towards biopharmaceutical companies, is the company’s first commercial application of its testing approach and has quickly established a revenue stream for the company from several major biopharma companies.

PathoQuest

11 Rue Watt, Paris-13E-Arrondissement, Île-de-France 75013, FRPathoQuest SAS, a spin off of Institut Pasteur, is a biotechnology company offering a game changing metagenomics approach to improving the breadth of pathogen detection. The company’s proprietary next generation sequencing (NGS) based testing approach delivers actionable reports to clinicians, biologists and biopharmaceutical quality assurance managers/production managers. PathoQuest’s proprietary sample preparation, and its comprehensive database of pathogens genomic information, enables clinicians and biopharma companies to overcome the current limitation of infectious agent detection. PathoQuest’s Viral Safety testing service, directed towards biopharmaceutical companies, is the company’s first commercial application of its testing approach and has quickly established a revenue stream for the company from several major biopharma companies.

PathoQuest

Pathoquest France Paris, 75, 75013 FrancePathoQuest SAS, a spin off of Institut Pasteur, is a biotechnology company offering a game changing metagenomics approach to improving the breadth of pathogen detection. The company’s proprietary next generation sequencing (NGS) based testing approach delivers actionable reports to clinicians, biologists and biopharmaceutical quality assurance managers/production managers. PathoQuest’s proprietary sample preparation, and its comprehensive database of pathogens genomic information, enables clinicians and biopharma companies to overcome the current limitation of infectious agent detection. PathoQuest’s Viral Safety testing service, directed towards biopharmaceutical companies, is the company’s first commercial application of its testing approach and has quickly established a revenue stream for the company from several major biopharma companies.

Protéus

Nimes, Occitanie FranceProtéus discovers, engineers, optimizes and produces new proteins and protein-based products and processes.

Promise Proteomics

7 parvis Louis Neel – BHT52A CS20050 38000 GRENOBLE – France France Grenoble, 38000 FrancePromise Advanced Proteomics was created in 2010 and is now a full subsidiary of the Aguettant group. Promise Proteomics is based in Grenoble, France. Promise Proteomics ethos is to develop innovative mass spectrometry-based technologies to address protein absolute quantification in biological samples. Promise protects its innovative developments by national and international patents and brands. These rights secure the exclusive marketing of our unique products and thus contribute to the economic success of our company. Our stable isotope labelled, and unlabelled full-length recombinant protein products are used by customers involved in these main application areas: Biomarkers evaluation and validation Pharmacokinetics studies of biotherapeutics Development of Certified Reference Materials Quantitation of therapeutic monoclonal antibodies in clinical research studies

POLARIS, NUTRITIONAL LIPIDS

5 chemin du Quilourin Moulin du Pont 29170 PLEUVEN – FrancePolaris has been an expert in the field of lipochemistry and is specialised in the production, development and formulation of polyunsaturated fatty acids, and marine-derived Omega-3 in particular.

Profilomic

31 rue d'Aguesseau 92100 Boulogne Billancourt FranceProfilomic is an innovative company offering a wide range of services in chemical, lipidomic and metabolomic analyses using liquid chromatography coupled to mass spectrometry ultra-high resolution (LC-FTMS). Through in-house and public databases, our software and our dedicated statistical analysis tools, we can meet all requests for biomarker discovery and characterization of small organic molecules in the health, environment and food areas. Profilomic has access to recent LC-MS instruments: LTQ-Orbitrap Discovery™, Q-Exactive™, Exactive™ (Thermo Scientific) and Maxis Q-TOF (Bruker).

Phycher

18 Chemin Lou TribailPhycher Bio Développement offers toxicology services including, acute toxicity, safety pharmacology, genotoxicity, and phototoxicity.

PX'Therapeutics

7, parvis Louis NéelPX'Therapeutics is a CDMO offering services for the development and production of recombinant proteins, monoclonal/polyclonal antibodies, antibody fragments and whole microorganisms. Founded in 2000, PX'Therapeutics can support your biological projects from DNA sequence optimization, screening of expression systems (microbial, yeast, mammalian), small scale production, process development up to GMP manufacturing.

PX'Therapeutics

7 Parvis Louis Néel - CS20050 - MINATEC BHT 52A Grenoble, 38040 FrancePX'Therapeutics is a CDMO offering services for the development and production of recombinant proteins, monoclonal/polyclonal antibodies, antibody fragments and whole microorganisms. Founded in 2000, PX'Therapeutics can support your biological projects from DNA sequence optimization, screening of expression systems (microbial, yeast, mammalian), small scale production, process development up to GMP manufacturing.

Popsi Cube

Le Campus 6 rue Jean Pierre Timbaud 78180 Montigny le Bretonneux Paris FrancePopsi Cube has a unique profile for an international Clinical Research Organisation providing distinctive and innovative dual expertise by combining clinical research implementation with the development of customized IT applications specific to the pharmaceutical industry, using agile method and digital iot for data capture optimization. Our expertise stems from many years of experience spent inside the largest CRO or pharmaceutical companies. We always considered IT as a valuable tool and as a way to improve and industrialize processes. It is our in-depth knowledge of pharmaceutical R&D which allows us to transform these tools to support a real advance in your clinical projects. Contact us to get started : +33 1 6 62 89 32 58

Popsi Cube

6 rue Jean-Pierre Timbaud Le Campus Bât A1 Sud Montigny-le-Bretonneux, Île-de-France, 78930 FrancePopsi Cube has a unique profile for an international Clinical Research Organisation providing distinctive and innovative dual expertise by combining clinical research implementation with the development of customized IT applications specific to the pharmaceutical industry, using agile method and digital iot for data capture optimization. Our expertise stems from many years of experience spent inside the largest CRO or pharmaceutical companies. We always considered IT as a valuable tool and as a way to improve and industrialize processes. It is our in-depth knowledge of pharmaceutical R&D which allows us to transform these tools to support a real advance in your clinical projects. Contact us to get started : +33 1 6 62 89 32 58

ProviSkin

18 rue Alain Savary 25000 Besançon ConnexionPROVISKIN propose des solutions innovantes destinées à la recherche en cosmétologie, dermatologie et toxicologie. La société a pour mission de renforcer l'efficience des tests de nos clients, principalement des laboratoires cosmétiques, pharmaceutiques et vétérinaires, en optimisant leurs processus de recherche sur explants de peau humaine et animale, tant congelée que fraiche. Pour répondre aux attentes de nos clients, la société Proviskin a développé une solution complète : une gamme de produits brevetés : Kit de peau K-Skin, cellule de diffusion D-Skin l’un des plus vastes réseaux de collecte de tissu humain en Europe, d’origine humaine et animale. une expertise d’études et de services dans le domaine cutané.

Phenocell

GrasseBiotech 45 Boulevard Marcel Pagnol Grasse, 06130 FrancePhenocell is a research-based biotechnology company specialized in the creation, production, and commercialization of cellular models and bioassays for the dermo-cosmetic and pharmaceutical industry through the Noble Prize-winnning technology of iPSC. We specialize in dermatology and ophthalmology, with specific bioassays for skin pigmentation, acne (hyper seborrhea), skin dryness (hypo seborrhea), CBD testing and inflammation, and for diseases that involve retinal degeneration. Phenocell is here to help you improve and accelerate your research and discovery programs with highly relevant in vitro tools.

Phenocell

4, rue Pierre Fontaine Evry cedex, F-91058 FrancePhenocell is a research-based biotechnology company specialized in the creation, production, and commercialization of cellular models and bioassays for the dermo-cosmetic and pharmaceutical industry through the Noble Prize-winnning technology of iPSC. We specialize in dermatology and ophthalmology, with specific bioassays for skin pigmentation, acne (hyper seborrhea), skin dryness (hypo seborrhea), CBD testing and inflammation, and for diseases that involve retinal degeneration. Phenocell is here to help you improve and accelerate your research and discovery programs with highly relevant in vitro tools.

Parexel

200 Rue Leonard de VinciParexel provides bioequivalence studies as well as clinical services across Phase I to Phase III of drug development including dose escalation, drug-drug interaction, biomarkers, first-in-man studies, ADME, imaging, and clinical research services.

Parexel

190 rue CHAMPIONNETParexel provides bioequivalence studies as well as clinical services across Phase I to Phase III of drug development including dose escalation, drug-drug interaction, biomarkers, first-in-man studies, ADME, imaging, and clinical research services.

Premier Research

Avenue des Sciences 11Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

Premier Research

29 rue TaitboutPremier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

Premier Research

1st floor, Rubra 2Premier Research, a midsize clinical research company, is dedicated to helping biotech, specialty pharma, and device innovators transform life-changing ideas and breakthrough science into new medical treatments. As a global company, Premier Research specializes in the use of innovative technologies for smart study design and trial management to deliver clean, conclusive data to sponsors. Whether it’s developing product lifecycle strategies, reducing clinical development cycle times, securing access to patients, navigating global regulations, maximizing the impact of limited rare disease data, or providing expertise in specific therapeutic areas, Premier Research is committed to helping its customers answer the unmet needs of patients across a broad range of medical conditions.

PKDERM SAS

45 Boulevard Pagnol Grasse Biotech Grasse, Choisir une province, 06130 FrancePKDERM is a French private company that provides smart innovative solutions for in vitro safety and efficacy testing. Created in 2018, PKDERM relies on the expertise of more than 20 years of its founder, Dr. Hanan Osman-Ponchet. As a former leader in metabolism and pharmacokinetics for large pharmaceutical companies, PKDERM’s CEO has developed and tested many alternatives to animal experiment models allowing a reliable and secure evolution from in-vivo experimentation to in-vitro experimentation. The company is located in Grasse, in the south of France and aims to support partners in the area of cosmetics/Personal care, dermatology, pharmaceutical, chemical, agro/petrochamical, and medical device industries. At PKDERM, we are familiar with an array of different assay systems to evaluate the safety and efficacy of new products. This allows us to work with our clients to determine the optimum assay that best fit their needs. Our acknowledged experience with our worldwide network of multidisciplinary partners enable us to rapidly support our customers confronted with new urgent testing needs. Our biological models include but not limited to: 2D culture of human skin cells (keratinocytes, fibroblasts, melanocytes), 3D human skin equivalent models, excised human skin, 2D and 3D human hepatocytes, 2D and 3D human lung models. Our in vitro safety testing includes but not limited to: dermal absorption, skin irritation, eye irritation, skin sensitization, cytotoxicity, phototoxicity, endocrine properties, metabolism, drug transporters and drug-drug interactions. Our in vitro pharmacology/efficacy testing includes but not limited to: dermal and nail absorption, anti-inflammatory properties, pigmentation, ageing, wound healing, ... We provide personalized service for every client and every project and we support the development of new products from the initial reflection and conceptualization to the data promotion and publication. We perform standard testing services as well as optimizing and validating new alternative assays. On the other hand, PKDERM offers scientific and project management services related to alternative methods to animal testing and provides workshops and practical training on the use of in vitro methods. Please do not hesitate to contact us if you need further assistance, have questions or need to place an order.

PKDERM SAS

28, Corniche Valmare Antibes, 06600 FrancePKDERM is a French private company that provides smart innovative solutions for in vitro safety and efficacy testing. Created in 2018, PKDERM relies on the expertise of more than 20 years of its founder, Dr. Hanan Osman-Ponchet. As a former leader in metabolism and pharmacokinetics for large pharmaceutical companies, PKDERM’s CEO has developed and tested many alternatives to animal experiment models allowing a reliable and secure evolution from in-vivo experimentation to in-vitro experimentation. The company is located in Grasse, in the south of France and aims to support partners in the area of cosmetics/Personal care, dermatology, pharmaceutical, chemical, agro/petrochamical, and medical device industries. At PKDERM, we are familiar with an array of different assay systems to evaluate the safety and efficacy of new products. This allows us to work with our clients to determine the optimum assay that best fit their needs. Our acknowledged experience with our worldwide network of multidisciplinary partners enable us to rapidly support our customers confronted with new urgent testing needs. Our biological models include but not limited to: 2D culture of human skin cells (keratinocytes, fibroblasts, melanocytes), 3D human skin equivalent models, excised human skin, 2D and 3D human hepatocytes, 2D and 3D human lung models. Our in vitro safety testing includes but not limited to: dermal absorption, skin irritation, eye irritation, skin sensitization, cytotoxicity, phototoxicity, endocrine properties, metabolism, drug transporters and drug-drug interactions. Our in vitro pharmacology/efficacy testing includes but not limited to: dermal and nail absorption, anti-inflammatory properties, pigmentation, ageing, wound healing, ... We provide personalized service for every client and every project and we support the development of new products from the initial reflection and conceptualization to the data promotion and publication. We perform standard testing services as well as optimizing and validating new alternative assays. On the other hand, PKDERM offers scientific and project management services related to alternative methods to animal testing and provides workshops and practical training on the use of in vitro methods. Please do not hesitate to contact us if you need further assistance, have questions or need to place an order.

Paris Flow Tech

24 Rue D'Ulm Paris, 75005 FranceChimie ParisTech - PSL provides an original and complete education, from bachelor’s to doctorate degrees, while conducting cutting-edge research covering the entire spectrum of chemistry. Ranked with PSL University at 36th place in the Shanghai 2020 ranking (ARWU), and 46th in the Times Higher Education 2021 World Rankings, the school trains engineers in chemistry who have a keen sense of innovation. Chimie ParisTech - PSL nurtures numerous industrial and academic partnerships, both nationally and internationally. In 2019, a flow chemistry platform ("Paris Flow tech") hosted within PSL by Chimie ParisTech-PSL, in partnership with ESPCI Paris-PSL and MINES ParisTech-PSL, has been launched with the aim to develop disruptive technologies within the heart of the Paris region by forming and organizing particularly innovative partnerships with companies in the fine chemicals/pharmaceuticals and formulation/cosmetology sectors.

