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Australian National University CoMBE JCSMR Clinical Suites

131 Garran Road Acton , ACT 2601 AustraliaJCSMR Clinical Suites

Australian National University CoMBE JCSMR Genome Discovery Unit

The John Curtin School of Medical Research Stores Building 131, Garran Road Acton, ACT 2601 AustraliaThe Genome Discovery Unit (GDU) provides custom pipeline development and analysis of high-throughput DNA sequencing results. Our bioinformaticians are available to advise on best practice for standard processing of sequencing data and are versed in a number of key technologies: Processing data from the three major sequencing platforms (Roche 454, Illumina and SOLiD) Sequence data pre-processing (adapter clipping, quality trimming) Alignment to reference genomes De novo assembly Programming in a wide range of languages. We offer limited entry workshops covering important aspects of bioinformatics and data handling: Linux for biologists Statistics for next-generation sequencing Illumina data processing. GDU staff members provide (below-cost) consultancy to ANU groups for bioinformatics projects, including (no-cost) assistance with writing the bioinformatics component of grant applications for work planned to be done through the GDU. The GDU can develop custom pipelines, or provide services which piggy-back on existing pipelines. This service includes figures and visualisation tools for publications. Examples of publications from pipelines developed include: Murine SNP detection from exome capture (Yabas M., The CE. et al. Nature Immunology, 2011). ChIP-seq (Soboleva T et al, A unique H2A histone variant occupies the transcriptional start site of active genes, Nature Structural Biology, 2011). The staff of the GDU receive academic mentoring from two bioinformatic research groups at JCSMR.

Australian National University CoMBE JCSMR Imaging & Cytometry Facility

The John Curtin School of Medical Research Building 131 Garran Road Acton, ACT 2601 AustraliaWelcome to the Imaging and Cytometry Facility (ICF). The ICF is a core facility of The John Curtin School of Medical Research. We provide access to equipment as well on-going support, advice and training in the following areas: Cell sorting (FACS), benchtop cell analysis, fluorescence, confocal and 2 photon microscopy, histology, live cell and animal imaging, data and image analysis, IVIS imaging, micro CT imaging and use of Extracellular Flux Analyzer.

Australian National University CoMBE Australian Phenomics Facility

Hugh Ennor Building 117 Garran Road Canberra, ACT 2601 AustraliaMission The Australian Phenomics Facility supports open access large-scale phenotyping of humans and mice to uncover the biological drivers in human disease. The Facility The Australian Phenomics Facility specialises in the development, characterising and archiving of mouse models of human disease. We have an experienced genomics and bioinformatics capability focussed on the identification of single nucleotide polymorphisms and the phenotyping capability to make the biological associations with probable human disease traits. Our goals are to firstly derive the underlying genetic mechanisms, and then look to extend this across the population and better understand cohort differences and responses. The facility was established in 2005 and receives funding from the Australian Government’s NCRIS, Super Science and CRIS programmes through the Australian Phenomics Network and contributions from the Australian National University. We have an open access policy and support academic and corporate research programmes in Australia and internationally.

Australian National University CoMBE JCSMR ACRF Biomolecular Resource Facility

The John Curtin School of Medical Research Stores Building 131, Garran Road ACTON, ACT 2601 AustraliaThe ACRF Biomolecular Resource Facility (BRF) is a core lab providing researchers with access to state of the art techniques for molecular, genetic and protein-based studies. Our highly skilled people can implement and run new cutting edge technologies in these fields and provide consultancy on projects using BRF services and equipment. Our services are available to researchers at the John Curtin School of Medical Research and ANU, as well as the broader regional scientific community and clients from across Australia's education, research and medical services community. The BRF is a service node of Genomics Australia. Mission Our mission is to enable research. Our goals are: to provide cost-effective services in our core areas to deliver our services efficiently to provide new technologies to keep researchers at the forefront of scientific discovery.

CSIRO

Commonwealth Scientific and Industrial Research Organisation CSIRO Black Mountain Science and Innovation Park, Clunies Ross Street, Acton , Australian Capital Territory, 2601 AustraliaCSIRO, the Commonwealth Scientific and Industrial Research Organisation, is Australia's national science agency and one of the largest and most diverse research agencies in the world.

Triticarte

1 Wilf Crane Crescent, Yarralumla, ACT 2600 AustraliaTriticarte offers whole genome profiling and DNA extraction services for wheat and barley.