Paris Flow Tech

24 Rue D'Ulm Paris, 75005 FranceChimie ParisTech - PSL provides an original and complete education, from bachelor’s to doctorate degrees, while conducting cutting-edge research covering the entire spectrum of chemistry. Ranked with PSL University at 36th place in the Shanghai 2020 ranking (ARWU), and 46th in the Times Higher Education 2021 World Rankings, the school trains engineers in chemistry who have a keen sense of innovation. Chimie ParisTech - PSL nurtures numerous industrial and academic partnerships, both nationally and internationally. In 2019, a flow chemistry platform ("Paris Flow tech") hosted within PSL by Chimie ParisTech-PSL, in partnership with ESPCI Paris-PSL and MINES ParisTech-PSL, has been launched with the aim to develop disruptive technologies within the heart of the Paris region by forming and organizing particularly innovative partnerships with companies in the fine chemicals/pharmaceuticals and formulation/cosmetology sectors.

Phoenix Pharmaceuticals

3 quai Kleber, Tour Sebastopol, 67000, Strasbourg, FrancePhoenix Pharmaceuticals Inc. specializes in Obesity, Cardiovascular, and Diabetes, providing over 7,000 peptide related products to researchers worldwide.

Phyliae Sarl

117 Route nationale 15 76190 Valliquerville France

Proteodynamics

Biopôle Clermont-Limagne Saint Beauzire, 63360 FranceProteodynamics specializes in protein and peptide characterization services including mass spectrometry, glycosylation analysis, sequencing, chromatography, and purification.

Proteodynamics

20 Rue Henri Goudier Riom, 63200 FranceProteodynamics specializes in protein and peptide characterization services including mass spectrometry, glycosylation analysis, sequencing, chromatography, and purification.

PRA Health Sciences

161 rue de CourcellesAt PRA Health Sciences, providing innovative solutions for our clients is what we do. But innovation just for the sake of innovation isn’t why we do it. Side-by-side with our clients, we strive to move drug discovery forward, to help them develop life-saving and life- improving drugs. We help change people’s lives for the better every single day. It’s who we are. Innovating to help people is at the heart of our process, but it’s even more than that. It’s also our privilege.

Prestagro

Zone Industrielle La Carie, Argentré 53210Expert in single or automated equipment dedicated to the food industry since 1994, our company is based in Mayenne, in Argentré next to Laval. Located at the crossroads of major food regions such as the Loire Valley, Brittany and Normandy, we operate throughout France and abroad.

QUALIPHYT

80 Chemin de Riboulin 26270 LORIOL SUR DROME (Drôme, France)

QUALIPHYT

80 Chemin de Riboulin Loriol-sur-Drôme, Auvergne-Rhône-Alpes, 26270 France

QuantaCell

2 allée du Doyen Georges Brus Pessac, 33370 FranceQuantaCell is a company specialized in data analysis and artificial intelligence for life sciences. It was founded in 2014 and now we are at the St Eloi Hospital in Montpellier (France). QuantaCell is at the heart of bio-medical questions and aware of clinical research units needs. Today, his team is able to provide powerful software solutions based on artificial intelligence and image analysis. QuantaCell quantifies customer’s data and images such as virtual slides, confocal/electron microscopy images, video and medical imaging for patients and small animals. QuantaCell analyses customer’s batches of images: -Cellular Analysis o Nuclear and cellular counting o Nucleic acid, proteins o Neuronal network detection o Viability o Cellular type segregation o Protein translocation o Kinetics (metastasis invasion) - Histological analyses H&E, IHC, immune-fluorescence, FISH, TMA, ... o Detection of cellular structures (for example Intestinal crypts, glomeruli, epidermis ...) o Specific organs analysis (eyes, hears) o Organ segmentation for small organism o Tumor detection, lesions o Angiogenesis and vascularization o Fibers detection (collagen, elastin) o Adipocyte … - Medical imaging o CT scan (for ex. Invasive nodule detection in chest), MRI, ultrasounds o Correlation with histological data o Organ segmentation o Image restoration - Statistics and bioinformatics o Statistical tests, data normalization, Multi-parametric study o Machine learning and deep learning algorithms (CNN, RNN, RCNN, YOLO, SSD, GAN) QuantaCell develops scientific applications for biomedical labs: scripts, desktop application, websites o Python, Matlab, R o C/C++, C# o Docker, JS, Databases, Flask, CSS o Automatic report generation (pdf, LaTeX) QuantaCell is flexible and offers consulting, technical studies and software development services

QuantaCell

QuantaCell, IRMB, Hopital St Eloi 80 av Augustin Fliche Montpellier CEDEX 5, Occitanie, 34295 FranceQuantaCell is a company specialized in data analysis and artificial intelligence for life sciences. It was founded in 2014 and now we are at the St Eloi Hospital in Montpellier (France). QuantaCell is at the heart of bio-medical questions and aware of clinical research units needs. Today, his team is able to provide powerful software solutions based on artificial intelligence and image analysis. QuantaCell quantifies customer’s data and images such as virtual slides, confocal/electron microscopy images, video and medical imaging for patients and small animals. QuantaCell analyses customer’s batches of images: -Cellular Analysis o Nuclear and cellular counting o Nucleic acid, proteins o Neuronal network detection o Viability o Cellular type segregation o Protein translocation o Kinetics (metastasis invasion) - Histological analyses H&E, IHC, immune-fluorescence, FISH, TMA, ... o Detection of cellular structures (for example Intestinal crypts, glomeruli, epidermis ...) o Specific organs analysis (eyes, hears) o Organ segmentation for small organism o Tumor detection, lesions o Angiogenesis and vascularization o Fibers detection (collagen, elastin) o Adipocyte … - Medical imaging o CT scan (for ex. Invasive nodule detection in chest), MRI, ultrasounds o Correlation with histological data o Organ segmentation o Image restoration - Statistics and bioinformatics o Statistical tests, data normalization, Multi-parametric study o Machine learning and deep learning algorithms (CNN, RNN, RCNN, YOLO, SSD, GAN) QuantaCell develops scientific applications for biomedical labs: scripts, desktop application, websites o Python, Matlab, R o C/C++, C# o Docker, JS, Databases, Flask, CSS o Automatic report generation (pdf, LaTeX) QuantaCell is flexible and offers consulting, technical studies and software development services

Quartz Bio

avenue de Sécheron 15 Switzerland Geneva, 1202 SwitzerlandQuartz Bio is a service company specialized in the computational analysis of biomarker data from clinical trials.

Quartz Bio

Avenue de Sécheron 15, Geneva, CH-1202 SwitzerlandQuartz Bio is a service company specialized in the computational analysis of biomarker data from clinical trials.

Q-Pharm

Level 6, Block 8Q-Pharm offers phase I clinical research services including bioanalysis, assay development/validation, pharmacokinetic analysis, data analysis, PK analysis, and bioequivalence.

Quipment SAS

132 Rue Andre Bisiaux Maxeville, 54320 FranceWhen renting medical devices at Quipment TM, you not only get your investigator sites equipped on time. You also get leading-edge tools to pilot your study equipment like never before. Quipment is setting new standards in equipment rental and management. With Quipsite®, the most integrated platform on the market, Quipment brings a unique technology that allows its customers to deploy and manage study equipment with unparalleled efficiency.

Quinten

8, RUE VERNIER 75017 PARIS FRANCEQuinten is a pioneer in data science and the strategic application of data in business.

Quinten

8 Rue Vernier Paris, Île-de-France, 75017 FranceQuinten is a pioneer in data science and the strategic application of data in business.

Qima Life Sciences

Prologue Biotech 516 rue Pierre et Marie Curie Labège, 31670 FranceQIMA Life Sciences (previously Bioalternatives and Synelvia) is a Contract Research Organization (CRO) established in 1996 and specializing in cellular and molecular pharmacology. We offer assays ranging from in silico screening to non-invasive clinical sample bioanalysis, as well as in vitro and ex vivo assays. QIMA Life Sciences contributes to the development of in vitro methods as an alternative to animal experimentation, by offering solutions dedicated to preclinical research and to the development of drug candidates and to cosmetic active ingredients and formulations. Beyond this activity of product evaluation and development and thanks to our offer of customized competitive services based on collaborative innovation, QIMA Life Sciences can assist the health industry with its new strategic choices. Our assays are performed on our two French sites, in Gençay (Vienne) and Labège (Haute-Garonne). With 60 experts and two 1000 square meter laboratories, our firm helps the marketing and R&D departments of big European and American cosmetic and pharmaceutical groups to innovate in the field of project conceptualization and to substantiate and support their product claims.

Qima Life Sciences

1bis Rue des Plantes Gencay, Vienne, 86160 FranceQIMA Life Sciences (previously Bioalternatives and Synelvia) is a Contract Research Organization (CRO) established in 1996 and specializing in cellular and molecular pharmacology. We offer assays ranging from in silico screening to non-invasive clinical sample bioanalysis, as well as in vitro and ex vivo assays. QIMA Life Sciences contributes to the development of in vitro methods as an alternative to animal experimentation, by offering solutions dedicated to preclinical research and to the development of drug candidates and to cosmetic active ingredients and formulations. Beyond this activity of product evaluation and development and thanks to our offer of customized competitive services based on collaborative innovation, QIMA Life Sciences can assist the health industry with its new strategic choices. Our assays are performed on our two French sites, in Gençay (Vienne) and Labège (Haute-Garonne). With 60 experts and two 1000 square meter laboratories, our firm helps the marketing and R&D departments of big European and American cosmetic and pharmaceutical groups to innovate in the field of project conceptualization and to substantiate and support their product claims.

Qima Life Sciences

Gençay, Aquitaine-Limousin-Poitou-Charentes, 86160 FranceQIMA Life Sciences (previously Bioalternatives and Synelvia) is a Contract Research Organization (CRO) established in 1996 and specializing in cellular and molecular pharmacology. We offer assays ranging from in silico screening to non-invasive clinical sample bioanalysis, as well as in vitro and ex vivo assays. QIMA Life Sciences contributes to the development of in vitro methods as an alternative to animal experimentation, by offering solutions dedicated to preclinical research and to the development of drug candidates and to cosmetic active ingredients and formulations. Beyond this activity of product evaluation and development and thanks to our offer of customized competitive services based on collaborative innovation, QIMA Life Sciences can assist the health industry with its new strategic choices. Our assays are performed on our two French sites, in Gençay (Vienne) and Labège (Haute-Garonne). With 60 experts and two 1000 square meter laboratories, our firm helps the marketing and R&D departments of big European and American cosmetic and pharmaceutical groups to innovate in the field of project conceptualization and to substantiate and support their product claims.

Qima Life Sciences

1 bis rue des plantes F-86160 Gencay FranceQIMA Life Sciences (previously Bioalternatives and Synelvia) is a Contract Research Organization (CRO) established in 1996 and specializing in cellular and molecular pharmacology. We offer assays ranging from in silico screening to non-invasive clinical sample bioanalysis, as well as in vitro and ex vivo assays. QIMA Life Sciences contributes to the development of in vitro methods as an alternative to animal experimentation, by offering solutions dedicated to preclinical research and to the development of drug candidates and to cosmetic active ingredients and formulations. Beyond this activity of product evaluation and development and thanks to our offer of customized competitive services based on collaborative innovation, QIMA Life Sciences can assist the health industry with its new strategic choices. Our assays are performed on our two French sites, in Gençay (Vienne) and Labège (Haute-Garonne). With 60 experts and two 1000 square meter laboratories, our firm helps the marketing and R&D departments of big European and American cosmetic and pharmaceutical groups to innovate in the field of project conceptualization and to substantiate and support their product claims.

Rovaltain Research Company

1 Avenue de la gare, 26300 Alixan, FranceFormed in April 2014 Rovaltain Research Company is a newly established private contract research organisation providing expert services for ecotoxicology and environmental toxicology. Our company philosophy is to provide in all its activities and communications: Scientific excellence Quality and timeliness of result Cost effectiveness We pride ourselves in being able to offer a new and exciting innovative service within the realms of ecotoxicology and environmental toxicology to both our academic and industrial clients.

Roowin

102, Avenue Gaston RousselRoowin offers API synthesis, custom compound synthesis, and cheminformatic services.

RD-Biotech

3, Rue Henri Baigue 25000 Besançon, FRANCEA French company founded in 2002, RD-Biotech has a complete technical platform and a high-level scientific expertise in molecular biology, recombinant proteins, antibody and cellular engineering. Customized services tailored to the needs of R & D, preclinical and clinical projects: Bioproduction and purification: Plasmids (up to grams), monoclonal antibodies (up to several grams) recombinant antibodies and recombinant proteins (several expression systems: CHO, HEK cells, E;coli, in vitro system...), cells - Standard quality, endofree or high grade quality (GMP Like) Development of expression vectors, gene design, cell lines and stable pools, murine hybridomas Recombinant antibodies: Antibody Sequencing, Chimerization and Humanization, characterization and validation (specificity, affinity, bioactivity) Analytical platform: ELISA, Blotting, Cytometry, OCTET, PCR and qPCR ...: development of methods, validation of procedures, analysis and quality control A range of FastELISA kits for the quantification of human, mouse, rat, and contaminant Ig (bovine Ig, protein A, etc.). Antibodies anti rabies for ELISA applications RD-Biotech is a company of the mAbexperts group (www.mabexperts.com)

RD-Biotech

18 rue Françoise Dolto Besançon, 25000 FranceA French company founded in 2002, RD-Biotech has a complete technical platform and a high-level scientific expertise in molecular biology, recombinant proteins, antibody and cellular engineering. Customized services tailored to the needs of R & D, preclinical and clinical projects: Bioproduction and purification: Plasmids (up to grams), monoclonal antibodies (up to several grams) recombinant antibodies and recombinant proteins (several expression systems: CHO, HEK cells, E;coli, in vitro system...), cells - Standard quality, endofree or high grade quality (GMP Like) Development of expression vectors, gene design, cell lines and stable pools, murine hybridomas Recombinant antibodies: Antibody Sequencing, Chimerization and Humanization, characterization and validation (specificity, affinity, bioactivity) Analytical platform: ELISA, Blotting, Cytometry, OCTET, PCR and qPCR ...: development of methods, validation of procedures, analysis and quality control A range of FastELISA kits for the quantification of human, mouse, rat, and contaminant Ig (bovine Ig, protein A, etc.). Antibodies anti rabies for ELISA applications RD-Biotech is a company of the mAbexperts group (www.mabexperts.com)

RD-Biotech

3 rue Henri Baigue Besançon, 25000 FranceA French company founded in 2002, RD-Biotech has a complete technical platform and a high-level scientific expertise in molecular biology, recombinant proteins, antibody and cellular engineering. Customized services tailored to the needs of R & D, preclinical and clinical projects: Bioproduction and purification: Plasmids (up to grams), monoclonal antibodies (up to several grams) recombinant antibodies and recombinant proteins (several expression systems: CHO, HEK cells, E;coli, in vitro system...), cells - Standard quality, endofree or high grade quality (GMP Like) Development of expression vectors, gene design, cell lines and stable pools, murine hybridomas Recombinant antibodies: Antibody Sequencing, Chimerization and Humanization, characterization and validation (specificity, affinity, bioactivity) Analytical platform: ELISA, Blotting, Cytometry, OCTET, PCR and qPCR ...: development of methods, validation of procedures, analysis and quality control A range of FastELISA kits for the quantification of human, mouse, rat, and contaminant Ig (bovine Ig, protein A, etc.). Antibodies anti rabies for ELISA applications RD-Biotech is a company of the mAbexperts group (www.mabexperts.com)

REGISTRAT-MAPI

27 rue de la VilletteREGISTRAT-MAPI offers clinical research services including project management, site management, data management, quality assurance, and regulatory assessment with expertise in late phase.

Randox

ZAC du Moulin, 24-26 Rue du Noyer, BP40, 95700 Roissy en FranceRandox Laboratories, through its business units, offer diagnostic services, life science reagents, biomarker testing services, antibody/drug assay development, and toxicology services.

RTI Health Solutions

2bis rue Tête d'Or Lyon, 69006 FranceRTI Health Solutions is the place you turn when you need substantiated, authoritative evidence and advice. We are scientists first—academically-trained, credentialed researchers who know how and when to apply the appropriate research methodologies to your real-world applications and situations. We care about doing what’s right and what’s relevant, so you can make good, safe, and timely decisions about your pharmaceutical, medical device, or diagnostic products. Full range provider of health economics and outcomes research (HEOR), RWE, market access and pharmacoepidemiology services. Also a niche provider of GI clinical trials. Multinational & Multidisciplinary: A global perspective Located across the US and Europe, our staff have led projects in approximately 70 countries. Their experience is diverse; encompasses economics, public health, psychology, epidemiology, statistics, engineering, and other disciplines; and spans both developed and emerging markets, so we can help you with an array of projects in any region of interest. Expertise: Access to key thought leaders We attract and retain top talent across each of our practice areas, so you always have access to key thought leaders in drug development, commercialization, and safety. Nearly 80% of our researchers hold master's or doctorate degrees. Nearly all are published in their fields, many serve as peer-reviewers and editors for research journals, and several maintain university and industry advisory appointments.

Resonance Pharma

2 Allée du Doyen Georges Brus Pessac, Nouvelle-Aquitaine, 33600 FranceResonance Pharma is a CRO specialized in the study of in vivo preclinical pharmacology (drug efficacy and toxicity). Our expertise in Nuclear Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance Spectroscopy (MRS) is proposed to study the efficacy and toxicity of drug candidates in animal models. The proposed methods aim at highlighting the functional effects of drug candidates. As such, we have developed and developed methods and biomarkers adapted to functional studies.

Rhenovia Pharma

Mulhouse, Alsace-Champagne-Ardenne-Lorraine FranceRhenovia Pharma offers drug discovery optimzation services, case studies, first operational services and life science consulting.

Research Pharmaceutical Services

60 rue Carnot F-92100Research Pharmaceutical Services offers manufacturing, formulation, regulatory affairs, quality assurance, molecular modeling, and clinical management.

Raison Aples

190 Route de Gap 04200 SISTERONRaison’Alpes est une société de prestation de services en agriculture, dont les travaux ont pour objectif l’amélioration de la performance économique et environnementale des systèmes de production. Implantée au cœur des Alpes du Sud, les services développés concernent essentiellement les filières arboricoles, céréalières et les plantes à parfum.

Raison Aples

190 Route de Gap Sisteron, Provence-Alpes-Côte d'Azur, 04200 FranceRaison’Alpes est une société de prestation de services en agriculture, dont les travaux ont pour objectif l’amélioration de la performance économique et environnementale des systèmes de production. Implantée au cœur des Alpes du Sud, les services développés concernent essentiellement les filières arboricoles, céréalières et les plantes à parfum.

SATT Conectus Alsace Universite de Strasbourg IPHC Laboratoire de Spectrometrie de Masse BioOrganique (LSMBO)

23 rue du loess - BP28 Strasbourg cedex 2, 67037 FranceL’activité scientifique de l’équipe, créée il y a plus de 20 ans, a pour objectif la détermination structurale de macrobiomolécules, principalement des protéines, avec toute la précision habituellement demandée en chimie, c’est-à-dire sans aucune ambiguïté structurale, jusqu’au dernier atome. Cet objectif inclut la description des complexes biologiques non-covalents. Ces travaux donnent lieu à de nombreuses collaborations avec des biologistes. Protéomique : L’objectif ultime de la protéomique est d’apporter aux biologistes les structures exactes et les quantités précises des milliers de protéines présentes dans une cellule, et ceci éventuellement à très haut débit. Nos efforts se concentrent sur l’amélioration dans la description des structures des protéines (passer de la notion « d’identification » à celle de « caractérisation complète »), y compris pour les modifications post-traductionnelles. Nous développons des stratégies pour identifier des protéines dont seulement quelques copies sont présentes dans la cellule. Nous augmentons nos capacités d’analyses à haut débit, en améliorant les stratégies bioinformatiques pour l’interprétation des données MS/MS aussi bien pour les organismes à génomes séquencés, que pour les organismes à génomes non séquencés (approche de novo haut débit), ce qui n’est abordé que par quelques rares laboratoires au monde. Complexomique : Notre équipe poursuit le développement, de la spectrométrie de masse supramoléculaire. Notre laboratoire avait été le premier à appliquer cette méthodologie très innovante à la caractérisation de supramolécules de synthèse et l’a depuis étendu à l’analyse des complexes biologiques de plusieurs millions de Daltons ouvrant ainsi la voie à une complexomique utilisable en biologie au même titre que la protéomique.

SpinControl

238 Rue Giraudeau Tours, Centre-Val de Loire, 37000 FranceLaboratoire spécialisé dans les tests d'efficacité et de tolérance de tout produit à vocation cosmétique, Spincontrol vous propose des protocoles ""sur-mesure"" des plus classiques aux plus originaux. Spincontrol is specialised in efficacy and safety tests of every claimed cosmetic products and can suggest you ""tailor-made"" protocols from the most standard to the most creative.

STERIXENE

39, Impasse de la Bégude DOMAZAN, Gard, 30390 FranceUV disinfection expert, STERIXENE assists you along your innovative project. From the right idea through to the creation of the technical solution, STERIXENE develops two dry and clean technologies, compact and efficient : Pulsed light and UV LED.

STERIXENE

10 rue du compagnonnage LES ANGLES, Gard, 30133 FranceUV disinfection expert, STERIXENE assists you along your innovative project. From the right idea through to the creation of the technical solution, STERIXENE develops two dry and clean technologies, compact and efficient : Pulsed light and UV LED.

Synapcell

SYNERGY Building ZAC ISIPARC SAINT ISMIER, Isère, 38330 France1. About SynapCell Since 2005, SynapCell’s mission has been to accelerate the discovery of new treatments for patients with brain disorders. True partners of the pharmaceutical industry, we unlock the potential of drug candidates in vivo with our state-of-the-art EEG platform called Cue®. We upgrade the predictive power of rodent models with objective EEG biomarkers of neurological disorders for a smooth translation to the clinic. We study compounds’ pharmacodynamics out of any brain structure and deliver decision-enabling outcomes from off-the-shelf screening, dose-response, phenotyping, or customized exploratory protocols. Striving to advance our understanding of the brain’s pathophysiology, our team engages in authentic collaborative approach with our clients, who recognize SynapCell for its excellent quality of work from project start to finish. 2. Specific Skillsets Supporting Pharmaceutical Neuroscience SynapCell’s cross-functional team of experts possesses know-how in: - Stereotaxic surgery i.e. in cortical and subcortical electrodes implantation for the recording of electrophysiological activities (electrocorticogram and local field potential), - EEG data acquisition: recording spontaneous and evoked EEG activities, - Signal processing, - Data analysis and interpretation, - Pharmacology. 3. Background Knowledge: Applications for drug discovery - Off-the-shelf or customized assays designed for drug discovery applications. - Functional EEG phenotyping and biomarker identification - In vivo Pharmacological testing of neuroactive compounds in freely-moving rodents: - Compound pharmaco-EEG profiling - Head to head drug comparison - Identification of a compound most effective dosing and peak time

SCIEMPATH LABO

7, rue de la Gratiole Larçay, 37270 FranceSciempath Labo (previously Biodoxis) is a company specialized in molecular pathology, created in 2000 to provide expertise in tissue analysis using molecular pathology approaches supporting experimental and translational research. We provide scientific and technical expertise to support your projects through the entire drug development process. Our pathologists and project managers are available to set up investigative and translational pathology studies based on your needs. With both experience of Dr Virgile Richard (DVM, PhD, DES Vet.Path.) and Dr Jacques Bosq (MD), Sciempath Labo has an integrated competence in biology and histopathology for human and translational research. Our mission is to provide expertise in molecular pathology: molecular histopathology combined to biochemistry, genetics and proteomic are necessary to understand molecular alterations and responses to drug therapies.

SCIEMPATH LABO

7, rue de la Gratiole Larçay, 37270 FranceSciempath Labo (previously Biodoxis) is a company specialized in molecular pathology, created in 2000 to provide expertise in tissue analysis using molecular pathology approaches supporting experimental and translational research. We provide scientific and technical expertise to support your projects through the entire drug development process. Our pathologists and project managers are available to set up investigative and translational pathology studies based on your needs. With both experience of Dr Virgile Richard (DVM, PhD, DES Vet.Path.) and Dr Jacques Bosq (MD), Sciempath Labo has an integrated competence in biology and histopathology for human and translational research. Our mission is to provide expertise in molecular pathology: molecular histopathology combined to biochemistry, genetics and proteomic are necessary to understand molecular alterations and responses to drug therapies.

Sup'Biotech

Guy Môquet 94800 66 rue Villejuif France

Silabe ADUEIS (Simian Laboratory Europe)

Chemin du Fort Foch Niederhausbergen, Grand Est, 67207 FranceSilabe offers a large range of NonHuman Primate bioproducts to academic research institutes and companies in the field of Science and Health. Samples from our biobank (blood, serum, plasma…) are collected from healthy captive-bred monkeys housed in Europe, with respect to animal welfare and regulations in force. Sampling is performed under veterinary supervision; the quality and the traceability are guaranteed by the certificate provided with the products. Silabe delivers worldwide, respecting all international rules including CITES permits and sanitary requirements. Biological products of primates from different species (Cynomolgus and Rhesus Macaques, Marmosets…), origin, sex and age are currently available, and we can also provide customized primate products.

Silabe ADUEIS (Simian Laboratory Europe)

Fort Foch, Niederhausbergen FranceSilabe offers a large range of NonHuman Primate bioproducts to academic research institutes and companies in the field of Science and Health. Samples from our biobank (blood, serum, plasma…) are collected from healthy captive-bred monkeys housed in Europe, with respect to animal welfare and regulations in force. Sampling is performed under veterinary supervision; the quality and the traceability are guaranteed by the certificate provided with the products. Silabe delivers worldwide, respecting all international rules including CITES permits and sanitary requirements. Biological products of primates from different species (Cynomolgus and Rhesus Macaques, Marmosets…), origin, sex and age are currently available, and we can also provide customized primate products.

SpecialChem SA

100, rue Petit 75019 Paris FranceSince the year 2000, our teams of industry experts have created the world's largest online professional network dedicated to chemicals and materials. This network includes more than 500,000 engineers, formulators, product developers, marketers, applicators and brand owners across the globe. Through our vertical industry websites, these professionals have unlimited access to Universal Selectors aimed at gathering all chemicals & materials in the world, and the knowledge to select them through high value content such as Product Selection Guides and Online Courses.

SpecialChem SA

100 rue 75019 FranceSince the year 2000, our teams of industry experts have created the world's largest online professional network dedicated to chemicals and materials. This network includes more than 500,000 engineers, formulators, product developers, marketers, applicators and brand owners across the globe. Through our vertical industry websites, these professionals have unlimited access to Universal Selectors aimed at gathering all chemicals & materials in the world, and the knowledge to select them through high value content such as Product Selection Guides and Online Courses.

STERIGENE

2 rue André Citroen Franconville, 95130 FranceSTERIGENE offers process and cleanroom equipment.

STERIGENE

Franconville, Île-de-France, 95130 FranceSTERIGENE offers process and cleanroom equipment.

Synexel

144 rue de la GibauderieSynexel offers analytical chemistry, biomarkers, clinical studies, kinetic studies, formulation, and bioanalytical methods in diverse species and matrices.

Sotax

3 Rue Châteaubriand Orléans, Centre-Val de Loire, 45100 FranceSOTAX leads the way in the development and manufacture of high-quality pharmaceutical testing equipment and associated services. Our equipment is used worldwide in the development and production processes of our customers and the pharmaceutical and science industries. SOTAX develops, produces and markets system solutions for pharmaceutical testing and does so in close cooperation with pharmaceutical and scientific partners. Our extensive market and process know-how enables us to meet our customers’ requirements and comply with the key directives relevant to them. We are also open to cooperation with new industries. SOTAX is a leading independent company for pharmaceutical testing equipment. The company owes its independence to its sustained economic success. The SOTAX Group is a global success story and has subsidiaries around the world that are familiar with local needs and practices. We maintain our competitive edge by excelling in flexibility, performance, quality and safety.

Smartox Biotechnology

Bât BIOPOLIS 5, avenue du Grand Sablon La Tronche, 38700 FranceSmartox Biotechnology is specialised in animal venom research. Smartox offers a catalog of synthetic toxins which modulate ion channels, GPCR and integrins. Smartox has developed an innovative compound library named "VenomScreen" made of 40,000 peptides from animal venoms. This library allows to access a unique chemical space composed of constrained peptides targetting preferentially GPCRs, ion channels, integrins and some of them also demonstrate potent bioinsecticidal and antimicrobial properties. Animal venom toxins have been involved in a wide range of therapeutic area such as autoimmune disease, diabetes, pain, cardiovascular disorders, cancer..

Smartox Biotechnology

570 rue de la chimie saint martin d'hères, 38400 FranceSmartox Biotechnology is specialised in animal venom research. Smartox offers a catalog of synthetic toxins which modulate ion channels, GPCR and integrins. Smartox has developed an innovative compound library named "VenomScreen" made of 40,000 peptides from animal venoms. This library allows to access a unique chemical space composed of constrained peptides targetting preferentially GPCRs, ion channels, integrins and some of them also demonstrate potent bioinsecticidal and antimicrobial properties. Animal venom toxins have been involved in a wide range of therapeutic area such as autoimmune disease, diabetes, pain, cardiovascular disorders, cancer..

Sartorius Stedim Biotech

Zone Industrielle Les Paluds Auenue de Jouques- CS 91051 Aubagne, 13781 FranceSartorius Stedim BioOutsource Ltd. is a leading provider of contract testing services to the global biopharmaceutical and biotechnology industries. BioOutsource has operations in both Europe and the USA, with testing laboratories in Glasgow, UK, and Cambridge, MA, USA. BioOutsource was founded in 2007 and was acquired by Sartorius Stedim Biotech in 2015. We are accredited for cGMP, GLP and GCP and provide contract testing services to assess the quality and safety of biologic drugs and vaccines including: A range of off-the-shelf assays for biosimilar characterization and comparability Biosafety testing of cell banks and bulk harvest as well as cell line stability and lot release At Sartorius, we don’t just perform contract testing services; we are committed to delivering service excellence, with an in-house R&D department, we are constantly adding to our existing portfolio of services to address market demands. Our innovative approach and client management model ensure’s projects are managed efficiently, cost-effectively and delivered on-time.

Sartorius Stedim Biotech

Avenue de JouquesSartorius Stedim BioOutsource Ltd. is a leading provider of contract testing services to the global biopharmaceutical and biotechnology industries. BioOutsource has operations in both Europe and the USA, with testing laboratories in Glasgow, UK, and Cambridge, MA, USA. BioOutsource was founded in 2007 and was acquired by Sartorius Stedim Biotech in 2015. We are accredited for cGMP, GLP and GCP and provide contract testing services to assess the quality and safety of biologic drugs and vaccines including: A range of off-the-shelf assays for biosimilar characterization and comparability Biosafety testing of cell banks and bulk harvest as well as cell line stability and lot release At Sartorius, we don’t just perform contract testing services; we are committed to delivering service excellence, with an in-house R&D department, we are constantly adding to our existing portfolio of services to address market demands. Our innovative approach and client management model ensure’s projects are managed efficiently, cost-effectively and delivered on-time.

SPM-Biocameltec

29 Route Nationale Ennetières-en-Weppes, Hauts-de-France, 59320 FranceSPM-Biocameltec is an R&D service provider for Pharmaceutical Industry, Biotech Companies, University Researchers and Government Agencies. SPM-Biocamaltec provides high quality R&D service across a number of disciplines including pharmacology, toxicology and antibody development and production. We offer a wide variety of animal species, such as rabbits, dogs, cats and other largest animals such as pigs, sheeps, horses, camels….. SPM-Biocameltec has designed dedicated facilities in compliance with all applicable animal welfare and housing requirements. All our work with animals is carryout strictly in accordance with the national regulations, legislation and guidelines and those of the countries of our customers (e.g. 2010/63/EU). SPM-Biocameltec’s mission is to offer the highest quality R&D services within short deadlines to advance our customers projects in a timely and cost effective manner.

SYNSIGHT

23 Boulevard François Mitterrand Laboraoire SABNP - Bat. Maupertuis - Université d'Évry Évry, Île-de-France, 91000 FranceCreated in 2013, SYNSIGHT is a game changer in drug discovery by developing the first platform combining cell-based microscopy that train AI models, to generate new chemical entities. The benefits are to increase the productivity of your R&D and secure your drug discovery programs. Its innovative platform and technologies can be directly applied to RNA-protein and protein-protein interactions. Its cellular assay is unique and is able to qualify and quantify directly in human cells these challenging interactions. The MTBench characterizes the efficacy of small molecule modulators in cell (Hit identification and IC50 measurement). This cellular assay, easy to setup as medium or high-throughput screening level combined to biophysical assays, are then able to train our multiparametric AI models to select and generate new chemical entities.

SYNSIGHT

4 Rue Pierre Fontaine Genopole Entreprises Évry, Île-de-France, 91058 FranceCreated in 2013, SYNSIGHT is a game changer in drug discovery by developing the first platform combining cell-based microscopy that train AI models, to generate new chemical entities. The benefits are to increase the productivity of your R&D and secure your drug discovery programs. Its innovative platform and technologies can be directly applied to RNA-protein and protein-protein interactions. Its cellular assay is unique and is able to qualify and quantify directly in human cells these challenging interactions. The MTBench characterizes the efficacy of small molecule modulators in cell (Hit identification and IC50 measurement). This cellular assay, easy to setup as medium or high-throughput screening level combined to biophysical assays, are then able to train our multiparametric AI models to select and generate new chemical entities.

Synthelis

5 avenue du Grand Sablon Grenoble, 38700 FranceSynthelis is a French biotech company specialized in production, purification and characterization of any type of proteins including difficult-to-express ones such as ion channels, membrane transporters, GPCRs, membrane enzymes and antigens. Based on our proprietary cell-free technology, we offer products and services to deliver functional proteins as proteoliposomes or in a soluble format. As a result we can support pharmaceutical companies, biotech companies and academic teams in applications such as vaccine development, antibody development, drug discovery, protein delivery, in vitro diagnostics and structural biology.

Smart-Bioscience

Rue de la Chimie Saint-Martin-d'Hères, Auvergne-Rhône-Alpes, 38400 FranceSB-PEPTIDE (Formely Smart Bioscience), is a French company specialized in peptide synthesis, peptide engineering and peptide analysis. Peptides are 100% made in France in the company facilities located in the Grenoble area. SB-PEPTIDE is a subdivisary of the worldwide renowned company Smartox Biotechnology for its expertise in animal venom research. Smartox Biotechnology offers compound libraries for screening, analytical services and synthetic peptide toxins in more than 40 countries to pharmaceutical, biotech and academic research laboratories. Smartox Biotechnology has developed an extensive expertise in peptide synthesis, engineering and analysis which is now accessible through SB-PEPTIDE to every scientist requiring peptide services. SB-PEPTIDE offers quality, flexible and reliable services, focused on the satisfaction of our clients. Peptide synthesis services from the Smartox group have been cited in various scientific publications and patents (see section Citations & achievements). SB-PEPTIDE supplies public, pharmaceutical and biotech laboratories, agroscience & cosmetic companies as well as CRO in antibody production for example. The company has already successfully synthesized peptides with up to 120 amino acids in acceptable quantity and purity, with up to 5 disulfide bridges, performed double labeling…

Smart-Bioscience

570 rue de la chimie, Saint Martin d’Hères, 38400 FranceSB-PEPTIDE (Formely Smart Bioscience), is a French company specialized in peptide synthesis, peptide engineering and peptide analysis. Peptides are 100% made in France in the company facilities located in the Grenoble area. SB-PEPTIDE is a subdivisary of the worldwide renowned company Smartox Biotechnology for its expertise in animal venom research. Smartox Biotechnology offers compound libraries for screening, analytical services and synthetic peptide toxins in more than 40 countries to pharmaceutical, biotech and academic research laboratories. Smartox Biotechnology has developed an extensive expertise in peptide synthesis, engineering and analysis which is now accessible through SB-PEPTIDE to every scientist requiring peptide services. SB-PEPTIDE offers quality, flexible and reliable services, focused on the satisfaction of our clients. Peptide synthesis services from the Smartox group have been cited in various scientific publications and patents (see section Citations & achievements). SB-PEPTIDE supplies public, pharmaceutical and biotech laboratories, agroscience & cosmetic companies as well as CRO in antibody production for example. The company has already successfully synthesized peptides with up to 120 amino acids in acceptable quantity and purity, with up to 5 disulfide bridges, performed double labeling…

Smart-Bioscience

6 rue des platanes Saint-Egrève, 38120 FranceSB-PEPTIDE (Formely Smart Bioscience), is a French company specialized in peptide synthesis, peptide engineering and peptide analysis. Peptides are 100% made in France in the company facilities located in the Grenoble area. SB-PEPTIDE is a subdivisary of the worldwide renowned company Smartox Biotechnology for its expertise in animal venom research. Smartox Biotechnology offers compound libraries for screening, analytical services and synthetic peptide toxins in more than 40 countries to pharmaceutical, biotech and academic research laboratories. Smartox Biotechnology has developed an extensive expertise in peptide synthesis, engineering and analysis which is now accessible through SB-PEPTIDE to every scientist requiring peptide services. SB-PEPTIDE offers quality, flexible and reliable services, focused on the satisfaction of our clients. Peptide synthesis services from the Smartox group have been cited in various scientific publications and patents (see section Citations & achievements). SB-PEPTIDE supplies public, pharmaceutical and biotech laboratories, agroscience & cosmetic companies as well as CRO in antibody production for example. The company has already successfully synthesized peptides with up to 120 amino acids in acceptable quantity and purity, with up to 5 disulfide bridges, performed double labeling…

Staphyt

23, Rue de Moeuvres - 62860 INCHY EN ARTOIS - FRANCEThe STAPHYT company was created in France in 1989 to answer the customers´ needs in the field of agronomical research. Thanks to the experience of its 230 employees and the access to 67 stations in Europe, STAPHYT positions itself as a main company in plant protection products, seeds, as well as the management of products registration on the market for our clients. STAPHYT’s ambition is to take up one of the worldwide challenges essential to us all: To feed the population of the world while protecting the environment and getting the means to work for Plant Health as part of a modern and innovative agriculture.

ScreenCell

BioPark Bâtiment D 12, rue Jean-Antoine de Baif 75013 Paris FranceScreenCell provides fast and effective isolating of rare circulating cells.

Sogeti

41-43 rue PergolèseSogeti offers information technology support as well as software and systems development.

Socosur - DUPLICATE

19 Rue de Verdun Suresnes, Île-de-France, 92150 FranceSocosur specializes in chemicals distribution.

SPI Pharma

Chemin du Vallon de Maire 13240 Septemes-Les Vallons FranceSPI Pharma provides development of drug delivery systems, anatacid actives and supplies excipients for tablets, soft gels and effervescents.

Sciences Agro Atlantique

2 Route de Créon, 33370 Sadirac, France

SkinExigence

2 Rue Paul Milleret Besançon, Bourgogne Franche-Comté, 25000 FranceBesançon is the capital of microtechniques and has acquired international recognition in the field of skin biometrology following the works initiated by Professor Pierre AGACHE and pursued by Professor Philippe HUMBERT. Privileged and long-term collaborations and relationships have been developed with many other laboratories and the resulting achievements have enhanced the knowledge of physiological and physiopathological mechanisms, in particular with regard to the microcirculation and the optical and physico-chemical properties of the skin. SKINEXIGENCE S.A.S. was created by Sophie MAC on February 2nd, 2006, in Besançon (France), a city with a rich past, and its premises are located within the University Hospital. The company is therefore very close to the Department of Dermatology directed by Professor Philippe HUMBERT.

Shimadzu

Bd Salvador AllendeShimadzu offers analytical technology, laboratory instruments, testing machines, and scales.

SkinEthic Laboratories

45, rue Saint-Philippe - 06000 - NICESkinEthic Laboratories offers in vitro and in vivo skin model services.

Synprosis

59, avenue sainte victoire Zac Saint Charles Fuveau, 13710 FranceSynprosis specializes in peptide manufacturing to develop and produce a synthetic vaccine designed to fight against HIV.

Southwest France Tumour Bank

FranceThe Virtual Tumour Bank of the Cancéropôle Grand Sud-Ouest allows access to an inventory of the samples stored in each tumour bank of the Greate South-West region, of the University Hospital Centres and Cancer Centres of Bordeaux, Limoges, Montpellier, Nîmes and Toulouse.

Solid Drug Development

8, rue John Grasset CH 1205 Geneva SwitzerlandAt Solid Drug Development, we offer you a broad spectrum of drug development services, including technology transfer operations. Our expertise ranges across CMC, non-clinical, clinical, regulatory and strategic concerns and we strive to provide you with the best possible solutions.

Synkem

47, Rue De Longvic - B.P. 50Synkem offers API and intermediate synthesis services.

Scienomics

17 square Edouard VII Paris, 75009 FranceScienomics is a software company specialized in molecular modeling and simulations of materials.

Scienomics

Paris, Île-de-France FranceScienomics is a software company specialized in molecular modeling and simulations of materials.

SMALTIS

2 Rue Paul Milleret BESANCON, 25000 FranceSMALTIS is a company created by two doctors in bacteriology, Sophie GUENARD and Cédric MULLER. Its team is composed of experts in microbiology, who aim to support various public and private actors in their health product development projects, from research to clinical studies. SMALTIS thus, offers tailor-made solutions with high added value, to fight against antibiotic resistance, to explore microbiota, and to optimize bioprocesses through bacterial strain engineering and vector optimization. SMALTIS’ services and products allow, for example, to assess the risk of antimicrobial resistance of a new antimicrobial candidate, to understand the interactions between a compound and the intestinal microbiota, or to build a modified bacterial strain to simplify a bioproduction process. Catalogues of clinical or reference strains, genetically modified or not, well characterized, are also available, as well as analytical services. In order to ensure a high level of quality for its customers, the laboratory is certified ISO 9001.

Socosur Tox Services

54 Rue de Londres Paris, Île-de-France, 75008 FranceWe are developing HBELs Permitted Daily Exposure (PDE) and Occupational Exposure Limit (OEL) as per EMA/CHMP/ CVMP/ SWP/169430/2012 and Occupational Exposure Limits and its banding, especially Safebridge / Naumann banding scheme for calculation of the upper limit in the workplace and product categorization according to NTP 798, up to the development of corresponding Health Surveillance Protocols. The PDE and OEL of more than 1000 APIs are available. We can develop the HBEL of any substance: we have the know how, when no information is available, to perform toxicity evaluation from alternative methods (Q)SAR. When dermal exposure we offer Surface Guidance Limit (SGL) We offer package of PDE / OEL / Safety Data Sheet (SDS) for New Chemical Entities (NCE). For substances which are not an API, we offer DNEL (Derived No Effect Level). Our prices are competitive and rebates are granted on extended quantities. Our other toxicological services are : We are performing QSAR in silico ICH M7 Mutagenic impurities We can perform all your EU required Environmental Risk Assessments to be supplied at a reduced cost with any EU Marketing Authorization appliance as per directive 2001/83/EC We also developed a pioneering solution for stability programs that face an Out of Specifications issue We can save your stability program by full characterization of such impurity and resetting its specification value

Syncrosome

Marseille, Provence-Alpes-Côte d'Azur FranceSyncrosome - your partner in preclinical in vitro and in vivo drug evaluation. Our pharmacological expertise is centred in three areas: 1) In vitro Proof of Efficacy in the fields of CNS ( Parkinson, Stroke, Alzheimer and Neuroinflammation) 2) In vivo Proof of Efficacy - in the fields of respiratory system, cardiovascular system, gastroenterology and central nervous system. 3) Early Pharmacokinetics - on different species 4) Early Safety - using innovative and appropriate methods of functional exploration

SGS Life Science Services

Oignies 2 Rue George Sand ZA Pierre Loti, Oignies, 62590 FranceSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. With over 40 years of experience as a global contract research organization, our global Life Sciences team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. Our health science laboratory services provide you with an international reach and employ the latest technology and methodologies – so that you get the most accurate and reliable results. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs. We provide experience in meeting both international and local regulations across North America, Europe and Asia-Pacific.

SGS Life Science Services

29 Avenue Aristide Briand Arcueil , 94110 FranceSGS helps pharmaceutical, biopharmaceutical, and medical device companies by providing services along the entire drug development pathway. With over 40 years of experience as a global contract research organization, our global Life Sciences team provides integrated solutions from preclinical activities to Phase I-IV clinical trials, bioanalytical, pharmaceutical development, biologics characterization, biosafety, and quality control testing of small and large molecules, raw materials, containers and finished products. Our health science laboratory services provide you with an international reach and employ the latest technology and methodologies – so that you get the most accurate and reliable results. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs. We provide experience in meeting both international and local regulations across North America, Europe and Asia-Pacific.

Stem Genomics

IRMB - Hopital Saint Eloi 80 avenue Augustin Fliche Montpellier Cedex 5, Hérault, 34295 FranceStem Genomics develops a technology invented by Prof John De Vos and Dr Said Assou, researchers at the Institute for Regenerative Medicine & Biotherapy (IRMB), University of Montpellier, and co-founders of the company. Located at the heart of the University Hospital Centre of Montpellier, IRMB houses research groups working on basic stem cell research and on innovative applications for regenerative therapy, with the aim of facilitating the transfer from research to clinical applications. Stem cell genomic integrity Stem cells are at the heart of many of tomorrow personalized therapies. They are the main source of cells for regenerative medicine, the aim of which is to replace damaged tissues. Stem cells are also used in basic medical research to mimic normal or diseased tissues in vitro, the so called “patient in a dish” approach. Cultured stem cells have the advantage to quickly multiply in virtually unlimited quantities, and to potentially differentiate into any cell type. Therefore, they are ideal for in vitro tissue modelling for research, and for producing cells for clinical use. However, like any other cultured cell, stem cells are subject to selection pressures that favour the appearance of genomic abnormalities that can compromise their use in research and in clinical applications. Therefore, stem cell genomic integrity must be routinely monitored over time for their optimal use in R&D and regenerative medicine. Stem Genomics provides specific services to assess the genetic integrity of stem cells. We offer a range of innovative tests based on digital PCR and a panel of specific probes to detect most of the recurrent genetic abnormalities observed in stem cells. This innovation, called iCS-digital, is rapid, robust, and cost-effective, and can be performed on genomic DNA, cell pellets and cells in fresh culture media (or in cell culture supernatant). Thsis technology allows an efficient in-process control for stem cells in culture.

Synelvia

516 rue Pierre et Marie Curie Prologue Biotech Labège cedex, 31670 FranceSynelvia is a CRO dedicated to the analysis of biomarkers and evaluation of drugs effects in the areas of cardio-metabolic, dermatology and cosmetology using innovating technologies

Stago

3 allée Thérésa CS 10009 92665 Asnières sur Seine Cedex FranceThe Stago Group has therefore developed and acquired its expertise over many years, accompanying, and often leading, the rapid growth of this Haematology-related scientific discipline. Which is why Stago is today the only independent international group in the In Vitro Diagnostics industry dedicated to Haemostasis and Thrombosis exploration.

Separex

Champigneulles, Grand Est FranceSeparex provides supercritical and high pressure technology applications and systems.

STE Engipharm

Résidence Boissy, 4STE Engipharm installs clean rooms and designs pharmaceutical process systems including water production plants.

Selexis

18 chemin des AulxSelexis offers mammalian cell line development and cell line technology products and services.

Selexis

Plan-les-Ouates, GE SwitzerlandSelexis offers mammalian cell line development and cell line technology products and services.

SBM Formulation

ZI Avenue Jean Foucault CS621, 34500 Beziers, FranceOur mission: Our formulation facilities and our development, piloting and technical know-how are available to the leading crop protection firms. Our ambition is to be the major European service provider for the crop protection industry, by offering innovative solutions for sustainable agriculture. Our values: Delivering high-quality development, industrialization and formulation services to our customers is our priority and our core value. We also emphasize the transparency of our industrial activities, resulting from our responsible behaviour. We pay particular attention to the health and safety of our employees, the protection of the local population and respect for the environment.

SynAging

Institut Polytechnique National de Lorraine 2 avenue de la Forêt des Haye 54500 Vandœuvre-lès-Nancy, FranceProviding clients with acutely induced phenotypic models of proteopathic neurodegenerative diseases, accelerating drug discovery of symptomatic and disease-modifying therapeutics.

SynAging

24-30, rue Lionnois 54000 Nancy, FranceProviding clients with acutely induced phenotypic models of proteopathic neurodegenerative diseases, accelerating drug discovery of symptomatic and disease-modifying therapeutics.

Stem Alpha

Saint-Genis-l'Argentière, Auvergne-Rhône-Alpes, 69610 FranceStem Alpha offers custom manufacturing and media for the cornea, hematopoietic cells, murine cells, and other research activities.

Scanelis

9 Allée Charles Cros Colomiers, Occitanie, 31770 FranceThe Scanelis laboratory is specialised in molecular diagnostics in the field of animal health. Specialist in real-time PCR (Polymerase Chain Reaction), Scanelis offers approximately 45 real-time PCR assays, for the detection/quantification of infectious agents in many animal species (dogs, cats, birds, ferrets, exotics, cattle, sheep and goats, poultry and rabbits, horses, fishes). Scanelis also provides support to industry, biotechs, lab animal suppliers and research labs: * health monitoring for laboratory animals * real-time PCR genetic testing * quality control of biopharmaceuticals by real-time PCR testing * diagnostics performed in accordance with a customer’s specifications or prescribed quality plan, for instance with the European Pharmacopoeia recommendations. * custom-designed investigations: molecular typing of isolates or strains, infection monitoring and epidemiological monitoring, pathogens or mRNA quantification, cloning and DNA quantification

SAFE (Scientific Animal Food & Engineering)

Route de Saint-Bris Augy, Bourgogne Franche-Comté, 89290 FranceSAFE (Scientific Animal Food & Engineering) designs, formulates and produces lab diets and custom diets for the international research community.

SPS Pharma Services

28 Place Henri Dunant. Clermont-Ferrand FR-63000 FranceSPS Pharma Services offers feasibility studies, dosage forms, APIs, and dissolution testers.

StemCell Technologies

7 rue du lac St Egrève, 38120 FranceKeep your experiments running efficiently with a reliable supply of high-quality, ethically sourced human primary cells* from STEMCELL Technologies. With personalized service, custom products, flexible delivery times, and multiple size options, we help you get the cells you need. Fill out this form to request information about introductory offers to try STEMCELL’s human primary cell products. ####################################################################################################### STEMCELL Technologies supports life scientists with more than 2,500 specialized tools and services. Scientists use our high-quality cell culture media, cell separation technologies, instruments, primary and cultured cells, accessory products, and services to perform stem cell, immunology, cancer, regenerative medicine, and cellular therapy research globally.* STEMCELL’s Contract Assay Services (CAS) specializes in primary cell-based assays and has performed drug toxicity and efficacy testing studies for over 120 pharmaceutical, biotechnology, government, and academic life science organizations worldwide. Our portfolio** of ready-to-use, fresh or cryopreserved human primary cells from blood, cord blood, and bone marrow includes: Leukopaks LRS Cones Mobilized Peripheral Blood Mononuclear Cells (MNCs) Purified Immune Cells (NK, T cells, Monocytes, B cells, Macrophages, Pan-T cells, Dendritic cells) SF-Cultured Immune Cell Subsets (Dendritic cells, Macrophages) Stem Cells (CD34+ cells) Stromal Cells (MSCs) STEMCELL also offers a wide range of disease-state samples and customizations for your needs. Schedule the collection and delivery of fresh cells** at your convenience, or reserve entire lots of cryopreserved cells while you test them in your assays. All human primary cell products are ethically sourced using consent forms and protocols approved by either an Institutional Review Board, the Food and Drug Administration, the U.S. Department of Health and Human Services, and/or an equivalent regulatory authority. See our complete product listing at www.stemcell.com/cells. If you have a question about ready-to-use fresh or frozen human primary cells from STEMCELL, please contact us. *STEMCELL employs more than 1,400 people globally and has facilities in nine countries. Three locations are in North America: our headquarters in Vancouver, Canada, a Sales support office in Cambridge, MA and a distribution center in Seattle, WA. We also have three offices in Europe and five in Asia Pacific to provide comprehensive services to our customers in these areas. In addition to direct sales and support in more than 30 countries throughout North America, Europe, Asia and Australia, we work with a network of distributors to reach and service all other customers across the globe. For full contact information worldwide, visit our locations page for specific details. **Certain products are only available in select territories. Please contact your local sales representative or the Product & Scientific Support team at techsupport@stemcell.com for further information.

StemCell Technologies

40 rue des Berges Miniparc Polytec, Bâtiment Sirocco Grenoble, France, 38000 FranceKeep your experiments running efficiently with a reliable supply of high-quality, ethically sourced human primary cells* from STEMCELL Technologies. With personalized service, custom products, flexible delivery times, and multiple size options, we help you get the cells you need. Fill out this form to request information about introductory offers to try STEMCELL’s human primary cell products. ####################################################################################################### STEMCELL Technologies supports life scientists with more than 2,500 specialized tools and services. Scientists use our high-quality cell culture media, cell separation technologies, instruments, primary and cultured cells, accessory products, and services to perform stem cell, immunology, cancer, regenerative medicine, and cellular therapy research globally.* STEMCELL’s Contract Assay Services (CAS) specializes in primary cell-based assays and has performed drug toxicity and efficacy testing studies for over 120 pharmaceutical, biotechnology, government, and academic life science organizations worldwide. Our portfolio** of ready-to-use, fresh or cryopreserved human primary cells from blood, cord blood, and bone marrow includes: Leukopaks LRS Cones Mobilized Peripheral Blood Mononuclear Cells (MNCs) Purified Immune Cells (NK, T cells, Monocytes, B cells, Macrophages, Pan-T cells, Dendritic cells) SF-Cultured Immune Cell Subsets (Dendritic cells, Macrophages) Stem Cells (CD34+ cells) Stromal Cells (MSCs) STEMCELL also offers a wide range of disease-state samples and customizations for your needs. Schedule the collection and delivery of fresh cells** at your convenience, or reserve entire lots of cryopreserved cells while you test them in your assays. All human primary cell products are ethically sourced using consent forms and protocols approved by either an Institutional Review Board, the Food and Drug Administration, the U.S. Department of Health and Human Services, and/or an equivalent regulatory authority. See our complete product listing at www.stemcell.com/cells. If you have a question about ready-to-use fresh or frozen human primary cells from STEMCELL, please contact us. *STEMCELL employs more than 1,400 people globally and has facilities in nine countries. Three locations are in North America: our headquarters in Vancouver, Canada, a Sales support office in Cambridge, MA and a distribution center in Seattle, WA. We also have three offices in Europe and five in Asia Pacific to provide comprehensive services to our customers in these areas. In addition to direct sales and support in more than 30 countries throughout North America, Europe, Asia and Australia, we work with a network of distributors to reach and service all other customers across the globe. For full contact information worldwide, visit our locations page for specific details. **Certain products are only available in select territories. Please contact your local sales representative or the Product & Scientific Support team at techsupport@stemcell.com for further information.

The Institut Curie Next Generation Sequencing (NGS) Platform

26 rue d’Ulm Paris , 75248 FranceThe NGS Platform of the Institut Curie has greatly evolved since 2012 mainly with the financial support of ICGEx grant obtained in the frame of the EQUIPEX « investissement d’avenir » competitive call. This grant allowed to purchase high throughput NGS sequencers, to fully equip a dedicated lab at the 7th floor of the hospital and expand the staff in charge of running sequencing projects. Under the supervision of Olivier Delattre and Alain Nicolas, the NGS platform provides state of the art services in sequencing. This includes the organization of pre-run meetings where the choice of the most appropriate technical strategy is defined in order to best address the biological question of collaborators. Multiple sequencing protocols have been developed and routinely used in the platform to cover most commonly used applications in genetics and epigenetics (Genome, Exome and targeted resequencing, RNA sequencing, DNA methylation sequencing, ChIP-seq …). Furthermore, we are also willing to co-develop more specific protocols according to the need of research teams of the Institute.

Transgenic Rabbit Models

2-4, rue Jean Baptiste HuetTransgenic Rabbit Models offers transgenic rabbit models for the study of atherosclerosis, ophtalmology, hypertrophic myopathies, diabetes, obesity, hemostasis, respiratory diseases, AIDS, and cancer.

tebu-bio

39 rue de Houdan BP 15 Le Perray-en-Yvelines, 78612 Francetebu-bio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

tebu-bio

39 Rue de Houdan Le Perray-en-Yvelines, Île-de-France, 78610 Francetebu-bio is a leading European distributor of innovative life science research reagents and lab services. Our extensive network of local offices and sales representatives spanning 9 countries daily assists researchers from universities, pharma, cosmetic and biotech companies in choosing and optimally using the products suited to their research programs . For almost 20 years now, tebu-bio’s own laboratories provide R&D contract services and are an active member of recognized professional networks and clusters (Medicen, Cosmetic Valley... Lab services: tebu-bio ISO9001 certified laboratory possesses 4 major platforms: Biomarkers, Protein Production, Molecular Biology and Cell culture. Biomarkers services: tebu bio provides protein quantification and profiling services, gene and miRNA profiling. For protein quantification, the offer includes quantitative measurement of multiple cytokines, chemokines, adipokines, MMPs... in a wide variety of sample types (cell/tissue lysates, serum/plasma, cell culture supernatants...) on robust assays: antibody array or multiplex ELISA format. In addition, we provide one stop pathway focused or broad profiling services including both sample processing and data analysis. If you don't have the expertise or resources to process array data, tebu-bio's biostatistics and bioinformatics partners can do this for you and provide a full report (heat map, cluster and pathway analysis, biomarker selection...). Application examples: inflammation, apoptosis, obesity biomarker monitoring, signalling pathway identification with broad profiling phosphorylation arrays, glycans or glycan/protein interactions detection, miRNA/gene expression profiling... Human Biological samples & Prospective collections: tebu-bio holds an import/export/handling/storage HBS permit and strictly follows regulatory and ethics guidelines related to human biospecimens collection. -Healthy and Diseased blood derived samples (whole blood, plasma, serum, buffy coat, PBMC, platelets...). -Any type of biofluids -Fresh or frozen tissues, healthy or diseased with mutation characterization possibilities -Broad Primary cells offer (healthy or diseased): Human cryo-preserved Hepatocytes, individual donors or pools, Human Hepatic Stellate Cells, Human dermal fibroblast and keratinocytes, Fresh pancreatic human Islets, Human pre-adipocytes, Human Mesenchymal Stem Cells, Peripheral Blood Mononulear Cells (PBMCs), Peripheral Blood Monocytes CD14+, Bone marrow derived CD34+ cells, Tenocytes, Chondrocytes and Synoviocytes, Primary cells from Lung, kidney, Intestine tissues, iPSC derived cardiomyocytes, iPSC derived neurons. Ready to use QC tested specialized media for every primary cell type. Now tebu-bio is the exclusive European distributor of Japanese Collection of Research Bioresources Cell Bank (JCRB), which is one of the most comprehensive cell banks (more than 1 300 cell lines) for Life Scientists and collects high quality cell lines from numerous species such as animal and humans including cancer and genetically modified cells. Protein production (E. coli, HEK293) : tebu-bio provides services from A to Z: gene synthesis, cloning, small scale protein expression to optimize production conditions, large production batches. Our experts have extensive experience and expertise in protein purification and characterization, they will accompany you all along your project. Other services: cell biology (cell amplification & differentiation, cell-line engineering, Spheroids production...); 3D cell culture; hypoxia and normoxia culture conditions; molecular biology, bio-assays (gene reporter & nuclear receptor assays, outsourcing of any assays commercialised by tebu-bio...) Products offer: research antibodies, ELISAs, arrays, proteins & peptides, cell-based & functional assays, primary cells & media (incl. cytokines and growth factors), stem cells and iPS cells, characterized cell lines (ex. melanoma, brain- and stem-cell derived, cell line engineering tools (si/shRNA,CRISPR), biochemicals & compounds, functional assays (actin, tubulin, lipid research tools...).

TFChem

Voie de l’innovation Pharma Parc II Chaussée du Vexin Val de Reuil, 27100 FranceTFChem specializes in fluorochemistry and offers synthesis of fluorinated molecules.

Tremplin I2C Carnot

Esplanade de la paix CS 14032 CAEN cedex 5, 14032 France

Tripos

140bis, Rue de RennesTripos provides natural product and informatics technology services.

Triskel Integrated Services

4, rue des Terreaux-du-Temple Geneva, CH-1201 SwitzerlandTriskel Integrated Services provides a strategic complement to contract research organisations (CROs), contract manufacturers (CMOs) or other classical service providers, offering consulting services throughout the product's lifespan – from discovery through to the post-authorisation phase.

Therassay

IRS-UN 8, quai Moncousu BP 70721 Nantes Cedex 1, 44007 FranceTherassay offers animal models, in vivo, ex vivo, and in vitro testing in various therapeutic areas including metabolism, cardiac, pulmonary, motor, digestive, and oncology.

TransCure bioServices SAS

BioPark le Forum 1-2 260 avenue Marie Curie Archamps, Haute-Savoie, 74160 FranceFull human immune system mouse models for infectious diseases (HIV, Denge, HBV), immuno-oncology, PDX, Inflammatory (IBD, Crohn) and vaccines (100% human IgG) and hu-liver. Efficacy , immunotoxicity and bioequivalence studies. Competitive FTE rate. Truly international company with customers from big pharma and large biotech worldwide. We are the only company providing a transient human cytokine boost to increase the differentiation of NK and myeloid human immune cells in our models. More info at tcbioservices.com. Unique niche expertise for the development of on-demand studies related to the predictability of pre-clinical candidates for diseases listed above.

Takara Bio Europe

34 rue de la Croix de Fer CS 30158 Saint-Germain-en-Laye, 78100 FranceTakara Bio Europe provides kits, reagents, instruments, and services that enable life sciences researchers to achieve their experimental objectives. As a member of the Takara Bio Group, Takara Bio Europe is part of a company that holds a leadership position in the global market and is committed to improving the human condition through biotechnology. Going forward, Takara Bio Europe will continue to develop high-quality, innovative tools and services that accelerate scientific discovery. For researchers in the USA, please visit "Takara Bio USA's profile here":https://app.scientist.com/domain_switcher?redirect=/providers/ba5e2593-0a26-4dda-93b6-b07ddb7823b1

Thorlabs, Inc.

109, rue des Cotes Maisons-Laffitte 78600 FranceFounded in 1989, Thorlabs has its headquarters in Newton, NJ. This location is also home to our mechanics, optics, fiber, advanced systems technology, and advanced applications teams as well as one of our three distribution warehouses. On-site manufacturing allows us to customize our products quickly and efficiently to meet specialized customer requests. Our technical support team, call center, marketing, and web development teams make their homes in Newton as well, and are dedicated to providing comprehensive customer support and services.

Technoflex

Bidart, Aquitaine-Limousin-Poitou-Charentes, 64210 FranceTechnoflex offers design and production of flexible bags and medical devices.

Technoflex

ZA de Bassilour 64210 BIDART FranceTechnoflex offers design and production of flexible bags and medical devices.

Texcell

1 Rue Pierre Fontaine Evry, 91000 FranceTexcell-North America, Inc. is a global contract research organization based in the Maryland/Virginia biotech corridor specializing in custom cell culture, virus propagation, virus concentration, viral clearance services, and viral safety testing in support of biopharmaceutical applications submitted to the FDA and other regulatory authorities. Since 2002, our team has cultivated an ever-increasing range of experience performing viral clearance studies for a wide variety of purification steps including chromatography, filtration, and inactivation methods, as well as evaluations of column age and sanitization, or cleaning efficacy. We offer our clients a personalized and tailored approach to study design with the advantage of an extensive historical viral clearance database of over 9,000 studies performed by our global organization. Through partnerships with other Texcell facilities around the world, we have expanded our services portfolio to include cGMP cell bank production, cell bank characterization and GMP compliant animal studies. We are proud to support research that continues to improve global quality of life.

The Institut Curie Genomics Platform

8è étage, 26 rue d’Ulm Paris, 75005 FranceThe genomics platform provides to basic, translational, and medical research teams with high throughput technological tools for analyzing gene structure and expression in various organisms, cellular models, and tumors. Structural alterations in genomes, such as mutations, gains, amplifications, loss of genomic regions, polymorphisms, allelic imbalances, loss of heterozygosity are identified using SNP arrays, Nanostring analysis, Sanger sequencing, or qPCR. Gene expression is complex and may be addressed at multiple levels. Coding and non-coding transcript for proteins can be quantified using Affymetrix chip for a pangenomic analysis, or using NanoString tools, or via qPCR depending on the number of samples and markers to quantify. The platform analyses the regulation of gene expression by quantifying microRNA, non-coding functional RNA, and other specific types of RNA, which modulate gene expression at various levels (transcription and translation). Such quantifications are performed by using Affymetrix chips or via NanoString multiplexing tools. Technics for quantifying certain epigenetic markers are currently being tested to meet internal demand (OxBS method developed by Cambridge Epigenetix).Other technics to analyse the chromatin conformation are being setup (in situ HiC, Uveal Melanoma project, with Pr. E. Heard) to enrich our portfolio of activities

Theorem Clinical Research

37th-39th, Ledru-Rollin Avenue Office 710 Paris 75012 FranceTheorem Clinical Research offers full service clinical research solutions including DM, biostatistics, programming including CDISC, PM, clinical operations, and regulatory affairs.

TAAM - Transgenesis and Archiving of Animal Models (CNRS)

Rue de la Ferollerie Orléans, Centre-Val de Loire, 45100 FranceThe AARI is a CNRS laboratory at the service of the scientific community for biomedical and pharmaceutical basic research. It offers to the latter a set of services targeted on the availability of murine models. TAAM has 3 specialized components each in a specific field of competence: CDTA (Department of Cryopreservation, Distribution, Typing and Animal Archiving) is a center for the breeding and distribution of transgenic and mutant mice under different health status. Its recognized technical expertise (axenization, in vitro fertilization, re-derivation, ...) combined with the richness of its line catalog makes it a leading player in the distribution of models. The CIPA (Small Animal Imaging Center) provides researchers with innovative 2D and 3D imaging equipment, enabling the development of non-invasive means of exploration. Its close collaborations with leading companies enable the CIPA to implement the latest technologies. SEAT (Transgenic Animal Services) proposes the creation of customized transgenic mouse models (conventional and targeted transgenesis) and the production of modified ES cells. This laboratory also offers the possibility of establishing transgenic lines from founders created on site.

TAAM - Transgenesis and Archiving of Animal Models (CNRS)

3 B, Rue de la Férolerie ORLEANS CEDEX 2 , 45071 FranceThe AARI is a CNRS laboratory at the service of the scientific community for biomedical and pharmaceutical basic research. It offers to the latter a set of services targeted on the availability of murine models. TAAM has 3 specialized components each in a specific field of competence: CDTA (Department of Cryopreservation, Distribution, Typing and Animal Archiving) is a center for the breeding and distribution of transgenic and mutant mice under different health status. Its recognized technical expertise (axenization, in vitro fertilization, re-derivation, ...) combined with the richness of its line catalog makes it a leading player in the distribution of models. The CIPA (Small Animal Imaging Center) provides researchers with innovative 2D and 3D imaging equipment, enabling the development of non-invasive means of exploration. Its close collaborations with leading companies enable the CIPA to implement the latest technologies. SEAT (Transgenic Animal Services) proposes the creation of customized transgenic mouse models (conventional and targeted transgenesis) and the production of modified ES cells. This laboratory also offers the possibility of establishing transgenic lines from founders created on site.

The Institut Curie Chemical Library (CNRS) Platform

26 rue d’Ulm Paris , 75248 FranceThe Institute Curie/CNRS Chemical Library was created from the chemical molecules synthesized by the chemists of the Institute Curie of Paris and Orsay. This academic chemical library, one of the most important of France, contains almost 10000 substances. Such a set of chemicals is constituted not only of the final products, but also of synthetic intermediates obtained during the programs of optimization against various therapeutic targets. Since its creation, 65 years ago, the main motivation of the chemistry laboratory of the Institute Curie has been the discovery of molecules for cancer treatment. A direct consequence of this activity is the existence (often in significant quantities) of samples of several thousands of synthesized compounds. Moreover, advances in proteomics and genomics have led to the discovery of an increasing number of new protein targets with therapeutic potential. The Chemical Library consists of 15,509 unique structures including 9891 compounds available in powder and 9200 compounds available in solution.

TcLand Expression

Halle 13, Bio-Ouest Ile de NantesTcLand Expression provides immunological tests, biomarkers, and personalized medicine.

Theradiag

14 Rue Ambroise Croizat Croissy-Beaubourg, 77183 FranceWith more than 25 years experience of developing, manufacturing, and marketing innovative in-vitro diagnostics, Theradiag is now strengthening its presence in theranostics. Our new name, Theradiag, illustrates this approach. With CE marking in 2010 and the launch in 2011 of the first Lisa-Tracker kits, we are expanding this panel by developing and launching new kits. Our goal is to offer clinicians and patients a wide range of biotherapy monitoring kits. We have built the foundations for this new activity based on our knowledge of autoimmune diseases. In the coming months, we will be extending our offer to assist in the monitoring of biotherapies in other treatment areas, such as infectious diseases and cancer. We will also continue to develop our traditional activity in IVD, and specifically autoimmunity and innovative oncogenetic diagnostics. This technological and innovative evolution will allow Theradiag to better serve its clients and contribute to improving the bio-therapeutic treatments of today and the future.

Telstar Life Science Solutions

28Rue Claude BernardTelstar Life Science Solutions designs, manufactures, sell and support of high technology equipment solutions for the pharmaceutical, biotech and related industries

University of Versailles Saint Quentin en Yvelines (UVSQ)

55 avenue de ParisUniversity of Versailles Saint Quentin en Yvelines (UVSQ) focuses on research with laboratories for cellular biology, microbiology, pathology, oncology, and pharmacology.

University of Geneva - Behavioral Core

1 Rue Michel-Servet Genève, GE, 1206 Switzerland

University of Geneva

4 Boulevard du Pont-d'Arve, Genève, GE 1205, CH

University of Geneva

Bd du Pont-d'Arve 40 Bureau R050 GENEVA 4, CH-1211 Switzerland

Université Claude Bernard Lyon 1

43 boulevard du 11 Novembre 1918Université Claude Bernard Lyon 1 (Claude Bernard University) focuses on research.

University of Lyon

92 rue Pasteur 69361 LYON, cedex 07, CS 30122 FranceThe Université de Lyon is a consortium of higher education and research institutions (COMUE: Communauté d’universités et établissements) located within the two neighboring cities of Lyon and Saint-Étienne. The Université de Lyon is the main French higher education and scientific center outside the Parisian area composed of 4 public universities, 7 grandes écoles and the CNRS (the French National Center for Scientific Research), forming a group of 12 members institutions. The Université de Lyon also assembles 19 associated institutions offering specific disciplinary training programs. Altogether, the Université de Lyon regroups 137,600 students and 168 public laboratories. The Université de Lyon implements and manages large strategic projects with the regional authorities (Région Auvergne-Rhône-Alpes, Métropole de Lyon, Saint-Étienne Métropole) as well as a large network of public and private companies. The Université de Lyon builds its international recognition on the great quality of its faculty members, research teams and teaching departments in various disciplines and more particularly in three strategic domains: Bio health and Society Science and Engineering for Sustainable Society Urbanity and Humanities In cooperation with its network of member and associated institutions, the Université de Lyon implements joint-research centers, offers high-quality targeted internships programs and organizes scientific and academic symposiums. It also coordinates PhD programs for the 17 doctoral schools and fosters strategic international partnerships. The Université de Lyon works as a powerful brand promoting its institutions, academic communities, institutional partners, as well as the Lyon Saint-Étienne area in the same way as renowned international university brands.

University of Bordeaux - Interdisciplinary Institute for Neuroscience (IINS)

146 Rue Léo Saignat Bordeaux, Nouvelle-Aquitaine, 33000 FranceThe Institute for Interdisciplinary Neuroscience (IINS) is a new research center that has officially opened its doors January 1st, 2011. The IINS is part of the "Centre National de la Recherche Scientifique" & the "Université of Bordeaux". The IINS unites researchers with diverse areas of expertise, and creates a highly synergistic environment to promote: > The development of innovative methods and investigation tools, especially those based on molecular biology, physiology, optics, chemistry, physics and computer science. > The application of such tools to push the boundaries of the study of molecular events underlying the activity of the brain. This will include studying the morpho-dynamic and functional properties of the nervous system to understand the complexity of its molecular assemblies and functions at an integrated level. > The development of the Bordeaux Imaging Center (BIC), a core facility of service, training and R & D in cellular imaging of international stature to permit the transfer to the scientific community and industry of the tools developed in IINS. Currently, the IINS project is home to 8 research teams, comprised of about 130 scientists. The IINS is part of a greater plan to expand Neuroscience research in Bordeaux through the Neurocampus project that will see the construction of 12 000 m² of new lab space dedicated to Neuroscience, with teams ranging from molecular to behavioral and patho-physiological studies. These teams are federated in the Federation of Bordeaux Neurocampus (FBN).

University of Montepellier - Data Analysis Core

1919 Route de Mende Montpellier, Occitanie, 34090 FranceWe provide bioinformatics services to the 18 research groups of the institute.

Université de Strasbourg - CNRS IBMC Architecture et Réactivité de l'ARN

UPR 9002 IBMC 15 rue René Descartes 67 084 Strasbourg FranceLes thèmes de recherche développés dans l’Unité 9002 du CNRS portent sur la biologie du monde de l’ARN. Les ARN sont en effet à la base de nombreuses fonctions biologiques (régulation de l’expression génique, traduction, ou infection virale). Ils remplissent leurs fonctions notamment en adoptant des structures spatiales particulières qui leur permettent d'interagir avec leurs partenaires de manière coordonnée. Ces structures contrôlent de nombreux processus biologiques par des mécanismes d’interaction très sélectifs qui sont loin d'être élucidés et dont l'étude ouvre de multiples perspectives tant fondamentales qu’appliquées.

University of Tours PST Animaleries

60 Rue du Plat d'Étain Tours, Centre-Val de Loire, 37000 FranceWelcome to the PST Animaleries website of the University of Tours Scientific and Technical Platform Animal experiments enable us to analyze the functioning of the biological systems of the animal kingdom, based on studies on a living animal which is endowed with sensibility. Most of our basic knowledge in biochemistry, physiology, endocrinology or pharmacology is derived from initial studies in animal models; These studies could not have been carried out in man for ethical and religious considerations. Since 1901, more than 80% of Nobel Prizes in medicine or physiology have been obtained for discoveries based on animal models. Animal experimentation is a legal practice that takes place within a precise regulatory framework defining a field of action, the competencies required, an authority and control mechanisms. Its actors have put in place the means of its evaluation. Recently, a regulatory ethics framework has added to this framework an assessment of the 'why' and 'how' by representatives of the social body. All animal facilities or user establishments (EU) of the University of Tours are grouped together in a Scientific and Technical Platform (PST) 'Pet Shops'. This platform makes available to researchers many conventional pathological and / or transgenic animal models in rodent, rabbit or primate species. PST allows to develop a large number of methods: From minimally invasive methods based on imaging to classical in vivo procedures including surgery, from maintaining conventional lines to breeding specific lines. Already involved in research work with more than fifteen local teams and with external partners, PST Petries has the optimum conditions for the development of university research themes, while offering state-of-the-art equipment Projects in partnership with industry. PST Animaleries also provides regulatory training. Already involved in research work with more than 15 local teams and with external partners, PST Petries has the optimum conditions for the development of university research themes, while offering state-of-the-art equipment Projects in partnership with industry. PST Animaleries also provides regulatory training. Already involved in research work with more than 15 local teams and with external partners, PST Petries has the optimum conditions for the development of university research themes, while offering state-of-the-art equipment Projects in partnership with industry. PST Animaleries also provides regulatory training.

University of Tours PST Animaleries

60 rue du Plat D'Etain Tours cedex 1 , 37020 FranceWelcome to the PST Animaleries website of the University of Tours Scientific and Technical Platform Animal experiments enable us to analyze the functioning of the biological systems of the animal kingdom, based on studies on a living animal which is endowed with sensibility. Most of our basic knowledge in biochemistry, physiology, endocrinology or pharmacology is derived from initial studies in animal models; These studies could not have been carried out in man for ethical and religious considerations. Since 1901, more than 80% of Nobel Prizes in medicine or physiology have been obtained for discoveries based on animal models. Animal experimentation is a legal practice that takes place within a precise regulatory framework defining a field of action, the competencies required, an authority and control mechanisms. Its actors have put in place the means of its evaluation. Recently, a regulatory ethics framework has added to this framework an assessment of the 'why' and 'how' by representatives of the social body. All animal facilities or user establishments (EU) of the University of Tours are grouped together in a Scientific and Technical Platform (PST) 'Pet Shops'. This platform makes available to researchers many conventional pathological and / or transgenic animal models in rodent, rabbit or primate species. PST allows to develop a large number of methods: From minimally invasive methods based on imaging to classical in vivo procedures including surgery, from maintaining conventional lines to breeding specific lines. Already involved in research work with more than fifteen local teams and with external partners, PST Petries has the optimum conditions for the development of university research themes, while offering state-of-the-art equipment Projects in partnership with industry. PST Animaleries also provides regulatory training. Already involved in research work with more than 15 local teams and with external partners, PST Petries has the optimum conditions for the development of university research themes, while offering state-of-the-art equipment Projects in partnership with industry. PST Animaleries also provides regulatory training. Already involved in research work with more than 15 local teams and with external partners, PST Petries has the optimum conditions for the development of university research themes, while offering state-of-the-art equipment Projects in partnership with industry. PST Animaleries also provides regulatory training.

Unither Pharmaceuticals

75 rue Saint LazareUnither Pharmaceuticals is the world's leading contract manufacturer of sterile, unit dose preparations.

Universite Lille Faculte de Medicine Animalerie Haute Technologie

56 Rue du Port Lille, Hauts-de-France, 59800 FranceThe research teams of the Faculty of Medicine have access to state-of-the-art methodological platforms and common services that optimize technical resources and strengthen synergy between the teams: Methodological Platforms - Molecular and cellular imaging - Genomics, proteomics and bioinformatics platform - Cytometry and cell sorting platform - Platform for therapeutic innovation - Biotherapy platform - Experimental resources platform - Platform Imaging - Clinical evaluation platform

Universite Lille Faculte de Medicine Animalerie Haute Technologie

Faculty of Medicine of Lille Lille Cedex , F-59045 FranceThe research teams of the Faculty of Medicine have access to state-of-the-art methodological platforms and common services that optimize technical resources and strengthen synergy between the teams: Methodological Platforms - Molecular and cellular imaging - Genomics, proteomics and bioinformatics platform - Cytometry and cell sorting platform - Platform for therapeutic innovation - Biotherapy platform - Experimental resources platform - Platform Imaging - Clinical evaluation platform

University of Geneva - Proteomics

1 Rue Michel-Servet Genève, GE, 1206 Switzerland

University of Strasbourg

25 Rue Becquerel 25 Rue Becquerel Strasbourg, Grand Est, 67087 FranceThe LSMBO focuses on research in the field of mass spectrometry based- proteomics and protein characterization.

University of Strasbourg

LSMBO ECPM Building R5-0, 25 Rue Becquerel Strasbourg, France FranceThe LSMBO focuses on research in the field of mass spectrometry based- proteomics and protein characterization.

UPJV Université Jules Verne Amiens

1 chemin du Thil Amiens, 80025 FranceThe international is a priority in the strategy of development of the University of Picardie Jules Verne. Its presence on the international scene is manifested by the expansion of its network of partner universities, its participation in major exchange programmes and its accession to the Agence Universitaire de la Francophonie and the Agency National Campus France.

Urosphere SAS

Canal Biotech II 3 rue des Satellites Toulouse, 31400 FranceUROSPHERE is a leading Contract Research Organization specializing in preclinical urogenital, gastro-intestinal and oncological pharmacology assays. We provide the pharmaceutical and biopharmaceutical industries with a unique experimental research platform combining both in vivo models and in vitro assays on human and animal tissues. UROsphere's headquarters, laboratories and animal housing facilities are located in Toulouse, France.

Université de Strasbourg Centre de Neurochimie

5 Rue Blaise Pascal Strasbourg, Grand Est, 67000 France

Université de Strasbourg Centre de Neurochimie

5 Rue Blaise Pascal Strasbourg, 67084 United States

Unipex

Tour Franklin 92042 Paris La Défense Cedex FranceUnipex distributes specialty products including API, excipients, and other formulations.

University Joseph Fourier

Grenoble, 38041 FranceUniversity Joseph Fourier focuses on research in various areas.

UNI Packaging

62127 AverdoingtFlexible packaging solutions across Europe and West Africa UNI Packaging manufactures innovative and quality based flexible packaging solutions for an ever changing and highly demanding international market place. Continual investment has seen its presence grow in over fifteen countries throughout Europe and West Africa, based on a firm commitment to provide flexible packaging of the highest standard at optimum cost.

University of Rouen

Mont Saint Aignan, FranceUniversity of Rouen provides academic collaboration.

Vetcyt

168 Allée des Grands Prés Mérignies, Hauts-de-France, 59710 France Dr. Eve Ramery founded Vetcyt in January 2016. The company provides cytology and hematology diagnostic, continuing education for veterinarians and research support for both university and private environnements. Graduated from Liege Faculty of Veterinary Medicine in 2004, Dr Ramery practiced one year before starting a PhD thesis and becoming assistant in Clinical Pathology in Liege Faculty of Veterinary Medicine (2005-2015). Meanwhile, she underwent her Clinical Pathology residency (2009-2014), multiplying externships in Europe, USA and Canada. In 2014, she became double boarded of the American College of Veterinary Pathology (ACVP, sp. ClinPath) and The European College of Veterinary Clinical Pathology (ECVCP). She authored multiple articles and scientific conferences in France and abroad. (list of publications: https://orbi.uliege.be/simple-search?query=ramery).

ViroScan3D

11 allée des Acacias 01600 TrévouxCreated July 23, 2012, ViroScan3D is a services company and Contract Research, Genomics and Nanogénomique specialized in the service of Infectious Diseases. Spin-off from the University Lyon 1, ViroScan3D comes from the activities of the platform ProfileXpert Lyon-1 University and benefited from the project development Feder P2i -Plateforme Technological Innovation in Infectious Diseases ".

ViroScan3D

8 avenue Rockefeller Aile 2AH Lyon, 69008 FranceCreated July 23, 2012, ViroScan3D is a services company and Contract Research, Genomics and Nanogénomique specialized in the service of Infectious Diseases. Spin-off from the University Lyon 1, ViroScan3D comes from the activities of the platform ProfileXpert Lyon-1 University and benefited from the project development Feder P2i -Plateforme Technological Innovation in Infectious Diseases ".

ViroScan3D

8 avenue Rockefeller LYON, Rhone, 69008 FranceCreated July 23, 2012, ViroScan3D is a services company and Contract Research, Genomics and Nanogénomique specialized in the service of Infectious Diseases. Spin-off from the University Lyon 1, ViroScan3D comes from the activities of the platform ProfileXpert Lyon-1 University and benefited from the project development Feder P2i -Plateforme Technological Innovation in Infectious Diseases ".

VetAgro Sup campus Vétérinaire (BioVetim)

Aile 1 niveau 3 1, avenue Bourgelat Marcy l'Etoile, 69280 FranceBioVetim is an immunoassay laboratory specialized in hormone and biomarker analysis. BioVetim is a testing laboratory involved in preclinical studies for the pharmaceutical industry, chemical industry and CRO.

VetAgro Sup campus Vétérinaire (BioVetim)

1 avenue Bourgelat Marcy l'Etoile, 69280 FranceBioVetim is an immunoassay laboratory specialized in hormone and biomarker analysis. BioVetim is a testing laboratory involved in preclinical studies for the pharmaceutical industry, chemical industry and CRO.

Vyoo Agency

Vyoo Agency 10, rue Yvonne Villeurbanne, 69100 FranceWe are a specialized agency in health economics and market access, based in France (Lyon and Paris). Thanks to our know-how and references, Vyoo Agency is a global leader in the field.

Vivexia

Gemeaux, 21120 FranceVivexia is a privately-held company headquartered in Dijon (FRANCE) and specialized in the evaluation of the efficacy of anti-infectious drug candidates. We are developing a wide range of infectious models that are suited to both preclinical and phase IV studies.

Vivalis

Nantes, Pays de la Loire FranceVivalis offers contract manufacturing of virus, protein, and media products.

VibioSPhen

Prologue Biotech 516, rue Pierre et Marie Curie 31670 Labège - FranceVibiosphen combines expertise in microbiology, molecular biology and pharmacology (in vitro and in vivo) with experience in drug R&D in the field of infectious diseases , immunomodulation and host-pathogen interaction in a large company (Sanofi). As a biotechnology company, we conduct research into potential future therapies against multi-resistant bacteria ( E coli, Pseudomona Aeruginosa, Klebsiella, Acinetobacter, Staph aureus..;) including a large panel of predictive models as pneumonia, urinary tract infection, sepsis, septicemia and inflammation. VibioSphen has at disposal, in this high technical and scientific quality environment with A2L2 laboratories and facilities. VibioSphen provides services drawing on cutting-edge technology to create predictive and translational models for studying small molecules, vaccine or biologics

VibioSPhen

Prologue Biotech 516, rue Pierre et Marie Curie LABEGE, 31670 FranceVibiosphen combines expertise in microbiology, molecular biology and pharmacology (in vitro and in vivo) with experience in drug R&D in the field of infectious diseases , immunomodulation and host-pathogen interaction in a large company (Sanofi). As a biotechnology company, we conduct research into potential future therapies against multi-resistant bacteria ( E coli, Pseudomona Aeruginosa, Klebsiella, Acinetobacter, Staph aureus..;) including a large panel of predictive models as pneumonia, urinary tract infection, sepsis, septicemia and inflammation. VibioSphen has at disposal, in this high technical and scientific quality environment with A2L2 laboratories and facilities. VibioSphen provides services drawing on cutting-edge technology to create predictive and translational models for studying small molecules, vaccine or biologics

Voxcan

ZA des Grandes Terres 1305, Route de Lozanne DOMMARTIN, 69380 FranceVOXCAN is a private CRO type company, created in 2007, which offers innovative preclinical services through medical imaging, making it possible to improve and accelerate the development of new therapies, in an ethical and economic manner (reduction up to to 80% of the number of animals used), and reduce time to market. Infectiology, oncology and osteoarticular pathologies are the main areas of expertise in which Voxcan has strong experience. We carry out all our studies in our new preclinical platform (animal facility and imagery) of 500m2, located near Lyon (France), with bio-containment areas (BSL2 & BSL3). In infectious diseases, we can offer in-vivo efficacy studies of your drug candidates in many models of bacterial infection (osteoarticular infection, biofilm on intravenous, pulmonary, subcutaneous catheter on medical tissue, etc.), but also viral or fungal, requiring bio-containment type 2 (BSL-2). We can also use bioluminescent infectious strains (bacterial or viral) allowing, via optical imaging, real-time monitoring of the infection. Voxcan also has its own type 3 bio-containment zone (BSL-3) for infectious challenges requiring a high level of containment. In oncology, we provide you with preclinical services ranging from the in-vitro determination of the action mechanism of the treatment (chemotherapies, antibodies, ADC, immunotherapies…) to in-vivo studies using subcutaneous (ectopic) or orthotopic murine tumor models (Colorectal, Glioblastoma, Pulmonary, Pancreatic, Gastric, Ovarian, Leukemia, Lymphoma, Myeloma… Cancer models).

WatchFrog

Pépinière Genopole Entreprises 4 rue Pierre Fontaine 91000 Evry FranceWatchFrog offers in vivo drug efficacy evaluation, high throughput screening, eco-toxicological screening, and target validation services.

WatchFrog

Évry, Île-de-France FranceWatchFrog offers in vivo drug efficacy evaluation, high throughput screening, eco-toxicological screening, and target validation services.

Wacker

94, Quai Charles de Gaulle 69463 Lyon Cedex 06 FranceWacker offers contract manufacturing, biologic analysis, and quality control/assurance services.

Xentech

4 rue Pierre Fontaine Evry-Courcouronnes, 91000 FranceXenTech is an oncology preclinical CRO specializing in Patient-Derived tumor Xenografts (PDX). We test anticancer drug activity in our PDXs and identify drug response biomarkers. Cell lines derived from our PDX are available for in vitro assays and we also offer Immuno-Oncology PDX (syngeneic and PBMC humanized models) to test I/O checkpoints and combinations with existing or emerging therapies. Our expertise : World-renowned Breast PDX collection, extensively pubished and characterized for all DDR aspects (HRD scores, RAD51 scores, PARP inhibitor responses,...). Special PDX range (Match-R) focusing on Acquired Resistance to the LATEST targeted Therapies (osimetinib, dabrafenib, trametinib, erdafitinib,...) A large collection of Prostate PD models (cRPCs, ...)

Xentech

4, rue Pierre Fontaine Evry, F 91000 FranceXenTech is an oncology preclinical CRO specializing in Patient-Derived tumor Xenografts (PDX). We test anticancer drug activity in our PDXs and identify drug response biomarkers. Cell lines derived from our PDX are available for in vitro assays and we also offer Immuno-Oncology PDX (syngeneic and PBMC humanized models) to test I/O checkpoints and combinations with existing or emerging therapies. Our expertise : World-renowned Breast PDX collection, extensively pubished and characterized for all DDR aspects (HRD scores, RAD51 scores, PARP inhibitor responses,...). Special PDX range (Match-R) focusing on Acquired Resistance to the LATEST targeted Therapies (osimetinib, dabrafenib, trametinib, erdafitinib,...) A large collection of Prostate PD models (cRPCs, ...)

YOLARX Consultants, SARL

101, rue de Sèvres Lot 1674 Paris, 75279 CEDEX 06 FranceYOLARX is a consulting and research organization that provides expertise and research in real-world investigation of disease epidemiology, drug utilization, safety and effectiveness, risk management planning, including strategy, feasibility assessment, study design and conduct, data analysis and medical writing. Projects that we are involved in support the demonstration of product value to achieve patient access and/or regulatory approval. Our mission is to provide expertise and research of the highest methodological standards that evaluate the benefits and harms of medicines in the real-world, for a global client base. YOLARX Consultants consists of two entities: YOLARX Consultants INC, a Quebec registered company created in 2006, and YOLARX Consultants SARL in Paris, France (created in 2015). YOLARX is comprised of academic health researchers and of professionals with extensive experience in the conduct of real-world investigations, including natural history of diseases and unmet needs, non-interventional studies, post-authorization studies (PAS), and pharmacovigilance/risk management. With a global client base, YOLARX Team is international and is able to conduct research in a large number of local languages. YOLARX is featured in the ENCePP Database of Research Resources at the European Medicines Agency (EMA). Our service offering is divided into three pillars of activities: 1. Safety & Effectiveness Evaluation: Generating real-world evidence using administrative claims databases, electronic health records, registries and ad hoc data collection; synthesizing the evidence through systematic reviews and meta-analysis. 2. Therapeutic Risk Management: State-of-the-art studies including drug utilization studies, knowledge and understanding surveys, implementation of risk minimization interventions, as well as their effectiveness assessment. 3. Pharmacovigilance: From spontaneous reporting to data mining, active surveillance, case population studies, case series, and benefit-risk analysis, safety assessment strategy and methods. For additional information about our company and our services, please visit our website at: www.yolarx.com.

YOLARX Consultants, SARL

101 Rue de Sèvres Lot 1674 Paris, Île-de-France, 75007 FranceYOLARX is a consulting and research organization that provides expertise and research in real-world investigation of disease epidemiology, drug utilization, safety and effectiveness, risk management planning, including strategy, feasibility assessment, study design and conduct, data analysis and medical writing. Projects that we are involved in support the demonstration of product value to achieve patient access and/or regulatory approval. Our mission is to provide expertise and research of the highest methodological standards that evaluate the benefits and harms of medicines in the real-world, for a global client base. YOLARX Consultants consists of two entities: YOLARX Consultants INC, a Quebec registered company created in 2006, and YOLARX Consultants SARL in Paris, France (created in 2015). YOLARX is comprised of academic health researchers and of professionals with extensive experience in the conduct of real-world investigations, including natural history of diseases and unmet needs, non-interventional studies, post-authorization studies (PAS), and pharmacovigilance/risk management. With a global client base, YOLARX Team is international and is able to conduct research in a large number of local languages. YOLARX is featured in the ENCePP Database of Research Resources at the European Medicines Agency (EMA). Our service offering is divided into three pillars of activities: 1. Safety & Effectiveness Evaluation: Generating real-world evidence using administrative claims databases, electronic health records, registries and ad hoc data collection; synthesizing the evidence through systematic reviews and meta-analysis. 2. Therapeutic Risk Management: State-of-the-art studies including drug utilization studies, knowledge and understanding surveys, implementation of risk minimization interventions, as well as their effectiveness assessment. 3. Pharmacovigilance: From spontaneous reporting to data mining, active surveillance, case population studies, case series, and benefit-risk analysis, safety assessment strategy and methods. For additional information about our company and our services, please visit our website at: www.yolarx.com.

YOLARX Consultants, SARL

101, rue de Sèvres Lot 1674 Paris, 75279 CEDEX 6 FranceYOLARX is a consulting and research organization that provides expertise and research in real-world investigation of disease epidemiology, drug utilization, safety and effectiveness, risk management planning, including strategy, feasibility assessment, study design and conduct, data analysis and medical writing. Projects that we are involved in support the demonstration of product value to achieve patient access and/or regulatory approval. Our mission is to provide expertise and research of the highest methodological standards that evaluate the benefits and harms of medicines in the real-world, for a global client base. YOLARX Consultants consists of two entities: YOLARX Consultants INC, a Quebec registered company created in 2006, and YOLARX Consultants SARL in Paris, France (created in 2015). YOLARX is comprised of academic health researchers and of professionals with extensive experience in the conduct of real-world investigations, including natural history of diseases and unmet needs, non-interventional studies, post-authorization studies (PAS), and pharmacovigilance/risk management. With a global client base, YOLARX Team is international and is able to conduct research in a large number of local languages. YOLARX is featured in the ENCePP Database of Research Resources at the European Medicines Agency (EMA). Our service offering is divided into three pillars of activities: 1. Safety & Effectiveness Evaluation: Generating real-world evidence using administrative claims databases, electronic health records, registries and ad hoc data collection; synthesizing the evidence through systematic reviews and meta-analysis. 2. Therapeutic Risk Management: State-of-the-art studies including drug utilization studies, knowledge and understanding surveys, implementation of risk minimization interventions, as well as their effectiveness assessment. 3. Pharmacovigilance: From spontaneous reporting to data mining, active surveillance, case population studies, case series, and benefit-risk analysis, safety assessment strategy and methods. For additional information about our company and our services, please visit our website at: www.yolarx.com.

4P-Pharma

Campus de l'Institut Pasteur de Lille 1 Rue du Professeur Calmette, Lille, 59000 France4P Pharma offers a wide range of preclinical inflammatory models and consultancy expertise in the preclinical inflammatory area. We develop flexible, tailored preclinical programs designed to each therapeutics specificity, from in vitro drug screening to experimental inflammatory models in animals. Acute and chronic inflammation are the cause of severe complications and an established risk factor for life-threatening conditions, including cancer, cardiovascular diseases and stroke. For every R&D studies performed, we ensure an intercross between in vitro, in vivo and ex vivo models along with unbiased laboratory, species and model independency.